The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
[CYP1A1 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene; EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene] benzo(c)phenanthrene results in increased expression of CYP1A1 protein [[benzo(c)phenanthrene results in increased expression of CYP1A1 protein] promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; [benzo(c)phenanthrene promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog; [CYP1A1 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene; EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene] CYP1A1 protein results in increased activity of benzo(c)phenanthrene
[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]
benzo(c)phenanthrene results in increased expression of CYP1B1 protein [[benzo(c)phenanthrene results in increased expression of CYP1B1 protein] promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog
EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene]; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]
GSTP1 gene polymorphism affects the metabolism of benzo(c)phenanthrene analog GSTP1 protein affects the metabolism of [benzo(c)phenanthrene co-treated with Glutathione]
[benzo(c)phenanthrene binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; benzo(c)phenanthrene binds to and results in increased activity of NR1I2 protein