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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ophiobolin A
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Accession:CHEBI:7777 term browser browse the term
Definition:A sesterterpenoid that is ophiobolane with a hydroxy group at position 3, oxo groups at positions 5 and 25, double bonds at positions 7-8 and 19-20, and an oxygen link between positions 14 and 18.
Synonyms:exact_synonym: (18R)-3-hydroxy-5-oxo-14,18-epoxyophiobola-7,19-dien-25-al
 related_synonym: (18R)-14,18-epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al;   Formula=C25H36O4;   InChI=1S/C25H36O4/c1-15(2)10-18-11-16(3)25(29-18)9-8-23(4)12-19-22(20(27)13-24(19,5)28)17(14-26)6-7-21(23)25/h6,10,14,16,18-19,21-22,28H,7-9,11-13H2,1-5H3/b17-6-/t16-,18-,19-,21+,22+,23+,24+,25-/m0/s1;   InChIKey=MWYYLZRWWNBROW-BDZRSQQBSA-N;   SMILES=[H][C@@]1(C[C@H](C)[C@]2(CC[C@]3(C)C[C@@]4([H])[C@]([H])(C(=O)C[C@@]4(C)O)\\C(C=O)=C/C[C@@]23[H])O1)C=C(C)C;   cochliobolin;   cochliobolin A;   ophiobolin
 xref: Beilstein:48792;   CAS:4611-05-6;   KEGG:C09145;   KNApSAcK:C00003460;   LIPID_MAPS_instance:LMPR0105050001
 xref_mesh: MESH:C040764



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ophiobolin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    chemical entity 19913
      atom 19895
        nonmetal atom 19817
          carbon atom 19770
            organic molecular entity 19770
              olefinic compound 16998
                enal 3107
                  ophiobolin A 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19542
                              organochalcogen compound 19302
                                organooxygen compound 19218
                                  carbon oxoacid 18664
                                    carboxylic acid 18661
                                      carboacyl group 17700
                                        univalent carboacyl group 17700
                                          formyl group 9048
                                            aldehyde 9048
                                              alpha,beta-unsaturated aldehyde 3107
                                                enal 3107
                                                  ophiobolin A 1
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