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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pioglitazone
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Accession:CHEBI:8228 term browser browse the term
Definition:A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Synonyms:exact_synonym: 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
 related_synonym: (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione;   Formula=C19H20N2O3S;   InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);   InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N;   SMILES=CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1;   pioglitazona;   pioglitazonum
 xref: CAS:111025-46-8;   Chemspider:4663;   DrugBank:DB01132;   Drug_Central:2179;   HMDB:HMDB0015264;   KEGG:C07675;   KEGG:D08378;   LINCS:LSM-1592
 xref_mesh: MESH:C060836
 xref: PMID:12879407;   PMID:14522601;   PMID:17628757;   PMID:18215232;   PMID:20797618;   PMID:27842070;   PMID:33798599;   PMID:33864097;   PMID:33983968;   PMID:33995271;   PMID:34006325;   PMID:34009030;   Patent:EP193256;   Patent:US4687777;   Reaxys:3595485;   Wikipedia:Pioglitazone


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pioglitazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABAT mRNA CTD PMID:27935865 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 affects expression
increases expression		 ISO pioglitazone affects the expression of ABCA1 protein
pioglitazone results in increased expression of ABCA1 mRNA; pioglitazone results in increased expression of ABCA1 protein		 CTD PMID:15381068 PMID:17961437 PMID:19201410 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA4 mRNA CTD PMID:27935865 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA6 mRNA CTD PMID:27935865 NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA8B mRNA CTD PMID:27935865 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO pioglitazone results in decreased activity of ABCB11 protein CTD PMID:20829430 PMID:22646477 PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Pioglitazone results in increased expression of ABCB1 mRNA CTD PMID:31233785 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCC9 mRNA CTD PMID:27935865 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Abi3bp ABI family member 3 binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA CTD PMID:27935865 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Ablim2 actin binding LIM protein family, member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABLIM2 mRNA CTD PMID:27935865 NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334 		JBrowse link
G Abra actin-binding Rho activating protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABRA mRNA CTD PMID:27935865 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO pioglitazone results in decreased expression of ACAT1 mRNA CTD PMID:15381068 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Pioglitazone results in decreased expression of ACAT2 mRNA CTD PMID:30031879 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein] CTD PMID:16979161 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression
increases secretion		 EXP Pioglitazone results in increased expression of ACE2 protein
Pioglitazone results in increased secretion of ACE2 protein		 CTD PMID:24114819 PMID:24558317 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acod1 aconitate decarboxylase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ACOD1 mRNA CTD PMID:27935865 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases activity EXP Pioglitazone results in decreased activity of ACSL4 protein CTD PMID:11319222 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTA1 mRNA CTD PMID:27935865 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP
ISO		 pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACTA2 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]		 CTD PMID:15052691 PMID:16484506 PMID:18513333 PMID:32613381 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTC1 mRNA CTD PMID:27935865 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actg2 actin gamma 2, smooth muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTG2 mRNA CTD PMID:27935865 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actn2 actinin alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTN2 mRNA CTD PMID:27935865 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Adam23 ADAM metallopeptidase domain 23 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM23 mRNA CTD PMID:27935865 NCBI chr 9:64,862,649...65,009,718
Ensembl chr 9:64,862,878...65,006,515 		JBrowse link
G Adam5 ADAM metallopeptidase domain 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM5 mRNA CTD PMID:27935865 NCBI chr16:67,223,095...67,298,733
Ensembl chr16:67,223,143...67,298,737 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA] CTD PMID:20847119 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCY5 mRNA CTD PMID:27935865 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCYAP1R1 mRNA CTD PMID:27935865 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADHFE1 mRNA CTD PMID:27935865 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
decreases expression		 ISO
EXP		 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]; [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of ADIPOQ mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; Pioglitazone promotes the reaction [Palmitates results in increased secretion of ADIPOQ protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]
pioglitazone results in increased expression of ADIPOQ mRNA; pioglitazone results in increased expression of ADIPOQ protein
Pioglitazone inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]; Pioglitazone inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]
Pioglitazone results in decreased expression of ADIPOQ protein		 CTD PMID:12927809 PMID:18303122 PMID:18513333 PMID:18815186 PMID:19048458 More... NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ADM mRNA CTD PMID:20847119 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADORA1 mRNA CTD PMID:27935865 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Agbl1 AGBL carboxypeptidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGBL1 mRNA CTD PMID:27935865 NCBI chr 1:130,043,914...130,950,739
Ensembl chr 1:130,043,970...130,951,638 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen multiple interactions EXP pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR1A mRNA CTD PMID:27935865 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR2 mRNA CTD PMID:15992368 PMID:27935865 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Aifm3 AIF family member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AIFM3 mRNA CTD PMID:27935865 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248 		JBrowse link
G Ajuba ajuba LIM protein multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AJUBA mRNA CTD PMID:20847119 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Pioglitazone inhibits the reaction [streptozocin decreases phosphorylation of Akt1 protein in the liver] RGD PMID:29379801 RGD:408346751 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alpk3 alpha-kinase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ALPK3 mRNA CTD PMID:27935865 NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMIGO2 mRNA CTD PMID:27935865 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695 		JBrowse link
G Amotl2 angiomotin like 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AMOTL2 mRNA CTD PMID:20847119 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMPD1 mRNA CTD PMID:27935865 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938 		JBrowse link
G Angpt2 angiopoietin 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein] CTD PMID:15992368 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl2 angiopoietin-like 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANGPTL2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANGPTL2 mRNA] CTD PMID:20847119 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Pioglitazone results in increased expression of ANGPTL4 mRNA CTD PMID:30031879 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ank1 ankyrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANK1 mRNA CTD PMID:27935865 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANKRD37 mRNA] CTD PMID:20847119 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Ankrd63 ankyrin repeat domain 63 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANKRD63 mRNA CTD PMID:27935865 NCBI chr 3:105,675,148...105,679,970
Ensembl chr 3:105,663,638...105,682,404 		JBrowse link
G Ano5 anoctamin 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANO5 mRNA CTD PMID:27935865 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AOC3 mRNA CTD PMID:27935865 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 decreases expression ISO Pioglitazone results in decreased expression of AP1S2 mRNA CTD PMID:30031879 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 increases expression ISO pioglitazone results in increased expression of APC2 mRNA CTD PMID:21347706 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Apob apolipoprotein B decreases expression ISO pioglitazone results in decreased expression of APOB protein CTD PMID:16324916 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc1 apolipoprotein C1 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in increased expression of APOC1 protein CTD PMID:16324916 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC2 protein
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of APOC2 mRNA		 CTD PMID:16324916 PMID:27935865 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC3 protein CTD PMID:16324916 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions		 ISO pioglitazone results in decreased expression of APP protein mutant form
pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp7 aquaporin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AQP7 mRNA CTD PMID:27935865 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Ar androgen receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AR mRNA CTD PMID:27935865 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Areg amphiregulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of AREG mRNA CTD PMID:27935865 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ARMCX2 mRNA CTD PMID:27935865 NCBI chr  X:97,980,662...97,985,523
Ensembl chr  X:97,980,660...97,985,552 		JBrowse link
G Art1 ADP-ribosyltransferase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ART1 mRNA CTD PMID:27935865 NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172 		JBrowse link
G Asb10 ankyrin repeat and SOCS box-containing 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB10 mRNA CTD PMID:27935865 NCBI chr 4:10,630,318...10,644,270
Ensembl chr 4:10,630,448...10,639,060 		JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB14 mRNA CTD PMID:27935865 NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135 		JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB5 mRNA CTD PMID:27935865 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ATF3 mRNA CTD PMID:20847119 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP1A2 mRNA CTD PMID:27935865 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP2A1 mRNA CTD PMID:27935865 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO pioglitazone results in decreased expression of ATP5F1B mRNA CTD PMID:20860658 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AVPR1A mRNA CTD PMID:27935865 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of B4GALNT2 mRNA CTD PMID:27935865 NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700 		JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA CTD PMID:27935865 NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
decreases expression
decreases activity		 ISO pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]
pioglitazone results in decreased expression of BACE1 mRNA
pioglitazone results in decreased activity of BACE1 protein
pioglitazone results in decreased expression of BACE1 mRNA; pioglitazone results in decreased expression of BACE1 protein		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA] CTD PMID:30130594 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BCHE mRNA CTD PMID:27935865 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO Pioglitazone results in decreased expression of BCL11A mRNA CTD PMID:30031879 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA] CTD PMID:30130594 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein] CTD PMID:32735850 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bend5 BEN domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BEND5 mRNA CTD PMID:27935865 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BHLHA15 mRNA CTD PMID:27935865 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Pioglitazone results in decreased expression of BIRC3 mRNA CTD PMID:30031879 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Pioglitazone results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bpifa5 BPI fold containing family A, member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of BPIFA5 mRNA CTD PMID:27935865 NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BPIFB1 mRNA CTD PMID:27935865 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G Bsg basigin multiple interactions
decreases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]
pioglitazone results in decreased expression of BSG protein		 CTD PMID:16860414 PMID:17007354 PMID:17055343 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BTN2A2 mRNA CTD PMID:27935865 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of BZW1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BZW1 mRNA] CTD PMID:20847119 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430 		JBrowse link
G C1qtnf7 C1q and TNF related 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA CTD PMID:27935865 NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410 		JBrowse link
G C2h1orf54 similar to human chromosome 1 open reading frame 54 decreases expression ISO Pioglitazone results in decreased expression of C1ORF54 mRNA CTD PMID:30031879 NCBI chr 2:183,424,989...183,434,713
Ensembl chr 2:183,424,984...183,435,089 		JBrowse link
G C4a complement C4A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C4A mRNA CTD PMID:27935865 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080 		JBrowse link
G C5ar1 complement C5a receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of C5AR1 mRNA CTD PMID:27935865 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CABCOCO1 mRNA CTD PMID:27935865 NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1C mRNA CTD PMID:27935865 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1S mRNA CTD PMID:27935865 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA2D3 mRNA CTD PMID:27935865 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Cadm2 cell adhesion molecule 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CADM2 mRNA CTD PMID:27935865 NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400 		JBrowse link
G Calhm5 calcium homeostasis modulator family member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CALHM5 mRNA CTD PMID:27935865 NCBI chr20:26,066,270...26,072,348
Ensembl chr20:26,066,242...26,072,272 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAR3 mRNA CTD PMID:27935865 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein]
[Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]		 CTD PMID:23795773 PMID:30130594 PMID:36988379 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casq1 calsequestrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CASQ1 mRNA CTD PMID:27935865 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Cat catalase multiple interactions EXP
ISO		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]		 CTD PMID:20450929 PMID:27350165 PMID:29233026 PMID:29247773 PMID:32735850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 affects expression ISO pioglitazone affects the expression of CAV1 protein CTD PMID:17961437 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAV3 mRNA CTD PMID:27935865 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ccdc159 coiled-coil domain containing 159 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC159 mRNA CTD PMID:27935865 NCBI chr 8:20,457,905...20,467,232
Ensembl chr 8:20,457,909...20,466,562 		JBrowse link
G Ccdc85a coiled-coil domain containing 85A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC85A mRNA CTD PMID:27935865 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL11 protein] CTD PMID:17015710 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCL2 mRNA; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL2 mRNA		 CTD PMID:20847119 PMID:27935865 PMID:32613381 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL3 mRNA
Pioglitazone results in decreased expression of CCL3 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases response to substance		 ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]
pioglitazone results in decreased susceptibility to CCL5 protein		 CTD PMID:17015710 PMID:18158351 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA CTD PMID:27935865 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO
EXP		 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA]
Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]		 CTD PMID:16484506 PMID:20847119 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna1 cyclin A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNA1 mRNA CTD PMID:27935865 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO pioglitazone results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO pioglitazone results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO pioglitazone results in decreased expression of CCND1 mRNA; pioglitazone results in decreased expression of CCND1 protein
Pioglitazone results in decreased expression of CCND1 mRNA
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]		 CTD PMID:17077279 PMID:26643070 PMID:30031879 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO pioglitazone results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO pioglitazone results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccno cyclin O multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNO mRNA CTD PMID:27935865 NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914 		JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions		 ISO
EXP		 Pioglitazone results in increased expression of CD36 mRNA; Pioglitazone results in increased expression of CD36 protein
pioglitazone results in increased expression of CD36 mRNA
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CD36 mRNA
Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]		 CTD PMID:15381068 PMID:16484506 PMID:17143554 PMID:19048458 PMID:20723549 More... NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd84 CD84 molecule decreases expression ISO Pioglitazone results in decreased expression of CD84 mRNA CTD PMID:30031879 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076 		JBrowse link
G Cdc20b cell division cycle 20B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDC20B mRNA CTD PMID:27935865 NCBI chr 2:44,688,349...44,738,056 JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO Pioglitazone results in decreased expression of CDC42 mRNA CTD PMID:32589349 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO pioglitazone results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkl1 cyclin dependent kinase like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDKL1 mRNA CTD PMID:27935865 NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression		 EXP
ISO		 pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]
pioglitazone results in decreased expression of CDKN1A protein
Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; Pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]		 CTD PMID:15729575 PMID:17582756 PMID:26643070 PMID:29734669 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 EXP
ISO		 pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]
pioglitazone results in increased expression of CDKN1B protein
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]		 CTD PMID:17582756 PMID:26643070 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1C mRNA CTD PMID:20847119 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO pioglitazone results in increased expression of CEBPA mRNA CTD PMID:28242381 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CEMIP mRNA CTD PMID:27935865 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO pioglitazone results in increased expression of CES1 mRNA CTD PMID:15381068 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfd complement factor D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CFD mRNA CTD PMID:27935865 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 decreases expression ISO Pioglitazone results in decreased expression of CHCHD6 mRNA CTD PMID:30031879 NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216 		JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CHI3L1 mRNA CTD PMID:27935865 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chit1 chitinase 1 decreases expression ISO Pioglitazone results in decreased expression of CHIT1 mRNA CTD PMID:30031879 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHP2 mRNA CTD PMID:27935865 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM1 mRNA CTD PMID:27935865 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM2 mRNA CTD PMID:27935865 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNA1 mRNA CTD PMID:27935865 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNE mRNA CTD PMID:27935865 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA CTD PMID:32589349 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CIDEC mRNA CTD PMID:27935865 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKM mRNA CTD PMID:27935865 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKMT2 mRNA CTD PMID:27935865 NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Clec14a C-type lectin domain containing 14A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLEC14A mRNA CTD PMID:27935865 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612 		JBrowse link
G Clec1a C-type lectin domain family 1, member A increases expression ISO Pioglitazone results in increased expression of CLEC1A mRNA CTD PMID:30031879 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247 		JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression ISO Pioglitazone results in decreased expression of CLEC4A mRNA CTD PMID:30031879 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817 		JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4D mRNA CTD PMID:27935865 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4e C-type lectin domain family 4, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4E mRNA CTD PMID:27935865 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Clstn3 calsyntenin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLSTN3 mRNA CTD PMID:27935865 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CMYA5 mRNA CTD PMID:27935865 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CNGA3 mRNA CTD PMID:27935865 NCBI chr 9:39,447,534...39,494,044
Ensembl chr 9:39,448,034...39,493,183 		JBrowse link
G Cnn1 calponin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNN1 mRNA CTD PMID:27935865 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNRIP1 mRNA CTD PMID:27935865 NCBI chr14:91,462,877...91,492,739
Ensembl chr14:91,462,647...91,492,735 		JBrowse link
G Cntd1 cyclin N-terminal domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNTD1 mRNA CTD PMID:27935865 NCBI chr10:86,221,430...86,231,812 JBrowse link
G Cog8 component of oligomeric golgi complex 8 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of COG8 mRNA CTD PMID:20847119 NCBI chr19:34,951,625...34,962,377
Ensembl chr19:34,951,627...34,962,397 		JBrowse link
G Col6a5 collagen type VI alpha 5 chain multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of COL6A5 mRNA CTD PMID:27935865 NCBI chr 8:106,483,806...106,584,114
Ensembl chr 8:106,483,799...106,584,113 		JBrowse link
G Coro6 coronin 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CORO6 mRNA CTD PMID:27935865 NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of COX6A2 mRNA CTD PMID:27935865 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA] CTD PMID:32613381 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO pioglitazone results in increased expression of CPT1B mRNA CTD PMID:20723549 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPXM1 mRNA CTD PMID:27935865 NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330 		JBrowse link
G Cpz carboxypeptidase Z multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPZ mRNA CTD PMID:27935865 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein] CTD PMID:32735850 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone increases expression ISO Pioglitazone results in increased expression of CRH mRNA CTD PMID:30031879 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRHR2 mRNA CTD PMID:27935865 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRISPLD1 mRNA CTD PMID:27935865 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926 		JBrowse link
G Crp C-reactive protein affects expression
decreases expression		 EXP
ISO		 pioglitazone affects the expression of CRP protein
Pioglitazone results in decreased expression of CRP protein		 CTD PMID:28705172 PMID:28744220 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CRYAB mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CRYAB mRNA] CTD PMID:20847119 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Crym crystallin, mu multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRYM mRNA CTD PMID:27935865 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Csn1s1 casein alpha s1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CSN1S1 mRNA CTD PMID:27935865 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CSRP3 mRNA CTD PMID:27935865 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CTLA4 mRNA CTD PMID:27935865 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CTNNB1 mRNA CTD PMID:20847119 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases response to substance
multiple interactions		 ISO pioglitazone results in decreased susceptibility to CXCL12 protein
pioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA		 CTD PMID:18158351 PMID:27935865 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL2 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA CTD PMID:27935865 PMID:28263783 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL3 mRNA CTD PMID:27935865 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCR3 mRNA CTD PMID:27935865 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CXCR4 mRNA CTD PMID:20847119 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression
affects activity		 ISO pioglitazone results in decreased expression of CYBA mRNA
pioglitazone affects the activity of CYBA protein		 CTD PMID:11172467 PMID:21962020 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases activity
decreases expression		 ISO pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased activity of CYP17A1 protein]; pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of CYP17A1 mRNA]
pioglitazone results in decreased activity of CYP17A1 protein
pioglitazone results in decreased expression of CYP17A1 mRNA		 CTD PMID:15072549 PMID:17138841 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP pioglitazone results in increased expression of CYP2B1 mRNA CTD PMID:16597547 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO pioglitazone results in increased expression of CYP2B6 protein
Pioglitazone results in increased expression of CYP2B10 mRNA		 CTD PMID:12642470 PMID:28541575 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression ISO Pioglitazone results in increased expression of CYP2C55 mRNA CTD PMID:28541575 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions
affects metabolic processing
decreases activity
increases expression		 ISO Gemfibrozil inhibits the reaction [CYP2C8 protein affects the metabolism of pioglitazone]
pioglitazone results in decreased activity of CYP2C8 protein
Pioglitazone results in increased expression of CYP2C8 mRNA		 CTD PMID:12642470 PMID:15900286 PMID:31233785
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2G1 mRNA CTD PMID:27935865 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
affects metabolic processing
decreases activity		 EXP
ISO		 pioglitazone inhibits the reaction [Endotoxins results in decreased expression of CYP3A2 protein]
[Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; Pioglitazone results in increased expression of and results in increased activity of CYP3A4 protein
Pioglitazone results in increased expression of CYP3A4 mRNA; Pioglitazone results in increased expression of CYP3A4 protein
CYP3A4 protein affects the metabolism of Pioglitazone
Pioglitazone results in decreased activity of CYP3A4 protein		 CTD PMID:12642470 PMID:15364003 PMID:15860655 PMID:15900286 PMID:16837568 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Pioglitazone results in increased expression of CYP3A23-3A1 mRNA CTD PMID:16597547 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [U 0126 results in increased expression of CYP7A1 mRNA]; U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA] CTD PMID:22593575 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DCAF12L1 mRNA CTD PMID:27935865 NCBI chr  X:123,695,286...123,698,905
Ensembl chr  X:123,695,286...123,698,905 		JBrowse link
G Dcx doublecortin multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein] CTD PMID:32735850 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DDAH1 mRNA CTD PMID:27935865 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression		 ISO [Metformin co-treated with Pioglitazone] results in increased expression of DDIT4 mRNA
Pioglitazone results in increased expression of DDIT4 mRNA		 CTD PMID:32589349 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like multiple interactions
increases expression		 ISO [Metformin co-treated with Pioglitazone] results in increased expression of DDIT4L mRNA
Pioglitazone results in increased expression of DDIT4L mRNA		 CTD PMID:32589349 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375 		JBrowse link
G Depp1 DEPP autophagy regulator 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DEPP1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DEPP1 mRNA] CTD PMID:20847119 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of DEPTOR mRNA CTD PMID:32589349 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Derl3 derlin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DERL3 mRNA CTD PMID:27935865 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Des desmin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA CTD PMID:27935865 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Deup1 deuterosome assembly protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DEUP1 mRNA CTD PMID:27935865 NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO pioglitazone results in increased expression of DGAT1 mRNA CTD PMID:20723549 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression ISO pioglitazone results in increased expression of DGAT2 mRNA CTD PMID:20723549 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhrs7c dehydrogenase/reductase 7C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DHRS7C mRNA CTD PMID:27935865 NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity
multiple interactions
increases expression		 ISO pioglitazone results in increased activity of DIO2 protein
PPARG protein promotes the reaction [pioglitazone results in increased activity of DIO2 protein]
pioglitazone results in increased expression of DIO2 mRNA		 CTD PMID:19036883 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO pioglitazone results in decreased activity of DIO3 protein CTD PMID:19036883 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DLG1 mRNA] CTD PMID:20847119 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DMBT1 mRNA CTD PMID:27935865 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dnaaf2 dynein, axonemal, assembly factor 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of DNAAF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of DNAAF2 mRNA] CTD PMID:20847119 NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNAH8 mRNA CTD PMID:27935865 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772 		JBrowse link
G Dner delta/notch-like EGF repeat containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNER mRNA CTD PMID:27935865 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dpt dermatopontin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA CTD PMID:27935865 NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Dpy19l2 dpy-19 like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPY19L2 mRNA CTD PMID:27935865 NCBI chr 8:23,062,592...23,181,817
Ensembl chr 8:23,063,115...23,181,798 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DRD1 mRNA CTD PMID:27935865 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Dusp10 dual specificity phosphatase 10 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DUSP10 mRNA CTD PMID:20847119 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp26 dual specificity phosphatase 26 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DUSP26 mRNA CTD PMID:27935865 NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051 		JBrowse link
G Eddm3b epididymal protein 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of EDDM3B mRNA CTD PMID:27935865 NCBI chr15:24,343,992...24,346,759
Ensembl chr15:24,345,573...24,346,025 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EEF1A2 mRNA CTD PMID:27935865 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGF mRNA CTD PMID:27935865 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGFLAM mRNA CTD PMID:27935865 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA CTD PMID:32589349 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
increases expression		 ISO pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]
pioglitazone results in decreased phosphorylation of EIF4EBP1 protein
Pioglitazone results in increased expression of EIF4EBP1 mRNA		 CTD PMID:26643070 PMID:32589349 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Pioglitazone results in increased expression of EIF4EBP2 mRNA CTD PMID:32589349 NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO pioglitazone results in increased expression of EIF5A mRNA CTD PMID:21347706 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO Pioglitazone results in increased expression of ELOVL4 mRNA CTD PMID:30031879 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Eno3 enolase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA CTD PMID:27935865 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Epgn epithelial mitogen multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of EPGN mRNA CTD PMID:27935865 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA3 mRNA CTD PMID:27935865 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha5 EPH receptor A5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA5 mRNA CTD PMID:27935865 NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317 		JBrowse link
G Epyc epiphycan multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPYC mRNA CTD PMID:27935865 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135 		JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ERBIN mRNA] CTD PMID:20847119 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ereg epiregulin increases expression ISO Pioglitazone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G F10 coagulation factor X multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of F10 mRNA CTD PMID:27935865 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FABP3 mRNA CTD PMID:27935865 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO [pioglitazone co-treated with Tretinoin] results in increased expression of FABP4 mRNA
Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]
pioglitazone results in increased expression of FABP4 mRNA
Pioglitazone results in increased expression of FABP4 mRNA		 CTD PMID:9543393 PMID:12927809 PMID:15273253 PMID:16573735 PMID:17290005 More... NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO Pioglitazone results in increased expression of FAM13A mRNA CTD PMID:30031879 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Fam171b family with sequence similarity 171, member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM171B mRNA CTD PMID:27935865 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127 		JBrowse link
G Fam184b family with sequence similarity 184, member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM184B mRNA CTD PMID:27935865 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388 		JBrowse link
G Fam210a family with sequence similarity 210, member A multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of FAM210A mRNA CTD PMID:20847119 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171 		JBrowse link
G Fam240b family with sequence similarity 240 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of FAM240B mRNA CTD PMID:27935865 NCBI chr17:647,269...663,209
Ensembl chr17:657,303...663,206 		JBrowse link
G Fam47e family with sequence similarity 47, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM47E mRNA CTD PMID:27935865 NCBI chr14:15,485,537...15,521,599
Ensembl chr14:15,485,127...15,521,775 		JBrowse link
G Fat4 FAT atypical cadherin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAT4 mRNA CTD PMID:27935865 NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Pioglitazone results in increased expression of FBLN1 mRNA CTD PMID:30031879 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fbln7 fibulin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBLN7 mRNA CTD PMID:27935865 NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983 		JBrowse link
G Fbxl16 F-box and leucine-rich repeat protein 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXL16 mRNA CTD PMID:27935865 NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986 		JBrowse link
G Fbxo40 F-box protein 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO40 mRNA CTD PMID:27935865 NCBI chr11:63,794,452...63,812,697
Ensembl chr11:63,794,624...63,812,697 		JBrowse link
G Fbxo43 F-box protein 43 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO43 mRNA CTD PMID:27935865 NCBI chr 7:67,333,161...67,346,751
Ensembl chr 7:67,333,162...67,346,751 		JBrowse link
G Fcmr Fc mu receptor increases expression ISO Pioglitazone results in increased expression of FCMR mRNA CTD PMID:30031879 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO pioglitazone results in increased expression of FGF21 mRNA CTD PMID:21720023 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGF7 mRNA CTD PMID:27935865 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgl1 fibrinogen-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGL1 mRNA CTD PMID:27935865 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression ISO Pioglitazone results in increased expression of FHL1 mRNA CTD PMID:30031879 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Filip1 filamin A interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FILIP1 mRNA CTD PMID:27935865 NCBI chr 8:80,761,283...80,956,556
Ensembl chr 8:80,764,604...80,922,549 		JBrowse link
G Fjx1 four-jointed box kinase 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of FJX1 mRNA CTD PMID:20847119 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression ISO Pioglitazone results in increased expression of FKBP1A mRNA CTD PMID:32589349 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 increases expression ISO Pioglitazone results in increased expression of FKBP8 mRNA CTD PMID:32589349 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Flnc filamin C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FLNC mRNA CTD PMID:27935865 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FNDC5 mRNA CTD PMID:27935865 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP pioglitazone results in increased expression of FOS mRNA CTD PMID:11687581 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSB mRNA CTD PMID:27935865 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSL1 mRNA CTD PMID:27935865 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxn4 forkhead box N4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FOXN4 mRNA CTD PMID:27935865 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921 		JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression ISO Pioglitazone results in decreased expression of FPR1 mRNA CTD PMID:30031879 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559 		JBrowse link
G Frzb frizzled-related protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FRZB mRNA CTD PMID:27935865 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 decreases expression ISO Pioglitazone results in decreased expression of FSCN1 mRNA CTD PMID:30031879 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fsd2 fibronectin type III and SPRY domain containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FSD2 mRNA CTD PMID:27935865 NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472 		JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FXYD1 mRNA CTD PMID:27935865 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA3 mRNA CTD PMID:27935865 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA4 mRNA CTD PMID:27935865 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GALNT16 mRNA CTD PMID:27935865 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705 		JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of GALNT17 mRNA CTD PMID:27935865 NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290 		JBrowse link
G Galnt9 polypeptide N-acetylgalactosaminyltransferase 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GALNT9 mRNA CTD PMID:27935865 NCBI chr12:46,050,395...46,128,626
Ensembl chr12:46,050,413...46,128,578 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA CTD PMID:27935865 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of GEM mRNA CTD PMID:20847119 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 multiple interactions ISO [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of GEMIN4 mRNA CTD PMID:20847119 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GFRA1 mRNA CTD PMID:27935865 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gh1 growth hormone 1 increases expression ISO Pioglitazone results in increased expression of GH1 mRNA CTD PMID:30031879 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gimap4 GTPase, IMAP family member 4 decreases expression ISO Pioglitazone results in decreased expression of GIMAP4 mRNA CTD PMID:30031879 NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306 		JBrowse link
G Gldn gliomedin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GLDN mRNA CTD PMID:27935865 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196 		JBrowse link
G Gmnc geminin coiled-coil domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GMNC mRNA CTD PMID:27935865 NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328 		JBrowse link
G Gnat3 G protein subunit alpha transducin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GNAT3 mRNA CTD PMID:27935865 NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GOT1 protein] CTD PMID:15318101 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GOT1L1 mRNA CTD PMID:27935865 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Gp2 glycoprotein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GP2 mRNA CTD PMID:27935865 NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPIHBP1 mRNA CTD PMID:27935865 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702 		JBrowse link
G Gpm6a glycoprotein m6a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPM6A mRNA CTD PMID:27935865 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO Pioglitazone results in decreased expression of GPR183 mRNA CTD PMID:30031879 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Gpr84 G protein-coupled receptor 84 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GPR84 mRNA CTD PMID:27935865 NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178 		JBrowse link
G Gprasp2 G protein-coupled receptor associated sorting protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPRASP2 mRNA CTD PMID:27935865 NCBI chr  X:98,817,668...98,823,814
Ensembl chr  X:98,817,593...98,824,402 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein] CTD PMID:15318101 PMID:27350165 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Pioglitazone results in increased expression of GPX3 mRNA CTD PMID:30031879 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GRM4 mRNA CTD PMID:27935865 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression ISO Pioglitazone results in increased expression of GSK3B mRNA CTD PMID:32589349 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions EXP [pioglitazone co-treated with alitretinoin] results in increased expression of GSTA2 protein CTD PMID:15150131 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP pioglitazone inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] CTD PMID:15526359 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GSTT1 mRNA CTD PMID:27935865 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GUCY1A1 mRNA CTD PMID:27935865 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Hbb hemoglobin subunit beta multiple interactions EXP Pioglitazone inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] CTD PMID:25679220 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hecw1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HECW1 mRNA CTD PMID:27935865 NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720 		JBrowse link
G Hhatl hedgehog acyltransferase-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHATL mRNA CTD PMID:27935865 NCBI chr 8:121,447,001...121,454,070
Ensembl chr 8:121,447,002...121,454,001 		JBrowse link
G Hhip Hedgehog-interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHIP mRNA CTD PMID:27935865 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 ISO Pioglitazone results in decreased expression of HIF1A mRNA
[Metformin co-treated with Pioglitazone] results in decreased expression of HIF1A mRNA		 CTD PMID:32589349 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha decreases expression EXP pioglitazone results in decreased expression of HIF3A mRNA CTD PMID:22456468 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HILPDA mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HILPDA mRNA] CTD PMID:20847119 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hjv hemojuvelin BMP co-receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of HJV mRNA CTD PMID:27935865 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression		 ISO pioglitazone results in increased expression of HMGCR mRNA
pioglitazone results in decreased expression of HMGCR mRNA		 CTD PMID:12044893 PMID:20503262 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO pioglitazone results in increased expression of HMGCS1 mRNA CTD PMID:12044893 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 EXP
ISO		 pioglitazone results in increased expression of HMOX1 mRNA
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA
Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]		 CTD PMID:16597547 PMID:28263783 PMID:30965670 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HNRNPDL mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HNRNPDL mRNA] CTD PMID:20847119 NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO [pioglitazone co-treated with NAD] binds to HPGD protein CTD PMID:25526675 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hpse2 heparanase 2 (inactive) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HPSE2 mRNA CTD PMID:27935865 NCBI chr 1:241,582,904...242,284,348
Ensembl chr 1:241,583,187...242,246,118 		JBrowse link
G Hrc histidine rich calcium binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HRC mRNA CTD PMID:27935865 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression
decreases activity		 ISO pioglitazone results in decreased expression of HSD3B2 mRNA
pioglitazone results in decreased activity of HSD3B2 protein		 CTD PMID:15072549 PMID:17138841 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Hspa12b heat shock protein family A (Hsp70) member 12B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPA12B mRNA CTD PMID:27935865 NCBI chr 3:118,346,372...118,364,374
Ensembl chr 3:118,346,354...118,364,737 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA1L mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HSPA1L mRNA] CTD PMID:20847119 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPB7 mRNA CTD PMID:27935865 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of HTR2B mRNA CTD PMID:27935865 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of ICAM1 protein] CTD PMID:17015710 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [Pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ID2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ID2 mRNA] CTD PMID:20847119 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Ifng interferon gamma multiple interactions ISO pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form] CTD PMID:14586007 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
multiple interactions		 ISO Pioglitazone results in decreased expression of IGF1 mRNA
[Metformin co-treated with Pioglitazone] results in decreased expression of IGF1 mRNA		 CTD PMID:32589349 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igsf10 immunoglobulin superfamily, member 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IGSF10 mRNA CTD PMID:27935865 NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases expression ISO Pioglitazone results in decreased expression of IKBKB mRNA CTD PMID:32589349 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 EXP
ISO		 Pioglitazone inhibits the reaction [propionic acid results in decreased expression of IL10 protein]
Pioglitazone results in increased expression of IL10 protein		 CTD PMID:27918843 PMID:31348919 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il13 interleukin 13 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL13 protein] CTD PMID:17015710 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP pioglitazone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Pioglitazone results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression
increases expression		 ISO
EXP		 Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]
pioglitazone affects the expression of IL1B mRNA
[pioglitazone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA
Pioglitazone results in increased expression of IL1B mRNA
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of IL1B protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]		 CTD PMID:14586007 PMID:25679220 PMID:28138970 PMID:30031879 PMID:30130594 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL23A mRNA CTD PMID:27935865 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il24 interleukin 24 multiple interactions
increases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL24 mRNA
Pioglitazone results in increased expression of IL24 mRNA		 CTD PMID:27935865 PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 protein] CTD PMID:17015710 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein] CTD PMID:17015710 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions
affects expression
increases expression		 ISO
EXP		 [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of IL6 mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in decreased expression of IL6 protein; Pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Pioglitazone promotes the reaction [Plant Extracts results in increased expression of IL6 protein]
pioglitazone affects the expression of IL6 protein
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [propionic acid results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
Pioglitazone results in increased expression of IL6 protein		 CTD PMID:18513333 PMID:27918843 PMID:28263783 PMID:28744220 PMID:29233026 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ilk integrin-linked kinase decreases expression ISO Pioglitazone results in decreased expression of ILK mRNA CTD PMID:32589349 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Inmt indolethylamine N-methyltransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of INMT mRNA CTD PMID:27935865 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Ins1 insulin 1 multiple interactions
affects expression
decreases secretion		 EXP
ISO		 Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]
Pioglitazone promotes the reaction [INS1 protein results in increased uptake of Glucose]
Pioglitazone affects the expression of INS1 protein
Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]
Pioglitazone results in decreased secretion of INS1 protein		 CTD PMID:14532171 PMID:19208898 PMID:27350165 PMID:28242381 PMID:29233026 More... NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]
[Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]		 CTD PMID:15273253 PMID:17290005 PMID:31016361 PMID:32473317 PMID:32613381 More... NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insyn2b inhibitory synaptic factor family member 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of INSYN2B mRNA CTD PMID:27935865 NCBI chr10:18,916,721...19,023,859
Ensembl chr10:19,003,131...19,022,139 		JBrowse link
G Iqch IQ motif containing H multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IQCH mRNA CTD PMID:27935865 NCBI chr 8:63,889,816...64,083,248
Ensembl chr 8:63,892,370...64,083,223 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of IRAG1 mRNA CTD PMID:27935865 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Isl1 ISL LIM homeobox 1 increases expression ISO Pioglitazone results in increased expression of ISL1 mRNA CTD PMID:30031879 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Ism2 isthmin 2 increases expression ISO Pioglitazone results in increased expression of ISM2 mRNA CTD PMID:30031879 NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514 		JBrowse link
G Itga8 integrin subunit alpha 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGA8 mRNA CTD PMID:27935865 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ITGAV mRNA] CTD PMID:20847119 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGB1BP2 mRNA CTD PMID:27935865 NCBI chr  X:66,572,537...66,577,174
Ensembl chr  X:66,572,537...66,577,174 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITIH2 mRNA CTD PMID:27935865 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Itln1 intelectin 1 increases expression ISO pioglitazone results in increased expression of ITLN1 protein CTD PMID:23555749 NCBI chr13:83,932,234...83,958,243
Ensembl chr13:83,948,124...83,958,227 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JCHAIN mRNA CTD PMID:27935865 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jph2 junctophilin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JPH2 mRNA CTD PMID:27935865 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904 		JBrowse link
G Jsrp1 junctional sarcoplasmic reticulum protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of JSRP1 mRNA CTD PMID:27935865 NCBI chr 7:8,889,486...8,906,055
Ensembl chr 7:8,901,609...8,906,055 		JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KANK4 mRNA CTD PMID:27935865 NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNB1 mRNA CTD PMID:27935865 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNC4 mRNA CTD PMID:27935865 NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCND3 mRNA CTD PMID:27935865 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ11 mRNA CTD PMID:27935865 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ13 mRNA CTD PMID:27935865 NCBI chr 9:88,063,003...88,071,112
Ensembl chr 9:88,063,003...88,071,112 		JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of KLF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KLF2 mRNA] CTD PMID:20847119 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf5 KLF transcription factor 5 multiple interactions EXP Pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; Pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Klhl13 kelch-like family member 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL13 mRNA CTD PMID:27935865 NCBI chr  X:113,942,309...114,107,299
Ensembl chr  X:113,942,309...114,107,321 		JBrowse link
G Klhl31 kelch-like family member 31 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL31 mRNA CTD PMID:27935865 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Klhl40 kelch-like family member 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL40 mRNA CTD PMID:27935865 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Klhl41 kelch-like family member 41 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL41 mRNA CTD PMID:27935865 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Klk6 kallikrein related-peptidase 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KLK6 mRNA CTD PMID:27935865 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Krt16 keratin 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT16 mRNA CTD PMID:27935865 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt20 keratin 20 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT20 mRNA CTD PMID:27935865 NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107 		JBrowse link
G Krt84 keratin 84 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT84 mRNA CTD PMID:27935865 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874 		JBrowse link
G Krt90 keratin 90 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of KRT90 mRNA CTD PMID:27935865 NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759 		JBrowse link
G Ky kyphoscoliosis peptidase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KY mRNA CTD PMID:27935865 NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024 		JBrowse link
G Lama2 laminin subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LAMA2 mRNA CTD PMID:27935865 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LARP6 mRNA CTD PMID:27935865 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535 		JBrowse link
G Lce1f late cornified envelope 1F multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LCE1F mRNA CTD PMID:27935865 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression
multiple interactions		 ISO pioglitazone results in increased expression of LDLR protein
[pioglitazone co-treated with U 0126] affects the localization of LDLR protein		 CTD PMID:22593575 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin increases expression EXP pioglitazone results in increased expression of LEP protein CTD PMID:15655531 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor increases response to substance
multiple interactions		 EXP
ISO		 LEPR gene mutant form results in increased susceptibility to Pioglitazone
Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein]; Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein]		 CTD PMID:29743445 PMID:35472412 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LGI1 mRNA CTD PMID:27935865 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616 		JBrowse link
G Lhfpl4 LHFPL tetraspan subfamily member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LHFPL4 mRNA CTD PMID:27935865 NCBI chr 4:146,317,110...146,340,073
Ensembl chr 4:146,313,541...146,340,463 		JBrowse link
G Lipc lipase C, hepatic type increases expression ISO pioglitazone results in increased expression of LIPC mRNA CTD PMID:20503262 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipf lipase F, gastric type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LIPF mRNA CTD PMID:27935865 NCBI chr 1:231,493,498...231,511,845
Ensembl chr 1:231,493,498...231,511,845 		JBrowse link
G Lipn lipase, family member N multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LIPN mRNA CTD PMID:27935865 NCBI chr 1:231,584,950...231,603,456
Ensembl chr 1:231,584,956...231,603,468 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of LITAF mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of LITAF mRNA] CTD PMID:20847119 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Lman1l lectin, mannose-binding, 1 like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMAN1L mRNA CTD PMID:27935865 NCBI chr 8:58,010,839...58,029,599
Ensembl chr 8:58,010,839...58,023,681 		JBrowse link
G Lmod3 leiomodin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMOD3 mRNA CTD PMID:27935865 NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244 		JBrowse link
G LOC120098377 U1 spliceosomal RNA decreases expression ISO Pioglitazone results in decreased expression of RNVU1-7 mRNA CTD PMID:30031879 NCBI chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477 		JBrowse link
G Lrrc39 leucine rich repeat containing 39 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC39 mRNA CTD PMID:27935865 NCBI chr 2:204,516,122...204,535,463
Ensembl chr 2:204,516,123...204,535,463 		JBrowse link
G Lrrc3b leucine rich repeat containing 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC3B mRNA CTD PMID:27935865 NCBI chr15:9,973,580...10,050,891
Ensembl chr15:9,969,983...10,051,066 		JBrowse link
G Lrrn1 leucine rich repeat neuronal 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN1 mRNA CTD PMID:27935865 NCBI chr 4:140,476,752...140,520,210
Ensembl chr 4:140,476,324...140,518,620 		JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN3 mRNA CTD PMID:27935865 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330 		JBrowse link
G Magix MAGI family member, X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MAGIX mRNA CTD PMID:27935865 NCBI chr  X:14,824,114...14,832,466
Ensembl chr  X:14,824,188...14,831,045 		JBrowse link
G Maob monoamine oxidase B multiple interactions ISO pioglitazone binds to and results in decreased activity of MAOB protein CTD PMID:22282722 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 EXP
ISO		 pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; pioglitazone results in increased phosphorylation of and results in increased activity of MAPK1 protein
[PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:11687581 PMID:17063547 PMID:26643070 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP
ISO		 pioglitazone results in increased phosphorylation of and results in increased activity of MAPK3 protein
pioglitazone results in decreased phosphorylation of MAPK3 protein
[PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:11687581 PMID:26643070 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mb myoglobin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MB mRNA CTD PMID:27935865 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mb21d2 Mab-21 domain containing 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of MB21D2 mRNA CTD PMID:20847119 NCBI chr11:71,825,748...71,924,770
Ensembl chr11:71,825,748...71,924,769 		JBrowse link
G Mcemp1 mast cell-expressed membrane protein 1 increases expression ISO Pioglitazone results in increased expression of MCEMP1 mRNA CTD PMID:30031879 NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986 		JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MCIDAS mRNA CTD PMID:27935865 NCBI chr 2:44,636,820...44,644,551
Ensembl chr 2:44,636,856...44,642,601 		JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MEF2C mRNA CTD PMID:27935865 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Pioglitazone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mettl21cl1 methyltransferase like 21C-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of METTL21E mRNA CTD PMID:27935865 NCBI chr 9:46,382,141...46,397,299
Ensembl chr 9:46,383,687...46,397,266 		JBrowse link
G Mfap4 microfibril associated protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MFAP4 mRNA CTD PMID:27935865 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155 		JBrowse link
G Mgam maltase-glucoamylase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of MGAM mRNA CTD PMID:27935865 NCBI chr 4:69,441,626...69,602,068
Ensembl chr 4:69,446,150...69,692,715 		JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR133B mRNA CTD PMID:28263783 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217 		JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR206 mRNA CTD PMID:28263783 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mlip muscular LMNA-interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MLIP mRNA CTD PMID:27935865 NCBI chr 8:77,935,087...78,204,725
Ensembl chr 8:77,935,079...78,204,254 		JBrowse link
G Mme membrane metallo-endopeptidase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MME mRNA CTD PMID:27935865 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP12 mRNA CTD PMID:27935865 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP pioglitazone affects the reaction [Carbon Tetrachloride results in increased cleavage of MMP13 protein] CTD PMID:16484506 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
decreases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP7 mRNA
Pioglitazone results in decreased expression of MMP7 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp8 matrix metallopeptidase 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP8 mRNA CTD PMID:27935865 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases secretion
decreases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]
pioglitazone results in decreased secretion of MMP9 protein
Pioglitazone results in decreased expression of MMP9 mRNA		 CTD PMID:16860414 PMID:17055343 PMID:30031879 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ms4a7 membrane spanning 4-domains A7 increases expression ISO Pioglitazone results in increased expression of MS4A7 mRNA CTD PMID:30031879 NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260 		JBrowse link
G Mstn myostatin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MSTN mRNA CTD PMID:27935865 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 increases expression ISO Pioglitazone results in increased expression of MTARC1 mRNA CTD PMID:30031879 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of MTOR mRNA CTD PMID:32589349 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO Pioglitazone results in decreased expression of MUC1 mRNA CTD PMID:30031879 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MUC5B mRNA CTD PMID:27935865 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Mucl3 mucin like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MUCL3 mRNA CTD PMID:27935865 NCBI chr20:3,100,652...3,108,569
Ensembl chr20:3,100,679...3,108,569 		JBrowse link
G Mxd1 max dimerization protein 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of MXD1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of MXD1 mRNA] CTD PMID:20847119 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751 		JBrowse link
G Mybpc1 myosin binding protein C1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYBPC1 mRNA CTD PMID:27935865 NCBI chr 7:22,930,350...23,015,981
Ensembl chr 7:22,930,350...23,015,957 		JBrowse link
G Myf6 myogenic factor 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYF6 mRNA CTD PMID:27935865 NCBI chr 7:42,813,008...42,814,852
Ensembl chr 7:42,812,792...42,814,852 		JBrowse link
G Myh1 myosin heavy chain 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH1 mRNA CTD PMID:27935865 NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295 		JBrowse link
G Myh11 myosin heavy chain 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH11 mRNA CTD PMID:27935865 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Myh13 myosin heavy chain 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH13 mRNA CTD PMID:27935865 NCBI chr10:52,012,779...52,068,960
Ensembl chr10:52,009,425...52,068,951 		JBrowse link
G Myh2 myosin heavy chain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH2 mRNA CTD PMID:27935865 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236 		JBrowse link
G Myh4 myosin heavy chain 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of MYH4 mRNA CTD PMID:27935865 NCBI chr10:51,923,149...51,946,297
Ensembl chr10:51,885,913...51,946,295 		JBrowse link
G Myl1 myosin, light chain 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL1 mRNA CTD PMID:27935865 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261 		JBrowse link
G Myl11 myosin light chain 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of MYLPF mRNA CTD PMID:27935865 NCBI chr 1:181,829,703...181,832,546
Ensembl chr 1:181,829,743...181,832,545 		JBrowse link
G Myl9 myosin light chain 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL9 mRNA CTD PMID:27935865 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYLK mRNA CTD PMID:27935865 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Myo18b myosin XVIIIb multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYO18B mRNA CTD PMID:27935865 NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695 		JBrowse link
G Myo1c myosin 1C increases expression ISO Pioglitazone results in increased expression of MYO1C mRNA CTD PMID:32589349 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myom1 myomesin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM1 mRNA CTD PMID:27935865 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344 		JBrowse link
G Myom2 myomesin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM2 mRNA CTD PMID:27935865 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Myom3 myomesin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA CTD PMID:27935865 NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274 		JBrowse link
G Myot myotilin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOT mRNA CTD PMID:27935865 NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841 		JBrowse link
G Myoz1 myozenin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ1 mRNA CTD PMID:27935865 NCBI chr15:3,644,333...3,651,584
Ensembl chr15:3,644,368...3,652,884 		JBrowse link
G Myoz3 myozenin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ3 mRNA CTD PMID:27935865 NCBI chr18:54,026,133...54,046,151
Ensembl chr18:54,026,152...54,102,126 		JBrowse link
G Mypn myopalladin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYPN mRNA CTD PMID:27935865 NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MZB1 mRNA CTD PMID:27935865 NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NAALAD2 mRNA CTD PMID:27935865 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of NDRG1 mRNA CTD PMID:20847119 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Neb nebulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEB mRNA CTD PMID:27935865 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574 		JBrowse link
G Negr1 neuronal growth regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEGR1 mRNA CTD PMID:27935865 NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730 		JBrowse link
G Nexn nexilin (F actin binding protein) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEXN mRNA CTD PMID:27935865 NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA]; Pioglitazone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA] CTD PMID:30965670 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO pioglitazone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIB protein] CTD PMID:17055343 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Nkain3 Sodium/potassium transporting ATPase interacting 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKAIN3 mRNA CTD PMID:27935865 NCBI chr 5:33,613,720...34,310,090
Ensembl chr 5:33,623,713...34,309,381 		JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKX3-1 mRNA CTD PMID:27935865 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nmrk2 nicotinamide riboside kinase 2 decreases expression ISO Pioglitazone results in decreased expression of NMRK2 mRNA CTD PMID:30031879 NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
affects expression		 ISO
EXP		 pioglitazone inhibits the reaction [Homocysteine results in increased methylation of NOS2 promoter]
Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]; Pioglitazone inhibits the reaction [Endotoxins results in increased expression of NOS2 protein]
pioglitazone results in decreased expression of NOS2 mRNA
pioglitazone affects the expression of NOS2		 CTD PMID:15364003 PMID:15817521 PMID:17492134 PMID:21962020 PMID:30343038 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein] CTD PMID:30343038 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox1 NADPH oxidase 1 affects activity ISO pioglitazone affects the activity of NOX1 protein CTD PMID:21962020 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA] CTD PMID:16979161 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin increases expression EXP Pioglitazone results in increased expression of NPHS1 mRNA; Pioglitazone results in increased expression of NPHS1 protein CTD PMID:16687628 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078 		JBrowse link
G Nppb natriuretic peptide B decreases expression ISO Pioglitazone results in decreased expression of NPPB mRNA CTD PMID:30031879 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Npy neuropeptide Y multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of NPY mRNA CTD PMID:27935865 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NPY1R mRNA CTD PMID:27935865 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NQO1 mRNA] CTD PMID:30965670 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases expression ISO pioglitazone results in increased expression of NR1H2 mRNA CTD PMID:19201410 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
affects response to substance
increases expression		 ISO 22-hydroxycholesterol promotes the reaction [pioglitazone results in increased expression of NR1H3 mRNA]; NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA]
NR1H3 protein affects the susceptibility to pioglitazone		 CTD PMID:15381068 PMID:19201410 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects localization ISO Pioglitazone affects the localization of NR1I2 protein CTD PMID:31233785 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO pioglitazone results in increased expression of NR4A1 mRNA CTD PMID:17785466 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO pioglitazone results in increased expression of NR4A3 mRNA CTD PMID:17785466 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nrap nebulin-related anchoring protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NRAP mRNA CTD PMID:27935865 NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693 		JBrowse link
G Nsg2 neuronal vesicle trafficking associated 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NSG2 mRNA CTD PMID:27935865 NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441 		JBrowse link
G Nucb2 nucleobindin 2 increases stability ISO pioglitazone results in increased stability of NUCB2 mRNA CTD PMID:20427483 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OBSCN mRNA CTD PMID:27935865 NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions ISO Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein] CTD PMID:35472412 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Olfml1 olfactomedin-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OLFML1 mRNA CTD PMID:27935865 NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537 		JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPCML mRNA CTD PMID:27935865 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620 		JBrowse link
G Optc opticin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPTC mRNA CTD PMID:27935865 NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237 		JBrowse link
G Pax1 paired box 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PAX1 mRNA CTD PMID:27935865 NCBI chr 3:134,792,330...134,801,637
Ensembl chr 3:134,789,182...134,801,636 		JBrowse link
G Pcdh18 protocadherin 18 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCDH18 mRNA CTD PMID:27935865 NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCK1 mRNA CTD PMID:27935865 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCLO mRNA CTD PMID:27935865 NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885 		JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 increases expression ISO Pioglitazone results in increased expression of PCOLCE2 mRNA CTD PMID:30031879 NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA]
pioglitazone results in increased expression of PCSK9 mRNA; pioglitazone results in increased expression of PCSK9 protein
[pioglitazone co-treated with U 0126] results in increased secretion of PCSK9 protein		 CTD PMID:22593575 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pde6c phosphodiesterase 6C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDE6C mRNA CTD PMID:27935865 NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]; [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]] CTD PMID:26643070 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDGFRA mRNA CTD PMID:27935865 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Pioglitazone results in increased expression of PDK4 mRNA CTD PMID:30031879 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Pioglitazone results in increased expression of PEG10 mRNA CTD PMID:30031879 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PERM1 mRNA CTD PMID:27935865 NCBI chr 5:166,800,030...166,805,323
Ensembl chr 5:166,800,030...166,805,323 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGAM2 mRNA CTD PMID:27935865 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940 		JBrowse link
G Pgm5 phosphoglucomutase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGM5 mRNA CTD PMID:27935865 NCBI chr 1:222,325,638...222,513,434
Ensembl chr 1:222,325,643...222,513,437 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHACTR1 mRNA CTD PMID:27935865 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Pheta2 PH domain containing endocytic trafficking adaptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHETA2 mRNA CTD PMID:27935865 NCBI chr 7:113,855,437...113,861,910
Ensembl chr 7:113,857,249...113,861,871 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHEX mRNA CTD PMID:27935865 NCBI chr  X:37,607,553...37,856,183
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Phgr1 proline, histidine and glycine rich 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PHGR1 mRNA CTD PMID:27935865 NCBI chr 3:105,742,822...105,760,835
Ensembl chr 3:105,757,581...105,760,832 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Pioglitazone results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Piezo2 piezo-type mechanosensitive ion channel component 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PIEZO2 mRNA CTD PMID:27935865 NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3C3 mRNA CTD PMID:32589349 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions
decreases expression		 ISO [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CA mRNA
Pioglitazone results in decreased expression of PIK3CA mRNA		 CTD PMID:32589349 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CB mRNA CTD PMID:32589349 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CG mRNA CTD PMID:32589349 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pknox2 PBX/knotted 1 homeobox 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PKNOX2 mRNA CTD PMID:27935865 NCBI chr 8:36,600,633...36,863,131
Ensembl chr 8:36,600,636...36,790,940 		JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLAAT1 mRNA CTD PMID:27935865 NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020 		JBrowse link
G Pld1 phospholipase D1 decreases expression
multiple interactions		 ISO Pioglitazone results in decreased expression of PLD1 mRNA
[Metformin co-treated with Pioglitazone] results in decreased expression of PLD1 mRNA		 CTD PMID:32589349 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Plek pleckstrin decreases expression ISO Pioglitazone results in decreased expression of PLEK mRNA CTD PMID:30031879 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:27935865 PMID:32473317 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plin2 perilipin 2 increases expression ISO Pioglitazone results in increased expression of PLIN2 mRNA CTD PMID:15381068 PMID:30031879 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plin4 perilipin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLIN4 mRNA CTD PMID:27935865 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056 		JBrowse link
G Pln phospholamban multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLN mRNA CTD PMID:27935865 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pnma8b PNMA family member 8B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PNMA8B mRNA CTD PMID:27935865 NCBI chr 1:77,622,287...77,626,525
Ensembl chr 1:77,622,283...77,627,148 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP pioglitazone results in increased expression of POR mRNA CTD PMID:16597547 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
affects response to substance
affects binding
increases activity		 EXP
ISO		 pioglitazone binds to and results in increased activity of PPARA protein
NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA]; pioglitazone results in increased activity of [PPARA protein binds to RXRA protein]
pioglitazone results in increased expression of PPARA mRNA; pioglitazone results in increased expression of PPARA protein
PPARA protein affects the susceptibility to pioglitazone
pioglitazone binds to PPARA protein
pioglitazone results in increased activity of PPARA protein		 CTD PMID:11172467 PMID:11779144 PMID:15273253 PMID:16751799 PMID:19201410 More... NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding
increases expression
multiple interactions
increases activity		 ISO pioglitazone binds to PPARB protein; pioglitazone binds to PPARD protein
pioglitazone results in increased expression of PPARD mRNA
pioglitazone results in increased activity of [PPARD protein binds to RXRA protein]
pioglitazone results in increased activity of PPARD protein		 CTD PMID:11779144 PMID:19201410 PMID:23150725 PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
affects expression
affects response to substance
increases activity
increases expression
affects binding		 ISO
EXP		 [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Ethanol inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]; GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein]; Pioglitazone inhibits the reaction [GW 1929 binds to PPARG protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PPARG protein]; Pioglitazone promotes the reaction [PPARG protein binds to NPHS1 promoter]; Pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA]; Pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]; PPARG protein promotes the reaction [Pioglitazone results in increased activity of DIO2 protein]; Ro 41-5253 inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]
[ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [Dexamethasone co-treated with INS protein co-treated with pioglitazone] results in increased expression of PPARG protein; [pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone binds to and results in increased activity of PPARG protein; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron]; pioglitazone promotes the reaction [Toluene 2,4-Diisocyanate results in increased localization of PPARG protein]; pioglitazone results in increased activity of and results in decreased expression of PPARG protein; PPARG protein affects the reaction [pioglitazone results in increased expression of ADIPOQ mRNA]
pioglitazone affects the expression of PPARG; pioglitazone affects the expression of PPARG mRNA
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Diglycerides]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Phospholipids]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Triglycerides]; [Pioglitazone results in increased activity of PPARG protein] which results in decreased abundance of Triglycerides; [Pioglitazone results in increased activity of PPARG protein] which results in increased abundance of Diglycerides; Pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Cisplatin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Fructose results in decreased activity of PPARG protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG protein]
PPARG protein affects the susceptibility to pioglitazone
pioglitazone results in increased activity of PPARG protein
Pioglitazone results in increased expression of PPARG mRNA; Pioglitazone results in increased expression of PPARG mRNA alternative form; Pioglitazone results in increased expression of PPARG protein
pioglitazone results in increased expression of PPARG mRNA
Pioglitazone binds to PPARG protein
pioglitazone affects the expression of PPARG mRNA; pioglitazone affects the expression of PPARG protein		 CTD PMID:9836514 PMID:11172467 PMID:11779144 PMID:11991651 PMID:12055599 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
multiple interactions		 EXP
ISO		 pioglitazone results in decreased expression of PPARGC1A mRNA
Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARGC1A protein]		 CTD PMID:22456468 PMID:27366949 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppbp pro-platelet basic protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PPBP mRNA CTD PMID:27935865 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3A mRNA CTD PMID:27935865 NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3C mRNA CTD PMID:27935865 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha increases expression ISO Pioglitazone results in increased expression of PPP2CA mRNA CTD PMID:32589349 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression ISO Pioglitazone results in increased expression of PPP2R2B mRNA CTD PMID:32589349 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein] CTD PMID:26643070 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions
decreases expression		 ISO [Metformin co-treated with Pioglitazone] results in decreased expression of PRKCA mRNA
Pioglitazone results in decreased expression of PRKCA mRNA		 CTD PMID:32589349 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcg protein kinase C, gamma increases expression ISO Pioglitazone results in increased expression of PRKCG mRNA CTD PMID:32589349 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKCQ mRNA CTD PMID:27935865 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKG1 mRNA CTD PMID:27935865 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Prnp prion protein increases expression
multiple interactions		 ISO Pioglitazone results in increased expression of PRNP protein
GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PRNP protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PRNP protein]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]		 CTD PMID:29734669 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Prok2 prokineticin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PROK2 mRNA CTD PMID:27935865 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385 		JBrowse link
G Prr32 proline rich 32 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR32 mRNA CTD PMID:27935865 NCBI chr  X:123,978,010...123,979,928
Ensembl chr  X:123,977,985...123,979,942 		JBrowse link
G Prr33 proline rich 33 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR33 mRNA CTD PMID:27935865 NCBI chr 1:197,644,903...197,650,774
Ensembl chr 1:197,644,902...197,650,714 		JBrowse link
G Prxl2b peroxiredoxin like 2B decreases expression ISO Pioglitazone results in decreased expression of PRXL2B mRNA CTD PMID:30031879 NCBI chr 5:165,462,610...165,465,213 JBrowse link
G Psors1c2 psoriasis susceptibility 1 candidate 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PSORS1C2 mRNA CTD PMID:27935865 NCBI chr20:3,202,178...3,203,599
Ensembl chr20:3,202,174...3,203,599 		JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Pioglitazone results in increased expression of PTEN mRNA CTD PMID:32589349 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgfr prostaglandin F receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PTGFR mRNA CTD PMID:27935865 NCBI chr 2:240,731,185...240,766,674
Ensembl chr 2:240,733,375...240,765,650 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression		 EXP
ISO		 [Atorvastatin co-treated with Pioglitazone] results in increased expression of PTGS2 protein
pioglitazone results in decreased expression of PTGS2 mRNA
pioglitazone results in decreased expression of PTGS2 protein
Pioglitazone results in increased expression of PTGS2 mRNA		 CTD PMID:15817521 PMID:16386242 PMID:16908763 PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pvalb parvalbumin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PVALB mRNA CTD PMID:27935865 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Pxmp2 peroxisomal membrane protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PXMP2 mRNA CTD PMID:27935865 NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PYGM mRNA CTD PMID:27935865 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Ralyl RALY RNA binding protein-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RALYL mRNA CTD PMID:27935865 NCBI chr 2:87,482,747...88,274,329
Ensembl chr 2:87,482,755...88,274,452 		JBrowse link
G Ranbp2 RAN binding protein 2 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RANBP2 mRNA] CTD PMID:20847119 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481 		JBrowse link
G Rasd2 RASD family, member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASD2 mRNA CTD PMID:27935865 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rasl12 RAS-like, family 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASL12 mRNA CTD PMID:27935865 NCBI chr 8:65,917,840...65,931,885
Ensembl chr 8:65,917,840...65,932,741 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO pioglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rcan2 regulator of calcineurin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RCAN2 mRNA CTD PMID:27935865 NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856 		JBrowse link
G Rdh10 retinol dehydrogenase 10 increases expression ISO Pioglitazone results in increased expression of RDH10 mRNA CTD PMID:30031879 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Reep3 receptor accessory protein 3 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of REEP3 mRNA] CTD PMID:20847119 NCBI chr20:21,493,868...21,578,698
Ensembl chr20:21,493,954...21,578,697 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects expression		 ISO
EXP		 pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased localization of RELA protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone inhibits the reaction [Aldosterone results in increased activity of RELA protein]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA protein]
Pioglitazone affects the expression of RELA mRNA; Pioglitazone affects the expression of RELA protein		 CTD PMID:17015710 PMID:18660453 PMID:28744220 PMID:36988379 PMID:37044004 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retn resistin multiple interactions
increases expression
increases secretion		 ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of RETN mRNA; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of RETN mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased secretion of RETN protein]
Pioglitazone results in increased expression of RETN mRNA
Pioglitazone results in increased secretion of RETN protein		 CTD PMID:27918843 PMID:27935865 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Retsat retinol saturase multiple interactions
increases expression		 ISO [pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA
Pioglitazone results in increased expression of RETSAT mRNA; Pioglitazone results in increased expression of RETSAT protein		 CTD PMID:19139408 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310 		JBrowse link
G Rgcc regulator of cell cycle decreases expression ISO Pioglitazone results in decreased expression of RGCC mRNA CTD PMID:30031879 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Rgn regucalcin multiple interactions ISO Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]; Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]] CTD PMID:29734669 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 decreases expression ISO Pioglitazone results in decreased expression of RGS1 mRNA CTD PMID:30031879 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS13 mRNA CTD PMID:27935865 NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS5 mRNA CTD PMID:27935865 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Rgs7bp regulator of G-protein signaling 7 binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS7BP mRNA CTD PMID:27935865 NCBI chr 2:36,133,944...36,231,505
Ensembl chr 2:36,139,201...36,231,505 		JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression ISO Pioglitazone results in increased expression of RHEB mRNA CTD PMID:32589349 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of RICTOR mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RICTOR mRNA] CTD PMID:20847119 PMID:32589349 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Riox1 ribosomal oxygenase 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RIOX1 mRNA CTD PMID:20847119 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
G Rnase6 ribonuclease A family member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RNASE6 mRNA CTD PMID:27935865 NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328 		JBrowse link
G Robo3 roundabout guidance receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ROBO3 mRNA CTD PMID:27935865 NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315 		JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO pioglitazone results in increased expression of RORC mRNA CTD PMID:9543393 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Rpl3l ribosomal protein L3-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RPL3L mRNA CTD PMID:27935865 NCBI chr10:13,753,914...13,764,458
Ensembl chr10:13,753,886...13,764,457 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
multiple interactions
decreases expression		 ISO pioglitazone results in decreased phosphorylation of RPS6 protein
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]
Pioglitazone results in decreased expression of RPS6 mRNA		 CTD PMID:26643070 PMID:32589349 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 increases expression ISO Pioglitazone results in increased expression of RPS6KA1 mRNA CTD PMID:32589349 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression
multiple interactions		 ISO Pioglitazone results in increased expression of RPS6KA2 mRNA
[Metformin co-treated with Pioglitazone] results in increased expression of RPS6KA2 mRNA		 CTD PMID:32589349 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of RPS6KA5 mRNA CTD PMID:32589349 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation		 ISO pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein]
pioglitazone results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:26643070 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 increases phosphorylation
multiple interactions		 ISO pioglitazone results in increased phosphorylation of RPTOR protein
PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein]		 CTD PMID:26643070 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Rpusd2 RNA pseudouridine synthase domain containing 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RPUSD2 mRNA CTD PMID:20847119 NCBI chr 3:106,017,759...106,023,010
Ensembl chr 3:106,017,864...106,023,251 		JBrowse link
G Rspo1 R-spondin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RSPO1 mRNA CTD PMID:27935865 NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933 		JBrowse link
G Rtl3 retrotransposon Gag like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTL3 mRNA CTD PMID:27935865 NCBI chr  X:71,947,343...71,951,008
Ensembl chr  X:71,948,253...71,950,121 		JBrowse link
G Rtn2 reticulon 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTN2 mRNA CTD PMID:27935865 NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RUNX1T1 mRNA CTD PMID:27935865 NCBI chr 5:27,187,674...27,338,070
Ensembl chr 5:27,187,551...27,335,592 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO pioglitazone results in increased activity of [PPARA protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARD protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein] CTD PMID:11779144 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RYR1 mRNA CTD PMID:27935865 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression
decreases expression		 ISO [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A8 mRNA
pioglitazone results in increased expression of S100A8 mRNA
Pioglitazone results in decreased expression of S100A8 mRNA		 CTD PMID:28138970 PMID:28263783 PMID:30031879 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of S100A9 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A9 mRNA
pioglitazone results in increased expression of S100A9 mRNA		 CTD PMID:27935865 PMID:28138970 PMID:28263783 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sbk2 SH3 domain binding kinase family, member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK2 mRNA CTD PMID:27935865 NCBI chr 1:68,874,081...68,881,918
Ensembl chr 1:68,874,152...68,881,916 		JBrowse link
G Sbk3 SH3 domain binding kinase family, member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK3 mRNA CTD PMID:27935865 NCBI chr 1:68,867,847...68,873,249
Ensembl chr 1:68,868,238...68,871,392 		JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBSPON mRNA CTD PMID:27935865 NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO pioglitazone results in decreased expression of SCARB1 mRNA CTD PMID:20503262 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA] CTD PMID:32613381 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCGB3A2 mRNA CTD PMID:27935865 NCBI chr18:35,932,840...35,935,762
Ensembl chr18:35,932,840...35,935,762 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN2A mRNA CTD PMID:27935865 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4A mRNA CTD PMID:27935865 NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545 		JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4B mRNA CTD PMID:27935865 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN7A mRNA CTD PMID:27935865 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron]
pioglitazone results in increased expression of SCNN1G mRNA		 CTD PMID:16007095 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCUBE1 mRNA CTD PMID:27935865 NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940 		JBrowse link
G Sec31b SEC31 homolog B, COPII coat complex component multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SEC31B mRNA CTD PMID:27935865 NCBI chr 1:243,376,283...243,404,557
Ensembl chr 1:243,378,456...243,404,557 		JBrowse link
G Sele selectin E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELE mRNA CTD PMID:27935865 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Selp selectin P multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELP mRNA CTD PMID:27935865 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression		 EXP
ISO		 pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA]
pioglitazone results in increased expression of SERPINE1 mRNA		 CTD PMID:16598202 PMID:21757225 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP2 mRNA CTD PMID:27935865 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP4 mRNA CTD PMID:27935865 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFTPA1 mRNA CTD PMID:27935865 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sgca sarcoglycan, alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCA mRNA CTD PMID:27935865 NCBI chr10:79,904,698...79,922,808
Ensembl chr10:79,908,738...79,922,813 		JBrowse link
G Sgce sarcoglycan, epsilon multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCE mRNA CTD PMID:27935865 NCBI chr 4:32,771,477...32,842,238
Ensembl chr 4:32,771,477...32,842,254 		JBrowse link
G Sgcg sarcoglycan, gamma multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCG mRNA CTD PMID:27935865 NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Pioglitazone results in decreased expression of SGK1 mRNA CTD PMID:32589349 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sh2d5 SH2 domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SH2D5 mRNA CTD PMID:27935865 NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955 		JBrowse link
G Sh2d7 SH2 domain containing 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SH2D7 mRNA CTD PMID:27935865 NCBI chr 8:54,918,399...54,930,129
Ensembl chr 8:54,918,406...54,929,726 		JBrowse link
G She Src homology 2 domain containing E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SHE mRNA CTD PMID:27935865 NCBI chr 2:175,262,431...175,287,807
Ensembl chr 2:175,262,442...175,286,669 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC17A8 mRNA CTD PMID:27935865 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO pioglitazone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc25a24 solute carrier family 25 member 24 decreases expression ISO Pioglitazone results in decreased expression of SLC25A24 mRNA CTD PMID:30031879 NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231 		JBrowse link
G Slc25a34 solute carrier family 25, member 34 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A34 mRNA CTD PMID:27935865 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Slc25a53 solute carrier family 25, member 53 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A53 mRNA CTD PMID:27935865 NCBI chr  X:100,306,917...100,319,662
Ensembl chr  X:100,306,915...100,319,863 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC26A7 mRNA CTD PMID:27935865 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO pioglitazone results in increased expression of SLC27A1 mRNA CTD PMID:20723549 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of SLC2A3 mRNA CTD PMID:20847119 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA] CTD PMID:27350165 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions
decreases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC2A5 mRNA
Pioglitazone results in decreased expression of SLC2A5 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106 		JBrowse link
G Slc2a6 solute carrier family 2 member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC2A6 mRNA CTD PMID:27935865 NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208 		JBrowse link
G Slc38a5 solute carrier family 38, member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC38A5 mRNA CTD PMID:27935865 NCBI chr  X:14,213,727...14,222,498
Ensembl chr  X:14,213,729...14,222,498 		JBrowse link
G Slc4a5 solute carrier family 4 member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC4A5 mRNA CTD PMID:27935865 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC5A7 mRNA CTD PMID:27935865 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC6A12 mRNA CTD PMID:27935865 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A15 mRNA CTD PMID:27935865 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Slc6a17 solute carrier family 6 member 17 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A17 mRNA CTD PMID:27935865 NCBI chr 2:195,107,434...195,155,697
Ensembl chr 2:195,107,438...195,155,697 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Pioglitazone results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO pioglitazone affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Pioglitazone affects the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO4C1 mRNA CTD PMID:27935865 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO5A1 mRNA CTD PMID:27935865 NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913 		JBrowse link
G Slit1 slit guidance ligand 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLIT1 mRNA CTD PMID:27935865 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Sln sarcolipin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLN mRNA CTD PMID:27935865 NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791 		JBrowse link
G Sltm SAFB-like, transcription modulator multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of SLTM mRNA] CTD PMID:20847119 NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825 		JBrowse link
G Smad9 SMAD family member 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMAD9 mRNA CTD PMID:27935865 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Smim10l2a small integral membrane protein 10 like 2A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of SMIM10L2A mRNA CTD PMID:27935865 NCBI chr  X:134,151,325...134,154,647 JBrowse link
G Smoc1 SPARC related modular calcium binding 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMOC1 mRNA CTD PMID:27935865 NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699 		JBrowse link
G Smpx small muscle protein, X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMPX mRNA CTD PMID:27935865 NCBI chr  X:37,233,209...37,292,266
Ensembl chr  X:37,234,294...37,276,708 		JBrowse link
G Smtnl1 smoothelin-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMTNL1 mRNA CTD PMID:27935865 NCBI chr 3:69,889,010...69,901,096
Ensembl chr 3:69,889,010...69,901,079 		JBrowse link
G Sncaip synuclein, alpha interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SNCAIP mRNA CTD PMID:27935865 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions		 ISO pioglitazone results in increased expression of SOD1 mRNA; pioglitazone results in increased expression of SOD1 protein
pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA]		 CTD PMID:11172467 PMID:18513333 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 affects activity ISO pioglitazone affects the activity of SOD2 protein CTD PMID:21962020 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sorcs1 sortilin-related VPS10 domain containing receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SORCS1 mRNA CTD PMID:27935865 NCBI chr 1:249,080,662...249,594,520
Ensembl chr 1:249,081,355...249,594,507 		JBrowse link
G Sowahc sosondowah ankyrin repeat domain family member C increases expression ISO Pioglitazone results in increased expression of SOWAHC mRNA CTD PMID:30031879 NCBI chr20:27,195,198...27,199,664
Ensembl chr20:27,193,743...27,265,018
Ensembl chr20:27,193,743...27,265,018 		JBrowse link
G Sox10 SRY-box transcription factor 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX10 mRNA CTD PMID:27935865 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Sox8 SRY-box transcription factor 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX8 mRNA CTD PMID:27935865 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847 		JBrowse link
G Sparcl1 SPARC like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPARCL1 mRNA CTD PMID:27935865 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865 		JBrowse link
G Speg striated muscle enriched protein kinase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPEG mRNA CTD PMID:27935865 NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144 		JBrowse link
G Spink9 serine peptidase inhibitor, Kazal type 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPINK12 mRNA CTD PMID:27935865 NCBI chr18:36,427,043...36,430,271
Ensembl chr18:36,426,989...36,430,271 		JBrowse link
G Spocd1 SPOC domain containing 1 increases expression ISO Pioglitazone results in increased expression of SPOCD1 mRNA CTD PMID:30031879 NCBI chr 5:142,288,822...142,297,113 JBrowse link
G Spon1 spondin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPON1 mRNA CTD PMID:27935865 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein] CTD PMID:16979161 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sprr1b small proline-rich protein 1B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR1B mRNA CTD PMID:27935865 NCBI chr 2:178,008,844...178,010,742
Ensembl chr 2:178,009,130...178,009,567 		JBrowse link
G Sprr2a small proline rich protein 2A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2H mRNA CTD PMID:27935865 NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236 		JBrowse link
G Sprr2b small proline rich protein 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2B mRNA CTD PMID:27935865 NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096 		JBrowse link
G Sprr2d small proline-rich protein 2D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2D mRNA CTD PMID:27935865 NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679 		JBrowse link
G Sprr2f small proline rich protein 2F multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2F mRNA CTD PMID:27935865 NCBI chr 2:177,989,974...177,990,204
Ensembl chr 2:177,989,974...177,990,204 		JBrowse link
G Srl sarcalumenin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRL mRNA CTD PMID:27935865 NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRPX mRNA CTD PMID:27935865 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ST3GAL1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ST3GAL1 mRNA] CTD PMID:20847119 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STAC3 mRNA CTD PMID:27935865 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589 		JBrowse link
G Stk11 serine/threonine kinase 11 increases expression ISO Pioglitazone results in increased expression of STK11 mRNA CTD PMID:32589349 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stx1b syntaxin 1B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STX1B mRNA CTD PMID:27935865 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Styxl2 serine/threonine/tyrosine interacting like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of STYXL2 mRNA CTD PMID:27935865 NCBI chr13:78,349,361...78,378,480
Ensembl chr13:78,349,365...78,378,458 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of SULT1C2 mRNA CTD PMID:27935865 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SULT1C1 mRNA CTD PMID:27935865 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030 		JBrowse link
G Susd5 sushi domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SUSD5 mRNA CTD PMID:27935865 NCBI chr 8:113,996,771...114,036,133
Ensembl chr 8:113,997,362...114,035,861 		JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVEP1 mRNA CTD PMID:27935865 NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525 		JBrowse link
G Svopl SVOP like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVOPL mRNA CTD PMID:27935865 NCBI chr 4:66,697,550...66,751,699
Ensembl chr 4:66,698,177...66,758,978 		JBrowse link
G Syn1 synapsin I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SYN1 mRNA CTD PMID:27935865 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Syn2 synapsin II multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SYN2 protein] CTD PMID:32735850 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192 		JBrowse link
G Synpo2 synaptopodin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYNPO2 mRNA CTD PMID:27935865 NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267 		JBrowse link
G Sypl2 synaptophysin-like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYPL2 mRNA CTD PMID:27935865 NCBI chr 2:195,849,062...195,863,794
Ensembl chr 2:195,849,062...195,863,794 		JBrowse link
G Tagln transgelin multiple interactions
decreases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAGLN mRNA
Pioglitazone results in decreased expression of TAGLN mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TARM1 mRNA CTD PMID:27935865 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Tas2r108 taste receptor, type 2, member 108 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAS2R108 mRNA CTD PMID:27935865 NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:69,287,667...69,288,581 		JBrowse link
G Tbx15 T-box transcription factor 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX15 mRNA CTD PMID:27935865 NCBI chr 2:186,576,650...186,687,748
Ensembl chr 2:186,576,676...186,687,663 		JBrowse link
G Tbx4 T-box transcription factor 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX4 mRNA CTD PMID:27935865 NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825 		JBrowse link
G Tcap titin-cap multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCAP mRNA CTD PMID:27935865 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Tceal7 transcription elongation factor A like 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCEAL7 mRNA CTD PMID:27935865 NCBI chr  X:99,228,405...99,230,551
Ensembl chr  X:99,228,458...99,230,543 		JBrowse link
G Tdh L-threonine dehydrogenase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TDH mRNA CTD PMID:27935865 NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TDO2 mRNA CTD PMID:27935865 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Telo2 telomere maintenance 2 increases expression
multiple interactions		 ISO Pioglitazone results in increased expression of TELO2 mRNA
[Metformin co-treated with Pioglitazone] results in increased expression of TELO2 mRNA		 CTD PMID:32589349 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TET1 mRNA CTD PMID:27935865 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression ISO pioglitazone results in decreased expression of TFAM mRNA CTD PMID:20860658 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tff2 trefoil factor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TFF2 mRNA CTD PMID:27935865 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Tg thyroglobulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TG mRNA CTD PMID:27935865 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression		 ISO
EXP		 pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TGFB1 protein]
pioglitazone results in decreased expression of TGFB1 mRNA
pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]
Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]		 CTD PMID:12055599 PMID:16484506 PMID:16611854 PMID:17015710 PMID:32613381 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgm7 transglutaminase 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TGM7 mRNA CTD PMID:27935865 NCBI chr 3:108,051,890...108,068,116
Ensembl chr 3:108,051,890...108,076,239 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein] CTD PMID:17063547 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of THRSP mRNA CTD