Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:food anticaking agent
go back to main search page
Accession:CHEBI:77965 term browser browse the term
Definition:An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
Synonyms:related_synonym: food anti-caking agent;   food anti-caking agents


show annotations for term's descendants           Sort by:
calcium silicate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP calcium silicate results in increased expression of ADIPOQ mRNA CTD PMID:29279043 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Alb albumin increases expression EXP calcium silicate results in increased expression of ALB mRNA CTD PMID:29279043 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions EXP [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor increases expression EXP calcium silicate results in increased expression of AMBP mRNA CTD PMID:29279043 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036 		JBrowse link
G Ankrd39 ankyrin repeat domain 39 increases expression EXP calcium silicate results in increased expression of ANKRD39 mRNA CTD PMID:29279043 NCBI chr 1:36,577,252...36,586,333
Ensembl chr 1:36,576,588...36,586,526 		JBrowse link
G Aoah acyloxyacyl hydrolase increases expression EXP calcium silicate results in increased expression of AOAH mRNA CTD PMID:29279043 NCBI chr13:20,978,273...21,220,787
Ensembl chr13:20,978,283...21,220,787 		JBrowse link
G Apoa2 apolipoprotein A-II increases expression EXP calcium silicate results in increased expression of APOA2 mRNA CTD PMID:29279043 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apob apolipoprotein B increases expression EXP calcium silicate results in increased expression of APOB mRNA CTD PMID:29279043 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression EXP calcium silicate results in decreased expression of ARMCX2 mRNA CTD PMID:29279043 NCBI chr  X:133,704,891...133,709,970
Ensembl chr  X:133,704,894...133,709,970 		JBrowse link
G Aste1 asteroid homolog 1 increases expression EXP calcium silicate results in increased expression of ASTE1 mRNA CTD PMID:29279043 NCBI chr 9:105,272,533...105,285,497
Ensembl chr 9:105,272,591...105,289,428 		JBrowse link
G Bcl9l B cell CLL/lymphoma 9-like decreases expression EXP calcium silicate results in decreased expression of BCL9L mRNA CTD PMID:29279043 NCBI chr 9:44,394,103...44,423,203
Ensembl chr 9:44,394,122...44,423,193 		JBrowse link
G Bgn biglycan decreases expression EXP calcium silicate results in decreased expression of BGN mRNA CTD PMID:29279043 NCBI chr  X:72,527,207...72,539,542
Ensembl chr  X:72,527,208...72,539,539 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression EXP calcium silicate results in increased expression of BMAL1 mRNA CTD PMID:29279043 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression EXP calcium silicate results in decreased expression of BPTF mRNA CTD PMID:29279043 NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953 		JBrowse link
G Capns1 calpain, small subunit 1 decreases expression EXP calcium silicate results in decreased expression of CAPNS1 mRNA CTD PMID:29279043 NCBI chr 7:29,886,359...29,898,308
Ensembl chr 7:29,886,361...29,898,236 		JBrowse link
G Car3 carbonic anhydrase 3 increases expression EXP calcium silicate results in increased expression of CAR3 mRNA CTD PMID:29279043 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO calcium silicate results in increased expression of CCL2 protein CTD PMID:16601788 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO calcium silicate results in increased expression of CCL3 protein CTD PMID:16601788 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ces1a carboxylesterase 1A increases expression EXP calcium silicate results in increased expression of CES1A mRNA CTD PMID:29279043 NCBI chr 8:93,746,842...93,774,820
Ensembl chr 8:93,746,842...93,774,820 		JBrowse link
G Chrnb3 cholinergic receptor, nicotinic, beta polypeptide 3 increases expression EXP calcium silicate results in increased expression of CHRNB3 mRNA CTD PMID:29279043 NCBI chr 8:27,858,688...27,889,758
Ensembl chr 8:27,858,739...27,889,758 		JBrowse link
G Clca1 chloride channel accessory 1 increases expression EXP calcium silicate results in increased expression of CLCA1 mRNA CTD PMID:29279043 NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537 		JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP [Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA CTD PMID:23483914 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases secretion		 ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of CXCL8 protein] CTD PMID:21762757 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide increases expression EXP calcium silicate results in increased expression of CYBB mRNA CTD PMID:29279043 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B increases expression EXP calcium silicate results in increased expression of CYP3A41B mRNA CTD PMID:29279043 NCBI chr 5:145,495,474...145,521,542
Ensembl chr 5:145,495,474...145,521,540 		JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 increases expression EXP calcium silicate results in increased expression of CYP3A44 mRNA CTD PMID:29279043 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684 		JBrowse link
G Ddo D-aspartate oxidase decreases expression EXP calcium silicate results in decreased expression of DDO mRNA CTD PMID:29279043 NCBI chr10:40,505,933...40,557,847
Ensembl chr10:40,506,007...40,557,843 		JBrowse link
G Defa29 defensin, alpha, 29 increases expression EXP calcium silicate results in increased expression of DEFA29 mRNA CTD PMID:29279043 NCBI chr 8:21,815,904...21,817,034
Ensembl chr 8:21,815,903...21,817,036 		JBrowse link
G Defb45 defensin beta 45 increases expression EXP calcium silicate results in increased expression of DEFB45 mRNA CTD PMID:29279043 NCBI chr 2:152,435,111...152,438,405
Ensembl chr 2:152,435,111...152,441,319 		JBrowse link
G Dhx35 DEAH-box helicase 35 increases expression EXP calcium silicate results in increased expression of DHX35 mRNA CTD PMID:29279043 NCBI chr 2:158,636,674...158,700,141
Ensembl chr 2:158,636,727...158,700,134 		JBrowse link
G Dpp10 dipeptidylpeptidase 10 increases expression EXP calcium silicate results in increased expression of DPP10 mRNA CTD PMID:29279043 NCBI chr 1:123,259,871...124,773,774
Ensembl chr 1:123,249,200...124,773,776 		JBrowse link
G Egfr epidermal growth factor receptor increases activity ISO calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 increases expression EXP calcium silicate results in increased expression of EPB42 mRNA CTD PMID:29279043 NCBI chr 2:120,848,372...120,867,358
Ensembl chr 2:120,848,372...120,867,553 		JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression EXP calcium silicate results in increased expression of FAM83H mRNA CTD PMID:29279043 NCBI chr15:75,872,941...75,886,185
Ensembl chr15:75,872,942...75,886,185 		JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP calcium silicate results in increased expression of FGG mRNA CTD PMID:29279043 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Fgl1 fibrinogen-like protein 1 increases expression EXP calcium silicate results in increased expression of FGL1 mRNA CTD PMID:29279043 NCBI chr 8:41,644,471...41,671,015
Ensembl chr 8:41,644,471...41,668,193 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 increases secretion
multiple interactions		 ISO calcium silicate results in increased secretion of FLT1 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of FLT1 protein]		 CTD PMID:21762757 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Gc vitamin D binding protein increases expression EXP calcium silicate results in increased expression of GC mRNA CTD PMID:29279043 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 increases expression EXP calcium silicate results in increased expression of GLT8D1 mRNA CTD PMID:29279043 NCBI chr14:30,723,137...30,733,948
Ensembl chr14:30,723,357...30,733,948 		JBrowse link
G Gsr glutathione reductase increases activity ISO calcium silicate results in increased activity of GSR protein CTD PMID:16601788 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression EXP calcium silicate results in decreased expression of H1F2 mRNA CTD PMID:29279043 NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350 		JBrowse link
G H3c8 H3 clustered histone 8 increases expression EXP calcium silicate results in increased expression of H3C8 mRNA CTD PMID:29279043 NCBI chr13:23,719,588...23,720,079
Ensembl chr13:23,719,592...23,720,121 		JBrowse link
G Hlf hepatic leukemia factor decreases expression EXP calcium silicate results in decreased expression of HLF mRNA CTD PMID:29279043 NCBI chr11:90,227,361...90,281,745
Ensembl chr11:90,227,362...90,281,721 		JBrowse link
G Hmg20b high mobility group 20B decreases expression EXP calcium silicate results in decreased expression of HMG20B mRNA CTD PMID:29279043 NCBI chr10:81,181,880...81,186,777
Ensembl chr10:81,181,882...81,186,314 		JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression EXP calcium silicate results in increased expression of HPCAL1 mRNA CTD PMID:29279043 NCBI chr12:17,740,810...17,841,943
Ensembl chr12:17,740,857...17,841,934 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igh-VJ558 immunoglobulin heavy chain (J558 family) increases expression EXP calcium silicate results in increased expression of IGH-VJ558 mRNA CTD PMID:29279043
G Ighg3 Immunoglobulin heavy constant gamma 3 increases expression EXP calcium silicate results in increased expression of IGHG3 mRNA CTD PMID:29279043 NCBI chr12:113,321,062...113,324,852
Ensembl chr12:113,319,844...113,324,852 		JBrowse link
G Ighm immunoglobulin heavy constant mu increases expression EXP calcium silicate results in increased expression of IGHM mRNA CTD PMID:29279043 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion		 ISO Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [calcium silicate results in increased secretion of IL6 protein] CTD PMID:21762757 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression EXP calcium silicate results in decreased expression of IPMK mRNA CTD PMID:29279043 NCBI chr10:71,183,574...71,221,715
Ensembl chr10:71,183,593...71,269,157 		JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 decreases expression EXP calcium silicate results in decreased expression of KANK4 mRNA CTD PMID:29279043 NCBI chr 4:98,643,129...98,706,295
Ensembl chr 4:98,643,135...98,705,774 		JBrowse link
G Kat8 K(lysine) acetyltransferase 8 increases expression EXP calcium silicate results in increased expression of KAT8 mRNA CTD PMID:29279043 NCBI chr 7:127,511,689...127,525,010
Ensembl chr 7:127,511,688...127,525,009 		JBrowse link
G Kcnmb4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 decreases expression EXP calcium silicate results in decreased expression of KCNMB4 mRNA CTD PMID:29279043 NCBI chr10:116,251,951...116,309,787
Ensembl chr10:116,253,766...116,309,783 		JBrowse link
G Kdr kinase insert domain protein receptor increases secretion ISO calcium silicate results in increased secretion of KDR protein CTD PMID:21762757 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Klhl2 kelch-like 2, Mayven decreases expression EXP calcium silicate results in decreased expression of KLHL2 mRNA CTD PMID:29279043 NCBI chr 8:65,192,707...65,302,821
Ensembl chr 8:65,192,709...65,302,669 		JBrowse link
G Ldb1 LIM domain binding 1 decreases expression EXP calcium silicate results in decreased expression of LDB1 mRNA CTD PMID:29279043 NCBI chr19:46,019,963...46,036,584
Ensembl chr19:46,020,009...46,033,653 		JBrowse link
G Lmo7 LIM domain only 7 decreases expression EXP calcium silicate results in decreased expression of LMO7 mRNA CTD PMID:29279043 NCBI chr14:101,967,353...102,172,144
Ensembl chr14:101,967,386...102,172,146 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression EXP calcium silicate results in decreased expression of LTN1 mRNA CTD PMID:29279043 NCBI chr16:87,173,539...87,229,504
Ensembl chr16:87,173,539...87,229,500 		JBrowse link
G Malt1 MALT1 paracaspase increases expression EXP calcium silicate results in increased expression of MALT1 mRNA CTD PMID:29279043 NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO calcium silicate results in increased phosphorylation of MAPK1 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK1 protein]		 CTD PMID:21762757 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO calcium silicate results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK3 protein]		 CTD PMID:21762757 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression EXP calcium silicate results in increased expression of MATK mRNA CTD PMID:29279043 NCBI chr10:81,088,769...81,098,819
Ensembl chr10:81,088,769...81,099,199 		JBrowse link
G Mettl8 methyltransferase 8, methylcytidine increases expression EXP calcium silicate results in increased expression of METTL8 mRNA CTD PMID:29279043 NCBI chr 2:70,794,902...70,886,729
Ensembl chr 2:70,794,905...70,885,927 		JBrowse link
G Mfsd11 major facilitator superfamily domain containing 11 decreases expression EXP calcium silicate results in decreased expression of MFSD11 mRNA CTD PMID:29279043 NCBI chr11:116,743,037...116,766,486
Ensembl chr11:116,743,266...116,766,461 		JBrowse link
G Mup1 major urinary protein 1 increases expression EXP calcium silicate results in increased expression of MUP1 mRNA CTD PMID:29279043 NCBI chr 4:60,454,011...60,457,959
Ensembl chr 4:60,454,011...60,457,959 		JBrowse link
G Mup10 major urinary protein 10 increases expression EXP calcium silicate results in increased expression of MUP10 mRNA CTD PMID:29279043 NCBI chr 4:60,534,259...60,538,275
Ensembl chr 4:60,534,259...60,538,198 		JBrowse link
G Mup11 major urinary protein 11 increases expression EXP calcium silicate results in increased expression of MUP11 mRNA CTD PMID:29279043 NCBI chr 4:60,614,465...60,618,438
Ensembl chr 4:60,614,465...60,618,410 		JBrowse link
G Mup18 major urinary protein 18 increases expression EXP calcium silicate results in increased expression of MUP18 mRNA CTD PMID:29279043 NCBI chr 4:61,588,414...61,592,389
Ensembl chr 4:61,588,414...61,592,373 		JBrowse link
G Mup5 major urinary protein 5 increases expression EXP calcium silicate results in increased expression of MUP5 mRNA CTD PMID:29279043 NCBI chr 4:61,749,556...61,753,417
Ensembl chr 4:61,749,556...61,753,470 		JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression EXP calcium silicate results in increased expression of NAA38 mRNA CTD PMID:29279043 NCBI chr11:69,286,617...69,287,497
Ensembl chr11:69,286,313...69,287,506 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase decreases expression EXP calcium silicate results in decreased expression of NANP mRNA CTD PMID:29279043 NCBI chr 2:150,871,605...150,881,299
Ensembl chr 2:150,871,605...150,881,318 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression EXP calcium silicate results in increased expression of NOP53 mRNA CTD PMID:29279043 NCBI chr 7:15,671,760...15,680,033
Ensembl chr 7:15,670,108...15,679,999 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP calcium silicate results in decreased expression of NR1D1 mRNA CTD PMID:29279043 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression EXP calcium silicate results in decreased expression of NR1D2 mRNA CTD PMID:29279043 NCBI chr14:4,230,549...4,265,639
Ensembl chr14:4,230,569...4,265,642 		JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 increases expression EXP calcium silicate results in increased expression of NTRK3 mRNA CTD PMID:29279043 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760 		JBrowse link
G Oaf out at first homolog increases expression EXP calcium silicate results in increased expression of OAF mRNA CTD PMID:29279043 NCBI chr 9:43,132,575...43,151,113
Ensembl chr 9:43,132,532...43,151,208 		JBrowse link
G Oas1b 2'-5' oligoadenylate synthetase 1B increases expression EXP calcium silicate results in increased expression of OAS1B mRNA CTD PMID:29279043 NCBI chr 5:120,950,700...120,962,228
Ensembl chr 5:120,950,700...120,962,228 		JBrowse link
G Ormdl2 ORM1-like 2 (S. cerevisiae) increases expression EXP calcium silicate results in increased expression of ORMDL2 mRNA CTD PMID:29279043 NCBI chr10:128,653,771...128,657,498
Ensembl chr10:128,653,771...128,657,514 		JBrowse link
G Osbpl3 oxysterol binding protein-like 3 increases expression EXP calcium silicate results in increased expression of OSBPL3 mRNA CTD PMID:29279043 NCBI chr 6:50,270,307...50,433,334
Ensembl chr 6:50,270,310...50,433,181 		JBrowse link
G P4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide decreases expression EXP calcium silicate results in decreased expression of P4HA2 mRNA CTD PMID:29279043 NCBI chr11:53,991,750...54,022,494
Ensembl chr11:53,990,921...54,022,491 		JBrowse link
G Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 decreases expression EXP calcium silicate results in decreased expression of PAG1 mRNA CTD PMID:29279043 NCBI chr 3:9,752,539...9,898,744
Ensembl chr 3:9,752,539...9,898,739 		JBrowse link
G Pantr2 POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2 increases expression EXP calcium silicate results in increased expression of PANTR2 mRNA CTD PMID:29279043 NCBI chr 1:42,746,221...42,752,614
Ensembl chr 1:42,687,360...42,752,940 		JBrowse link
G Per3 period circadian clock 3 decreases expression EXP calcium silicate results in decreased expression of PER3 mRNA CTD PMID:29279043 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression EXP calcium silicate results in decreased expression of PFKFB3 mRNA CTD PMID:29279043 NCBI chr 2:11,476,241...11,558,882
Ensembl chr 2:11,476,244...11,558,888 		JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase increases expression EXP calcium silicate results in increased expression of PHGDH mRNA CTD PMID:29279043 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma increases expression EXP calcium silicate results in increased expression of PIK3CG mRNA CTD PMID:29279043 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Plaa phospholipase A2, activating protein increases expression EXP calcium silicate results in increased expression of PLAA mRNA CTD PMID:29279043 NCBI chr 4:94,453,371...94,491,410
Ensembl chr 4:94,455,751...94,491,481 		JBrowse link
G Pmm2 phosphomannomutase 2 increases expression EXP calcium silicate results in increased expression of PMM2 mRNA CTD PMID:29279043 NCBI chr16:8,455,467...8,475,472
Ensembl chr16:8,455,538...8,480,331 		JBrowse link
G Prl3b1 prolactin family 3, subfamily b, member 1 increases expression EXP calcium silicate results in increased expression of PRL3B1 mRNA CTD PMID:29279043 NCBI chr13:27,426,413...27,433,666
Ensembl chr13:27,425,830...27,433,666 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 decreases expression EXP calcium silicate results in decreased expression of PRPF19 mRNA CTD PMID:29279043 NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases localization ISO calcium silicate results in increased localization of RELA protein CTD PMID:21762757 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP calcium silicate results in increased expression of RHOBTB2 mRNA CTD PMID:29279043 NCBI chr14:70,022,439...70,062,296
Ensembl chr14:70,022,439...70,043,085 		JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase decreases expression EXP calcium silicate results in decreased expression of RNMT mRNA CTD PMID:29279043 NCBI chr18:68,433,406...68,457,923
Ensembl chr18:68,433,426...68,457,923 		JBrowse link
G Rps25 ribosomal protein S25 decreases expression EXP calcium silicate results in decreased expression of RPS25 mRNA CTD PMID:29279043 NCBI chr 9:44,319,011...44,321,703
Ensembl chr 9:44,318,436...44,321,724 		JBrowse link
G Rwdd3 RWD domain containing 3 increases expression EXP calcium silicate results in increased expression of RWDD3 mRNA CTD PMID:29279043 NCBI chr 3:120,949,046...120,965,427
Ensembl chr 3:120,949,047...120,965,344 		JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 increases expression EXP calcium silicate results in increased expression of SCGB3A1 mRNA CTD PMID:29279043 NCBI chr11:49,554,422...49,555,945
Ensembl chr11:49,554,437...49,555,945 		JBrowse link
G Schip1 schwannomin interacting protein 1 decreases expression EXP calcium silicate results in decreased expression of SCHIP1 mRNA CTD PMID:29279043 NCBI chr 3:67,972,135...68,533,815
Ensembl chr 3:67,972,135...68,533,814 		JBrowse link
G Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A increases expression EXP calcium silicate results in increased expression of SERPINA1A mRNA CTD PMID:29279043 NCBI chr12:103,819,554...103,829,878
Ensembl chr12:103,819,848...103,829,821 		JBrowse link
G Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B increases expression EXP calcium silicate results in increased expression of SERPINA1B mRNA CTD PMID:29279043 NCBI chr12:103,694,415...103,704,448
Ensembl chr12:103,694,415...103,796,632 		JBrowse link
G Serpina1e serine (or cysteine) peptidase inhibitor, clade A, member 1E increases expression EXP calcium silicate results in increased expression of SERPINA1E mRNA CTD PMID:29279043 NCBI chr12:103,913,190...103,923,156
Ensembl chr12:103,913,190...103,925,234 		JBrowse link
G Serpinb6c serine (or cysteine) peptidase inhibitor, clade B, member 6c increases expression EXP calcium silicate results in increased expression of SERPINB6C mRNA CTD PMID:29279043 NCBI chr13:34,063,799...34,089,709
Ensembl chr13:34,063,799...34,089,691 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression EXP calcium silicate results in decreased expression of SGMS1 mRNA CTD PMID:29279043 NCBI chr19:32,100,127...32,367,285
Ensembl chr19:32,100,127...32,367,114 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 decreases expression EXP calcium silicate results in decreased expression of SLC1A5 mRNA CTD PMID:29279043 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Slc38a10 solute carrier family 38, member 10 decreases expression EXP calcium silicate results in decreased expression of SLC38A10 mRNA CTD PMID:29279043 NCBI chr11:119,994,777...120,042,177
Ensembl chr11:119,994,786...120,042,172 		JBrowse link
G Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 increases expression EXP calcium silicate results in increased expression of SLC6A13 mRNA CTD PMID:29279043 NCBI chr 6:121,277,247...121,314,680
Ensembl chr 6:121,277,186...121,314,692 		JBrowse link
G Snord61 small nucleolar RNA, C/D box 61 decreases expression EXP calcium silicate results in decreased expression of SNORD61 mRNA CTD PMID:29279043 NCBI chr  X:56,436,808...56,436,869
Ensembl chr  X:56,436,809...56,436,879 		JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases activity ISO calcium silicate results in decreased activity of SOD1 protein CTD PMID:16601788 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Ssbp3 single-stranded DNA binding protein 3 decreases expression EXP calcium silicate results in decreased expression of SSBP3 mRNA CTD PMID:29279043 NCBI chr 4:106,768,667...106,906,891
Ensembl chr 4:106,767,898...106,906,891 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression EXP calcium silicate results in increased expression of TAF10 mRNA CTD PMID:29279043 NCBI chr 7:105,392,101...105,393,550
Ensembl chr 7:105,388,600...105,393,568 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Zinc binds to calcium silicate] which results in increased expression of TGFB1 mRNA CTD PMID:23483914 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Them7 thioesterase superfamily member 7 increases expression EXP calcium silicate results in increased expression of THEM7 mRNA CTD PMID:29279043 NCBI chr 2:105,054,687...105,210,205
Ensembl chr 2:105,054,665...105,210,141 		JBrowse link
G Tmem171 transmembrane protein 171 increases expression EXP calcium silicate results in increased expression of TMEM171 mRNA CTD PMID:29279043 NCBI chr13:98,822,744...98,832,142
Ensembl chr13:98,822,743...98,831,342 		JBrowse link
G Tmem54 transmembrane protein 54 increases expression EXP calcium silicate results in increased expression of TMEM54 mRNA CTD PMID:29279043 NCBI chr 4:128,999,321...129,005,419
Ensembl chr 4:128,999,341...129,005,419 		JBrowse link
G Tmod4 tropomodulin 4 increases expression EXP calcium silicate results in increased expression of TMOD4 mRNA CTD PMID:29279043 NCBI chr 3:95,030,110...95,036,520
Ensembl chr 3:95,031,787...95,036,520 		JBrowse link
G Trp53 transformation related protein 53 increases expression EXP calcium silicate results in increased expression of TRP53 mRNA CTD PMID:29279043 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP calcium silicate results in decreased expression of TUBA1C mRNA CTD PMID:29279043 NCBI chr15:98,927,772...98,935,986
Ensembl chr15:98,927,772...98,935,991 		JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion
multiple interactions		 ISO calcium silicate results in increased secretion of VEGFA protein
RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of VEGFA protein]		 CTD PMID:21762757 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vmn2r24 vomeronasal 2, receptor 24 increases expression EXP calcium silicate results in increased expression of VMN2R24 mRNA CTD PMID:29279043 NCBI chr 6:123,755,930...123,793,239
Ensembl chr 6:123,755,838...123,801,871 		JBrowse link
G Vps35l VPS35 endosomal protein sorting factor like increases expression EXP calcium silicate results in increased expression of VPS35L mRNA CTD PMID:29279043 NCBI chr 7:118,339,401...118,440,712
Ensembl chr 7:118,339,449...118,442,189 		JBrowse link
G Xlr5c X-linked lymphocyte-regulated 5C increases expression EXP calcium silicate results in increased expression of XLR5C mRNA CTD PMID:29279043 NCBI chr  X:72,326,967...72,337,469
Ensembl chr  X:72,326,502...72,336,582 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A decreases expression EXP calcium silicate results in decreased expression of ZC3H12A mRNA CTD PMID:29279043 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression EXP calcium silicate results in increased expression of ZMYND8 mRNA CTD PMID:29279043 NCBI chr 2:165,626,072...165,740,896
Ensembl chr 2:165,626,072...165,740,936 		JBrowse link
D-mannitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA] CTD PMID:15327746 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta decreases expression EXP Mannitol results in decreased expression of ACACB mRNA CTD PMID:25270620 NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822 		JBrowse link
G Acly ATP citrate lyase increases expression EXP Mannitol results in increased expression of ACLY mRNA CTD PMID:25270620 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826 		JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif 18 increases expression EXP Mannitol results in increased expression of ADAMTS18 mRNA CTD PMID:25270620 NCBI chr 8:114,423,755...114,575,975
Ensembl chr 8:114,423,758...114,575,370 		JBrowse link
G Aida axin interactor, dorsalization associated decreases expression EXP Mannitol results in decreased expression of AIDA mRNA CTD PMID:25270620 NCBI chr 1:183,078,604...183,105,356
Ensembl chr 1:183,078,134...183,106,331 		JBrowse link
G Aire autoimmune regulator decreases expression EXP Mannitol results in decreased expression of AIRE mRNA CTD PMID:25270620 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Aqp9 aquaporin 9 increases uptake ISO AQP9 protein results in increased uptake of Mannitol CTD PMID:9733774 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Mannitol results in increased expression of ARHGAP1 mRNA CTD PMID:25270620 NCBI chr 2:91,480,463...91,502,670
Ensembl chr 2:91,480,205...91,502,671 		JBrowse link
G Arr3 arrestin 3, retinal increases expression EXP Mannitol results in increased expression of ARR3 mRNA CTD PMID:25270620 NCBI chr  X:99,649,086...99,662,099
Ensembl chr  X:99,649,103...99,662,099 		JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation
multiple interactions		 ISO Mannitol results in increased phosphorylation of BAD protein
wortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]		 CTD PMID:15786717 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein] CTD PMID:29803612 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP Mannitol results in decreased expression of BBOX1 mRNA CTD PMID:25270620 NCBI chr 2:110,094,401...110,145,158
Ensembl chr 2:110,093,042...110,144,905 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Mannitol results in increased expression of BCL2 protein CTD PMID:15786717 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Cables2 CDK5 and Abl enzyme substrate 2 decreases expression EXP Mannitol results in decreased expression of CABLES2 mRNA CTD PMID:25270620 NCBI chr 2:179,900,332...179,915,258
Ensembl chr 2:179,900,333...179,915,289 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein] CTD PMID:10567913 PMID:12011046 PMID:29803612 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 increases activity ISO Mannitol results in increased activity of CASP9 protein CTD PMID:12011046 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cbx1 chromobox 1 increases expression EXP Mannitol results in increased expression of CBX1 mRNA CTD PMID:25270620 NCBI chr11:96,679,506...96,699,808
Ensembl chr11:96,679,953...96,699,466 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression EXP Mannitol results in decreased expression of CCDC127 mRNA CTD PMID:25270620 NCBI chr13:74,498,436...74,513,902
Ensembl chr13:74,498,428...74,513,902 		JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression EXP Mannitol results in decreased expression of CCN3 mRNA CTD PMID:25270620 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression EXP Mannitol results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 2:91,357,092...91,451,024
Ensembl chr 2:91,357,107...91,451,009 		JBrowse link
G Clcn3 chloride channel, voltage-sensitive 3 affects response to substance ISO CLCN3 protein affects the susceptibility to Mannitol deficiency CTD PMID:22108225 NCBI chr 8:61,363,423...61,436,351
Ensembl chr 8:61,363,423...61,436,334 		JBrowse link
G Ctnna2 catenin alpha 2 decreases expression EXP Mannitol results in decreased expression of CTNNA2 mRNA CTD PMID:25270620 NCBI chr 6:76,858,620...77,956,798
Ensembl chr 6:76,858,620...77,956,682 		JBrowse link
G Cyp2j6 cytochrome P450, family 2, subfamily j, polypeptide 6 decreases expression EXP Mannitol results in decreased expression of CYP2J6 mRNA CTD PMID:25270620 NCBI chr 4:96,404,375...96,449,835
Ensembl chr 4:96,404,375...96,441,898 		JBrowse link
G Dbh dopamine beta hydroxylase increases expression EXP Mannitol results in increased expression of DBH mRNA CTD PMID:25270620 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212 		JBrowse link
G Dctn2 dynactin 2 increases expression EXP Mannitol results in increased expression of DCTN2 mRNA CTD PMID:25270620 NCBI chr10:127,102,131...127,117,828
Ensembl chr10:127,102,237...127,117,819 		JBrowse link
G Defb7 defensin beta 7 decreases expression EXP Mannitol results in decreased expression of DEFB7 mRNA CTD PMID:25270620 NCBI chr 8:19,545,113...19,547,791
Ensembl chr 8:19,545,113...19,547,791 		JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression EXP Mannitol results in increased expression of DGKA mRNA CTD PMID:25270620 NCBI chr10:128,556,000...128,581,002
Ensembl chr10:128,556,003...128,580,724 		JBrowse link
G Drr1 developmentally regulated repeat element-containing transcript 1 increases expression EXP Mannitol results in increased expression of DRR1 mRNA CTD PMID:25270620 Ensembl chr  X:15,788,543...15,805,488 JBrowse link
G Elf2 E74-like factor 2 increases expression EXP Mannitol results in increased expression of ELF2 mRNA CTD PMID:25270620 NCBI chr 3:51,160,141...51,248,101
Ensembl chr 3:51,160,141...51,248,084 		JBrowse link
G Fam185a family with sequence similarity 185, member A increases expression EXP Mannitol results in increased expression of FAM185A mRNA CTD PMID:25270620 NCBI chr 5:21,629,861...21,693,269
Ensembl chr 5:21,629,956...21,687,122 		JBrowse link
G Fam222a family with sequence similarity 222, member A decreases expression EXP Mannitol results in decreased expression of FAM222A mRNA CTD PMID:25270620 NCBI chr 5:114,706,312...114,751,281
Ensembl chr 5:114,706,077...114,751,281 		JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression
multiple interactions
decreases export		 EXP
ISO		 Mannitol results in decreased expression of FGF23 mRNA
Mannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 mRNA]; Mannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 protein]
Mannitol results in decreased export of FGF23 protein		 CTD PMID:37992803 NCBI chr 6:127,049,865...127,059,257
Ensembl chr 6:127,049,865...127,058,371 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Mannitol results in increased expression of FOS mRNA CTD PMID:11557636 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gal3st2 galactose-3-O-sulfotransferase 2 decreases expression EXP Mannitol results in decreased expression of GAL3ST2 mRNA CTD PMID:25270620 NCBI chr 1:93,789,066...93,804,220
Ensembl chr 1:93,789,028...93,804,216 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 decreases expression EXP Mannitol results in decreased expression of GAS2L2 mRNA CTD PMID:25270620 NCBI chr11:83,312,461...83,320,347
Ensembl chr11:83,312,728...83,320,281 		JBrowse link
G Gpc6 glypican 6 increases expression EXP Mannitol results in increased expression of GPC6 mRNA CTD PMID:25270620 NCBI chr14:117,162,332...118,216,941
Ensembl chr14:117,162,727...118,213,956 		JBrowse link
G Gpr19 G protein-coupled receptor 19 decreases expression EXP Mannitol results in decreased expression of GPR19 mRNA CTD PMID:25270620 NCBI chr 6:134,846,055...134,875,157
Ensembl chr 6:134,846,056...134,875,541 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Mannitol results in increased expression of HMOX1 mRNA CTD PMID:11592956 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP Mannitol results in increased expression of HPRT1 mRNA CTD PMID:25270620 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Hrh2 histamine receptor H2 increases expression EXP Mannitol results in increased expression of HRH2 mRNA CTD PMID:25270620 NCBI chr13:54,345,990...54,390,201
Ensembl chr13:54,346,148...54,390,199 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 protein] CTD PMID:16285992 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein] CTD PMID:10567913 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Rotenone inhibits the reaction [Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] CTD PMID:23867654 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Jun jun proto-oncogene increases expression ISO Mannitol results in increased expression of JUN mRNA CTD PMID:11557636 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member increases expression EXP Mannitol results in increased expression of KHDC3 mRNA CTD PMID:25270620 NCBI chr 9:73,008,660...73,013,915
Ensembl chr 9:73,009,118...73,011,720 		JBrowse link
G Krtap11-1 keratin associated protein 11-1 increases expression EXP Mannitol results in increased expression of KRTAP11-1 mRNA CTD PMID:25270620 NCBI chr16:89,367,064...89,368,071
Ensembl chr16:89,367,064...89,368,071 		JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP Mannitol results in decreased expression of LSM6 mRNA CTD PMID:25270620 NCBI chr 8:79,531,497...79,547,781
Ensembl chr 8:79,531,494...79,547,769 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK1 protein] CTD PMID:10910949 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mta2 metastasis-associated gene family, member 2 increases expression EXP Mannitol results in increased expression of MTA2 mRNA CTD PMID:25270620 NCBI chr19:8,919,239...8,929,659
Ensembl chr19:8,919,239...8,929,667 		JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory decreases phosphorylation ISO Mannitol results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578 		JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression EXP Mannitol results in increased expression of MYLK3 mRNA CTD PMID:25270620 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 increases expression EXP Mannitol results in increased expression of NAALAD2 mRNA CTD PMID:25270620 NCBI chr 9:18,233,247...18,308,834
Ensembl chr 9:18,233,247...18,314,291 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 decreases expression EXP Mannitol results in decreased expression of NDUFA13 mRNA CTD PMID:25270620 NCBI chr 8:70,346,813...70,355,208
Ensembl chr 8:70,346,830...70,355,208 		JBrowse link
G Nfat5 nuclear factor of activated T cells 5 increases expression
multiple interactions		 EXP
ISO		 Mannitol results in increased expression of NFAT5 mRNA
Mannitol inhibits the reaction [Sodium Chloride deficiency results in decreased expression of NFAT5 mRNA]
Mannitol results in increased expression of NFAT5 mRNA; Mannitol results in increased expression of NFAT5 protein		 CTD PMID:23867654 PMID:37992803 NCBI chr 8:108,020,072...108,106,149
Ensembl chr 8:108,020,102...108,106,149 		JBrowse link
G Ngp neutrophilic granule protein decreases expression EXP Mannitol results in decreased expression of NGP mRNA CTD PMID:25270620 NCBI chr 9:110,248,876...110,252,080
Ensembl chr 9:110,248,815...110,252,080 		JBrowse link
G Nkg7 natural killer cell group 7 sequence increases expression EXP Mannitol results in increased expression of NKG7 mRNA CTD PMID:25270620 NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673 		JBrowse link
G Nppa natriuretic peptide type A increases expression ISO Mannitol results in increased expression of NPPA protein CTD PMID:2177369 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nts neurotensin increases transport ISO NTS protein results in increased transport of Mannitol CTD PMID:11208724 NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127 		JBrowse link
G Pcp2 Purkinje cell protein 2 (L7) increases expression EXP Mannitol results in increased expression of PCP2 mRNA CTD PMID:25270620 NCBI chr 8:3,673,369...3,675,547
Ensembl chr 8:3,673,371...3,675,545 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression
decreases expression		 ISO Mannitol results in increased expression of PDCD4 mRNA
Mannitol results in decreased expression of PDCD4 mRNA		 CTD PMID:21873647 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291 		JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO Mannitol results in increased expression of PHEX mRNA CTD PMID:37992803 NCBI chr  X:155,945,071...156,198,282
Ensembl chr  X:155,945,071...156,198,308 		JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression EXP Mannitol results in decreased expression of PLCL2 mRNA CTD PMID:25270620 NCBI chr17:50,815,893...50,995,522
Ensembl chr17:50,816,431...50,995,512 		JBrowse link
G Plekho1 pleckstrin homology domain containing, family O member 1 increases expression EXP Mannitol results in increased expression of PLEKHO1 mRNA CTD PMID:25270620 NCBI chr 3:95,896,110...95,903,258
Ensembl chr 3:95,895,741...95,903,313 		JBrowse link
G Pou1f1 POU domain, class 1, transcription factor 1 increases expression EXP Mannitol results in increased expression of POU1F1 mRNA CTD PMID:25270620 NCBI chr16:65,317,398...65,331,904
Ensembl chr16:65,317,397...65,331,183 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression EXP Mannitol results in decreased expression of PPP1R10 mRNA CTD PMID:25270620 NCBI chr17:36,227,404...36,243,175
Ensembl chr17:36,227,326...36,243,175 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit increases expression EXP Mannitol results in increased expression of PPP4C mRNA CTD PMID:25270620 NCBI chr 7:126,385,038...126,391,729
Ensembl chr 7:126,385,038...126,391,668 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCD protein] CTD PMID:16285992 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167 		JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) increases expression ISO Mannitol results in increased expression of PTGER1 mRNA CTD PMID:12888618 NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) decreases expression ISO Mannitol results in decreased expression of PTGER4 mRNA CTD PMID:12888618 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein]; Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein CTD PMID:12011046 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression EXP Mannitol results in decreased expression of RBL1 mRNA CTD PMID:25270620 NCBI chr 2:156,987,813...157,046,454
Ensembl chr 2:156,987,813...157,046,454 		JBrowse link
G Rbp2 retinol binding protein 2, cellular decreases expression EXP Mannitol results in decreased expression of RBP2 mRNA CTD PMID:25270620 NCBI chr 9:98,372,590...98,391,824
Ensembl chr 9:98,368,168...98,391,834 		JBrowse link
G Rgl3 ral guanine nucleotide dissociation stimulator-like 3 increases expression EXP Mannitol results in increased expression of RGL3 mRNA CTD PMID:25270620 NCBI chr 9:21,882,475...21,900,765
Ensembl chr 9:21,880,007...21,900,742 		JBrowse link
G Samd10 sterile alpha motif domain containing 10 decreases expression EXP Mannitol results in decreased expression of SAMD10 mRNA CTD PMID:25270620 NCBI chr 2:181,237,008...181,241,227
Ensembl chr 2:181,237,011...181,241,005 		JBrowse link
G Sbsn suprabasin decreases expression EXP Mannitol results in decreased expression of SBSN mRNA CTD PMID:25270620 NCBI chr 7:30,432,099...30,455,559
Ensembl chr 7:30,450,896...30,455,559 		JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein] CTD PMID:16285992 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Sgsm3 small G protein signaling modulator 3 decreases expression EXP Mannitol results in decreased expression of SGSM3 mRNA CTD PMID:25270620 NCBI chr15:80,861,966...80,896,491
Ensembl chr15:80,861,966...80,896,491 		JBrowse link
G Slc12a1 solute carrier family 12, member 1 increases activity
multiple interactions		 ISO Mannitol results in increased activity of SLC12A1 protein
[Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water		 CTD PMID:12433675 NCBI chr 2:124,994,430...125,071,922
Ensembl chr 2:124,994,425...125,071,922 		JBrowse link
G Slc2a8 solute carrier family 2, (facilitated glucose transporter), member 8 decreases expression EXP Mannitol results in decreased expression of SLC2A8 mRNA CTD PMID:25270620 NCBI chr 2:32,862,993...32,872,088
Ensembl chr 2:32,863,002...32,872,095 		JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Stx8 syntaxin 8 decreases expression EXP Mannitol results in decreased expression of STX8 mRNA CTD PMID:25270620 NCBI chr11:67,857,237...68,097,974
Ensembl chr11:67,857,019...68,097,974 		JBrowse link
G Timd4 T cell immunoglobulin and mucin domain containing 4 decreases expression EXP Mannitol results in decreased expression of TIMD4 mRNA CTD PMID:25270620 NCBI chr11:46,701,613...46,735,160
Ensembl chr11:46,701,627...46,735,159 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein] CTD PMID:19298665 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 increases expression ISO Mannitol results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression		 ISO Mannitol results in decreased expression of TPD52 mRNA
Mannitol results in increased expression of TPD52 mRNA		 CTD PMID:21873647 NCBI chr 3:8,991,590...9,069,824
Ensembl chr 3:8,990,653...9,069,783 		JBrowse link
G Triml1 tripartite motif family-like 1 increases expression EXP Mannitol results in increased expression of TRIML1 mRNA CTD PMID:25270620 NCBI chr 8:43,582,843...43,633,531
Ensembl chr 8:43,582,844...43,594,523 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ulbp1 UL16 binding protein 1 increases expression EXP Mannitol results in increased expression of ULBP1 mRNA CTD PMID:25270620 NCBI chr10:7,394,873...7,423,643
Ensembl chr10:7,390,362...7,423,638 		JBrowse link
G Usmg2 upregulated during skeletal muscle growth 2 decreases expression EXP Mannitol results in decreased expression of USMG2 mRNA CTD PMID:25270620
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 protein] CTD PMID:16285992 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Wdr20 WD repeat domain 20 decreases expression EXP Mannitol results in decreased expression of WDR20 mRNA CTD PMID:25270620 NCBI chr12:110,701,459...110,770,709
Ensembl chr12:110,704,378...110,770,672 		JBrowse link
G Zfp13 zinc finger protein 13 decreases expression EXP Mannitol results in decreased expression of ZFP13 mRNA CTD PMID:25270620 NCBI chr17:23,788,820...23,818,729
Ensembl chr17:23,794,818...23,818,461 		JBrowse link
G Zg16 zymogen granule protein 16 decreases expression EXP Mannitol results in decreased expression of ZG16 mRNA CTD PMID:25270620 NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500 		JBrowse link
G Zim1 zinc finger, imprinted 1 increases expression EXP Mannitol results in increased expression of ZIM1 mRNA CTD PMID:25270620 NCBI chr 7:6,677,443...6,699,521
Ensembl chr 7:6,674,268...6,699,449 		JBrowse link
sodium hydrogencarbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression ISO Sodium Bicarbonate results in increased expression of ABCC2 mRNA CTD PMID:29126803 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) decreases expression ISO Sodium Bicarbonate results in decreased expression of ABCG2 mRNA CTD PMID:29126803 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression ISO Sodium Bicarbonate results in decreased expression of CAR2 mRNA CTD PMID:31569818 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Cat catalase multiple interactions EXP [Folic Acid co-treated with Sodium Bicarbonate] results in decreased activity of CAT protein CTD PMID:25559736 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of FN1 protein] CTD PMID:10430982 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Sodium Bicarbonate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064 		JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 multiple interactions EXP [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] CTD PMID:25559736 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA] CTD PMID:25559736 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 decreases expression ISO Sodium Bicarbonate results in decreased expression of SLC15A1 mRNA CTD PMID:29126803 NCBI chr14:121,697,033...121,742,666
Ensembl chr14:121,697,033...121,742,664 		JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 increases expression ISO Sodium Bicarbonate results in increased expression of SLC22A24 mRNA CTD PMID:29126803 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675 		JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 decreases expression ISO Sodium Bicarbonate results in decreased expression of SLC22A6 mRNA CTD PMID:29126803 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663 		JBrowse link
G Slc39a8 solute carrier family 39 (metal ion transporter), member 8 multiple interactions ISO SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of Cadmium Chloride]; SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of manganese chloride] CTD PMID:21509381 NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333 		JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 decreases expression ISO Sodium Bicarbonate results in decreased expression of SLC4A1 mRNA CTD PMID:31569818 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029 		JBrowse link
G Slc4a4 solute carrier family 4 (anion exchanger), member 4 increases transport
decreases expression		 ISO SLC4A4 protein results in increased transport of Sodium Bicarbonate
Sodium Bicarbonate results in decreased expression of SLC4A4 mRNA		 CTD PMID:18614622 PMID:31569818 NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of TGFB1 mRNA] CTD PMID:10430982 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA] CTD PMID:25559736 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA] CTD PMID:25559736 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Vim vimentin multiple interactions ISO Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of VIM protein] CTD PMID:10430982 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22276
    role 22261
      application 21884
        food additive 18179
          food anticaking agent 232
            D-mannitol + 99
            calcium silicate 123
            dimethicone polymer 0
            potassium bitartrate 0
            sodium hydrogencarbonate 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 22276
    role 22261
      biological role 22260
        physiological role 22253
          food component 22253
            food additive 18179
              food anticaking agent 232
                D-mannitol + 99
                calcium silicate 123
                dimethicone polymer 0
                potassium bitartrate 0
                sodium hydrogencarbonate 18
paths to the root