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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Antimony trioxide
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Accession:CHEBI:82289 term browser browse the term
Synonyms:xref: CAS:1309-64-4;   KEGG:C19192
 xref_mesh: MESH:C037554


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Antimony trioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO antimony trioxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO antimony trioxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO antimony trioxide results in increased expression of ITGAM protein CTD PMID:16112521 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity		 ISO [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein; Buthionine Sulfoximine promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]; Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]
MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein]		 CTD PMID:16112521 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO antimony trioxide results in increased cleavage of PARP1 protein
Glutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein]		 CTD PMID:16112521 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation		 ISO antimony trioxide affects the localization of PML protein
antimony trioxide promotes the reaction [SUMO1 protein binds to PML protein]
antimony trioxide results in increased degradation of PML protein mutant form		 CTD PMID:9834237 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO antimony trioxide results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions		 ISO antimony trioxide affects the localization of SUMO1 protein
antimony trioxide promotes the reaction [SUMO1 protein binds to PML protein]		 CTD PMID:9834237 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      atom 19878
        nonmetal atom 19800
          carbon atom 19754
            organic molecular entity 19754
              Antimony trioxide 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            Antimony trioxide 9
paths to the root