The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5, 7 and 3' and methoxy groups at positions 6, 4' and 5' respectively.
irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN protein]
irigenin inhibits the reaction [TNF protein results in increased activity of and results in increased cleavage of CASP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of CASP3 mRNA]
irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 protein]
irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 protein]
irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 protein]
irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 protein]
irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN protein]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 protein]; irigenin inhibits the reaction [TNF protein results in increased activity of and results in increased cleavage of CASP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of CASP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
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