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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(S)-goitrin
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Accession:CHEBI:80751 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has S-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5S)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (-)-5-vinyl-2-oxazolidinethione;   (5S)-5-ethenyl-2-oxazolidinethione;   (S)-5-ethenyl-2-oxazolidinethione;   (S)-5-vinyloxazolidine-2-thione;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m0/s1;   InChIKey=UZQVYLOFLQICCT-BYPYZUCNSA-N;   L-5-vinyl-2-oxazolidinethione;   L-5-vinyl-2-thiooxazolidone;   L-goitrin;   SMILES=[H][C@@]1(CNC(=S)O1)C=C;   goitrin
 xref: CAS:500-12-9;   Chemspider:5885349;   KEGG:C16817
 xref_mesh: MESH:C004333
 xref: PMID:20551074;   PMID:22023255;   PMID:26946249;   PMID:27022502;   PMID:28894621;   PMID:31918015;   PMID:4100548;   PMID:4122716;   PMID:4177780;   PMID:4185966;   PMID:4186887;   PMID:4187735;   PMID:5038356;   PMID:59353;   PMID:5953555;   PMID:6092032;   PMID:6179840;   PMID:6723906;   PMID:7532609;   PMID:852785;   Patent:CN101445490;   Patent:CN101863850
 cyclic_relationship: is_enantiomer_of CHEBI:183228


show annotations for term's descendants           Sort by:
(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] CTD PMID:7532609 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
goitrin results in decreased expression of GSTP1 protein		 CTD PMID:7532609 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          antiviral agent 11343
            (S)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17795
                                    oxazolidines 5446
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (S)-goitrin 2
                                          (RS)-goitrin 2
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