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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity |
ISO |
eprinomectin results in decreased activity of ABCB1A protein |
CTD |
PMID:17134887 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ano1 |
anoctamin 1 |
decreases activity |
ISO |
eprinomectin results in decreased activity of ANO1 protein |
CTD |
PMID:32201246 |
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NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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|
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity decreases expression |
ISO |
moxidectin results in decreased activity of ABCB1A protein moxidectin results in decreased expression of ABCB1 protein |
CTD |
PMID:17134887 PMID:21458446 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases export multiple interactions |
ISO |
ABCG2 protein results in increased export of moxidectin tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of moxidectin] |
CTD |
PMID:19428349 |
|
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Ano1 |
anoctamin 1 |
decreases activity |
ISO |
moxidectin results in decreased activity of ANO1 protein |
CTD |
PMID:32201246 |
|
NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
|
|
G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
moxidectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
moxidectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; moxidectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; moxidectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 PMID:27773686 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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|
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression |
ISO |
nemadectin results in decreased expression of ABCB1 mRNA; nemadectin results in decreased expression of ABCB1 protein |
CTD |
PMID:20487225 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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|
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity multiple interactions |
ISO |
selamectin results in decreased activity of ABCB1A protein [ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to selamectin |
CTD |
PMID:17134887 PMID:19161460 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
multiple interactions |
ISO |
[ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to selamectin |
CTD |
PMID:19161460 |
|
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Ano1 |
anoctamin 1 |
decreases activity |
ISO |
selamectin results in decreased activity of ANO1 protein |
CTD |
PMID:32201246 |
|
NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
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G |
Cdh1 |
cadherin 1 |
increases expression |
ISO |
selamectin results in increased expression of CDH1 |
CTD |
PMID:26078298 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Esr1 |
estrogen receptor 1 |
increases expression |
ISO |
selamectin results in increased expression of ESR1 |
CTD |
PMID:26078298 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Mxd1 |
max dimerization protein 1 |
multiple interactions |
ISO |
selamectin inhibits the reaction [MXD1 protein binds to SIN3A protein] |
CTD |
PMID:26078298 |
|
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
selamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
selamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; selamectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; selamectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 PMID:27773686 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Sin3a |
SIN3 transcription regulator family member A |
multiple interactions |
ISO |
selamectin inhibits the reaction [MXD1 protein binds to SIN3A protein] |
CTD |
PMID:26078298 |
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NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192
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