CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: sulfluramid
Accession: CHEBI:81945
browse the term
Definition: A sulfonamide obtained by the formal condensation of perfluorooctane-1-sulfonic acid with ethylamine.
Synonyms: exact_synonym: N-ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
related_synonym: Formula=C10H6F17NO2S; InChI=1S/C10H6F17NO2S/c1-2-28-31(29,30)10(26,27)8(21,22)6(17,18)4(13,14)3(11,12)5(15,16)7(19,20)9(23,24)25/h28H,2H2,1H3; InChIKey=CCEKAJIANROZEO-UHFFFAOYSA-N; N-Ethylperfluorooctylsulfonamide; N-ethylperfluorooctane-1-sulfonamide; SMILES=CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
xref: CAS:4151-50-2; KEGG:C18766
xref_mesh: MESH:C063732
xref: PMID:1495031; PMID:15713031; PMID:1673400; PMID:2324377; PPDB:602; Pesticides:sulfluramid; Reaxys:2317462
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Abca1
ATP binding cassette subfamily A member 1
increases expression
ISO
sulfluramid results in increased expression of ABCA1 mRNA
CTD
PMID:35337807
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Acot2
acyl-CoA thioesterase 2
increases expression
ISO
sulfluramid results in increased expression of ACOT2 mRNA
CTD
PMID:35337807
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
sulfluramid results in increased expression of CYP2B6 mRNA
CTD
PMID:35337807
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
sulfluramid results in increased expression of CYP7A1 mRNA
CTD
PMID:35337807
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
increases expression
ISO
sulfluramid results in increased expression of EHHADH mRNA
CTD
PMID:35337807
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Fasn
fatty acid synthase
increases expression
ISO
sulfluramid results in increased expression of FASN mRNA
CTD
PMID:35337807
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
increases expression
ISO
sulfluramid results in increased expression of GPAM mRNA
CTD
PMID:35337807
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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Gsta1
glutathione S-transferase alpha 1
increases expression
ISO
sulfluramid results in increased expression of GSTA1 mRNA
CTD
PMID:35337807
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
sulfluramid results in increased expression of HMGCS1 mRNA
CTD
PMID:35337807
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Mttp
microsomal triglyceride transfer protein
increases expression
ISO
sulfluramid results in increased expression of MTTP mRNA
CTD
PMID:35337807
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
sulfluramid results in increased expression of NFE2L2 mRNA
CTD
PMID:35337807
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
sulfluramid results in increased expression of NQO1 mRNA
CTD
PMID:35337807
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases expression
ISO
sulfluramid results in increased expression of NR1I2 mRNA
CTD
PMID:35337807
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases expression
ISO
sulfluramid results in increased expression of NR1I3 mRNA
CTD
PMID:35337807
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
increases expression
ISO
sulfluramid results in increased expression of PCK2 mRNA
CTD
PMID:35337807
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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Ppara
peroxisome proliferator activated receptor alpha
increases expression affects binding
ISO
sulfluramid results in increased expression of PPARA mRNA sulfluramid binds to PPARA protein
CTD
PMID:35337807 PMID:35752307
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression affects binding
ISO EXP
sulfluramid results in increased expression of PPARG mRNA sulfluramid binds to PPARG protein
CTD
PMID:35337807 PMID:35752307
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Scd
stearoyl-CoA desaturase
increases expression
ISO
sulfluramid results in increased expression of SCD mRNA
CTD
PMID:35337807
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Slc27a1
solute carrier family 27 member 1
increases expression
ISO
sulfluramid results in increased expression of SLC27A1 mRNA
CTD
PMID:35337807
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Sod1
superoxide dismutase 1
increases expression
ISO
sulfluramid results in increased expression of SOD1 mRNA
CTD
PMID:35337807
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
ISO
sulfluramid results in increased expression of SREBF1 mRNA
CTD
PMID:35337807
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Sult2a1
sulfotransferase family 2A member 1
increases expression
ISO
sulfluramid results in increased expression of SULT2A1 mRNA
CTD
PMID:35337807
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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