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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fluxapyroxad
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Accession:CHEBI:83113 term browser browse the term
Definition:An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families.
Synonyms:related_synonym: 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide;   Formula=C18H12F5N3O;   InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27);   InChIKey=SXSGXWCSHSVPGB-UHFFFAOYSA-N;   SMILES=Cn1cc(C(=O)Nc2ccccc2-c2cc(F)c(F)c(F)c2)c(n1)C(F)F
 xref: CAS:907204-31-3
 xref_mesh: MESH:C000591719
 xref: PMID:22999200;   PMID:25039069;   PMID:25146353;   PMID:25151827;   PPDB:2002;   Patent:DE102011017670;   Patent:NZ587123;   Pesticides:fluxapyroxad;   Reaxys:15702063


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fluxapyroxad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa10 annexin A10 increases expression ISO fluxapyroxad results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Arg1 arginase 1 decreases expression ISO fluxapyroxad results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 protein CTD PMID:29294346 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions		 ISO fluxapyroxad results in increased expression of CYP2B6 mRNA; fluxapyroxad results in increased expression of CYP2B6 protein
[fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 protein		 CTD PMID:29294346 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO fluxapyroxad results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO fluxapyroxad results in increased expression of CYP3A4 mRNA
[fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP3A4 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP3A4 protein		 CTD PMID:29294346 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO fluxapyroxad results in decreased expression of CYP7A1 mRNA; fluxapyroxad results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO fluxapyroxad results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pesticide 18067
          antifungal agrochemical 12030
            fluxapyroxad 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  heteroarene 17155
                                    monocyclic heteroarene 14983
                                      azole 14506
                                        diazole 10772
                                          pyrazoles 2331
                                            fluxapyroxad 8
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