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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:anticaking agent
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Accession:CHEBI:77964 term browser browse the term
Definition:A substance added to powdered or granulated materials in order to prevent the formation of lumps and so facilitate its packaging or transport.
Synonyms:related_synonym: anti-caking agent;   anti-caking agents;   anticaking agents
 xref: Wikipedia:Anti-caking_agent


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calcium silicate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO calcium silicate results in increased expression of ADIPOQ mRNA CTD PMID:29279043 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Alb albumin increases expression ISO calcium silicate results in increased expression of ALB mRNA CTD PMID:29279043 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO calcium silicate results in increased expression of AMBP mRNA CTD PMID:29279043 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:81,583,622...81,593,850 		JBrowse link
G Ankrd39 ankyrin repeat domain 39 increases expression ISO calcium silicate results in increased expression of ANKRD39 mRNA CTD PMID:29279043 NCBI chr 9:38,780,291...38,790,177
Ensembl chr 9:46,279,952...46,286,043 		JBrowse link
G Aoah acyloxyacyl hydrolase increases expression ISO calcium silicate results in increased expression of AOAH mRNA CTD PMID:29279043 NCBI chr17:48,503,812...48,745,161
Ensembl chr17:48,503,812...48,745,146 		JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO calcium silicate results in increased expression of APOA2 mRNA CTD PMID:29279043 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Apob apolipoprotein B increases expression ISO calcium silicate results in increased expression of APOB mRNA CTD PMID:29279043 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression ISO calcium silicate results in decreased expression of ARMCX2 mRNA CTD PMID:29279043 NCBI chr  X:102,273,915...102,278,789
Ensembl chr  X:102,273,565...102,278,905 		JBrowse link
G Aste1 asteroid homolog 1 increases expression ISO calcium silicate results in increased expression of ASTE1 mRNA CTD PMID:29279043 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:114,905,266...114,923,105 		JBrowse link
G Bcl9l BCL9 like decreases expression ISO calcium silicate results in decreased expression of BCL9L mRNA CTD PMID:29279043 NCBI chr 8:53,708,770...53,738,880
Ensembl chr 8:53,708,770...53,737,395 		JBrowse link
G Bgn biglycan decreases expression ISO calcium silicate results in decreased expression of BGN mRNA CTD PMID:29279043 NCBI chr  X:156,348,633...156,360,797
Ensembl chr  X:156,348,615...156,360,799 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO calcium silicate results in increased expression of BMAL1 mRNA CTD PMID:29279043 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO calcium silicate results in decreased expression of BPTF mRNA CTD PMID:29279043 NCBI chr10:92,480,007...92,582,485
Ensembl chr10:92,480,007...92,582,413 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO calcium silicate results in increased expression of CAR3 mRNA CTD PMID:29279043 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO calcium silicate results in decreased expression of CAPNS1 mRNA CTD PMID:29279043 NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:94,572,083...94,583,368 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP calcium silicate results in increased expression of CCL2 protein CTD PMID:16601788 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression EXP calcium silicate results in increased expression of CCL3 protein CTD PMID:16601788 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO calcium silicate results in decreased expression of CCND1 protein CTD PMID:38301883 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO calcium silicate results in increased expression of CHRNB3 mRNA CTD PMID:29279043 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225 		JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO calcium silicate results in increased expression of CLCA1 mRNA CTD PMID:29279043 NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA CTD PMID:23483914 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO calcium silicate results in increased expression of CYBB mRNA CTD PMID:29279043 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO calcium silicate results in decreased expression of DDO mRNA CTD PMID:29279043 NCBI chr20:45,673,486...45,693,056
Ensembl chr20:45,675,532...45,715,758 		JBrowse link
G Dhx35 DEAH-box helicase 35 increases expression ISO calcium silicate results in increased expression of DHX35 mRNA CTD PMID:29279043 NCBI chr 3:167,869,971...167,927,300
Ensembl chr 3:167,870,055...167,927,300 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 increases expression ISO calcium silicate results in increased expression of DPP10 mRNA CTD PMID:29279043 NCBI chr13:34,584,420...36,269,292
Ensembl chr13:37,145,531...38,822,801 		JBrowse link
G Egfr epidermal growth factor receptor increases activity ISO calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 increases expression ISO calcium silicate results in increased expression of EPB42 mRNA CTD PMID:29279043 NCBI chr 3:128,433,460...128,451,683
Ensembl chr 3:128,433,464...128,451,683 		JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO calcium silicate results in increased expression of FAM83H mRNA CTD PMID:29279043 NCBI chr 7:109,597,129...109,605,317
Ensembl chr 7:109,597,129...109,609,188 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO calcium silicate results in increased expression of FGG mRNA CTD PMID:29279043 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO calcium silicate results in increased expression of FGL1 mRNA CTD PMID:29279043 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:57,824,200...57,854,429 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases secretion 		ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of FLT1 protein] CTD PMID:21762757 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Gc GC, vitamin D binding protein increases expression ISO calcium silicate results in increased expression of GC mRNA CTD PMID:29279043 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673 		JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 increases expression ISO calcium silicate results in increased expression of GLT8D1 mRNA CTD PMID:29279043 NCBI chr16:6,198,152...6,213,671
Ensembl chr16:6,204,740...6,213,668 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP calcium silicate results in increased activity of GSR protein CTD PMID:16601788 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO calcium silicate results in decreased expression of H1F2 mRNA CTD PMID:29279043 NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO calcium silicate results in decreased expression of H2AX protein CTD PMID:38301883 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO calcium silicate results in decreased expression of HLF mRNA CTD PMID:29279043 NCBI chr10:75,651,320...75,708,979
Ensembl chr10:75,654,534...75,708,619 		JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO calcium silicate results in decreased expression of HMG20B mRNA CTD PMID:29279043 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:9,019,698...9,024,377 		JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO calcium silicate results in increased expression of HPCAL1 mRNA CTD PMID:29279043 NCBI chr 6:46,206,809...46,313,364
Ensembl chr 6:46,260,494...46,313,353 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion 		ISO Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [calcium silicate results in increased secretion of IL6 protein] CTD PMID:21762757 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression ISO calcium silicate results in decreased expression of IPMK mRNA CTD PMID:29279043 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,216,151...17,250,757 		JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 decreases expression ISO calcium silicate results in decreased expression of KANK4 mRNA CTD PMID:29279043 NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:118,517,971...118,581,002 		JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO calcium silicate results in increased expression of KAT8 mRNA CTD PMID:29279043 NCBI chr 1:191,954,827...191,967,107
Ensembl chr 1:191,954,438...191,967,105 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 decreases expression ISO calcium silicate results in decreased expression of KCNMB4 mRNA CTD PMID:29279043 NCBI chr 7:53,952,150...54,005,101
Ensembl chr 7:53,949,881...54,005,281 		JBrowse link
G Kdr kinase insert domain receptor increases secretion ISO calcium silicate results in increased secretion of KDR protein CTD PMID:21762757 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Klhl2 kelch-like family member 2 decreases expression ISO calcium silicate results in decreased expression of KLHL2 mRNA CTD PMID:29279043 NCBI chr16:29,627,171...29,739,782
Ensembl chr16:29,627,237...29,739,957 		JBrowse link
G Ldb1 LIM domain binding 1 decreases expression ISO calcium silicate results in decreased expression of LDB1 mRNA CTD PMID:29279043 NCBI chr 1:254,813,161...254,838,931
Ensembl chr 1:254,826,160...254,838,998 		JBrowse link
G Lmo7 LIM domain 7 decreases expression ISO calcium silicate results in decreased expression of LMO7 mRNA CTD PMID:29279043 NCBI chr15:84,981,689...85,184,554
Ensembl chr15:84,981,735...85,184,551 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO calcium silicate results in decreased expression of LTN1 mRNA CTD PMID:29279043 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:40,090,169...40,147,303 		JBrowse link
G Malt1 MALT1 paracaspase increases expression ISO calcium silicate results in increased expression of MALT1 mRNA CTD PMID:29279043 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:61,212,317...61,266,272 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK1 protein] CTD PMID:21762757 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions 		ISO calcium silicate results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK3 protein] 		CTD PMID:21762757 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression ISO calcium silicate results in increased expression of MATK mRNA CTD PMID:29279043 NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:9,107,722...9,112,746 		JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine increases expression ISO calcium silicate results in increased expression of METTL8 mRNA CTD PMID:29279043 NCBI chr 3:76,140,465...76,271,367
Ensembl chr 3:76,144,178...76,271,400 		JBrowse link
G Mfsd11 major facilitator superfamily domain containing 11 decreases expression ISO calcium silicate results in decreased expression of MFSD11 mRNA CTD PMID:29279043 NCBI chr10:102,055,516...102,075,064
Ensembl chr10:102,555,050...102,573,439 		JBrowse link
G Mup18 major urinary protein 18 increases expression ISO calcium silicate results in increased expression of MUP18 mRNA CTD PMID:29279043 NCBI chr 5:74,986,813...74,990,071 JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression ISO calcium silicate results in increased expression of NAA38 mRNA CTD PMID:29279043 NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase decreases expression ISO calcium silicate results in decreased expression of NANP mRNA CTD PMID:29279043 NCBI chr 3:160,289,269...160,302,001
Ensembl chr 3:160,288,830...160,302,002 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO calcium silicate results in increased expression of NOP53 mRNA CTD PMID:29279043 NCBI chr 1:85,757,271...85,765,089
Ensembl chr 1:85,756,586...85,765,089 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO calcium silicate results in decreased expression of NR1D1 mRNA CTD PMID:29279043 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression ISO calcium silicate results in decreased expression of NR1D2 mRNA CTD PMID:29279043 NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO calcium silicate results in increased expression of NTRK3 mRNA CTD PMID:29279043 NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004 		JBrowse link
G Oaf out at first homolog increases expression ISO calcium silicate results in increased expression of OAF mRNA CTD PMID:29279043 NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 increases expression ISO calcium silicate results in increased expression of ORMDL2 mRNA CTD PMID:29279043 NCBI chr 7:1,832,368...1,835,501
Ensembl chr 7:1,832,368...1,836,223 		JBrowse link
G Osbpl3 oxysterol binding protein-like 3 increases expression ISO calcium silicate results in increased expression of OSBPL3 mRNA CTD PMID:29279043 NCBI chr 4:80,677,383...80,854,169
Ensembl chr 4:80,677,390...80,854,169 		JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO calcium silicate results in decreased expression of P4HA2 mRNA CTD PMID:29279043 NCBI chr10:38,743,894...38,772,741
Ensembl chr10:38,743,894...38,772,993 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO calcium silicate results in decreased expression of PAG1 mRNA CTD PMID:29279043 NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO calcium silicate results in decreased expression of PCNA protein CTD PMID:38301883 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Per3 period circadian regulator 3 decreases expression ISO calcium silicate results in decreased expression of PER3 mRNA CTD PMID:29279043 NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO calcium silicate results in decreased expression of PFKFB3 mRNA CTD PMID:29279043 NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO calcium silicate results in increased expression of PHGDH mRNA CTD PMID:29279043 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma increases expression ISO calcium silicate results in increased expression of PIK3CG mRNA CTD PMID:29279043 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509 		JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO calcium silicate results in increased expression of PLAA mRNA CTD PMID:29279043 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:114,544,325...114,576,109 		JBrowse link
G Pmm2 phosphomannomutase 2 increases expression ISO calcium silicate results in increased expression of PMM2 mRNA CTD PMID:29279043 NCBI chr10:7,468,371...7,489,574
Ensembl chr10:7,468,372...7,489,554 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 decreases expression ISO calcium silicate results in decreased expression of PRPF19 mRNA CTD PMID:29279043 NCBI chr 1:216,966,104...216,977,549
Ensembl chr 1:216,966,462...216,980,506 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO calcium silicate results in increased localization of RELA protein CTD PMID:21762757 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression ISO calcium silicate results in increased expression of RHOBTB2 mRNA CTD PMID:29279043 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:51,280,149...51,298,209 		JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase decreases expression ISO calcium silicate results in decreased expression of RNMT mRNA CTD PMID:29279043 NCBI chr18:64,156,067...64,179,601
Ensembl chr18:64,156,154...64,179,500 		JBrowse link
G Rps25 ribosomal protein s25 decreases expression ISO calcium silicate results in decreased expression of RPS25 mRNA CTD PMID:29279043 NCBI chr 8:53,630,333...53,632,810
Ensembl chr 8:53,629,861...53,632,808
Ensembl chr 8:53,629,861...53,632,808 		JBrowse link
G Rwdd3 RWD domain containing 3 increases expression ISO calcium silicate results in increased expression of RWDD3 mRNA CTD PMID:29279043 NCBI chr 2:209,233,622...209,254,842
Ensembl chr 2:211,918,361...211,933,592 		JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 increases expression ISO calcium silicate results in increased expression of SCGB3A1 mRNA CTD PMID:29279043 NCBI chr10:33,968,059...33,969,366
Ensembl chr10:34,468,002...34,470,583 		JBrowse link
G Schip1 schwannomin interacting protein 1 decreases expression ISO calcium silicate results in decreased expression of SCHIP1 mRNA CTD PMID:29279043 NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:155,060,798...155,198,557 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO calcium silicate results in decreased expression of SGMS1 mRNA CTD PMID:29279043 NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO calcium silicate results in decreased expression of SLC1A5 mRNA CTD PMID:29279043 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054 		JBrowse link
G Slc38a10 solute carrier family 38, member 10 decreases expression ISO calcium silicate results in decreased expression of SLC38A10 mRNA CTD PMID:29279043 NCBI chr10:105,885,250...105,935,043
Ensembl chr10:105,885,250...105,935,043 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 increases expression ISO calcium silicate results in increased expression of SLC6A13 mRNA CTD PMID:29279043 NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:156,211,462...156,248,489 		JBrowse link
G Snord61 small nucleolar RNA, C/D box 61 decreases expression ISO calcium silicate results in decreased expression of SNORD61 mRNA CTD PMID:29279043 NCBI chr  X:135,313,247...135,313,319
Ensembl chr  X:140,350,552...140,350,624 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP calcium silicate results in decreased activity of SOD1 protein CTD PMID:16601788 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Ssbp3 single stranded DNA binding protein 3 decreases expression ISO calcium silicate results in decreased expression of SSBP3 mRNA CTD PMID:29279043 NCBI chr 5:126,920,145...127,057,968
Ensembl chr 5:126,919,120...127,056,799 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression ISO calcium silicate results in increased expression of TAF10 mRNA CTD PMID:29279043 NCBI chr 1:169,506,940...169,508,234
Ensembl chr 1:169,506,940...169,508,208 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of TGFB1 mRNA CTD PMID:23483914 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Them7 thioesterase superfamily member 7 increases expression ISO calcium silicate results in increased expression of THEM7 mRNA CTD PMID:29279043 NCBI chr 3:91,666,144...91,834,783
Ensembl chr 3:112,120,937...112,289,569 		JBrowse link
G Tmem171 transmembrane protein 171 increases expression ISO calcium silicate results in increased expression of TMEM171 mRNA CTD PMID:29279043 NCBI chr 2:31,769,486...31,779,358
Ensembl chr 2:31,769,486...31,780,134 		JBrowse link
G Tmem54 transmembrane protein 54 increases expression ISO calcium silicate results in increased expression of TMEM54 mRNA CTD PMID:29279043 NCBI chr 5:141,449,191...141,455,683
Ensembl chr 5:146,733,511...146,740,047 		JBrowse link
G Tmod4 tropomodulin 4 increases expression ISO calcium silicate results in increased expression of TMOD4 mRNA CTD PMID:29279043 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:185,384,795...185,389,992 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO calcium silicate results in increased expression of TRP53 mRNA CTD PMID:29279043 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO calcium silicate results in decreased expression of TUBA1C mRNA CTD PMID:29279043 NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion 		ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of VEGFA protein] CTD PMID:21762757 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vps35l VPS35 endosomal protein sorting factor like increases expression ISO calcium silicate results in increased expression of VPS35L mRNA CTD PMID:29279043 NCBI chr 1:173,076,219...173,179,663
Ensembl chr 1:182,507,266...182,613,087 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A decreases expression ISO calcium silicate results in decreased expression of ZC3H12A mRNA CTD PMID:29279043 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression ISO calcium silicate results in increased expression of ZMYND8 mRNA CTD PMID:29279043 NCBI chr 3:174,948,162...175,061,382
Ensembl chr 3:174,948,537...175,061,571 		JBrowse link
D-mannitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA] CTD PMID:15327746 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO Mannitol results in decreased expression of ACACB mRNA CTD PMID:25270620 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G Acly ATP citrate lyase increases expression ISO Mannitol results in increased expression of ACLY mRNA CTD PMID:25270620 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 increases expression ISO Mannitol results in increased expression of ADAMTS18 mRNA CTD PMID:25270620 NCBI chr19:58,596,095...58,749,239
Ensembl chr19:58,597,761...58,749,138 		JBrowse link
G Aida axin interactor, dorsalization associated decreases expression ISO Mannitol results in decreased expression of AIDA mRNA CTD PMID:25270620 NCBI chr13:97,471,931...97,499,531
Ensembl chr13:97,471,604...97,499,535 		JBrowse link
G Aire autoimmune regulator decreases expression ISO Mannitol results in decreased expression of AIRE mRNA CTD PMID:25270620 NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,635,775...10,650,709 		JBrowse link
G Aqp9 aquaporin 9 increases uptake EXP AQP9 protein results in increased uptake of Mannitol CTD PMID:9733774 NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression ISO Mannitol results in increased expression of ARHGAP1 mRNA CTD PMID:25270620 NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154 		JBrowse link
G Arr3 arrestin 3 increases expression ISO Mannitol results in increased expression of ARR3 mRNA CTD PMID:25270620 NCBI chr  X:69,739,959...69,752,300
Ensembl chr  X:69,739,760...69,752,200 		JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation
multiple interactions 		EXP Mannitol results in increased phosphorylation of BAD protein
wortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein] 		CTD PMID:15786717 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein] CTD PMID:29803612 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO Mannitol results in decreased expression of BBOX1 mRNA CTD PMID:25270620 NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Mannitol results in increased expression of BCL2 protein CTD PMID:15786717 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Mannitol results in decreased expression of CABLES2 mRNA CTD PMID:25270620 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:187,725,031...187,740,027 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity 		ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein] CTD PMID:10567913 PMID:12011046 PMID:29803612 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases activity ISO Mannitol results in increased activity of CASP9 protein CTD PMID:12011046 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cbx1 chromobox 1 increases expression ISO Mannitol results in increased expression of CBX1 mRNA CTD PMID:25270620 NCBI chr10:82,266,746...82,286,431
Ensembl chr10:82,266,759...82,287,242 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO Mannitol results in decreased expression of CCDC127 mRNA CTD PMID:25270620 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:30,757,010...30,764,473 		JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression ISO Mannitol results in decreased expression of CCN3 mRNA CTD PMID:25270620 NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO Mannitol results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 affects response to substance ISO CLCN3 protein affects the susceptibility to Mannitol deficiency CTD PMID:22108225 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Ctnna2 catenin alpha 2 decreases expression ISO Mannitol results in decreased expression of CTNNA2 mRNA CTD PMID:25270620 NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365 		JBrowse link
G Dbh dopamine beta-hydroxylase increases expression ISO Mannitol results in increased expression of DBH mRNA CTD PMID:25270620 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Dctn2 dynactin subunit 2 increases expression ISO Mannitol results in increased expression of DCTN2 mRNA CTD PMID:25270620 NCBI chr 7:64,977,338...64,992,875
Ensembl chr 7:64,977,363...64,992,873 		JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Mannitol results in increased expression of DGKA mRNA CTD PMID:25270620 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,733,248...1,759,569 		JBrowse link
G Elf2 E74 like ETS transcription factor 2 increases expression ISO Mannitol results in increased expression of ELF2 mRNA CTD PMID:25270620 NCBI chr 2:137,445,787...137,536,512
Ensembl chr 2:137,445,788...137,470,355 		JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression ISO Mannitol results in increased expression of DRR1 mRNA CTD PMID:25270620 NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219 		JBrowse link
G Fam185a family with sequence similarity 185, member A increases expression ISO Mannitol results in increased expression of FAM185A mRNA CTD PMID:25270620 NCBI chr 4:13,542,022...13,662,967
Ensembl chr 4:14,499,869...14,555,167 		JBrowse link
G Fam222a family with sequence similarity 222, member A decreases expression ISO Mannitol results in decreased expression of FAM222A mRNA CTD PMID:25270620 NCBI chr12:41,982,064...42,033,085
Ensembl chr12:47,647,405...47,693,703 		JBrowse link
G Fgf23 fibroblast growth factor 23 decreases export
decreases expression
multiple interactions 		EXP
ISO 		Mannitol results in decreased export of FGF23 protein
Mannitol results in decreased expression of FGF23 mRNA
Mannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 mRNA]; Mannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 protein] 		CTD PMID:37992803 NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Mannitol results in increased expression of FOS mRNA CTD PMID:11557636 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gal3st2 galactose-3-O-sulfotransferase 2 decreases expression ISO Mannitol results in decreased expression of GAL3ST2 mRNA CTD PMID:25270620 NCBI chr 9:94,382,456...94,387,990
Ensembl chr 9:101,823,815...101,836,507 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 decreases expression ISO Mannitol results in decreased expression of GAS2L2 mRNA CTD PMID:25270620 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,719,999...68,727,171 		JBrowse link
G Gpc6 glypican 6 increases expression ISO Mannitol results in increased expression of GPC6 mRNA CTD PMID:25270620 NCBI chr15:94,030,218...95,027,883
Ensembl chr15:100,437,943...101,435,027 		JBrowse link
G Gpr19 G protein-coupled receptor 19 decreases expression ISO Mannitol results in decreased expression of GPR19 mRNA CTD PMID:25270620 NCBI chr 4:169,442,278...169,468,805
Ensembl chr 4:169,436,658...169,471,249 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Mannitol results in increased expression of HMOX1 mRNA CTD PMID:11592956 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Mannitol results in increased expression of HPRT1 mRNA CTD PMID:25270620 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Hrh2 histamine receptor H 2 increases expression ISO Mannitol results in increased expression of HRH2 mRNA CTD PMID:25270620 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 protein] CTD PMID:16285992 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein] CTD PMID:10567913 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Rotenone inhibits the reaction [Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] CTD PMID:23867654 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Mannitol results in increased expression of JUN mRNA CTD PMID:11557636 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member increases expression ISO Mannitol results in increased expression of KHDC3 mRNA CTD PMID:25270620 NCBI chr 8:82,722,980...82,724,884
Ensembl chr 8:82,722,980...82,724,884 		JBrowse link
G Krtap11-1 keratin associated protein 11-1 increases expression ISO Mannitol results in increased expression of KRTAP11-1 mRNA CTD PMID:25270620 NCBI chr11:28,809,940...28,810,944
Ensembl chr11:42,296,147...42,297,496 		JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Mannitol results in decreased expression of LSM6 mRNA CTD PMID:25270620 NCBI chr19:46,002,592...46,017,152 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK1 protein] CTD PMID:10910949 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mta2 metastasis associated 1 family, member 2 increases expression ISO Mannitol results in increased expression of MTA2 mRNA CTD PMID:25270620 NCBI chr 1:215,267,286...215,276,008
Ensembl chr 1:215,267,046...215,276,062 		JBrowse link
G Myl9 myosin light chain 9 decreases phosphorylation EXP Mannitol results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410 		JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression ISO Mannitol results in increased expression of MYLK3 mRNA CTD PMID:25270620 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:37,865,141...37,915,827 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 increases expression ISO Mannitol results in increased expression of NAALAD2 mRNA CTD PMID:25270620 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:23,683,395...23,756,060 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 decreases expression ISO Mannitol results in decreased expression of NDUFA13 mRNA CTD PMID:25270620 NCBI chr16:19,560,526...19,567,500
Ensembl chr 7:32,257,006...32,257,492 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression
multiple interactions 		ISO
EXP 		Mannitol results in increased expression of NFAT5 mRNA
Mannitol results in increased expression of NFAT5 mRNA; Mannitol results in increased expression of NFAT5 protein
Mannitol inhibits the reaction [Sodium Chloride deficiency results in decreased expression of NFAT5 mRNA] 		CTD PMID:23867654 PMID:37992803 NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418 		JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression ISO Mannitol results in increased expression of NKG7 mRNA CTD PMID:25270620 NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562 		JBrowse link
G Nppa natriuretic peptide A increases expression ISO Mannitol results in increased expression of NPPA protein CTD PMID:2177369 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nts neurotensin increases transport EXP NTS protein results in increased transport of Mannitol CTD PMID:11208724 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961 		JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Pcp2 Purkinje cell protein 2 increases expression ISO Mannitol results in increased expression of PCP2 mRNA CTD PMID:25270620 NCBI chr12:6,479,554...6,481,550
Ensembl chr12:6,479,554...6,485,159 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression
decreases expression 		ISO Mannitol results in increased expression of PDCD4 mRNA
Mannitol results in decreased expression of PDCD4 mRNA 		CTD PMID:21873647 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked increases expression EXP Mannitol results in increased expression of PHEX mRNA CTD PMID:37992803 NCBI chr  X:41,422,561...41,671,226
Ensembl chr  X:41,426,101...41,671,226 		JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Mannitol results in decreased expression of PLCL2 mRNA CTD PMID:25270620 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,529,841...3,713,712 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 increases expression ISO Mannitol results in increased expression of PLEKHO1 mRNA CTD PMID:25270620 NCBI chr 2:186,233,435...186,242,114
Ensembl chr 2:186,233,452...186,241,354 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 increases expression ISO Mannitol results in increased expression of POU1F1 mRNA CTD PMID:25270620 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:16,763,552...16,781,292 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression ISO Mannitol results in decreased expression of PPP1R10 mRNA CTD PMID:25270620 NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit increases expression ISO Mannitol results in increased expression of PPP4C mRNA CTD PMID:25270620 NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCD protein] CTD PMID:16285992 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Ptger1 prostaglandin E receptor 1 increases expression EXP Mannitol results in increased expression of PTGER1 mRNA CTD PMID:12888618 NCBI chr19:41,374,983...41,379,593
Ensembl chr19:41,374,471...41,378,284 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP Mannitol results in decreased expression of PTGER4 mRNA CTD PMID:12888618 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein]; Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein CTD PMID:12011046 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ralgdsl3 ral guanine nucleotide dissociation stimulator like 3 increases expression ISO Mannitol results in increased expression of RGL3 mRNA CTD PMID:25270620 NCBI chr 8:20,500,846...20,520,471
Ensembl chr 8:28,776,909...28,796,771 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression ISO Mannitol results in decreased expression of RBL1 mRNA CTD PMID:25270620 NCBI chr 3:166,226,187...166,289,862
Ensembl chr 3:166,226,198...166,289,376 		JBrowse link
G Rbp2 retinol binding protein 2 decreases expression ISO Mannitol results in decreased expression of RBP2 mRNA CTD PMID:25270620 NCBI chr 8:107,958,670...107,983,850 JBrowse link
G Samd10 sterile alpha motif domain containing 10 decreases expression ISO Mannitol results in decreased expression of SAMD10 mRNA CTD PMID:25270620 NCBI chr 3:189,077,795...189,082,069
Ensembl chr 3:189,078,513...189,082,582 		JBrowse link
G Sbsn suprabasin decreases expression ISO Mannitol results in decreased expression of SBSN mRNA CTD PMID:25270620 NCBI chr 1:95,106,390...95,133,448
Ensembl chr 1:95,120,927...95,134,220 		JBrowse link
G Sele selectin E multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein] CTD PMID:16285992 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Sgsm3 small G protein signaling modulator 3 decreases expression ISO Mannitol results in decreased expression of SGSM3 mRNA CTD PMID:25270620 NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:114,394,813...114,424,489 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases activity
multiple interactions 		EXP Mannitol results in increased activity of SLC12A1 protein
[Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water 		CTD PMID:12433675 NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340 		JBrowse link
G Slc2a8 solute carrier family 2 member 8 decreases expression ISO Mannitol results in decreased expression of SLC2A8 mRNA CTD PMID:25270620 NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:36,672,591...36,682,194 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Stx8 syntaxin 8 decreases expression ISO Mannitol results in decreased expression of STX8 mRNA CTD PMID:25270620 NCBI chr10:53,154,572...53,393,912
Ensembl chr10:53,153,523...53,429,541 		JBrowse link
G Timd4 T-cell immunoglobulin and mucin domain containing 4 decreases expression ISO Mannitol results in decreased expression of TIMD4 mRNA CTD PMID:25270620 NCBI chr10:31,686,994...31,723,095
Ensembl chr10:31,686,862...31,723,077 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein] CTD PMID:19298665 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Mannitol results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression 		ISO Mannitol results in decreased expression of TPD52 mRNA
Mannitol results in increased expression of TPD52 mRNA 		CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
G Triml1 tripartite motif family-like 1 increases expression ISO Mannitol results in increased expression of TRIML1 mRNA CTD PMID:25270620 NCBI chr16:48,994,968...49,005,343
Ensembl chr16:55,729,691...55,737,769 		JBrowse link
G Ulbp1 UL16 binding protein 1 increases expression ISO Mannitol results in increased expression of ULBP1 mRNA CTD PMID:25270620 NCBI chr 1:1,694,255...1,716,160 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 protein] CTD PMID:16285992 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Wdr20 WD repeat domain 20 decreases expression ISO Mannitol results in decreased expression of WDR20 mRNA CTD PMID:25270620 NCBI chr 6:129,751,952...129,821,464
Ensembl chr 6:135,572,893...135,642,688 		JBrowse link
G Zfp13 zinc finger protein 13 decreases expression ISO Mannitol results in decreased expression of ZFP13 mRNA CTD PMID:25270620 NCBI chr10:13,119,707...13,128,284
Ensembl chr10:13,120,084...13,128,243 		JBrowse link
G Zg16 zymogen granule protein 16 decreases expression ISO Mannitol results in decreased expression of ZG16 mRNA CTD PMID:25270620 NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:191,088,248...191,090,605 		JBrowse link
sodium hydrogencarbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Sodium Bicarbonate results in increased expression of ABCC2 mRNA CTD PMID:29126803 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression EXP Sodium Bicarbonate results in decreased expression of ABCG2 mRNA CTD PMID:29126803 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Sodium Bicarbonate results in decreased expression of CAR2 mRNA CTD PMID:31569818 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Cat catalase multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in decreased activity of CAT protein CTD PMID:25559736 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of FN1 protein] CTD PMID:10430982 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Sodium Bicarbonate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] CTD PMID:25559736 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA] CTD PMID:25559736 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC15A1 mRNA CTD PMID:29126803 NCBI chr15:104,944,461...104,991,316
Ensembl chr15:104,944,463...104,989,369 		JBrowse link
G Slc22a19 solute carrier family 22, member 19 increases expression EXP Sodium Bicarbonate results in increased expression of SLC22A24 mRNA CTD PMID:29126803 NCBI chr 1:214,339,594...214,394,681
Ensembl chr 1:214,339,599...214,394,681 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC22A6 mRNA CTD PMID:29126803 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions EXP SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of Cadmium Chloride]; SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of manganese chloride] CTD PMID:21509381 NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC4A1 mRNA CTD PMID:31569818 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases transport
decreases expression 		ISO
EXP 		SLC4A4 protein results in increased transport of Sodium Bicarbonate
Sodium Bicarbonate results in decreased expression of SLC4A4 mRNA 		CTD PMID:18614622 PMID:31569818 NCBI chr14:19,125,394...19,577,379
Ensembl chr14:19,129,264...19,577,435 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP Sodium Bicarbonate results in decreased expression of SLCO1A1 mRNA CTD PMID:29126803 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of TGFB1 mRNA] CTD PMID:10430982 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA] CTD PMID:25559736 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA] CTD PMID:25559736 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vim vimentin multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of VIM protein] CTD PMID:10430982 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
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  CHEBI ontology 20862
    role 20820
      application 20621
        anticaking agent 208
          food anticaking agent + 208
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