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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bongkrekic acid
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Accession:CHEBI:77742 term browser browse the term
Definition:A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group. It is produced by the bacterium Burkholderia gladioli and implicated in outbreaks of food-borne illness involving coconut and corn-based products in Indonesia and China.
Synonyms:exact_synonym: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid
 related_synonym: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-2,4,8,10,14,18,20-docosaheptaenedioic acid;   Formula=C28H38O7;   InChI=1S/C28H38O7/c1-21(15-18-24(19-26(29)30)20-27(31)32)13-11-9-7-5-6-8-10-12-14-25(35-4)22(2)16-17-23(3)28(33)34/h6,8-12,15-19,21,25H,5,7,13-14,20H2,1-4H3,(H,29,30)(H,31,32)(H,33,34)/b8-6+,11-9+,12-10-,18-15+,22-16-,23-17+,24-19+/t21-,25+/m0/s1;   InChIKey=SHCXABJSXUACKU-WUTQZGRKSA-N;   SMILES=CO[C@H](C\\C=C/C=C/CC\\C=C\\C[C@H](C)\\C=C\\C(\\CC(O)=O)=C/C(O)=O)C(\\C)=C/C=C(\\C)C(O)=O;   bongkrek acid
 xref: CAS:11076-19-0;   CBA:366918;   Chemspider:4938689
 xref_mesh: MESH:D001865
 xref: PDBeChem:BKC;   PMID:12034471;   PMID:15919152;   PMID:16430940;   PMID:17123460;   PMID:20237660;   PMID:2037079;   PMID:22050912;   PMID:22998163;   PMID:22999884;   PMID:23315986;   PMID:24522192;   PMID:25786526;   PMID:26032198;   PMID:26126659;   PMID:26548846;   PMID:27798877;   PMID:27823840;   PMID:28105575;   PMID:28769000;   PMID:29155976;   PMID:30611538;   PMID:31517068;   PMID:31518860;   PMID:31524538;   PMID:31642300;   PMID:33246684;   PMID:33459584;   PMID:34019862;   PMID:34079526;   PMID:7164105;   Patent:JP2005068064;   Reaxys:1717902;   Wikipedia:Bongkrek_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:178020


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bongkrekic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Bongkrekic Acid results in increased expression of ADIPOQ mRNA CTD PMID:25786526 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of DDIT3 protein] CTD PMID:29427785 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Bongkrekic Acid inhibits the reaction [N-caproylsphingosine results in increased expression of ICAM1 mRNA] CTD PMID:12952965 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il24 interleukin 24 decreases activity ISO Bongkrekic Acid results in decreased activity of IL24 protein CTD PMID:14678967 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions EXP Bongkrekic Acid inhibits the reaction [[Diamide co-treated with Glutathione] results in increased activity of MGST1 protein] CTD PMID:18634816 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875 		JBrowse link
G P2rx1 purinergic receptor P2X 1 increases activity ISO Bongkrekic Acid results in increased activity of P2RX1 protein CTD PMID:34019862 NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164 		JBrowse link
G Padi4 peptidyl arginine deiminase 4 increases activity ISO Bongkrekic Acid results in increased activity of PADI4 protein CTD PMID:34019862 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:158,324,417...158,360,422 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO Bongkrekic Acid analog results in increased activity of PPARG protein; Bongkrekic Acid results in increased activity of PPARG protein CTD PMID:25786526 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions EXP Bongkrekic Acid inhibits the reaction [oxophenylarsine binds to SLC25A4 protein] CTD PMID:18667415 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases activity ISO Bongkrekic Acid results in decreased activity of SLC25A5 protein CTD PMID:26746582 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:120,897,563...120,900,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        poison 19105
          toxin 16258
            bongkrekic acid 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      tricarboxylic acid 2536
                                        bongkrekic acid 11
paths to the root