2,3',4,4',5-Pentachlorobiphenyl - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	2,3',4,4',5-Pentachlorobiphenyl	go back to main search page
Accession:	CHEBI:81520	browse the term
Definition:	A pentachlorobiphenyl that has formula C12H5Cl5.
Synonyms:	related_synonym:	Formula=C12H5Cl5; InChI=1S/C12H5Cl5/c13-8-2-1-6(3-10(8)15)7-4-11(16)12(17)5-9(7)14/h1-5H; InChIKey=IUTPYMGCWINGEY-UHFFFAOYSA-N; PCB 118; SMILES=Clc1ccc(cc1Cl)-c1cc(Cl)c(Cl)cc1Cl
	xref:	CAS:31508-00-6; KEGG:C18118
	xref_mesh:	MESH:C070055

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Genes (1226)

2,3',4,4',5-Pentachlorobiphenyl

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of PZP mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

aminoadipate-semialdehyde synthase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

4-aminobutyrate aminotransferase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ABAT mRNA

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily C member 3

multiple interactions

[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

abhydrolase domain containing 12, lysophospholipase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABHD12 mRNA

NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564

G

abhydrolase domain containing 13

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABHD13 mRNA

NCBI chr16:79,501,879...79,516,712
Ensembl chr16:79,501,727...79,516,748

G

abhydrolase domain containing 16B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABHD16B mRNA

NCBI chr 3:168,594,677...168,596,574
Ensembl chr 3:168,594,609...168,619,762

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABHD4 mRNA

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

abl-interactor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABI1 mRNA

NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABO mRNA

NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423

G

activator of basal transcription 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABT1 mRNA

NCBI chr17:41,699,151...41,701,253
Ensembl chr17:41,699,147...41,701,259

G

ankyrin repeat and BTB domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ABTB2 mRNA

NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548

G

acetyl-CoA carboxylase alpha

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ACACA mRNA

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA binding domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACBD3 mRNA

NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380

G

alkaline ceramidase 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ACER1 mRNA

NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434

G

apoptotic chromatin condensation inducer 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACIN1 mRNA

NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001

G

actin, beta

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin, gamma 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACTG1 mRNA

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

G

actinin alpha 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ACTN2 mRNA

NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622

G

actinin alpha 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACTN4 mRNA

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

G

aminoacylase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACY3 mRNA

NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175

G

acylphosphatase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ACYP2 mRNA

NCBI chr14:104,201,894...104,371,415
Ensembl chr14:104,201,895...104,371,386

G

ADAM metallopeptidase domain 10

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADAM10 mRNA

NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889

G

ADAM metallopeptidase domain 23

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADAM23 mRNA

NCBI chr 9:64,862,649...65,009,718
Ensembl chr 9:64,862,878...65,006,515

G

ADAM metallopeptidase with thrombospondin type 1 motif, 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADAMTS6 mRNA

NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298

G

adhesion G protein-coupled receptor G1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADGRG1 mRNA

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADGRG2 mRNA

NCBI chr X:34,297,402...34,422,590
Ensembl chr X:34,297,402...34,422,609

G

ADP-ribosylarginine hydrolase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ADPRH mRNA

NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931

G

actin filament associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

actin filament associated protein 1-like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AFAP1L1 mRNA

NCBI chr18:55,183,786...55,244,174
Ensembl chr18:55,183,786...55,244,146

G

AFG3 like matrix AAA peptidase subunit 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AFG3L2 mRNA

NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110

G

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AGL mRNA

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

agouti related neuropeptide

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AGRP mRNA

NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584

G

adenosylhomocysteinase-like 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AHCYL2 mRNA

NCBI chr 4:58,381,290...58,531,061
Ensembl chr 4:58,381,218...58,531,060

G

aryl hydrocarbon receptor

multiple interactions
increases activity
increases expression

2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYBB mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF4 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM protein]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]
2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]
2,3',4,4',5-pentachlorobiphenyl results in increased activity of AHR protein
2,3',4,4',5-pentachlorobiphenyl binds to and results in increased activity of AHR protein
2,3',4,4',5-pentachlorobiphenyl results in increased expression of AHR mRNA

PMID:10448124 PMID:12850102 PMID:20961953 PMID:21781905 PMID:25654323 More...

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aryl-hydrocarbon receptor repressor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AHRR mRNA

NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673

G

aryl-hydrocarbon receptor-interacting protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AIP mRNA

NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122

G

A-kinase anchoring protein 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AKAP8 mRNA

NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399

G

A-kinase anchoring protein 8 like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AKAP8L mRNA

NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275

G

akirin 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AKIRIN2 mRNA

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

G

AKT serine/threonine kinase 1

increases expression
multiple interactions

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AKT1 mRNA
2,3',4,4',5-pentachlorobiphenyl results in increased expression of and results in increased phosphorylation of AKT1 protein; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aldehyde dehydrogenase 3 family, member A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ALDH3A1 mRNA

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

alkB homolog 5, RNA demethylase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ALKBH5 mRNA

NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331

G

autophagy and beclin 1 regulator 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AMBRA1 mRNA

NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221

G

ankyrin repeat domain 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ANKRD12 mRNA

NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911

G

ankyrin repeat domain 13a

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ANKRD13A mRNA

NCBI chr12:41,798,196...41,828,327
Ensembl chr12:41,798,199...41,829,327

G

ankyrin repeat domain 31

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ANKRD31 mRNA

NCBI chr 2:28,079,187...28,241,722
Ensembl chr 2:28,092,882...28,241,719

G

ankyrin repeat domain 35

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ANKRD35 mRNA

NCBI chr 2:184,207,076...184,227,063
Ensembl chr 2:184,207,071...184,227,063

G

ankyrin repeat domain 39

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ANKRD39 mRNA

NCBI chr 9:38,780,291...38,790,177
Ensembl chr 9:38,781,785...38,790,201

G

ankyrin repeat domain 65

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ANKRD65 mRNA

NCBI chr 5:166,398,359...166,400,616
Ensembl chr 5:166,397,748...166,400,953

G

anoctamin 4

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ANO4 mRNA

NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434

G

annexin A4

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ANXA4 mRNA

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

acyloxyacyl hydrolase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of AOAH mRNA

NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148

G

adaptor related protein complex 3 subunit beta 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of AP3B2 mRNA

NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191

G

adaptor related protein complex 3 subunit sigma 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AP3S1 mRNA

NCBI chr18:39,462,728...39,531,622
Ensembl chr18:39,462,765...39,531,622

G

adaptor related protein complex 4 subunit sigma 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AP4S1 mRNA

NCBI chr 6:69,133,403...69,174,488
Ensembl chr 6:69,133,373...69,175,496

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of APEX1 mRNA

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

apurinic/apyrimidinic endodeoxyribonuclease 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of APEX2 mRNA

NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439

G

amyloid beta precursor protein binding protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of APPBP2 mRNA

NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835

G

aprataxin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of APTX mRNA

NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855

G

androgen receptor

multiple interactions

2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; 2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]

PMID:18324785 PMID:21357386 PMID:26022396

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

ARB2 cotranscriptional regulator A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARB2A mRNA

NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162

G

ADP-ribosylation factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARF2 mRNA

NCBI chr10:88,867,836...88,889,654
Ensembl chr10:88,867,836...88,889,659

G

ARF GTPase 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARF6 mRNA

NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114

G

Rho GTPase activating protein 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGAP12 mRNA

NCBI chr17:51,588,810...51,702,417
Ensembl chr17:51,588,842...51,702,080

G

Rho GTPase activating protein 15

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGAP15 mRNA

NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265

G

Rho GTPase activating protein 18

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ARHGAP18 mRNA

NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256

G

Rho GTPase activating protein 21

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGAP21 mRNA

NCBI chr17:83,348,673...83,472,202
Ensembl chr17:83,348,673...83,472,444

G

Rho GTPase activating protein 24

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGAP24 mRNA

NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823

G

Rho GTPase activating protein 32

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ARHGAP32 mRNA

NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454

G

Rho GTPase activating protein 39

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGAP39 mRNA

NCBI chr 7:108,446,280...108,538,875
Ensembl chr 7:108,446,282...108,538,831

G

Rho/Rac guanine nucleotide exchange factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGEF2 mRNA

NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355

G

Rho guanine nucleotide exchange factor 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARHGEF3 mRNA

NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945

G

AT-rich interaction domain 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARID2 mRNA

NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512

G

ARF like GTPase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

ARF like GTPase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARL2 mRNA

NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

actin related protein 2/3 complex, subunit 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARPC3 mRNA

NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651

G

actin related protein 2/3 complex, subunit 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARPC5 mRNA

NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410

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ARVCF, delta catenin family member

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARVCF mRNA

NCBI chr11:82,588,137...82,645,832
Ensembl chr11:82,587,881...82,645,805

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ASAP3 mRNA

NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073

G

anti-silencing function 1B histone chaperone

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ASF1B mRNA

NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549

G

astacin like metalloendopeptidase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ASTL mRNA

NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868

G

ASXL transcriptional regulator 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ASXL2 mRNA

NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477

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ATPase family, AAA domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATAD1 mRNA

NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548

G

ATCAY kinesin light chain interacting caytaxin

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ATCAY mRNA

NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663

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activating transcription factor 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATF4 mRNA

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 7

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ATF7 mRNA

NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848

G

autophagy related 101

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG101 mRNA

NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633

G

autophagy related 14

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG14 mRNA

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

G

autophagy related 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG2B mRNA

NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015

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autophagy related 9A

multiple interactions
increases expression

1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG9A protein]
2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG9A mRNA; 2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATG9A protein

NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986

G

atlastin GTPase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATL3 mRNA

NCBI chr 1:204,680,958...204,727,360
Ensembl chr 1:204,680,968...204,723,354

G

ATPase 13A3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP13A3 mRNA

NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235

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ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP2A2 mRNA

NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101

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ATPase plasma membrane Ca2+ transporting 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP2B1 mRNA

NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295

G

ATP synthase F1 subunit epsilon

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ATP5F1E mRNA

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATP synthase inhibitory factor subunit 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP5IF1 mRNA

NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668

G

ATP synthase membrane subunit e

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ATP5ME mRNA

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

ATPase H+ transporting accessory protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP6AP2 mRNA

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

ATPase H+ transporting V0 subunit D1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATP6V0D1 mRNA

NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450

G

attractin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATRN mRNA

NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322

G

attractin like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATRNL1 mRNA

NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197

G

ATRX, chromatin remodeler

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ATRX mRNA

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

aurora kinase C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AURKC mRNA

NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386

G

arginine vasopressin-induced 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of AVPI1 mRNA

NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154

G

arginine vasopressin receptor 1A

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of AVPR1A mRNA

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

G

BTB domain and CNC homolog 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BACH1 mRNA

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

Bardet-Biedl syndrome 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BBS9 mRNA

NCBI chr 8:21,013,865...21,437,934
Ensembl chr 8:21,013,944...21,437,930

G

beclin 1

multiple interactions
increases expression

1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of BECN1 protein]

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

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beaded filament structural protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BFSP1 mRNA

NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337

G

BICD cargo adaptor 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of BICD1 mRNA

NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434

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BICD family like cargo adaptor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BICDL1 mRNA

NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130

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BCL2-interacting killer

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

basic helix-loop-helix ARNT like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BMAL1 mRNA

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 15

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BMP15 mRNA

NCBI chr X:16,169,123...16,174,187
Ensembl chr X:16,169,123...16,174,187

G

BMP-2 inducible kinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BMP2K mRNA

NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134

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bone morphogenetic protein 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BMP5 mRNA

NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925

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bone morphogenetic protein 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

G

biorientation of chromosomes in cell division 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BOD1 mRNA

NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787

G

bolA family member 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BOLA1 mRNA

NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576

G

BMP/retinoic acid inducible neural specific 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BRINP1 mRNA

NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150

G

BRCA1 interacting DNA helicase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BRIP1 mRNA

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

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BRICK1 subunit of SCAR/WAVE actin nucleating complex

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BRK1 mRNA

NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856

G

BSD domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of BSDC1 mRNA

NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092

G

C1GALT1-specific chaperone 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of C1GALT1C1 mRNA

NCBI chr X:117,378,123...117,382,620
Ensembl chr X:117,375,525...117,382,787

G

complement C1q B chain

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

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complement C1q binding protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of C1QBP mRNA

NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649

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calcium voltage-gated channel auxiliary subunit alpha2delta 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CACNA2D1 mRNA

NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969

G

cactin, spliceosome C complex subunit

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CACTIN mRNA

NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829

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calcium dependent secretion activator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CADPS mRNA

NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779

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calneuron 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CALN1 mRNA

NCBI chr12:25,811,743...26,303,670
Ensembl chr12:25,819,628...26,303,344

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calcium/calmodulin-dependent protein kinase ID

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CAMK1D mRNA

NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556

G

calmodulin regulated spectrin-associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAMSAP1 mRNA

NCBI chr 3:8,746,176...8,806,067
Ensembl chr 3:8,746,176...8,806,072

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calmodulin regulated spectrin-associated protein family, member 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAMSAP2 mRNA

NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597

G

calmodulin binding transcription activator 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAMTA1 mRNA

NCBI chr 5:161,510,283...162,356,902
Ensembl chr 5:161,510,283...162,356,723

G

calmodulin binding transcription activator 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAMTA2 mRNA

NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558

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calpain, small subunit 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAPNS1 mRNA

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

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cell cycle associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CAPRIN1 mRNA

NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502

G

caspase recruitment domain family, member 14

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CARD14 mRNA

NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905

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carnosine N-methyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CARNMT1 mRNA

NCBI chr 1:216,093,720...216,123,360
Ensembl chr 1:216,093,695...216,121,006

G

caspase 3

affects activity

2,3',4,4',5-pentachlorobiphenyl affects the activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

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caspase 7

affects activity

2,3',4,4',5-pentachlorobiphenyl affects the activity of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

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caspase 9

increases activity

2,3',4,4',5-pentachlorobiphenyl results in increased activity of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

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cation channel sperm associated auxiliary subunit gamma

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CATSPERG1 mRNA

NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559

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chromobox 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CBX5 mRNA

NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022

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chibby 1, beta catenin antagonist

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CBY1 mRNA

NCBI chr 7:111,216,835...111,223,305

G

coiled-coil and C2 domain containing 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CC2D2B mRNA

NCBI chr 1:239,561,506...239,655,771
Ensembl chr 1:239,561,987...239,682,416

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coiled-coil domain containing 112

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC112 mRNA

NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329

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coiled-coil domain containing 115

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC115 mRNA

NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946

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coiled-coil domain containing 117

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC117 mRNA

NCBI chr14:80,399,236...80,409,824
Ensembl chr14:80,400,294...80,409,659

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coiled-coil domain containing 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC12 mRNA

NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417

G

coiled-coil domain containing 124

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC124 mRNA

NCBI chr16:18,566,745...18,572,564
Ensembl chr16:18,566,745...18,572,564

G

coiled-coil domain containing 138

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC138 mRNA

NCBI chr20:26,493,624...26,572,367
Ensembl chr20:26,495,235...26,572,376

G

coiled-coil domain containing 162

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC162 mRNA

NCBI chr20:45,044,891...45,237,905
Ensembl chr20:45,032,752...45,236,193

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coiled-coil domain containing 178

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC178 mRNA

NCBI chr18:13,074,834...13,472,732
Ensembl chr18:13,075,468...13,472,160

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coiled-coil domain containing 187

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC187 mRNA

NCBI chr 3:9,070,192...9,127,001
Ensembl chr 3:9,070,185...9,126,946

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coiled-coil domain containing 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC6 mRNA

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

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coiled-coil domain containing 65

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC65 mRNA

NCBI chr 7:129,857,118...129,870,803
Ensembl chr 7:129,857,247...129,870,803

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coiled-coil domain containing 73

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC73 mRNA

NCBI chr 3:91,282,919...91,424,269
Ensembl chr 3:91,282,940...91,424,551

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coiled-coil domain containing 77

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCDC77 mRNA

NCBI chr 4:153,534,184...153,566,059
Ensembl chr 4:153,534,187...153,566,545

G

coiled-coil domain containing 85C

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CCDC85C mRNA

NCBI chr 6:127,113,440...127,184,328
Ensembl chr 6:127,113,442...127,184,371

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coiled-coil domain containing 88C

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CCDC88C mRNA

NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555

G

coiled-coil domain containing 92

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CCDC92 mRNA

NCBI chr12:31,796,102...31,823,333
Ensembl chr12:31,796,684...31,823,337

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C-C motif chemokine ligand 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

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cyclin A2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCNC mRNA

NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584

G

cyclin K

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCNK mRNA

NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191

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cyclin O

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCNO mRNA

NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914

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C-C motif chemokine receptor 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCR4 mRNA

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

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C-C motif chemokine receptor 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCR8 mRNA

NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629

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copper chaperone for superoxide dismutase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCS mRNA

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

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CCZ1 homolog, vacuolar protein trafficking and biogenesis associated

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CCZ1 mRNA

NCBI chr12:10,601,066...10,624,608
Ensembl chr12:10,601,056...10,624,608

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CD164 molecule

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CD164 mRNA

NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634

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CD164 molecule like 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CD164L2 mRNA

NCBI chr 5:145,414,805...145,427,747
Ensembl chr 5:145,423,892...145,427,720

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Cd7 molecule

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CD7 mRNA

NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967

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cytidine deaminase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDA mRNA

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

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cell division cycle 25A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDC25A mRNA

NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701

G

CDC42 effector protein 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDC42EP5 mRNA

NCBI chr 1:70,035,921...70,038,990

G

cell division cycle 45

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDC45 mRNA

NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619

G

cell division cycle 5-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDC5L mRNA

NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450

G

cadherin 18

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CDH18 mRNA

NCBI chr 2:72,818,076...73,820,144
Ensembl chr 2:73,345,005...73,820,138

G

cyclin-dependent kinase 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDK12 mRNA

NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888

G

cyclin-dependent kinase 13

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDK13 mRNA

NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721

G

cyclin-dependent kinase 20

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDK20 mRNA

NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826

G

cyclin-dependent kinase 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDK5 mRNA

NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112

G

CDK5 regulatory subunit associated protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDK5RAP2 mRNA

NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782

G

CDP-diacylglycerol synthase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDS1 mRNA

NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681

G

CDP-diacylglycerol synthase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CDS2 mRNA

NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541

G

CECR2, histone acetyl-lysine reader

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CECR2 mRNA

NCBI chr 4:153,890,310...153,998,078
Ensembl chr 4:153,890,206...153,993,451

G

centrosomal protein 112

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CEP112 mRNA

NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131

G

centrosomal protein 20

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CEP20 mRNA

NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837

G

centrosomal protein 76

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CEP76 mRNA

NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504

G

centrosomal protein 78

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CEP78 mRNA

NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181

G

centrosomal protein 85

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CEP85 mRNA

NCBI chr 5:146,356,571...146,404,155
Ensembl chr 5:146,356,576...146,404,060

G

cilia and flagella associated protein 206

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFAP206 mRNA

NCBI chr 5:49,254,399...49,299,145
Ensembl chr 5:49,254,408...49,299,090

G

cilia and flagella associated protein 251

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFAP251 mRNA

NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932

G

cilia and flagella associated protein 43

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFAP43 mRNA

NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443

G

cilia and flagella associated protein 61

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFAP61 mRNA

NCBI chr 3:133,354,400...133,633,310
Ensembl chr 3:133,354,197...133,633,320

G

cofilin 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

cofilin 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFL2 mRNA

NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674

G

complement factor properdin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CFP mRNA

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

charged multivesicular body protein 4C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CHMP4C mRNA

NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668

G

charged multivesicular body protein 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CHMP5 mRNA

NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529

G

chimerin 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CHN1 mRNA

NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490

G

cholinergic receptor, muscarinic 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CHRM1 mRNA

NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356

G

cholinergic receptor, muscarinic 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CHRM2 mRNA

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

carbohydrate sulfotransferase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CHST3 mRNA

NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

creatine kinase B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

CDC28 protein kinase regulatory subunit 1B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

cytoplasmic linker associated protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CLASP2 mRNA

NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731

G

chloride voltage-gated channel 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CLCN5 mRNA

NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264

G

claudin 5

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CLDN5 protein

NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992

G

claudin 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CLDN8 mRNA

NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513

G

C-type lectin domain family 2, member L

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CLEC2L mRNA

NCBI chr 4:67,392,118...67,414,539
Ensembl chr 4:67,397,873...67,414,537

G

CLN8, transmembrane ER and ERGIC protein

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of CLN8 mRNA

NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774

G

chemerin chemokine-like receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CMKLR2 mRNA

NCBI chr 9:64,583,310...64,617,883
Ensembl chr 9:64,585,594...64,586,655

G

cytidine/uridine monophosphate kinase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CMPK1 mRNA

NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830

G

CCR4-NOT transcription complex, subunit 6-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CNOT6L mRNA

NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203

G

canopy FGF signaling regulator 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CNPY4 mRNA

NCBI chr12:17,064,642...17,070,755
Ensembl chr12:17,064,642...17,070,043

G

cannabinoid receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CNR2 mRNA

NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548

G

contactin associated protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CNTNAP2 mRNA

NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027

G

cytochrome c oxidase assembly factor 7

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COA7 mRNA

NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199

G

component of oligomeric golgi complex 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COG4 mRNA

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

component of oligomeric golgi complex 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COG5 mRNA

NCBI chr 6:48,242,470...48,545,185
Ensembl chr 6:48,242,482...48,529,009

G

collagen type V alpha 2 chain

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

COMM domain containing 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COMMD9 mRNA

NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439

G

COP9 signalosome subunit 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COPS8 mRNA

NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258

G

COP9 signalosome subunit 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COPS9 mRNA

NCBI chr 9:93,209,843...93,214,774
Ensembl chr 9:93,209,843...93,213,317

G

COPI coat complex subunit zeta 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COPZ1 mRNA

NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662

G

coenzyme Q10B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COQ10B mRNA

NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663

G

coenzyme Q8B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COQ8B mRNA

NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180

G

cytochrome c oxidase copper chaperone COX17

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of COX17 mRNA

NCBI chr11:62,400,733...62,406,507

G

cytochrome c oxidase subunit 6A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COX6A1 mRNA

NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041

G

cytochrome c oxidase subunit 7A2 like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COX7A2L mRNA

NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273

G

cytochrome c oxidase subunit 7B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COX7B mRNA

NCBI chr X:71,083,486...71,089,733
Ensembl chr X:71,083,456...71,089,732

G

cytoplasmic polyadenylation element binding protein 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CPEB3 mRNA

NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560

G

copine 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CPNE5 mRNA

NCBI chr20:7,206,742...7,289,309
Ensembl chr20:7,206,742...7,288,883

G

carboxypeptidase Q

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CPQ mRNA

NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546

G

cleavage and polyadenylation specific factor 4

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of CPSF4 mRNA

NCBI chr12:9,429,765...9,445,586
Ensembl chr12:9,429,523...9,445,586

G

cellular retinoic acid binding protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CRABP2 mRNA

NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379

G

cAMP responsive element binding protein 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CREB5 mRNA

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

cysteine-rich secretory protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CRISP4 mRNA

NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796

G

CRK like proto-oncogene, adaptor protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CRKL mRNA

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

G

cryptochrome circadian regulator 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin beta-gamma domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CRYBG3 mRNA

NCBI chr11:40,749,198...40,861,753
Ensembl chr11:40,749,214...40,861,752

G

colony stimulating factor 3 receptor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CSF3R mRNA

NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881

G

cystatin A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CSTA2 mRNA

NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488

G

catenin alpha 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CTNNA3 mRNA

NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978

G

catenin, beta-interacting protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CTNNBIP1 mRNA

NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939

G

cut-like homeobox 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CUX1 mRNA

NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866

G

cytochrome b561 family, member D2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYB561D2 mRNA

NCBI chr 8:108,213,201...108,215,778
Ensembl chr 8:108,213,205...108,215,759

G

cytochrome b-245 beta chain

multiple interactions
increases expression

2,3',4,4',5-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 2,3',4,4',5-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYBB mRNA]

PMID:20299304 PMID:31251971

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 11, subfamily b, polypeptide 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP11B2 mRNA

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions
increases activity
increases metabolic processing

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA
2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
2,3',4,4',5-pentachlorobiphenyl results in increased activity of CYP1A1 protein
2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A1 protein
2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1A1 protein
CYP1A1 protein results in increased metabolism of 2,3',4,4',5-pentachlorobiphenyl

PMID:10986007 PMID:16750337 PMID:17342196 PMID:18493746 PMID:21781905 More...

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases activity
multiple interactions
increases activity
increases expression
decreases response to substance

2,3',4,4',5-pentachlorobiphenyl results in decreased activity of CYP1A2 protein
2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]
2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
2,3',4,4',5-pentachlorobiphenyl results in increased activity of CYP1A2 protein
2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA
CYP1A2 results in decreased susceptibility to 2,3',4,4',5-pentachlorobiphenyl
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein

PMID:10986007 PMID:15659567 PMID:17342196 PMID:18493746 PMID:20961953 More...

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA

PMID:23674508 PMID:25654323 PMID:29738842

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily b, polypeptide 1

multiple interactions
increases metabolic processing

[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP2B1 protein
CYP2B1 protein results in increased metabolism of 2,3',4,4',5-pentachlorobiphenyl

PMID:17342196 PMID:27208082

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 3

affects response to substance
increases metabolic processing

CYP2B6 gene SNP affects the susceptibility to 2,3',4,4',5-pentachlorobiphenyl
CYP2B6 protein results in increased metabolism of 2,3',4,4',5-pentachlorobiphenyl

PMID:25839716 PMID:27208082

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 4, subfamily x, polypeptide 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP4X1 mRNA

NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779

G

death-associated protein kinase 2

increases expression
multiple interactions
affects expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DAPK2 mRNA; 2,3',4,4',5-pentachlorobiphenyl results in increased expression of DAPK2 protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of DAPK2 protein]; 2,3',4,4',5-pentachlorobiphenyl promotes the reaction [TUBB3 protein binds to DAPK2 protein]; DAPK2 protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of PIK3C3 protein]; DAPK2 protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of PRKD1 protein]; TUBB3 protein promotes the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of DAPK2 protein]
2,3',4,4',5-pentachlorobiphenyl affects the expression of DAPK2 protein

PMID:31020377 PMID:32895711

NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567

G

aspartyl-tRNA synthetase 2 (mitochondrial)

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DARS2 mRNA

NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934

G

dysbindin domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DBNDD1 mRNA

NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444

G

DDB1 and CUL4 associated factor 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCAF12 mRNA

NCBI chr 5:56,460,418...56,482,171
Ensembl chr 5:56,461,006...56,482,456

G

dephospho-CoA kinase domain containing

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCAKD mRNA

NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054

G

DCC netrin 1 receptor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCC mRNA

NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740

G

decapping mRNA 1A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCP1A mRNA

NCBI chr16:5,656,960...5,702,151
Ensembl chr16:5,656,773...5,702,140

G

decapping enzyme, scavenger

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCPS mRNA

NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389

G

dopachrome tautomerase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCT mRNA

NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836

G

dynactin subunit 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCTN4 mRNA

NCBI chr18:53,982,355...54,009,409
Ensembl chr18:53,982,358...54,009,399

G

dynactin subunit 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DCTN6 mRNA

NCBI chr16:58,077,595...58,096,604
Ensembl chr16:58,077,585...58,096,968

G

DET1 and DDB1 associated 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDA1 mRNA

NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937

G

DNA damage inducible 1 homolog 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDI2 mRNA

NCBI chr 5:153,989,591...154,035,342
Ensembl chr 5:153,995,589...154,035,283

G

DNA-damage inducible transcript 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

discoidin domain receptor tyrosine kinase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDR1 mRNA

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

G

DEAD-box helicase 19A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDX19A mRNA

NCBI chr19:38,942,497...38,962,853
Ensembl chr19:38,942,496...38,962,854

G

DEAD-box helicase 3, X-linked

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDX3X mRNA

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

G

DEAD-box helicase 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DDX5 mRNA

NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283

G

death effector domain-containing

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DEDD mRNA

NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332

G

DEF6 guanine nucleotide exchange factor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DEF6 mRNA

NCBI chr20:6,268,579...6,290,030
Ensembl chr20:6,268,601...6,289,961

G

defensin beta 17

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DEFB41 mRNA

NCBI chr 9:20,880,246...20,883,875

G

DENN domain containing 1B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DENND1B mRNA

NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601

G

DENN domain containing 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DENN domain containing 5B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DENND5B mRNA

NCBI chr 4:181,959,597...182,089,661
Ensembl chr 4:181,961,386...182,089,362

G

DENN domain containing 6A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DENND6A mRNA

NCBI chr16:1,837,019...1,885,420
Ensembl chr16:1,837,059...1,885,420

G

DEP domain containing 5, GATOR1 subcomplex subunit

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DEPDC5 mRNA

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

deoxyribose-phosphate aldolase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DERA mRNA

NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865

G

derlin 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DERL2 mRNA

NCBI chr10:55,727,764...55,739,442
Ensembl chr10:55,727,643...55,739,518

G

derlin 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DERL3 mRNA

NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027

G

divergent protein kinase domain 2A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DIPK2A mRNA

NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815

G

DLG associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DLGAP1 mRNA

NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817

G

DLG associated protein 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DLGAP2 mRNA

NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407

G

distal membrane arm assembly component 1

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of DMAC1 mRNA

NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757

G

distal membrane arm assembly component 2 like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DMAC2L mRNA

NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933

G

DMRT-like family B with proline-rich C-terminal, 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DMRTB1 mRNA

NCBI chr 5:122,444,853...122,452,483
Ensembl chr 5:122,444,841...122,452,396

G

dynein, axonemal, assembly factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAAF1 mRNA

NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313

G

dynein, axonemal, heavy chain 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAH12 mRNA

NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664

G

dynein, axonemal, heavy chain 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DNAH2 mRNA

NCBI chr10:54,142,648...54,268,901
Ensembl chr10:54,142,737...54,267,298

G

dynein, axonemal, heavy chain 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAH8 mRNA

NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772

G

DnaJ heat shock protein family (Hsp40) member A4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAJA4 mRNA

NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207

G

DnaJ heat shock protein family (Hsp40) member B11

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAJB11 mRNA

NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407

G

DnaJ heat shock protein family (Hsp40) member B14

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DNAJB14 mRNA

NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490

G

DnaJ heat shock protein family (Hsp40) member C2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DNAJC2 mRNA

NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431

G

DNA methyltransferase 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DNMT1 mRNA

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DNMT3A mRNA

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 like

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DNMT3L mRNA

NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516

G

docking protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DOK2 mRNA

NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402

G

docking protein 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DOK6 mRNA

NCBI chr18:82,572,762...83,015,951
Ensembl chr18:82,572,762...83,015,951

G

dipeptidase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DPEP3 mRNA

NCBI chr19:33,868,229...33,876,609
Ensembl chr19:33,868,242...33,873,896

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of DPM3 mRNA

NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668

G

dipeptidylpeptidase 8

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DPP8 mRNA

NCBI chr 8:65,550,620...65,605,828
Ensembl chr 8:65,550,677...65,605,825

G

developmental pluripotency-associated 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DPPA2 mRNA

NCBI chr11:52,549,024...52,556,740

G

developmental pluripotency-associated 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DPPA3 mRNA

NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
Ensembl chr 5:155,815,296...155,854,861

G

dpy-19 like C-mannosyltransferase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DPY19L3 mRNA

NCBI chr 1:88,350,303...88,417,339
Ensembl chr 1:88,350,303...88,417,339

G

dpy-30 histone methyltransferase complex regulatory subunit

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DPY30 mRNA

NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432

G

dermatan sulfate epimerase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DSE mRNA

NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992

G

DSN1 component of MIS12 kinetochore complex

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DSN1 mRNA

NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856

G

dystonin

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DST mRNA

NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615

G

deltex E3 ubiquitin ligase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DTX2 mRNA

NCBI chr12:20,643,289...20,682,908
Ensembl chr12:20,643,297...20,682,885

G

deoxythymidylate kinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DTYMK mRNA

NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870

G

dual specificity phosphatase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DUSP1 mRNA

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 14

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DUSP14 mRNA

NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329

G

dual specificity phosphatase 16

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DUSP16 mRNA

NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980

G

dual specificity phosphatase 29

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DUSP29 mRNA

NCBI chr15:2,593,473...2,634,019
Ensembl chr15:2,593,578...2,633,503

G

dynein light chain LC8-type 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of DYNLL1 mRNA

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

G

E2F transcription factor 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of E2F4 mRNA

NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806

G

E2F-associated phosphoprotein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EAPP mRNA

NCBI chr 6:72,166,486...72,194,357
Ensembl chr 6:72,170,301...72,193,734

G

ecdysoneless cell cycle regulator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ECD mRNA

NCBI chr15:3,967,209...3,998,713
Ensembl chr15:3,967,382...3,998,706

G

endothelin-converting enzyme 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ECE2 mRNA

NCBI chr11:80,259,130...80,278,446
Ensembl chr11:80,263,162...80,278,428

G

Ecm29 proteasome adaptor and scaffold

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ECPAS mRNA

NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860

G

EGF like repeats and discoidin domains 3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of EDIL3 mRNA

NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008

G

EF-hand calcium binding domain 14

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EFCAB14 mRNA

NCBI chr 5:129,218,139...129,258,628
Ensembl chr 5:129,218,424...129,258,625

G

EF-hand domain family, member D1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of EFHD1 mRNA

NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917

G

EGF-like-domain, multiple 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

EH-domain containing 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EHD4 mRNA

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

G

EP300 interacting inhibitor of differentiation 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of EID2 mRNA

NCBI chr 1:83,538,274...83,539,599

G

eukaryotic translation initiation factor 2B subunit gamma

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EIF2B3 mRNA

NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332

G

eukaryotic translation initiation factor 4A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

eukaryotic translation initiation factor 4E nuclear import factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EIF4ENIF1 mRNA

NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793

G

eukaryotic translation initiation factor 5A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EIF5A mRNA

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

E74 like ETS transcription factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ELF2 mRNA

NCBI chr 2:135,292,291...135,385,942
Ensembl chr 2:135,294,906...135,385,947

G

ETS transcription factor ELK4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ELK4 mRNA

NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035

G

ER membrane protein complex subunit 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EMC8 mRNA

NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EMG1 mRNA

NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540

G

EMAP like 5

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of EML5 mRNA

NCBI chr 6:118,046,655...118,175,831
Ensembl chr 6:118,046,655...118,175,831

G

ENAH, actin regulator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ENAH mRNA

NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955

G

ectonucleoside triphosphate diphosphohydrolase 7

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ENTPD7 mRNA

NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447

G

erythrocyte membrane protein band 4.1-like 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of EPB41L1 mRNA

NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721

G

EPH receptor A10

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EPHA10 mRNA

NCBI chr 5:137,139,588...137,175,637
Ensembl chr 5:137,140,735...137,174,157

G

Eph receptor B1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EPHB1 mRNA

NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839

G

EPH receptor B4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EPHB4 mRNA

NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314

G

epidermal growth factor receptor pathway substrate 15

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EPS15 mRNA

NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221

G

Era-like 12S mitochondrial rRNA chaperone 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ERAL1 mRNA

NCBI chr10:62,961,725...62,968,747
Ensembl chr10:62,961,730...62,968,994

G

erb-b2 receptor tyrosine kinase 4

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ERBB4 mRNA

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

glutamate-rich 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ERICH1 mRNA

NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128

G

endoplasmic reticulum metallopeptidase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

estrogen receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ESR2 mRNA

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

electron transfer flavoprotein dehydrogenase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ETFDH mRNA

NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745

G

ETS variant transcription factor 4

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

exonuclease 3'-5' domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EXD2 mRNA

NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442

G

EYA transcriptional coactivator and phosphatase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of EYA3 mRNA

NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518

G

coagulation factor XII

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of F12 mRNA

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

G

coagulation factor VIII

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of F8 mRNA

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

G

family with sequence similarity 110, member C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM110C mRNA

NCBI chr 6:47,638,466...47,644,723
Ensembl chr 6:47,638,276...47,644,634

G

family with sequence similarity 117, member B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM117B mRNA

NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483

G

family with sequence similarity 118, member A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM118A mRNA

NCBI chr 7:116,152,448...116,178,976
Ensembl chr 7:116,146,716...116,178,971

G

family with sequence similarity 149, member A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM149A mRNA

NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066

G

family with sequence similarity 168, member A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM168A mRNA

NCBI chr 1:155,057,352...155,203,439
Ensembl chr 1:155,057,352...155,201,220

G

family with sequence similarity 168, member B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM168B mRNA

NCBI chr 9:37,005,569...37,038,631
Ensembl chr 9:37,006,689...37,033,723

G

family with sequence similarity 199, X-linked

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM199X mRNA

NCBI chr X:100,384,230...100,419,935
Ensembl chr X:100,384,225...100,414,938

G

FAM3 metabolism regulating signaling molecule C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM3C mRNA

NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078

G

family with sequence similarity 76, member A

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of FAM76A mRNA

NCBI chr 5:145,107,491...145,135,734
Ensembl chr 5:145,107,491...145,135,574

G

family with sequence similarity 78, member A

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of FAM78A mRNA

NCBI chr 3:15,355,958...15,376,330
Ensembl chr 3:15,355,955...15,373,812

G

FA complementation group C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FANCC mRNA

NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376

G

fructose-bisphosphatase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FBP1 mRNA

NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071

G

fibrosin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FBRS mRNA

NCBI chr 1:182,090,741...182,104,026
Ensembl chr 1:182,089,844...182,103,828

G

F-box protein 33

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FBXO33 mRNA

NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669

G

F-box protein 36

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FBXO36 mRNA

NCBI chr 9:86,042,522...86,107,220
Ensembl chr 9:86,040,862...86,107,229

G

fasciculation and elongation protein zeta 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FEZ1 mRNA

NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683

G

Fibroblast growth factor receptor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FGFR1 mRNA

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibroblast growth factor receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

four and a half LIM domains 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

folliculogenesis specific bHLH transcription factor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FIGLA mRNA

NCBI chr 4:118,432,517...118,436,846
Ensembl chr 4:118,432,765...118,436,690

G

fidgetin-like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FIGNL1 mRNA

NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455

G

fission, mitochondrial 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FLT3-interacting zinc finger 1

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of FIZ1 mRNA

NCBI chr 1:68,822,741...68,835,723
Ensembl chr 1:68,829,130...68,835,723

G

filamin C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FLNC mRNA

NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844

G

formation of mitochondrial complex V assembly factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FMC1 mRNA

NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140

G

formin binding protein 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FNBP4 mRNA

NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079

G

folliculin interacting protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FNIP1 mRNA

NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824

G

folate receptor alpha

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FOLR1 mRNA

NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667

G

forkhead box N3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of FOXN3 mRNA

NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401

G

forkhead box O3

multiple interactions

2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of and affects the localization of FOXO3 protein; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of FOXO3 protein]

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

FRAS1 related extracellular matrix 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FREM2 mRNA

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

FERM domain containing 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FRMD5 mRNA

NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498

G

follicle stimulating hormone subunit beta

multiple interactions

[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased expression of FSHB mRNA

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

ferritin domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FTDC2 mRNA

NCBI chr11:41,967,947...41,973,373
Ensembl chr11:41,968,796...41,972,351

G

ferritin light chain 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FTL1 mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

FtsJ RNA 2'-O-methyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FTSJ1 mRNA

NCBI chr X:14,243,684...14,256,555
Ensembl chr X:14,244,050...14,252,030

G

FXYD domain-containing ion transport regulator 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of FXYD4 mRNA

NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:151,109,779...151,113,637

G

G3BP stress granule assembly factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of G3BP1 mRNA

NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268

G

GA binding protein transcription factor subunit beta 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GABPB2 mRNA

NCBI chr 2:182,755,304...182,795,368
Ensembl chr 2:182,761,359...182,795,109

G

galactose-3-O-sulfotransferase 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GAL3ST2 mRNA

NCBI chr 9:94,382,456...94,387,990

G

galactose mutarotase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GALM mRNA

NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310

G

polypeptide N-acetylgalactosaminyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

Grb2-binding adaptor protein, transmembrane

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GAPT mRNA

NCBI chr 2:41,927,533...41,932,120
Ensembl chr 2:41,927,532...41,932,093

G

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GART mRNA

NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125

G

GATA zinc finger domain containing 2A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GATAD2A mRNA

NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587

G

glutamine amidotransferase class 1 domain containing 3A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GATD3A mRNA

NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885

G

golgi brefeldin A resistant guanine nucleotide exchange factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GBF1 mRNA

NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042

G

ganglioside-induced differentiation-associated-protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GDAP2 mRNA

NCBI chr 2:187,528,514...187,585,270
Ensembl chr 2:187,528,513...187,585,270

G

growth differentiation factor 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GDF9 mRNA

NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672

G

glycerophosphodiester phosphodiesterase domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GDPD3 mRNA

NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GDPD5 mRNA

NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446

G

gem (nuclear organelle) associated protein 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GEMIN6 mRNA

NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612

G

GID complex subunit 8 homolog

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GID8 mRNA

NCBI chr 3:167,826,006...167,836,759
Ensembl chr 3:167,826,060...167,834,814

G

GRB10 interacting GYF protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GIGYF2 mRNA

NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715

G

GINS complex subunit 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GINS2 mRNA

NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339

G

gap junction protein, alpha 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GJA4 mRNA

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

galactosidase, alpha

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GLA mRNA

NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664

G

glucuronic acid epimerase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GLCE mRNA

NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040

G

GLI family zinc finger 2

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of GLI2 mRNA

NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574

G

glutaredoxin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

G protein subunit alpha 14

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GNA14 mRNA

NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423

G

G protein subunit alpha L

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GNAL mRNA

NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599

G

G protein subunit beta 1 like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GNB1L mRNA

NCBI chr11:82,425,301...82,507,836
Ensembl chr11:82,432,627...82,507,466

G

glucosamine-phosphate N-acetyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GNPNAT1 mRNA

NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739

G

gonadotropin releasing hormone 1

affects expression
multiple interactions

2,3',4,4',5-pentachlorobiphenyl affects the expression of GNRH1 protein
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 2,4,4',5-tetrachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] affects the expression of GNRH1 protein; fulvestrant affects the reaction [2,3',4,4',5-pentachlorobiphenyl affects the expression of GNRH1 protein]

NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581

G

GC-rich promoter binding protein 1-like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GPBP1L1 mRNA

NCBI chr 5:130,009,768...130,050,636
Ensembl chr 5:130,023,137...130,050,459

G

glypican 5

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of GPC5 mRNA

NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282

G

G protein-coupled receptor 137C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GPR137C mRNA

NCBI chr15:18,425,939...18,492,588
Ensembl chr15:18,426,223...18,490,807

G

GRAM domain containing 2B

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of GRAMD2B mRNA

NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953

G

GREB1 like retinoic acid receptor coactivator

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of GREB1L mRNA

NCBI chr18:1,392,330...1,629,483
Ensembl chr18:1,392,725...1,628,067

G

grainyhead-like transcription factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRHL1 mRNA

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

G

grainyhead-like transcription factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRHL2 mRNA

NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258

G

glutamate ionotropic receptor NMDA type subunit 2A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRIN2A mRNA

NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637

G

glutamate receptor interacting protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRIP1 mRNA

NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273

G

G protein-coupled receptor kinase 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRK4 mRNA

NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693

G

glutamate metabotropic receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GRM2 mRNA

NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146

G

glutathione S-transferase pi 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

general transcription factor 2A subunit 1 like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GTF2A1L mRNA

NCBI chr 6:5,752,814...5,834,797
Ensembl chr 6:5,752,823...5,836,472

G

general transcription factor III A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GTF3A mRNA

NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690

G

general transcription factor 3C subunit 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GTF3C6 mRNA

NCBI chr20:43,656,400...43,668,382
Ensembl chr20:43,655,875...43,667,873

G

guanylate cyclase activator 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GUCA2B mRNA

NCBI chr 5:133,246,891...133,248,941
Ensembl chr 5:133,246,909...133,248,966

G

glycogenin 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of GYG1 mRNA

NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797

G

H1.0 linker histone

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.8 linker histone

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H1F8 mRNA

NCBI chr 4:148,993,133...148,998,254
Ensembl chr 4:148,993,133...148,998,254

G

H2A.J histone

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2AJ mRNA

NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006

G

H2A.X variant histone

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2AX mRNA

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

H2B clustered histone 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2BC8 mRNA

NCBI chr17:42,708,658...42,709,408

G

H3.3 histone A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H3F3A mRNA

NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908

G

H3.3 histone B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H3F3B mRNA

NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709

G

3-hydroxyacyl-CoA dehydratase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

hydroxyacid oxidase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HAO1 mRNA

NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721

G

HAUS augmin-like complex, subunit 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HAUS4 mRNA

NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938

G

heparin binding growth factor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HDGF mRNA

NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747

G

HEAT repeat containing 5A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HEATR5A mRNA

NCBI chr 6:69,321,869...69,419,861
Ensembl chr 6:69,321,869...69,419,773

G

heart development protein with EGF-like domains 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HEG1 mRNA

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

G

helicase with zinc finger

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HELZ mRNA

NCBI chr10:92,479,403...92,645,234
Ensembl chr10:92,501,518...92,638,383

G

hemogen

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of HEMGN mRNA

NCBI chr 5:60,679,633...60,698,597
Ensembl chr 5:60,679,633...60,698,669

G

hes family bHLH transcription factor 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hexosaminidase D

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HEXD mRNA

NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799

G

heparan-alpha-glucosaminide N-acetyltransferase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of HGSNAT mRNA

NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138

G

hematopoietically expressed homeobox

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

HIG1 hypoxia inducible domain family, member 1C

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HIGD1C mRNA

NCBI chr 7:131,477,730...131,498,853
Ensembl chr 7:131,478,519...131,498,214

G

heat shock protein nuclear import factor hikeshi

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HIKESHI mRNA

NCBI chr 1:143,825,399...143,849,361
Ensembl chr 1:143,825,923...143,849,363

G

histone cluster 1 H2A family member H

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2AC11 mRNA

NCBI chr17:41,384,521...41,385,018

G

histone cluster 1, H2bc

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2BC4 mRNA

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

G

histone cluster 1 H4 family member B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H4C9 mRNA

NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370

G

histone cluster 1, H4m

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H4C1 mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

histone cluster 2 H2B family member E

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2BC11 mRNA

NCBI chr 2:183,780,583...183,783,030

G

helicase-like transcription factor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HLTF mRNA

NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327

G

hemicentin 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HMCN1 mRNA

NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524

G

high mobility group AT-hook 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HMGA1 mRNA

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

G

high mobility group box 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HMGB3 mRNA

NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292

G

heterogeneous nuclear ribonucleoprotein A0

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HNRNPA0 mRNA

NCBI chr17:6,507,728...6,510,385
Ensembl chr17:6,507,275...6,509,375

G

4-hydroxy-2-oxoglutarate aldolase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HOGA1 mRNA

NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568

G

hook microtubule-tethering protein 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HOOK3 mRNA

NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338

G

HORMA domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HORMAD1 mRNA

NCBI chr 2:183,115,815...183,152,383
Ensembl chr 2:183,116,716...183,152,383

G

HPS5, biogenesis of lysosomal organelles complex 2 subunit 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HPS5 mRNA

NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019

G

heparan sulfate 2-O-sulfotransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HS2ST1 mRNA

NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769

G

hydroxysteroid (17-beta) dehydrogenase 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HSD17B12 mRNA

NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617

G

hydroxysteroid (17-beta) dehydrogenase 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

heat shock protein family A (Hsp70) member 9

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of HSPA9 mRNA

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

HtrA serine peptidase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

hyccin PI4KA lipid kinase complex subunit 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of HYCC2 mRNA

NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007

G

isoleucyl-tRNA synthetase 2, mitochondrial

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of IARS2 mRNA

NCBI chr13:96,831,484...96,865,518
Ensembl chr13:96,831,484...96,865,501

G

intercellular adhesion molecule 1

increases expression
affects response to substance
multiple interactions

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA; 2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 protein
ICAM1 protein affects the susceptibility to 2,3',4,4',5-pentachlorobiphenyl
alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; MAPK9 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]

PMID:22240979 PMID:26519956

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

Idnk, gluconokinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IDNK mRNA

NCBI chr17:6,483,575...6,490,780
Ensembl chr17:6,483,576...6,490,905

G

alpha-L-iduronidase

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of IDUA mRNA

NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522

G

immediate early response 5-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IER5L mRNA

NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647

G

intraflagellar transport 74

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IFT74 mRNA

NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833

G

insulin-like growth factor 1 receptor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IGF1R mRNA

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 mRNA binding protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IGF2BP1 mRNA

NCBI chr10:80,908,300...80,951,097
Ensembl chr10:80,908,076...80,951,129

G

insulin-like growth factor 2 receptor

decreases methylation
increases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased methylation of IGF2R gene
2,3',4,4',5-pentachlorobiphenyl results in increased expression of IGF2R mRNA

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

interleukin 1 receptor accessory protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL1RAP mRNA

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

G

interleukin 1 receptor accessory protein-like 2

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of IL1RAPL2 mRNA

NCBI chr X:100,961,509...102,271,753
Ensembl chr X:100,961,812...102,271,753

G

interleukin 6

increases expression
multiple interactions

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA; 2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 protein
alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]; MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]; MAPK9 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inhibitor of CDK, cyclin A1 interacting protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of INCA1 mRNA

NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114

G

inositol polyphosphate-5-phosphatase A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of INPP5A mRNA

NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428

G

inositol polyphosphate-5-phosphatase F

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of INPP5F mRNA

NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276

G

insulin induced gene 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

inositol hexakisphosphate kinase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IP6K1 mRNA

NCBI chr 8:108,693,068...108,737,278

G

interaction protein for cytohesin exchange factors 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IPCEF1 mRNA

NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969

G

importin 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IPO8 mRNA

NCBI chr 4:181,729,216...181,793,672
Ensembl chr 4:181,729,220...181,793,161

G

inositol-pentakisphosphate 2-kinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IPPK mRNA

NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541

G

interferon regulatory factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IRF1 mRNA

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 3

multiple interactions

[2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides] results in increased phosphorylation of and affects the localization of IRF3 protein; IRF3 mutant form inhibits the reaction [[2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein]; IRF3 results in increased susceptibility to [2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides]

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

G

isochorismatase domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ISOC1 mRNA

NCBI chr18:52,158,790...52,179,206
Ensembl chr18:52,158,790...52,178,703

G

itchy E3 ubiquitin protein ligase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ITCH mRNA

NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543

G

integrin subunit alpha 11

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ITGA11 mRNA

NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407

G

integrin subunit beta 3 binding protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ITGB3BP mRNA

NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704

G

integrin subunit beta 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ITGB4 mRNA

NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012

G

integral membrane protein 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ITM2B mRNA

NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917

G

inositol 1,4,5-trisphosphate receptor, type 3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ITPR3 mRNA

NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337

G

IZUMO1 receptor, JUNO

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of IZUMO1R mRNA

NCBI chr 8:11,744,384...11,748,131
Ensembl chr 8:11,725,863...11,748,465

G

jagged canonical Notch ligand 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of JAG1 mRNA

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

Josephin domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of JOSD2 mRNA

NCBI chr 1:94,960,867...94,964,751
Ensembl chr 1:94,961,107...94,964,749

G

KAT8 regulatory NSL complex subunit 1-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KANSL1L mRNA

NCBI chr 9:68,211,151...68,316,992
Ensembl chr 9:68,211,189...68,300,222

G

lysine acetyltransferase 6A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KAT6A mRNA

NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606

G

katanin catalytic subunit A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KATNA1 mRNA

NCBI chr 1:2,202,501...2,244,132
Ensembl chr 1:2,202,490...2,244,131

G

potassium channel modulatory factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCMF1 mRNA

NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234

G

potassium voltage-gated channel subfamily A regulatory beta subunit 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNAB1 mRNA

NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534

G

potassium voltage-gated channel modifier subfamily G member 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNG2 mRNA

NCBI chr18:73,742,224...73,810,420
Ensembl chr18:73,743,074...73,808,723

G

potassium voltage-gated channel modifier subfamily G member 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNG3 mRNA

NCBI chr 6:11,051,311...11,099,264
Ensembl chr 6:11,051,134...11,099,264

G

potassium voltage-gated channel interacting protein 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNIP4 mRNA

NCBI chr14:61,380,699...62,531,399
Ensembl chr14:61,381,076...62,530,144

G

potassium calcium-activated channel subfamily M regulatory beta subunit 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KCNMB2 mRNA

NCBI chr 2:114,670,027...114,975,374
Ensembl chr 2:114,935,976...114,975,173

G

potassium calcium-activated channel subfamily U member 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNU1 mRNA

NCBI chr16:66,141,696...66,229,493
Ensembl chr16:66,141,976...66,229,465

G

potassium channel tetramerization domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCTD3 mRNA

NCBI chr13:100,510,193...100,548,765
Ensembl chr13:100,510,195...100,548,718

G

KDEL endoplasmic reticulum protein retention receptor 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KDELR2 mRNA

NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153

G

lysine demethylase 3A

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of KDM3A mRNA

NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073

G

lysine demethylase 4C

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KDM4C mRNA

NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818

G

lysine demethylase 6B

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KDM6B mRNA

NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794

G

ketohexokinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KHK mRNA

NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717

G

KH-type splicing regulatory protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KHSRP mRNA

NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451

G

kinase D-interacting substrate 220

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KIDINS220 mRNA

NCBI chr 6:41,618,207...41,706,990
Ensembl chr 6:41,618,294...41,703,256

G

kinesin family member 3a

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KIF3A mRNA

NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191

G

kinesin family member 4A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KIF4 mRNA

NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139

G

kelch domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KLHDC3 mRNA

NCBI chr 9:14,302,345...14,308,736
Ensembl chr 9:14,302,354...14,308,736

G

kelch domain containing 8B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KLHDC8B mRNA

NCBI chr 8:109,141,594...109,146,584
Ensembl chr 8:109,141,594...109,146,918

G

kelch-like family member 7

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KLHL7 mRNA

NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541

G

lysine methyltransferase 5A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KMT5A mRNA

NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711

G

karyopherin subunit alpha 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KPNA1 mRNA

NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623

G

lysine-rich coiled-coil 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KRCC1 mRNA

NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156

G

keratin 88

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KRT88 mRNA

NCBI chr 7:132,566,087...132,571,946
Ensembl chr 7:132,561,724...132,571,944

G

KxDL motif containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KXD1 mRNA

NCBI chr16:18,895,343...18,916,266
Ensembl chr16:18,900,616...18,920,807

G

kyphoscoliosis peptidase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of KY mRNA

NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024

G

L3MBTL histone methyl-lysine binding protein 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of L3MBTL4 mRNA

NCBI chr 9:108,295,004...108,747,879
Ensembl chr 9:108,329,669...108,747,774

G

laminin subunit alpha 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

lysosomal-associated membrane protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LAMP1 mRNA

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LAMTOR1 mRNA

NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LAMTOR3 mRNA

NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LAMTOR4 mRNA

NCBI chr12:17,258,656...17,262,478
Ensembl chr12:17,258,623...17,262,480

G

La ribonucleoprotein 1, translational regulator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LARP1 mRNA

NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371

G

large tumor suppressor kinase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LATS2 mRNA

NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220

G

lamin B receptor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LBR mRNA

NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017

G

lactate dehydrogenase A

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; PKM protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]

PMID:30821169 PMID:31251971

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

lactate dehydrogenase B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHB mRNA

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

luteinizing hormone subunit beta

multiple interactions

[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased expression of LHB mRNA

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM homeobox 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LHX2 mRNA

NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908

G

LIM homeobox 8

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LHX8 mRNA

NCBI chr 2:243,244,958...243,269,624
Ensembl chr 2:243,244,961...243,269,416

G

LIM domain containing 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of LIMD1 mRNA

NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:123,122,460...123,167,714

G

LIM zinc finger domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LIMS1 mRNA

NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500

G

lin-28 homolog B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LIN28B mRNA

NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077

G

lin-37 DREAM MuvB core complex component

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LIN37 mRNA

NCBI chr 1:85,809,065...85,813,235
Ensembl chr 1:85,809,074...85,812,991

G

lin-52 DREAM MuvB core complex component

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LIN52 mRNA

NCBI chr 6:104,098,818...104,199,323
Ensembl chr 6:104,099,162...104,194,103

G

lipase H

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LIPH mRNA

NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625

G

lamin tail domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LMNTD1 mRNA

NCBI chr 4:178,354,302...178,588,483
Ensembl chr 4:178,354,137...178,588,477

G

LIM domain 7

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LMO7 mRNA

NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783

G

lysophosphatidylcholine acyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LPCAT1 mRNA

NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401

G

lysophosphatidylcholine acyltransferase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LPCAT3 mRNA

NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880

G

LRAT domain containing 1

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of LRATD1 mRNA

NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319

G

LDL receptor related protein associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LRPAP1 mRNA

NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414

G

leucine rich repeat containing 20

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of LRRC20 mRNA

NCBI chr20:29,422,858...29,528,372
Ensembl chr20:29,422,925...29,528,369

G

leucine rich repeat containing 42

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LRRC42 mRNA

NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829

G

leucine rich repeat containing 57

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LRRC57 mRNA

NCBI chr 3:107,544,786...107,553,256
Ensembl chr 3:107,547,405...107,553,256

G

leucine rich repeat containing 8 VRAC subunit E

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LRRC8E mRNA

NCBI chr12:2,578,240...2,589,407
Ensembl chr12:2,578,315...2,589,412

G

LSM10, U7 small nuclear RNA associated

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of LSM10 mRNA

NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505

G

LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LSM7 mRNA

NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119

G

latent transforming growth factor beta binding protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LTBP1 mRNA

NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349

G

LUC7-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LUC7L mRNA

NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112

G

lysozyme G2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LYG2 mRNA

NCBI chr 9:40,141,144...40,150,821
Ensembl chr 9:40,141,381...40,150,821

G

LYN proto-oncogene, Src family tyrosine kinase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of LYN mRNA

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

G

lysosomal enzyme trafficking factor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of LYSET mRNA

NCBI chr 6:121,884,577...121,886,319
Ensembl chr 6:121,884,643...121,886,275

G

mannosidase beta

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MANBA mRNA

NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983

G

microtubule-associated protein 1 light chain 3 alpha

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MAP1LC3A mRNA

NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670

G

mitogen activated protein kinase kinase kinase 3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MAP3K3 mRNA

NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848

G

mitogen-activated protein kinase kinase kinase kinase 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MAP4K3 mRNA

NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334

G

MAP7 domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MAP7D2 mRNA

NCBI chr X:35,372,453...35,488,073
Ensembl chr X:35,372,700...35,488,091

G

mitogen activated protein kinase 1

decreases phosphorylation

2,3',4,4',5-pentachlorobiphenyl results in decreased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 1 interacting protein 1-like

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of MAPK1IP1L mRNA

NCBI chr15:20,545,043...20,571,466
Ensembl chr15:20,545,059...20,569,674

G

mitogen activated protein kinase 3

decreases phosphorylation

2,3',4,4',5-pentachlorobiphenyl results in decreased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
increases expression
increases phosphorylation

MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]
2,3',4,4',5-pentachlorobiphenyl results in increased expression of MAPK8 mRNA
2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein

PMID:26519956 PMID:31388691 PMID:36450500

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions

MAPK9 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; MAPK9 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

MAS1 proto-oncogene, G protein-coupled receptor

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MAS1 mRNA

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

G

methyl-CpG binding domain protein 3-like 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MBD3L2 mRNA

NCBI chr 8:15,607,477...15,614,046
Ensembl chr 8:15,611,214...15,612,563

G

multiciliate differentiation and DNA synthesis associated cell cycle protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MCIDAS mRNA

NCBI chr 2:44,636,820...44,644,551
Ensembl chr 2:44,636,856...44,642,601

G

minichromosome maintenance complex component 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MCM4 mRNA

NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144

G

minichromosome maintenance complex component 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MCM5 mRNA

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

minichromosome maintenance complex binding protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MCMBP mRNA

NCBI chr 1:183,270,598...183,316,975
Ensembl chr 1:183,271,980...183,316,975

G

microspherule protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MCRS1 mRNA

NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685

G

malate dehydrogenase 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MDH2 mRNA

NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271

G

midasin AAA ATPase 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MDN1 mRNA

NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332

G

mediator complex subunit 15

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED15 mRNA

NCBI chr11:83,280,722...83,356,006
Ensembl chr11:83,280,762...83,355,362

G

mediator complex subunit 19

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED19 mRNA

NCBI chr 3:69,762,138...69,772,661
Ensembl chr 3:69,762,166...69,772,036

G

mediator complex subunit 21

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED21 mRNA

NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548

G

mediator complex subunit 26

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of MED26 mRNA

NCBI chr16:17,299,722...17,350,168
Ensembl chr16:17,299,722...17,349,543

G

mediator complex subunit 27

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED27 mRNA

NCBI chr 3:12,629,593...12,803,340
Ensembl chr 3:12,629,603...12,803,339

G

mediator complex subunit 30

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED30 mRNA

NCBI chr 7:84,004,735...84,026,474
Ensembl chr 7:84,004,722...84,026,595

G

mediator complex subunit 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MED9 mRNA

NCBI chr10:44,750,667...44,765,464
Ensembl chr10:44,750,698...44,765,464

G

Meis homeobox 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MEIS2 mRNA

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

mesoderm posterior bHLH transcription factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MESP2 mRNA

NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198

G

methyltransferase 5, N6-adenosine

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of METTL5 mRNA

NCBI chr 3:54,625,790...54,638,066
Ensembl chr 3:54,625,793...54,638,039

G

microfibril associated protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MFAP2 mRNA

NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MGAT4A mRNA

NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890

G

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MGAT5 mRNA

NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513

G

mitochondrial contact site and cristae organizing system subunit 13

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MICOS13 mRNA

NCBI chr 9:1,439,841...1,441,782
Ensembl chr 9:1,439,058...1,442,076

G

MIER1 transcriptional regulator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MIER1 mRNA

NCBI chr 5:117,876,012...117,927,592
Ensembl chr 5:117,870,382...117,927,589

G

makorin, ring finger protein, 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MKRN2 mRNA

NCBI chr 4:148,661,529...148,679,580
Ensembl chr 4:148,661,553...148,679,642

G

myeloid leukemia factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MLF2 mRNA

NCBI chr 4:157,739,651...157,744,325
Ensembl chr 4:157,728,756...157,744,317

G

MLLT10, histone lysine methyltransferase DOT1L cofactor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MLLT10 mRNA

NCBI chr17:80,821,870...80,949,349
Ensembl chr17:80,822,556...80,949,345

G

MORN repeat containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MORN1 mRNA

NCBI chr 5:165,646,817...165,704,892
Ensembl chr 5:165,646,991...165,704,892

G

MOS proto-oncogene, serine/threonine kinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MOS mRNA

NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264

G

MPL proto-oncogene, thrombopoietin receptor

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MPL mRNA

NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797

G

MAGUK p55 scaffold protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MPP1 mRNA

G

metallophosphoesterase domain containing 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MPPED2 mRNA

NCBI chr 3:93,180,895...93,355,605
Ensembl chr 3:93,181,167...93,355,618

G

MRN complex interacting protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRNIP mRNA

NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469

G

mitochondrial ribosomal protein L27

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MRPL27 mRNA

NCBI chr10:79,595,459...79,601,242
Ensembl chr10:79,595,479...79,601,239

G

mitochondrial ribosomal protein L36

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of MRPL36 mRNA

NCBI chr 1:29,965,481...29,968,896
Ensembl chr 1:29,965,317...29,968,807

G

mitochondrial ribosomal protein L45

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPL45 mRNA

NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474

G

mitochondrial ribosomal protein L46

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPL46 mRNA

NCBI chr 1:132,698,872...132,707,639
Ensembl chr 1:132,698,601...132,707,628

G

mitochondrial ribosomal protein L53

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPL53 mRNA

NCBI chr 4:115,615,329...115,616,219

G

mitochondrial ribosomal protein L57

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPL57 mRNA

NCBI chr15:31,970,904...31,971,766
Ensembl chr15:31,970,860...31,973,993

G

mitochondrial ribosomal protein S18B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPS18B mRNA

NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260

G

mitochondrial ribosomal protein S25

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MRPS25 mRNA

NCBI chr 4:124,668,320...124,680,086
Ensembl chr 4:124,668,094...124,680,057

G

membrane spanning 4-domains A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MS4A1 mRNA

NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512

G

Myb/SANT DNA binding domain containing 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MSANTD3 mRNA

NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859

G

mutS homolog 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MSH5 mRNA

NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336

G

mitochondrially encoded cytochrome c oxidase I

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

metastasis associated 1 family, member 3

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MTA3 mRNA

NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883

G

mitochondrial fission regulator 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MTFR1 mRNA

NCBI chr 2:101,678,331...101,713,547
Ensembl chr 2:101,679,265...101,713,544

G

myotrophin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MTPN mRNA

NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724

G

MTSS I-BAR domain containing 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MTSS1 mRNA

NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968

G

microtubule associated scaffold protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MTUS2 mRNA

NCBI chr12:6,706,531...7,078,331
Ensembl chr12:6,706,532...7,078,331

G

mucin 13, cell surface associated

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MUC13 mRNA

NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727

G

mitochondrial E3 ubiquitin protein ligase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MUL1 mRNA

NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863

G

major vault protein

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MVP mRNA

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

G

myelin expression factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MYEF2 mRNA

NCBI chr 3:112,338,241...112,374,122
Ensembl chr 3:112,338,241...112,374,181

G

myosin, heavy chain 15

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MYH15 mRNA

NCBI chr11:51,621,924...51,763,037
Ensembl chr11:51,622,413...51,762,971

G

myosin, heavy chain 9

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MYH9 mRNA

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

G

myosin, light chain 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MYL4 mRNA

NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363

G

myogenin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MYOG mRNA

NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039

G

myocardial zonula adherens protein

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of MYZAP mRNA

NCBI chr 8:72,155,817...72,243,036
Ensembl chr 8:72,131,530...72,243,036

G

mitotic spindle organizing protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MZT1 mRNA

NCBI chr15:75,787,281...75,797,589
Ensembl chr15:75,786,994...75,797,589

G

mitotic spindle organizing protein 2B

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of MZT2 mRNA

NCBI chr11:85,024,120...85,031,960
Ensembl chr11:85,024,315...85,031,167

G

NEDD4 binding protein 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of N4BP2 mRNA

NCBI chr14:42,342,690...42,479,861
Ensembl chr14:42,409,510...42,483,960

G

N-acetylated alpha-linked acidic dipeptidase-like 2

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NAALADL2 mRNA

NCBI chr 2:106,639,146...107,992,218
Ensembl chr 2:106,645,608...107,991,689

G

sodium leak channel, non-selective

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NALCN mRNA

NCBI chr15:100,398,583...100,741,243
Ensembl chr15:100,398,615...100,741,001

G

NALCN channel auxiliary factor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NALF1 mRNA

NCBI chr16:79,713,577...80,236,295
Ensembl chr16:79,713,724...80,235,120

G

nucleosome assembly protein 1-like 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NAP1L4 mRNA

NCBI chr 1:198,709,697...198,746,093
Ensembl chr 1:198,709,701...198,746,020

G

NAD(P)HX epimerase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NAXE mRNA

NCBI chr 2:173,518,971...173,521,036
Ensembl chr 2:173,518,971...173,521,040

G

neutrophil cytosolic factor 1

multiple interactions
increases localization
increases phosphorylation
increases expression

2,3',4,4',5-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 2,3',4,4',5-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]; acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF1 mRNA]
2,3',4,4',5-pentachlorobiphenyl results in increased localization of NCF1 protein

PMID:20299304 PMID:30821169 PMID:31251971

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

neutrophil cytosolic factor 4

multiple interactions
increases expression

AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF4 mRNA]

PMID:30821169 PMID:31251971

NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389

G

NCK-associated protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCKAP1 mRNA

NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217

G

nuclear receptor coactivator 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCOA4 mRNA

NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641

G

nuclear receptor co-repressor 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCOR1 mRNA

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

nudE neurodevelopment protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDE1 mRNA

NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869

G

nudE neurodevelopment protein 1-like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDEL1 mRNA

NCBI chr10:53,505,628...53,582,025
Ensembl chr10:53,516,491...53,570,907

G

NADH:ubiquinone oxidoreductase subunit A1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDUFA1 mRNA

NCBI chr X:116,424,223...116,427,875
Ensembl chr X:116,424,223...116,428,633

G

NADH:ubiquinone oxidoreductase subunit A2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDUFA2 mRNA

NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076

G

NADH:ubiquinone oxidoreductase complex assembly factor 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDUFAF4 mRNA

NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336

G

NADH:ubiquinone oxidoreductase subunit B3

increases expression
decreases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NDUFB3 mRNA
2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NDUFB3 mRNA

PMID:31388691 PMID:36450500

NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446

G

nuclear factor of activated T-cells 3

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of NFATC3 mRNA

NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150

G

NFE2 like bZIP transcription factor 3

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NFE2L3 mRNA

NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629

G

NFKB inhibitor beta

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NFKBIB mRNA

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

NHERF family PDZ scaffold protein 2

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of NHERF2 mRNA

NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049

G

NHS-like 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NHSL2 mRNA

NCBI chr X:66,969,953...67,209,464
Ensembl chr X:66,970,151...67,200,911

G

ninjurin 1

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NINJ1 mRNA

NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704

G

nipsnap homolog 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NIPSNAP2 mRNA

NCBI chr12:26,906,068...26,944,201
Ensembl chr12:26,911,723...26,944,166

G

nemo like kinase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NLK mRNA

NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730

G

NLR family, pyrin domain containing 12

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NLRP12 mRNA

NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934

G

NME/NM23 nucleoside diphosphate kinase 6

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NME6 mRNA

NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301

G

N-myristoyltransferase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NMT1 mRNA

NCBI chr10:87,988,826...88,025,405
Ensembl chr10:87,988,826...88,022,648

G

nocturnin

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

non-POU domain containing, octamer-binding

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NONO mRNA

NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952

G

notochord homeobox

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NOTO mRNA

NCBI chr 4:117,961,163...117,965,402
Ensembl chr 4:117,961,163...117,965,402

G

aminopeptidase puromycin sensitive

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NPEPPS mRNA

NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967

G

neuropeptide FF receptor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NPFFR2 mRNA

NCBI chr14:18,513,120...18,558,074
Ensembl chr14:18,513,277...18,521,919

G

NPHS1 adhesion molecule, nephrin

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NPHS1 mRNA

NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078

G

NPR2-like, GATOR1 complex subunit

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NPRL2 mRNA

NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

2,3',4,4',5-pentachlorobiphenyl binds to and results in increased activity of NR1I2 protein
2,3',4,4',5-pentachlorobiphenyl results in increased activity of NR1I2 protein

PMID:15885729 PMID:16054614 PMID:25680588

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 2, group E, member 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NR2E1 mRNA

NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949

G

nuclear receptor subfamily 3, group C, member 1

increases activity
multiple interactions

2,3',4,4',5-pentachlorobiphenyl results in increased activity of NR3C1 protein
2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor binding factor 2

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NRBF2 mRNA

NCBI chr20:21,308,555...21,326,881
Ensembl chr20:21,308,576...21,326,818

G

nuclear receptor binding SET domain protein 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NSD1 mRNA

NCBI chr17:9,311,963...9,426,373
Ensembl chr17:9,315,237...9,425,358

G

NAD(P) dependent steroid dehydrogenase-like

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NSDHL mRNA

NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142

G

NOP2/Sun RNA methyltransferase 3

affects expression

2,3',4,4',5-pentachlorobiphenyl affects the expression of NSUN3 mRNA

NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543

G

netrin 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NTN4 mRNA

NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390

G

nudix hydrolase 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NUDT1 mRNA

NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826

G

nudix hydrolase 13

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NUDT13 mRNA

NCBI chr15:4,001,787...4,022,404
Ensembl chr15:4,001,794...4,022,293

G

nudix hydrolase 16 like 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NUDT16L1 mRNA

NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370

G

nudix hydrolase 4

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NUDT4 mRNA

NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615

G

nucleoporin 210-like

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NUP210L mRNA

NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332

G

nucleoporin 98 and 96 precursor

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NUP98 mRNA

NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415

G

nuclear protein 2, transcriptional regulator

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NUPR2 mRNA

NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304

G

nucleoredoxin

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of NXN mRNA

NCBI chr10:61,109,322...61,247,578
Ensembl chr10:61,110,020...61,248,251

G

occludin

multiple interactions
decreases expression

[2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein]; IRF3 mutant form inhibits the reaction [[2,3',4,4',5-pentachlorobiphenyl co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein]
2,3',4,4',5-pentachlorobiphenyl results in decreased expression of OCLN protein
2,3',4,4',5-pentachlorobiphenyl affects the reaction [TJP1 protein binds to OCLN protein]

PMID:20064788 PMID:20299304 PMID:22906770

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

outer dynein arm docking complex subunit 4

decreases expression

2,3',4,4',5-pentachlorobiphenyl results in decreased expression of ODAD4 mRNA

NCBI chr10:85,480,089...85,508,603
Ensembl chr10:85,480,094...85,508,603

G

olfactory receptor 1057

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OR6C70 mRNA

NCBI chr 7:6,474,994...6,475,932
Ensembl chr 7:3,102,570...3,103,508

G

OPA1, mitochondrial dynamin like GTPase

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OPA1 mRNA

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

G

opioid receptor, delta 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OPRD1 mRNA

NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960

G

ORAI calcium release-activated calcium modulator 1

multiple interactions
increases expression

1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ORAI1 protein]

NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405

G

origin recognition complex, subunit 5

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of ORC5 mRNA

NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568

G

oxysterol binding protein-like 10

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OSBPL10 mRNA

NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625

G

organic solute carrier partner 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OSCP1 mRNA

NCBI chr 5:138,334,552...138,365,220
Ensembl chr 5:138,333,893...138,366,822

G

oxidative stress responsive serine-rich 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OSER1 mRNA

NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149

G

OTU deubiquitinase, ubiquitin aldehyde binding 1

increases expression

2,3',4,4',5-pentachlorobiphenyl results in increased expression of OTUB1 mRNA

NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483