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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:metiram
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Accession:CHEBI:81539 term browser browse the term
Definition:A polymer comprising ethylenebis(dithiocarbamate) units and (ammonia)zinc(II). It is used in agriculture for the control of scab in fruit, blight in tomatoes and potatoes, and downy mildew in hops and grapes.
Synonyms:related_synonym: Amarex;   Polyram 80;   metirame;   metirame zinc;   zinc ammoniate ethylenebis(dithiocarbamate)-poly(ethylenethiuram disulfide);   zinc metiram
 xref: CAS:9006-42-2
 xref_mesh: MESH:C008971
 xref: Pesticides:metiram;   Reaxys:11316510;   kegg.compound:C18144;   pubmed:10774831;   pubmed:21544926;   pubmed:22555811
 chemrof_formula: (C16H30N11S16Zn3)n
 chemrof_smiles: *SC(=S)NCCNC(=S)[S][Zn]([NH2])[S]C(=S)NCCNC(=S)[S][Zn]([NH2])[S]C(=S)NCCNC(=S)[S][Zn]([NH2])[S]C(=S)NCCNC(=S)S*



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metiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 protein CTD PMID:32800223 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC1 mRNA CTD PMID:32800223 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC2 mRNA CTD PMID:32800223 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 protein CTD PMID:32800223 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX protein CTD PMID:32800223 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BBC3 mRNA CTD PMID:32800223 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein CTD PMID:32800223 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BIRC2 mRNA CTD PMID:32800223 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein CTD PMID:32800223 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein CTD PMID:32800223 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CYCS mRNA CTD PMID:32800223 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of GSTM1 mRNA CTD PMID:32800223 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
JBrowse link
G Hdac3 histone deacetylase 3 decreases activity ISO polymarcine results in decreased activity of HDAC3 protein CTD PMID:21251949 NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025
JBrowse link
G Hdac6 histone deacetylase 6 decreases activity ISO polymarcine results in decreased activity of HDAC6 protein CTD PMID:21251949 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370
JBrowse link
G Mvp major vault protein multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of MVP mRNA CTD PMID:32800223 NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of PMAIP1 mRNA CTD PMID:32800223 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
JBrowse link
G Sirt1 sirtuin 1 decreases activity ISO polymarcine results in decreased activity of SIRT1 protein CTD PMID:21251949 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Sirt2 sirtuin 2 decreases activity ISO polymarcine results in decreased activity of SIRT2 protein CTD PMID:21251949 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
JBrowse link
G Sirt3 sirtuin 3 decreases activity ISO polymarcine results in decreased activity of SIRT3 protein CTD PMID:21251949 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO polymarcine inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine] CTD PMID:27979590 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNF mRNA CTD PMID:32800223 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TNFRSF10A mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNFRSF10A mRNA CTD PMID:32800223 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TP53 mRNA CTD PMID:32800223 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of XIAP mRNA CTD PMID:32800223 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        pesticide 18454
          antifungal agrochemical 11980
            metiram 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic ion 11556
                              organic anion 6893
                                organic sulfur anion 5125
                                  dithiocarbamate anions 5125
                                    dithiocarbamate salt 1076
                                      metiram 24
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