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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ginsenoside Rb2
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Accession:CHEBI:77152 term browser browse the term
Definition:A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.
Synonyms:exact_synonym: (3beta,12beta)-20-{[6-O-(alpha-L-arabinopyranosyl)-beta-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
 related_synonym: (20S)-ginsenoside Rb2;   Formula=C53H90O22;   Ginsenoside C;   InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1;   InChIKey=NODILNFGTFIURN-GZPRDHCNSA-N;   NSC 308878;   SMILES=CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@@H]3CC[C@@]21C
 xref: CAS:11021-13-9;   HMDB:HMDB0034996
 xref_mesh: MESH:C048026
 xref: MetaCyc:CPD-15451;   PMID:21811908;   PMID:21811928;   PMID:22031031;   PMID:22534302;   PMID:22717707;   PMID:23271644;   PMID:23670791;   PMID:23717160;   PMID:24369998;   PMID:8798715;   Patent:WO2006001654;   Reaxys:4901741


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ginsenoside Rb2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP ginsenoside Rb2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Lpl lipoprotein lipase increases secretion
decreases secretion		 ISO ginsenoside Rb2 results in increased secretion of LPL protein
ginsenoside Rb2 results in decreased secretion of LPL protein		 CTD PMID:8988629 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19868
      biological role 19866
        antimicrobial agent 18260
          antiviral agent 11341
            ginsenoside Rb2 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19771
                          organic molecular entity 19771
                            heteroorganic entity 19528
                              organochalcogen compound 19290
                                organooxygen compound 19206
                                  carbohydrates and carbohydrate derivatives 15297
                                    carbohydrate 15297
                                      monosaccharide 4879
                                        aldose 3234
                                          aldohexose 2886
                                            glucose 2839
                                              D-glucose 2837
                                                D-glucopyranose 1814
                                                  beta-D-glucose 1663
                                                    beta-D-glucoside 1470
                                                      ginsenoside Rb2 2
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