CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: lead tetraacetate
Accession: CHEBI:77245
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Definition: An acetate salt with formula Pb(OAc)4. It is used as a selective oxidising agent in organic synthesis.
Synonyms: exact_synonym: lead(4+) tetraacetate; tetraacetoxyplumbane
related_synonym: (AcO)4Pb; (CH3CO2)4Pb; (CH3COO)4Pb; Formula=C8H12O8Pb; InChI=1S/4C2H4O2.Pb/c4*1-2(3)4;/h4*1H3,(H,3,4);/q;;;;+4/p-4; InChIKey=JEHCHYAKAXDFKV-UHFFFAOYSA-J; Pb(OAc)4; SMILES=CC(=O)O[Pb](OC(C)=O)(OC(C)=O)OC(C)=O; lead(IV) acetate; plumbic acetate
xref: CAS:546-67-8
xref_mesh: MESH:C029433
xref: PMID:13486316; PMID:14431883; PMID:56394; PMID:5681783; PMID:5908761; PMID:6051709; PMID:6056485; PMID:864328; PMID:8864225; Reaxys:10774911; Reaxys:16508369; Reaxys:3595640; Wikipedia:Lead(IV)_acetate
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App
amyloid beta precursor protein
decreases expression
ISO
lead tetraacetate results in decreased expression of APP mRNA
CTD
PMID:20865013
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Mapt
microtubule-associated protein tau
decreases expression
ISO
lead tetraacetate results in decreased expression of MAPT mRNA
CTD
PMID:20865013
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Nrxn1
neurexin 1
decreases expression
ISO
lead tetraacetate results in decreased expression of NRXN1 mRNA
CTD
PMID:20865013
NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
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Prnp
prion protein
decreases expression
ISO
lead tetraacetate results in decreased expression of PRNP mRNA
CTD
PMID:20865013
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Syp
synaptophysin
decreases expression
ISO
lead tetraacetate results in decreased expression of SYP mRNA
CTD
PMID:20865013
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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Tubb3
tubulin, beta 3 class III
decreases expression
ISO
lead tetraacetate results in decreased expression of TUBB3 mRNA
CTD
PMID:20865013
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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