CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: diallyl trisulfide
Accession: CHEBI:78492
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Definition: An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity
Synonyms: exact_synonym: diallyltrisulfane
related_synonym: (CH2=CHCH2S)2S; DATS; Formula=C6H10S3; InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2; InChIKey=UBAXRAHSPKWNCX-UHFFFAOYSA-N; SMILES=C=CCSSSCC=C; allyl trisulfide; di-2-propenyl trisulfide
xref: CAS:2050-87-5; HMDB:HMDB0031154
xref_mesh: MESH:C042577
xref: PMID:10757551; PMID:11020449; PMID:22020565; PMID:22137902; PMID:22143535; PMID:22525868; PMID:22578287; PMID:22595511; PMID:22736270; PMID:22919419; PMID:23073793; PMID:23139364; PMID:23412769; PMID:23430952; PMID:23453443; PMID:23811270; PMID:23859039; PMID:24084732; PMID:24295472; PMID:24309133; PMID:24415872; PMID:24440170; PMID:24460275; PMID:24487688; PMID:24489685; PMID:24557053; PMID:24788927; PMID:3791995; PMID:5135721; PMID:8024350; PMID:9654398; Reaxys:1745734; Wikipedia:Diallyl_trisulfide
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Abca1
ATP binding cassette subfamily A member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of ABCA1 mRNA
CTD
PMID:34995734
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression decreases expression
ISO
diallyl trisulfide results in increased expression of ABCB1 mRNA diallyl trisulfide results in decreased expression of ABCB1 protein
CTD
PMID:22397993 PMID:24788927
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
ISO
diallyl trisulfide results in increased expression of ABCC1 mRNA
CTD
PMID:22397993
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc3
ATP binding cassette subfamily C member 3
decreases expression increases expression
ISO
diallyl trisulfide results in decreased expression of ABCC3 mRNA diallyl trisulfide results in increased expression of ABCC3 mRNA
CTD
PMID:22397993 PMID:34995734
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
increases expression decreases expression
ISO
diallyl trisulfide results in increased expression of ABCC4 mRNA diallyl trisulfide results in decreased expression of ABCC4 mRNA
CTD
PMID:22397993
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcc6
ATP binding cassette subfamily C member 6
increases expression
ISO
diallyl trisulfide results in increased expression of ABCC6 mRNA
CTD
PMID:22397993
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Abcc9
ATP binding cassette subfamily C member 9
increases expression
ISO
diallyl trisulfide results in increased expression of ABCC9 mRNA
CTD
PMID:34995734
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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Acta2
actin alpha 2, smooth muscle
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of ACTA2 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of ACTA2 protein]
CTD
PMID:28157488
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actg1
actin, gamma 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of ACTG1 protein
CTD
PMID:19550292
NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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Actr1a
actin related protein 1A
increases expression
ISO
diallyl trisulfide results in increased expression of ACTR1A mRNA
CTD
PMID:34995734
NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495
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Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
increases expression
ISO
diallyl trisulfide results in increased expression of ADAMTS1 mRNA
CTD
PMID:34995734
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adgrg2
adhesion G protein-coupled receptor G2
increases expression
EXP
diallyl trisulfide results in increased expression of ADGRG2 mRNA
CTD
PMID:34014027
NCBI chr X:34,297,402...34,422,590
Ensembl chr X:34,297,402...34,422,609
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Adora2a
adenosine A2a receptor
increases expression
EXP
diallyl trisulfide results in increased expression of ADORA2A mRNA
CTD
PMID:34014027
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Adra2c
adrenoceptor alpha 2C
decreases expression
EXP
diallyl trisulfide results in decreased expression of ADRA2C mRNA
CTD
PMID:34014027
NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846
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Ahnak2
AHNAK nucleoprotein 2
increases expression
ISO
diallyl trisulfide results in increased expression of AHNAK2 mRNA
CTD
PMID:34995734
NCBI chr 6:131,830,668...131,876,311
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Ak2
adenylate kinase 2
increases expression
ISO
diallyl trisulfide results in increased expression of AK2 protein
CTD
PMID:16344271
NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
diallyl trisulfide results in increased expression of AKR1C1 mRNA
CTD
PMID:34995734
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akt1
AKT serine/threonine kinase 1
multiple interactions decreases expression increases phosphorylation decreases phosphorylation
EXP ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] diallyl trisulfide results in decreased expression of AKT1 mRNA; diallyl trisulfide results in decreased expression of AKT1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; diallyl trisulfide results in decreased expression of and results in decreased phosphorylation of AKT1 protein; Iodoacetamide inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]
CTD
PMID:19823037 PMID:22020565 PMID:23453443 PMID:23663050 PMID:23754639 PMID:24415872 PMID:24489685 PMID:27566995 PMID:33751676 More...
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alad
aminolevulinate dehydratase
increases activity multiple interactions
EXP
diallyl trisulfide results in increased activity of ALAD protein diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of ALAD protein]
CTD
PMID:25062976
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Alas2
5'-aminolevulinate synthase 2
increases expression
EXP
diallyl trisulfide results in increased expression of ALAS2 mRNA
CTD
PMID:34014027
NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
multiple interactions decreases expression
ISO
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein] diallyl trisulfide results in decreased expression of ALDH1A1 protein
CTD
PMID:29626521 PMID:33751676
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Alpl
alkaline phosphatase, biomineralization associated
increases expression
ISO
diallyl trisulfide results in increased expression of ALPL protein
CTD
PMID:19550292
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Ampd3
adenosine monophosphate deaminase 3
increases expression
ISO
diallyl trisulfide results in increased expression of AMPD3 mRNA
CTD
PMID:34995734
NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
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Angptl4
angiopoietin-like 4
multiple interactions increases expression
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] diallyl trisulfide results in increased expression of ANGPTL4 mRNA
CTD
PMID:28574600 PMID:34995734
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Anln
anillin, actin binding protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of ANLN mRNA
CTD
PMID:34995734
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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Anxa1
annexin A1
increases expression
ISO
diallyl trisulfide results in increased expression of ANXA1 mRNA; diallyl trisulfide results in increased expression of ANXA1 protein
CTD
PMID:16344271
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa8
annexin A8
increases expression
EXP
diallyl trisulfide results in increased expression of ANXA8 mRNA
CTD
PMID:34014027
NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
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Aox1
aldehyde oxidase 1
increases expression
ISO
diallyl trisulfide results in increased expression of AOX1 mRNA
CTD
PMID:34995734
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Apba1
amyloid beta precursor protein binding family A member 1
increases expression
ISO
diallyl trisulfide results in increased expression of APBA1 mRNA
CTD
PMID:34995734
NCBI chr 1:221,363,769...221,569,496
Ensembl chr 1:221,363,778...221,566,553
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Aph1b
aph-1 homolog B, gamma secretase subunit
increases expression
ISO
diallyl trisulfide results in increased expression of APH1B mRNA
CTD
PMID:34995734
NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
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Apln
apelin
decreases expression
EXP
diallyl trisulfide results in decreased expression of APLN mRNA
CTD
PMID:34014027
NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391
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Ar
androgen receptor
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of AR mRNA; diallyl trisulfide results in decreased expression of AR protein diallyl trisulfide inhibits the reaction [Metribolone affects the localization of AR protein]
CTD
PMID:19622577
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arhgap32
Rho GTPase activating protein 32
increases expression
EXP
diallyl trisulfide results in increased expression of ARHGAP32 mRNA
CTD
PMID:34014027
NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454
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Arl6ip1
ADP-ribosylation factor like GTPase 6 interacting protein 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of ARL6IP1 mRNA
CTD
PMID:34995734
NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
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Aspm
assembly factor for spindle microtubules
decreases expression
ISO
diallyl trisulfide results in decreased expression of ASPM mRNA
CTD
PMID:34995734
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
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Atp13a3
ATPase 13A3
increases expression
ISO
diallyl trisulfide results in increased expression of ATP13A3 mRNA
CTD
PMID:34995734
NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235
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Atp2b4
ATPase plasma membrane Ca2+ transporting 4
increases expression
ISO
diallyl trisulfide results in increased expression of ATP2B4 mRNA
CTD
PMID:34995734
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
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Atp5pd
ATP synthase peripheral stalk subunit d
decreases expression increases expression
ISO
diallyl trisulfide results in decreased expression of ATP5PD protein diallyl trisulfide results in increased expression of ATP5PD protein
CTD
PMID:16344271
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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Aurka
aurora kinase A
decreases expression
ISO
diallyl trisulfide results in decreased expression of AURKA mRNA
CTD
PMID:34995734
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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Aurkb
aurora kinase B
decreases expression
ISO
diallyl trisulfide results in decreased expression of AURKB mRNA
CTD
PMID:34995734
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bach1
BTB domain and CNC homolog 1
increases expression
ISO
diallyl trisulfide results in increased expression of BACH1 mRNA
CTD
PMID:34995734
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Bad
BCL2-associated agonist of cell death
decreases phosphorylation
ISO
diallyl trisulfide results in decreased phosphorylation of BAD protein
CTD
PMID:27566995
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Bak1
BCL2-antagonist/killer 1
increases expression increases activity multiple interactions
ISO
diallyl trisulfide results in increased expression of BAK1 protein diallyl trisulfide results in increased activity of BAK1 protein SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]
CTD
PMID:17513609 PMID:23412769
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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Batf3
basic leucine zipper ATF-like transcription factor 3
increases expression
ISO
diallyl trisulfide results in increased expression of BATF3 mRNA
CTD
PMID:34995734
NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
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Bax
BCL2 associated X, apoptosis regulator
increases expression increases activity multiple interactions
ISO EXP
diallyl trisulfide results in increased expression of BAX mRNA; diallyl trisulfide results in increased expression of BAX protein diallyl trisulfide results in increased activity of BAX protein diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of BAX protein] diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein]
CTD
PMID:19823037 PMID:23412769 PMID:23754639 PMID:24415872 PMID:24460275 PMID:29087013 PMID:31115753 More...
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbc3
Bcl-2 binding component 3
increases expression
ISO
diallyl trisulfide results in increased expression of BBC3 mRNA; diallyl trisulfide results in increased expression of BBC3 protein
CTD
PMID:24460275
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions
ISO EXP
diallyl trisulfide results in decreased expression of BCL2; diallyl trisulfide results in decreased expression of BCL2 mRNA; diallyl trisulfide results in decreased expression of BCL2 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein] diallyl trisulfide inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]
CTD
PMID:17513609 PMID:19823037 PMID:20055834 PMID:22578287 PMID:22595511 PMID:23754639 PMID:24415872 PMID:24460275 PMID:25205294 PMID:29087013 PMID:31115753 More...
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of BCL2L1 protein
CTD
PMID:17513609 PMID:20055834
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bdkrb2
bradykinin receptor B2
decreases expression
ISO
diallyl trisulfide results in decreased expression of BDKRB2 mRNA
CTD
PMID:34995734
NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
diallyl trisulfide results in decreased expression of BID protein
CTD
PMID:22578287
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Birc2
baculoviral IAP repeat-containing 2
increases expression decreases expression
ISO
diallyl trisulfide results in increased expression of BIRC2 protein diallyl trisulfide results in decreased expression of BIRC2 protein
CTD
PMID:21411500 PMID:22578287
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc5
baculoviral IAP repeat-containing 5
increases expression decreases expression
ISO
diallyl trisulfide results in increased expression of BIRC5 protein diallyl trisulfide results in increased expression of BIRC5 mRNA; diallyl trisulfide results in increased expression of BIRC5 protein diallyl trisulfide results in decreased expression of BIRC5 mRNA; diallyl trisulfide results in decreased expression of BIRC5 protein
CTD
PMID:21411500 PMID:23754639 PMID:34995734
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bivm
basic, immunoglobulin-like variable motif containing
increases expression
ISO
diallyl trisulfide results in increased expression of BIVM mRNA
CTD
PMID:34995734
NCBI chr 9:46,268,758...46,305,038
Ensembl chr 9:46,269,252...46,305,024
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Bmi1
BMI1 proto-oncogene, polycomb ring finger
affects expression
ISO
diallyl trisulfide affects the expression of BMI1 protein
CTD
PMID:27129776
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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Brsk1
BR serine/threonine kinase 1
increases expression
ISO
diallyl trisulfide results in increased expression of BRSK1 mRNA
CTD
PMID:34995734
NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365
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Btf3
basic transcription factor 3
increases expression
ISO
diallyl trisulfide results in increased expression of BTF3 protein
CTD
PMID:16344271
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
diallyl trisulfide results in decreased expression of BUB1 mRNA
CTD
PMID:34995734
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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C11h3orf52
similar to human chromosome 3 open reading frame 52
increases expression
ISO
diallyl trisulfide results in increased expression of C3ORF52 mRNA
CTD
PMID:34995734
NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292
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C4a
complement C4A
increases expression
EXP
diallyl trisulfide results in increased expression of C4A mRNA
CTD
PMID:34014027
NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
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Calr
calreticulin
increases expression
ISO
diallyl trisulfide results in increased expression of CALR protein
CTD
PMID:19550292
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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Capza1
capping actin protein of muscle Z-line subunit alpha 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of CAPZA1 protein
CTD
PMID:16344271
NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
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Casp1
caspase 1
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of CASP1 protein]
CTD
PMID:36796188
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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Casp3
caspase 3
increases activity increases expression multiple interactions increases cleavage decreases activity
ISO EXP
diallyl trisulfide results in increased activity of CASP3 protein diallyl trisulfide results in increased expression of CASP3 mRNA diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]] diallyl trisulfide results in increased cleavage of CASP3 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein] diallyl trisulfide results in decreased activity of CASP3 protein
CTD
PMID:20055834 PMID:21574149 PMID:22578287 PMID:22595511 PMID:23453443 PMID:23754639 PMID:24295472 PMID:25062976 PMID:25205294 PMID:25896937 PMID:27566995 PMID:28571773 PMID:29087013 PMID:31115753 PMID:34995734 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases activity increases cleavage multiple interactions
ISO
diallyl trisulfide results in increased activity of CASP8 protein diallyl trisulfide results in increased cleavage of CASP8 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]
CTD
PMID:22578287 PMID:22595511 PMID:28571773
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Casp9
caspase 9
multiple interactions increases activity increases cleavage
ISO
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein] diallyl trisulfide results in increased activity of CASP9 protein
CTD
PMID:20055834 PMID:22578287 PMID:22595511 PMID:28571773
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of CAT protein]
CTD
PMID:24295472 PMID:25062976
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cav1
caveolin 1
multiple interactions
ISO
diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]
CTD
PMID:20229525
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
G
Ccdc34
coiled-coil domain containing 34
decreases expression
ISO
diallyl trisulfide results in decreased expression of CCDC34 mRNA
CTD
PMID:34995734
NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146
G
Ccl2
C-C motif chemokine ligand 2
decreases expression decreases secretion multiple interactions
ISO
diallyl trisulfide results in decreased expression of CCL2 mRNA diallyl trisulfide results in decreased secretion of CCL2 protein diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]
CTD
PMID:34848446 PMID:34995734
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccna2
cyclin A2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CCNA2 mRNA; diallyl trisulfide results in decreased expression of CCNA2 protein
CTD
PMID:34995734
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
G
Ccnb1
cyclin B1
increases expression multiple interactions affects localization decreases expression
ISO
diallyl trisulfide results in increased expression of CCNB1 protein diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein] diallyl trisulfide affects the localization of CCNB1 protein diallyl trisulfide results in decreased expression of CCNB1 mRNA; diallyl trisulfide results in decreased expression of CCNB1 protein
CTD
PMID:19823037 PMID:20143254 PMID:24415872 PMID:34995734
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
G
Ccnb2
cyclin B2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CCNB2 mRNA
CTD
PMID:34995734
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
G
Ccnd1
cyclin D1
decreases expression increases expression
ISO
diallyl trisulfide results in decreased expression of CCND1 mRNA; diallyl trisulfide results in decreased expression of CCND1 protein diallyl trisulfide results in increased expression of CCND1 mRNA; diallyl trisulfide results in increased expression of CCND1 protein
CTD
PMID:14693049 PMID:19823037 PMID:23430952 PMID:24415872
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Ccnf
cyclin F
decreases expression
ISO
diallyl trisulfide results in decreased expression of CCNF mRNA
CTD
PMID:34995734
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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Cd274
CD274 molecule
increases expression
ISO
diallyl trisulfide results in increased expression of CD274 mRNA
CTD
PMID:34995734
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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Cd44
CD44 molecule
decreases expression
ISO
diallyl trisulfide results in decreased expression of CD44 protein
CTD
PMID:33751676
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
G
Cd70
Cd70 molecule
decreases expression
ISO
diallyl trisulfide results in decreased expression of CD70 mRNA
CTD
PMID:34995734
NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
G
Cdc20
cell division cycle 20
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDC20 mRNA
CTD
PMID:34995734
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
G
Cdc25b
cell division cycle 25B
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDC25B mRNA
CTD
PMID:34995734
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
G
Cdc25c
cell division cycle 25C
multiple interactions decreases expression
ISO
diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDC25C protein; diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein; EUK-134 inhibits the reaction [diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein] diallyl trisulfide results in decreased expression of CDC25C protein
CTD
PMID:16707465 PMID:20143254 PMID:23754639
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
G
Cdca2
cell division cycle associated 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDCA2 mRNA
CTD
PMID:34995734
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
G
Cdca3
cell division cycle associated 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDCA3 mRNA
CTD
PMID:34995734
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
G
Cdca8
cell division cycle associated 8
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDCA8 mRNA
CTD
PMID:34995734
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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Cdh1
cadherin 1
multiple interactions increases expression
ISO
SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]
CTD
PMID:23412769
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
G
Cdk1
cyclin-dependent kinase 1
multiple interactions affects localization decreases expression
ISO
diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDK1 protein diallyl trisulfide affects the localization of CDK1 protein diallyl trisulfide results in decreased expression of CDK1 mRNA; diallyl trisulfide results in decreased expression of CDK1 protein
CTD
PMID:20143254 PMID:23754639 PMID:34995734
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
diallyl trisulfide results in increased expression of CDKN1A mRNA; diallyl trisulfide results in increased expression of CDKN1A protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]
CTD
PMID:16222732 PMID:17937621 PMID:23754639 PMID:24415872 PMID:29626521
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression
ISO
diallyl trisulfide results in increased expression of CDKN1B protein
CTD
PMID:14693049
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2c
cyclin-dependent kinase inhibitor 2C
decreases expression
ISO
diallyl trisulfide results in decreased expression of CDKN2C mRNA
CTD
PMID:34995734
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
G
Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
ISO EXP
diallyl trisulfide results in decreased expression of CDKN3 mRNA
CTD
PMID:34014027 PMID:34995734
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
G
Cebpa
CCAAT/enhancer binding protein alpha
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of CEBPA mRNA; diallyl trisulfide results in decreased expression of CEBPA protein [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]
CTD
PMID:22137902
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
G
Cebpb
CCAAT/enhancer binding protein beta
multiple interactions decreases expression
ISO
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein] diallyl trisulfide results in decreased expression of CEBPB mRNA; diallyl trisulfide results in decreased expression of CEBPB protein
CTD
PMID:22137902
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
G
Cenpa
centromere protein A
decreases expression
ISO
diallyl trisulfide results in decreased expression of CENPA mRNA
CTD
PMID:34995734
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
G
Cenpe
centromere protein E
decreases expression
ISO
diallyl trisulfide results in decreased expression of CENPE mRNA
CTD
PMID:34995734
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
G
Cenpf
centromere protein F
decreases expression
ISO
diallyl trisulfide results in decreased expression of CENPF mRNA
CTD
PMID:34995734
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
G
Cenpm
centromere protein M
decreases expression
ISO
diallyl trisulfide results in decreased expression of CENPM mRNA
CTD
PMID:34995734
NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258
G
Cep55
centrosomal protein 55
decreases expression
ISO
diallyl trisulfide results in decreased expression of CEP55 mRNA
CTD
PMID:34995734
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
G
Ces2c
carboxylesterase 2C
decreases expression
EXP
diallyl trisulfide results in decreased expression of CES2C mRNA
CTD
PMID:34014027
NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
G
Cfb
complement factor B
increases expression
EXP
diallyl trisulfide results in increased expression of CFB mRNA
CTD
PMID:34014027
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfl1
cofilin 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of CFL1 protein
CTD
PMID:16344271
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
G
Cflar
CASP8 and FADD-like apoptosis regulator
decreases expression increases expression
ISO
diallyl trisulfide results in decreased expression of CFLAR protein diallyl trisulfide results in increased expression of CFLAR mRNA
CTD
PMID:25205294 PMID:34995734
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
G
Cit
citron rho-interacting serine/threonine kinase
decreases expression
ISO
diallyl trisulfide results in decreased expression of CIT mRNA
CTD
PMID:34995734
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
G
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
increases expression
ISO
diallyl trisulfide results in increased expression of CITED2 mRNA
CTD
PMID:34995734
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
G
Ckap2
cytoskeleton associated protein 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CKAP2 mRNA
CTD
PMID:34995734
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
G
Ckap2l
cytoskeleton associated protein 2-like
decreases expression
ISO
diallyl trisulfide results in decreased expression of CKAP2L mRNA
CTD
PMID:34995734
NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366
G
Cks1b
CDC28 protein kinase regulatory subunit 1B
decreases expression
ISO
diallyl trisulfide results in decreased expression of CKS1B mRNA
CTD
PMID:34995734
NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
G
Cks2
CDC28 protein kinase regulatory subunit 2
decreases expression
EXP
diallyl trisulfide results in decreased expression of CKS2 mRNA
CTD
PMID:34014027
NCBI chr17:13,570,611...13,575,770
G
Cldn1
claudin 1
decreases expression increases expression
ISO
diallyl trisulfide results in decreased expression of CLDN1 mRNA; diallyl trisulfide results in decreased expression of CLDN1 protein diallyl trisulfide results in increased expression of CLDN1 mRNA
CTD
PMID:24084732 PMID:34995734
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
G
Cldn12
claudin 12
increases expression
ISO
diallyl trisulfide results in increased expression of CLDN12 mRNA
CTD
PMID:34995734
NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
G
Cldn2
claudin 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CLDN2 mRNA; diallyl trisulfide results in decreased expression of CLDN2 protein
CTD
PMID:24084732
NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
G
Cldn3
claudin 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of CLDN3 mRNA; diallyl trisulfide results in decreased expression of CLDN3 protein
CTD
PMID:24084732
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
G
Cldn4
claudin 4
decreases expression
ISO
diallyl trisulfide results in decreased expression of CLDN4 mRNA; diallyl trisulfide results in decreased expression of CLDN4 protein
CTD
PMID:24084732
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
G
Cldn5
claudin 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of CLDN5 mRNA; diallyl trisulfide results in decreased expression of CLDN5 protein
CTD
PMID:24084732
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
G
Clmp
CXADR-like membrane protein
increases expression
ISO
diallyl trisulfide results in increased expression of CLMP mRNA
CTD
PMID:34995734
NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838
G
Clptm1l
CLPTM1-like
increases expression
ISO
diallyl trisulfide results in increased expression of CLPTM1L mRNA
CTD
PMID:34995734
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
G
Clu
clusterin
increases expression
ISO
diallyl trisulfide results in increased expression of CLU mRNA
CTD
PMID:34995734
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Cmklr2
chemerin chemokine-like receptor 2
increases expression
ISO
diallyl trisulfide results in increased expression of CMKLR2 mRNA
CTD
PMID:34995734
NCBI chr 9:64,583,310...64,617,883
Ensembl chr 9:64,585,594...64,586,655
G
Cntn3
contactin 3
increases expression
ISO
diallyl trisulfide results in increased expression of CNTN3 mRNA
CTD
PMID:34995734
NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:134,842,266...135,125,613
G
Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
diallyl trisulfide results in decreased expression of COL1A1 mRNA
CTD
PMID:34995734
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Col5a3
collagen type V alpha 3 chain
decreases expression
ISO
diallyl trisulfide results in decreased expression of COL5A3 mRNA
CTD
PMID:34995734
NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
G
Col8a1
collagen type VIII alpha 1 chain
decreases expression
ISO
diallyl trisulfide results in decreased expression of COL8A1 mRNA
CTD
PMID:34995734
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
G
Coro2b
coronin 2B
increases expression
ISO
diallyl trisulfide results in increased expression of CORO2B mRNA
CTD
PMID:34995734
NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
G
Coro7
coronin 7
increases expression
ISO
diallyl trisulfide results in increased expression of CORO7 mRNA
CTD
PMID:34995734
NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001
G
Creb3l2
cAMP responsive element binding protein 3-like 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of CREB3L2 mRNA
CTD
PMID:34995734
NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
G
Creb5
cAMP responsive element binding protein 5
increases expression
ISO
diallyl trisulfide results in increased expression of CREB5 mRNA
CTD
PMID:34995734
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
G
Crebrf
CREB3 regulatory factor
increases expression
ISO
diallyl trisulfide results in increased expression of CREBRF mRNA
CTD
PMID:34995734
NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
G
Csf2
colony stimulating factor 2
increases expression
ISO
diallyl trisulfide results in increased expression of CSF2 mRNA
CTD
PMID:34995734
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csf3
colony stimulating factor 3
increases expression
ISO
diallyl trisulfide results in increased expression of CSF3 mRNA
CTD
PMID:34995734
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Cstb
cystatin B
decreases expression
ISO
diallyl trisulfide results in decreased expression of CSTB protein
CTD
PMID:16344271
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
G
Ctnnb1
catenin beta 1
increases cleavage decreases phosphorylation multiple interactions decreases expression
ISO
diallyl trisulfide results in increased cleavage of CTNNB1 protein diallyl trisulfide results in decreased phosphorylation of CTNNB1 protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein] diallyl trisulfide results in decreased expression of CTNNB1 protein
CTD
PMID:22578287 PMID:23663050 PMID:29626521
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
G
Cul3
cullin 3
decreases expression
EXP
diallyl trisulfide results in decreased expression of CUL3 protein
CTD
PMID:23453443
NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
G
Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
diallyl trisulfide results in increased expression of CXCL2 mRNA
CTD
PMID:34995734
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cyba
cytochrome b-245 alpha chain
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBA protein]
CTD
PMID:29087013
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
G
Cybb
cytochrome b-245 beta chain
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBB protein]
CTD
PMID:29087013
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
G
Cybrd1
cytochrome b reductase 1
increases expression
EXP
diallyl trisulfide results in increased expression of CYBRD1 mRNA
CTD
PMID:34014027
NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein]
CTD
PMID:31115753
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
EXP
diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein]
CTD
PMID:28115069
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]
CTD
PMID:28115069
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein]
CTD
PMID:28115069
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression multiple interactions
EXP
diallyl trisulfide results in decreased expression of CYP2E1 protein diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]
CTD
PMID:28115069
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of CYP7A1 mRNA
CTD
PMID:16382202
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cystm1
cysteine-rich transmembrane module containing 1
increases expression
ISO
diallyl trisulfide results in increased expression of CYSTM1 mRNA
CTD
PMID:34995734
NCBI chr18:27,945,862...28,013,509
Ensembl chr18:27,951,653...28,013,510
G
Dach1
dachshund family transcription factor 1
increases expression multiple interactions
ISO
diallyl trisulfide results in increased expression of DACH1 mRNA FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]
CTD
PMID:27129776
NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
G
Dazap2
DAZ associated protein 2
increases expression
ISO
diallyl trisulfide results in increased expression of DAZAP2 mRNA
CTD
PMID:34995734
NCBI chr 7:131,714,749...131,720,266
Ensembl chr 7:131,714,745...131,720,265
G
Ddit4l
DNA-damage-inducible transcript 4-like
increases expression
EXP
diallyl trisulfide results in increased expression of DDIT4L mRNA
CTD
PMID:34014027
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
G
Ddt
D-dopachrome tautomerase
decreases expression
ISO
diallyl trisulfide results in decreased expression of DDT protein
CTD
PMID:16344271
NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
G
Depdc1
DEP domain containing 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of DEPDC1 mRNA
CTD
PMID:34995734
NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
G
Depdc1b
DEP domain containing 1B
decreases expression
ISO
diallyl trisulfide results in decreased expression of DEPDC1B mRNA
CTD
PMID:34995734
NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
G
Des
desmin
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein]
CTD
PMID:28157488
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
G
Dffa
DNA fragmentation factor subunit alpha
increases degradation
ISO
diallyl trisulfide results in increased degradation of DFFA protein
CTD
PMID:23754639
NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
G
Dhfr
dihydrofolate reductase
decreases expression
ISO
diallyl trisulfide results in decreased expression of DHFR mRNA
CTD
PMID:34995734
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
G
Dhrs3
dehydrogenase/reductase 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of DHRS3 mRNA
CTD
PMID:34995734
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
G
Diras1
DIRAS family GTPase 1
increases expression
ISO
diallyl trisulfide results in increased expression of DIRAS1 mRNA
CTD
PMID:34995734
NCBI chr 7:8,687,964...8,692,828
Ensembl chr 7:8,687,942...8,693,831
G
Disp1
dispatched RND transporter family member 1
increases expression
EXP
diallyl trisulfide results in increased expression of DISP1 mRNA
CTD
PMID:34014027
NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702
G
Dlgap5
DLG associated protein 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of DLGAP5 mRNA
CTD
PMID:34995734
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
G
Dnajc27
DnaJ heat shock protein family (Hsp40) member C27
decreases expression
ISO
diallyl trisulfide results in decreased expression of DNAJC27 protein
CTD
PMID:19550292
NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449
G
Dnm1l
dynamin 1-like
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein]
CTD
PMID:31115753
NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
G
Duox1
dual oxidase 1
increases expression
EXP
diallyl trisulfide results in increased expression of DUOX1 mRNA
CTD
PMID:34014027
NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
diallyl trisulfide results in increased expression of DUSP1 mRNA
CTD
PMID:34995734
NCBI chr10:16,680,478...16,683,275
G
Dusp5
dual specificity phosphatase 5
increases expression
ISO
diallyl trisulfide results in increased expression of DUSP5 mRNA
CTD
PMID:34995734
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
G
Dynlrb1
dynein light chain roadblock-type 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of DYNLRB1 protein
CTD
PMID:19550292
NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:143,742,586...143,764,227
G
Efemp1
EGF containing fibulin extracellular matrix protein 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of EFEMP1 mRNA
CTD
PMID:34995734
NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
G
Egfr
epidermal growth factor receptor
decreases expression
ISO
diallyl trisulfide results in decreased expression of EGFR protein
CTD
PMID:23754639
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Egln3
egl-9 family hypoxia-inducible factor 3
increases expression
EXP
diallyl trisulfide results in increased expression of EGLN3 mRNA
CTD
PMID:34014027
NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
G
Eif4h
eukaryotic translation initiation factor 4H
decreases expression
ISO
diallyl trisulfide results in decreased expression of EIF4H protein
CTD
PMID:16344271
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
G
Eno1
enolase 1
increases expression
ISO
diallyl trisulfide results in increased expression of ENO1 protein
CTD
PMID:16344271
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Epgn
epithelial mitogen
increases expression
ISO
diallyl trisulfide results in increased expression of EPGN mRNA
CTD
PMID:34995734
NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
G
Ephb1
Eph receptor B1
increases expression
ISO
diallyl trisulfide results in increased expression of EPHB1 mRNA
CTD
PMID:34995734
NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839
G
Ephx1
epoxide hydrolase 1
increases expression
EXP
diallyl trisulfide results in increased expression of EPHX1 mRNA
CTD
PMID:20650352
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Ereg
epiregulin
increases expression
ISO
diallyl trisulfide results in increased expression of EREG mRNA
CTD
PMID:34995734
NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
G
Esm1
endothelial cell-specific molecule 1
increases expression
ISO
diallyl trisulfide results in increased expression of ESM1 mRNA
CTD
PMID:34995734
NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
G
Espl1
extra spindle pole bodies like 1, separase
decreases expression
ISO
diallyl trisulfide results in decreased expression of ESPL1 mRNA
CTD
PMID:34995734
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
G
Etv1
ETS variant transcription factor 1
increases expression
EXP
diallyl trisulfide results in increased expression of ETV1 mRNA
CTD
PMID:34014027
NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
G
F2r
coagulation factor II (thrombin) receptor
decreases expression
ISO
diallyl trisulfide results in decreased expression of F2R mRNA
CTD
PMID:34995734
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
G
F3
coagulation factor III, tissue factor
multiple interactions decreases activity
ISO
diallyl trisulfide inhibits the reaction [ICAM1 protein results in increased expression of F3 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of F3 protein]; diallyl trisulfide inhibits the reaction [VCAM1 protein results in increased expression of F3 mRNA] diallyl trisulfide results in decreased activity of F3 protein
CTD
PMID:35022635
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Fam83d
family with sequence similarity 83, member D
decreases expression
ISO
diallyl trisulfide results in decreased expression of FAM83D mRNA
CTD
PMID:34995734
NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
G
Fas
Fas cell surface death receptor
increases expression
ISO
diallyl trisulfide results in increased expression of FAS mRNA; diallyl trisulfide results in increased expression of FAS protein
CTD
PMID:19823037 PMID:24415872
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fasn
fatty acid synthase
multiple interactions decreases expression
ISO EXP
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN diallyl trisulfide results in decreased expression of FASN mRNA
CTD
PMID:22137902 PMID:34014027
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fbln1
fibulin 1
increases expression
EXP
diallyl trisulfide results in increased expression of FBLN1 mRNA
CTD
PMID:34014027
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
G
Fbxo10
F-box protein 10
increases expression
EXP
diallyl trisulfide results in increased expression of FBXO10 mRNA
CTD
PMID:34014027
NCBI chr 5:59,297,016...59,343,429
Ensembl chr 5:59,297,045...59,343,348
G
Fgf2
fibroblast growth factor 2
increases expression
ISO
diallyl trisulfide results in increased expression of FGF2 mRNA
CTD
PMID:34995734
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
G
Fgf21
fibroblast growth factor 21
decreases expression
EXP
diallyl trisulfide results in decreased expression of FGF21 mRNA
CTD
PMID:34014027
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
G
Flnc
filamin C
increases expression
EXP
diallyl trisulfide results in increased expression of FLNC mRNA
CTD
PMID:34014027
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
G
Fndc4
fibronectin type III domain containing 4
increases expression
ISO
diallyl trisulfide results in increased expression of FNDC4 mRNA
CTD
PMID:34995734
NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675
G
Folr1
folate receptor alpha
increases expression
ISO
diallyl trisulfide results in increased expression of FOLR1 mRNA
CTD
PMID:11925593
NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
affects localization
ISO
diallyl trisulfide affects the localization of FOS protein
CTD
PMID:25927362
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxd1
forkhead box D1
increases expression
ISO
diallyl trisulfide results in increased expression of FOXD1 mRNA
CTD
PMID:34995734
NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978
G
Foxg1
forkhead box G1
increases expression
ISO
diallyl trisulfide results in increased expression of FOXG1 mRNA
CTD
PMID:34995734
NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
G
Foxm1
forkhead box M1
decreases expression
ISO
diallyl trisulfide results in decreased expression of FOXM1 mRNA
CTD
PMID:34995734
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
G
Foxp3
forkhead box P3
decreases expression
ISO
diallyl trisulfide results in decreased expression of FOXP3 mRNA
CTD
PMID:20979868
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
G
Foxq1
forkhead box Q1
multiple interactions decreases expression
ISO
diallyl trisulfide results in decreased expression of and affects the localization of FOXQ1 protein; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA] diallyl trisulfide results in decreased expression of FOXQ1 mRNA
CTD
PMID:27129776
NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 Ensembl chr17:32,912,744...32,915,377
G
Frzb
frizzled-related protein
increases expression
EXP
diallyl trisulfide results in increased expression of FRZB mRNA
CTD
PMID:34014027
NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
G
Fth1
ferritin heavy chain 1
multiple interactions increases expression
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein diallyl trisulfide results in increased expression of FTH1 mRNA
CTD
PMID:16707465 PMID:34995734
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
multiple interactions increases expression
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] diallyl trisulfide results in increased expression of FTL mRNA
CTD
PMID:16707465 PMID:34995734
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Ftmt
ferritin mitochondrial
multiple interactions decreases expression
ISO
[diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]
CTD
PMID:21616139
NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
G
Fubp1
far upstream element binding protein 1
increases expression
ISO
diallyl trisulfide results in increased expression of FUBP1 protein
CTD
PMID:16344271
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
G
G0s2
G0/G1switch 2
increases expression
ISO
diallyl trisulfide results in increased expression of G0S2 mRNA
CTD
PMID:34995734
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of G6PD protein]
CTD
PMID:25062976
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gabarapl1
GABA type A receptor associated protein like 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of GABARAPL1 mRNA
CTD
PMID:34995734
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
diallyl trisulfide results in increased expression of GADD45A mRNA
CTD
PMID:17937621
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
decreases expression
ISO
diallyl trisulfide results in decreased expression of GAPDH protein
CTD
PMID:16344271
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO EXP
diallyl trisulfide results in increased expression of GCLC mRNA
CTD
PMID:34014027 PMID:34887701
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
diallyl trisulfide results in increased expression of GCLM mRNA
CTD
PMID:34887701
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdnf
glial cell derived neurotrophic factor
increases expression
ISO
diallyl trisulfide results in increased expression of GDNF mRNA
CTD
PMID:34995734
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
G
Gem
GTP binding protein overexpressed in skeletal muscle
increases expression
ISO
diallyl trisulfide results in increased expression of GEM mRNA
CTD
PMID:34995734
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
G
Golm2
golgi membrane protein 2
increases expression
EXP
diallyl trisulfide results in increased expression of CASC4 mRNA
CTD
PMID:34014027
NCBI chr 3:108,827,017...108,896,207
Ensembl chr 3:108,827,047...108,896,207
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of GPT protein]
CTD
PMID:25062976
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gsap
gamma-secretase activating protein
increases expression
ISO
diallyl trisulfide results in increased expression of GSAP mRNA
CTD
PMID:34995734
NCBI chr 4:13,813,046...13,907,875
Ensembl chr 4:13,813,046...13,907,814
G
Gsk3b
glycogen synthase kinase 3 beta
decreases expression increases phosphorylation
EXP ISO
diallyl trisulfide results in decreased expression of GSK3B protein diallyl trisulfide results in increased phosphorylation of GSK3B protein diallyl trisulfide results in decreased expression of GSK3B protein modified form
CTD
PMID:23453443 PMID:23663050 PMID:29626521
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsr
glutathione-disulfide reductase
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of GSR protein]
CTD
PMID:25062976
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gsta1
glutathione S-transferase alpha 1
increases expression
EXP
diallyl trisulfide results in increased expression of GSTA1 mRNA
CTD
PMID:34014027
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta5
glutathione S-transferase alpha 5
increases expression
EXP
diallyl trisulfide results in increased expression of GSTA5 mRNA
CTD
PMID:20650352
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstp1
glutathione S-transferase pi 1
decreases expression multiple interactions increases expression
ISO EXP
diallyl trisulfide results in decreased expression of GSTP1 mRNA; diallyl trisulfide results in decreased expression of GSTP1 protein [diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; [diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and results in increased activity of GSTP1 protein diallyl trisulfide results in increased expression of GSTP1 mRNA
CTD
PMID:16344271 PMID:20237067
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gtse1
G-2 and S-phase expressed 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of GTSE1 mRNA
CTD
PMID:34995734
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
G
Gulp1
GULP PTB domain containing engulfment adaptor 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of GULP1 mRNA
CTD
PMID:34995734
NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
G
H1f2
H1.2 linker histone, cluster member
decreases expression
ISO
diallyl trisulfide results in decreased expression of H1-2 mRNA
CTD
PMID:34995734
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
G
H2ax
H2A.X variant histone
decreases expression
ISO
diallyl trisulfide results in decreased expression of H2AX mRNA
CTD
PMID:34995734
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
G
H2az1
H2A.Z variant histone 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of H2AZ1 mRNA
CTD
PMID:34995734
NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485
G
H2az2
H2A.Z variant histone 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of H2AZ2 mRNA
CTD
PMID:34995734
NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144
G
Has2
hyaluronan synthase 2
increases expression
ISO
diallyl trisulfide results in increased expression of HAS2 mRNA
CTD
PMID:34995734
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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Hbe2
hemoglobin, epsilon 2
increases expression
EXP
diallyl trisulfide results in increased expression of HBE2 mRNA
CTD
PMID:34014027
NCBI chr 1:158,279,285...158,280,913
Ensembl chr 1:158,279,285...158,280,913
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Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
diallyl trisulfide results in increased expression of HBEGF mRNA
CTD
PMID:34995734
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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Hbq1b
hemoglobin subunit theta 1B
increases expression
EXP
diallyl trisulfide results in increased expression of HBQ1B mRNA
CTD
PMID:34014027
NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397 Ensembl chr10:15,320,762...15,321,397
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Hdac9
histone deacetylase 9
increases expression
ISO
diallyl trisulfide results in increased expression of HDAC9 mRNA
CTD
PMID:34995734
NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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Hes1
hes family bHLH transcription factor 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of HES1 mRNA
CTD
PMID:23430952 PMID:34995734
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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Hey1
hes-related family bHLH transcription factor with YRPW motif 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of HEY1 mRNA
CTD
PMID:23430952
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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Hey2
hes-related family bHLH transcription factor with YRPW motif 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of HEY2 mRNA
CTD
PMID:23430952
NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions decreases expression
ISO
diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] diallyl trisulfide results in decreased expression of HIF1A protein diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of HIF1A mRNA]
CTD
PMID:28574600 PMID:36796188
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
diallyl trisulfide results in increased expression of HIPK2 mRNA
CTD
PMID:34995734
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
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Hivep2
HIVEP zinc finger 2
increases expression
ISO
diallyl trisulfide results in increased expression of HIVEP2 mRNA
CTD
PMID:34995734
NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
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Hjurp
Holliday junction recognition protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of HJURP mRNA
CTD
PMID:34995734
NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
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Hlx
H2.0-like homeobox
increases expression
ISO
diallyl trisulfide results in increased expression of HLX mRNA
CTD
PMID:34995734
NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
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Hmgb2
high mobility group box 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of HMGB2 mRNA
CTD
PMID:34995734
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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Hmgn2
high mobility group nucleosomal binding domain 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of HMGN2 mRNA
CTD
PMID:34995734
NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521 Ensembl chr16:146,192,126...146,195,521
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Hmmr
hyaluronan-mediated motility receptor
decreases expression
ISO
diallyl trisulfide results in decreased expression of HMMR mRNA
CTD
PMID:34995734
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO EXP
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] diallyl trisulfide results in increased expression of HMOX1 mRNA; diallyl trisulfide results in increased expression of HMOX1 protein NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]; [diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
CTD
PMID:23412769 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 PMID:34887701 PMID:34995734 More...
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnf4a
hepatocyte nuclear factor 4, alpha
increases expression
ISO
diallyl trisulfide results in increased expression of HNF4A mRNA
CTD
PMID:16382202
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
decreases expression
ISO
diallyl trisulfide results in decreased expression of HNRNPA2B1 protein
CTD
PMID:16344271
NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
increases expression
ISO
diallyl trisulfide results in increased expression of HNRNPDL protein
CTD
PMID:16344271
NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506
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Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
increases expression
ISO
diallyl trisulfide results in increased expression of HNRNPH1 protein
CTD
PMID:16344271
NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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Hspa12a
heat shock protein family A (Hsp70) member 12A
decreases expression
ISO
diallyl trisulfide results in decreased expression of HSPA12A mRNA
CTD
PMID:34995734
NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of HSPA5 protein
CTD
PMID:19550292
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
diallyl trisulfide results in increased expression of HSPA6 mRNA
CTD
PMID:34995734
NCBI chr13:83,273,176...83,274,317
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Hspa8
heat shock protein family A (Hsp70) member 8
decreases expression
ISO
diallyl trisulfide results in decreased expression of HSPA8 protein
CTD
PMID:19550292
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Hspa9
heat shock protein family A (Hsp70) member 9
decreases expression
ISO
diallyl trisulfide results in decreased expression of HSPA9 protein
CTD
PMID:19550292
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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Hspb8
heat shock protein family B (small) member 8
increases expression
EXP
diallyl trisulfide results in increased expression of HSPB8 mRNA
CTD
PMID:34014027
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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Hspd1
heat shock protein family D (Hsp60) member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of HSPD1 protein
CTD
PMID:19550292
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Hyls1
HYLS1, centriolar and ciliogenesis associated
decreases expression
ISO
diallyl trisulfide results in decreased expression of HYLS1 mRNA
CTD
PMID:34995734
NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760
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Hyou1
hypoxia up-regulated 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of HYOU1 protein
CTD
PMID:19550292
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [ICAM1 protein results in increased expression of F3 mRNA]
CTD
PMID:35022635
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Ier2
immediate early response 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of IER2 mRNA
CTD
PMID:34995734
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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Ifi44l
interferon-induced protein 44-like
decreases expression
ISO
diallyl trisulfide results in decreased expression of IFI44L mRNA
CTD
PMID:34995734
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of IFIT3 mRNA
CTD
PMID:34995734
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Igfbp3
insulin-like growth factor binding protein 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of IGFBP3 mRNA
CTD
PMID:34995734
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Ikbke
inhibitor of nuclear factor kappa B kinase subunit epsilon
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of IKBKE mRNA]
CTD
PMID:34848446
NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
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Il10
interleukin 10
multiple interactions
ISO
diallyl trisulfide results in decreased expression of and results in decreased secretion of IL10 protein
CTD
PMID:20979868
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il11
interleukin 11
increases expression
ISO
diallyl trisulfide results in increased expression of IL11 mRNA
CTD
PMID:34995734
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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Il12a
interleukin 12A
increases expression
ISO
diallyl trisulfide results in increased expression of IL12A mRNA
CTD
PMID:34995734
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il13ra2
interleukin 13 receptor subunit alpha 2
increases expression
ISO
diallyl trisulfide results in increased expression of IL13RA2 mRNA
CTD
PMID:34995734
NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381
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Il1b
interleukin 1 beta
multiple interactions
ISO
[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of and results in increased secretion of IL1B protein]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of IL1B mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]
CTD
PMID:25500681 PMID:36796188
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il24
interleukin 24
increases expression
ISO
diallyl trisulfide results in increased expression of IL24 mRNA
CTD
PMID:34995734
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Il4r
interleukin 4 receptor
increases expression
ISO
diallyl trisulfide results in increased expression of IL4R mRNA
CTD
PMID:34995734
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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Il6
interleukin 6
increases expression multiple interactions
ISO EXP
diallyl trisulfide results in increased expression of IL6 mRNA diallyl trisulfide inhibits the reaction [Arsenic results in increased expression of IL6 protein]
CTD
PMID:25062976 PMID:34995734
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ina
internexin neuronal intermediate filament protein, alpha
increases expression
ISO
diallyl trisulfide results in increased expression of INA protein
CTD
PMID:19550292
NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
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Incenp
inner centromere protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of INCENP mRNA
CTD
PMID:34995734
NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265
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Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
diallyl trisulfide results in increased expression of IRAK2 mRNA
CTD
PMID:34995734
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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Itga4
integrin subunit alpha 4
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGA4 protein
CTD
PMID:28741790
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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Itga5
integrin subunit alpha 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGA5 protein
CTD
PMID:28741790
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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Itgav
integrin subunit alpha V
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGAV protein
CTD
PMID:28741790
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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Itgb1
integrin subunit beta 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGB1 protein
CTD
PMID:28741790
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Itgb3
integrin subunit beta 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGB3 protein
CTD
PMID:28741790
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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Itgb4
integrin subunit beta 4
decreases expression
ISO
diallyl trisulfide results in decreased expression of ITGB4 protein
CTD
PMID:28741790
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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Jag1
jagged canonical Notch ligand 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of JAG1 mRNA
CTD
PMID:34995734
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation multiple interactions increases expression increases activity affects localization
ISO EXP
diallyl trisulfide results in increased phosphorylation of JUN protein diallyl trisulfide inhibits the reaction [TNF protein affects the localization of JUN protein modified form]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein] [diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer] diallyl trisulfide results in increased expression of JUN protein diallyl trisulfide results in increased activity of JUN protein diallyl trisulfide affects the localization of JUN protein
CTD
PMID:16707465 PMID:20237067 PMID:25927362 PMID:35022635
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kcna5
potassium voltage-gated channel subfamily A member 5
decreases activity
ISO
diallyl trisulfide results in decreased activity of KCNA5 protein
CTD
PMID:23272117
NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
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Kcnd3
potassium voltage-gated channel subfamily D member 3
multiple interactions
ISO
diallyl trisulfide binds to and results in decreased activity of KCND3 protein
CTD
PMID:23272117
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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Kcnh2
potassium voltage-gated channel subfamily H member 2
multiple interactions decreases activity
ISO
diallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein diallyl trisulfide results in decreased activity of KCNH2 protein
CTD
PMID:23272117 PMID:24504171
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Keap1
Kelch-like ECH-associated protein 1
decreases expression multiple interactions affects binding
EXP ISO
diallyl trisulfide results in decreased expression of KEAP1 protein diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein] diallyl trisulfide binds to KEAP1 protein
CTD
PMID:23453443 PMID:24489685
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Kif11
kinesin family member 11
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF11 mRNA
CTD
PMID:34995734
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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Kif14
kinesin family member 14
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF14 mRNA
CTD
PMID:34995734
NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
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Kif15
kinesin family member 15
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF15 mRNA
CTD
PMID:34995734
NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
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Kif18b
kinesin family member 18B
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF18B mRNA
CTD
PMID:34995734
NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
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Kif20a
kinesin family member 20A
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF20A mRNA
CTD
PMID:34995734
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Kif22
kinesin family member 22
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF22 mRNA
CTD
PMID:34995734
NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
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Kif23
kinesin family member 23
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF23 mRNA
CTD
PMID:34995734
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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Kif2c
kinesin family member 2C
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF2C mRNA
CTD
PMID:34995734
NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
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Kif4a
kinesin family member 4A
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIF4A mRNA
CTD
PMID:34995734
NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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Kifc1
kinesin family member C1
decreases expression
ISO
diallyl trisulfide results in decreased expression of KIFC1 mRNA
CTD
PMID:34995734
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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Kit
KIT proto-oncogene receptor tyrosine kinase
increases expression
ISO
diallyl trisulfide results in increased expression of KIT protein
CTD
PMID:23663050
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Klb
klotho beta
increases expression
EXP
diallyl trisulfide results in increased expression of KLB mRNA
CTD
PMID:34014027
NCBI chr14:42,899,050...42,950,788
Ensembl chr14:42,899,510...42,950,799
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Knl1
kinetochore scaffold 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of KNL1 mRNA
CTD
PMID:34995734
NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
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Knstrn
kinetochore-localized astrin/SPAG5 binding protein
decreases expression
ISO EXP
diallyl trisulfide results in decreased expression of KNSTRN mRNA
CTD
PMID:34014027 PMID:34995734
NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
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Kpna2
karyopherin subunit alpha 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of KPNA2 mRNA
CTD
PMID:34995734
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
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Krt10
keratin 10
increases expression
ISO
diallyl trisulfide results in increased expression of KRT10 protein
CTD
PMID:19550292
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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Krt34
keratin 34
increases expression
ISO
diallyl trisulfide results in increased expression of KRT34 mRNA
CTD
PMID:34995734
NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040
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Krt8
keratin 8
decreases expression
ISO
diallyl trisulfide results in decreased expression of KRT8 protein
CTD
PMID:16344271
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Krtap1-1
keratin associated protein 1-1
increases expression
ISO
diallyl trisulfide results in increased expression of KRTAP1-5 mRNA
CTD
PMID:34995734
NCBI chr10:84,545,765...84,546,331
Ensembl chr10:84,545,580...84,546,354
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Krtap4-3
keratin associated protein 4-3
increases expression
ISO
diallyl trisulfide results in increased expression of KRTAP4-8 mRNA
CTD
PMID:34995734
NCBI chr10:84,752,173...84,790,523
Ensembl chr10:84,789,628...84,790,527
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L1cam
L1 cell adhesion molecule
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM mRNA]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM protein]
CTD
PMID:28574600
NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
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Lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
increases expression
ISO
diallyl trisulfide results in increased expression of LAMTOR5 mRNA
CTD
PMID:11925594
NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
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Ldha
lactate dehydrogenase A
multiple interactions decreases expression decreases response to substance
ISO
LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein] diallyl trisulfide results in decreased expression of LDHA mRNA; diallyl trisulfide results in decreased expression of LDHA protein LDHA protein results in decreased susceptibility to diallyl trisulfide
CTD
PMID:27566995 PMID:34995734
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Lep
leptin
decreases expression
EXP
diallyl trisulfide results in decreased expression of LEP mRNA
CTD
PMID:34014027
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
diallyl trisulfide results in increased expression of LIF mRNA
CTD
PMID:34995734
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lmnb1
lamin B1
decreases expression
ISO
diallyl trisulfide results in decreased expression of LMNB1 mRNA
CTD
PMID:34995734
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lonrf1
LON peptidase N-terminal domain and ring finger 1
increases expression
ISO
diallyl trisulfide results in increased expression of LONRF1 mRNA
CTD
PMID:34995734
NCBI chr16:55,984,572...56,015,156
Ensembl chr16:55,984,463...56,015,156
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Lox
lysyl oxidase
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA]
CTD
PMID:28574600
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Loxl4
lysyl oxidase-like 4
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOXL4 mRNA]
CTD
PMID:28574600
NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
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Lpar1
lysophosphatidic acid receptor 1
increases expression
EXP
diallyl trisulfide results in increased expression of LPAR1 mRNA
CTD
PMID:34014027
NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
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Lrrc39
leucine rich repeat containing 39
decreases expression
EXP
diallyl trisulfide results in decreased expression of LRRC39 mRNA
CTD
PMID:34014027
NCBI chr 2:204,516,122...204,535,463
Ensembl chr 2:204,516,123...204,535,463
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Lrrc8a
leucine rich repeat containing 8 VRAC subunit A
increases expression
EXP
diallyl trisulfide results in increased expression of LRRC8A mRNA
CTD
PMID:34014027
NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202
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Lypd6b
Ly6/Plaur domain containing 6B
decreases expression
ISO
diallyl trisulfide results in decreased expression of LYPD6B mRNA
CTD
PMID:34995734
NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770
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Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
increases expression
EXP
diallyl trisulfide results in increased expression of LYVE1 mRNA
CTD
PMID:34014027
NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
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Mad2l1
mitotic arrest deficient 2 like 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of MAD2L1 mRNA
CTD
PMID:34995734
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
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Map2k4
mitogen activated protein kinase kinase 4
multiple interactions
ISO
MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]
CTD
PMID:16707465
NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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Map2k7
mitogen activated protein kinase kinase 7
affects expression multiple interactions
ISO
diallyl trisulfide affects the expression of MAP2K7 protein MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein]
CTD
PMID:16707465 PMID:21695758
NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
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Map3k14
mitogen-activated protein kinase kinase kinase 14
decreases expression
ISO
diallyl trisulfide results in decreased expression of MAP3K14 mRNA
CTD
PMID:34995734
NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
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Map3k3
mitogen activated protein kinase kinase kinase 3
affects expression
ISO
diallyl trisulfide affects the expression of MAP3K3 protein
CTD
PMID:21695758
NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
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Map3k7cl
MAP3K7 C-terminal like
increases expression
ISO
diallyl trisulfide results in increased expression of MAP3K7CL mRNA
CTD
PMID:34995734
NCBI chr11:26,791,044...26,835,605
Ensembl chr11:26,791,316...26,835,602
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Mapk1
mitogen activated protein kinase 1
multiple interactions decreases expression increases phosphorylation decreases phosphorylation
ISO EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein] diallyl trisulfide results in decreased expression of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein] diallyl trisulfide results in decreased phosphorylation of MAPK1 protein
CTD
PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 More...
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
decreases expression multiple interactions increases phosphorylation decreases phosphorylation
ISO EXP
diallyl trisulfide results in decreased expression of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein] diallyl trisulfide results in decreased phosphorylation of MAPK3 protein
CTD
PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 More...
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of MAPK8 mRNA]
CTD
PMID:34848446
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mcl1
MCL1 apoptosis regulator, BCL2 family member
decreases expression
ISO
diallyl trisulfide results in decreased expression of MCL1 protein
CTD
PMID:28571773
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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Mcm7
minichromosome maintenance complex component 7
decreases expression
ISO
diallyl trisulfide results in decreased expression of MCM7 mRNA
CTD
PMID:34995734
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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Mdm2
MDM2 proto-oncogene
decreases expression increases degradation
ISO
diallyl trisulfide results in decreased expression of MDM2 protein diallyl trisulfide results in increased degradation of MDM2 protein
CTD
PMID:23754639 PMID:24415872
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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Med29
mediator complex subunit 29
increases expression
ISO
diallyl trisulfide results in increased expression of MED29 mRNA
CTD
PMID:34995734
NCBI chr 1:83,677,961...83,683,365
Ensembl chr 1:83,677,961...83,683,365
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Mest
mesoderm specific transcript
decreases expression
ISO
diallyl trisulfide results in decreased expression of MEST mRNA
CTD
PMID:34995734
NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
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Metrnl
meteorin-like, glial cell differentiation regulator
increases expression
ISO
diallyl trisulfide results in increased expression of METRNL mRNA
CTD
PMID:34995734
NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
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Mgat4b
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
increases expression
ISO
diallyl trisulfide results in increased expression of MGAT4B mRNA
CTD
PMID:34995734
NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229
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Mgll
monoglyceride lipase
increases expression
ISO
diallyl trisulfide results in increased expression of MGLL mRNA
CTD
PMID:34995734
NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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Mid1
midline 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of MID1 mRNA
CTD
PMID:34995734
NCBI chr X:24,116,674...24,491,205
Ensembl chr X:24,120,293...24,248,353
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Mir125b1
microRNA 125b-1
increases expression
EXP
diallyl trisulfide results in increased expression of MIR125B1
CTD
PMID:34014027
NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
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Mir143
microRNA 143
increases expression
ISO
diallyl trisulfide results in increased expression of MIR143 mRNA
CTD
PMID:23430952
NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
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Mir144
microRNA 144
increases expression
EXP
diallyl trisulfide results in increased expression of MIR144
CTD
PMID:34014027
NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
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Mir145
microRNA 145
increases expression
ISO
diallyl trisulfide results in increased expression of MIR145 mRNA
CTD
PMID:23430952
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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Mir200b
microRNA 200b
increases expression
ISO
diallyl trisulfide results in increased expression of MIR200B mRNA
CTD
PMID:23430952
NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
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Mir200c
microRNA 200c
increases expression
ISO
diallyl trisulfide results in increased expression of MIR200C mRNA
CTD
PMID:23430952
NCBI chr 4:157,523,679...157,523,747
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Mir21
microRNA 21
decreases expression
ISO
diallyl trisulfide results in decreased expression of MIR21 mRNA
CTD
PMID:23430952
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir221
microRNA 221
decreases expression
ISO
diallyl trisulfide results in decreased expression of MIR221 mRNA
CTD
PMID:23663050
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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Mir290
microRNA 290
increases expression
EXP
diallyl trisulfide results in increased expression of MIR290
CTD
PMID:34014027
NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728
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Mki67
marker of proliferation Ki-67
decreases expression
ISO
diallyl trisulfide results in decreased expression of MKI67 mRNA
CTD
PMID:34995734
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp11
matrix metallopeptidase 11
increases expression
EXP
diallyl trisulfide results in increased expression of MMP11 mRNA
CTD
PMID:34014027
NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
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Mmp2
matrix metallopeptidase 2
multiple interactions decreases activity decreases expression
ISO
diallyl trisulfide results in decreased expression of and results in decreased activity of MMP2 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein] diallyl trisulfide results in decreased expression of MMP2 mRNA; diallyl trisulfide results in decreased expression of MMP2 protein
CTD
PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28574600 PMID:28741790 PMID:30396169 More...
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
diallyl trisulfide results in increased expression of MMP3 mRNA
CTD
PMID:34995734
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp7
matrix metallopeptidase 7
decreases expression
ISO
diallyl trisulfide results in decreased expression of MMP7 protein
CTD
PMID:21695758
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp9
matrix metallopeptidase 9
multiple interactions affects expression decreases activity decreases expression
ISO
diallyl trisulfide results in decreased expression of and results in decreased activity of MMP9 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein] diallyl trisulfide affects the expression of MMP9 protein diallyl trisulfide results in decreased expression of MMP9 mRNA; diallyl trisulfide results in decreased expression of MMP9 protein
CTD
PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28741790 PMID:30396169 More...
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mrpl30
mitochondrial ribosomal protein L30
decreases expression
ISO
diallyl trisulfide results in decreased expression of MRPL30 mRNA
CTD
PMID:34995734
NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257
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Mt-co1
mitochondrially encoded cytochrome c oxidase I
decreases expression
ISO
diallyl trisulfide results in decreased expression of COX1 mRNA
CTD
PMID:34995734
NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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Mt-co2
mitochondrially encoded cytochrome c oxidase II
decreases expression
ISO
diallyl trisulfide results in decreased expression of COX2 mRNA
CTD
PMID:34995734
NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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Mt-nd5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of ND5 mRNA
CTD
PMID:34995734
NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
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Mtor
mechanistic target of rapamycin kinase
decreases expression
ISO
diallyl trisulfide results in decreased expression of MTOR protein
CTD
PMID:23754639
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mxd3
Max dimerization protein 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of MXD3 mRNA
CTD
PMID:34995734
NCBI chr17:9,301,430...9,305,156
Ensembl chr17:9,301,399...9,305,157
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Mybl2
MYB proto-oncogene like 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of MYBL2 mRNA
CTD
PMID:34995734
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of MYC mRNA; diallyl trisulfide results in decreased expression of MYC protein FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]
CTD
PMID:23754639 PMID:27129776 PMID:29626521
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myd88
MYD88, innate immune signal transduction adaptor
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein]
CTD
PMID:25500681
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Nabp1
nucleic acid binding protein 1
increases expression
ISO
diallyl trisulfide results in increased expression of NABP1 mRNA
CTD
PMID:34995734
NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
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Nanog
Nanog homeobox
decreases expression multiple interactions increases expression
ISO
diallyl trisulfide results in decreased expression of NANOG mRNA; diallyl trisulfide results in decreased expression of NANOG protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein] diallyl trisulfide results in increased expression of NANOG protein
CTD
PMID:29626521 PMID:33751676
NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
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Ncapd2
non-SMC condensin I complex, subunit D2
decreases expression
ISO
diallyl trisulfide results in decreased expression of NCAPD2 mRNA
CTD
PMID:34995734
NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
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Ncapg2
non-SMC condensin II complex, subunit G2
decreases expression
ISO
diallyl trisulfide results in decreased expression of NCAPG2 mRNA
CTD
PMID:34995734
NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159
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Ncaph
non-SMC condensin I complex, subunit H
decreases expression
ISO
diallyl trisulfide results in decreased expression of NCAPH mRNA
CTD
PMID:34995734
NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
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Ncf1
neutrophil cytosolic factor 1
decreases expression
EXP
diallyl trisulfide results in decreased expression of NCF1 protein
CTD
PMID:29087013
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Ncf2
neutrophil cytosolic factor 2
increases expression
ISO
diallyl trisulfide results in increased expression of NCF2 mRNA
CTD
PMID:34887701
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ndc80
NDC80 kinetochore complex component
decreases expression
ISO
diallyl trisulfide results in decreased expression of NDC80 mRNA
CTD
PMID:34995734
NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
diallyl trisulfide results in increased expression of NDRG1 mRNA
CTD
PMID:17937621
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Neil3
nei-like DNA glycosylase 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of NEIL3 mRNA
CTD
PMID:34995734
NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
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Nek2
NIMA-related kinase 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of NEK2 mRNA
CTD
PMID:34995734
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
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Neurl1b
neuralized E3 ubiquitin protein ligase 1B
decreases expression
ISO
diallyl trisulfide results in decreased expression of NEURL1B mRNA
CTD
PMID:34995734
NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions increases expression increases activity increases localization
EXP ISO
[diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein] diallyl trisulfide results in increased expression of NFE2L2 mRNA; diallyl trisulfide results in increased expression of NFE2L2 protein diallyl trisulfide results in increased activity of NFE2L2 protein Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; Dithiothreitol inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein] diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] diallyl trisulfide results in increased localization of NFE2L2 protein
CTD
PMID:18768114 PMID:20237067 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 More...
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkbia
NFKB inhibitor alpha
decreases phosphorylation decreases degradation increases phosphorylation increases expression
ISO
diallyl trisulfide results in decreased phosphorylation of NFKBIA protein diallyl trisulfide results in decreased degradation of NFKBIA protein diallyl trisulfide results in increased phosphorylation of NFKBIA protein diallyl trisulfide results in increased expression of NFKBIA mRNA; diallyl trisulfide results in increased expression of NFKBIA protein
CTD
PMID:23663050 PMID:24788927 PMID:25205294 PMID:25927362
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nfkbiz
NFKB inhibitor zeta
increases expression
ISO
diallyl trisulfide results in increased expression of NFKBIZ mRNA
CTD
PMID:34995734
NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
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Nipa1
NIPA magnesium transporter 1
increases expression
ISO
diallyl trisulfide results in increased expression of NIPA1 mRNA
CTD
PMID:34995734
NCBI chr 1:106,834,000...106,875,148
Ensembl chr 1:106,834,000...106,874,790
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Nkx2-1
NK2 homeobox 1
increases expression
ISO
diallyl trisulfide results in increased expression of NKX2-1 protein
CTD
PMID:33751676
NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
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Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] affects the localization of NLRP3 protein]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]]
CTD
PMID:36796188
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nos2
nitric oxide synthase 2
affects expression multiple interactions
ISO
diallyl trisulfide affects the expression of NOS2 protein diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
CTD
PMID:21695758 PMID:25500681
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
multiple interactions decreases degradation increases phosphorylation increases expression
ISO
diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl trisulfide results in increased phosphorylation of NOS3 protein] diallyl trisulfide results in decreased degradation of NOS3 protein diallyl trisulfide results in increased expression of NOS3 protein
CTD
PMID:20229525
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Notch1
notch receptor 1
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of NOTCH1 mRNA; diallyl trisulfide results in decreased expression of NOTCH1 protein NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]
CTD
PMID:23430952
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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Notch3
notch receptor 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of NOTCH3 mRNA
CTD
PMID:34995734
NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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Nox3
NADPH oxidase 3
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX3 mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX3 protein]
CTD
PMID:36796188
NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851
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Nox4
NADPH oxidase 4
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 protein]
CTD
PMID:36796188
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
EXP ISO
diallyl trisulfide results in increased expression of NQO1 mRNA diallyl trisulfide results in increased expression of NQO1 mRNA; diallyl trisulfide results in increased expression of NQO1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]
CTD
PMID:20650352 PMID:24489685 PMID:30317421
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f1
nuclear receptor subfamily 2, group F, member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of NR2F1 mRNA
CTD
PMID:34995734
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
diallyl trisulfide results in increased expression of NR4A1 mRNA
CTD
PMID:34995734
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nrgn
neurogranin
decreases expression
ISO
diallyl trisulfide results in decreased expression of NRGN mRNA
CTD
PMID:34995734
NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
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Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
increases expression
ISO
diallyl trisulfide results in increased expression of NSMF mRNA
CTD
PMID:34995734
NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
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Nucb1
nucleobindin 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of NUCB1 protein
CTD
PMID:19550292
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
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Nuf2
NUF2 component of NDC80 kinetochore complex
decreases expression
ISO
diallyl trisulfide results in decreased expression of NUF2 mRNA
CTD
PMID:34995734
NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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Nusap1
nucleolar and spindle associated protein 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of NUSAP1 mRNA
CTD
PMID:34995734
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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Ogdh
oxoglutarate dehydrogenase
multiple interactions
EXP
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of OGDH protein]
CTD
PMID:24295472
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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Olr1523
olfactory receptor 1523
increases expression
EXP
diallyl trisulfide results in increased expression of OLR1523 mRNA
CTD
PMID:34014027
NCBI chr10:72,708,272...72,709,213
Ensembl chr10:72,707,063...72,715,311
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Ophn1
oligophrenin 1
increases expression
ISO
diallyl trisulfide results in increased expression of OPHN1 mRNA
CTD
PMID:34995734
NCBI chr X:63,599,746...63,976,678
Ensembl chr X:63,603,042...63,976,633
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Osr2
odd-skipped related transciption factor 2
increases expression
EXP
diallyl trisulfide results in increased expression of OSR2 mRNA
CTD
PMID:34014027
NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224
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Otulinl
OTU deubiquitinase with linear linkage specificity like
decreases expression
ISO
diallyl trisulfide results in decreased expression of OTULINL mRNA
CTD
PMID:34995734
NCBI chr 2:78,405,994...78,433,860
Ensembl chr 2:78,408,593...78,433,838
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Pakap
paralemmin A kinase anchor protein
increases expression
ISO
diallyl trisulfide results in increased expression of PALM2AKAP2 mRNA
CTD
PMID:34995734
NCBI chr 5:72,536,986...72,648,524 NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
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Panx2
pannexin 2
increases expression
ISO
diallyl trisulfide results in increased expression of PANX2 mRNA
CTD
PMID:34995734
NCBI chr 7:120,139,259...120,153,056
Ensembl chr 7:120,139,294...120,152,361
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions
ISO
diallyl trisulfide results in increased cleavage of PARP1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]
CTD
PMID:20055834 PMID:22578287 PMID:25205294
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Parpbp
PARP1 binding protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of PARPBP mRNA
CTD
PMID:34995734
NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
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Pax8
paired box 8
increases expression
ISO
diallyl trisulfide results in increased expression of PAX8 protein
CTD
PMID:33751676
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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Pbk
PDZ binding kinase
decreases expression
ISO
diallyl trisulfide results in decreased expression of PBK mRNA
CTD
PMID:34995734
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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Pcdh18
protocadherin 18
decreases expression
ISO
diallyl trisulfide results in decreased expression of PCDH18 mRNA
CTD
PMID:34995734
NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883
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Pcdhga2
protocadherin gamma subfamily A, 2
increases expression
ISO
diallyl trisulfide results in increased expression of PCDHGA2 mRNA
CTD
PMID:34995734
NCBI chr18:29,493,954...29,667,865
Ensembl chr18:29,493,954...29,667,868
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Pclaf
PCNA clamp associated factor
decreases expression
ISO
diallyl trisulfide results in decreased expression of PCLAF mRNA
CTD
PMID:34995734
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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Pcna
proliferating cell nuclear antigen
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of PCNA protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]
CTD
PMID:29626521
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdgfrb
platelet derived growth factor receptor beta
decreases expression
ISO
diallyl trisulfide results in decreased expression of PDGFRB mRNA
CTD
PMID:34995734
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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Pex19
peroxisomal biogenesis factor 19
decreases expression
ISO
diallyl trisulfide results in decreased expression of PEX19 mRNA
CTD
PMID:34995734
NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
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Pfn2
profilin 2
increases expression
EXP
diallyl trisulfide results in increased expression of PFN2 mRNA
CTD
PMID:34014027
NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
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Pgk1
phosphoglycerate kinase 1
increases expression
ISO
diallyl trisulfide results in increased expression of PGK1 protein
CTD
PMID:16344271
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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Phf19
PHD finger protein 19
decreases expression
ISO
diallyl trisulfide results in decreased expression of PHF19 mRNA
CTD
PMID:34995734
NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405
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Piezo2
piezo-type mechanosensitive ion channel component 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of PIEZO2 mRNA
CTD
PMID:34995734
NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216
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Pif1
PIF1 5'-to-3' DNA helicase
decreases expression
ISO
diallyl trisulfide results in decreased expression of PIF1 mRNA
CTD
PMID:34995734
NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
multiple interactions
EXP
PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein]
CTD
PMID:25896937
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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Pimreg
PICALM interacting mitotic regulator
decreases expression
ISO
diallyl trisulfide results in decreased expression of PIMREG mRNA
CTD
PMID:34995734
NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791
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Plaur
plasminogen activator, urokinase receptor
affects expression
ISO
diallyl trisulfide affects the expression of PLAUR protein
CTD
PMID:27129776
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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Plcb4
phospholipase C, beta 4
increases expression
ISO
diallyl trisulfide results in increased expression of PLCB4 mRNA
CTD
PMID:34995734
NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
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Plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
increases expression
ISO
diallyl trisulfide results in increased expression of PLCXD1 mRNA
CTD
PMID:34995734
NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392
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Plin3
perilipin 3
increases expression
ISO
diallyl trisulfide results in increased expression of PLIN3 protein
CTD
PMID:16344271
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
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Plk1
polo-like kinase 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of PLK1 mRNA
CTD
PMID:34995734
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
increases expression
EXP
diallyl trisulfide results in increased expression of PLOD2 mRNA
CTD
PMID:34014027
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
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Poc1a
POC1 centriolar protein A
decreases expression
ISO
diallyl trisulfide results in decreased expression of POC1A mRNA
CTD
PMID:34995734
NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089
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Popdc3
popeye domain containing 3
increases expression
ISO
diallyl trisulfide results in increased expression of POPDC3 mRNA
CTD
PMID:34995734
NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593
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Pou5f1
POU class 5 homeobox 1
multiple interactions decreases expression
ISO
[diallyl trisulfide results in increased abundance of Hydrogen Sulfide] which results in increased expression of POU5F1 mRNA diallyl trisulfide results in decreased expression of POU5F1 mRNA; diallyl trisulfide results in decreased expression of POU5F1 protein
CTD
PMID:33180827 PMID:33751676
NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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Ppara
peroxisome proliferator activated receptor alpha
increases expression
ISO EXP
diallyl trisulfide results in increased expression of PPARA mRNA
CTD
PMID:16382202 PMID:34014027
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
decreases activity multiple interactions decreases expression
ISO
diallyl trisulfide results in decreased activity of PPARG protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in decreased expression of and results in decreased activity of PPARG protein]; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein] diallyl trisulfide results in decreased expression of PPARG mRNA; diallyl trisulfide results in decreased expression of PPARG protein
CTD
PMID:22137902
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
EXP
diallyl trisulfide results in increased expression of PPARGC1A mRNA
CTD
PMID:34014027
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
diallyl trisulfide results in increased expression of PPP1R15A mRNA
CTD
PMID:34995734
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Prc1
protein regulator of cytokinesis 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of PRC1 mRNA
CTD
PMID:34995734
NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
increases expression
EXP
diallyl trisulfide results in increased expression of PRKAA2 mRNA
CTD
PMID:34014027
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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Prom1
prominin 1
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of PROM1 protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein]
CTD
PMID:29626521 PMID:33751676
NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
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Prr11
proline rich 11
decreases expression
ISO
diallyl trisulfide results in decreased expression of PRR11 mRNA
CTD
PMID:34995734
NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
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Psma1
proteasome 20S subunit alpha 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of PSMA1 protein
CTD
PMID:19550292
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
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Psrc1
proline and serine rich coiled-coil 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of PSRC1 mRNA
CTD
PMID:34995734
NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
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Ptbp1
polypyrimidine tract binding protein 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of PTBP1 mRNA
CTD
PMID:34995734
NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
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Ptbp3
polypyrimidine tract binding protein 3
increases expression
EXP
diallyl trisulfide results in increased expression of PTBP3 mRNA
CTD
PMID:34014027
NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
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Ptgs2
prostaglandin-endoperoxide synthase 2
affects expression decreases expression multiple interactions increases expression
ISO
diallyl trisulfide affects the expression of PTGS2 protein diallyl trisulfide results in decreased expression of PTGS2 mRNA diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] diallyl trisulfide results in increased expression of PTGS2 mRNA
CTD
PMID:15523159 PMID:21695758 PMID:25500681 PMID:34995734
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptk2
protein tyrosine kinase 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of PTK2 protein; diallyl trisulfide results in decreased expression of PTK2 protein modified form
CTD
PMID:28741790
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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Ptpro
protein tyrosine phosphatase, receptor type, O
increases expression
ISO
diallyl trisulfide results in increased expression of PTPRO mRNA
CTD
PMID:34995734
NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
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Pttg1
PTTG1 regulator of sister chromatid separation, securin
decreases expression
ISO
diallyl trisulfide results in decreased expression of PTTG1 mRNA
CTD
PMID:34995734
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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Pycard
PYD and CARD domain containing
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to PYCARD protein]]
CTD
PMID:36796188
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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Pygo1
pygopus family PHD finger 1
increases expression
ISO
diallyl trisulfide results in increased expression of PYGO1 mRNA
CTD
PMID:34995734
NCBI chr 8:73,666,210...73,684,873
Ensembl chr 8:73,665,593...73,684,869
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Racgap1
Rac GTPase-activating protein 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of RACGAP1 mRNA
CTD
PMID:34995734
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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Raver1
ribonucleoprotein, PTB-binding 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of RAVER1 mRNA
CTD
PMID:34995734
NCBI chr 8:19,610,464...19,629,188
Ensembl chr 8:19,610,466...19,629,152
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Rbms2
RNA binding motif, single stranded interacting protein 2
increases expression
ISO
diallyl trisulfide results in increased expression of RBMS2 mRNA
CTD
PMID:34995734
NCBI chr 7:560,787...603,881
Ensembl chr 7:560,648...600,232
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Rbp1
retinol binding protein 1
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of RBP1 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in increased expression of RBP1 protein]
CTD
PMID:28157488
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions decreases expression
ISO EXP
diallyl trisulfide results in decreased phosphorylation of and affects the localization of RELA protein diallyl trisulfide results in decreased expression of RELA mRNA; diallyl trisulfide results in decreased expression of RELA protein diallyl trisulfide inhibits the reaction [Arsenic results in increased expression of RELA protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein]
CTD
PMID:24788927 PMID:25062976 PMID:25927362 PMID:29087013 PMID:30396169
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Reln
reelin
increases expression
ISO
diallyl trisulfide results in increased expression of RELN mRNA
CTD
PMID:34995734
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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Rgmb
repulsive guidance molecule BMP co-receptor b
increases expression
ISO
diallyl trisulfide results in increased expression of RGMB mRNA
CTD
PMID:34995734
NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425
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Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of RHNO1 mRNA
CTD
PMID:34995734
NCBI chr 4:161,634,047...161,639,437
Ensembl chr 4:161,634,048...161,639,371
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Rhoq
ras homolog family member Q
decreases expression
ISO
diallyl trisulfide results in decreased expression of RHOQ mRNA
CTD
PMID:34995734
NCBI chr 6:7,613,632...7,652,047
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Rnase3
ribonuclease A family member 3
increases expression
EXP
diallyl trisulfide results in increased expression of EAR1 mRNA
CTD
PMID:34014027
NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790
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Rnd3
Rho family GTPase 3
increases expression
ISO
diallyl trisulfide results in increased expression of RND3 mRNA
CTD
PMID:34995734
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
increases expression
ISO
diallyl trisulfide results in increased expression of RRAD mRNA
CTD
PMID:34995734
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
ISO
diallyl trisulfide results in decreased expression of RRM2 mRNA
CTD
PMID:34995734
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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Rtel1
regulator of telomere elongation helicase 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of RTEL1 mRNA
CTD
PMID:34995734
NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
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S100a11
S100 calcium binding protein A11
increases expression
ISO
diallyl trisulfide results in increased expression of S100A11 protein
CTD
PMID:16344271
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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S100a6
S100 calcium binding protein A6
increases expression
ISO
diallyl trisulfide results in increased expression of S100A6 mRNA
CTD
PMID:11925593
NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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S1pr1
sphingosine-1-phosphate receptor 1
increases expression
ISO
diallyl trisulfide results in increased expression of S1PR1 mRNA
CTD
PMID:34995734
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
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Samd9
sterile alpha motif domain containing 9
decreases expression
ISO
diallyl trisulfide results in decreased expression of SAMD9 mRNA
CTD
PMID:34995734
NCBI chr 4:31,164,639...31,184,278
Ensembl chr 4:31,164,510...31,184,322
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Sapcd2
suppressor APC domain containing 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of SAPCD2 mRNA
CTD
PMID:34995734
NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
diallyl trisulfide results in increased expression of SAT1 mRNA
CTD
PMID:34995734
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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Scara3
scavenger receptor class A, member 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of SCARA3 mRNA
CTD
PMID:34995734
NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
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Scd
stearoyl-CoA desaturase
decreases expression
EXP
diallyl trisulfide results in decreased expression of SCD mRNA
CTD
PMID:34014027
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Scg5
secretogranin V
increases expression
ISO
diallyl trisulfide results in increased expression of SCG5 mRNA
CTD
PMID:34995734
NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463
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Scube3
signal peptide, CUB domain and EGF like domain containing 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of SCUBE3 mRNA
CTD
PMID:34995734
NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584
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Sdc2
syndecan 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of SDC2 mRNA
CTD
PMID:34995734
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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Sdf2l1
stromal cell-derived factor 2-like 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of SDF2L1 mRNA
CTD
PMID:34995734
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Serpinb2
serpin family B member 2
increases expression
ISO
diallyl trisulfide results in increased expression of SERPINB2 mRNA
CTD
PMID:34995734
NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpine2
serpin family E member 2
increases expression
ISO
diallyl trisulfide results in increased expression of SERPINE2 mRNA
CTD
PMID:11925594
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
ISO
diallyl trisulfide results in increased expression of SGK1 mRNA
CTD
PMID:34995734
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgo2
shugoshin 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of SGO2 mRNA
CTD
PMID:34995734
NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
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Sh2d2a
SH2 domain containing 2A
increases expression
ISO
diallyl trisulfide results in increased expression of SH2D2A mRNA
CTD
PMID:34995734
NCBI chr 2:173,312,253...173,318,810
Ensembl chr 2:173,312,253...173,318,810
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Sh2d5
SH2 domain containing 5
increases expression
ISO
diallyl trisulfide results in increased expression of SH2D5 mRNA
CTD
PMID:34995734
NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955
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Shc1
SHC adaptor protein 1
increases phosphorylation multiple interactions decreases response to substance affects response to substance
ISO
diallyl trisulfide results in increased phosphorylation of SHC1 protein pyrazolanthrone inhibits the reaction [diallyl trisulfide results in increased phosphorylation of SHC1 protein]; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein] SHC1 protein modified form results in decreased susceptibility to diallyl trisulfide SHC1 protein affects the susceptibility to diallyl trisulfide
CTD
PMID:21616139 PMID:22020565
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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Sipa1l2
signal-induced proliferation-associated 1 like 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of SIPA1L2 mRNA
CTD
PMID:34995734
NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428
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Sirt1
sirtuin 1
increases expression
EXP
diallyl trisulfide results in increased expression of SIRT1 mRNA
CTD
PMID:34014027
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Six1
SIX homeobox 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of SIX1 mRNA
CTD
PMID:34995734
NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
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Slc11a1
solute carrier family 11 member 1
increases expression
EXP
diallyl trisulfide results in increased expression of SLC11A1 mRNA
CTD
PMID:34014027
NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
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Slc17a5
solute carrier family 17 member 5
increases expression
ISO
diallyl trisulfide results in increased expression of SLC17A5 mRNA
CTD
PMID:34995734
NCBI chr 8:79,394,416...79,429,387
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Slc25a36
solute carrier family 25 member 36
increases expression
ISO
diallyl trisulfide results in increased expression of SLC25A36 mRNA
CTD
PMID:34995734
NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703
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Slc2a1
solute carrier family 2 member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of SLC2A1 mRNA
CTD
PMID:34995734
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a3
solute carrier family 2 member 3
increases expression
ISO
diallyl trisulfide results in increased expression of SLC2A3 mRNA
CTD
PMID:34995734
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc37a2
solute carrier family 37 member 2
increases expression
ISO
diallyl trisulfide results in increased expression of SLC37A2 mRNA
CTD
PMID:34995734
NCBI chr 8:36,945,787...36,971,748
Ensembl chr 8:36,946,930...36,971,482
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Slc39a1
solute carrier family 39 member 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of SLC39A1 mRNA
CTD
PMID:34995734
NCBI chr 2:175,703,413...175,709,063
Ensembl chr 2:175,703,441...175,709,058
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Slc40a1
solute carrier family 40 member 1
increases expression
EXP
diallyl trisulfide results in increased expression of SLC40A1 mRNA
CTD
PMID:34014027
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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Slc4a1
solute carrier family 4 member 1 (Diego blood group)
increases expression
EXP
diallyl trisulfide results in increased expression of SLC4A1 mRNA
CTD
PMID:34014027
NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
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Slc6a6
solute carrier family 6 member 6
increases expression
ISO
diallyl trisulfide results in increased expression of SLC6A6 mRNA
CTD
PMID:34887701
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slc7a2
solute carrier family 7 member 2
increases expression
ISO
diallyl trisulfide results in increased expression of SLC7A2 mRNA
CTD
PMID:34995734
NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
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Smoc1
SPARC related modular calcium binding 1
increases expression
ISO
diallyl trisulfide results in increased expression of SMOC1 mRNA
CTD
PMID:34995734
NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
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Snai1
snail family transcriptional repressor 1
multiple interactions decreases expression
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein]
CTD
PMID:27566995 PMID:28574600
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snai2
snail family transcriptional repressor 2
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI2 protein]
CTD
PMID:28574600
NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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Snx24
sorting nexin 24
increases expression
ISO
diallyl trisulfide results in increased expression of SNX24 mRNA
CTD
PMID:34995734
NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068
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Sod1
superoxide dismutase 1
increases expression
EXP
diallyl trisulfide results in increased expression of SOD1 protein
CTD
PMID:23453443
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
increases expression multiple interactions
EXP ISO
diallyl trisulfide results in increased expression of SOD2 protein SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] diallyl trisulfide results in increased expression of SOD2 mRNA
CTD
PMID:23412769 PMID:23453443 PMID:34995734
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sox2
SRY-box transcription factor 2
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of SOX2 mRNA; diallyl trisulfide results in decreased expression of SOX2 protein Iodoacetamide inhibits the reaction [diallyl trisulfide results in decreased expression of SOX2 protein]
CTD
PMID:33751676
NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
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Spag5
sperm associated antigen 5
decreases expression
ISO
diallyl trisulfide results in decreased expression of SPAG5 mRNA
CTD
PMID:34995734
NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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Spock2
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
increases expression
EXP
diallyl trisulfide results in increased expression of SPOCK2 mRNA
CTD
PMID:34014027
NCBI chr20:28,037,334...28,064,272
Ensembl chr20:28,033,475...28,064,272
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Spp1
secreted phosphoprotein 1
increases expression
ISO
diallyl trisulfide results in increased expression of SPP1 mRNA
CTD
PMID:34995734
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Spry2
sprouty RTK signaling antagonist 2
increases expression
ISO
diallyl trisulfide results in increased expression of SPRY2 mRNA
CTD
PMID:34995734
NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009
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Sqstm1
sequestosome 1
multiple interactions increases expression
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of SQSTM1 protein] diallyl trisulfide results in increased expression of SQSTM1 mRNA
CTD
PMID:34887701 PMID:34995734 PMID:36796188
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
diallyl trisulfide results in decreased expression of SREBF1 mRNA
CTD
PMID:34014027
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srsf1
serine and arginine rich splicing factor 1
increases expression
ISO
diallyl trisulfide results in increased expression of SRSF1 protein
CTD
PMID:16344271
NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
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Stc1
stanniocalcin 1
increases expression
ISO
diallyl trisulfide results in increased expression of STC1 mRNA
CTD
PMID:34995734
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
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Stil
STIL, centriolar assembly protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of STIL mRNA
CTD
PMID:34995734
NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
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Stra6
signaling receptor and transporter of retinol STRA6
decreases expression
ISO
diallyl trisulfide results in decreased expression of STRA6 mRNA
CTD
PMID:34995734
NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
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Stxbp1
syntaxin binding protein 1
increases expression
ISO
diallyl trisulfide results in increased expression of STXBP1 mRNA
CTD
PMID:34995734
NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
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Suv39h1
SUV39H1 histone lysine methyltransferase
decreases expression
ISO
diallyl trisulfide results in decreased expression of SUV39H1 mRNA
CTD
PMID:34995734
NCBI chr X:14,421,028...14,433,993
Ensembl chr X:14,421,109...14,433,982
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Suv39h1-ps1
SUV39H1 histone lysine methyltransferase, pseudogene 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of SUV39H1 mRNA
CTD
PMID:34995734
NCBI chr X:141,792,589...141,795,257
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Syne2
spectrin repeat containing nuclear envelope protein 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of SYNE2 mRNA
CTD
PMID:34995734
NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064
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Synm
synemin
decreases expression
ISO
diallyl trisulfide results in decreased expression of SYNM mRNA
CTD
PMID:34995734
NCBI chr 1:121,333,712...121,363,652
Ensembl chr 1:121,333,720...121,363,652
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Syt16
synaptotagmin 16
increases expression
ISO
diallyl trisulfide results in increased expression of SYT16 mRNA
CTD
PMID:34995734
NCBI chr 6:92,721,415...92,972,140
Ensembl chr 6:92,721,101...92,971,748
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Tacc3
transforming, acidic coiled-coil containing protein 3
decreases expression
ISO
diallyl trisulfide results in decreased expression of TACC3 mRNA
CTD
PMID:34995734
NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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Tagln2
transgelin 2
increases expression
ISO
diallyl trisulfide results in increased expression of TAGLN2 protein
CTD
PMID:16344271
NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
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Tardbp
TAR DNA binding protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of TARDBP protein
CTD
PMID:30317421
NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
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Tbkbp1
TBK1 binding protein 1
increases expression
ISO
diallyl trisulfide results in increased expression of TBKBP1 mRNA
CTD
PMID:34995734
NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352
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Tbx2
T-box transcription factor 2
increases expression
ISO
diallyl trisulfide results in increased expression of TBX2 mRNA
CTD
PMID:34995734
NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
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Tbxa2r
thromboxane A2 receptor
increases expression
ISO
diallyl trisulfide results in increased expression of TBXA2R mRNA
CTD
PMID:34995734
NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
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Tent5c
terminal nucleotidyltransferase 5C
increases expression
EXP
diallyl trisulfide results in increased expression of FAM46C mRNA
CTD
PMID:34014027
NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
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Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
diallyl trisulfide results in decreased expression of and results in decreased secretion of TGFB1 protein
CTD
PMID:20979868
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
diallyl trisulfide results in increased expression of TIMP1 mRNA; diallyl trisulfide results in increased expression of TIMP1 protein
CTD
PMID:24084732
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression
ISO
diallyl trisulfide results in increased expression of TIMP2 mRNA; diallyl trisulfide results in increased expression of TIMP2 protein
CTD
PMID:24084732
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tk1
thymidine kinase 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of TK1 mRNA
CTD
PMID:34995734
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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Tlr4
toll-like receptor 4
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
CTD
PMID:25500681
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tmem154
transmembrane protein 154
increases expression
ISO
diallyl trisulfide results in increased expression of TMEM154 mRNA
CTD
PMID:34995734
NCBI chr 2:170,015,247...170,054,903
Ensembl chr 2:170,015,184...170,052,481
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Tmem158
transmembrane protein 158
increases expression
ISO
diallyl trisulfide results in increased expression of TMEM158 mRNA
CTD
PMID:34995734
NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673
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Tmem178b
transmembrane protein 178B
decreases expression
ISO
diallyl trisulfide results in decreased expression of TMEM178B mRNA
CTD
PMID:34995734
NCBI chr 4:68,659,425...69,035,690
Ensembl chr 4:68,657,343...69,035,690
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Tmem199
transmembrane protein 199
decreases expression
ISO
diallyl trisulfide results in decreased expression of TMEM199 mRNA
CTD
PMID:34995734
NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108
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Tmem40
transmembrane protein 40
increases expression
ISO
diallyl trisulfide results in increased expression of TMEM40 mRNA
CTD
PMID:34995734
NCBI chr 4:148,791,509...148,819,287
Ensembl chr 4:148,791,505...148,823,665
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Tmem47
transmembrane protein 47
increases expression
ISO
diallyl trisulfide results in increased expression of TMEM47 mRNA
CTD
PMID:34995734
NCBI chr X:45,421,405...45,447,900
Ensembl chr X:45,421,405...45,447,900
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Tmem97
transmembrane protein 97
decreases expression
ISO
diallyl trisulfide results in decreased expression of TMEM97 mRNA
CTD
PMID:34995734
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnf
tumor necrosis factor
decreases secretion decreases expression multiple interactions
ISO EXP
diallyl trisulfide results in decreased secretion of TNF protein diallyl trisulfide results in decreased expression of TNF mRNA [ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] diallyl trisulfide inhibits the reaction [TNF protein affects the localization of JUN protein modified form]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of F3 protein]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of IKBKE mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of MAPK8 mRNA]; diallyl trisulfide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein] diallyl trisulfide inhibits the reaction [Arsenic results in increased expression of TNF protein]
CTD
PMID:16110831 PMID:17448272 PMID:25062976 PMID:25500681 PMID:34848446 PMID:35022635 More...
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
diallyl trisulfide results in increased expression of TNFAIP3 mRNA
CTD
PMID:34995734
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfaip8l1
TNF alpha induced protein 8 like 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of TNFAIP8L1 mRNA
CTD
PMID:34995734
NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254
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Tnfrsf19
TNF receptor superfamily member 19
decreases expression
ISO
diallyl trisulfide results in decreased expression of TNFRSF19 mRNA
CTD
PMID:34995734
NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
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Tnfsf10
TNF superfamily member 10
increases response to substance multiple interactions
ISO
diallyl trisulfide results in increased susceptibility to TNFSF10 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein
CTD
PMID:28571773
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tnfsf9
TNF superfamily member 9
decreases expression
ISO
diallyl trisulfide results in decreased expression of TNFSF9 mRNA
CTD
PMID:34995734
NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
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Top2a
DNA topoisomerase II alpha
decreases expression
ISO
diallyl trisulfide results in decreased expression of TOP2A mRNA
CTD
PMID:34995734
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tp53
tumor protein p53
affects localization increases expression multiple interactions
ISO
diallyl trisulfide affects the localization of TP53 protein diallyl trisulfide results in increased expression of TP53 mRNA; diallyl trisulfide results in increased expression of TP53 protein diallyl trisulfide results in increased expression of and affects the localization of TP53 protein
CTD
PMID:19823037 PMID:23754639 PMID:24415872 PMID:28571773
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpt1
tumor protein, translationally-controlled 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of TPT1 protein
CTD
PMID:16344271
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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Tpx2
TPX2, microtubule nucleation factor
decreases expression
ISO
diallyl trisulfide results in decreased expression of TPX2 mRNA
CTD
PMID:34995734
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Trappc5
trafficking protein particle complex subunit 5
increases expression
ISO
diallyl trisulfide results in increased expression of TRAPPC5 mRNA
CTD
PMID:34995734
NCBI chr12:1,737,666...1,741,312
Ensembl chr12:1,737,627...1,742,637
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Trib2
tribbles pseudokinase 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of TRIB2 mRNA
CTD
PMID:34995734
NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370
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Trim58
tripartite motif-containing 58
increases expression
ISO
diallyl trisulfide results in increased expression of TRIM58 mRNA
CTD
PMID:34995734
NCBI chr10:43,022,933...43,038,984
Ensembl chr10:43,022,996...43,034,476
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Trim62
tripartite motif-containing 62
decreases expression
ISO
diallyl trisulfide results in decreased expression of TRIM62 mRNA
CTD
PMID:34995734
NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915
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Troap
trophinin associated protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of TROAP mRNA
CTD
PMID:34995734
NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
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Tshr
thyroid stimulating hormone receptor
increases expression
ISO
diallyl trisulfide results in increased expression of TSHR protein
CTD
PMID:33751676
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Tsku
tsukushi, small leucine rich proteoglycan
increases expression
EXP
diallyl trisulfide results in increased expression of TSKU mRNA
CTD
PMID:34014027
NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
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Ttk
Ttk protein kinase
decreases expression
ISO
diallyl trisulfide results in decreased expression of TTK mRNA
CTD
PMID:34995734
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Tuba1b
tubulin, alpha 1B
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBA1B mRNA
CTD
PMID:34995734
NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
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Tuba1c
tubulin, alpha 1C
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBA1C mRNA
CTD
PMID:34995734
NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647 Ensembl chr X:130,192,016...130,199,647
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Tuba3b
tubulin, alpha 3B
increases expression
EXP
diallyl trisulfide results in increased expression of TUBA3B mRNA
CTD
PMID:34014027
NCBI chr 4:178,588,779...178,594,328
Ensembl chr 4:178,588,779...178,594,326
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Tuba4a
tubulin, alpha 4A
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBA4A mRNA
CTD
PMID:34995734
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Tubb2a
tubulin, beta 2A class IIa
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBB2A mRNA
CTD
PMID:34995734
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Tubb3
tubulin, beta 3 class III
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBB3 mRNA
CTD
PMID:34995734
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Tubb4b
tubulin, beta 4B class IVb
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBB4B mRNA
CTD
PMID:34995734
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Tubg1
tubulin, gamma 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of TUBG1 mRNA
CTD
PMID:34995734
NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433
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Twist1
twist family bHLH transcription factor 1
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of TWIST1 protein LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]
CTD
PMID:27566995
NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Txn1
thioredoxin 1
decreases expression multiple interactions decreases reduction
ISO
diallyl trisulfide results in decreased expression of TXN protein TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein] diallyl trisulfide results in decreased reduction of TXN protein
CTD
PMID:28574600 PMID:30396169
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnip
thioredoxin interacting protein
increases expression multiple interactions
ISO
diallyl trisulfide results in increased expression of TXNIP protein TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein]
CTD
PMID:30396169
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Tyms
thymidylate synthetase
decreases expression
ISO
diallyl trisulfide results in decreased expression of TYMS mRNA
CTD
PMID:34995734
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Ube2c
ubiquitin-conjugating enzyme E2C
decreases expression
ISO
diallyl trisulfide results in decreased expression of UBE2C mRNA
CTD
PMID:34995734
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Ubfd1
ubiquitin family domain containing 1
increases expression
ISO
diallyl trisulfide results in increased expression of UBFD1 mRNA
CTD
PMID:34995734
NCBI chr 1:176,626,003...176,640,993
Ensembl chr 1:176,625,657...176,640,993
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Uchl1
ubiquitin C-terminal hydrolase L1
decreases expression increases expression
ISO EXP
diallyl trisulfide results in decreased expression of UCHL1 protein diallyl trisulfide results in increased expression of UCHL1 mRNA
CTD
PMID:19550292 PMID:34014027
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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Ugcg
UDP-glucose ceramide glucosyltransferase
increases expression
ISO
diallyl trisulfide results in increased expression of UGCG mRNA
CTD
PMID:34995734
NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases expression
EXP
diallyl trisulfide results in increased expression of UGT1A1 mRNA
CTD
PMID:20650352
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Usp53
ubiquitin specific peptidase 53
increases expression
ISO
diallyl trisulfide results in increased expression of USP53 mRNA
CTD
PMID:34995734
NCBI chr 2:211,059,512...211,120,942
Ensembl chr 2:211,059,520...211,120,943
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Ust
uronyl-2-sulfotransferase
increases expression
ISO
diallyl trisulfide results in increased expression of UST mRNA
CTD
PMID:34995734
NCBI chr 1:2,666,983...2,962,276
Ensembl chr 1:2,669,592...2,962,044
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Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO
diallyl trisulfide inhibits the reaction [VCAM1 protein results in increased expression of F3 mRNA]
CTD
PMID:35022635
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vcan
versican
decreases expression
ISO
diallyl trisulfide results in decreased expression of VCAN mRNA
CTD
PMID:34995734
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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Vdac1
voltage-dependent anion channel 1
decreases expression
ISO
diallyl trisulfide results in decreased expression of VDAC1 protein
CTD
PMID:16344271
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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Vdac2
voltage-dependent anion channel 2
decreases expression
ISO
diallyl trisulfide results in decreased expression of VDAC2 protein
CTD
PMID:16344271
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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Vdr
vitamin D receptor
decreases expression
ISO
diallyl trisulfide results in decreased expression of VDR mRNA
CTD
PMID:34995734
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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Vegfa
vascular endothelial growth factor A
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of VEGFA mRNA; diallyl trisulfide results in decreased expression of VEGFA protein diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; diallyl trisulfide results in decreased expression of and results in decreased secretion of VEGFA protein; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]
CTD
PMID:23430952 PMID:23754639 PMID:28574600
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vim
vimentin
decreases expression multiple interactions
ISO
diallyl trisulfide results in decreased expression of VIM protein SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]
CTD
PMID:19550292 PMID:23412769
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vps9d1
VPS9 domain containing 1
increases expression
ISO
diallyl trisulfide results in increased expression of VPS9D1 mRNA
CTD
PMID:34995734
NCBI chr19:51,276,998...51,290,726
Ensembl chr19:51,277,000...51,290,634
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Vsir
V-set immunoregulatory receptor
decreases expression
ISO
diallyl trisulfide results in decreased expression of VSIR mRNA
CTD
PMID:34995734
NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
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Wdr37
WD repeat domain 37
increases expression
ISO
diallyl trisulfide results in increased expression of WDR37 mRNA
CTD
PMID:34995734
NCBI chr17:61,637,258...61,703,677
Ensembl chr17:61,637,258...61,703,677
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Wdr62
WD repeat domain 62
decreases expression
ISO
diallyl trisulfide results in decreased expression of WDR62 mRNA
CTD
PMID:34995734
NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637
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Wt1
WT1 transcription factor
increases expression
EXP
diallyl trisulfide results in increased expression of WT1 mRNA
CTD
PMID:34014027
NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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Xdh
xanthine dehydrogenase
multiple interactions increases expression
ISO
diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of and results in increased activity of XDH protein] diallyl trisulfide results in increased expression of XDH mRNA
CTD
PMID:34995734 PMID:36796188
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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Xiap
X-linked inhibitor of apoptosis
increases degradation decreases expression multiple interactions decreases response to substance
ISO
diallyl trisulfide results in increased degradation of XIAP protein diallyl trisulfide results in decreased expression of XIAP mRNA; diallyl trisulfide results in decreased expression of XIAP protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein] XIAP protein results in decreased susceptibility to diallyl trisulfide
CTD
PMID:21411500 PMID:22578287 PMID:25205294 PMID:34995734
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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Yy1
YY1 transcription factor
multiple interactions
EXP
[diallyl trisulfide co-treated with cypermethrin] results in decreased expression of YY1 protein
CTD
PMID:34794910
NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
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Zdhhc12
zinc finger DHHC-type palmitoyltransferase 12
increases expression
ISO
diallyl trisulfide results in increased expression of ZDHHC12 mRNA
CTD
PMID:34995734
NCBI chr 3:13,363,504...13,366,383
Ensembl chr 3:13,363,504...13,366,474
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Zfp239
zinc finger protein 239
increases expression
ISO
diallyl trisulfide results in increased expression of ZNF239 mRNA
CTD
PMID:34995734
NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529
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Zfp580
zinc finger protein 580
increases expression
ISO
diallyl trisulfide results in increased expression of ZNF580 mRNA
CTD
PMID:34995734
NCBI chr 1:68,787,118...68,789,286
Ensembl chr 1:68,787,118...68,789,286
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Zfp672
zinc finger protein 672
increases expression
ISO
diallyl trisulfide results in increased expression of ZNF672 mRNA
CTD
PMID:34995734
NCBI chr10:42,496,558...42,512,134
Ensembl chr10:42,495,476...42,504,852
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Zwint
ZW10 interacting kinetochore protein
decreases expression
ISO
diallyl trisulfide results in decreased expression of ZWINT mRNA
CTD
PMID:34995734
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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