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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zoxamide
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Accession:CHEBI:82048 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-zoxamide. A fungicide used for the control of various fungal infections including blight in potatoes and tomatoes.
Synonyms:exact_synonym: rac-3,5-dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide
 related_synonym: (RS)-3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide;   (RS)-zoxamide;   3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide;   3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methylbenzamide;   rac-zoxamide;   racemic zoxamide
 xref: CAS:156052-68-5;   KEGG:C18903
 xref_mesh: MESH:C451427
 xref: PMID:20001673;   PMID:21692644;   PMID:22424065;   PMID:23380566;   PMID:24552297;   PMID:24586697;   PMID:25052524;   Pesticides:zoxamide;   Reaxys:11342942


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zoxamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Sulfur co-treated with zoxamide co-treated with cyflufenamid] results in decreased expression of BAX mRNA; [Sulfur co-treated with zoxamide co-treated with metrafenone] results in decreased expression of BAX mRNA CTD PMID:35564597 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Sulfur co-treated with zoxamide co-treated with metrafenone] results in decreased expression of BCL2 mRNA CTD PMID:35564597 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO zoxamide results in decreased activity of DIO1 protein CTD PMID:29228274 PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO zoxamide results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO zoxamide results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [Sulfur co-treated with zoxamide co-treated with metrafenone] results in decreased expression of NFE2L2 mRNA CTD PMID:35564597 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO zoxamide affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      chemical substance 14394
        mixture 13711
          racemate 12088
            zoxamide 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      carboacyl group 17694
                                        univalent carboacyl group 17694
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              monocarboxylic acid amide 15727
                                                arenecarboxamide 8254
                                                  benzamides 8254
                                                    3,5-dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide 7
                                                      (S)-zoxamide 7
                                                        zoxamide 7
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