EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	*EC 1.3.3. (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor**	go back to main search page
Accession:	CHEBI:76860	browse the term
Definition:	An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.3.3.*).
Synonyms:	related_synonym:	EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitors; EC 1.3.3.* inhibitor; EC 1.3.3.* inhibitors; oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.) inhibitor; oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.) inhibitors

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Rat (1334) Mouse (1303) Human (1311) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (1) Green Monkey (0) Naked Mole-rat (0) All
Genes (1334)

acifluorfen

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2, apoptosis regulator

decreases response to substance

BCL2 protein results in decreased susceptibility to acifluorfen

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
increases expression

NR1I3 gene mutant form inhibits the reaction [acifluorfen results in increased expression of CYP2B10 mRNA]

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
decreases response to substance

NR1I3 gene mutant form inhibits the reaction [acifluorfen results in increased expression of CYP2B10 mRNA]
NR1I3 gene mutant form results in decreased susceptibility to acifluorfen

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

poly (ADP-ribose) polymerase 1

increases expression

acifluorfen results in increased expression of PARP1 protein modified form

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

protoporphyrinogen oxidase

decreases activity

acifluorfen results in decreased activity of PPOX protein

NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805

aclonifen

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nuclear receptor subfamily 1, group I, member 3

increases activity

aclonifen results in increased activity of NR1I3 protein

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

butafenacil

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nuclear receptor subfamily 1, group I, member 2

increases activity

butafenacil results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

chlornitrofen

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

multiple interactions
affects binding

2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of AR protein; 2,4,6-trichlorophenyl 4-nitrophenyl ether inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of AR protein]
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to AR protein

PMID:12676605 PMID:15064155

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

C-C motif chemokine ligand 2

increases expression

2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 mRNA; 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 protein

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

early growth response 1

increases expression

2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

estrogen receptor 1

multiple interactions
increases activity
affects binding

2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to ESR1 protein

PMID:12676605 PMID:15064155

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

growth arrest and DNA-damage-inducible, alpha

increases expression

2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases activity

2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of NR1I3 protein

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

tumor necrosis factor

increases expression

2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

epyrifenacil

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

protoporphyrinogen oxidase

decreases activity

epyrifenacil metabolite results in decreased activity of PPOX protein; epyrifenacil results in decreased activity of PPOX protein

NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805

G

solute carrier organic anion transporter family, member 1a4

increases uptake
multiple interactions

SLCO1A4 protein results in increased uptake of epyrifenacil metabolite
Digoxin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]; Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

solute carrier organic anion transporter family member 1B2

increases uptake
multiple interactions

SLCO1B2 protein results in increased uptake of epyrifenacil metabolite
SLCO1B3 protein results in increased uptake of epyrifenacil metabolite
Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]
Rifampin inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]

NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981

fomesafen

term browser

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Object Name

Qualifiers

Evidence

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Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily D member 3

increases expression

fomesafen results in increased expression of ABCD3 mRNA

NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020

G

acyl-CoA thioesterase 1

increases expression

fomesafen results in increased expression of ACOT1 mRNA

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA oxidase 1

increases expression

fomesafen results in increased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

5'-aminolevulinate synthase 1

increases expression

fomesafen results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

uroporphyrinogen decarboxylase

decreases activity

fomesafen results in decreased activity of UROD protein

NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808

nitrofen

term browser

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Object Name

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Evidence

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Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APOBEC1 complementation factor

increases expression

nitrofen results in increased expression of A1CF mRNA

NCBI chr 1:229,736,037...229,823,499
Ensembl chr 1:229,736,106...229,824,354

G

alpha-2-macroglobulin

increases expression

nitrofen results in increased expression of A2M mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

aminoadipate aminotransferase

increases expression

nitrofen results in increased expression of AADAT mRNA

NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332

G

ATP binding cassette subfamily B member 11

increases expression

nitrofen results in increased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily C member 2

increases expression

nitrofen results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily G member 2

increases expression

nitrofen results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ATP binding cassette subfamily G member 4

decreases expression

nitrofen results in decreased expression of ABCG4 mRNA

NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881

G

abhydrolase domain containing 2, acylglycerol lipase

decreases expression

nitrofen results in decreased expression of ABHD2 mRNA

NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061

G

acetyl-CoA acyltransferase 2

increases expression

nitrofen results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acyl-CoA dehydrogenase, long chain

increases expression

nitrofen results in increased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

aggrecan

decreases expression

nitrofen results in decreased expression of ACAN mRNA

NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627

G

angiotensin I converting enzyme

decreases activity

nitrofen results in decreased activity of ACE protein

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

atypical chemokine receptor 2

increases expression

nitrofen results in increased expression of ACKR2 mRNA

NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582

G

acyl-CoA thioesterase 12

increases expression

nitrofen results in increased expression of ACOT12 mRNA

NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536

G

acyl-CoA oxidase 2

increases expression

nitrofen results in increased expression of ACOX2 mRNA

NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160

G

acid phosphatase 5, tartrate resistant

increases expression

nitrofen results in increased expression of ACP5 mRNA

NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929

G

acyl-CoA synthetase bubblegum family member 2

increases expression

nitrofen results in increased expression of ACSBG2 mRNA

NCBI chr 9:1,683,846...1,715,517
Ensembl chr 9:1,683,847...1,714,518

G

acyl-CoA synthetase long-chain family member 1

increases expression

nitrofen results in increased expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase medium-chain family member 1

increases expression

nitrofen results in increased expression of ACSM1 mRNA

NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495

G

acyl-CoA synthetase medium-chain family member 3

increases expression

nitrofen results in increased expression of ACSM3 mRNA

NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184

G

actin alpha 2, smooth muscle

increases expression

nitrofen results in increased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, alpha, cardiac muscle 1

decreases expression
increases expression

nitrofen results in decreased expression of ACTC1 mRNA
nitrofen results in increased expression of ACTC1 mRNA

PMID:26720608 PMID:33484710

NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523

G

actin gamma 2, smooth muscle

decreases expression

nitrofen results in decreased expression of ACTG2 mRNA

PMID:26720608 PMID:33484710

NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465

G

actinin alpha 2

increases expression

nitrofen results in increased expression of ACTN2 mRNA

NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622

G

activin A receptor like type 1

increases expression

nitrofen results in increased expression of ACVRL1 mRNA; nitrofen results in increased expression of ACVRL1 protein

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

ADAM metallopeptidase with thrombospondin type 1 motif, 14

decreases expression

nitrofen results in decreased expression of ADAMTS14 mRNA

NCBI chr20:29,143,029...29,219,846
Ensembl chr20:29,144,354...29,219,866

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

decreases expression

nitrofen results in decreased expression of ADAMTS15 mRNA

NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249

G

ArfGAP with dual PH domains 2

increases expression

nitrofen results in increased expression of ADAP2 mRNA

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

adenosine deaminase, RNA-specific, B1

decreases expression

nitrofen results in decreased expression of ADARB1 mRNA

NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852

G

aarF domain containing kinase 2

decreases expression

nitrofen results in decreased expression of ADCK2 mRNA

NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608

G

adenylate cyclase 5

decreases expression

nitrofen results in decreased expression of ADCY5 mRNA

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

G

adducin 2

increases expression

nitrofen results in increased expression of ADD2 mRNA

NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505

G

adhesion G protein-coupled receptor L2

decreases expression

nitrofen results in decreased expression of ADGRL2 mRNA

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

increases expression

nitrofen results in increased expression of ADH1 mRNA

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

adiponectin, C1Q and collagen domain containing

increases expression

nitrofen results in increased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adrenomedullin

increases expression

nitrofen results in increased expression of ADM mRNA; nitrofen results in increased expression of ADM protein

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

2-aminoethanethiol dioxygenase

increases expression

nitrofen results in increased expression of ADO mRNA

NCBI chr20:21,044,815...21,045,983
Ensembl chr20:21,044,555...21,049,235

G

androgen-dependent TFPI-regulating protein

increases expression

nitrofen results in increased expression of ADTRP mRNA

NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826

G

actin filament associated protein 1-like 2

decreases expression

nitrofen results in decreased expression of AFAP1L2 mRNA

NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820

G

arylformamidase

increases expression

nitrofen results in increased expression of AFMID mRNA

NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718

G

alpha-fetoprotein

increases expression

nitrofen results in increased expression of AFP mRNA

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

advanced glycosylation end product-specific receptor

increases expression

nitrofen results in increased expression of AGER mRNA

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

nitrofen results in decreased expression of AGPAT1 mRNA

NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278

G

anterior gradient 2, protein disulphide isomerase family member

increases expression

nitrofen results in increased expression of AGR2 mRNA

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

angiotensinogen

decreases expression

nitrofen results in decreased expression of AGT mRNA

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

decreases expression
increases expression

nitrofen results in decreased expression of AGTR1A mRNA
nitrofen results in increased expression of AGTR1A mRNA

PMID:15578192 PMID:16292651 PMID:33484710

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

angiotensin II receptor, type 1b

decreases expression

nitrofen results in decreased expression of AGTR1B mRNA

NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232

G

angiotensin II receptor, type 2

decreases expression

nitrofen results in decreased expression of AGTR2 mRNA

PMID:15578192 PMID:16292651

NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057

G

angiotensin II receptor-associated protein

decreases expression

nitrofen results in decreased expression of AGTRAP mRNA

NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036

G

alanine-glyoxylate aminotransferase 2

increases expression

nitrofen results in increased expression of AGXT2 mRNA

NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926

G

adenosylhomocysteinase

increases expression

nitrofen results in increased expression of AHCY mRNA

NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393

G

AT hook, DNA binding motif, containing 1

decreases expression

nitrofen results in decreased expression of AHDC1 mRNA

NCBI chr 5:145,228,228...145,294,170
Ensembl chr 5:145,228,227...145,294,145

G

alpha-2-HS-glycoprotein

increases expression

nitrofen results in increased expression of AHSG mRNA

NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999

G

alpha hemoglobin stabilizing protein

increases expression

nitrofen results in increased expression of AHSP mRNA

NCBI chr 1:182,879,901...182,885,508
Ensembl chr 1:182,880,076...182,885,506

G

allograft inflammatory factor 1

increases expression

nitrofen results in increased expression of AIF1 mRNA

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

apoptosis inducing factor, mitochondria associated 1

affects localization
multiple interactions

nitrofen affects the localization of AIFM1 protein
SB 203580 inhibits the reaction [nitrofen affects the localization of AIFM1 protein]

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

adherens junctions associated protein 1

increases expression

nitrofen results in increased expression of AJAP1 mRNA

NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:163,907,847...164,020,317

G

adenylate kinase 4

increases expression

nitrofen results in increased expression of AK4 mRNA

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

A-kinase anchoring protein 6

decreases expression

nitrofen results in decreased expression of AKAP6 mRNA

NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738

G

aldo-keto reductase family 1, member C15

increases expression

nitrofen results in increased expression of AKR1C15 mRNA

NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061

G

aldo-keto reductase family 1, member D1

increases expression

nitrofen results in increased expression of AKR1D1 mRNA

NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372

G

AKT serine/threonine kinase 2

decreases expression
multiple interactions

nitrofen results in decreased expression of AKT2 mRNA
[nitrofen co-treated with Tretinoin] results in increased expression of AKT2 mRNA

PMID:20152353 PMID:20623292

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

aminolevulinate dehydratase

increases expression

nitrofen results in increased expression of ALAD mRNA

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

5'-aminolevulinate synthase 2

increases expression

nitrofen results in increased expression of ALAS2 mRNA

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

albumin

increases expression

nitrofen results in increased expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A2

decreases activity

nitrofen results in decreased activity of ALDH1A2 protein

NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107

G

aldehyde dehydrogenase 1 family, member A3

increases expression
multiple interactions
decreases expression

nitrofen results in increased expression of ALDH1A3 mRNA
Tretinoin promotes the reaction [nitrofen results in increased expression of ALDH1A3 mRNA]
nitrofen results in decreased expression of ALDH1A3 protein

PMID:17270546 PMID:24972641 PMID:26672737

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 1 family, member L2

decreases expression

nitrofen results in decreased expression of ALDH1L2 mRNA

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 4 family, member A1

increases expression

nitrofen results in increased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

aldehyde dehydrogenase 8 family, member A1

increases expression

nitrofen results in increased expression of ALDH8A1 mRNA

NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385

G

aldolase, fructose-bisphosphate B

increases expression

nitrofen results in increased expression of ALDOB mRNA

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

alkB homolog 7

increases expression

nitrofen results in increased expression of ALKBH7 mRNA

NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044

G

alpha-1-microglobulin/bikunin precursor

increases expression

nitrofen results in increased expression of AMBP mRNA

NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331

G

amidohydrolase domain containing 1

increases expression

nitrofen results in increased expression of AMDHD1 mRNA

NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156

G

angiopoietin-like 2

decreases expression

nitrofen results in decreased expression of ANGPTL2 mRNA

NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178

G

angiopoietin-like 3

increases expression

nitrofen results in increased expression of ANGPTL3 mRNA

NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957

G

angiopoietin-like 8

increases expression

nitrofen results in increased expression of ANGPTL8 mRNA

NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490

G

ankyrin repeat domain 1

increases expression

nitrofen results in increased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat domain 16

increases expression

nitrofen results in increased expression of ANKRD16 mRNA

NCBI chr17:66,735,325...66,748,533
Ensembl chr17:66,737,261...66,748,533

G

ankyrin repeat domain 37

increases expression

nitrofen results in increased expression of ANKRD37 mRNA

NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963

G

ankyrin repeat and sterile alpha motif domain containing 1B

increases expression

nitrofen results in increased expression of ANKS1B mRNA

NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693

G

apelin

decreases expression

nitrofen results in decreased expression of APLN mRNA; nitrofen results in decreased expression of APLN protein

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

G

apelin receptor

decreases expression
increases expression

nitrofen results in decreased expression of APLNR mRNA; nitrofen results in decreased expression of APLNR protein
nitrofen results in increased expression of APLNR mRNA

PMID:20638522 PMID:24363088 PMID:33484710

NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050

G

apolipoprotein A1

increases expression

nitrofen results in increased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein A2

increases expression

nitrofen results in increased expression of APOA2 mRNA

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein B

increases expression

nitrofen results in increased expression of APOB mRNA

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

apolipoprotein B mRNA editing enzyme catalytic subunit 2

increases expression

nitrofen results in increased expression of APOBEC2 mRNA

NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458

G

apolipoprotein C1

increases expression

nitrofen results in increased expression of APOC1 mRNA

NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375

G

apolipoprotein C2

increases expression

nitrofen results in increased expression of APOC2 mRNA

NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476

G

apolipoprotein C3

increases expression

nitrofen results in increased expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein C4

increases expression

nitrofen results in increased expression of APOC4 mRNA

NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981

G

apolipoprotein D

decreases expression

nitrofen results in decreased expression of APOD mRNA

NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305

G

apolipoprotein E

increases expression

nitrofen results in increased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

apolipoprotein F

increases expression

nitrofen results in increased expression of APOF mRNA

NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946

G

apolipoprotein H

increases expression

nitrofen results in increased expression of APOH mRNA

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

G

apolipoprotein L2

decreases expression

nitrofen results in decreased expression of APOL3 mRNA

NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558

G

apolipoprotein M

increases expression

nitrofen results in increased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

aquaporin 1

decreases expression

nitrofen results in decreased expression of AQP1 mRNA; nitrofen results in decreased expression of AQP1 protein

PMID:20638522 PMID:26720608

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

increases expression

nitrofen results in increased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 4

decreases expression
increases expression

nitrofen results in decreased expression of AQP4 mRNA
nitrofen results in increased expression of AQP4 mRNA

PMID:20638522 PMID:33484710

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

aquaporin 5

decreases expression

nitrofen results in decreased expression of AQP5 mRNA; nitrofen results in decreased expression of AQP5 protein

PMID:17245593 PMID:17270560

NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209

G

aquaporin 8

increases expression

nitrofen results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

aquaporin 9

increases expression

nitrofen results in increased expression of AQP9 mRNA

NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395

G

androgen receptor

multiple interactions
affects binding

Dihydrotestosterone inhibits the reaction [nitrofen results in increased activity of AR protein]; nitrofen inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nitrofen inhibits the reaction [Androgens binds to AR protein]; nitrofen inhibits the reaction [Metribolone results in increased activity of AR protein]
nitrofen binds to AR protein

PMID:15064155 PMID:15253041 PMID:18324785 PMID:33049310

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

arginase 1

increases expression

nitrofen results in increased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GTPase activating protein 18

increases expression

nitrofen results in increased expression of ARHGAP18 mRNA

NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256

G

Rho GTPase activating protein 20

decreases expression

nitrofen results in decreased expression of ARHGAP20 mRNA

NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739

G

Rho GTPase activating protein 42

decreases expression

nitrofen results in decreased expression of ARHGAP42 mRNA

NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870

G

cAMP regulated phosphoprotein 21

decreases expression

nitrofen results in decreased expression of ARPP21 mRNA

NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297

G

ADP-ribosyltransferase 3

increases expression

nitrofen results in increased expression of ART3 mRNA

NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407

G

ADP-ribosyltransferase 4

decreases expression

nitrofen results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

ankyrin repeat and SOCS box containing 15

decreases expression

nitrofen results in decreased expression of ASB15 mRNA

NCBI chr 4:53,021,553...53,050,846
Ensembl chr 4:53,031,692...53,049,928

G

ankyrin repeat and SOCS box-containing 2

decreases expression

nitrofen results in decreased expression of ASB2 mRNA

NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854

G

achaete-scute family bHLH transcription factor 1

decreases expression

nitrofen results in decreased expression of ASCL1 mRNA

NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993

G

asialoglycoprotein receptor 1

increases expression

nitrofen results in increased expression of ASGR1 mRNA

NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631

G

asialoglycoprotein receptor 2

increases expression

nitrofen results in increased expression of ASGR2 mRNA

NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617

G

acetylserotonin O-methyltransferase-like

increases expression

nitrofen results in increased expression of ASMTL mRNA

NCBI chr12:16,315,335...16,318,083
Ensembl chr12:16,315,414...16,318,080

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

nitrofen results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

argininosuccinate synthase 1

increases expression

nitrofen results in increased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 3

increases expression

nitrofen results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

autophagy related 16-like 2

increases expression

nitrofen results in increased expression of ATG16L2 mRNA

NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420

G

ATPase phospholipid transporting 10A (putative)

decreases expression

nitrofen results in decreased expression of ATP10A mRNA

NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:109,556,782...109,730,437

G

ATPase phospholipid transporting 10B

decreases expression

nitrofen results in decreased expression of ATP10B mRNA

NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

decreases expression

nitrofen results in decreased expression of ATP2A1 mRNA

NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases expression

nitrofen results in increased expression of ATP2A2 mRNA

NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101

G

ATPase plasma membrane Ca2+ transporting 2

increases expression

nitrofen results in increased expression of ATP2B2 mRNA

NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665

G

ATP synthase membrane subunit c locus 1

increases expression

nitrofen results in increased expression of ATP5MC1 mRNA

NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase membrane subunit e

increases expression

nitrofen results in increased expression of ATP5ME mRNA

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

ATP synthase peripheral stalk-membrane subunit b

increases expression

nitrofen results in increased expression of ATP5PB mRNA

NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418

G

ATPase H+ transporting accessory protein 1 like

increases expression

nitrofen results in increased expression of ATP6AP1L mRNA

NCBI chr 2:22,037,542...22,079,376
Ensembl chr 2:22,037,563...22,065,038

G

ATPase copper transporting alpha

decreases expression

nitrofen results in decreased expression of ATP7A mRNA; nitrofen results in decreased expression of ATP7A protein

NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354

G

ATPase copper transporting beta

increases expression

nitrofen results in increased expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

ataxin 7-like 2

decreases expression

nitrofen results in decreased expression of ATXN7L2 mRNA

NCBI chr 2:195,838,920...195,847,339
Ensembl chr 2:195,838,981...195,847,315

G

alpha-2-glycoprotein 1, zinc-binding

increases expression

nitrofen results in increased expression of AZGP1 mRNA

NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091

G

Beta-1,3-galactosyltransferase 1

increases expression

nitrofen results in increased expression of B3GALT1 mRNA

NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

decreases expression

nitrofen results in decreased expression of B3GNT7 mRNA

NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

FOXA2 protein inhibits the reaction [nitrofen results in increased expression of BAX protein]; MIR130A mRNA affects the reaction [nitrofen results in increased expression of BAX protein]

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

bromodomain adjacent to zinc finger domain, 2A

decreases expression

nitrofen results in decreased expression of BAZ2A mRNA

NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659

G

gamma-butyrobetaine hydroxylase 1

increases expression

nitrofen results in increased expression of BBOX1 mRNA

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

BCAR3 adaptor protein, NSP family member

decreases expression

nitrofen results in decreased expression of BCAR3 mRNA

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

nitrofen results in decreased expression of BCL2 protein
FOXA2 protein inhibits the reaction [nitrofen results in decreased expression of BCL2 protein]

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

nitrofen results in decreased expression of BCL2L1 protein

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

BCL6, transcription repressor

decreases expression

nitrofen results in decreased expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

beta-carotene oxygenase 1

increases expression

nitrofen results in increased expression of BCO1 protein

NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101

G

beta-carotene oxygenase 2

increases expression

nitrofen results in increased expression of BCO2 protein

NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467

G

BCL6 co-repressor-like 1

decreases expression

nitrofen results in decreased expression of BCORL1 mRNA

NCBI chr X:127,516,504...127,584,529
Ensembl chr X:127,537,538...127,584,087

G

3-hydroxybutyrate dehydrogenase 1

increases expression

nitrofen results in increased expression of BDH1 mRNA

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

BEN domain containing 6

decreases expression

nitrofen results in decreased expression of BEND6 mRNA

NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:36,081,484...36,135,228

G

brain expressed X-linked 2

increases expression

nitrofen results in increased expression of BEX1 mRNA

NCBI chr X:99,019,847...99,021,375
Ensembl chr X:99,019,000...99,021,503

G

brain expressed, X-linked 4

increases expression

nitrofen results in increased expression of BEX4 mRNA

NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531

G

betaine-homocysteine S-methyltransferase

increases expression

nitrofen results in increased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

bone morphogenetic protein 10

increases expression

nitrofen results in increased expression of BMP10 mRNA

NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627

G

bone morphogenetic protein 3

decreases expression

nitrofen results in decreased expression of BMP3 mRNA

NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153

G

bone morphogenetic protein 4

decreases expression

nitrofen results in decreased expression of BMP4 mRNA

PMID:17270562 PMID:18280291

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bone morphogenetic protein receptor type 2

decreases expression

nitrofen results in decreased expression of BMPR2 mRNA; nitrofen results in decreased expression of BMPR2 protein

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

G

BCL2 interacting protein 3

increases expression

nitrofen results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

biphenyl hydrolase like

increases expression

nitrofen results in increased expression of BPHL mRNA

NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288

G

BRF1 general transcription factor IIIB subunit

decreases expression

nitrofen results in decreased expression of BRF1 mRNA

NCBI chr 6:132,034,378...132,081,313
Ensembl chr 6:132,037,272...132,081,278

G

BR serine/threonine kinase 1

decreases expression

nitrofen results in decreased expression of BRSK1 mRNA

NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365

G

bromodomain and WD repeat domain containing 1

decreases expression

nitrofen results in decreased expression of BRWD1 mRNA

NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768

G

bone marrow stromal cell antigen 2

increases expression

nitrofen results in increased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

BTB domain containing 16

increases expression

nitrofen results in increased expression of BTBD16 mRNA

NCBI chr 1:185,334,971...185,389,518
Ensembl chr 1:185,335,725...185,389,517

G

similar to human chromosome 14 open reading frame 93

decreases expression

nitrofen results in decreased expression of C15H14ORF93 mRNA

NCBI chr15:28,037,567...28,064,347
Ensembl chr15:28,037,574...28,064,274

G

complement C1q B chain

increases expression

nitrofen results in increased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

similar to human chromosome 4 open reading frame 46

decreases expression

nitrofen results in decreased expression of C2H4ORF46 mRNA

NCBI chr 2:164,762,994...164,766,126
Ensembl chr 2:164,762,960...164,766,128

G

complement C3

increases expression

nitrofen results in increased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement component 4 binding protein, alpha

increases expression

nitrofen results in increased expression of C4BPA mRNA

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

G

complement component 4 binding protein, beta

increases expression

nitrofen results in increased expression of C4BPB mRNA

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

complement C5 like 1

increases expression

nitrofen results in increased expression of C5L1 mRNA

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

G

complement C6

increases expression

nitrofen results in increased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

complement C8 alpha chain

increases expression

nitrofen results in increased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

complement C8 beta chain

increases expression

nitrofen results in increased expression of C8B mRNA

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

G

complement C8 gamma chain

increases expression

nitrofen results in increased expression of C8G mRNA

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

G

ciliary associated calcium binding coiled-coil 1

increases expression

nitrofen results in increased expression of CABCOCO1 mRNA

NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725

G

calcium voltage-gated channel subunit alpha1 D

decreases expression

nitrofen results in decreased expression of CACNA1D mRNA

NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215

G

calcitonin-related polypeptide alpha

increases expression

nitrofen results in increased expression of CALCA mRNA

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

calcium/calmodulin-dependent protein kinase II gamma

decreases expression

nitrofen results in decreased expression of CAMK2G mRNA

NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050

G

calcium/calmodulin-dependent protein kinase IV

decreases expression

nitrofen results in decreased expression of CAMK4 mRNA

NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487

G

cathelicidin antimicrobial peptide

increases expression

nitrofen results in increased expression of CAMP mRNA

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

G

cyclase associated actin cytoskeleton regulatory protein 2

increases expression

nitrofen results in increased expression of CAP2 mRNA

NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373

G

calpain 15

decreases expression

nitrofen results in decreased expression of CAPN15 mRNA

NCBI chr10:14,972,807...14,999,411
Ensembl chr10:14,972,800...14,999,508

G

calcyphosine-like

increases expression

nitrofen results in increased expression of CAPSL mRNA

NCBI chr 2:58,394,995...58,425,527
Ensembl chr 2:58,411,424...58,424,980

G

carbonic anhydrase 1

increases expression

nitrofen results in increased expression of CAR1 mRNA

NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208

G

carbonic anhydrase 12

increases expression

nitrofen results in increased expression of CA12 mRNA

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

carbonic anhydrase 14

increases expression

nitrofen results in increased expression of CA14 mRNA

NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693

G

carbonic anhydrase 2

increases expression

nitrofen results in increased expression of CAR2 mRNA

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 3

increases expression

nitrofen results in increased expression of CA3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 7

increases expression

nitrofen results in increased expression of CAR7 mRNA

NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467

G

caspase 3

multiple interactions
increases cleavage

Acetylcysteine inhibits the reaction [nitrofen results in increased cleavage of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

calsequestrin 2

decreases expression

nitrofen results in decreased expression of CASQ2 mRNA

NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267

G

calcium-sensing receptor

increases expression

nitrofen results in increased expression of CASR mRNA; nitrofen results in increased expression of CASR protein

NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811

G

catalase

decreases expression

nitrofen results in decreased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cation channel sperm associated auxiliary subunit gamma

decreases expression

nitrofen results in decreased expression of CATSPERG mRNA

NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559

G

caveolin 1

decreases expression

nitrofen results in decreased expression of CAV1 mRNA; nitrofen results in decreased expression of CAV1 protein

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

Cbl proto-oncogene

decreases expression

nitrofen results in decreased expression of CBL mRNA; nitrofen results in decreased expression of CBL protein

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

G

carbonyl reductase 4

increases expression

nitrofen results in increased expression of CBR4 mRNA

NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712

G

chromobox 2

decreases expression

nitrofen results in decreased expression of CBX2 mRNA

NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383

G

chromobox 6

decreases expression

nitrofen results in decreased expression of CBX6 mRNA

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

G

coiled-coil domain containing 120

decreases expression

nitrofen results in decreased expression of CCDC120 mRNA

NCBI chr X:14,753,594...14,772,745
Ensembl chr X:14,753,696...14,772,743

G

coiled-coil domain containing 126

increases expression

nitrofen results in increased expression of CCDC126 mRNA

NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655

G

coiled-coil domain containing 150

increases expression

nitrofen results in increased expression of CCDC150 mRNA

NCBI chr 9:55,793,544...55,897,341
Ensembl chr 9:55,793,551...55,897,224

G

coiled-coil domain 39 molecular ruler complex subunit

decreases expression

nitrofen results in decreased expression of CCDC39 mRNA

NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350

G

coiled-coil domain containing 60

decreases expression

nitrofen results in decreased expression of CCDC60 mRNA

NCBI chr12:40,314,687...40,480,338
Ensembl chr12:40,314,713...40,480,225

G

coiled-coil domain containing 61

decreases expression

nitrofen results in decreased expression of CCDC61 mRNA

NCBI chr 1:78,537,494...78,557,686
Ensembl chr 1:78,537,494...78,557,686

G

C-C motif chemokine ligand 2

increases expression
multiple interactions

nitrofen results in increased expression of CCL2 mRNA; nitrofen results in increased expression of CCL2 protein
Rosiglitazone inhibits the reaction [nitrofen results in increased expression of CCL2 protein]

PMID:15110079 PMID:22595559 PMID:30418988 PMID:33484710

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 21

decreases expression

nitrofen results in decreased expression of CCL21 mRNA

NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686

G

C-C motif chemokine ligand 9

increases expression

nitrofen results in increased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cellular communication network factor 2

decreases expression
multiple interactions

nitrofen results in decreased expression of CCN2 mRNA; nitrofen results in decreased expression of CCN2 protein
Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 mRNA]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 protein]

PMID:20939759 PMID:21258935 PMID:33484710

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 3

decreases expression

nitrofen results in decreased expression of CCN3 mRNA

NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019

G

cellular communication network factor 4

decreases expression

nitrofen results in decreased expression of CCN4 mRNA

NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248

G

CD27 molecule

decreases expression

nitrofen results in decreased expression of CD27 mRNA

NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592

G

CD3 epsilon subunit of T-cell receptor complex

decreases expression

nitrofen results in decreased expression of CD3E mRNA

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

G

CD3 gamma subunit of T-cell receptor complex

decreases expression

nitrofen results in decreased expression of CD3G mRNA

NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147

G

Cd47 molecule

increases expression

nitrofen results in increased expression of CD47 mRNA; nitrofen results in increased expression of CD47 protein

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

G

CD52 molecule

increases expression

nitrofen results in increased expression of CD52 mRNA

NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348

G

Cd68 molecule

increases expression

nitrofen results in increased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CD8 subunit alpha

decreases expression

nitrofen results in decreased expression of CD8A mRNA

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

G

CD8 subunit beta

decreases expression

nitrofen results in decreased expression of CD8B mRNA

NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553

G

CD99 molecule-like 2

increases expression

nitrofen results in increased expression of CD99L2 mRNA

G

codanin 1

decreases expression

nitrofen results in decreased expression of CDAN1 mRNA

NCBI chr 3:107,675,147...107,689,811
Ensembl chr 3:107,673,645...107,689,773

G

cell division cycle 25B

increases expression

nitrofen results in increased expression of CDC25B mRNA

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cadherin 1

increases expression

nitrofen results in increased expression of CDH1 mRNA

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 13

decreases expression

nitrofen results in decreased expression of CDH13 mRNA

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cadherin 19

decreases expression

nitrofen results in decreased expression of CDH19 mRNA

NCBI chr13:27,935,915...28,047,490
Ensembl chr13:27,936,668...28,019,310

G

cadherin 24

decreases expression

nitrofen results in decreased expression of CDH24 mRNA

NCBI chr15:28,091,578...28,101,330
Ensembl chr15:28,091,637...28,101,340

G

cyclin-dependent kinase 2 associated protein 2

increases expression

nitrofen results in increased expression of CDK2AP2 mRNA

NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137

G

chromatin licensing and DNA replication factor 1

decreases expression

nitrofen results in decreased expression of CDT1 mRNA

NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659

G

CEA cell adhesion molecule 1

increases expression

nitrofen results in increased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

centromere protein K

increases expression

nitrofen results in increased expression of CENPK mRNA

NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706

G

centrosomal protein 126

decreases expression

nitrofen results in decreased expression of CEP126 mRNA

NCBI chr 8:5,200,576...5,267,740
Ensembl chr 8:5,218,509...5,267,467

G

centrosomal protein 41

decreases expression

nitrofen results in decreased expression of CEP41 mRNA

NCBI chr 4:59,271,218...59,312,343
Ensembl chr 4:59,271,218...59,310,668

G

carboxylesterase 1D

increases expression

nitrofen results in increased expression of CES1D mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

complement factor H

increases expression

nitrofen results in increased expression of CFH mRNA

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

G

complement factor H-related 1

increases expression

nitrofen results in increased expression of CFHR1 mRNA

NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592

G

complement factor I

increases expression

nitrofen results in increased expression of CFI mRNA

NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561

G

cholesterol 25-hydroxylase

increases expression

nitrofen results in increased expression of CH25H mRNA

NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

nitrofen results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763

G

chitinase 3 like 1

increases expression

nitrofen results in increased expression of CHI3L1 mRNA

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

cell adhesion molecule L1-like

decreases expression

nitrofen results in decreased expression of CHL1 mRNA

NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265

G

CHM like Rab escort protein

decreases expression

nitrofen results in decreased expression of CHML mRNA

NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862

G

charged multivesicular body protein 4C

decreases expression

nitrofen results in decreased expression of CHMP4C mRNA

NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668

G

cholinergic receptor, muscarinic 2

increases expression

nitrofen results in increased expression of CHRM2 mRNA

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor nicotinic alpha 4 subunit

decreases expression

nitrofen results in decreased expression of CHRNA4 mRNA

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cell death-inducing DFFA-like effector b

increases expression

nitrofen results in increased expression of CIDEB mRNA

NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605

G

CDGSH iron sulfur domain 3

decreases expression

nitrofen results in decreased expression of CISD3 mRNA

NCBI chr10:82,679,345...82,682,376
Ensembl chr10:82,679,196...82,682,550

G

cytokine inducible SH2-containing protein

increases expression

nitrofen results in increased expression of CISH mRNA

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

increases expression

nitrofen results in increased expression of CITED1 mRNA

NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

increases expression

nitrofen results in increased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

chloride voltage-gated channel 2

decreases expression

nitrofen results in decreased expression of CLCN2 protein

NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657

G

chloride voltage-gated channel 3

decreases expression

nitrofen results in decreased expression of CLCN3 protein

NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119

G

chloride voltage-gated channel 7

decreases expression

nitrofen results in decreased expression of CLCN7 mRNA

NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130

G

claudin 1

increases expression

nitrofen results in increased expression of CLDN1 mRNA

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 15

increases expression

nitrofen results in increased expression of CLDN15 mRNA

NCBI chr12:19,698,167...19,708,419
Ensembl chr12:19,698,337...19,706,819

G

claudin 18

increases expression

nitrofen results in increased expression of CLDN18 mRNA

NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351

G

claudin 3

increases expression

nitrofen results in increased expression of CLDN3 mRNA

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

C-type lectin domain family 3, member A

increases expression

nitrofen results in increased expression of CLEC3A mRNA

NCBI chr19:42,404,628...42,412,008
Ensembl chr19:42,404,628...42,412,008

G

C-type lectin domain family 4, member F

increases expression

nitrofen results in increased expression of CLEC4F mRNA

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

chloride intracellular channel 3

increases expression

nitrofen results in increased expression of CLIC3 mRNA

NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018

G

chloride intracellular channel 4

decreases expression

nitrofen results in decreased expression of CLIC4 mRNA

NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452

G

chloride intracellular channel 5

decreases expression

nitrofen results in decreased expression of CLIC5 mRNA

NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427

G

CAP-GLY domain containing linker protein 3

decreases expression

nitrofen results in decreased expression of CLIP3 mRNA

NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

increases expression

nitrofen results in increased expression of CLN3 mRNA

NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434

G

carboxymethylenebutenolidase homolog

increases expression

nitrofen results in increased expression of CMBL mRNA

NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009

G

CKLF-like MARVEL transmembrane domain containing 5

decreases expression

nitrofen results in decreased expression of CMTM5 mRNA

NCBI chr15:28,412,624...28,415,304
Ensembl chr15:28,412,624...28,415,287

G

calponin 1

decreases expression

nitrofen results in decreased expression of CNN1 mRNA

PMID:26720608 PMID:33484710

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

cyclin and CBS domain divalent metal cation transport mediator 2

decreases expression

nitrofen results in decreased expression of CNNM2 mRNA

NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286

G

CCR4-NOT transcription complex, subunit 3

decreases expression

nitrofen results in decreased expression of CNOT3 mRNA

NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167

G

cytochrome c oxidase assembly factor 4 homolog

increases expression

nitrofen results in increased expression of COA4 mRNA

NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174

G

collagen type XV alpha 1 chain

decreases expression

nitrofen results in decreased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type I alpha 1 chain

decreases expression
increases expression

nitrofen results in decreased expression of COL1A1 mRNA
nitrofen results in increased expression of COL1A1 mRNA

PMID:10359170 PMID:11329586

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 5 chain

decreases expression

nitrofen results in decreased expression of COL4A5 mRNA

NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692

G

collectin subfamily member 10

increases expression

nitrofen results in increased expression of COLEC10 mRNA

NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675

G

cytochrome c oxidase subunit 6A2

increases expression

nitrofen results in increased expression of COX6A2 mRNA

NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274

G

cytochrome c oxidase subunit 6B2

increases expression

nitrofen results in increased expression of COX6B2 mRNA

NCBI chr 1:69,094,009...69,095,312

G

ceruloplasmin

increases expression

nitrofen results in increased expression of CP mRNA

NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075

G

C3 and PZP-like, alpha-2-macroglobulin domain containing 8

increases expression

nitrofen results in increased expression of CPAMD8 mRNA

NCBI chr 4:155,332,827...155,413,098
Ensembl chr 4:155,332,827...155,413,117

G

carboxypeptidase B2

increases expression

nitrofen results in increased expression of CPB2 mRNA

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

G

carboxypeptidase M

increases expression

nitrofen results in increased expression of CPM mRNA

NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220

G

carboxypeptidase N subunit 1

increases expression

nitrofen results in increased expression of CPN1 mRNA

NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465

G

carboxypeptidase N subunit 2

increases expression

nitrofen results in increased expression of CPN2 mRNA

NCBI chr11:70,486,054...70,495,937
Ensembl chr11:70,486,057...70,496,472

G

coproporphyrinogen oxidase

increases expression

nitrofen results in increased expression of CPOX mRNA

NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746

G

carbamoyl-phosphate synthase 1

increases expression

nitrofen results in increased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1B

increases expression

nitrofen results in increased expression of CPT1B mRNA

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

cAMP responsive element binding protein 3-like 3

increases expression

nitrofen results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

cellular repressor of E1A-stimulated genes 1

increases expression

nitrofen results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression
multiple interactions

nitrofen results in decreased expression of CRISPLD2 mRNA; nitrofen results in decreased expression of CRISPLD2 protein
Tretinoin inhibits the reaction [nitrofen results in decreased expression of CRISPLD2 mRNA]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of CRISPLD2 protein]

PMID:21069352 PMID:33484710

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

C-reactive protein

increases expression

nitrofen results in increased expression of CRP mRNA

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cartilage associated protein

decreases expression

nitrofen results in decreased expression of CRTAP mRNA

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

C-terminal Src kinase

decreases expression

nitrofen results in decreased expression of CSK mRNA

NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292

G

chondroitin sulfate proteoglycan 4

decreases expression

nitrofen results in decreased expression of CSPG4 mRNA

NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010

G

cysteine and glycine rich protein 3

increases expression

nitrofen results in increased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cystathionine gamma-lyase

increases expression

nitrofen results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin alpha 3

decreases expression

nitrofen results in decreased expression of CTNNA3 mRNA

NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978

G

catenin alpha-like 1

decreases expression

nitrofen results in decreased expression of CTNNAL1 mRNA

NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431

G

cathepsin E

increases expression

nitrofen results in increased expression of CTSE mRNA

NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502

G

cathepsin H

increases expression

nitrofen results in increased expression of CTSH mRNA

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cortexin 1

decreases expression

nitrofen results in decreased expression of CTXN1 mRNA

NCBI chr12:2,610,465...2,612,076

G

CXADR, Ig-like cell adhesion molecule

increases expression

nitrofen results in increased expression of CXADR mRNA

NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046

G

C-X-C motif chemokine ligand 13

increases expression

nitrofen results in increased expression of CXCL13 mRNA

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 17

increases expression

nitrofen results in increased expression of CXCL17 mRNA

NCBI chr 1:80,984,751...80,996,842
Ensembl chr 1:80,984,964...80,996,726

G

C-X-C motif chemokine ligand 2

increases expression

nitrofen results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

cytochrome b-245 beta chain

increases expression

nitrofen results in increased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 26, subfamily b, polypeptide 1

decreases expression

nitrofen results in decreased expression of CYP26B1 mRNA

PMID:17203325 PMID:26720608

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

nitrofen results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily c, polypeptide 22

increases expression

nitrofen results in increased expression of CYP2C22 mRNA

NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738

G

cytochrome P450, family 2, subfamily d, polypeptide 1

increases expression

nitrofen results in increased expression of CYP2D1 mRNA

NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084

G

cytochrome P450, family 2, subfamily d, polypeptide 2

increases expression

nitrofen results in increased expression of CYP2D2 mRNA

NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209

G

cytochrome P450, family 2, subfamily d, polypeptide 5

increases expression

nitrofen results in increased expression of CYP2D5 mRNA

NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

nitrofen results in increased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 4, subfamily a, polypeptide 2

increases expression

nitrofen results in increased expression of CYP4A2 mRNA

NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165

G

cytochrome P450, family 4, subfamily f, polypeptide 1

increases expression

nitrofen results in increased expression of CYP4F1 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

G

cytochrome P450, family 4, subfamily f, polypeptide 39

increases expression

nitrofen results in increased expression of CYP4F39 mRNA

NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181

G

cytochrome P450 family 7 subfamily A member 1

increases expression

nitrofen results in increased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

increases expression

nitrofen results in increased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

cysteinyl leukotriene receptor 1

increases expression

nitrofen results in increased expression of CYSLTR1 mRNA

NCBI chr X:71,661,421...71,690,012
Ensembl chr X:71,663,821...71,690,121

G

diacylglycerol lipase, alpha

decreases expression

nitrofen results in decreased expression of DAGLA mRNA

NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232

G

death-associated protein kinase 2

increases expression

nitrofen results in increased expression of DAPK2 mRNA

NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567

G

doublecortin-like kinase 2

decreases expression

nitrofen results in decreased expression of DCLK2 mRNA

NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250

G

defective in cullin neddylation 1 domain containing 2

increases expression

nitrofen results in increased expression of DCUN1D2 mRNA

NCBI chr16:76,254,433...76,281,139
Ensembl chr16:76,254,413...76,281,146

G

dicarbonyl and L-xylulose reductase

increases expression

nitrofen results in increased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

DNA-damage inducible transcript 3

increases expression

nitrofen results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

nitrofen results in increased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

2,4-dienoyl-CoA reductase 1

increases expression

nitrofen results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

defensin alpha 5

increases expression

nitrofen results in increased expression of DEFA5 mRNA

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

G

defensin beta 13

increases expression

nitrofen results in increased expression of DEFB13 mRNA

NCBI chr16:70,129,400...70,131,509
Ensembl chr16:70,129,625...70,131,473

G

delta(4)-desaturase, sphingolipid 1 like 2

increases expression

nitrofen results in increased expression of DEGS1L2 mRNA

NCBI chr13:92,831,549...92,839,257
Ensembl chr13:92,831,537...92,839,246

G

DEPP autophagy regulator 1

increases expression

nitrofen results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

desmin

decreases expression

nitrofen results in decreased expression of DES mRNA; nitrofen results in decreased expression of DES protein

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

deuterosome assembly protein 1

decreases expression

nitrofen results in decreased expression of DEUP1 mRNA

NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199

G

diacylglycerol O-acyltransferase 2

increases expression

nitrofen results in increased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

diacylglycerol kinase, alpha

decreases expression

nitrofen results in decreased expression of DGKA mRNA

NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110

G

diacylglycerol kinase, gamma

decreases expression

nitrofen results in decreased expression of DGKG mRNA

NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212

G

24-dehydrocholesterol reductase

increases expression

nitrofen results in increased expression of DHCR24 mRNA

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

dehydrogenase/reductase 3

decreases expression

nitrofen results in decreased expression of DHRS3 mRNA

NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417

G

diaphanous-related formin 3

decreases expression

nitrofen results in decreased expression of DIAPH3 mRNA

NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975

G

iodothyronine deiodinase 1

increases expression

nitrofen results in increased expression of DIO1 mRNA

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

dispatched RND transporter family member 1

decreases expression

nitrofen results in decreased expression of DISP1 mRNA; nitrofen results in decreased expression of DISP1 protein

NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702

G

discs large MAGUK scaffold protein 4

decreases expression

nitrofen results in decreased expression of DLG4 mRNA

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

delta like canonical Notch ligand 1

increases expression

nitrofen results in increased expression of DLL1 mRNA

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

G

dematin actin binding protein

decreases expression
increases expression

nitrofen results in decreased expression of DMTN mRNA
nitrofen results in increased expression of DMTN mRNA

PMID:26720608 PMID:33484710

NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601

G

dynein, axonemal, light chain 1

increases expression

nitrofen results in increased expression of DNAL1 mRNA

NCBI chr 6:103,747,801...103,779,015
Ensembl chr 6:103,747,753...103,778,878

G

deoxyribonuclease 1L3

increases expression

nitrofen results in increased expression of DNASE1L3 mRNA

NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317

G

docking protein 1

increases expression

nitrofen results in increased expression of DOK1 mRNA

NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465

G

docking protein 5

increases expression

nitrofen results in increased expression of DOK5 mRNA

NCBI chr 3:159,515,886...159,652,811
Ensembl chr 3:159,515,893...159,652,810

G

DOT1 like histone lysine methyltransferase

decreases expression

nitrofen results in decreased expression of DOT1L mRNA

NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475

G

dipeptidase 1

increases expression

nitrofen results in increased expression of DPEP1 mRNA

NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257

G

double PHD fingers 3

increases expression

nitrofen results in increased expression of DPF3 mRNA

NCBI chr 6:102,841,403...103,125,558
Ensembl chr 6:102,846,029...103,125,493

G

dipeptidylpeptidase 4

increases expression

nitrofen results in increased expression of DPP4 mRNA

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

G

dihydropyrimidinase

increases expression

nitrofen results in increased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

DNA-damage regulated autophagy modulator 1

increases expression

nitrofen results in increased expression of DRAM1 mRNA

NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765

G

DS cell adhesion molecule-like 1

decreases expression

nitrofen results in decreased expression of DSCAML1 mRNA

NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320

G

desmoglein 2

increases expression

nitrofen results in increased expression of DSG2 mRNA

NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156

G

desmoplakin

increases expression

nitrofen results in increased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dual specificity phosphatase 14-like 1

decreases expression

nitrofen results in decreased expression of DUSP14L1 mRNA

NCBI chr 2:138,738,130...138,739,473
Ensembl chr 2:138,738,101...138,739,486

G

dual specificity phosphatase 8

decreases expression

nitrofen results in decreased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

dynein light chain Tctex-type 2B

increases expression

nitrofen results in increased expression of DYNLT2B mRNA

NCBI chr11:68,359,138...68,367,573
Ensembl chr11:68,358,263...68,367,499

G

dual specificity tyrosine phosphorylation regulated kinase 3

decreases expression
increases expression

nitrofen results in decreased expression of DYRK3 mRNA
nitrofen results in increased expression of DYRK3 mRNA

PMID:26720608 PMID:33484710

NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778

G

EBP, cholestenol delta-isomerase

increases expression

nitrofen results in increased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

endothelin 1

multiple interactions
decreases expression
increases expression

Dexamethasone inhibits the reaction [nitrofen results in decreased expression of EDN1 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in decreased expression of EDN1 protein]
nitrofen results in decreased expression of EDN1 mRNA; nitrofen results in decreased expression of EDN1 protein
nitrofen results in increased expression of EDN1 mRNA; nitrofen results in increased expression of EDN1 protein

PMID:9473106 PMID:10693666 PMID:12407540 PMID:15756563

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

endothelin receptor type A

decreases expression
increases expression

nitrofen results in decreased expression of EDNRA mRNA
nitrofen results in increased expression of EDNRA mRNA; nitrofen results in increased expression of EDNRA protein

PMID:9473106 PMID:10693666 PMID:12407540 PMID:19851775

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

G

endothelin receptor type B

increases expression
multiple interactions

nitrofen results in increased expression of EDNRB mRNA; nitrofen results in increased expression of EDNRB protein
Dexamethasone promotes the reaction [nitrofen results in increased expression of EDNRB mRNA]

PMID:10693666 PMID:19851775

NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115

G

eukaryotic translation elongation factor 1 alpha 2

increases expression

nitrofen results in increased expression of EEF1A2 mRNA

NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071

G

ephrin A1

increases expression

nitrofen results in increased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

ephrin B1

decreases expression

nitrofen results in decreased expression of EFNB1 mRNA; nitrofen results in decreased expression of EFNB1 protein

NCBI chr X:64,257,351...64,270,158
Ensembl chr X:64,257,351...64,270,157

G

ephrin B2

increases expression

nitrofen results in increased expression of EFNB2 mRNA; nitrofen results in increased expression of EFNB2 protein

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

epidermal growth factor

decreases expression

nitrofen results in decreased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

EGF-like-domain, multiple 6

increases expression

nitrofen results in increased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

EGF-like-domain, multiple 8

decreases expression

nitrofen results in decreased expression of EGFL8 mRNA

NCBI chr20:4,132,930...4,136,024
Ensembl chr20:4,133,629...4,136,018

G

early growth response 1

decreases expression

nitrofen results in decreased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

increases expression

nitrofen results in increased expression of EHHADH mRNA

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 4E family member 3

decreases expression

nitrofen results in decreased expression of EIF4E3 mRNA

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

elastase, neutrophil expressed

increases expression

nitrofen results in increased expression of ELANE mRNA

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

elastin

decreases expression
increases expression

nitrofen results in decreased expression of ELN mRNA; nitrofen results in decreased expression of ELN protein
nitrofen results in increased expression of ELN mRNA

PMID:10359170 PMID:11329586 PMID:15136996 PMID:33484710

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

ELOVL fatty acid elongase 2

increases expression

nitrofen results in increased expression of ELOVL2 mRNA

NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848

G

embigin

increases expression

nitrofen results in increased expression of EMB mRNA

NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050

G

endomucin

increases expression

nitrofen results in increased expression of EMCN mRNA

NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929

G

elastin microfibril interfacer 1

decreases expression

nitrofen results in decreased expression of EMILIN1 mRNA; nitrofen results in decreased expression of EMILIN1 protein

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

endoglin

decreases expression

nitrofen results in decreased expression of ENG mRNA; nitrofen results in decreased expression of ENG protein

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

enolase 1

decreases expression

nitrofen results in decreased expression of ENO1 mRNA

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases expression

nitrofen results in increased expression of ENPP2 mRNA

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleoside triphosphate diphosphohydrolase 2

decreases expression

nitrofen results in decreased expression of ENTPD2 mRNA

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

endosomal transmembrane epsin interactor 3

decreases expression

nitrofen results in decreased expression of ENTREP3 mRNA

NCBI chr 2:174,588,984...174,595,281
Ensembl chr 2:174,589,337...174,595,281

G

E1A binding protein p300

decreases expression

nitrofen results in decreased expression of EP300 mRNA; nitrofen results in decreased expression of EP300 protein

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

endothelial PAS domain protein 1

decreases expression

nitrofen results in decreased expression of EPAS1 mRNA

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

erythrocyte membrane protein band 4.2

increases expression

nitrofen results in increased expression of EPB42 mRNA

NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932

G

enhancer of polycomb homolog 1

decreases expression

nitrofen results in decreased expression of EPC1 mRNA

NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425

G

Eph receptor A4

increases expression

nitrofen results in increased expression of EPHA4 mRNA

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

G

EPH receptor B4

increases expression

nitrofen results in increased expression of EPHB4 mRNA; nitrofen results in increased expression of EPHB4 protein

NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314

G

epoxide hydrolase 1

increases expression

nitrofen results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 3

increases expression

nitrofen results in increased expression of EPHX3 mRNA

NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122

G

erythropoietin

decreases expression

nitrofen results in decreased expression of EPO mRNA; nitrofen results in decreased expression of EPO protein

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

Ets2 repressor factor

decreases expression

nitrofen results in decreased expression of ERF mRNA

NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388

G

ergosterol biosynthesis 28 homolog

increases expression

nitrofen results in increased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

erythroblast membrane associated protein (Scianna blood group)

increases expression

nitrofen results in increased expression of ERMAP mRNA

NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847

G

estrogen receptor 1

affects binding
multiple interactions

nitrofen binds to ESR1 protein
nitrofen binds to and results in increased activity of ESR1 protein

PMID:15253041 PMID:33049310

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

even-skipped homeobox 1

increases expression

nitrofen results in increased expression of EVX1 mRNA

NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967

G

coagulation factor X

increases expression

nitrofen results in increased expression of F10 mRNA

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

coagulation factor XI

increases expression

nitrofen results in increased expression of F11 mRNA

NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437

G

coagulation factor XII

increases expression

nitrofen results in increased expression of F12 mRNA

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

G

coagulation factor XIII B chain

increases expression

nitrofen results in increased expression of F13B mRNA

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

G

coagulation factor II, thrombin

increases expression

nitrofen results in increased expression of F2 mRNA

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

coagulation factor III, tissue factor

increases expression

nitrofen results in increased expression of F3 mRNA

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor V

increases expression

nitrofen results in increased expression of F5 mRNA

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

G

coagulation factor IX

increases expression

nitrofen results in increased expression of F9 mRNA

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

G

fatty acid binding protein 1

increases expression

nitrofen results in increased expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 3

increases expression

nitrofen results in increased expression of FABP3 mRNA

NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718

G

fatty acid binding protein 4

increases expression

nitrofen results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid binding protein 5

increases expression

nitrofen results in increased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid binding protein 7

increases expression

nitrofen results in increased expression of FABP7 mRNA

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

fumarylacetoacetate hydrolase

increases expression

nitrofen results in increased expression of FAH mRNA

NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505

G

FAM111 trypsin like peptidase A

increases expression

nitrofen results in increased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

family with sequence similarity 135, member A

decreases expression

nitrofen results in decreased expression of FAM135A mRNA

NCBI chr 9:26,420,116...26,500,803
Ensembl chr 9:26,420,528...26,500,717

G

family with sequence similarity 162, member A

increases expression

nitrofen results in increased expression of FAM162A mRNA

NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239

G

family with sequence similarity 193, member A

decreases expression

nitrofen results in decreased expression of FAM193A mRNA

NCBI chr14:76,250,103...76,382,525
Ensembl chr14:76,256,161...76,382,514

G

family with sequence similarity 210, member B

decreases expression

nitrofen results in decreased expression of FAM210B mRNA

NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397

G

FANCD2 opposite strand

increases expression

nitrofen results in increased expression of FANCD2OS mRNA

NCBI chr 4:146,740,863...146,747,547
Ensembl chr 4:146,740,863...146,747,569

G

fatty acid synthase

decreases expression

nitrofen results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

filamin binding LIM protein 1

decreases expression

nitrofen results in decreased expression of FBLIM1 mRNA

NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757

G

fibulin 2

decreases expression

nitrofen results in decreased expression of FBLN2 mRNA

NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948

G

fibrillin 1

decreases expression

nitrofen results in decreased expression of FBN1 mRNA; nitrofen results in decreased expression of FBN1 protein

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

fructose-bisphosphatase 1

increases expression

nitrofen results in increased expression of FBP1 mRNA

NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071

G

fibrosin

decreases expression

nitrofen results in decreased expression of FBRS mRNA

NCBI chr 1:182,090,741...182,104,026
Ensembl chr 1:182,089,844...182,103,828

G

Fc gamma receptor 2A

increases expression

nitrofen results in increased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

FCH and double SH3 domains 1

decreases expression

nitrofen results in decreased expression of FCHSD1 mRNA

NCBI chr18:29,793,899...29,804,533
Ensembl chr18:29,793,899...29,804,466

G

farnesyl diphosphate synthase

increases expression

nitrofen results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

ferrochelatase

increases expression

nitrofen results in increased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

fetuin B

increases expression
multiple interactions

nitrofen results in increased expression of FETUB mRNA
Vitamin D affects the reaction [nitrofen results in increased expression of FETUB mRNA]

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

fibrinogen alpha chain

increases expression

nitrofen results in increased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibrinogen beta chain

increases expression

nitrofen results in increased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

fibroblast growth factor 1

decreases expression

nitrofen results in decreased expression of FGF1 mRNA

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor 10

decreases expression

nitrofen results in decreased expression of FGF10 mRNA

PMID:11404268 PMID:12861530

NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866

G

fibroblast growth factor 12

increases expression

nitrofen results in increased expression of FGF12 mRNA

NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607

G

fibroblast growth factor 18

decreases expression

nitrofen results in decreased expression of FGF18 mRNA; nitrofen results in decreased expression of FGF18 protein

NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818

G

fibroblast growth factor 2

multiple interactions
decreases expression

Dexamethasone inhibits the reaction [nitrofen results in decreased expression of FGF2 mRNA]

PMID:10646786 PMID:10898222

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor 7

decreases expression

nitrofen results in decreased expression of FGF7 mRNA

NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929

G

fibroblast growth factor 9

decreases expression

nitrofen results in decreased expression of FGF9 mRNA; nitrofen results in decreased expression of FGF9 protein

NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309

G

fibroblast growth factor receptor 2

increases expression
decreases expression

nitrofen results in increased expression of FGFR2 mRNA; nitrofen results in increased expression of FGFR2 protein
nitrofen results in decreased expression of FGFR2 mRNA

PMID:20638522 PMID:21994076

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibroblast growth factor receptor 3

increases expression
decreases expression

nitrofen results in increased expression of FGFR3 mRNA
nitrofen results in decreased expression of FGFR3 mRNA
nitrofen results in increased expression of FGFR3 mRNA; nitrofen results in increased expression of FGFR3 protein

PMID:9859898 PMID:20638522 PMID:21994076

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fibroblast growth factor receptor 4

increases expression

nitrofen results in increased expression of FGFR4 mRNA

NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242

G

fibroblast growth factor receptor-like 1

decreases expression

nitrofen results in decreased expression of FGFRL1 mRNA; nitrofen results in decreased expression of FGFRL1 protein

PMID:20938900 PMID:33484710

NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928

G

fibrinogen gamma chain

increases expression

nitrofen results in increased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fibrinogen-like 1

increases expression

nitrofen results in increased expression of FGL1 mRNA

NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093

G

FHF complex subunit HOOK interacting protein 1B

decreases expression

nitrofen results in decreased expression of FHIP1B mRNA

NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408

G

formin homology 2 domain containing 3

decreases expression

nitrofen results in decreased expression of FHOD3 mRNA

NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796

G

fin bud initiation factor homolog

increases expression

nitrofen results in increased expression of FIBIN mRNA

NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676

G

FIC domain protein adenylyltransferase

decreases expression

nitrofen results in decreased expression of FICD mRNA

NCBI chr12:42,889,195...42,894,090
Ensembl chr12:42,889,194...42,894,070

G

fat storage-inducing transmembrane protein 1

increases expression

nitrofen results in increased expression of FITM1 mRNA

NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015

G

filamin A

decreases expression

nitrofen results in decreased expression of FLNA mRNA

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

Fms related receptor tyrosine kinase 1

multiple interactions
decreases expression

Hydrogen inhibits the reaction [nitrofen results in decreased expression of FLT1 mRNA]

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

flavin containing dimethylaniline monoxygenase 3

increases expression

nitrofen results in increased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

flavin containing dimethylaniline monoxygenase 5

increases expression

nitrofen results in increased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

fructosamine 3 kinase

increases expression

nitrofen results in increased expression of FN3K mRNA

NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895

G

formin binding protein 1

decreases expression

nitrofen results in decreased expression of FNBP1 mRNA

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

nitrofen results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box A2

decreases expression
multiple interactions

nitrofen results in decreased expression of FOXA2 mRNA
nitrofen results in decreased expression of FOXA2 mRNA; nitrofen results in decreased expression of FOXA2 protein
Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein]; FOXA2 protein inhibits the reaction [nitrofen results in decreased expression of BCL2 protein]; FOXA2 protein inhibits the reaction [nitrofen results in decreased expression of SCGB1A1 protein]; FOXA2 protein inhibits the reaction [nitrofen results in decreased expression of SFTPC protein]; FOXA2 protein inhibits the reaction [nitrofen results in increased expression of BAX protein]; Vitamin A inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein]; Vitamin E inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein]
Vitamin E inhibits the reaction [nitrofen results in decreased expression of FOXA2 mRNA]

PMID:16490937 PMID:16863852 PMID:31843527

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

G

forkhead box C2

decreases expression

nitrofen results in decreased expression of FOXC2 mRNA

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

G

forkhead box F1

decreases expression

nitrofen results in decreased expression of FOXF1 mRNA; nitrofen results in decreased expression of FOXF1 protein

NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738

G

forkhead box N3

decreases expression

nitrofen results in decreased expression of FOXN3 mRNA

NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401

G

forkhead box Q1

decreases expression

nitrofen results in decreased expression of FOXQ1 mRNA

NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377

G

forkhead box S1

decreases expression

nitrofen results in decreased expression of FOXS1 mRNA

NCBI chr 3:141,397,012...141,398,296
Ensembl chr 3:141,397,016...141,398,281

G

FRA10A associated CGG repeat 1

decreases expression

nitrofen results in decreased expression of FRA10AC1 mRNA

NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210

G

Fraser extracellular matrix complex subunit 1

decreases expression
increases expression

nitrofen results in decreased expression of FRAS1 mRNA; nitrofen results in decreased expression of FRAS1 protein
nitrofen results in increased expression of FRAS1 mRNA

PMID:26519041 PMID:33484710

NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726

G

Fras1 related extracellular matrix 1

decreases expression

nitrofen results in decreased expression of FREM1 mRNA; nitrofen results in decreased expression of FREM1 protein

NCBI chr 5:97,321,266...97,469,523
Ensembl chr 5:97,322,538...97,469,543

G

FRAS1 related extracellular matrix 2

decreases expression

nitrofen results in decreased expression of FREM2 mRNA; nitrofen results in decreased expression of FREM2 protein

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

FRY microtubule binding protein

decreases expression

nitrofen results in decreased expression of FRY mRNA

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

FRY like transcription coactivator

decreases expression

nitrofen results in decreased expression of FRYL mRNA

NCBI chr14:34,956,623...35,189,738
Ensembl chr14:34,956,620...35,190,222

G

follistatin-like 1

decreases expression

nitrofen results in decreased expression of FSTL1 mRNA; nitrofen results in decreased expression of FSTL1 protein

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

frizzled class receptor 1

decreases expression

nitrofen results in decreased expression of FZD1 mRNA

NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

G0/G1switch 2

increases expression

nitrofen results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphatase catalytic subunit 1

decreases expression
increases expression

nitrofen results in decreased expression of G6PC1 mRNA
nitrofen results in increased expression of G6PC1 mRNA

PMID:20638522 PMID:33484710

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

gamma-aminobutyric acid type B receptor subunit 2

increases expression

nitrofen results in increased expression of GABBR2 mRNA

NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104

G

growth arrest and DNA-damage-inducible, alpha

increases expression

nitrofen results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, beta

increases expression

nitrofen results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

growth arrest and DNA-damage-inducible, gamma

increases expression

nitrofen results in increased expression of GADD45G mRNA

PMID:26720608 PMID:33484710

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

growth arrest-specific 2 like 3

decreases expression

nitrofen results in decreased expression of GAS2L3 mRNA

NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411

G

GATA binding protein 1

increases expression

nitrofen results in increased expression of GATA1 mRNA

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

G

GATA binding protein 2

decreases expression

nitrofen results in decreased expression of GATA2 mRNA

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

G

GATA binding protein 4

decreases expression
increases expression

nitrofen results in decreased expression of GATA4 mRNA; nitrofen results in decreased expression of GATA4 protein
nitrofen results in increased expression of GATA4 mRNA

PMID:18280291 PMID:23426975 PMID:33484710

NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636

G

GATA binding protein 6

decreases expression

nitrofen results in decreased expression of GATA6 mRNA; nitrofen results in decreased expression of GATA6 protein

PMID:17270562 PMID:18280291 PMID:29196881

NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532

G

guanylate binding protein 2

increases expression

nitrofen results in increased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

GC, vitamin D binding protein

increases expression
multiple interactions

nitrofen results in increased expression of GC mRNA
Vitamin D affects the reaction [nitrofen results in increased expression of GC mRNA]

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

GTP cyclohydrolase I feedback regulator

increases expression

nitrofen results in increased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glucosaminyl (N-acetyl) transferase 2

decreases expression

nitrofen results in decreased expression of GCNT2 mRNA

NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611

G

guanine deaminase

increases expression

nitrofen results in increased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

growth differentiation factor 6

increases expression

nitrofen results in increased expression of GDF6 mRNA

NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567

G

glial cell derived neurotrophic factor

decreases expression
increases expression

nitrofen results in decreased expression of GDNF mRNA; nitrofen results in decreased expression of GDNF protein
nitrofen results in increased expression of GDNF mRNA; nitrofen results in increased expression of GDNF protein

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

guided entry of tail-anchored proteins factor 3, ATPase

decreases expression

nitrofen results in decreased expression of GET3 mRNA

NCBI chr19:23,130,109...23,138,196
Ensembl chr19:23,130,109...23,138,193

G

GDNF family receptor alpha 3

decreases expression

nitrofen results in decreased expression of GFRA3 mRNA

NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105

G

gap junction protein, alpha 1

increases expression
multiple interactions
decreases expression
affects expression

nitrofen results in increased expression of GJA1 mRNA
Tretinoin inhibits the reaction [nitrofen results in decreased expression of GJA1 mRNA]; Vitamin A inhibits the reaction [nitrofen results in increased expression of GJA1 mRNA]
nitrofen affects the expression of GJA1 protein

PMID:16292552 PMID:16720372 PMID:22325386

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, beta 1

increases expression

nitrofen results in increased expression of GJB1 mRNA

NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925

G

GLI family zinc finger 2

decreases expression

nitrofen results in decreased expression of GLI2 mRNA

NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574

G

glyoxalase domain containing 5

increases expression

nitrofen results in increased expression of GLOD5 mRNA

NCBI chr X:14,473,994...14,488,797
Ensembl chr X:14,473,994...14,488,683

G

glucagon-like peptide 1 receptor

multiple interactions
decreases expression

Dexamethasone inhibits the reaction [nitrofen results in decreased expression of GLP1R mRNA]; Liraglutide inhibits the reaction [nitrofen results in decreased expression of GLP1R mRNA]

PMID:23354098 PMID:33484710

NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241

G

glutaredoxin 5

increases expression

nitrofen results in increased expression of GLRX5 mRNA

NCBI chr 6:123,988,461...123,998,545
Ensembl chr 6:123,988,134...123,998,545

G

glycolipid transfer protein domain containing 2

increases expression

nitrofen results in increased expression of GLTPD2 mRNA

NCBI chr10:55,233,563...55,236,125
Ensembl chr10:55,233,571...55,235,233

G

glutamate dehydrogenase 1

increases expression

nitrofen results in increased expression of GLUD1 mRNA

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

glutamate-ammonia ligase

increases expression

nitrofen results in increased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

G protein subunit alpha 14

decreases expression

nitrofen results in decreased expression of GNA14 mRNA

NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423

G

G protein subunit alpha z

decreases expression

nitrofen results in decreased expression of GNAZ mRNA

NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907

G

glycine N-methyltransferase

increases expression

nitrofen results in increased expression of GNMT mRNA

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

glutamic-oxaloacetic transaminase 1

increases expression

nitrofen results in increased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glutamic-oxaloacetic transaminase 2

increases expression

nitrofen results in increased expression of GOT2 mRNA

NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994

G

glycoprotein Ib platelet subunit beta

decreases expression

nitrofen results in decreased expression of GP1BB mRNA

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

G

glycerol-3-phosphate acyltransferase 3

decreases expression

nitrofen results in decreased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

glycerol-3-phosphate dehydrogenase 1

increases expression

nitrofen results in increased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

glycoprotein nmb

decreases expression

nitrofen results in decreased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor 155

decreases expression

nitrofen results in decreased expression of GPR155 mRNA

NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275

G

G protein-coupled receptor 161

decreases expression

nitrofen results in decreased expression of GPR161 mRNA

NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613

G

G protein-coupled receptor 174

decreases expression

nitrofen results in decreased expression of GPR174 mRNA

NCBI chr X:72,355,452...72,396,146
Ensembl chr X:72,355,033...72,397,658

G

G protein-coupled receptor 182

increases expression

nitrofen results in increased expression of GPR182 mRNA

NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210

G

G protein-coupled receptor 21

decreases expression

nitrofen results in decreased expression of GPR21 mRNA

NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930

G

G protein-coupled receptor, class C, group 5, member C

increases expression

nitrofen results in increased expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

glutathione peroxidase 1

increases expression

nitrofen results in increased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

GREB1 like retinoic acid receptor coactivator

decreases expression

nitrofen results in decreased expression of GREB1L mRNA

NCBI chr18:1,392,330...1,629,483
Ensembl chr18:1,392,725...1,628,067

G

gremlin 1, DAN family BMP antagonist

decreases expression

nitrofen results in decreased expression of GREM1 mRNA

NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082

G

gremlin 2, DAN family BMP antagonist

decreases expression

nitrofen results in decreased expression of GREM2 mRNA

NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615

G

glyoxylate and hydroxypyruvate reductase

increases expression

nitrofen results in increased expression of GRHPR mRNA

NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603

G

glutamate ionotropic receptor AMPA type subunit 1

decreases expression

nitrofen results in decreased expression of GRIA1 mRNA

NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283

G

G protein-coupled receptor kinase 3

decreases expression

nitrofen results in decreased expression of GRK3 mRNA

NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262

G

glutathione S-transferase alpha 1

increases expression

nitrofen results in increased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 3

increases expression

nitrofen results in increased expression of GSTA3 mRNA

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 4

increases expression

nitrofen results in increased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase kappa 1

increases expression

nitrofen results in increased expression of GSTK1 mRNA

NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase mu 1

increases expression

nitrofen results in increased expression of GSTM1 mRNA

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase zeta 1

increases expression

nitrofen results in increased expression of GSTZ1 mRNA

NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284

G

glycophorin A

increases expression

nitrofen results in increased expression of GYPA mRNA

NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822

G

glycogen synthase 2

increases expression

nitrofen results in increased expression of GYS2 mRNA

NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228

G

H2A clustered histone 1

increases expression

nitrofen results in increased expression of H2AC1 mRNA

NCBI chr17:41,171,324...41,171,801
Ensembl chr17:41,135,489...41,172,022

G

3-hydroxyanthranilate 3,4-dioxygenase

increases expression

nitrofen results in increased expression of HAAO mRNA

NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877

G

hyaluronan binding protein 2

increases expression

nitrofen results in increased expression of HABP2 mRNA

NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160

G

hydroxyacyl-CoA dehydrogenase

increases expression

nitrofen results in increased expression of HADH mRNA

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

G

hydroxyacyl glutathione hydrolase

increases expression

nitrofen results in increased expression of HAGH mRNA

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

hepcidin antimicrobial peptide

increases expression
multiple interactions

nitrofen results in increased expression of HAMP mRNA
Vitamin D affects the reaction [nitrofen results in increased expression of HAMP mRNA]

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hepatitis A virus cellular receptor 1

increases expression

nitrofen results in increased expression of HAVCR1 mRNA

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

hemoglobin alpha, adult chain 3

decreases expression

nitrofen results in decreased expression of HBA-A3 mRNA

NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481

G

hemoglobin subunit epsilon 1

increases expression

nitrofen results in increased expression of HBE1 mRNA

NCBI chr 1:158,282,931...158,458,855
Ensembl chr 1:158,282,936...158,284,391

G

heparin-binding EGF-like growth factor

decreases expression

nitrofen results in decreased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

hemoglobin subunit zeta

increases expression

nitrofen results in increased expression of HBZ mRNA

NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312

G

hematopoietic cell signal transducer

increases expression

nitrofen results in increased expression of HCST mRNA

NCBI chr 1:85,676,976...85,679,083
Ensembl chr 1:85,676,979...85,679,012

G

histidine decarboxylase

increases expression

nitrofen results in increased expression of HDC mRNA

NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341

G

hemogen

increases expression

nitrofen results in increased expression of HEMGN mRNA

NCBI chr 5:60,679,633...60,698,597
Ensembl chr 5:60,679,633...60,698,669

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

nitrofen results in increased expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 1

increases expression

nitrofen results in increased expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes-related family bHLH transcription factor with YRPW motif-like

decreases expression

nitrofen results in decreased expression of HEYL mRNA

NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152

G

homogentisate 1, 2-dioxygenase

increases expression

nitrofen results in increased expression of HGD mRNA

NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323

G

hepatocyte growth factor

decreases expression

nitrofen results in decreased expression of HGF mRNA; nitrofen results in decreased expression of HGF protein

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

HGF activator

increases expression

nitrofen results in increased expression of HGFAC mRNA

NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278

G

huntingtin interacting protein 1

decreases expression

nitrofen results in decreased expression of HIP1 mRNA

NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725

G

hexokinase 1

decreases expression

nitrofen results in decreased expression of HK1 mRNA

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

G

hydroxymethylbilane synthase

increases expression

nitrofen results in increased expression of HMBS mRNA

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression

nitrofen results in increased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

nitrofen results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

increases expression

nitrofen results in increased expression of HNF4A mRNA

PMID:26720608 PMID:33484710

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

G

HOP homeobox

multiple interactions

[nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of HOPX mRNA; [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of HOPX protein

NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909

G

homeobox A1

multiple interactions

nitrofen inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]

NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504

G

homeobox A3

decreases expression

nitrofen results in decreased expression of HOXA3 mRNA

NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218

G

homeo box A5

increases expression

nitrofen results in increased expression of HOXA5 mRNA

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

G

homeo box B3

increases expression

nitrofen results in increased expression of HOXB3 mRNA

NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107

G

homeo box B5

affects expression

nitrofen affects the expression of HOXB5 protein

NCBI chr10:81,269,372...81,271,580
Ensembl chr10:81,269,372...81,271,580

G

haptoglobin

increases expression

nitrofen results in increased expression of HP mRNA

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

4-hydroxyphenylpyruvate dioxygenase

increases expression

nitrofen results in increased expression of HPD mRNA

NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766

G

HPS4, biogenesis of lysosomal organelles complex 3 subunit 2

decreases expression

nitrofen results in decreased expression of HPS4 mRNA

NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632

G

hemopexin

increases expression

nitrofen results in increased expression of HPX mRNA

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

G

histidine-rich glycoprotein

increases expression

nitrofen results in increased expression of HRG mRNA

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

G

heparan sulfate-glucosamine 3-sulfotransferase 3A1

increases expression

nitrofen results in increased expression of HS3ST3A1 mRNA

NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

nitrofen results in increased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

heat shock protein family B (small) member 3

increases expression

nitrofen results in increased expression of HSPB3 mRNA

NCBI chr 2:45,295,285...45,295,999
Ensembl chr 2:45,295,053...45,296,145

G

5-hydroxytryptamine receptor 1B

decreases expression

nitrofen results in decreased expression of HTR1B mRNA

NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549

G

5-hydroxytryptamine receptor 2A

increases expression

nitrofen results in increased expression of HTR2A mRNA; nitrofen results in increased expression of HTR2A protein

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

HtrA serine peptidase 4

decreases expression

nitrofen results in decreased expression of HTRA4 mRNA

NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074

G

hypoxia up-regulated 1

decreases expression

nitrofen results in decreased expression of HYOU1 mRNA

NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186

G

intercellular adhesion molecule 1

decreases expression
multiple interactions
increases expression

nitrofen results in decreased expression of ICAM1 mRNA; nitrofen results in decreased expression of ICAM1 protein
Dexamethasone inhibits the reaction [nitrofen results in increased expression of ICAM1 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in increased expression of ICAM1 protein]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of ICAM1 mRNA]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of ICAM1 protein]
nitrofen results in increased expression of ICAM1 mRNA; nitrofen results in increased expression of ICAM1 protein

PMID:12759764 PMID:17245593 PMID:18280292

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 2

multiple interactions

[nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

inhibitor of DNA binding 4

increases expression

nitrofen results in increased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

interferon induced with helicase C domain 1

decreases expression

nitrofen results in decreased expression of IFIH1 mRNA

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon induced transmembrane protein 1

increases expression

nitrofen results in increased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

insulin-like growth factor 1

multiple interactions
increases expression
decreases expression

Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 protein]
nitrofen results in increased expression of IGF1 mRNA; nitrofen results in increased expression of IGF1 protein
nitrofen results in decreased expression of IGF1 mRNA

PMID:10370016 PMID:11409163

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

decreases expression
multiple interactions

nitrofen results in decreased expression of IGF1R mRNA; nitrofen results in decreased expression of IGF1R protein
Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R mRNA]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R protein]

PMID:20620343 PMID:21433279

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2

multiple interactions
decreases expression
increases expression

Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF2 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF2 protein]; Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF2 protein]
nitrofen results in increased expression of IGF2 mRNA; nitrofen results in increased expression of IGF2 protein

PMID:10370016 PMID:24352370

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

G

insulin-like growth factor 2 receptor

decreases expression
multiple interactions

nitrofen results in decreased expression of IGF2R mRNA; nitrofen results in decreased expression of IGF2R protein
Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF2R mRNA]

PMID:20620343 PMID:21433279

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein 1

increases expression

nitrofen results in increased expression of IGFBP1 mRNA

PMID:27592368 PMID:33484710

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

increases expression

nitrofen results in increased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 3

decreases expression

nitrofen results in decreased expression of IGFBP3 mRNA; nitrofen results in decreased expression of IGFBP3 protein

PMID:19844724 PMID:33484710

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 4

increases expression

nitrofen results in increased expression of IGFBP4 mRNA; nitrofen results in increased expression of IGFBP4 protein

NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225

G

insulin-like growth factor binding protein 5

decreases expression

nitrofen results in decreased expression of IGFBP5 mRNA; nitrofen results in decreased expression of IGFBP5 protein

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

immunoglobulin heavy constant gamma 1

increases expression

nitrofen results in increased expression of IGHG1 mRNA

Ensembl chr 6:132,389,370...132,393,397

G

immunoglobulin superfamily, member 5

increases expression

nitrofen results in increased expression of IGSF5 mRNA

NCBI chr11:35,686,513...35,729,396
Ensembl chr11:35,686,705...35,741,129

G

immunoglobulin superfamily, member 9B

decreases expression

nitrofen results in decreased expression of IGSF9B mRNA

NCBI chr 8:25,712,644...25,769,481
Ensembl chr 8:25,712,644...25,758,554

G

IKAROS family zinc finger 2

decreases expression

nitrofen results in decreased expression of IKZF2 mRNA

NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867

G

interleukin 18

increases expression

nitrofen results in increased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

increases expression

nitrofen results in increased expression of IL1A mRNA

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 6

increases expression

nitrofen results in increased expression of IL6 mRNA; nitrofen results in increased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inverted formin 2

decreases expression

nitrofen results in decreased expression of INF2 mRNA

NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941

G

inhibin subunit alpha

decreases expression

nitrofen results in decreased expression of INHA mRNA

NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248

G

inhibin subunit beta A

decreases expression

nitrofen results in decreased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inhibin subunit beta E

increases expression

nitrofen results in increased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

inhibitor of carbonic anhydrase

increases expression

nitrofen results in increased expression of INHCA mRNA

NCBI chr 8:103,836,846...103,874,980
Ensembl chr 8:103,823,196...103,874,985

G

insulin induced gene 1

increases expression

nitrofen results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

insulin receptor

decreases expression
multiple interactions

nitrofen results in decreased expression of INSR mRNA; nitrofen results in decreased expression of INSR protein
Tretinoin inhibits the reaction [nitrofen results in decreased expression of INSR mRNA]

PMID:20438933 PMID:21433279

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

G

inositol 1,4,5-triphosphate receptor associated 1

decreases expression

nitrofen results in decreased expression of IRAG1 mRNA

NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176

G

iroquois homeobox 1

increases expression

nitrofen results in increased expression of IRX1 mRNA; nitrofen results in increased expression of IRX1 protein

NCBI chr 1:31,294,615...31,300,444
Ensembl chr 1:31,294,615...31,300,444

G

iroquois homeobox 2

increases expression

nitrofen results in increased expression of IRX2 mRNA; nitrofen results in increased expression of IRX2 protein

NCBI chr 1:30,660,960...30,666,378
Ensembl chr 1:30,660,960...30,666,378

G

iroquois homeobox 3

increases expression

nitrofen results in increased expression of IRX3 mRNA; nitrofen results in increased expression of IRX3 protein

NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317

G

iroquois homeobox 5

increases expression

nitrofen results in increased expression of IRX5 mRNA; nitrofen results in increased expression of IRX5 protein

NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318

G

iron-sulfur cluster assembly 1

increases expression

nitrofen results in increased expression of ISCA1 mRNA

NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955

G

integrin subunit alpha 3

decreases expression

nitrofen results in decreased expression of ITGA3 mRNA; nitrofen results in decreased expression of ITGA3 protein

NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118

G

integrin subunit alpha 4

decreases expression

nitrofen results in decreased expression of ITGA4 mRNA

NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715

G

integrin subunit alpha 5

increases expression

nitrofen results in increased expression of ITGA5 protein

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit alpha 6

decreases expression

nitrofen results in decreased expression of ITGA6 mRNA; nitrofen results in decreased expression of ITGA6 protein

PMID:20638522 PMID:28701000

NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428

G

integrin subunit alpha 8

decreases expression

nitrofen results in decreased expression of ITGA8 mRNA; nitrofen results in decreased expression of ITGA8 protein

PMID:28701000 PMID:33484710

NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510

G

integrin subunit alpha V

increases expression

nitrofen results in increased expression of ITGAV protein

NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639

G

integrin subunit beta 4

decreases expression

nitrofen results in decreased expression of ITGB4 mRNA

NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012

G

inter-alpha trypsin inhibitor, heavy chain 1

increases expression

nitrofen results in increased expression of ITIH1 mRNA

NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363

G

inter-alpha trypsin inhibitor, heavy chain 3

increases expression

nitrofen results in increased expression of ITIH3 mRNA

NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924

G

inter-alpha-trypsin inhibitor heavy chain 4

increases expression

nitrofen results in increased expression of ITIH4 mRNA

NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708

G

inositol-trisphosphate 3-kinase B

decreases expression

nitrofen results in decreased expression of ITPKB mRNA

NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004

G

junctional cadherin 5 associated

decreases expression

nitrofen results in decreased expression of JCAD mRNA

NCBI chr17:53,089,382...53,130,996
Ensembl chr17:53,089,382...53,130,967

G

kalirin, RhoGEF kinase

decreases expression

nitrofen results in decreased expression of KALRN mRNA

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

G

KN motif and ankyrin repeat domains 4

decreases expression

nitrofen results in decreased expression of KANK4 mRNA

NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555

G

potassium voltage-gated channel subfamily A member 2

multiple interactions
decreases expression

Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNA2 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNA2 protein]
nitrofen results in decreased expression of KCNA2 mRNA; nitrofen results in decreased expression of KCNA2 protein

NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400

G

potassium voltage-gated channel subfamily A member 5

decreases expression

nitrofen results in decreased expression of KCNA5 mRNA; nitrofen results in decreased expression of KCNA5 protein

NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697

G

potassium voltage-gated channel subfamily B member 1

multiple interactions
decreases expression

Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNB1 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNB1 protein]
nitrofen results in decreased expression of KCNB1 mRNA; nitrofen results in decreased expression of KCNB1 protein

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

G

potassium voltage-gated channel subfamily C member 3

decreases expression

nitrofen results in decreased expression of KCNC3 mRNA

NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160

G

potassium voltage-gated channel subfamily D member 3

decreases expression

nitrofen results in decreased expression of KCND3 mRNA

NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345

G

potassium voltage-gated channel subfamily E regulatory subunit 1

increases expression

nitrofen results in increased expression of KCNE1 mRNA

NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901

G

potassium voltage-gated channel subfamily E regulatory subunit 4

decreases expression

nitrofen results in decreased expression of KCNE4 mRNA

NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979

G

potassium voltage-gated channel subfamily H member 7

increases expression

nitrofen results in increased expression of KCNH7 mRNA

NCBI chr 3:47,329,338...47,822,122
Ensembl chr 3:47,338,501...47,822,195

G

potassium inwardly-rectifying channel, subfamily J, member 15

decreases expression
increases expression

nitrofen results in decreased expression of KCNJ15 mRNA
nitrofen results in increased expression of KCNJ15 mRNA

PMID:20638522 PMID:33484710

NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952

G

potassium inwardly-rectifying channel, subfamily J, member 3

increases expression

nitrofen results in increased expression of KCNJ3 mRNA

NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124

G

potassium inwardly-rectifying channel, subfamily J, member 8

decreases expression

nitrofen results in decreased expression of KCNJ8 mRNA; nitrofen results in decreased expression of KCNJ8 protein

NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603

G

potassium two pore domain channel subfamily K member 1

increases expression

nitrofen results in increased expression of KCNK1 mRNA

NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724

G

potassium two pore domain channel subfamily K member 6

decreases expression

nitrofen results in decreased expression of KCNK6 mRNA

NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677

G

potassium calcium-activated channel subfamily M alpha 1

decreases expression
multiple interactions

nitrofen results in decreased expression of KCNMA1 mRNA; nitrofen results in decreased expression of KCNMA1 protein
Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 protein]

PMID:15088113 PMID:33484710

NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198

G

potassium calcium-activated channel subfamily M regulatory beta subunit 1

decreases expression

nitrofen results in decreased expression of KCNMB1 mRNA

NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798

G

potassium voltage-gated channel subfamily Q member 5

decreases expression

nitrofen results in decreased expression of KCNQ5 mRNA; nitrofen results in decreased expression of KCNQ5 protein

NCBI chr 9:23,830,185...24,395,984
Ensembl chr 9:23,833,087...24,394,704

G

potassium sodium-activated channel subfamily T member 2

decreases expression

nitrofen results in decreased expression of KCNT2 mRNA

NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987

G

kinase insert domain receptor

multiple interactions
decreases expression

Hydrogen inhibits the reaction [nitrofen results in decreased expression of KDR mRNA]

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

Kell metallo-endopeptidase (Kell blood group)

increases expression

nitrofen results in increased expression of KEL mRNA

NCBI chr 4:70,568,241...70,585,666
Ensembl chr 4:70,568,243...70,585,631

G

KIAA1549 homolog

decreases expression

nitrofen results in decreased expression of KIAA1549 mRNA

NCBI chr 4:66,840,674...66,968,407
Ensembl chr 4:66,760,162...66,968,436

G

kinesin family member 28

increases expression

nitrofen results in increased expression of KIF28P mRNA

NCBI chr13:91,427,527...91,482,297
Ensembl chr13:91,427,736...91,482,237

G

kinesin family member 7

decreases expression

nitrofen results in decreased expression of KIF7 mRNA; nitrofen results in decreased expression of KIF7 protein

NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576

G

kirre like nephrin family adhesion molecule 1

decreases expression

nitrofen results in decreased expression of KIRREL1 mRNA

NCBI chr 2:172,521,644...172,615,057
Ensembl chr 2:172,525,245...172,615,299

G

KIT proto-oncogene receptor tyrosine kinase

increases expression

nitrofen results in increased expression of KIT mRNA; nitrofen results in increased expression of KIT protein

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

KIT ligand

increases expression

nitrofen results in increased expression of KITLG mRNA; nitrofen results in increased expression of KITLG protein

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

KLF transcription factor 1

increases expression

nitrofen results in increased expression of KLF1 mRNA

NCBI chr19:23,250,627...23,253,802
Ensembl chr19:23,250,631...23,253,758

G

KLF transcription factor 12

decreases expression

nitrofen results in decreased expression of KLF12 mRNA

NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056

G

KLF transcription factor 2

decreases expression

nitrofen results in decreased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

kelch domain containing 8A

increases expression

nitrofen results in increased expression of KLHDC8A mRNA

NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277

G

kelch-like family member 31

decreases expression

nitrofen results in decreased expression of KLHL31 mRNA

NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873

G

kelch-like family member 41

increases expression

nitrofen results in increased expression of KLHL41 mRNA

NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222

G

kallikrein B1

increases expression

nitrofen results in increased expression of KLKB1 mRNA

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

G

kynurenine 3-monooxygenase

increases expression

nitrofen results in increased expression of KMO mRNA

NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881

G

kininogen 1

increases expression

nitrofen results in increased expression of KNG1 mRNA

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

G

kininogen 2-like 1

increases expression

nitrofen results in increased expression of KNG2L1 mRNA

NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971

G

keratin 18

increases expression

nitrofen results in increased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166

G

keratin 8

increases expression

nitrofen results in increased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

L1 cell adhesion molecule

decreases expression

nitrofen results in decreased expression of L1CAM mRNA

NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857

G

laminin subunit alpha 5

decreases expression

nitrofen results in decreased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 1

decreases expression

nitrofen results in decreased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

lysosomal-associated membrane protein 3

increases expression

nitrofen results in increased expression of LAMP3 mRNA

NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784

G

lipocalin 2

increases expression
decreases expression

nitrofen results in increased expression of LCN2 mRNA; nitrofen results in increased expression of LCN2 protein
nitrofen results in decreased expression of LCN2 mRNA

PMID:23114405 PMID:27592368 PMID:33484710

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

low density lipoprotein receptor class A domain containing 4

decreases expression

nitrofen results in decreased expression of LDLRAD4 mRNA

NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238

G

leukocyte cell-derived chemotaxin 2

increases expression

nitrofen results in increased expression of LECT2 mRNA

NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983

G

lymphoid enhancer binding factor 1

decreases expression

nitrofen results in decreased expression of LEF1 mRNA

PMID:26720608 PMID:33484710

NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794

G

galectin 2

increases expression

nitrofen results in increased expression of LGALS2 mRNA

NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802

G

galectin 5

increases expression

nitrofen results in increased expression of LGALS5 mRNA

NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153

G

galectin 9

increases expression

nitrofen results in increased expression of LGALS9 mRNA

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

G

leucine-rich, glioma inactivated 1

decreases expression

nitrofen results in decreased expression of LGI1 mRNA

NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616

G

leucine-rich repeat LGI family, member 3

increases expression

nitrofen results in increased expression of LGI3 mRNA

NCBI chr15:45,605,611...45,612,739
Ensembl chr15:45,605,611...45,612,739

G

leucine-rich repeat LGI family, member 4

decreases expression

nitrofen results in decreased expression of LGI4 mRNA

NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874

G

leucine-rich repeat-containing G protein-coupled receptor 6

decreases expression

nitrofen results in decreased expression of LGR6 mRNA

NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945

G

leucine rich repeat and Ig domain containing 1

decreases expression

nitrofen results in decreased expression of LINGO1 mRNA

NCBI chr 8:57,011,272...57,193,496
Ensembl chr 8:57,010,007...57,196,544

G

lipase C, hepatic type

increases expression

nitrofen results in increased expression of LIPC mRNA

NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464

G

LIM and cysteine-rich domains 1

decreases expression

nitrofen results in decreased expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

leiomodin 2

increases expression

nitrofen results in increased expression of LMOD2 mRNA

NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120

G

lysyl oxidase

decreases expression

nitrofen results in decreased expression of LOX mRNA; nitrofen results in decreased expression of LOX protein

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

lysophosphatidylcholine acyltransferase 4

decreases expression

nitrofen results in decreased expression of LPCAT4 mRNA

NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875

G

lipin 1

increases expression

nitrofen results in increased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

lecithin retinol acyltransferase

decreases expression
increases expression

nitrofen results in decreased expression of LRAT mRNA
nitrofen results in increased expression of LRAT mRNA; nitrofen results in increased expression of LRAT protein

PMID:17203325 PMID:24972641 PMID:26720608 PMID:33484710

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

leucine-rich repeat-containing 10

increases expression

nitrofen results in increased expression of LRRC10 mRNA

NCBI chr 7:52,686,972...52,688,369
Ensembl chr 7:52,686,972...52,688,369

G

leucine rich repeat containing 23

decreases expression

nitrofen results in decreased expression of LRRC23 mRNA

NCBI chr 4:157,581,285...157,592,188
Ensembl chr 4:157,581,291...157,591,860

G

leucine rich repeat containing 7

decreases expression

nitrofen results in decreased expression of LRRC7 mRNA

NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547

G

leucine rich repeat containing 9

decreases expression

nitrofen results in decreased expression of LRRC9 mRNA

NCBI chr 6:91,017,739...91,095,847
Ensembl chr 6:91,017,736...91,100,237

G

leucine rich repeat neuronal 1

decreases expression

nitrofen results in decreased expression of LRRN1 mRNA

NCBI chr 4:140,476,752...140,520,210
Ensembl chr 4:140,476,324...140,518,620

G

latent transforming growth factor beta binding protein 2

decreases expression

nitrofen results in decreased expression of LTBP2 mRNA

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

leucine rich adaptor protein 1

decreases expression

nitrofen results in decreased expression of LURAP1 mRNA

NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766

G

lysozyme 2

increases expression

nitrofen results in increased expression of LYZ2 mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

leucine zipper tumor suppressor 2

decreases expression

nitrofen results in decreased expression of LZTS2 mRNA

NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423

G

MAF bZIP transcription factor K

decreases expression

nitrofen results in decreased expression of MAFK mRNA

NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048

G

mal, T-cell differentiation protein

decreases expression

nitrofen results in decreased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mastermind-like transcriptional coactivator 1

decreases expression

nitrofen results in decreased expression of MAML1 mRNA

NCBI chr10:34,588,639...34,623,024
Ensembl chr10:34,588,646...34,623,338

G

microtubule-associated protein 2

decreases expression

nitrofen results in decreased expression of MAP2 mRNA

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase kinase 12

decreases expression

nitrofen results in decreased expression of MAP3K12 mRNA

NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789

G

MARVEL domain containing 2

increases expression

nitrofen results in increased expression of MARVELD2 mRNA

NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150

G

MBL associated serine protease 1

increases expression

nitrofen results in increased expression of MASP1 mRNA

PMID:26720608 PMID:33484710

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

G

MBL associated serine protease 2

increases expression

nitrofen results in increased expression of MASP2 mRNA

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

G

microtubule associated serine/threonine kinase family member 4

decreases expression

nitrofen results in decreased expression of MAST4 mRNA

NCBI chr 2:33,893,241...34,483,682
Ensembl chr 2:33,894,436...34,483,723

G

methionine adenosyltransferase 1A

increases expression

nitrofen results in increased expression of MAT1A mRNA

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

mannose binding lectin 2

increases expression

nitrofen results in increased expression of MBL2 mRNA

NCBI chr 1:228,016,439...228,024,736

G

myelin basic protein

decreases expression

nitrofen results in decreased expression of MBP mRNA

NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404

G

melanoma cell adhesion molecule

decreases expression

nitrofen results in decreased expression of MCAM mRNA

NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571

G

myocyte enhancer factor 2C

decreases expression

nitrofen results in decreased expression of MEF2C mRNA

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

G

myocyte enhancer factor 2D

decreases expression