phthalimides - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	phthalimides	go back to main search page
Accession:	CHEBI:82851	browse the term
Definition:	A dicarboximide that is phthalimide or derivatives obtained from it by the formal replacement of one or more hydrogens.
Synonyms:	related_synonym:	Formula=C8NO2R5; SMILES=[]N1C(=O)c2c(C1=O)c([])c([])c([])c2[*]

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Rat (1017) Mouse (1098) Human (1036) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (1017)

4,5-dianilinophthalimide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

epidermal growth factor

multiple interactions

4,5-dianilinophthalimide inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

5-Hydroxythalidomide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member A1

affects binding

5-hydroxythalidomide binds to ALDH1A1 protein

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

argininosuccinate synthase 1

affects binding

5-hydroxythalidomide binds to ASS1 protein

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATP synthase F1 subunit alpha

affects binding

5-hydroxythalidomide binds to ATP5F1A protein

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase membrane subunit e

affects binding

5-hydroxythalidomide binds to ATP5ME protein

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

3-hydroxybutyrate dehydrogenase 1

affects binding

5-hydroxythalidomide binds to BDH1 protein

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

carbonic anhydrase 3

affects binding

5-hydroxythalidomide binds to CAR3 protein
5-hydroxythalidomide binds to CA3 protein

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

cytochrome c oxidase subunit 6A1

affects binding

5-hydroxythalidomide binds to COX6A1 protein

NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041

G

cytochrome c oxidase subunit 6B1

affects binding

5-hydroxythalidomide binds to COX6B1 protein

NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001
Ensembl chr 5:85,875,109...85,884,001

G

cytochrome P450, subfamily 2, polypeptide 11

increases metabolic processing

CYP2C18 protein results in increased metabolism of 5-hydroxythalidomide

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily C, polypeptide 6

increases abundance
multiple interactions

CYP2C19 protein results in increased abundance of 5'-hydroxythalidomide; CYP2C19 protein results in increased abundance of 5-hydroxythalidomide
[CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5'-hydroxythalidomide; [CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5'-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5-hydroxythalidomide

PMID:20443640 PMID:24350712

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily j, polypeptide 4

increases metabolic processing

CYP2J2 protein results in increased metabolism of 5-hydroxythalidomide

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

[CYP3A4 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; CYP3A4 protein results in increased oxidation of and results in increased glutathionylation of 5-hydroxythalidomide

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

[CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; CYP3A5 protein results in increased oxidation of and results in increased glutathionylation of 5-hydroxythalidomide

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

enolase 1

affects binding

5-hydroxythalidomide binds to ENO1 protein

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336

G

fatty acid binding protein 1

affects binding

5-hydroxythalidomide binds to FABP1 protein

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

ferritin light chain 1

affects binding

5-hydroxythalidomide binds to FTL protein
5-hydroxythalidomide binds to FTL1 protein

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

glutathione S-transferase alpha 1

affects binding

5-hydroxythalidomide binds to GSTA1 protein

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 5

affects binding

5-hydroxythalidomide binds to GSTA1 protein

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

affects binding

5-hydroxythalidomide binds to GSTM1 protein

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

phosphatidylethanolamine binding protein 1

affects binding

5-hydroxythalidomide binds to PEBP1 protein

NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862

G

regucalcin

affects binding

5-hydroxythalidomide binds to RGN protein

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

ubiquinol-cytochrome c reductase binding protein

affects binding

5-hydroxythalidomide binds to UQCRB protein

NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150

apremilast

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

creatine kinase, M-type

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of CKM protein]

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

glutamic-oxaloacetic transaminase 1

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of GOT1 protein]

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

lactate dehydrogenase A

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased secretion of LDHA protein]

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

mitogen activated protein kinase 1

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK1 mRNA]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 8

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK8 mRNA]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

NFKB inhibitor alpha

multiple interactions

apremilast inhibits the reaction [carfilzomib results in decreased expression of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

apremilast inhibits the reaction [carfilzomib results in increased expression of RELA mRNA]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

folpet

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

increases expression

folpet results in increased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 3

increases expression

folpet results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 5

increases expression

folpet results in increased expression of ABCC5 mRNA

NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253

G

ATP binding cassette subfamily F member 1

increases expression

folpet results in increased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

abhydrolase domain containing 6, acylglycerol lipase

increases expression

folpet results in increased expression of ABHD6 mRNA

NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985

G

acetyl-CoA acyltransferase 1A

increases expression

folpet results in increased expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

folpet results in increased expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA acetyltransferase 2

increases expression

folpet results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

ACD, shelterin complex subunit and telomerase recruitment factor

decreases expression

folpet results in decreased expression of ACD mRNA

NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461

G

angiotensin I converting enzyme

decreases expression

folpet results in decreased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

aconitase 2

increases expression

folpet results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA oxidase 1

increases expression

folpet results in increased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

actin alpha 2, smooth muscle

decreases expression

folpet results in decreased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

adenylate cyclase 6

decreases expression

folpet results in decreased expression of ADCY6 mRNA

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

G

adhesion G protein-coupled receptor L4

decreases expression

folpet results in decreased expression of ELTD1 mRNA

NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225

G

alcohol dehydrogenase 5 (class III), chi polypeptide

increases expression

folpet results in increased expression of ADH5 mRNA

NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591

G

agmatinase

decreases expression

folpet results in decreased expression of AGMAT mRNA

NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276

G

aryl hydrocarbon receptor

increases expression

folpet results in increased expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aldo-keto reductase family 1 member B10

increases expression

folpet results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

5'-aminolevulinate synthase 1

increases expression

folpet results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 1 family, member A1

increases expression

folpet results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

increases expression

folpet results in increased expression of ALDH2 mRNA

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A2

increases expression

folpet results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 7 family, member A1

decreases expression

folpet results in decreased expression of ALDH7A1 mRNA

NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193

G

aldolase, fructose-bisphosphate B

increases expression

folpet results in increased expression of ALDOB mRNA

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

aldolase, fructose-bisphosphate C

increases expression

folpet results in increased expression of ALDOA mRNA; folpet results in increased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

arachidonate 5-lipoxygenase activating protein

decreases expression

folpet results in decreased expression of ALOX5AP mRNA

NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986

G

amidohydrolase domain containing 2

increases expression

folpet results in increased expression of AMDHD2 mRNA

NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095

G

adaptor related protein complex 2 subunit mu 1

increases expression

folpet results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

apolipoprotein A1

increases expression

folpet results in increased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein C3

increases expression

folpet results in increased expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

decreases expression

folpet results in decreased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

decreases expression

folpet results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 1

decreases expression

folpet results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

ARF GTPase 1

increases expression

folpet results in increased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

Rho GTPase activating protein 9

decreases expression

folpet results in decreased expression of ARHGAP9 mRNA

NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524

G

AT-rich interaction domain 4B

increases expression

folpet results in increased expression of ARID4B mRNA

NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906

G

ARF like GTPase 1

increases expression

folpet results in increased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

aryl hydrocarbon receptor nuclear translocator

decreases expression

folpet results in decreased expression of ARNT mRNA

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

folpet results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

cAMP-regulated phosphoprotein 19

increases expression

folpet results in increased expression of ARPP19 mRNA

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arylsulfatase A

increases expression

folpet results in increased expression of ARSA mRNA

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

autophagy related 3

increases expression

folpet results in increased expression of ATG3 mRNA

NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224

G

ATPase phospholipid transporting 11B (putative)

increases expression

folpet results in increased expression of ATP11B mRNA

NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232

G

ATPase Na+/K+ transporting subunit alpha 1

decreases expression

folpet results in decreased expression of ATP1A1 mRNA

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATP synthase F1 subunit alpha

increases expression

folpet results in increased expression of ATP5F1A mRNA

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase F1 subunit beta

increases expression

folpet results in increased expression of ATP5F1B mRNA

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase F1 subunit epsilon

increases expression

folpet results in increased expression of ATP5F1E mRNA

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATPase H+ transporting V1 subunit D

increases expression

folpet results in increased expression of ATP6V1D mRNA

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

axin 1

increases expression

folpet results in increased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

beta-1,4-galactosyltransferase 1

increases expression

folpet results in increased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

BCL2-associated agonist of cell death

increases expression

folpet results in increased expression of BAD mRNA

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

barrier to autointegration nuclear assembly factor 1

increases expression

folpet results in increased expression of BANF1 mRNA

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

BCL2 associated X, apoptosis regulator

multiple interactions

[Sulfur co-treated with folpet co-treated with penconazole] affects the expression of BAX mRNA; [Sulfur co-treated with folpet co-treated with penconazole] results in increased expression of BAX mRNA; [Sulfur co-treated with folpet] affects the expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

decreases expression

folpet results in decreased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL2, apoptosis regulator

multiple interactions

[Sulfur co-treated with folpet] results in decreased expression of BCL2 mRNA

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

3-hydroxybutyrate dehydrogenase 1

decreases expression

folpet results in decreased expression of BDH1 mRNA

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

beclin 1

increases expression

folpet results in increased expression of BECN1 mRNA

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

biglycan

decreases expression

folpet results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e40

increases expression

folpet results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

biogenesis of lysosomal organelles complex-1, subunit 2

increases expression

folpet results in increased expression of BLOC1S2 mRNA

NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653

G

biliverdin reductase A

increases expression

folpet results in increased expression of BLVRA mRNA

NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033

G

bone morphogenetic protein 6

decreases expression

folpet results in decreased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

G

BCL2 interacting protein 3

increases expression

folpet results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

3'(2'), 5'-bisphosphate nucleotidase 1

increases expression

folpet results in increased expression of BPNT1 mRNA

NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503

G

basigin

increases expression

folpet results in increased expression of BSG mRNA

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

BTG anti-proliferation factor 2

increases expression

folpet results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

complement C1q A chain

decreases expression

folpet results in decreased expression of C1QA mRNA

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

decreases expression

folpet results in decreased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

decreases expression

folpet results in decreased expression of C1QC mRNA

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

C2 calcium-dependent domain containing 2

decreases expression

folpet results in decreased expression of C2CD2 mRNA

NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739

G

calcium binding and coiled coil domain 1

decreases expression

folpet results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422

G

calnexin

decreases expression

folpet results in decreased expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

capping actin protein, gelsolin like

increases expression

folpet results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

carbonic anhydrase 9

increases expression

folpet results in increased expression of CAR9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

capping protein regulator and myosin 1 linker 1

increases expression

folpet results in increased expression of CARMIL1 mRNA

NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326

G

CASC3 exon junction complex subunit

decreases expression

folpet results in decreased expression of CASC3 mRNA

NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966

G

caspase 7

increases expression

folpet results in increased expression of CASP7 mRNA

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

catalase

increases expression

folpet results in increased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression

folpet results in decreased expression of CAV1 mRNA

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolae associated protein 2

decreases expression

folpet results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

Cbl proto-oncogene B

increases expression

folpet results in increased expression of CBLB mRNA

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

G

carbonyl reductase 1

increases expression

folpet results in increased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

increases expression

folpet results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

cyclin D2

decreases expression

folpet results in decreased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin E2

increases expression

folpet results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

chaperonin containing TCP1 subunit 6A

decreases expression

folpet results in decreased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

Cd48 molecule

decreases expression

folpet results in decreased expression of CD48 mRNA

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

CD74 molecule

decreases expression

folpet results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cytidine deaminase

increases expression

folpet results in increased expression of CDA mRNA

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cyclin-dependent kinase 19

decreases expression

folpet results in decreased expression of CDK19 mRNA

NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628

G

cyclin-dependent kinase 4

decreases expression

folpet results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 7

increases expression

folpet results in increased expression of CDK7 mRNA

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cyclin-dependent kinase inhibitor 1A

increases expression

folpet results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

decreases expression

folpet results in decreased expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

CEA cell adhesion molecule 1

decreases expression

folpet results in decreased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CCAAT/enhancer binding protein beta

increases expression

folpet results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

centromere protein F

decreases expression

folpet results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centromere protein I

decreases expression

folpet results in decreased expression of CENPI mRNA

NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657

G

carboxylesterase 2C

increases expression

folpet results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

centrin 2

decreases expression

folpet results in decreased expression of CETN2 mRNA

NCBI chr X:150,769,944...150,774,833
Ensembl chr X:150,769,953...150,774,919

G

centrin 3

increases expression

folpet results in increased expression of CETN3 mRNA

NCBI chr 2:12,089,025...12,101,828
Ensembl chr 2:12,089,226...12,101,828

G

charged multivesicular body protein 6

increases expression

folpet results in increased expression of CHMP6 mRNA

NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640

G

calcium and integrin binding 1

increases expression

folpet results in increased expression of CIB1 mRNA

NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423

G

cell death-inducing DFFA-like effector c

increases expression

folpet results in increased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

cold inducible RNA binding protein

decreases expression

folpet results in decreased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

creatine kinase, M-type

decreases expression

folpet results in decreased expression of CKM mRNA

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

claudin 7

decreases expression

folpet results in decreased expression of CLDN7 mRNA

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

CAP-GLY domain containing linker protein 3

decreases expression

folpet results in decreased expression of CLIP3 mRNA

NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184

G

calsyntenin 1

decreases expression

folpet results in decreased expression of CLSTN1 mRNA

NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583

G

clathrin, light chain B

increases expression

folpet results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

carnosine dipeptidase 2

increases expression

folpet results in increased expression of CNDP2 mRNA

NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922

G

Cnksr family member 3

decreases expression

folpet results in decreased expression of CNKSR3 mRNA

NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635

G

calponin 1

decreases expression

folpet results in decreased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

calponin 3

decreases expression

folpet results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

component of oligomeric golgi complex 4

increases expression

folpet results in increased expression of COG4 mRNA

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

collagen type I alpha 1 chain

decreases expression

folpet results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 1 chain

decreases expression

folpet results in decreased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type IV alpha 2 chain

decreases expression

folpet results in decreased expression of COL4A2 mRNA

NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839

G

collagen type VI alpha 2 chain

decreases expression

folpet results in decreased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VI alpha 3 chain

decreases expression

folpet results in decreased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

catechol-O-methyltransferase

increases expression

folpet results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

COPI coat complex subunit beta 2

increases expression

folpet results in increased expression of COPB2 mRNA

NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197

G

COP9 signalosome subunit 5

increases expression

folpet results in increased expression of COPS5 mRNA

NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731

G

cytochrome c oxidase subunit 6B1

increases expression

folpet results in increased expression of COX6B1 mRNA

NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001
Ensembl chr 5:85,875,109...85,884,001

G

carbamoyl-phosphate synthase 1

increases expression

folpet results in increased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

cAMP responsive element binding protein 1

decreases expression

folpet results in decreased expression of CREB1 mRNA

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 3-like 3

increases expression

folpet results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

CREB binding protein

increases expression

folpet results in increased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

cellular repressor of E1A-stimulated genes 1

increases expression

folpet results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich with EGF-like domains 2

decreases expression

folpet results in decreased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

CRK like proto-oncogene, adaptor protein

increases expression

folpet results in increased expression of CRKL mRNA

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

G

cryptochrome circadian regulator 1

increases expression

folpet results in increased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, alpha B

decreases expression

folpet results in decreased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

citrate synthase

increases expression

folpet results in increased expression of CS mRNA

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

G

colony stimulating factor 1 receptor

decreases expression

folpet results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

cysteine and glycine-rich protein 1

decreases expression

folpet results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystathionine gamma-lyase

increases expression

folpet results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin delta 1

increases expression

folpet results in increased expression of CTNND1 mRNA

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

G

cathepsin S

decreases expression

folpet results in decreased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

C-X-C motif chemokine ligand 10

decreases expression

folpet results in decreased expression of CXCL10 mRNA

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

cytochrome b-561

increases expression

folpet results in increased expression of CYB561 mRNA

NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787

G

cytochrome c, somatic

decreases expression

folpet results in decreased expression of CYCS mRNA

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

folpet results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

D-box binding PAR bZIP transcription factor

increases expression

folpet results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

dCTP pyrophosphatase 1

decreases expression

folpet results in decreased expression of DCTPP1 mRNA

NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839

G

DNA-damage inducible transcript 3

increases expression

folpet results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

folpet results in increased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

deoxyribose-phosphate aldolase

increases expression

folpet results in increased expression of DERA mRNA

NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865

G

dihydrofolate reductase

increases expression

folpet results in increased expression of DHFR mRNA

NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713

G

DExH-box helicase 29

decreases expression

folpet results in decreased expression of DHX29 mRNA

NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445

G

iodothyronine deiodinase 1

decreases expression

folpet results in decreased expression of DIO1 mRNA

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

dyskerin pseudouridine synthase 1

decreases expression

folpet results in decreased expression of DKC1 mRNA

G

discs large MAGUK scaffold protein 3

decreases expression

folpet results in decreased expression of DLG3 mRNA

NCBI chr X:65,859,653...65,911,887
Ensembl chr X:65,860,172...65,910,322

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

folpet results in increased expression of DNAJB6 mRNA

NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659

G

deoxynucleotidyltransferase, terminal, interacting protein 2

decreases expression

folpet results in decreased expression of DNTTIP2 mRNA

NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581

G

developmental pluripotency associated 5

increases expression

folpet results in increased expression of DPPA5A mRNA

NCBI chr 8:79,215,341...79,217,282
Ensembl chr 8:79,215,362...79,216,570
Ensembl chr 7:79,215,362...79,216,570
Ensembl chr 1:79,215,362...79,216,570
Ensembl chr 3:79,215,362...79,216,570

G

dermatopontin

decreases expression

folpet results in decreased expression of DPT mRNA

NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639

G

desmocollin 2

increases expression

folpet results in increased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

denticleless E3 ubiquitin protein ligase homolog

decreases expression

folpet results in decreased expression of DTL mRNA

NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890

G

dual specificity phosphatase 3

decreases expression

folpet results in decreased expression of DUSP3 mRNA

NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962

G

dual specificity phosphatase 6

increases expression

folpet results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dynein light chain Tctex-type 3

increases expression

folpet results in increased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

dual specificity tyrosine phosphorylation regulated kinase 3

decreases expression

folpet results in decreased expression of DYRK3 mRNA

NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778

G

E2F transcription factor 2

decreases expression

folpet results in decreased expression of E2F2 mRNA

NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217

G

enoyl-CoA delta isomerase 1

increases expression

folpet results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

extracellular matrix protein 1

decreases expression

folpet results in decreased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

ER degradation enhancing alpha-mannosidase like protein 1

decreases expression

folpet results in decreased expression of EDEM1 mRNA

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

G

early growth response 1

decreases expression

folpet results in decreased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases expression

folpet results in increased expression of EIF2AK2 mRNA

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2 subunit gamma

decreases expression

folpet results in decreased expression of EIF2S3X mRNA

NCBI chr X:58,916,513...58,939,923
Ensembl chr X:58,917,490...58,940,686

G

eukaryotic translation initiation factor 3, subunit G

decreases expression

folpet results in decreased expression of EIF3G mRNA

NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808

G

eukaryotic translation initiation factor 3, subunit I

decreases expression

folpet results in decreased expression of EIF3I mRNA

NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676

G

eukaryotic translation initiation factor 4B

increases expression

folpet results in increased expression of EIF4B mRNA

NCBI chr 7:133,206,637...133,228,436

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

folpet results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4 gamma 1

decreases expression

folpet results in decreased expression of EIF4G1 mRNA

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

ELAV like RNA binding protein 1

decreases expression

folpet results in decreased expression of ELAVL1 mRNA

NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784

G

ELOVL fatty acid elongase 5

decreases expression

folpet results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

ELOVL fatty acid elongase 6

increases expression

folpet results in increased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

EMAP like 3

decreases expression

folpet results in decreased expression of EML3 mRNA

NCBI chr 1:205,826,354...205,837,790
Ensembl chr 1:205,817,378...205,837,807

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

folpet results in decreased expression of ENPP1 mRNA

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

epoxide hydrolase 1

increases expression

folpet results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 2

increases expression

folpet results in increased expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

erb-b2 receptor tyrosine kinase 2

decreases expression

folpet results in decreased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 3

affects expression

folpet affects the expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

endoplasmic reticulum oxidoreductase 1 beta

decreases expression

folpet results in decreased expression of ERO1B mRNA

NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398

G

electron transfer flavoprotein subunit beta

increases expression

folpet results in increased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

Enah/Vasp-like

decreases expression

folpet results in decreased expression of EVL mRNA

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

G

exostosin glycosyltransferase 1

decreases expression

folpet results in decreased expression of EXT1 mRNA

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

G

coagulation factor II (thrombin) receptor

decreases expression

folpet results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

fatty acid binding protein 1

increases expression

folpet results in increased expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 2

increases expression

folpet results in increased expression of FABP2 mRNA

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

fatty acid synthase

decreases expression

folpet results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 1

increases expression

folpet results in increased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

fibrillarin

decreases expression

folpet results in decreased expression of FBL mRNA

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

fibrillin 1

decreases expression

folpet results in decreased expression of FBN1 mRNA

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

F-box protein 5

decreases expression

folpet results in decreased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

Fc epsilon receptor II

increases expression

folpet results in increased expression of FCER2A mRNA

NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476

G

Fc gamma receptor 2A

decreases expression

folpet results in decreased expression of FCGR3 mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

farnesyl diphosphate farnesyl transferase 1

increases expression

folpet results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

fibroblast growth factor 1

decreases expression

folpet results in decreased expression of FGF1 mRNA

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fission, mitochondrial 1

increases expression

folpet results in increased expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 4

decreases expression

folpet results in decreased expression of FKBP4 mRNA

NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833

G

FKBP prolyl isomerase 5

increases expression

folpet results in increased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

filamin A

decreases expression

folpet results in decreased expression of FLNA mRNA

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

flavin containing dimethylaniline monoxygenase 5

increases expression

folpet results in increased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

fibronectin 1

decreases expression

folpet results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

folpet results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box J3

increases expression

folpet results in increased expression of FOXJ3 mRNA

NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489

G

folylpolyglutamate synthase

decreases expression

folpet results in decreased expression of FPGS mRNA

NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563

G

fibroblast growth factor receptor substrate 2

increases expression

folpet results in increased expression of FRS2 mRNA

NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743

G

FYN proto-oncogene, Src family tyrosine kinase

decreases expression

folpet results in decreased expression of FYN mRNA

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

frizzled class receptor 7

decreases expression

folpet results in decreased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

folpet results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

alpha glucosidase

decreases expression

folpet results in decreased expression of GAA mRNA

NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836

G

GABA type A receptor-associated protein

increases expression

folpet results in increased expression of GABARAP mRNA

NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765

G

gamma-aminobutyric acid type A receptor subunit alpha 4

decreases expression

folpet results in decreased expression of GABRA4 mRNA

NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

folpet results in decreased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

UDP-galactose-4-epimerase

increases expression

folpet results in increased expression of GALE mRNA

NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

folpet results in increased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

glycyl-tRNA synthetase 1

decreases expression

folpet results in decreased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

glutamate-cysteine ligase, catalytic subunit

increases expression

folpet results in increased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

folpet results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glial cell derived neurotrophic factor

increases expression

folpet results in increased expression of GDNF mRNA

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

Gfo/Idh/MocA-like oxidoreductase domain containing 1

increases expression

folpet results in increased expression of GFOD1 mRNA

NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938

G

GTPase, IMAP family member 4

decreases expression

folpet results in decreased expression of GIMAP4 mRNA

NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306

G

GTPase, IMAP family member 6

decreases expression

folpet results in decreased expression of GIMAP6 mRNA

NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116

G

glyoxalase domain containing 4

increases expression

folpet results in increased expression of GLOD4 mRNA

NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898

G

glutaredoxin

increases expression

folpet results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutamate-ammonia ligase

decreases expression

folpet results in decreased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

G protein subunit alpha i2

decreases expression

folpet results in decreased expression of GNAI2 mRNA

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

golgi transport 1B

decreases expression

folpet results in decreased expression of GOLT1B mRNA

NCBI chr 4:175,333,056...175,346,156
Ensembl chr 4:175,333,092...175,346,153

G

G protein-coupled receptor 17

increases expression

folpet results in increased expression of GPR17 mRNA

NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966

G

glutathione peroxidase 2

increases expression

folpet results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

increases expression

folpet results in increased expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

growth factor receptor bound protein 7

increases expression

folpet results in increased expression of GRB7 mRNA

NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052

G

glutathione-disulfide reductase

increases expression

folpet results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 2

increases expression

folpet results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

increases expression

folpet results in increased expression of GSTA1 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 2

increases expression

folpet results in increased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase, mu 5

increases expression

folpet results in increased expression of GSTM3 mRNA

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

increases expression

folpet results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glucoside xylosyltransferase 1

increases expression

folpet results in increased expression of GXYLT1 mRNA

NCBI chr 7:124,400,896...124,434,682
Ensembl chr 7:124,400,896...124,434,699

G

granzyme A

decreases expression

folpet results in decreased expression of GZMA mRNA

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

G

granzyme B

decreases expression

folpet results in decreased expression of GZMB mRNA

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

H3 clustered histone 1

decreases expression

folpet results in decreased expression of H3C1 mRNA

NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856

G

HEAT repeat containing 1

decreases expression

folpet results in decreased expression of HEATR1 mRNA

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

heme binding protein 1

increases expression

folpet results in increased expression of HEBP1 mRNA

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

decreases expression

folpet results in decreased expression of HERC6 mRNA

NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744

G

hes family bHLH transcription factor 1

decreases expression

folpet results in decreased expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hexosaminidase subunit alpha

decreases expression

folpet results in decreased expression of HEXA mRNA

NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013

G

Holliday junction recognition protein

increases expression

folpet results in increased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

high mobility group 20 B

increases expression

folpet results in increased expression of HMG20B mRNA

NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

folpet results in decreased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heterogeneous nuclear ribonucleoprotein H1

decreases expression

folpet results in decreased expression of HNRNPH1 mRNA

NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846

G

hook microtubule-tethering protein 2

increases expression

folpet results in increased expression of HOOK2 mRNA

NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181

G

homeo box B3

decreases expression

folpet results in decreased expression of HOXB3 mRNA

NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107

G

heparan sulfate 2-O-sulfotransferase 1

decreases expression

folpet results in decreased expression of HS2ST1 mRNA

NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769

G

hydroxysteroid (17-beta) dehydrogenase 11

increases expression

folpet results in increased expression of HSD17B11 mRNA

NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3

increases expression

folpet results in increased expression of HSD3B3 mRNA

NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033

G

heat shock protein 90 beta family member 1

decreases expression

folpet results in decreased expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1B

increases expression

folpet results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 8

increases expression

folpet results in increased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family B (small) member 1

decreases expression

folpet results in decreased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family B (small) member 6

decreases expression

folpet results in decreased expression of HSPB6 mRNA

NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071

G

heat shock protein family D (Hsp60) member 1

decreases expression

folpet results in decreased expression of HSPD1 mRNA

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

HtrA serine peptidase 1

decreases expression

folpet results in decreased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

hypoxia up-regulated 1

decreases expression

folpet results in decreased expression of HYOU1 mRNA

NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186

G

inhibitor of DNA binding 4

decreases expression

folpet results in decreased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

increases expression

folpet results in increased expression of IDH3G mRNA

NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171

G

interferon induced transmembrane protein 2

decreases expression

folpet results in decreased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

decreases expression

folpet results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

insulin-like growth factor 1

decreases expression

folpet results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

decreases expression

folpet results in decreased expression of IGF1R mRNA

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 mRNA binding protein 2

decreases expression

folpet results in decreased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor binding protein 3

decreases expression

folpet results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 6

decreases expression

folpet results in decreased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

immunoglobulin lambda constant 1

decreases expression

folpet results in decreased expression of IGLC1 mRNA

NCBI chr11:81,947,966...81,949,822
Ensembl chr11:81,947,934...81,949,822
Ensembl chr11:81,947,934...81,949,822

G

inhibitor of nuclear factor kappa B kinase subunit beta

decreases expression

folpet results in decreased expression of IKBKB mRNA

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 18

decreases expression

folpet results in decreased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 receptor type 1

decreases expression

folpet results in decreased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

inositol polyphosphate-4-phosphatase type II B

decreases expression

folpet results in decreased expression of INPP4B mRNA

NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634

G

inositol polyphosphate-5-phosphatase D

decreases expression

folpet results in decreased expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

IQ motif containing GTPase activating protein 1

increases expression

folpet results in increased expression of IQGAP1 mRNA

NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755

G

insulin receptor substrate 1

increases expression

folpet results in increased expression of IRS1 mRNA

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

integrin subunit alpha E

decreases expression

folpet results in decreased expression of ITGAE mRNA

NCBI chr10:57,704,813...57,764,093
Ensembl chr10:57,591,753...57,764,093
Ensembl chr10:57,591,753...57,764,093

G

iodotyrosine deiodinase

increases expression

folpet results in increased expression of IYD mRNA

NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

decreases expression

folpet results in decreased expression of JMJD6 mRNA

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

folpet results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

lysyl-tRNA synthetase 1

decreases expression

folpet results in decreased expression of KARS1 mRNA

NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632

G

lysine acetyltransferase 2A

decreases expression

folpet results in decreased expression of KAT2A mRNA

NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166

G

lysine acetyltransferase 6A

increases expression

folpet results in increased expression of KAT6A mRNA

NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606

G

lysine demethylase 3A

increases expression

folpet results in increased expression of KDM3A mRNA

NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073

G

kinesin family member 23

decreases expression

folpet results in decreased expression of KIF23 mRNA

NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072

G

KLF transcription factor 2

decreases expression

folpet results in decreased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 4

increases expression

folpet results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kelch-like family member 13

decreases expression

folpet results in decreased expression of KLHL13 mRNA

NCBI chr X:113,942,309...114,107,299
Ensembl chr X:113,942,309...114,107,321

G

kelch-like family member 24

decreases expression

folpet results in decreased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 9

decreases expression

folpet results in decreased expression of KLHL9 mRNA

NCBI chr 5:103,333,747...103,337,931

G

keratin 19

increases expression

folpet results in increased expression of KRT19 mRNA

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

keratin 7

decreases expression

folpet results in decreased expression of KRT7 mRNA

NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052

G

keratin 8

increases expression

folpet results in increased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

lysosomal-associated membrane protein 1

increases expression

folpet results in increased expression of LAMP1 mRNA

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

LHFPL tetraspan subfamily member 6

decreases expression

folpet results in decreased expression of LHFPL6 mRNA

NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443

G

lipase A, lysosomal acid type

increases expression

folpet results in increased expression of LIPA mRNA

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lysophosphatidylglycerol acyltransferase 1

decreases expression

folpet results in decreased expression of LPGAT1 mRNA

NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333

G

lecithin retinol acyltransferase

decreases expression

folpet results in decreased expression of LRAT mRNA

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

leucine rich repeat containing 41

decreases expression

folpet results in decreased expression of LRRC41 mRNA

NCBI chr 5:129,554,547...129,575,450
Ensembl chr 5:129,554,547...129,575,449

G

lanosterol synthase

increases expression

folpet results in increased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

lymphotoxin beta receptor

increases expression

folpet results in increased expression of LTBR mRNA

NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539

G

lysophospholipase 1

increases expression

folpet results in increased expression of LYPLA1 mRNA

NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746

G

lysozyme 2

decreases expression

folpet results in decreased expression of LYZ2 mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

MAF bZIP transcription factor F

increases expression

folpet results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

monoamine oxidase A

increases expression

folpet results in increased expression of MAOA mRNA

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

mitogen-activated protein kinase 1 interacting protein 1-like

increases expression

folpet results in increased expression of MAPK1IP1L mRNA

NCBI chr15:20,545,043...20,571,466
Ensembl chr15:20,545,059...20,569,674

G

mitogen activated protein kinase 3

increases expression

folpet results in increased expression of MAPK3 mRNA

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

methionine adenosyltransferase 2A

increases expression

folpet results in increased expression of MAT2A mRNA

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

minichromosome maintenance complex component 7

decreases expression

folpet results in decreased expression of MCM7 mRNA

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

malic enzyme 1

increases expression

folpet results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

Meis homeobox 2

decreases expression

folpet results in decreased expression of MEIS2 mRNA

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

major facilitator superfamily domain containing 10

decreases expression

folpet results in decreased expression of MFSD10 mRNA

NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377

G

MINDY lysine 48 deubiquitinase 1

increases expression

folpet results in increased expression of MINDY1 mRNA

NCBI chr 2:182,859,977...182,873,000
Ensembl chr 2:182,860,472...182,873,015

G

matrix metallopeptidase 14

decreases expression

folpet results in decreased expression of MMP14 mRNA

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

MNAT1 component of CDK activating kinase

decreases expression

folpet results in decreased expression of MNAT1 mRNA

NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744

G

MOB kinase activator 1A

decreases expression

folpet results in decreased expression of MOB1A mRNA

NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561
Ensembl chr 1:115,831,551...115,848,561

G

mortality factor 4 like 2

increases expression

folpet results in increased expression of MORF4L2 mRNA

NCBI chr X:100,082,562...100,093,658
Ensembl chr X:100,082,404...100,093,728

G

mitochondrial ribosomal protein S16

increases expression

folpet results in increased expression of MRPS16 mRNA

NCBI chr15:3,918,621...3,921,024
Ensembl chr15:3,918,615...3,921,656

G

mitochondrial ribosomal protein S2

decreases expression

folpet results in decreased expression of MRPS2 mRNA

NCBI chr 3:11,803,044...11,806,341
Ensembl chr 3:11,801,310...11,806,313

G

mitochondrial ribosomal protein S34

increases expression

folpet results in increased expression of MRPS34 mRNA

NCBI chr10:13,916,024...13,917,155
Ensembl chr10:13,916,026...13,918,406

G

mitochondrial ribosomal protein S6

increases expression

folpet results in increased expression of MRPS6 mRNA

NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484

G

metastasis associated 1

decreases expression

folpet results in decreased expression of MTA1 mRNA

NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

increases expression

folpet results in increased expression of MTHFD1L mRNA

NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905

G

major vault protein

increases expression

folpet results in increased expression of MVP mRNA

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

G

MYC binding protein 2

decreases expression

folpet results in decreased expression of MYCBP2 mRNA

NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498

G

myosin light chain 9

decreases expression

folpet results in decreased expression of MYL9 mRNA

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myosin light chain kinase

decreases expression

folpet results in decreased expression of MYLK mRNA

NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261

G

nascent polypeptide associated complex subunit alpha

increases expression

folpet results in increased expression of NACA mRNA

NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992

G

NCK adaptor protein 1

decreases expression

folpet results in decreased expression of NCK1 mRNA

NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300

G

NADH:ubiquinone oxidoreductase subunit A1

increases expression

folpet results in increased expression of NDUFA1 mRNA

NCBI chr X:116,424,223...116,427,875
Ensembl chr X:116,424,223...116,428,633

G

NADH:ubiquinone oxidoreductase subunit A9

increases expression

folpet results in increased expression of NDUFA9 mRNA

NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018

G

NADH:ubiquinone oxidoreductase subunit B10

increases expression

folpet results in increased expression of NDUFB10 mRNA

NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442

G

NADH:ubiquinone oxidoreductase subunit B5

increases expression

folpet results in increased expression of NDUFB5 mRNA

NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589

G

NADH:ubiquinone oxidoreductase subunit B6

increases expression

folpet results in increased expression of NDUFB6 mRNA

NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181

G

NADH:ubiquinone oxidoreductase core subunit S7

decreases expression

folpet results in decreased expression of NDUFS7 mRNA

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

NADH:ubiquinone oxidoreductase subunit V3

decreases expression

folpet results in decreased expression of NDUFV3 mRNA

NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

G

neuroepithelial cell transforming 1

increases expression

folpet results in increased expression of NET1 mRNA

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

nuclear factor, interleukin 3 regulated

decreases expression

folpet results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor beta

increases expression

folpet results in increased expression of NFKBIB mRNA

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

NHERF family PDZ scaffold protein 1

increases expression

folpet results in increased expression of NHERF1 mRNA

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression

folpet results in decreased expression of NME1 mRNA

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

notch receptor 1

decreases expression

folpet results in decreased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

NAD(P)H quinone dehydrogenase 1

increases expression

folpet results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group I, member 2

increases expression

folpet results in increased expression of NR1I2 mRNA

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases expression

folpet results in increased expression of NR1I3 mRNA

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 3, group C, member 1

decreases expression

folpet results in decreased expression of NR3C1 mRNA

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

nebulin-related anchoring protein

increases expression

folpet results in increased expression of NRAP mRNA

NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693

G

nucleobindin 2

decreases expression

folpet results in decreased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

NudC domain containing 3

decreases expression

folpet results in decreased expression of NUDCD3 mRNA

NCBI chr14:80,976,330...81,059,183
Ensembl chr14:80,976,328...81,058,962

G

nucleoporin 37

decreases expression

folpet results in decreased expression of NUP37 mRNA

NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616

G

nucleoporin 62

decreases expression

folpet results in decreased expression of NUP62 mRNA

NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174

G

nucleoporin 85

decreases expression

folpet results in decreased expression of NUP85 mRNA

NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043

G

opsin 3

increases expression

folpet results in increased expression of OPN3 mRNA

NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847

G

oxidative stress induced growth inhibitor 1

increases expression

folpet results in increased expression of OSGIN1 mRNA

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

3-oxoacid CoA transferase 1

increases expression

folpet results in increased expression of OXCT1 mRNA

NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714

G

prolyl 3-hydroxylase 3

decreases expression

folpet results in decreased expression of P3H3 mRNA

NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035

G

prolyl 4-hydroxylase subunit beta

increases expression

folpet results in increased expression of P4HB mRNA

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

p21 (RAC1) activated kinase 4

increases expression

folpet results in increased expression of PAK4 mRNA

NCBI chr 1:83,849,904...83,889,188
Ensembl chr 1:83,849,904...83,859,413

G

pantothenate kinase 2

decreases expression

folpet results in decreased expression of PANK2 mRNA

NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320

G

Pannexin 1

decreases expression

folpet results in decreased expression of PANX1 mRNA

NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774

G

Parkinsonism associated deglycase

decreases activity

folpet results in decreased activity of PARK7 protein

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

G

presenilin associated, rhomboid-like

increases expression

folpet results in increased expression of PARL mRNA

NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506

G

polysaccharide biosynthesis domain containing 1

increases expression

folpet results in increased expression of PBDC1 mRNA

NCBI chr X:70,154,106...70,197,827
Ensembl chr X:70,154,106...70,184,552

G

propionyl-CoA carboxylase subunit beta

increases expression

folpet results in increased expression of PCCB mRNA

NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234

G

protein disulfide isomerase family A, member 5

decreases expression

folpet results in decreased expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

PDZ and LIM domain 1

increases expression

folpet results in increased expression of PDLIM1 mRNA

NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076

G

phosphofructokinase, liver type

increases expression

folpet results in increased expression of PFKL mRNA

NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315

G

profilin 1

increases expression

folpet results in increased expression of PFN1 mRNA

NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631

G

phosphoglucomutase 2

increases expression

folpet results in increased expression of PGM2 mRNA

NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967

G

progesterone receptor membrane component 1

increases expression

folpet results in increased expression of PGRMC1 mRNA

NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682

G

phosphohistidine phosphatase 1

increases expression

folpet results in increased expression of PHPT1 mRNA

NCBI chr 3:8,392,926...8,394,325

G

phosphatidylinositol glycan anchor biosynthesis, class F

decreases expression

folpet results in decreased expression of PIGF mRNA

NCBI chr 6:7,589,584...7,617,719
Ensembl chr 6:7,589,570...7,639,675

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

increases expression

folpet results in increased expression of PIK3C2B mRNA

NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

decreases expression

folpet results in decreased expression of PIK3CG mRNA

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

G

plasminogen activator, urokinase

decreases expression

folpet results in decreased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

polo-like kinase 3

increases expression

folpet results in increased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

polynucleotide kinase 3'-phosphatase

increases expression

folpet results in increased expression of PNKP mRNA

NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920

G

purine nucleoside phosphorylase

decreases expression

folpet results in decreased expression of PNP2 mRNA

NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986

G

DNA polymerase delta 4, accessory subunit

increases expression

folpet results in increased expression of POLD4 mRNA

NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401

G

RNA polymerase I and III subunit D

increases expression

folpet results in increased expression of POLR1D mRNA

NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624

G

RNA polymerase I subunit H

decreases expression

folpet results in decreased expression of POLR1H mRNA

NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854

G

RNA polymerase II subunit C

decreases expression

folpet results in decreased expression of POLR2C mRNA

NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945

G

RNA polymerase III subunit B

decreases expression

folpet results in decreased expression of POLR3B mRNA

NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598

G

cytochrome p450 oxidoreductase

increases expression

folpet results in increased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

peroxisome proliferator activated receptor alpha

increases expression

folpet results in increased expression of PPARA mRNA

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

PPARG coactivator 1 alpha

decreases expression

folpet results in decreased expression of PPARGC1A mRNA

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

peptidylprolyl isomerase B

decreases expression

folpet results in decreased expression of PPIB mRNA

NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428

G

protein phosphatase 1, regulatory subunit 27

increases expression

folpet results in increased expression of PPP1R27 mRNA

NCBI chr10:105,828,364...105,829,533
Ensembl chr10:105,828,364...105,829,533

G

protein regulator of cytokinesis 1

decreases expression

folpet results in decreased expression of PRC1 mRNA

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

peroxiredoxin 1

increases expression

folpet results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

increases expression

folpet results in increased expression of PRDX3 mRNA

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

protein kinase AMP-activated catalytic subunit alpha 2

increases expression

folpet results in increased expression of PRKAA2 mRNA

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

protein kinase AMP-activated non-catalytic subunit beta 1

decreases expression

folpet results in decreased expression of PRKAB1 mRNA

NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661

G

protein kinase AMP-activated non-catalytic subunit gamma 2

decreases expression

folpet results in decreased expression of PRKAG2 mRNA

NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142

G

protein kinase C, alpha

increases expression

folpet results in increased expression of PRKCA mRNA

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

G

protein kinase C, delta

increases expression

folpet results in increased expression of PRKCD mRNA

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

G

protein kinase C, eta

decreases expression

folpet results in decreased expression of PRKCH mRNA

NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654

G

protein kinase cGMP-dependent 1

decreases expression

folpet results in decreased expression of PRKG1 mRNA

NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080

G

serine protease 8

decreases expression

folpet results in decreased expression of PRSS8 mRNA

NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815

G

presenilin 1

decreases expression

folpet results in decreased expression of PSEN1 mRNA

NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650

G

proteasome 26S subunit, ATPase 4

increases expression

folpet results in increased expression of PSMC4 mRNA

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, non-ATPase 12

decreases expression

folpet results in decreased expression of PSMD12 mRNA

NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287

G

proteasome 26S subunit, non-ATPase 14

increases expression

folpet results in increased expression of PSMD14 mRNA

NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076

G

proteasome 26S subunit, non-ATPase 8

increases expression

folpet results in increased expression of PSMD8 mRNA

NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209

G

proteasome activator subunit 2

increases expression

folpet results in increased expression of PSME2 mRNA

NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946

G

proteasome assembly chaperone 1

increases expression

folpet results in increased expression of PSMG1 mRNA

NCBI chr11:35,276,080...35,285,541
Ensembl chr11:35,276,011...35,285,622

G

phosphoserine phosphatase

increases expression

folpet results in increased expression of PSPH mRNA

NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074

G

prostaglandin E receptor 4

increases expression

folpet results in increased expression of PTGER4 mRNA

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

G

protein tyrosine kinase 2 beta

decreases expression

folpet results in decreased expression of PTK2B mRNA

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

G

protein tyrosine phosphatase, receptor type, C

decreases expression

folpet results in decreased expression of PTPRC mRNA

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

G

protein tyrosine phosphatase, receptor type, K

decreases expression

folpet results in decreased expression of PTPRK mRNA

NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605

G

PWP1 homolog, endonuclein

decreases expression

folpet results in decreased expression of PWP1 mRNA

NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731

G

quinoid dihydropteridine reductase

increases expression

folpet results in increased expression of QDPR mRNA

NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854

G

RAB11a, member RAS oncogene family

increases expression

folpet results in increased expression of RAB11A mRNA

NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525

G

RAB31, member RAS oncogene family

increases expression

folpet results in increased expression of RAB31 mRNA

NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253

G

Rac family small GTPase 1

increases expression

folpet results in increased expression of RAC1 mRNA

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

G

Rap1 GTPase-activating protein

decreases expression

folpet results in decreased expression of RAP1GAP mRNA

NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253

G

Rap guanine nucleotide exchange factor 2

increases expression

folpet results in increased expression of RAPGEF2 mRNA

NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247

G

RB transcriptional corepressor 1

increases expression

folpet results in increased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RNA binding motif protein 15B

decreases expression

folpet results in decreased expression of RBM15B mRNA

NCBI chr 8:107,543,613...107,546,678
Ensembl chr 8:107,525,898...107,551,696

G

regenerating family member 1 alpha

decreases expression

folpet results in decreased expression of REG1 mRNA

NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570

G

RELA proto-oncogene, NF-kB subunit

decreases expression

folpet results in decreased expression of RELA mRNA

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

decreases expression

folpet results in decreased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

decreases expression

folpet results in decreased expression of RFNG mRNA

NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345

G

regulator of G-protein signaling 2

decreases expression

folpet results in decreased expression of RGS2 mRNA

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

Ras homolog, mTORC1 binding

increases expression

folpet results in increased expression of RHEB mRNA

NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160

G

regulating synaptic membrane exocytosis 1

decreases expression

folpet results in decreased expression of RIMS1 mRNA

NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631

G

ribonuclease H2, subunit A

decreases expression

folpet results in decreased expression of RNASEH2A mRNA

NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041

G

ring finger protein 125

decreases expression

folpet results in decreased expression of RNF125 mRNA

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

G

replication protein A1

decreases expression

folpet results in decreased expression of RPA1 mRNA

NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949

G

ribosomal protein lateral stalk subunit P0

increases expression

folpet results in increased expression of RPLP0 mRNA

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

ribophorin I

decreases expression

folpet results in decreased expression of RPN1 mRNA

NCBI chr 4:120,543,667...120,565,069
Ensembl chr 4:120,543,667...120,565,069

G

ribosomal protein S6 kinase A1

decreases expression

folpet results in decreased expression of RPS6KA1 mRNA

NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272

G

Ras-related GTP binding A

decreases expression

folpet results in decreased expression of RRAGA mRNA

NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510

G

ribosome biogenesis regulator 1 homolog

decreases expression

folpet results in decreased expression of RRS1 mRNA

NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140

G

RT1 class II, locus Ba

decreases expression

folpet results in decreased expression of H2-AA mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

S100 calcium binding protein A11

increases expression

folpet results in increased expression of S100A11 mRNA

NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044

G

S100 calcium binding protein A6

increases expression

folpet results in increased expression of S100A6 mRNA

NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180

G

secretogranin II

decreases expression

folpet results in decreased expression of SCG2 mRNA

NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097

G

sterol carrier protein 2

increases expression

folpet results in increased expression of SCP2 mRNA

NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287

G

SEL1L adaptor subunit of SYVN1 ubiquitin ligase

decreases expression

folpet results in decreased expression of SEL1L mRNA

NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648

G

selenoprotein N

decreases expression

folpet results in decreased expression of SEPN1 mRNA

NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059

G

SUMO specific peptidase 6

decreases expression

folpet results in decreased expression of SENP6 mRNA

NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170

G

septin 5

increases expression

folpet results in increased expression of SEPTIN5 mRNA

NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393

G

serpin family G member 1

decreases expression

folpet results in decreased expression of SERPING1 mRNA

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

G

sestrin 1

decreases expression

folpet results in decreased expression of SESN1 mRNA

NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697

G

SH3 domain containing GRB2 like 2, endophilin A1

increases expression

folpet results in increased expression of SH3GL2 mRNA

NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843

G

S-phase kinase-associated protein 1

increases expression

folpet results in increased expression of SKP1 mRNA

NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388

G

solute carrier family 11 member 2

increases expression

folpet results in increased expression of SLC11A2 mRNA

NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145

G

solute carrier family 16 member 3

increases expression

folpet results in increased expression of SLC16A3 mRNA

NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 1 member 2

decreases expression

folpet results in decreased expression of SLC1A2 mRNA

NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498

G

solute carrier family 1 member 3

decreases expression

folpet results in decreased expression of SLC1A3 mRNA

NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 27 member 1

decreases expression

folpet results in decreased expression of SLC27A1 mRNA

NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 27 member 2

decreases expression

folpet results in decreased expression of SLC27A2 mRNA

NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 30 member 5

decreases expression

folpet results in decreased expression of SLC30A5 mRNA

NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934

G

solute carrier family 35 member A3

decreases expression

folpet results in decreased expression of SLC35A3 mRNA

NCBI chr 2:204,620,103...204,659,319
Ensembl chr 2:204,579,174...204,659,319

G

solute carrier family 47 member 1

increases expression

folpet results in increased expression of SLC47A1 mRNA

NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637

G

solute carrier family 51 member A

increases expression

folpet results in increased expression of SLC51A mRNA

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 6 member 8

increases expression

folpet results in increased expression of SLC6A8 mRNA

NCBI chr X:151,384,675...151,393,979
Ensembl chr X:151,384,675...151,393,979

G

solute carrier family 7 member 11

increases expression

folpet results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

solute carrier organic anion transporter family, member 2b1

decreases expression

folpet results in decreased expression of SLCO2B1 mRNA

NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353

G

SMAD family member 1

decreases expression

folpet results in decreased expression of SMAD1 mRNA

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

decreases expression

folpet results in decreased expression of SMARCC1 mRNA

NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720

G

SWI/SNF related BAF chromatin remodeling complex subunit D2

decreases expression

folpet results in decreased expression of SMARCD2 mRNA

NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341

G

small nuclear ribonucleoprotein polypeptides B and B1

increases expression

folpet results in increased expression of SNRPB mRNA

NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339

G

small nuclear ribonucleoprotein polypeptide E

decreases expression

folpet results in decreased expression of SNRPE mRNA

NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310

G

sorting nexin 7

increases expression

folpet results in increased expression of SNX7 mRNA

NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763

G

suppressor of cytokine signaling 2

decreases expression

folpet results in decreased expression of SOCS2 mRNA

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

G

superoxide dismutase 1

increases expression

folpet results in increased expression of SOD1 mRNA

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

signal peptidase complex subunit 2

increases expression

folpet results in increased expression of SPCS2 mRNA

NCBI chr 1:154,163,724...154,183,152
Ensembl chr 1:154,163,724...154,183,186

G

signal peptidase complex subunit 3

decreases expression

folpet results in decreased expression of SPCS3 mRNA

NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746

G

SAM pointed domain containing ets transcription factor

decreases expression

folpet results in decreased expression of SPDEF mRNA

NCBI chr20:5,771,440...5,785,893
Ensembl chr20:5,771,441...5,785,893

G

squalene epoxidase

decreases expression

folpet results in decreased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sulfide quinone oxidoreductase

increases expression

folpet results in increased expression of SQOR mRNA

NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778

G

steroid 5 alpha-reductase 1

increases expression

folpet results in increased expression of SRD5A1 mRNA

NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461

G

serrate, RNA effector molecule

decreases expression

folpet results in decreased expression of SRRT mRNA

NCBI chr12:19,392,578...19,406,098
Ensembl chr12:19,392,625...19,406,095

G

serine and arginine rich splicing factor 1

decreases expression

folpet results in decreased expression of SRSF1 mRNA

NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336

G

sulfiredoxin 1

increases expression

folpet results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

ST14 transmembrane serine protease matriptase

increases expression

folpet results in increased expression of ST14 mRNA

NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

decreases expression

folpet results in decreased expression of ST3GAL2 mRNA

NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869

G

spermatid perinuclear RNA binding protein

increases expression

folpet results in increased expression of STRBP mRNA

NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949

G

STIP1 homology and U-box containing protein 1

increases expression

folpet results in increased expression of STUB1 mRNA

NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046

G

syntaxin binding protein 2

increases expression

folpet results in increased expression of STXBP2 mRNA

NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458

G

sulfotransferase family 1B member 1

increases expression

folpet results in increased expression of SULT1B1 mRNA

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

TGF-beta activated kinase 1/MAP3K7 binding protein 2

decreases expression

folpet results in decreased expression of TAB2 mRNA

NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756

G

transaldolase 1

increases expression

folpet results in increased expression of TALDO1 mRNA

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974

G

Tax1 binding protein 3

increases expression

folpet results in increased expression of TAX1BP3 mRNA

NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363

G

T-box transcription factor 2

decreases expression

folpet results in decreased expression of TBX2 mRNA

NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529

G

transcription factor 4

decreases expression

folpet results in decreased expression of TCF4 mRNA

NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425

G

t-complex 1

increases expression

folpet results in increased expression of TCP1 mRNA

NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839

G

testis associated actin remodelling kinase 1

decreases expression

folpet results in decreased expression of TESK1 mRNA

NCBI chr 5:57,691,922...57,697,698
Ensembl chr 5:57,691,969...57,697,698

G

thrombomodulin

decreases expression

folpet results in decreased expression of THBD mRNA

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

G

Thy-1 cell surface antigen

decreases expression

folpet results in decreased expression of THY1 mRNA

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

G

TIAM Rac1 associated GEF 1

decreases expression

folpet results in decreased expression of TIAM1 mRNA

NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901

G

TP53 induced glycolysis regulatory phosphatase

increases expression

folpet results in increased expression of TIGAR mRNA

NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029

G

translocase of inner mitochondrial membrane 17A

increases expression

folpet results in increased expression of TIMM17A mRNA

NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655

G

tight junction protein 1

decreases expression

folpet results in decreased expression of TJP1 mRNA

NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432

G

transmembrane 7 superfamily member 3

decreases expression

folpet results in decreased expression of TM7SF3 mRNA

NCBI chr 4:179,518,127...179,550,154
Ensembl chr 4:179,518,130...179,550,154

G

transmembrane 9 superfamily member 3

decreases expression

folpet results in decreased expression of TM9SF3 mRNA

NCBI chr 1:240,032,060...240,085,125
Ensembl chr 1:240,035,003...240,084,776

G

transmembrane channel-like 7

increases expression

folpet results in increased expression of TMC7 mRNA

NCBI chr 1:172,853,531...172,905,796
Ensembl chr 1:172,854,658...172,905,824

G

transmembrane protein 109

decreases expression

folpet results in decreased expression of TMEM109 mRNA

NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215

G

transmembrane protein 97

decreases expression

folpet results in decreased expression of TMEM97 mRNA

NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730

G

TNFAIP3 interacting protein 1

increases expression

folpet results in increased expression of TNIP1 mRNA

NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625

G

torsin family 1, member A

increases expression

folpet results in increased expression of TOR1A mRNA

NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691

G

tumor protein p53 inducible nuclear protein 2

decreases expression

folpet results in decreased expression of TRP53INP2 mRNA

NCBI chr 3:143,881,427...143,890,104
Ensembl chr 3:143,882,021...143,890,097

G

triosephosphate isomerase 1

increases expression

folpet results in increased expression of TPI1 mRNA

NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541

G

TNF receptor-associated protein 1

decreases expression

folpet results in decreased expression of TRAP1 mRNA

NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981

G

tribbles pseudokinase 1

increases expression

folpet results in increased expression of TRIB1 mRNA

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

G

tripartite motif-containing 28

decreases expression

folpet results in decreased expression of TRIM28 mRNA

NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380

G

TSC complex subunit 2

decreases expression

folpet results in decreased expression of TSC2 mRNA

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

G

TSC22 domain family, member 3

increases expression

folpet results in increased expression of TSC22D3 mRNA

NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861

G

tsukushi, small leucine rich proteoglycan

increases expression

folpet results in increased expression of TSKU mRNA

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

G

tetraspanin 6

decreases expression

folpet results in decreased expression of TSPAN6 mRNA

NCBI chr X:97,092,394...97,099,659
Ensembl chr X:97,092,388...97,099,309

G

tetratricopeptide repeat domain 17

increases expression

folpet results in increased expression of TTC17 mRNA

NCBI chr 3:80,263,488...80,374,137
Ensembl chr 3:80,263,495...80,373,812

G

tubulin, alpha 4A

increases expression

folpet results in increased expression of TUBA4A mRNA

NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918

G

tubulin, beta 2A class IIa

increases expression

folpet results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

tubulin, beta 6 class V

decreases expression

folpet results in decreased expression of TUBB6 mRNA

NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418

G

thioredoxin reductase 1

increases expression

folpet results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thioredoxin reductase 2

increases expression

folpet results in increased expression of TXNRD2 mRNA

NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156

G

UDP-glucose 6-dehydrogenase

increases expression

folpet results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase family 1 member A5

increases expression

folpet results in increased expression of UGT1A5 mRNA

NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

increases expression

folpet results in increased expression of UQCRFS1 mRNA

NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479

G

UTP4 small subunit processome component

decreases expression

folpet results in decreased expression of UTP4 mRNA

NCBI chr19:34,790,962...34,820,558
Ensembl chr19:34,792,457...34,820,550

G

vesicle amine transport 1

increases expression

folpet results in increased expression of VAT1 mRNA

NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224

G

voltage-dependent anion channel 1

increases expression

folpet results in increased expression of VDAC1 mRNA

NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640

G

vascular endothelial growth factor A

decreases expression

folpet results in decreased expression of VEGFA mRNA

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vimentin

decreases expression

folpet results in decreased expression of VIM mRNA

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vacuolar protein sorting 4 homolog A

increases expression

folpet results in increased expression of VPS4A mRNA

NCBI chr19:34,934,999...34,948,888
Ensembl chr19:34,934,961...34,948,887

G

WD repeat domain 3

decreases expression

folpet results in decreased expression of WDR3 mRNA

NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432

G

WD and tetratricopeptide repeats 1

decreases expression

folpet results in decreased expression of WDTC1 mRNA

NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408

G

WAS/WASL interacting protein family, member 2

increases expression

folpet results in increased expression of WIPF2 mRNA

NCBI chr10:83,821,067...83,861,634
Ensembl chr10:83,821,068...83,857,028

G

X-box binding protein 1

decreases expression

folpet results in decreased expression of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

exportin 7

increases expression

folpet results in increased expression of XPO7 mRNA

NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050

G

tyrosyl-tRNA synthetase 2

decreases expression

folpet results in decreased expression of YARS2 mRNA

NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125

G

YKT6 v-SNARE homolog

increases expression

folpet results in increased expression of YKT6 mRNA

NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385

G

YTH N6-methyladenosine RNA binding protein F1

decreases expression

folpet results in decreased expression of YTHDF1 mRNA

NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

increases expression

folpet results in increased expression of YWHAZ mRNA

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

G

Z-DNA binding protein 1

decreases expression

folpet results in decreased expression of ZBP1 mRNA

NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870

G

zinc finger protein 395

decreases expression

folpet results in decreased expression of ZFP395 mRNA

NCBI chr15:39,581,603...39,621,911
Ensembl chr15:39,608,080...39,619,950

G

zymogen granule protein 16

decreases expression

folpet results in decreased expression of ZG16 mRNA

NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079

G

zinc finger, HIT-type containing 6

increases expression

folpet results in increased expression of ZNHIT6 mRNA

NCBI chr 2:234,486,686...234,517,952
Ensembl chr 2:234,486,704...234,517,960

phosmet

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

decreases activity

Phosmet metabolite results in decreased activity of ACHE protein; Phosmet results in decreased activity of ACHE protein

PMID:30625376 PMID:33720374

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

interleukin 13

increases expression

Phosmet results in increased expression of IL13 mRNA

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

increases expression

Phosmet results in increased expression of IL17A mRNA

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

tumor necrosis factor

increases secretion

Phosmet results in increased secretion of TNF mRNA; Phosmet results in increased secretion of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

affects activity

Phosmet metabolite affects the activity of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

phthalimide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tumor necrosis factor

decreases expression
increases expression

phthalimide analog results in decreased expression of TNF protein
phthalimide analog results in increased expression of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

pomalidomide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

bromodomain containing 4

multiple interactions

pomalidomide inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]

NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539

G

caspase 3

multiple interactions

[afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP8 protein

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

C-C motif chemokine ligand 2

increases secretion

pomalidomide results in increased secretion of CCL2 protein

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

CCAAT/enhancer binding protein alpha

increases expression

pomalidomide results in increased expression of CEBPA mRNA

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein delta

increases expression

pomalidomide results in increased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

CCAAT/enhancer binding protein epsilon

increases expression

pomalidomide results in increased expression of CEBPE mRNA

NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814

G

cereblon

multiple interactions
affects binding
increases response to substance

[pomalidomide co-treated with Dexamethasone co-treated with afuresertib] results in increased expression of CRBN protein; [pomalidomide co-treated with Dexamethasone] results in increased expression of CRBN protein; pomalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein]
pomalidomide binds to [SALL4 protein binds to CRBN protein]
CRBN results in increased susceptibility to pomalidomide

PMID:25043012 PMID:26186254 PMID:29928335 PMID:30067223

NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938

G

colony stimulating factor 2

decreases secretion

pomalidomide results in decreased secretion of CSF2 protein

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

increases secretion

pomalidomide results in increased secretion of CSF3 protein

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

cytochrome P450, family 2, subfamily C, polypeptide 6

increases oxidation

CYP2C19 protein results in increased oxidation of pomalidomide

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily j, polypeptide 4

increases oxidation

CYP2J2 protein results in increased oxidation of pomalidomide

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases oxidation

CYP3A4 protein results in increased oxidation of pomalidomide

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

DTW domain containing 1

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of DTWD1 protein

NCBI chr 3:113,392,402...113,409,322
Ensembl chr 3:113,392,457...113,408,105

G

eukaryotic translation initiation factor 4E binding protein 1

multiple interactions

[pomalidomide co-treated with Dexamethasone] results in decreased phosphorylation of EIF4EBP1 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased phosphorylation of EIF4EBP1 protein]

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

family with sequence similarity 83, member F

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of FAM83F protein

NCBI chr 7:112,211,164...112,240,454
Ensembl chr 7:112,211,164...112,240,452

G

Fibroblast growth factor receptor 1

decreases expression

pomalidomide results in decreased expression of FGFR1 mRNA

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibroblast growth factor receptor 3

affects expression

pomalidomide affects the expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

forkhead box O1

multiple interactions

[pomalidomide co-treated with Dexamethasone] affects the phosphorylation of FOXO1 protein; afuresertib affects the reaction [[pomalidomide co-treated with Dexamethasone] affects the phosphorylation of FOXO1 protein]

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

GATA binding protein 1

decreases expression

pomalidomide results in decreased expression of GATA1 mRNA; pomalidomide results in decreased expression of GATA1 protein

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

G

GATA binding protein 2

decreases expression

pomalidomide results in decreased expression of GATA2 mRNA

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

G

growth factor independent 1 transcriptional repressor

increases expression

pomalidomide results in increased expression of GFI1 mRNA

NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814

G

growth factor independent 1B transcriptional repressor

decreases expression

pomalidomide results in decreased expression of GFI1B mRNA

NCBI chr 3:11,940,232...11,952,989
Ensembl chr 3:11,940,233...11,952,942

G

inhibitor of DNA binding 1

increases expression

pomalidomide results in increased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 2

increases expression

pomalidomide results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

IKAROS family zinc finger 1

multiple interactions

[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF1 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF1 protein]

NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416

G

IKAROS family zinc finger 3

multiple interactions

[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF3 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF3 protein]

NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591

G

interleukin 10

increases secretion

pomalidomide results in increased secretion of IL10 protein

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 13

decreases secretion

pomalidomide results in decreased secretion of IL13 protein

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 2

multiple interactions

Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 5

decreases secretion

pomalidomide results in decreased secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interferon regulatory factor 4

multiple interactions

[pomalidomide co-treated with Dexamethasone co-treated with afuresertib] results in decreased expression of IRF4 protein; [pomalidomide co-treated with Dexamethasone] results in decreased expression of IRF4 protein

NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases expression

pomalidomide results in decreased expression of JUND mRNA

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

KLF transcription factor 1

decreases expression

pomalidomide results in decreased expression of KLF1 mRNA

NCBI chr19:23,250,627...23,253,802
Ensembl chr19:23,250,631...23,253,758

G

LIM domain only 2

decreases expression

pomalidomide results in decreased expression of LMO2 mRNA

NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953

G

Meis homeobox 2

multiple interactions

pomalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein]

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

nuclear factor, erythroid 2

decreases expression

pomalidomide results in decreased expression of NFE2 mRNA

NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108

G

protein kinase C, theta

multiple interactions

pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein]

NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704

G

RAB28, member RAS oncogene family

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of RAB28 protein

NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967

G

spalt-like transcription factor 4

affects binding
multiple interactions

pomalidomide binds to [SALL4 protein binds to CRBN protein]
pomalidomide results in increased degradation of and results in decreased expression of SALL4 protein

NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822

G

Spi-1 proto-oncogene

increases expression
decreases expression

pomalidomide results in increased expression of SPI1 mRNA
pomalidomide results in decreased expression of SPI1 protein

PMID:15292067 PMID:16373662

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

G

WIZ zinc finger

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of WIZ protein

NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490

G

zinc finger and BTB domain containing 39

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of ZBTB39 protein

NCBI chr 7:63,576,998...63,584,549
Ensembl chr 7:63,576,917...63,589,210

G

zinc finger protein 653

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of ZNF653 protein

NCBI chr 8:20,586,607...20,605,439
Ensembl chr 8:20,586,563...20,604,864

G

zinc finger protein 91

multiple interactions

pomalidomide results in increased degradation of and results in decreased expression of ZFP91 protein

NCBI chr 1:209,891,344...209,928,890
Ensembl chr 1:209,891,344...209,927,762

tetramethrin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

multiple interactions
decreases expression

tetramethrin results in decreased activity of [Dihydrotestosterone results in increased activity of AR protein]
tetramethrin results in decreased expression of AR mRNA

PMID:12711008 PMID:16621434

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

BRCA1, DNA repair associated

affects binding

tetramethrin binds to BRCA1 protein

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

carboxylesterase 2H

multiple interactions
increases metabolic processing

CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein]
CES2 protein results in increased metabolism of tetramethrin

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases metabolic processing

CYP3A4 protein results in increased metabolism of tetramethrin

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

estrogen receptor 1

decreases expression

tetramethrin results in decreased expression of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

increases expression

tetramethrin results in increased expression of ESR2 protein

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

folate hydrolase 1

decreases expression

tetramethrin results in decreased expression of FOLH1 mRNA

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

insulin-like growth factor 1

multiple interactions

tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium]

PMID:1550224 PMID:2460452 PMID:2539779

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 2

multiple interactions

tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium]

PMID:2442157 PMID:2539779

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

G

potassium voltage-gated channel subfamily H member 2

decreases activity

tetramethrin results in decreased activity of KCNH2 protein

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

kallikrein 1-related peptidase C10

increases expression

tetramethrin results in increased expression of KLK3 mRNA

NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052

G

NK3 homeobox 1

decreases expression

tetramethrin results in decreased expression of NKX3-1 mRNA

NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein]

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

[Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin] results in increased activity of NR3C1 protein; [tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

S100 calcium binding protein G

decreases expression
multiple interactions

tetramethrin results in decreased expression of S100G mRNA
tetramethrin inhibits the reaction [Estradiol results in increased expression of S100G mRNA]

NCBI chr X:31,705,853...31,708,422
Ensembl chr X:31,705,866...31,708,433

G

sex hormone binding globulin

affects binding

tetramethrin binds to SHBG protein

NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057

thalidomide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate aminotransferase

decreases expression

Thalidomide results in decreased expression of AADAT mRNA

NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332

G

ATP binding cassette subfamily A member 1

increases response to substance

ABCA1 gene SNP results in increased susceptibility to Thalidomide

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily B member 1A

decreases expression
decreases activity

Thalidomide results in decreased expression of ABCB1 mRNA; Thalidomide results in decreased expression of ABCB1 protein
Thalidomide results in decreased activity of ABCB1 protein

PMID:15920492 PMID:19840843

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP-binding cassette, sub-family B member 1B

increases expression
increases activity

Thalidomide results in increased expression of ABCB1B protein
Thalidomide results in increased activity of ABCB1B protein

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

acid phosphatase 5, tartrate resistant

multiple interactions

[Thalidomide co-treated with Dexamethasone] results in decreased expression of ACP5 protein

NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929

G

actin alpha 2, smooth muscle

multiple interactions
decreases expression

[Thalidomide co-treated with Dimethylnitrosamine] results in decreased expression of ACTA2 protein; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Thalidomide results in decreased expression of ACTA2 protein

PMID:16604421 PMID:16943688 PMID:17030452 PMID:17174718

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actinin alpha 2

decreases expression

Thalidomide results in decreased expression of ACTN2 mRNA

PMID:26006729 PMID:26217789

NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622

G

actin related protein 6

decreases expression

Thalidomide results in decreased expression of ACTR6 mRNA

NCBI chr 7:24,150,250...24,171,057
Ensembl chr 7:24,150,250...24,171,067

G

adenylosuccinate synthase 1

decreases expression

Thalidomide results in decreased expression of ADSS1 mRNA

NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998

G

ALF transcription elongation factor 2

decreases expression

Thalidomide results in decreased expression of AFF2 mRNA

NCBI chr X:147,928,130...148,432,484
Ensembl chr X:147,928,407...148,429,995

G

AKT serine/threonine kinase 1

decreases phosphorylation
increases phosphorylation
decreases activity

Thalidomide analog results in decreased phosphorylation of AKT1 protein
Thalidomide analog results in increased phosphorylation of AKT1 protein
Thalidomide results in decreased activity of AKT1 protein

PMID:15067094 PMID:15858615

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aldehyde dehydrogenase 1 family, member A2

decreases expression

Thalidomide results in decreased expression of ALDH1A2 mRNA

NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107

G

alkaline phosphatase, intestinal

increases expression

Thalidomide results in increased expression of ALPI mRNA

NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877

G

alpha-methylacyl-CoA racemase

decreases expression

Thalidomide results in decreased expression of AMACR mRNA

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

angiopoietin 2

affects expression

Thalidomide affects the expression of ANGPT2 mRNA

NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804

G

ankyrin repeat domain 37

decreases expression

Thalidomide results in decreased expression of ANKRD37 mRNA

NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963

G

annexin A2

decreases expression

Thalidomide results in decreased expression of ANXA2 mRNA; Thalidomide results in decreased expression of ANXA2 protein

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

APAF1 interacting protein

decreases expression

Thalidomide results in decreased expression of APIP mRNA

NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340

G

apelin

decreases expression

Thalidomide results in decreased expression of APLN mRNA

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

G

aquaporin 4

increases expression

Thalidomide results in increased expression of AQP4 mRNA

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

aquaporin 5

increases expression

Thalidomide results in increased expression of AQP5 mRNA

NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209

G

Rho GDP dissociation inhibitor alpha

increases expression

Thalidomide results in increased expression of ARHGDIA mRNA

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

actin related protein 2/3 complex, subunit 4

decreases expression

Thalidomide results in decreased expression of ARPC4 mRNA

NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785

G

aristaless related homeobox

increases expression

Thalidomide results in increased expression of ARX mRNA

NCBI chr X:58,016,233...58,028,149
Ensembl chr X:58,016,233...58,028,142

G

adipocyte-related X-chromosome expressed sequence 1

decreases expression

Thalidomide results in decreased expression of ARXES1 mRNA

NCBI chr X:98,950,530...98,952,049
Ensembl chr X:98,950,528...98,952,045

G

ankyrin repeat and SOCS box-containing 12

decreases expression

Thalidomide results in decreased expression of ASB12 mRNA

NCBI chr X:60,328,325...60,478,031
Ensembl chr X:60,328,328...60,415,619

G

activating transcription factor 3

increases expression

Thalidomide analog results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

aurora kinase A

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

Thalidomide results in increased expression of BAX mRNA
HDAC6 protein inhibits the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of BAX protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of BAX protein]]; Thalidomide inhibits the reaction [Paraquat results in increased expression of BAX protein]

PMID:18291259 PMID:33015978

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

B-cell receptor-associated protein 29

decreases expression

Thalidomide results in decreased expression of BCAP29 mRNA

NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

[oblimersen co-treated with Thalidomide co-treated with Dexamethasone] results in decreased expression of BCL2 mRNA; [oblimersen co-treated with Thalidomide co-treated with Dexamethasone] results in decreased expression of BCL2 protein
Thalidomide results in decreased expression of BCL2 protein
HDAC6 protein inhibits the reaction [Thalidomide inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]]; Thalidomide inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]

PMID:15867202 PMID:15982930 PMID:33015978

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

Thalidomide results in decreased expression of BCL2L1 protein

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

bradykinin receptor B1

multiple interactions

Thalidomide inhibits the reaction [bradykinin, des-Arg(9)- results in increased expression of BDKRB1 protein]

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

beclin 1

multiple interactions

Thalidomide promotes the reaction [temozolomide results in increased expression of BECN1 protein]

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

BCL2 interacting protein like

increases expression

Thalidomide results in increased expression of BNIPL mRNA

NCBI chr 2:182,818,593...182,830,421
Ensembl chr 2:182,818,595...182,828,588

G

biorientation of chromosomes in cell division 1

decreases expression

Thalidomide results in decreased expression of BOD1 mRNA

NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787

G

bone marrow stromal cell antigen 2

decreases expression

Thalidomide results in decreased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

BUB1 mitotic checkpoint serine/threonine kinase B

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA

NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547

G

complement C3

decreases expression

Thalidomide results in decreased expression of C3 protein

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

calcium voltage-gated channel subunit alpha1 C

decreases expression

Thalidomide results in decreased expression of CACNA1C mRNA

PMID:26006729 PMID:26217789

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

G

calcium voltage-gated channel auxiliary subunit beta 4

decreases expression

Thalidomide results in decreased expression of CACNB4 mRNA

NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944

G

calbindin 1

decreases expression

Thalidomide results in decreased expression of CALB1 mRNA

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

G

caspase 3

decreases activity
increases activity
increases expression

Thalidomide results in decreased activity of CASP3 protein
Thalidomide results in increased activity of CASP3 protein
Thalidomide results in increased expression of CASP3 mRNA

PMID:14682394 PMID:15067094 PMID:18291259

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

increases cleavage
decreases expression

Thalidomide analog results in increased cleavage of CASP8 protein
Thalidomide results in decreased expression of CASP8 mRNA

PMID:15858615 PMID:26217789

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

decreases activity

Thalidomide results in decreased activity of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cytosolic arginine sensor for mTORC1 subunit 1

decreases expression

Thalidomide results in decreased expression of CASTOR1 mRNA

NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548

G

catalase

multiple interactions

CAT protein inhibits the reaction [Thalidomide results in decreased activity of MYB protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 1

decreases expression

Thalidomide results in decreased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

coiled-coil domain containing 141

decreases expression

Thalidomide results in decreased expression of CCDC141 mRNA

NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079

G

C-C motif chemokine ligand 2

decreases expression

Thalidomide analog results in decreased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

increases expression

Thalidomide results in increased expression of CCL3 mRNA

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

cyclin A2

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

decreases expression

Thalidomide analog results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin O

increases expression

Thalidomide results in increased expression of CCNO mRNA

NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914

G

CD24 molecule

affects expression

Thalidomide affects the expression of CD24A mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

CD274 molecule

decreases expression
multiple interactions

Thalidomide results in decreased expression of CD274 protein
FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of CD274 protein]

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

cell division cycle 20

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

CDC42 effector protein 5

decreases expression

Thalidomide results in decreased expression of CDC42EP5 mRNA

PMID:26006729 PMID:26217789

NCBI chr 1:70,035,921...70,038,990

G

cadherin 1

increases expression
multiple interactions

Thalidomide results in increased expression of CDH1 protein
FGD5-AS1 inhibits the reaction [Thalidomide results in increased expression of CDH1 protein]

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 10

decreases expression

Thalidomide results in decreased expression of CDH10 mRNA

NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995

G

cadherin 2

decreases expression
multiple interactions

Thalidomide results in decreased expression of CDH2 protein
FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of CDH2 protein]

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 6

increases expression

Thalidomide results in increased expression of CDH6 mRNA

NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228

G

cyclin-dependent kinase 1

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

centromere protein A

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA

NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675

G

centromere protein F

multiple interactions

[Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

cerberus 1, DAN family BMP antagonist

decreases expression

Thalidomide results in decreased expression of CER1 mRNA

NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783

G

cripto, FRL-1, cryptic family 1

decreases expression

Thalidomide results in decreased expression of CFC1 mRNA

NCBI chr 9:36,742,106...36,751,931
Ensembl chr 9:36,739,071...36,751,930

G

CASP8 and FADD-like apoptosis regulator

decreases expression

Thalidomide results in decreased expression of CFLAR protein

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

Thalidomide inhibits the reaction [TNF protein results in increased expression of CHUK protein]

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

churchill domain containing 1

decreases expression

Thalidomide results in decreased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

claudin 4

increases expression

Thalidomide results in increased expression of CLDN4 mRNA

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

claudin domain containing 1

decreases expression

Thalidomide results in decreased expression of CLDND1 mRNA

NCBI chr11:41,883,120...41,889,471
Ensembl chr11:41,883,134...41,889,354

G

C-type lectin domain containing 9A

decreases expression

Thalidomide results in decreased expression of CLEC9A mRNA

NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352

G

collagen type I alpha 1 chain

multiple interactions

Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein]

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

multiple interactions

Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of COL1A2 mRNA]

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

complexin 3

decreases expression

Thalidomide results in decreased expression of CPLX3 mRNA

NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297

G

cereblon

multiple interactions
affects binding
affects response to substance

Thalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein]
Thalidomide binds to [SALL4 protein binds to CRBN protein]; Thalidomide binds to CRBN protein
CRBN gene SNP affects the susceptibility to Thalidomide
Thalidomide binds to [CRBN protein binds to DDB1 protein]

PMID:25043012 PMID:25108355 PMID:27751757 PMID:30067223

NCBI chr 4