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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,4,5,6-tetrahydropyrimidines
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Accession:CHEBI:78715 term browser browse the term
Definition:Any tetrahydropyrimidine in which the double bond is between positions 1 and 2.
Synonyms:related_synonym: Formula=C4N2R8;   SMILES=[*]N1C([*])=NC([*])([*])C([*])([*])C1([*])[*]



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pyrantel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Pyrantel results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing ISO CYP2D6 protein affects the metabolism of Pyrantel CTD PMID:12920490 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Pyrantel results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    chemical entity 19877
      atom 19877
        nonmetal atom 19800
          nitrogen atom 18979
            nitrogen molecular entity 18979
              organonitrogen compound 18834
                organonitrogen heterocyclic compound 18155
                  tetrahydropyrimidine 3
                    1,4,5,6-tetrahydropyrimidines 3
                      5-hydroxyectoine 0
                      ectoine 0
                      nitensidine E 0
                      pyrantel 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      carbon group element atom 19756
                        carbon atom 19753
                          organic molecular entity 19753
                            organic molecule 19706
                              organic cyclic compound 19498
                                organic heterocyclic compound 18878
                                  organonitrogen heterocyclic compound 18155
                                    tetrahydropyrimidine 3
                                      1,4,5,6-tetrahydropyrimidines 3
                                        5-hydroxyectoine 0
                                        ectoine 0
                                        nitensidine E 0
                                        pyrantel 3
paths to the root