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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
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Accession:CHEBI:76838 term browser browse the term
Definition:An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
Synonyms:related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* inhibitor;   EC 1.14.14.* inhibitors


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1-aminobenzotriazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-Coenzyme A acetyltransferase 1 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of ACAT1 protein] CTD PMID:32435916 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Chlorpyrifos metabolite results in decreased activity of ACHE protein] CTD PMID:30625376 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ACOT2 protein] CTD PMID:32435916 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ALDH1B1 protein] CTD PMID:32435916 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CAR3 protein] CTD PMID:32435916 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583 		JBrowse link
G Cd86 CD86 antigen multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CD86 protein] CTD PMID:21742781 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Ces3a carboxylesterase 3A multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CES3A protein] CTD PMID:32435916 NCBI chr 8:105,775,208...105,788,560
Ensembl chr 8:105,775,233...105,785,045 		JBrowse link
G Ces3b carboxylesterase 3B multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CES3B protein] CTD PMID:32435916 NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO 1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]
1-aminobenzotriazole results in increased expression of CYP1A1 protein
1-aminobenzotriazole inhibits the reaction [Oxygen results in increased activity of CYP1A1 protein]; [1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A1 protein		 CTD PMID:10640292 PMID:20187624 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity		 ISO [1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A2 protein; [Oxygen co-treated with 1-aminobenzotriazole] results in increased expression of CYP1A2 protein
1-aminobenzotriazole results in increased expression of CYP1A2 protein
1-aminobenzotriazole results in decreased activity of CYP1A2 protein		 CTD PMID:10640292 PMID:15618748 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases activity
multiple interactions		 ISO 1-aminobenzotriazole results in decreased activity of CYP2C9 protein
1-aminobenzotriazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]		 CTD PMID:11375247 PMID:15618748 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions
decreases activity		 ISO 1-aminobenzotriazole inhibits the reaction [CYP2D6 protein results in increased hydroxylation of bufuralol]
1-aminobenzotriazole results in decreased activity of CYP2D6 protein		 CTD PMID:11375247 PMID:15618748 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity		 EXP
ISO		 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]; 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]
1-aminobenzotriazole results in decreased activity of CYP2E1 protein
1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]		 CTD PMID:10828257 PMID:12704224 PMID:15618748 PMID:25243916 PMID:27421776 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] CTD PMID:24555085 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ECH1 protein] CTD PMID:32435916 NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672 		JBrowse link
G Ftcd formiminotransferase cyclodeaminase multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of FTCD protein] CTD PMID:32435916 NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172 		JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased expression of FTH1 protein] CTD PMID:32435916 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462 		JBrowse link
G Ftl1 ferritin light polypeptide 1 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of FTL1 protein] CTD PMID:32435916 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; 1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [1-aminobenzotriazole co-treated with ochratoxin A] results in increased activity of GPT protein; [Emodin co-treated with 1-aminobenzotriazole] results in increased expression of GPT protein CTD PMID:25900201 PMID:34492313 PMID:36227364 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of GSTM1 protein] CTD PMID:32435916 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein] CTD PMID:28300663 PMID:29722447 PMID:35279910 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of HAVCR1 protein CTD PMID:36227364 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [[Acetaminophen co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Butylated Hydroxyanisole co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Diclofenac co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Ticlopidine co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA] CTD PMID:18227147 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Inmt indolethylamine N-methyltransferase multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of INMT protein] CTD PMID:32435916 NCBI chr 6:55,147,612...55,151,975
Ensembl chr 6:55,147,611...55,152,028 		JBrowse link
G Krt8 keratin 8 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of KRT8 protein] CTD PMID:32435916 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of LCN2 protein CTD PMID:36227364 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Mup2 major urinary protein 2 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of MUP2 protein] CTD PMID:32435916 NCBI chr 4:60,135,913...60,139,977
Ensembl chr 4:60,135,932...60,154,289 		JBrowse link
G Rgn regucalcin multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of RGN protein] CTD PMID:32435916 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328 		JBrowse link
G Selenbp2 selenium binding protein 2 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of SELENBP2 protein] CTD PMID:32435916 NCBI chr 3:94,600,880...94,611,713
Ensembl chr 3:94,600,863...94,611,720 		JBrowse link
G Ubp1 upstream binding protein 1 multiple interactions EXP 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of UBP1 protein] CTD PMID:32435916 NCBI chr 9:113,760,002...113,807,095
Ensembl chr 9:113,760,002...113,806,270 		JBrowse link
1-phenylimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:7710944 PMID:21842885 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
3,3'-diindolylmethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
increases expression		 ISO [3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA] CTD PMID:25542144 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Actg1 actin, gamma, cytoplasmic 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of ACTG1 mRNA] CTD PMID:11179685 NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of ADGRE1 mRNA] CTD PMID:24162184 NCBI chr17:57,665,650...57,790,527
Ensembl chr17:57,665,691...57,790,527 		JBrowse link
G Ahr aryl-hydrocarbon receptor affects response to substance
affects localization
multiple interactions		 ISO
EXP		 AHR protein affects the susceptibility to 3,3'-diindolylmethane
3,3'-diindolylmethane affects the localization of AHR protein
3,3'-diindolylmethane binds to and results in decreased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]		 CTD PMID:8384853 PMID:9771935 PMID:11294972 PMID:16972788 PMID:19056653 More... NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of AIF1 protein] CTD PMID:24162184 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Ar androgen receptor decreases activity ISO 3,3'-diindolylmethane results in decreased activity of AR protein CTD PMID:30247711 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter] CTD PMID:16972788 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 3,3'-diindolylmethane results in increased expression of ATF3 CTD PMID:15670751 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of ATP5F1A mRNA] CTD PMID:11179685 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of BAD protein CTD PMID:22290291 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein increases expression ISO 3,3'-diindolylmethane results in increased expression of BAX protein CTD PMID:22290291 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bbc3 BCL2 binding component 3 multiple interactions ISO [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 CTD PMID:22290291 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression		 ISO
EXP		 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]
3,3'-diindolylmethane analog results in decreased expression of BCL2 mRNA
3,3'-diindolylmethane analog results in decreased expression of BCL2 protein; 3,3'-diindolylmethane results in decreased expression of BCL2 protein		 CTD PMID:16051428 PMID:16580691 PMID:22290291 PMID:26593444 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 increases expression ISO 3,3'-diindolylmethane results in increased expression of BCL2L1 mRNA; 3,3'-diindolylmethane results in increased expression of BCL2L1 protein CTD PMID:18025290 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l10 Bcl2-like 10 increases expression ISO 3,3'-diindolylmethane results in increased expression of BCL2L10 mRNA CTD PMID:22514694 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of BIRC5 protein CTD PMID:22290291 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA] CTD PMID:11179685 NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608 		JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CALM2 mRNA] CTD PMID:11179685 NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363 		JBrowse link
G Casp3 caspase 3 increases activity EXP 3,3'-diindolylmethane results in increased activity of CASP3 protein CTD PMID:21820497 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Ccn1 cellular communication network factor 1 affects methylation ISO 3,3'-diindolylmethane affects the methylation of CCN1 promoter CTD PMID:24466240 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CCNB1 CTD PMID:22290291 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO 3,3'-diindolylmethane analog results in decreased expression of CCND1 protein; 3,3'-diindolylmethane results in decreased expression of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]		 CTD PMID:16051428 PMID:22290291 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CCND3 protein CTD PMID:22514694 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects methylation ISO 3,3'-diindolylmethane affects the methylation of CCR4 promoter CTD PMID:24466240 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984 		JBrowse link
G Cd40lg CD40 ligand increases expression ISO 3,3'-diindolylmethane results in increased expression of CD40LG mRNA CTD PMID:22514694 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd69 CD69 antigen multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of CD69 protein] CTD PMID:24200994 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDC25C CTD PMID:22290291 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in decreased expression of CDH1 protein] CTD PMID:28844962 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh11 cadherin 11 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDH11 protein CTD PMID:18025290 NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CDH2 protein] CTD PMID:28844962 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity		 ISO 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in decreased activity of CDK2 protein		 CTD PMID:15611077 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDK4 protein CTD PMID:22514694 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdk6 cyclin dependent kinase 6 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDK6 protein CTD PMID:22290291 PMID:22514694 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in increased expression of CDKN1A mRNA; 3,3'-diindolylmethane results in increased expression of CDKN1A protein		 CTD PMID:12203118 PMID:15611077 PMID:18025290 PMID:22290291 PMID:22495798 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO 3,3'-diindolylmethane results in increased expression of CDKN1B protein CTD PMID:22290291 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D increases expression ISO 3,3'-diindolylmethane results in increased expression of CDKN2D protein CTD PMID:22290291 NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703 		JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of CHUK protein CTD PMID:22290291 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919 		JBrowse link
G Cks1b CDC28 protein kinase 1b multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CKS1B mRNA] CTD PMID:11179685 NCBI chr 3:89,322,779...89,325,598
Ensembl chr 3:89,322,779...89,325,690 		JBrowse link
G Ctsb cathepsin B multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSB protein] CTD PMID:28844962 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSD protein] CTD PMID:28844962 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects methylation
multiple interactions		 ISO 3,3'-diindolylmethane affects the methylation of CXCR4 promoter
3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CXCR4 protein]		 CTD PMID:24466240 PMID:28844962 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO 3,3'-diindolylmethane analog affects the localization of and results in increased expression of CYCS protein CTD PMID:16051428 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of CYP19A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP19A1 mRNA CTD PMID:11294972 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
decreases activity		 ISO 3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; [3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct
3,3'-diindolylmethane analog results in increased activity of CYP1A1 protein; 3,3'-diindolylmethane results in increased activity of CYP1A1 protein
3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane analog results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane results in decreased activity of CYP1A1 protein		 CTD PMID:8384853 PMID:9771935 PMID:11179685 PMID:11294972 PMID:11597580 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity
increases oxidation		 ISO [3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct; Quercetin inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]; resveratrol inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]
3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in decreased activity of CYP1A2 protein		 CTD PMID:8384853 PMID:15672752 PMID:16544949 PMID:19770484 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of CYP1B1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1B1 mRNA CTD PMID:11294972 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression ISO 3,3'-diindolylmethane results in increased expression of CYP2B2 protein CTD PMID:8384853 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 3,3'-diindolylmethane results in increased expression of DDIT3 protein CTD PMID:22290291 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3b DNA methyltransferase 3B decreases expression ISO 3,3'-diindolylmethane results in decreased expression of DNMT3B mRNA CTD PMID:24466240 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of EEF1G mRNA] CTD PMID:11179685 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of ERBB2 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of ERBB2 protein CTD PMID:16580691 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
decreases expression		 ISO 3,3'-diindolylmethane binds to and results in increased activity of ESR1 protein; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]
3,3'-diindolylmethane results in decreased expression of ESR1		 CTD PMID:16972788 PMID:19223575 PMID:23583297 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
increases expression		 ISO 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Tamoxifen inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA] CTD PMID:20160136 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of FAU mRNA] CTD PMID:11179685 NCBI chr19:6,107,977...6,109,554
Ensembl chr19:6,107,874...6,109,554 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO 3,3'-diindolylmethane results in increased expression of GDF15 mRNA CTD PMID:15670751 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Gnas GNAS complex locus multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA] CTD PMID:11179685 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
G Greb1 gene regulated by estrogen in breast cancer protein increases expression ISO 3,3'-diindolylmethane results in increased expression of GREB1 mRNA CTD PMID:23583297 NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of GSK3B protein CTD PMID:22290291 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression
multiple interactions		 ISO 3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA
[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct		 CTD PMID:19770484 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G H3f3a H3.3 histone A multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of H3-3A mRNA] CTD PMID:11179685 NCBI chr 1:180,630,125...180,641,127
Ensembl chr 1:180,628,397...180,641,508 		JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC1 mRNA] CTD PMID:24200994 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Hdac10 histone deacetylase 10 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC10 mRNA] CTD PMID:24200994 NCBI chr15:89,007,506...89,012,903
Ensembl chr15:89,007,510...89,012,903 		JBrowse link
G Hdac2 histone deacetylase 2 decreases expression
multiple interactions		 ISO
EXP		 3,3'-diindolylmethane results in decreased expression of HDAC2 protein
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC2 mRNA]		 CTD PMID:22800507 PMID:24200994 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC5 mRNA] CTD PMID:24200994 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992 		JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC8 mRNA] CTD PMID:24200994 NCBI chr  X:101,328,244...101,549,005
Ensembl chr  X:101,328,245...101,548,965 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]] CTD PMID:23583297 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) increases expression ISO 3,3'-diindolylmethane results in increased expression of HRK mRNA CTD PMID:22514694 NCBI chr 5:118,307,829...118,327,543
Ensembl chr 5:118,302,713...118,327,543 		JBrowse link
G Hspa5 heat shock protein 5 decreases expression
multiple interactions		 ISO 3,3'-diindolylmethane analog results in decreased expression of HSPA5 protein
3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]		 CTD PMID:25794856 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspb1 heat shock protein 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of HSPB1 mRNA] CTD PMID:11179685 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Ifng interferon gamma multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IFNG protein] CTD PMID:24200994 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL2 protein] CTD PMID:24200994 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO
EXP		 3,3'-diindolylmethane results in increased expression of IL6 mRNA
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL6 protein]		 CTD PMID:18025290 PMID:24200994 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Kdr kinase insert domain protein receptor decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of KDR protein CTD PMID:25794856 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Klf10 Kruppel-like transcription factor 10 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of KLF10 mRNA] CTD PMID:11179685 NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950 		JBrowse link
G Krt18 keratin 18 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA] CTD PMID:11179685 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462 		JBrowse link
G Krt19 keratin 19 multiple interactions
increases expression		 ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT19 mRNA]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA] CTD PMID:11179685 PMID:20160136 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491 		JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MAGEA9 mRNA] CTD PMID:11179685 NCBI chr  X:63,217,154...63,222,385
Ensembl chr  X:63,217,154...63,222,384 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK1 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:16580691 PMID:22290291 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO 3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK3 protein		 CTD PMID:16580691 PMID:22290291 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression EXP 3,3'-diindolylmethane analog results in decreased expression of MDM2 mRNA CTD PMID:26593444 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP2 protein] CTD PMID:28844962 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO 3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]; 3,3'-diindolylmethane analog results in decreased expression of and results in decreased activity of MMP9 protein; 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP9 protein] CTD PMID:25794856 PMID:28844962 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G mt-Co2 cytochrome c oxidase II, mitochondrial multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of COX2 mRNA] CTD PMID:11179685 NCBI chr MT:7,013...7,696
Ensembl chr MT:7,013...7,696 		JBrowse link
G Myb myeloblastosis oncogene decreases expression EXP 3,3'-diindolylmethane analog results in decreased expression of MYB mRNA CTD PMID:26593444 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883 		JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO
EXP		 3,3'-diindolylmethane results in decreased expression of MYC protein
3,3'-diindolylmethane analog results in decreased expression of MYC mRNA		 CTD PMID:22290291 PMID:26593444 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myl6 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MYL6 mRNA] CTD PMID:11179685 NCBI chr10:128,326,728...128,329,755
Ensembl chr10:128,326,729...128,330,014 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr 1:13,209,329...13,444,451
Ensembl chr 1:13,209,329...13,444,307 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression
multiple interactions		 ISO 3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA; 3,3'-diindolylmethane results in increased expression of NFE2L2 protein
sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA]; sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 protein]		 CTD PMID:23583297 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:24162184 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions
increases expression		 ISO 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]
3,3'-diindolylmethane results in increased expression of NQO1 mRNA		 CTD PMID:15672752 PMID:22495798 PMID:23583297 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO 3,3'-diindolylmethane results in increased activity of NR1I2 protein
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:25542144 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of NUMA1 protein] CTD PMID:26251508 NCBI chr 7:101,583,169...101,664,166
Ensembl chr 7:101,583,318...101,664,171 		JBrowse link
G Nup133 nucleoporin 133 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of NUP133 mRNA] CTD PMID:11179685 NCBI chr 8:124,623,862...124,676,019
Ensembl chr 8:124,623,862...124,676,004 		JBrowse link
G Papola poly (A) polymerase alpha multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of PAPOLA mRNA] CTD PMID:11179685 NCBI chr12:105,750,926...105,805,208
Ensembl chr12:105,750,953...105,805,203 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO [3,3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:16580691 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO 3,3'-diindolylmethane results in increased expression of PLAU mRNA CTD PMID:18025290 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1 CTD PMID:22290291 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in decreased expression of PTEN protein] CTD PMID:26251508 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO
EXP		 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 protein]
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of PTGS2 protein]
3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
3,3'-diindolylmethane results in decreased expression of PTGS2 mRNA; 3,3'-diindolylmethane results in decreased expression of PTGS2 protein		 CTD PMID:19056653 PMID:22290291 PMID:24162184 PMID:26251508 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases expression
multiple interactions		 ISO 3,3'-diindolylmethane results in decreased expression of RELA protein
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased phosphorylation of RELA protein]		 CTD PMID:22290291 PMID:26251508 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Ribc1 RIB43A domain with coiled-coils 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RIBC1 mRNA] CTD PMID:11179685 NCBI chr  X:150,787,576...150,799,884
Ensembl chr  X:150,787,578...150,799,291 		JBrowse link
G Rpl10 ribosomal protein L10 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]; 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL10 mRNA] CTD PMID:11179685 NCBI chr  X:73,314,463...73,316,741
Ensembl chr  X:73,314,418...73,316,741 		JBrowse link
G Rpl13a ribosomal protein L13A multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL13A mRNA] CTD PMID:11179685 NCBI chr 7:44,774,987...44,778,169
Ensembl chr 7:44,774,982...44,778,185 		JBrowse link
G Rpl31 ribosomal protein L31 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL31 mRNA] CTD PMID:11179685 NCBI chr 1:39,406,987...39,410,992
Ensembl chr 1:39,406,923...39,410,992 		JBrowse link
G Rpl41 ribosomal protein L41 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPL41 mRNA] CTD PMID:11179685 NCBI chr10:128,383,979...128,385,037
Ensembl chr10:128,383,983...128,385,174 		JBrowse link
G Rpl7 ribosomal protein L7 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL7 mRNA] CTD PMID:11179685 NCBI chr 1:16,171,519...16,174,657
Ensembl chr 1:16,171,519...16,174,886 		JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPLP0 mRNA] CTD PMID:11179685 NCBI chr 5:115,697,526...115,701,788
Ensembl chr 5:115,697,526...115,701,786 		JBrowse link
G Rps15a ribosomal protein S15A multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS15A mRNA] CTD PMID:11179685 NCBI chr 7:117,703,597...117,715,370
Ensembl chr 7:117,703,595...117,715,411 		JBrowse link
G Rps17 ribosomal protein S17 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS17 mRNA] CTD PMID:11179685 NCBI chr 7:80,992,481...80,994,982
Ensembl chr 7:80,992,480...80,995,002 		JBrowse link
G Rps3 ribosomal protein S3 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPS3 mRNA] CTD PMID:11179685 NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945 		JBrowse link
G Rps4x ribosomal protein S4, X-linked multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS4X mRNA] CTD PMID:11179685 NCBI chr  X:101,228,548...101,232,929
Ensembl chr  X:101,228,547...101,233,000 		JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS6 mRNA] CTD PMID:11179685 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649 		JBrowse link
G Snai1 snail family zinc finger 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI1 protein] CTD PMID:28844962 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Snai2 snail family zinc finger 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI2 protein] CTD PMID:28844962 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter] CTD PMID:16972788 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I affects methylation ISO 3,3'-diindolylmethane affects the methylation of TGFBR1 promoter CTD PMID:24466240 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of TIMP1 protein CTD PMID:25794856 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tmem121b transmembrane protein 121B multiple interactions
increases expression		 ISO 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr 6:120,465,900...120,470,907
Ensembl chr 6:120,465,900...120,470,768 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 ISO
EXP		 3,3'-diindolylmethane results in decreased expression of TNF mRNA
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of TNF protein]
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of TNF protein]		 CTD PMID:22514694 PMID:24200994 PMID:26251508 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression ISO 3,3'-diindolylmethane results in increased expression of TNFRSF1A mRNA CTD PMID:22514694 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf25 tumor necrosis factor receptor superfamily, member 25 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of TNFRSF25 mRNA CTD PMID:22514694 NCBI chr 4:152,199,985...152,204,568
Ensembl chr 4:152,200,391...152,204,576 		JBrowse link
G Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 increases expression ISO 3,3'-diindolylmethane results in increased expression of TNFSF8 mRNA CTD PMID:22514694 NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584 		JBrowse link
G Traf4 TNF receptor associated factor 4 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of TRAF4 mRNA CTD PMID:22514694 NCBI chr11:78,049,249...78,056,405
Ensembl chr11:78,049,325...78,056,415 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO 3,3'-diindolylmethane results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1; Wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein] CTD PMID:22290291 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tyms thymidylate synthase multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of TYMS mRNA] CTD PMID:11179685 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
G Ubb ubiquitin B multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of UBB mRNA] CTD PMID:11179685 NCBI chr11:62,442,329...62,444,037
Ensembl chr11:62,441,997...62,444,039 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO 3,3'-diindolylmethane results in decreased expression of XIAP protein CTD PMID:22290291 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of XRCC6 mRNA] CTD PMID:11179685 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 multiple interactions EXP [CYP2C37 protein results in increased metabolism of Omeprazole] which results in increased chemical synthesis of 5-hydroxymethylomeprazole CTD PMID:30503582 NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687 		JBrowse link
alpha-naphthoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 multiple interactions ISO [alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter] CTD PMID:29094188 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001 		JBrowse link
G Ahr aryl-hydrocarbon receptor affects binding
decreases activity
multiple interactions		 ISO
EXP		 [alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein; [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein; [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein; alpha-naphthoflavone binds to AHR protein
alpha-naphthoflavone results in decreased activity of AHR protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein]; AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of AHR mRNA]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Benzo(a)pyrene; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Hexachlorobenzene; [alpha-naphthoflavone results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased abundance of Reactive Oxygen Species]; alpha-naphthoflavone analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Oxygen deficiency co-treated with Tetrachlorodibenzodioxin] results in decreased stability of AHR protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]; alpha-naphthoflavone inhibits the reaction [AHR protein binds to and results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]		 CTD PMID:1329656 PMID:7669069 PMID:8390116 PMID:8738555 PMID:9006915 More... NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
increases methylation		 ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA]
alpha-naphthoflavone results in increased methylation of AKT1 promoter		 CTD PMID:29094188 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Ar androgen receptor multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of AR protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]
alpha-naphthoflavone results in increased expression of AR protein		 CTD PMID:12970580 PMID:15041469 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO
EXP		 alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]
ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]		 CTD PMID:11768231 PMID:21127131 PMID:30508555 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of BAX mRNA]
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]		 CTD PMID:20562217 PMID:29094188 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bmp15 bone morphogenetic protein 15 multiple interactions ISO [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA CTD PMID:29094188 NCBI chr  X:6,226,108...6,232,778
Ensembl chr  X:6,226,161...6,232,775 		JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]
alpha-naphthoflavone results in increased expression of BPGM mRNA		 CTD PMID:23152189 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548 		JBrowse link
G Brca1 breast cancer 1, early onset multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA] CTD PMID:16489025 PMID:18259752 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Calr calreticulin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA] CTD PMID:29094188 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Casp12 caspase 12 increases cleavage EXP alpha-naphthoflavone results in increased cleavage of CASP12 protein CTD PMID:30508555 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
decreases activity		 EXP
ISO		 alpha-naphthoflavone results in increased activity of CASP3 protein
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased cleavage of CASP3 protein]
alpha-naphthoflavone results in increased cleavage of CASP3 protein
alpha-naphthoflavone results in decreased activity of CASP3 protein		 CTD PMID:15710172 PMID:18334599 PMID:30508555 PMID:35908932 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 increases activity EXP alpha-naphthoflavone results in increased activity of CASP8 protein CTD PMID:18334599 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions		 EXP
ISO		 alpha-naphthoflavone results in increased activity of CASP9 protein
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]		 CTD PMID:18334599 PMID:29094188 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein] CTD PMID:20600218 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CCL1] CTD PMID:16679317 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
multiple interactions		 ISO alpha-naphthoflavone results in decreased expression of CCL2 mRNA
alpha-naphthoflavone results in increased expression of CCL2 mRNA
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL2 mRNA]		 CTD PMID:22262711 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA] CTD PMID:25051199 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of CCND1 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of CCND1 protein] CTD PMID:31364906 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cd9 CD9 antigen multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA] CTD PMID:29094188 NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CDC25C mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDC25C protein] CTD PMID:22266097 PMID:25051199 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in decreased expression of CDH1 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in decreased expression of CDH1 protein] CTD PMID:31364906 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh13 cadherin 13 multiple interactions ISO AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH13 mRNA] CTD PMID:12559965 NCBI chr 8:119,010,150...120,051,668
Ensembl chr 8:119,010,472...120,051,660 		JBrowse link
G Cdk1 cyclin dependent kinase 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDK1 protein] CTD PMID:22266097 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of CDK2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]		 CTD PMID:29094188 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [eupatorin-5-methyl ether results in increased expression of CDKN1A protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein] CTD PMID:21887816 PMID:22266097 PMID:23994263 PMID:24361490 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1B protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDKN1B protein] CTD PMID:15157999 PMID:22266097 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of CEBPD mRNA] CTD PMID:21652769 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]] CTD PMID:11165043 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases expression
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA]
alpha-naphthoflavone results in decreased expression of CXCL8 mRNA
alpha-naphthoflavone results in increased expression of CXCL8 mRNA		 CTD PMID:22262711 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cygb cytoglobin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] CTD PMID:25781201 NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO alpha-naphthoflavone results in decreased expression of CYP17A1 mRNA CTD PMID:24875446 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO [alpha-naphthoflavone results in decreased activity of CYP19A1 protein] which results in decreased susceptibility to o,p'-DDT; alpha-naphthoflavone binds to and results in decreased activity of CYP19A1 protein; alpha-naphthoflavone inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein]
alpha-naphthoflavone results in increased expression of CYP19A1 protein		 CTD PMID:9435150 PMID:20678559 PMID:20823264 PMID:21296134 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
affects binding
increases expression
multiple interactions
decreases activity		 ISO
EXP		 alpha-naphthoflavone results in increased activity of CYP1A1 protein
CYP1A1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A1 mRNA
alpha-naphthoflavone analog results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 protein
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [afimoxifene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Calcitriol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Resveratrol results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [STO 609 results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone results in decreased activity of CYP1A1 protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; [alpha-naphthoflavone results in decreased activity of CYP1A1 protein] inhibits the reaction [Vinyl Compounds analog results in decreased susceptibility to sodium arsenite]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [norisoboldine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone analog results in increased activity of CYP1A1 protein		 CTD PMID:1329656 PMID:6477826 PMID:7669069 PMID:8390116 PMID:8637871 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects binding
increases expression
increases metabolic processing
affects metabolic processing
decreases activity		 ISO
EXP		 [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin; alpha-naphthoflavone binds to and results in decreased activity of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A2 protein
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with alpha-naphthoflavone] results in increased expression of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein results in increased metabolism of alpha-naphthoflavone
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde
alpha-naphthoflavone results in increased expression of CYP1A2 mRNA; alpha-naphthoflavone results in increased expression of CYP1A2 protein
CYP1A2 protein affects the metabolism of alpha-naphthoflavone		 CTD PMID:2180560 PMID:9305587 PMID:15306208 PMID:15766918 PMID:15860655 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
affects binding
increases metabolic processing
increases expression
decreases expression
decreases activity		 ISO
EXP		 alpha-naphthoflavone binds to and results in decreased activity of CYP1B1 protein; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]; alpha-naphthoflavone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CYP1B1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
CYP1B1 protein results in increased metabolism of alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein]; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]
alpha-naphthoflavone results in increased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased activity of CYP1B1 protein		 CTD PMID:11577022 PMID:15075337 PMID:15280921 PMID:16120791 PMID:19182260 More... NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]] CTD PMID:19244278 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065 		JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA] CTD PMID:18467041 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085 		JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 decreases activity ISO alpha-naphthoflavone results in decreased activity of CYP2J2 protein CTD PMID:12851038 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815 		JBrowse link
G Dazl deleted in azoospermia-like multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA] CTD PMID:20562217 NCBI chr17:50,586,422...50,600,627
Ensembl chr17:50,586,423...50,600,664 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; pyrazolanthrone inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SB 203580 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein] CTD PMID:30508555 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Ddr2 discoidin domain receptor family, member 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA] CTD PMID:29094188 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331 		JBrowse link
G Ddx4 DEAD box helicase 4 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA] CTD PMID:20562217 NCBI chr13:112,734,867...112,790,342
Ensembl chr13:112,734,867...112,789,009 		JBrowse link
G Ddx5 DEAD box helicase 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA] CTD PMID:29094188 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA] CTD PMID:29094188 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of DNAJB6 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]		 CTD PMID:29094188 NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132 		JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein] CTD PMID:19578757 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EGLN1 mRNA] CTD PMID:18072750 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation EXP alpha-naphthoflavone results in increased phosphorylation of EIF2S1 protein CTD PMID:30508555 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
G Eno1 enolase 1, alpha non-neuron multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENO1 mRNA] CTD PMID:23152189 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Oxygen deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA] CTD PMID:19028555 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) affects binding
multiple interactions		 ISO [alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of ESR1 protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Estradiol binds to ESR1 protein]]
[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA]		 CTD PMID:10620335 PMID:15253042 PMID:22975028 PMID:29094188 PMID:35181438 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO [alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA CTD PMID:22975028 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Esrra estrogen related receptor, alpha affects binding ISO [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein CTD PMID:10620335 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FAS mRNA] CTD PMID:16940415 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FASL mRNA] CTD PMID:16940415 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:20876236 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Flg filaggrin multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA] CTD PMID:21835898 NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of FOS mRNA]] CTD PMID:10478842 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Foxn3 forkhead box N3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA] CTD PMID:29094188 NCBI chr12:99,156,340...99,529,926
Ensembl chr12:99,156,337...99,529,841 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of FOXO3 protein]
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA		 CTD PMID:22266097 PMID:29094188 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Foxp3 forkhead box P3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of FOXP3 mRNA] CTD PMID:26640276 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FSHR protein] CTD PMID:20823264 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Gdf9 growth differentiation factor 9 multiple interactions
increases expression		 ISO [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA
alpha-naphthoflavone results in increased expression of GDF9 mRNA		 CTD PMID:29094188 NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731 		JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GPI mRNA]
alpha-naphthoflavone results in increased expression of GPI mRNA		 CTD PMID:23152189 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Gsr glutathione reductase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSR mRNA] CTD PMID:23152189 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 decreases expression ISO alpha-naphthoflavone results in decreased expression of GSTP1 mRNA CTD PMID:18762178 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA] CTD PMID:29094188 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Hk1 hexokinase 1 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HK1 mRNA]
alpha-naphthoflavone results in increased expression of HK1 mRNA		 CTD PMID:23152189 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR protein] CTD PMID:19931295 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Hspa8 heat shock protein 8 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA] CTD PMID:29094188 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA] CTD PMID:26519956 PMID:29094188 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases acetylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased acetylation of IGF2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]		 CTD PMID:29094188 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions
increases expression		 ISO AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein] CTD PMID:23639626 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 protein]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of IL10 mRNA]		 CTD PMID:11737050 PMID:17681673 PMID:26640276 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression		 ISO
EXP		 alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B protein]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]
alpha-naphthoflavone results in increased expression of IL1B mRNA
alpha-naphthoflavone results in decreased expression of IL1B mRNA		 CTD PMID:14993811 PMID:15019843 PMID:18617548 PMID:21127131 PMID:22262711 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1RN mRNA]
alpha-naphthoflavone results in increased expression of IL1RN mRNA		 CTD PMID:22262711 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]
alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]
alpha-naphthoflavone results in increased expression of IL6 mRNA		 CTD PMID:21162728 PMID:26519956 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itgb8 integrin beta 8 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA] CTD PMID:29094188 NCBI chr12:119,121,757...119,202,891
Ensembl chr12:119,121,757...119,202,537 		JBrowse link
G Jag1 jagged 1 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of JAG1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]		 CTD PMID:29094188 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of JUN protein]
alpha-naphthoflavone results in increased expression of JUN mRNA		 CTD PMID:15019843 PMID:15897893 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Krt14 keratin 14 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of KRT14 mRNA] CTD PMID:25051199 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LDHA mRNA]
alpha-naphthoflavone results in increased expression of LDHA mRNA		 CTD PMID:23152189 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LHCGR protein] CTD PMID:20823264 NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK1 protein]
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK1 protein]		 CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK3 protein]
alpha-naphthoflavone results in increased phosphorylation of MAPK3 protein
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK3 protein]		 CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA] CTD PMID:19578757 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA]		 CTD PMID:15075337 PMID:19022365 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP2 mRNA]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP2 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP2 protein]		 CTD PMID:19022365 PMID:31364906 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP3 mRNA] CTD PMID:19022365 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP9 mRNA]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP9 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP9 protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of and results in increased activity of MMP9 protein]		 CTD PMID:19022365 PMID:23462309 PMID:31364906 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP alpha-naphthoflavone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of MTOR protein] CTD PMID:22266097 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myc myelocytomatosis oncogene multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MYC mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MYC protein]		 CTD PMID:22100782 PMID:31364906 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myog myogenin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYOG protein] CTD PMID:24431215 NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NCF1 mRNA] CTD PMID:19559082 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS1 mRNA] CTD PMID:23152189 NCBI chr 1:63,182,751...63,215,981
Ensembl chr 1:63,182,755...63,215,992 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS3 mRNA] CTD PMID:23152189 NCBI chr 2:90,724,971...90,735,065
Ensembl chr 2:90,724,978...90,735,171 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NFATC1 protein] CTD PMID:19028555 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression		 ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]
alpha-naphthoflavone results in increased expression of NOS2 protein		 CTD PMID:26086121 PMID:33722737 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Notch2 notch 2 increases methylation
multiple interactions
decreases acetylation		 ISO alpha-naphthoflavone results in increased methylation of NOTCH2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]
alpha-naphthoflavone results in decreased acetylation of NOTCH2 promoter		 CTD PMID:29094188 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases activity
increases expression		 ISO alpha-naphthoflavone results in increased activity of NQO1 protein
alpha-naphthoflavone results in increased expression of NQO1 mRNA		 CTD PMID:16906435 PMID:17069994 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO alpha-naphthoflavone results in increased activity of NR1I3 protein CTD PMID:27732639 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 affects binding ISO [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein CTD PMID:10620335 NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage EXP alpha-naphthoflavone results in increased cleavage of PARP1 protein CTD PMID:30508555 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PFKM mRNA]
alpha-naphthoflavone results in increased expression of PFKM mRNA		 CTD PMID:23152189 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGK1 mRNA]
alpha-naphthoflavone results in increased expression of PGK1 mRNA		 CTD PMID:23152189 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305 		JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression
multiple interactions		 ISO alpha-naphthoflavone results in increased expression of PGM1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNA]		 CTD PMID:23152189 NCBI chr 4:99,786,648...99,844,491
Ensembl chr 4:99,786,611...99,844,491 		JBrowse link
G Pgr progesterone receptor increases expression ISO alpha-naphthoflavone results in increased expression of PGR protein CTD PMID:22266097 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pkm pyruvate kinase, muscle multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of PPARA protein] CTD PMID:21849270 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA] CTD PMID:20562217 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of PRKCB protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of PRKCB protein] CTD PMID:16797713 PMID:17222441 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Prl prolactin multiple interactions ISO alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of PRL mRNA] CTD PMID:22975028 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
increases expression		 ISO
EXP		 alpha-naphthoflavone results in decreased expression of PTGS2 mRNA
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone results in increased expression of PTGS2 mRNA		 CTD PMID:21162728 PMID:21652769 PMID:22262711 PMID:26358519 PMID:27393915 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein] CTD PMID:16359657 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RACK1 protein] CTD PMID:16797713 PMID:17222441 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] CTD PMID:15157999 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
decreases expression		 ISO
EXP		 alpha-naphthoflavone inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]
alpha-naphthoflavone results in decreased expression of RELA protein		 CTD PMID:24431215 PMID:33722737 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Saa1 serum amyloid A 1 multiple interactions ISO alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA] CTD PMID:21127131 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404 		JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 multiple interactions
decreases expression
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]]
alpha-naphthoflavone results in decreased expression of SERPINB2 mRNA
alpha-naphthoflavone results in increased expression of SERPINB2 mRNA		 CTD PMID:15075337 PMID:22262711 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA]
alpha-naphthoflavone results in increased expression of SLC2A1 mRNA		 CTD PMID:23152189 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 protein] CTD PMID:26519956 NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] CTD PMID:27519288 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of SP1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of SP1 mRNA] CTD PMID:29094188 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839 		JBrowse link
G Src Rous sarcoma oncogene multiple interactions
increases phosphorylation		 EXP SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]
alpha-naphthoflavone results in increased phosphorylation of SRC protein		 CTD PMID:30508555 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein] CTD PMID:21205633 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Synb syncytin b multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA] CTD PMID:24361490 NCBI chr14:69,527,827...69,549,857
Ensembl chr14:69,526,793...69,531,748 		JBrowse link
G Tcf7 transcription factor 7, T cell specific increases expression ISO alpha-naphthoflavone results in increased expression of TCF7 mRNA CTD PMID:18762178 NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of TGFB1 mRNA]
alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of TGFB1 mRNA]		 CTD PMID:22975028 PMID:27519288 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase decreases expression
multiple interactions		 ISO alpha-naphthoflavone results in decreased expression of TIPARP mRNA
alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of TIPARP mRNA]		 CTD PMID:18762178 PMID:21652769 NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of TNF mRNA]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]		 CTD PMID:17934341 PMID:20801209 PMID:23099484 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1A protein] CTD PMID:34200499 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b multiple interactions ISO alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1B protein] CTD PMID:34200499 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]] CTD PMID:26221077 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression
multiple interactions		 ISO alpha-naphthoflavone results in increased expression of TPI1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TPI1 mRNA]		 CTD PMID:23152189 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression		 ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]
alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]
alpha-naphthoflavone results in increased expression of TP53 protein
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of TRP53 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene affects the localization of TRP53 protein]		 CTD PMID:9006915 PMID:15459018 PMID:29274324 PMID:32553695 PMID:35908932 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]] CTD PMID:19244278 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO
EXP		 alpha-naphthoflavone affects the reaction [Hexachlorobenzene results in increased expression of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA protein]; alpha-naphthoflavone promotes the reaction [Chlorpyrifos results in increased expression of VEGFA protein]
alpha-naphthoflavone inhibits the reaction [norisoboldine results in decreased expression of VEGFA mRNA]
alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]]		 CTD PMID:19182260 PMID:26221077 PMID:26358519 PMID:32526215 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vim vimentin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of VIM mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of VIM protein] CTD PMID:31364906 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Wapl WAPL cohesin release factor multiple interactions ISO alpha-naphthoflavone promotes the reaction [3-methylcholanthrylene results in increased expression of WAPL mRNA] CTD PMID:15797623 NCBI chr14:34,394,086...34,469,940
Ensembl chr14:34,395,885...34,469,940 		JBrowse link
amentoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein] CTD PMID:34599948 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:28185818 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein] CTD PMID:28185818 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO
EXP		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]		 CTD PMID:28185818 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form] CTD PMID:28185818 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 mRNA]; amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]] CTD PMID:34599948 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:28185818 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO amentoflavone results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Dct dopachrome tautomerase decreases expression ISO amentoflavone analog results in decreased expression of DCT mRNA; amentoflavone analog results in decreased expression of DCT protein CTD PMID:17473463 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] CTD PMID:28185818 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein] CTD PMID:28185818 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein] CTD PMID:28185818 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein] CTD PMID:28185818 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression
multiple interactions		 ISO
EXP		 amentoflavone results in decreased expression of NOS2 protein
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]		 CTD PMID:12144868 PMID:28185818 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]] CTD PMID:34599948 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptgds prostaglandin D2 synthase (brain) affects binding ISO amentoflavone binds to PTGDS protein CTD PMID:26456343 NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO amentoflavone results in decreased expression of PTGS2 mRNA; amentoflavone results in decreased expression of PTGS2 protein
[amentoflavone results in decreased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone		 CTD PMID:12144868 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO amentoflavone results in decreased expression of SREBF1 mRNA CTD PMID:34599948 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:28185818 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Tyr tyrosinase decreases activity ISO amentoflavone analog results in decreased activity of TYR protein CTD PMID:17473463 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases activity ISO amentoflavone results in decreased activity of UGT1A1 protein CTD PMID:29470958 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 decreases activity ISO amentoflavone results in decreased activity of UGT1A10 protein CTD PMID:29470958 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO amentoflavone results in decreased activity of UGT1A3 protein CTD PMID:29470958 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 decreases activity ISO amentoflavone results in decreased activity of UGT1A4 protein CTD PMID:29470958 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B decreases activity
multiple interactions		 ISO amentoflavone results in decreased activity of UGT1A6 protein
amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol]		 CTD PMID:29470958 PMID:32421801 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases activity ISO amentoflavone results in decreased activity of UGT1A9 protein CTD PMID:29470958 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO amentoflavone results in decreased activity of UGT2B17 protein CTD PMID:29470958 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
aminoglutethimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp1 acid phosphatase 1, soluble decreases expression ISO Aminoglutethimide results in decreased expression of ACP1 protein CTD PMID:26102013 NCBI chr12:30,943,325...30,961,616
Ensembl chr12:30,943,325...30,961,588 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B decreases expression ISO Aminoglutethimide results in decreased expression of ANP32B protein CTD PMID:26102013 NCBI chr 4:46,450,926...46,472,657
Ensembl chr 4:46,450,902...46,472,657 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO Aminoglutethimide results in decreased expression of BASP1 protein CTD PMID:26102013 NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850 		JBrowse link
G Bcap31 B cell receptor associated protein 31 decreases expression ISO Aminoglutethimide results in decreased expression of BCAP31 protein CTD PMID:26102013 NCBI chr  X:72,729,784...72,761,464
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO Aminoglutethimide results in increased expression of CCT4 protein CTD PMID:26102013 NCBI chr11:22,940,593...22,953,336
Ensembl chr11:22,940,519...22,953,780 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A decreases expression ISO Aminoglutethimide results in decreased expression of CCT6A protein CTD PMID:26102013 NCBI chr 5:129,864,420...129,875,284
Ensembl chr 5:129,864,062...129,875,212 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Aminoglutethimide results in decreased expression of CCT7 protein CTD PMID:26102013 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457 		JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO Aminoglutethimide results in increased expression of COMT protein CTD PMID:26102013 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression ISO Aminoglutethimide results in decreased expression of CUTA protein CTD PMID:26102013 NCBI chr17:27,156,946...27,158,847
Ensembl chr17:27,152,793...27,158,543 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA] CTD PMID:16935330 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Aminoglutethimide results in decreased expression of CYP17A1 mRNA CTD PMID:16935330 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases activity
decreases activity		 ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]
Aminoglutethimide results in increased activity of CYP19A1 protein
Aminoglutethimide results in decreased activity of CYP19A1 protein		 CTD PMID:15242824 PMID:15968818 PMID:16935330 PMID:17910019 PMID:20087668 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Fshb follicle stimulating hormone beta decreases expression
multiple interactions		 ISO
EXP		 Aminoglutethimide results in decreased expression of FSHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]		 CTD PMID:9208491 PMID:22285649 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001 		JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A increases expression ISO Aminoglutethimide results in increased expression of GATD3 protein CTD PMID:26102013 NCBI chr10:77,997,900...78,005,589
Ensembl chr10:77,997,900...78,005,616 		JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase decreases expression ISO Aminoglutethimide results in decreased expression of GNS protein CTD PMID:26102013 NCBI chr10:121,200,995...121,233,159
Ensembl chr10:121,200,995...121,233,154 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Aminoglutethimide results in increased expression of GPX1 protein CTD PMID:26102013 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gsn gelsolin decreases expression ISO Aminoglutethimide results in decreased expression of GSN protein CTD PMID:26102013 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Aminoglutethimide results in increased expression of H1-2 protein CTD PMID:26102013 NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350 		JBrowse link
G H2ac12 H2A clustered histone 12 increases expression ISO Aminoglutethimide results in increased expression of H2AC12 protein CTD PMID:26102013 NCBI chr13:22,219,292...22,219,813
Ensembl chr13:22,219,334...22,219,738 		JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression ISO Aminoglutethimide results in increased expression of H2AZ1 protein CTD PMID:26102013 NCBI chr 3:137,570,248...137,572,683
Ensembl chr 3:137,570,248...137,572,683 		JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO Aminoglutethimide results in increased expression of H2BC12 protein CTD PMID:26102013 NCBI chr13:22,219,991...22,220,490
Ensembl chr13:22,220,040...22,220,515 		JBrowse link
G H3c11 H3 clustered histone 11 increases expression ISO Aminoglutethimide results in increased expression of H3C7 protein CTD PMID:26102013 NCBI chr13:21,967,085...21,967,567
Ensembl chr13:21,967,130...21,967,540 		JBrowse link
G H3c3 H3 clustered histone 3 increases expression ISO Aminoglutethimide results in increased expression of H3C13 protein CTD PMID:26102013 NCBI chr13:23,929,025...23,929,504
Ensembl chr13:23,928,956...23,929,585 		JBrowse link
G H4c12 H4 clustered histone 12 increases expression ISO Aminoglutethimide results in increased expression of H4C8 protein CTD PMID:26102013 NCBI chr13:21,934,315...21,934,723
Ensembl chr13:21,934,364...21,934,675 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Aminoglutethimide results in decreased expression of HMGB2 protein CTD PMID:26102013 NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Aminoglutethimide results in decreased expression of HNRNPH1 protein CTD PMID:26102013 NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 multiple interactions ISO [Colforsin co-treated with Aminoglutethimide] results in decreased expression of HSD17B1 mRNA CTD PMID:16935330 NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Aminoglutethimide results in decreased expression of HSD17B10 protein CTD PMID:26102013 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions
decreases expression		 ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of HSD17B4 mRNA]
Aminoglutethimide results in decreased expression of HSD17B4 mRNA		 CTD PMID:16935330 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Aminoglutethimide results in decreased expression of HSD17B7 mRNA CTD PMID:9231770 NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810 		JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO Aminoglutethimide results in increased expression of HSPA1A protein CTD PMID:26102013 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO Aminoglutethimide results in increased expression of HYOU1 protein CTD PMID:26102013 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 decreases expression ISO Aminoglutethimide results in decreased expression of IMPDH2 protein CTD PMID:26102013 NCBI chr 9:108,437,635...108,442,776
Ensembl chr 9:108,437,485...108,442,783 		JBrowse link
G Lhb luteinizing hormone beta decreases expression
multiple interactions		 ISO
EXP		 Aminoglutethimide results in decreased expression of LHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]		 CTD PMID:9208491 PMID:22285649 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321 		JBrowse link
G Lmna lamin A decreases expression ISO Aminoglutethimide results in decreased expression of LMNA protein CTD PMID:26102013 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263 		JBrowse link
G Lmnb2 lamin B2 decreases expression ISO Aminoglutethimide results in decreased expression of LMNB2 protein CTD PMID:26102013 NCBI chr10:80,737,197...80,754,079
Ensembl chr10:80,737,037...80,754,079 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Aminoglutethimide results in decreased expression of MCM3 protein CTD PMID:26102013 NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide] which results in increased expression of MPO protein modified form; [Aminoglutethimide co-treated with Hydrogen Peroxide] results in increased oxidation of MPO protein; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide CTD PMID:20199096 PMID:26102013 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Myo18a myosin XVIIIA decreases expression ISO Aminoglutethimide results in decreased expression of MYO18A protein CTD PMID:26102013 NCBI chr11:77,654,066...77,756,806
Ensembl chr11:77,654,072...77,756,806 		JBrowse link
G Npm3 nucleoplasmin 3 decreases expression ISO Aminoglutethimide results in decreased expression of NPM3 protein CTD PMID:26102013 NCBI chr19:45,736,173...45,738,004
Ensembl chr19:45,736,173...45,738,030 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Aminoglutethimide results in increased activity of NR1I2 protein CTD PMID:21068194 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nup210 nucleoporin 210 decreases expression ISO Aminoglutethimide results in decreased expression of NUP210 protein CTD PMID:26102013 NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811 		JBrowse link
G Pgr progesterone receptor multiple interactions
decreases expression		 ISO [Aminoglutethimide co-treated with 17 alpha-Hydroxyprogesterone Caproate] results in decreased expression of PGR protein
Aminoglutethimide results in decreased expression of PGR protein		 CTD PMID:8565696 PMID:9208491 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Aminoglutethimide results in increased expression of PITPNB protein CTD PMID:26102013 NCBI chr 5:111,478,563...111,536,225
Ensembl chr 5:111,478,629...111,536,225 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO Aminoglutethimide results in decreased expression of PPP1CA protein CTD PMID:26102013 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Aminoglutethimide results in increased expression of PRDX3 protein CTD PMID:26102013 NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994 		JBrowse link
G Psmb4 proteasome (prosome, macropain) subunit, beta type 4 decreases expression ISO Aminoglutethimide results in decreased expression of PSMB4 protein CTD PMID:26102013 NCBI chr 3:94,791,635...94,794,269
Ensembl chr 3:94,791,404...94,794,272 		JBrowse link
G Rtraf RNA transcription, translation and transport factor decreases expression ISO Aminoglutethimide results in decreased expression of RTRAF protein CTD PMID:26102013 NCBI chr14:19,861,470...19,873,891
Ensembl chr14:19,861,419...19,873,892 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO Aminoglutethimide results in decreased expression of SPP1 mRNA CTD PMID:23558518 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Ssb small RNA binding exonuclease protection factor La decreases expression ISO Aminoglutethimide results in decreased expression of SSB protein CTD PMID:26102013 NCBI chr 2:69,691,963...69,702,185
Ensembl chr 2:69,691,906...69,702,190 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
increases expression		 ISO
EXP		 Aminoglutethimide results in decreased expression of STAR mRNA
Aminoglutethimide results in increased expression of STAR mRNA		 CTD PMID:10960482 PMID:16935330 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO Aminoglutethimide results in decreased expression of TPT1 protein CTD PMID:26102013 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965 		JBrowse link
G Ubc ubiquitin C increases expression ISO Aminoglutethimide results in increased expression of UBC protein CTD PMID:26102013 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K decreases expression ISO Aminoglutethimide results in decreased expression of UBE2K protein CTD PMID:26102013 NCBI chr 5:65,694,588...65,756,332
Ensembl chr 5:65,694,576...65,756,331 		JBrowse link
G Wdr1 WD repeat domain 1 increases expression ISO Aminoglutethimide results in increased expression of WDR1 protein CTD PMID:26102013 NCBI chr 5:38,684,149...38,720,265
Ensembl chr 5:38,684,156...38,720,564 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta increases expression ISO Aminoglutethimide results in increased expression of YWHAQ protein CTD PMID:26102013 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638 		JBrowse link
anastrozole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cycs cytochrome c, somatic multiple interactions ISO [Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Olive Oil co-treated with anastrozole] affects the localization of CYCS protein CTD PMID:24161488 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Anastrozole results in decreased activity of CYP19A1 protein CTD PMID:15837728 PMID:16001952 PMID:16023338 PMID:16023854 PMID:16034487 More... NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Fshb follicle stimulating hormone beta increases expression ISO anastrozole results in increased expression of FSHB protein CTD PMID:10657858 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO anastrozole results in decreased expression of GJA1 protein CTD PMID:29180066 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Lhb luteinizing hormone beta increases expression ISO anastrozole results in increased expression of LHB protein CTD PMID:10657858 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions
decreases expression		 ISO [Tamoxifen co-treated with anastrozole] results in decreased expression of MKI67 protein
anastrozole results in decreased expression of MKI67 protein		 CTD PMID:15767642 PMID:16002280 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Pgr progesterone receptor decreases expression ISO anastrozole results in decreased expression of PGR protein CTD PMID:16002280 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Por cytochrome p450 oxidoreductase decreases activity ISO Anastrozole results in decreased activity of POR protein CTD PMID:35206146 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO anastrozole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor decreases expression ISO beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr11:84,313,682...84,404,433
Ensembl chr11:84,313,681...84,404,348 		JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634 		JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression ISO beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531 		JBrowse link
G Actb actin, beta decreases expression ISO beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509 		JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 decreases expression ISO beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192 		JBrowse link
G Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr13:25,091,562...25,121,740
Ensembl chr13:25,091,562...25,121,644
Ensembl chr13:25,091,562...25,121,644 		JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 9:102,503,495...102,511,443
Ensembl chr 9:102,503,495...102,511,624 		JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr 8:123,301,376...123,303,646
Ensembl chr 8:123,301,374...123,303,648 		JBrowse link
G Ar androgen receptor multiple interactions ISO beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450 		JBrowse link
G Arpp21 cyclic AMP-regulated phosphoprotein, 21 increases expression ISO beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 9:111,894,159...112,065,356
Ensembl chr 9:111,894,159...112,065,006 		JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000 		JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 3:105,850,014...105,866,579
Ensembl chr 3:105,850,014...105,867,415 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513 		JBrowse link
G Bax BCL2-associated X protein decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of BAX mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA		 CTD PMID:29203277 PMID:32956828 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
multiple interactions		 ISO beauvericin results in increased expression of BCL2 mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA		 CTD PMID:29203277 PMID:32956828 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187 		JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 4:108,671,489...108,691,445
Ensembl chr 4:108,671,492...108,690,811 		JBrowse link
G C1qtnf3 C1q and tumor necrosis factor related protein 3 decreases expression ISO beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr15:10,952,418...10,980,248
Ensembl chr15:10,952,418...10,980,236 		JBrowse link
G C1qtnf6 C1q and tumor necrosis factor related protein 6 increases expression ISO beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr15:78,407,546...78,416,370
Ensembl chr15:78,407,546...78,415,616 		JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 4:94,388,318...94,445,033
Ensembl chr 4:94,388,318...94,445,033 		JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO beauvericin results in increased activity of CASP3 protein
[zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA		 CTD PMID:25178661 PMID:32956828 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 increases activity ISO beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 increases expression ISO beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases expression ISO beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccar2 cell cycle activator and apoptosis regulator 2 decreases expression ISO beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr14:70,375,617...70,391,272
Ensembl chr14:70,375,613...70,391,260 		JBrowse link
G Ccdc124 coiled-coil domain containing 124 decreases expression ISO beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr 8:71,320,870...71,326,134
Ensembl chr 8:71,320,871...71,326,579 		JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 4:45,890,303...45,950,774
Ensembl chr 4:45,890,303...45,950,774 		JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr19:10,918,845...10,926,630
Ensembl chr19:10,918,845...10,926,630 		JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950 		JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373 		JBrowse link
G Cd81 CD81 antigen multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Cdk2ap2 cyclin dependent kinase 2 associated protein 2 decreases expression ISO beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr19:4,146,204...4,149,019
Ensembl chr19:4,147,182...4,149,019 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression ISO beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr 5:129,910,002...129,916,311
Ensembl chr 5:129,909,997...129,916,311 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr 8:95,546,446...95,565,454
Ensembl chr 8:95,546,432...95,564,986 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555 		JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr 8:127,149,267...127,152,174
Ensembl chr 8:127,149,254...127,152,172 		JBrowse link
G Coro1c coronin, actin binding protein 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr 5:113,980,500...114,046,767
Ensembl chr 5:113,980,497...114,046,819 		JBrowse link
G Cotl1 coactosin like F-actin binding protein 1 decreases expression ISO beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr 8:120,535,953...120,567,318
Ensembl chr 8:120,535,961...120,567,283 		JBrowse link
G Cplane2 ciliogenesis and planar polarity effector 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 4:140,941,249...140,947,425
Ensembl chr 4:140,941,267...140,954,067 		JBrowse link
G Cpne1 copine I decreases expression ISO beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr 2:155,913,765...155,953,847
Ensembl chr 2:155,913,762...155,953,885 		JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr17:78,507,602...78,684,021
Ensembl chr17:78,507,677...78,684,021 		JBrowse link
G Csdc2 cold shock domain containing C2, RNA binding multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr15:81,820,960...81,835,142
Ensembl chr15:81,820,960...81,835,142 		JBrowse link
G Csk c-src tyrosine kinase decreases expression ISO beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914 		JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CXCL8 protein CTD PMID:32407736 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr17:32,671,670...32,712,294
Ensembl chr17:32,671,697...32,712,294 		JBrowse link
G Dcxr dicarbonyl L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr11:120,615,372...120,618,110
Ensembl chr11:120,616,225...120,618,107 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Ddx47 DEAD box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 6:134,988,575...135,000,739
Ensembl chr 6:134,988,575...135,000,739 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr12:72,697,127...72,711,678
Ensembl chr12:72,697,127...72,711,683 		JBrowse link
G Edem1 ER degradation enhancer, mannosidase alpha-like 1 increases expression ISO beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046 		JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 6:38,511,796...38,516,384
Ensembl chr 6:38,510,437...38,516,384 		JBrowse link
G Gaa glucosidase, alpha, acid multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr11:119,158,789...119,176,284
Ensembl chr11:119,158,713...119,176,280 		JBrowse link
G Gna14 guanine nucleotide binding protein, alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr19:16,413,031...16,590,706
Ensembl chr19:16,413,126...16,588,184 		JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462 		JBrowse link
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726 		JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 2:38,906,167...38,955,568
Ensembl chr 2:38,906,167...38,955,553 		JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863 		JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr14:122,148,846...122,153,300
Ensembl chr14:122,148,665...122,153,193 		JBrowse link
G H2bc21 H2B clustered histone 21 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 3:96,128,435...96,131,057
Ensembl chr 3:96,128,435...96,131,054 		JBrowse link
G Hexb hexosaminidase B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796 		JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr17:33,865,207...33,904,432
Ensembl chr17:33,865,207...33,905,834 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr 1:178,148,673...178,170,063
Ensembl chr 1:178,148,673...178,165,362 		JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Immt inner membrane protein, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 6:71,806,200...71,852,250
Ensembl chr 6:71,808,315...71,854,372 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660 		JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 9:58,103,580...58,113,563
Ensembl chr 9:58,103,580...58,111,602 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Klf12 Kruppel-like transcription factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr14:100,103,617...100,719,681
Ensembl chr14:100,108,068...100,522,115 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr11:97,050,536...97,078,718
Ensembl chr11:97,050,540...97,078,707 		JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr11:100,136,917...100,139,728
Ensembl chr11:100,136,917...100,139,728 		JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr11:99,236,391...99,241,944
Ensembl chr11:99,236,391...99,241,930 		JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333 		JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr15:101,792,786...101,801,355
Ensembl chr15:101,792,786...101,801,355 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331 		JBrowse link
G Lat linker for activation of T cells decreases expression ISO beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation ISO beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation ISO beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Matn4 matrilin 4 decreases expression ISO beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr 2:164,231,313...164,247,080
Ensembl chr 2:164,231,313...164,247,080 		JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945 		JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr12:81,620,331...81,641,782
Ensembl chr12:81,620,331...81,641,782 		JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA		 CTD PMID:29203277 PMID:31100301 NCBI chr11:120,375,463...120,379,580
Ensembl chr11:120,375,439...120,379,891 		JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 decreases expression ISO beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr 9:20,907,040...20,920,135
Ensembl chr 9:20,914,034...20,920,135 		JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607 		JBrowse link
G mt-Atp8 ATP synthase 8, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,766...7,969
Ensembl chr MT:7,766...7,969 		JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of COX1 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872 		JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of COX3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390 		JBrowse link
G mt-Cytb cytochrome b, mitochondrial decreases expression ISO beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288 		JBrowse link
G mt-Nd2 NADH dehydrogenase 2, mitochondrial decreases expression
increases expression
multiple interactions		 ISO beauvericin results in decreased expression of ND2 mRNA
beauvericin results in increased expression of ND2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:3,914...4,951
Ensembl chr MT:3,914...4,951 		JBrowse link
G mt-Nd3 NADH dehydrogenase 3, mitochondrial decreases expression
increases expression
multiple interactions		 ISO beauvericin results in decreased expression of ND3 mRNA
beauvericin results in increased expression of ND3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,459...9,806
Ensembl chr MT:9,459...9,806 		JBrowse link
G mt-Nd4 NADH dehydrogenase 4, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,167...11,544
Ensembl chr MT:10,167...11,544 		JBrowse link
G mt-Nd4l NADH dehydrogenase 4L, mitochondrial decreases expression
multiple interactions
increases expression		 ISO beauvericin results in decreased expression of ND4L mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4L mRNA
beauvericin results in increased expression of ND4L mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,877...10,173
Ensembl chr MT:9,877...10,173 		JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial decreases expression
increases expression
multiple interactions		 ISO beauvericin results in decreased expression of ND5 mRNA
beauvericin results in increased expression of ND5 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND5 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565 		JBrowse link
G mt-Nd6 NADH dehydrogenase 6, mitochondrial decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of ND6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND6 mRNA		 CTD PMID:34015425 NCBI chr MT:13,552...14,070
Ensembl chr MT:13,552...14,070 		JBrowse link
G mt-Rnr2 16S rRNA, mitochondrial increases expression
multiple interactions		 ISO beauvericin results in increased expression of RNR2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of RNR2 mRNA; [beauvericin co-treated with enniatins] affects the expression of RNR2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of RNR2 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:1,094...2,675
Ensembl chr MT:1,094...2,675 		JBrowse link
G Mtrf1l mitochondrial translational release factor 1-like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr10:5,760,151...5,775,015
Ensembl chr10:5,761,887...5,773,910 		JBrowse link
G Myo18a myosin XVIIIA increases expression ISO beauvericin results in increased expression of MYO18A mRNA CTD PMID:29203277 NCBI chr11:77,654,066...77,756,806
Ensembl chr11:77,654,072...77,756,806 		JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:64,632,726...64,649,586
Ensembl chr18:64,632,718...64,649,723 		JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2 (mitochondrial)(putative) multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 7:96,600,698...96,725,606
Ensembl chr 7:96,600,712...96,713,965 		JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr11:70,982,023...71,035,780
Ensembl chr11:70,983,062...71,035,530 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 increases expression ISO beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) increases expression ISO beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr 5:140,307,375...140,323,892
Ensembl chr 5:140,307,411...140,323,892 		JBrowse link
G Oga O-GlcNAcase increases expression ISO beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) increases expression ISO beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:100,683,617...100,727,957
Ensembl chr  X:100,683,666...100,727,957 		JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions
increases expression		 ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of OSGIN1 mRNA
beauvericin results in increased expression of OSGIN1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995 		JBrowse link
G Ostc oligosaccharyltransferase complex subunit (non-catalytic) multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 3:130,489,566...130,503,093
Ensembl chr 3:130,489,561...130,503,093 		JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr15:84,208,388...84,227,179
Ensembl chr15:84,208,227...84,227,179 		JBrowse link
G Pawr PRKC, apoptosis, WT1, regulator decreases expression ISO beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101 		JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr19:47,079,183...47,119,585
Ensembl chr19:47,079,207...47,120,304 		JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr17:15,739,472...15,747,560
Ensembl chr17:15,739,470...15,747,563 		JBrowse link
G Pdcd2l programmed cell death 2-like increases expression ISO beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr 7:33,883,922...33,896,154
Ensembl chr 7:33,883,924...33,896,086 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291 		JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr 7:35,341,410...35,346,907
Ensembl chr 7:35,341,407...35,346,946 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 9:113,480,812...113,537,457
Ensembl chr 9:113,480,812...113,537,327 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 decreases expression ISO beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pfn1 profilin 1 decreases expression
multiple interactions		 ISO beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein		 CTD PMID:29203277 PMID:32407736 NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305 		JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306 		JBrowse link
G Phka2 phosphorylase kinase alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:159,284,900...159,384,772
Ensembl chr  X:159,285,162...159,381,874 		JBrowse link
G Pidd1 p53 induced death domain protein 1 decreases expression ISO beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938 		JBrowse link
G Plk1 polo like kinase 1 decreases expression ISO beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096 		JBrowse link
G Pls3 plastin 3 (T-isoform) multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:74,829,259...74,918,788
Ensembl chr  X:74,829,260...74,918,788 		JBrowse link
G Potefam1 POTE ankyrin domain family member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of POTEJ protein CTD PMID:32407736 NCBI chr 2:110,880,755...111,059,948
Ensembl chr 2:110,880,755...111,059,948 		JBrowse link
G Ppa1 pyrophosphatase (inorganic) 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr10:61,484,400...61,509,944
Ensembl chr10:61,484,331...61,509,947 		JBrowse link
G Ppan peter pan homolog decreases expression ISO beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr 9:20,799,471...20,803,475
Ensembl chr 9:20,799,471...20,803,474 		JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B decreases expression ISO beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr19:6,952,416...6,954,692
Ensembl chr19:6,952,336...6,954,692 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 4:122,729,879...122,752,968
Ensembl chr 4:122,730,035...122,752,968 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754 		JBrowse link
G Psma5 proteasome subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 3:108,164,242...108,187,268
Ensembl chr 3:108,164,242...108,187,290 		JBrowse link
G Psme4 proteasome (prosome, macropain) activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr11:30,721,753...30,831,150
Ensembl chr11:30,721,726...30,830,361 		JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr10:127,894,851...127,913,123
Ensembl chr10:127,894,823...127,913,141 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 (class I) multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 6:85,311,944...85,351,663
Ensembl chr 6:85,311,944...85,351,616 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr17:53,786,262...53,814,706
Ensembl chr17:53,786,262...53,814,708 		JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr11:120,612,294...120,614,795
Ensembl chr11:120,612,296...120,614,795 		JBrowse link
G Rap1a RAS-related protein 1a multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 3:105,634,576...105,708,740
Ensembl chr 3:105,634,583...105,708,652 		JBrowse link
G Relt RELT tumor necrosis factor receptor decreases expression ISO beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr 7:100,495,054...100,512,690
Ensembl chr 7:100,495,054...100,512,653 		JBrowse link
G Rp2 retinitis pigmentosa 2 homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:20,230,778...20,271,873
Ensembl chr  X:20,230,720...20,271,892 		JBrowse link
G Rpl37a ribosomal protein L37a multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 1:72,750,426...72,752,972
Ensembl chr 1:72,750,449...72,752,972 		JBrowse link
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr 5:108,048,388...108,056,871
Ensembl chr 5:108,048,368...108,056,871 		JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr15:76,788,271...76,790,518
Ensembl chr15:76,788,278...76,790,514 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:159,865,521...160,041,214
Ensembl chr  X:159,865,521...160,041,209 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 7:120,408,853...120,431,122
Ensembl chr 7:120,411,588...120,430,416 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 6:113,705,013...113,717,642
Ensembl chr 6:113,705,023...113,717,704 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr12:112,611,262...112,615,586
Ensembl chr12:112,611,113...112,615,583 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 7:18,883,370...18,886,659
Ensembl chr 7:18,883,647...18,887,467 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr10:75,353,852...75,371,300
Ensembl chr10:75,353,385...75,373,215 		JBrowse link
G Src Rous sarcoma oncogene decreases activity ISO beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Srm spermidine synthase decreases expression ISO beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450 		JBrowse link
G Srsf7 serine and arginine-rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr17:80,507,509...80,514,734
Ensembl chr17:80,507,509...80,514,736 		JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions
decreases expression		 ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of SRXN1 mRNA
beauvericin results in decreased expression of SRXN1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296 		JBrowse link
G Ssbp1 single-stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 6:40,448,302...40,458,757
Ensembl chr 6:40,448,286...40,461,634 		JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 9:90,084,100...90,152,861
Ensembl chr 9:90,084,080...90,152,857 		JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr11:3,867,077...3,882,078
Ensembl chr11:3,867,192...3,882,159 		JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 2:104,497,587...104,542,525
Ensembl chr 2:104,487,633...104,542,514 		JBrowse link
G Tcp11l2 t-complex 11 (mouse) like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr10:84,412,811...84,450,219
Ensembl chr10:84,412,490...84,450,223 		JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 9:26,910,950...26,918,632
Ensembl chr 9:26,911,006...26,918,632 		JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr12:71,169,946...71,183,476
Ensembl chr12:71,169,947...71,183,458 		JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918 		JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr10:84,938,491...84,953,611
Ensembl chr10:84,938,491...84,956,482 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 decreases expression ISO beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr15:79,555,069...79,557,063
Ensembl chr15:79,555,062...79,557,601 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 5:24,043,942...24,049,143
Ensembl chr 5:24,043,942...24,049,159 		JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754 		JBrowse link
G Tubb4a tubulin, beta 4A class IVA multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr17:57,387,061...57,394,600
Ensembl chr17:57,387,066...57,394,782 		JBrowse link
G Tubb4b tubulin, beta 4B class IVB multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 2:25,112,170...25,114,714
Ensembl chr 2:25,112,172...25,114,714 		JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198 		JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
decreases expression		 ISO beauvericin results in increased expression of TXNIP mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of TXNIP mRNA
beauvericin results in decreased expression of TXNIP mRNA		 CTD PMID:29203277 PMID:34015425 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions
decreases expression		 ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA
beauvericin results in decreased expression of UCP2 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639 		JBrowse link
G Ybx1 Y box protein 1 decreases expression ISO beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 4:119,134,524...119,153,462
Ensembl chr 4:119,135,178...119,151,801 		JBrowse link
G Ybx3 Y box protein 3 decreases expression ISO beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr 6:131,341,821...131,365,413
Ensembl chr 6:131,341,818...131,365,439 		JBrowse link
G Ykt6 YKT6 v-SNARE homolog (S. cerevisiae) multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr11:5,905,779...5,917,780
Ensembl chr11:5,905,693...5,917,780 		JBrowse link
carbon monoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases activity ISO Carbon Monoxide results in increased activity of ABCC2 protein CTD PMID:13678533 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein
[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased expression of PECAM1 protein; Carbon Monoxide results in increased expression of ADIPOQ protein		 CTD PMID:19356108 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin increases expression ISO Carbon Monoxide results in increased expression of ADM mRNA; Carbon Monoxide results in increased expression of ADM protein CTD PMID:10666155 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Agr2 anterior gradient 2 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Agt angiotensinogen decreases response to substance EXP AGT protein results in decreased susceptibility to Carbon Monoxide CTD PMID:18174886 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
increases phosphorylation		 EXP
ISO		 AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein]; Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of AKT1 protein]
Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD PMID:17179207 PMID:18037988 PMID:18215737 PMID:18845810 PMID:19356108 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase increases activity
multiple interactions		 ISO Carbon Monoxide results in increased activity of ALAD protein
Carbon Monoxide inhibits the reaction [[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein]		 CTD PMID:1032310 PMID:6740708 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Areg amphiregulin multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 decreases phosphorylation EXP Carbon Monoxide results in decreased phosphorylation of BACH1 protein CTD PMID:18845810 NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein] CTD PMID:18037988 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b multiple interactions ISO BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
decreases expression		 ISO Carbon Monoxide results in decreased expression of and results in decreased secretion of BDNF protein
Carbon Monoxide results in decreased expression of BDNF mRNA		 CTD PMID:27113706 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity		 ISO [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; Carbon Monoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein; Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP3 mRNA]; tin protoporphyrin IX inhibits the reaction [Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]]
Carbon Monoxide results in increased expression of CASP3 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Carbon Monoxide results in increased activity of CASP3 protein		 CTD PMID:17173083 PMID:19356108 PMID:19520142 PMID:25562542 PMID:31268311 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 increases activity ISO Carbon Monoxide results in increased activity of CASP7 protein CTD PMID:25562542 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions		 ISO Carbon Monoxide results in increased activity of CASP8 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA		 CTD PMID:25562542 PMID:31268311 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases activity
increases expression
multiple interactions		 ISO Carbon Monoxide results in increased activity of CASP9 protein
Carbon Monoxide results in increased expression of CASP9 mRNA; Carbon Monoxide results in increased expression of CASP9 protein
sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 mRNA]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA		 CTD PMID:25562542 PMID:31268311 PMID:37860845 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions
decreases expression		 EXP
ISO		 CAT protein inhibits the reaction [Carbon Monoxide results in increased localization of NFE2L2 protein]; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of AKT1 protein]
Carbon Monoxide results in decreased expression of CAT protein
CAT protein inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to TFAM promoter]]; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NFE2L2 protein inhibits the reaction [Carbon Monoxide results in decreased expression of CAT protein]		 CTD PMID:17179207 PMID:18845810 PMID:34032369 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA CTD PMID:29621558 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516 		JBrowse link
G Cd86 CD86 antigen decreases expression ISO Carbon Monoxide results in decreased expression of CD86 protein CTD PMID:12201358 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA CTD PMID:29621558 NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537 		JBrowse link
G Col11a1 collagen, type XI, alpha 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA CTD PMID:29621558 NCBI chr 3:113,823,933...114,014,405
Ensembl chr 3:113,824,189...114,014,367 		JBrowse link
G Crp C-reactive protein, pentraxin-related increases expression ISO Carbon Monoxide results in increased expression of CRP protein CTD PMID:18629312 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA CTD PMID:29621558 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Carbon Monoxide inhibits the reaction [CYP1A1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP Carbon Monoxide promotes the reaction [1-ethynylpyrene results in increased expression of CYP1B1 mRNA] CTD PMID:10581206 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions		 ISO Carbon Monoxide results in decreased activity of CYP2E1 protein
Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]		 CTD PMID:1903091 PMID:15036350 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases expression		 ISO sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of DNM1L protein] CTD PMID:37860845 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Duox2 dual oxidase 2 decreases expression
increases expression		 ISO Carbon Monoxide results in decreased expression of DUOX2 protein
Carbon Monoxide results in increased expression of DUOX2 mRNA		 CTD PMID:29223502 NCBI chr 2:122,109,727...122,129,221
Ensembl chr 2:122,109,728...122,128,930 		JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions		 EXP
ISO		 Carbon Monoxide results in increased expression of EDN1 mRNA
Carbon Monoxide deficiency promotes the reaction [HMOX2 mutant form results in increased expression of EDN1 protein]
Carbon Monoxide results in increased expression of EDN1 mRNA; Carbon Monoxide results in increased expression of EDN1 protein		 CTD PMID:11781074 PMID:12969895 PMID:20197249 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]; UCP2 protein promotes the reaction [Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]] CTD PMID:22046279 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Eno2 enolase 2, gamma neuronal increases secretion ISO Carbon Monoxide results in increased secretion of ENO2 protein CTD PMID:34533065 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G Epo erythropoietin increases expression ISO Carbon Monoxide results in increased expression of EPO mRNA; Carbon Monoxide results in increased expression of EPO protein CTD PMID:9263988 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Carbon Monoxide results in increased expression of ERO1A mRNA CTD PMID:12752442 NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228 		JBrowse link
G Ezr ezrin multiple interactions ISO [[Vehicle Emissions results in increased abundance of Air Pollutants] which results in increased abundance of Carbon Monoxide] which results in decreased expression of EZR protein CTD PMID:37141245 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183 		JBrowse link
G Fgb fibrinogen beta chain multiple interactions