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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,4,5,6-tetrahydropyrimidines
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Accession:CHEBI:78715 term browser browse the term
Definition:Any tetrahydropyrimidine in which the double bond is between positions 1 and 2.
Synonyms:related_synonym: Formula=C4N2R8;   SMILES=[*]N1C([*])=NC([*])([*])C([*])([*])C1([*])[*]



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pyrantel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP Pyrantel results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) affects metabolic processing EXP CYP2D6 protein affects the metabolism of Pyrantel CTD PMID:12920490 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity EXP Pyrantel results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26506
    chemical entity 26486
      atom 26482
        nonmetal atom 25745
          nitrogen atom 22717
            nitrogen molecular entity 22717
              organonitrogen compound 22120
                organonitrogen heterocyclic compound 20378
                  tetrahydropyrimidine 3
                    1,4,5,6-tetrahydropyrimidines 3
                      5-hydroxyectoine 0
                      ectoine 0
                      nitensidine E 0
                      pyrantel 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 26506
    subatomic particle 26482
      composite particle 26482
        hadron 26482
          baryon 26482
            nucleon 26482
              atomic nucleus 26482
                atom 26482
                  main group element atom 26220
                    p-block element atom 26220
                      carbon group element atom 25665
                        carbon atom 25627
                          organic molecular entity 25627
                            organic molecule 25371
                              organic cyclic compound 24429
                                organic heterocyclic compound 22431
                                  organonitrogen heterocyclic compound 20378
                                    tetrahydropyrimidine 3
                                      1,4,5,6-tetrahydropyrimidines 3
                                        5-hydroxyectoine 0
                                        ectoine 0
                                        nitensidine E 0
                                        pyrantel 3
paths to the root