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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4,5-dichloro-2-n-octyl-3(2H)-isothiazolone
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Accession:CHEBI:83518 term browser browse the term
Definition:A 1,2-thiazole that is 1,2-thiazol-3(2H)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide.
Synonyms:exact_synonym: 4,5-dichloro-2-octyl-1,2-thiazol-3(2H)-one
 related_synonym: DCOIT;   Formula=C11H17Cl2NOS;   InChI=1S/C11H17Cl2NOS/c1-2-3-4-5-6-7-8-14-11(15)9(12)10(13)16-14/h2-8H2,1H3;   InChIKey=PORQOHRXAJJKGK-UHFFFAOYSA-N;   Kathon 930;   SMILES=CCCCCCCCn1sc(Cl)c(Cl)c1=O;   dichlorooctylisothiazolinone
 xref: CAS:64359-81-5
 xref_mesh: MESH:C080469
 xref: PMID:24850171;   Patent:NZ524752;   Patent:US2010256204;   Reaxys:1110842


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4,5-dichloro-2-n-octyl-3(2H)-isothiazolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Kathon 930 results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Kathon 930 results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Kathon 930 results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Kathon 930 inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        xenobiotic 19528
          4,5-dichloro-2-n-octyl-3(2H)-isothiazolone 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  heteroarene 17448
                                    monocyclic heteroarene 15186
                                      azole 14620
                                        thiazoles 1816
                                          1,2-thiazoles 681
                                            4,5-dichloro-2-n-octyl-3(2H)-isothiazolone 4
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