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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,4,5,6-tetrahydropyrimidines
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Accession:CHEBI:78715 term browser browse the term
Definition:Any tetrahydropyrimidine in which the double bond is between positions 1 and 2.
Synonyms:related_synonym: Formula=C4N2R8;   SMILES=[*]N1C([*])=NC([*])([*])C([*])([*])C1([*])[*]


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pyrantel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Pyrantel results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing ISO CYP2D6 protein affects the metabolism of Pyrantel CTD PMID:12920490 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Pyrantel results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          nitrogen atom 18982
            nitrogen molecular entity 18982
              organonitrogen compound 18834
                organonitrogen heterocyclic compound 18154
                  tetrahydropyrimidine 3
                    1,4,5,6-tetrahydropyrimidines 3
                      5-hydroxyectoine 0
                      ectoine 0
                      nitensidine E 0
                      pyrantel 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            organic molecule 19713
                              organic cyclic compound 19505
                                organic heterocyclic compound 18875
                                  organonitrogen heterocyclic compound 18154
                                    tetrahydropyrimidine 3
                                      1,4,5,6-tetrahydropyrimidines 3
                                        5-hydroxyectoine 0
                                        ectoine 0
                                        nitensidine E 0
                                        pyrantel 3
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