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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
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Accession:CHEBI:76838 term browser browse the term
Definition:An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
Synonyms:related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* inhibitor;   EC 1.14.14.* inhibitors


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1-aminobenzotriazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of ACAT1 protein] CTD PMID:32435916 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [Chlorpyrifos metabolite results in decreased activity of ACHE protein] CTD PMID:30625376 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACOT2 acyl-CoA thioesterase 2 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ACOT2 protein] CTD PMID:32435916 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658 		JBrowse link
G ALDH1B1 aldehyde dehydrogenase 1 family member B1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ALDH1B1 protein] CTD PMID:32435916 NCBI chr 9:38,392,702...38,398,661
Ensembl chr 9:38,392,702...38,398,661 		JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CAR3 protein] CTD PMID:32435916 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CD86 CD86 molecule multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CD86 protein] CTD PMID:21742781 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CES3 carboxylesterase 3 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CES3B protein] CTD PMID:32435916 NCBI chr16:66,961,266...66,975,149
Ensembl chr16:66,961,245...66,975,149 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression		 ISO
EXP		 1-aminobenzotriazole inhibits the reaction [Oxygen results in increased activity of CYP1A1 protein]; [1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A1 protein
1-aminobenzotriazole results in increased expression of CYP1A1 protein
1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]		 CTD PMID:10640292 PMID:20187624 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression
decreases activity
multiple interactions		 ISO
EXP		 1-aminobenzotriazole results in increased expression of CYP1A2 protein
1-aminobenzotriazole results in decreased activity of CYP1A2 protein
[1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A2 protein; [Oxygen co-treated with 1-aminobenzotriazole] results in increased expression of CYP1A2 protein		 CTD PMID:10640292 PMID:15618748 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 multiple interactions
decreases activity		 EXP 1-aminobenzotriazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]
1-aminobenzotriazole results in decreased activity of CYP2C9 protein		 CTD PMID:11375247 PMID:15618748 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) multiple interactions
decreases activity		 EXP 1-aminobenzotriazole inhibits the reaction [CYP2D6 protein results in increased hydroxylation of bufuralol]
1-aminobenzotriazole results in decreased activity of CYP2D6 protein		 CTD PMID:11375247 PMID:15618748 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions
decreases activity		 EXP
ISO		 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]
1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]; 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]
1-aminobenzotriazole results in decreased activity of CYP2E1 protein		 CTD PMID:10828257 PMID:12704224 PMID:15618748 PMID:25243916 PMID:27421776 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity EXP 1-aminobenzotriazole results in decreased activity of CYP3A4 protein CTD PMID:11375247 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] CTD PMID:24555085 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G ECH1 enoyl-CoA hydratase 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ECH1 protein] CTD PMID:32435916 NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841 		JBrowse link
G FTCD formimidoyltransferase cyclodeaminase multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of FTCD protein] CTD PMID:32435916 NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579 		JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased expression of FTH1 protein] CTD PMID:32435916 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G FTL ferritin light chain multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of FTL1 protein] CTD PMID:32435916 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,967,896 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; 1-aminobenzotriazole inhibits the reaction [Acetaminophen results in increased expression of GPT protein]; 1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [1-aminobenzotriazole co-treated with ochratoxin A] results in increased activity of GPT protein; [Emodin co-treated with 1-aminobenzotriazole] results in increased expression of GPT protein CTD PMID:25900201 PMID:34492313 PMID:36227364 PMID:38825056 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of GSTM1 protein] CTD PMID:32435916 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein] CTD PMID:28300663 PMID:29722447 PMID:35279910 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 multiple interactions ISO [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of HAVCR1 protein CTD PMID:36227364 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [[Acetaminophen co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Butylated Hydroxyanisole co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Diclofenac co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Ticlopidine co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA] CTD PMID:18227147 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G INMT indolethylamine N-methyltransferase multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of INMT protein] CTD PMID:32435916 NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602 		JBrowse link
G KRT8 keratin 8 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of KRT8 protein] CTD PMID:32435916 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LCN2 lipocalin 2 multiple interactions ISO [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of LCN2 protein CTD PMID:36227364 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G RGN regucalcin multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of RGN protein] CTD PMID:32435916 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 multiple interactions EXP 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G UBP1 upstream binding protein 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of UBP1 protein] CTD PMID:32435916 NCBI chr 3:33,388,336...33,441,399
Ensembl chr 3:33,388,336...33,441,371 		JBrowse link
1-phenylimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:7710944 PMID:21842885 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
3,3'-diindolylmethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression
multiple interactions		 EXP 3,3'-diindolylmethane results in increased expression of ABCB1 mRNA
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]		 CTD PMID:25542144 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACTG1 actin gamma 1 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of ACTG1 mRNA] CTD PMID:11179685 NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847 		JBrowse link
G ADGRE1 adhesion G protein-coupled receptor E1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of ADGRE1 mRNA] CTD PMID:24162184 NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459 		JBrowse link
G AHR aryl hydrocarbon receptor affects response to substance
affects localization
multiple interactions		 EXP
ISO		 AHR protein affects the susceptibility to 3,3'-diindolylmethane
3,3'-diindolylmethane affects the localization of AHR protein
3,3'-diindolylmethane binds to and results in decreased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]		 CTD PMID:8384853 PMID:9771935 PMID:11294972 PMID:16972788 PMID:19056653 More... NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of AIF1 protein] CTD PMID:24162184 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AR androgen receptor decreases activity EXP 3,3'-diindolylmethane results in decreased activity of AR protein CTD PMID:30247711 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter] CTD PMID:16972788 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ATF3 activating transcription factor 3 increases expression EXP 3,3'-diindolylmethane results in increased expression of ATF3 CTD PMID:15670751 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of ATP5F1A mRNA] CTD PMID:11179685 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G BAD BCL2 associated agonist of cell death decreases phosphorylation EXP 3,3'-diindolylmethane results in decreased phosphorylation of BAD protein CTD PMID:22290291 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP 3,3'-diindolylmethane results in increased expression of BAX protein CTD PMID:22290291 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions EXP [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 CTD PMID:22290291 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP
ISO		 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]
3,3'-diindolylmethane analog results in decreased expression of BCL2 mRNA
3,3'-diindolylmethane analog results in decreased expression of BCL2 protein; 3,3'-diindolylmethane results in decreased expression of BCL2 protein		 CTD PMID:16051428 PMID:16580691 PMID:22290291 PMID:26593444 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 increases expression EXP 3,3'-diindolylmethane results in increased expression of BCL2L1 mRNA; 3,3'-diindolylmethane results in increased expression of BCL2L1 protein CTD PMID:18025290 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L10 BCL2 like 10 increases expression EXP 3,3'-diindolylmethane results in increased expression of BCL2L10 mRNA CTD PMID:22514694 NCBI chr15:52,109,263...52,112,775
Ensembl chr15:52,109,263...52,112,775 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of BIRC5 protein CTD PMID:22290291 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BRD2 bromodomain containing 2 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA] CTD PMID:11179685 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505 		JBrowse link
G CALM2 calmodulin 2 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CALM2 mRNA] CTD PMID:11179685 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921 		JBrowse link
G CASP3 caspase 3 increases activity ISO 3,3'-diindolylmethane results in increased activity of CASP3 protein CTD PMID:21820497 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CCN1 cellular communication network factor 1 affects methylation EXP 3,3'-diindolylmethane affects the methylation of CCN1 promoter CTD PMID:24466240 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CCNB1 CTD PMID:22290291 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions		 EXP 3,3'-diindolylmethane analog results in decreased expression of CCND1 protein; 3,3'-diindolylmethane results in decreased expression of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]		 CTD PMID:16051428 PMID:22290291 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND3 cyclin D3 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CCND3 protein CTD PMID:22514694 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 affects methylation EXP 3,3'-diindolylmethane affects the methylation of CCR4 promoter CTD PMID:24466240 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120 		JBrowse link
G CD40LG CD40 ligand increases expression EXP 3,3'-diindolylmethane results in increased expression of CD40LG mRNA CTD PMID:22514694 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD69 CD69 molecule multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of CD69 protein] CTD PMID:24200994 NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901 		JBrowse link
G CDC25C cell division cycle 25C decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CDC25C CTD PMID:22290291 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDH1 cadherin 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in decreased expression of CDH1 protein] CTD PMID:28844962 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH11 cadherin 11 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CDH11 protein CTD PMID:18025290 NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112 		JBrowse link
G CDH2 cadherin 2 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CDH2 protein] CTD PMID:28844962 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions
decreases activity		 EXP 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in decreased activity of CDK2 protein		 CTD PMID:15611077 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CDK4 protein CTD PMID:22514694 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of CDK6 protein CTD PMID:22290291 PMID:22514694 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression		 EXP 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in increased expression of CDKN1A mRNA; 3,3'-diindolylmethane results in increased expression of CDKN1A protein		 CTD PMID:12203118 PMID:15611077 PMID:18025290 PMID:22290291 PMID:22495798 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B increases expression EXP 3,3'-diindolylmethane results in increased expression of CDKN1B protein CTD PMID:22290291 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D increases expression EXP 3,3'-diindolylmethane results in increased expression of CDKN2D protein CTD PMID:22290291 NCBI chr19:10,566,460...10,568,979
Ensembl chr19:10,566,460...10,569,059 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex decreases phosphorylation EXP 3,3'-diindolylmethane results in decreased phosphorylation of CHUK protein CTD PMID:22290291 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CKS1B CDC28 protein kinase regulatory subunit 1B multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CKS1B mRNA] CTD PMID:11179685 NCBI chr 1:154,974,681...154,979,251
Ensembl chr 1:154,974,653...154,979,251 		JBrowse link
G CTSB cathepsin B multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSB protein] CTD PMID:28844962 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSD protein] CTD PMID:28844962 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 affects methylation
multiple interactions		 EXP 3,3'-diindolylmethane affects the methylation of CXCR4 promoter
3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CXCR4 protein]		 CTD PMID:24466240 PMID:28844962 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP 3,3'-diindolylmethane analog affects the localization of and results in increased expression of CYCS protein CTD PMID:16051428 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 increases expression EXP 3,3'-diindolylmethane analog results in increased expression of CYP19A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP19A1 mRNA CTD PMID:11294972 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
increases activity
increases expression
multiple interactions		 EXP
ISO		 3,3'-diindolylmethane results in decreased activity of CYP1A1 protein
3,3'-diindolylmethane analog results in increased activity of CYP1A1 protein; 3,3'-diindolylmethane results in increased activity of CYP1A1 protein
3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane analog results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; [3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct		 CTD PMID:8384853 PMID:9771935 PMID:11179685 PMID:11294972 PMID:11597580 More... NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions
increases expression
decreases activity
increases oxidation		 EXP
ISO		 [3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct; Quercetin inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]; resveratrol inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]
3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in decreased activity of CYP1A2 protein		 CTD PMID:8384853 PMID:15672752 PMID:16544949 PMID:19770484 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression EXP 3,3'-diindolylmethane analog results in increased expression of CYP1B1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1B1 mRNA CTD PMID:11294972 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity
multiple interactions
increases expression		 EXP 3,3'-diindolylmethane results in decreased activity of CYP3A4 protein
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of CYP3A4 mRNA]		 CTD PMID:19770484 PMID:25542144 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP 3,3'-diindolylmethane results in increased expression of DDIT3 protein CTD PMID:22290291 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DNMT1 DNA methyltransferase 1 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases expression EXP 3,3'-diindolylmethane results in decreased expression of DNMT3B mRNA CTD PMID:24466240 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G EEF1G eukaryotic translation elongation factor 1 gamma multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of EEF1G mRNA] CTD PMID:11179685 NCBI chr11:62,559,596...62,573,891
Ensembl chr11:62,559,596...62,574,086 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of ERBB2 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of ERBB2 protein CTD PMID:16580691 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
decreases expression		 EXP 3,3'-diindolylmethane binds to and results in increased activity of ESR1 protein; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]
3,3'-diindolylmethane results in decreased expression of ESR1		 CTD PMID:16972788 PMID:19223575 PMID:23583297 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions
increases expression		 EXP 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Tamoxifen inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA] CTD PMID:20160136 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAU FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of FAU mRNA] CTD PMID:11179685 NCBI chr11:65,120,630...65,122,134
Ensembl chr11:65,120,630...65,122,177 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP 3,3'-diindolylmethane results in increased expression of GDF15 mRNA CTD PMID:15670751 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GNAS GNAS complex locus multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA] CTD PMID:11179685 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GREB1 growth regulating estrogen receptor binding 1 increases expression EXP 3,3'-diindolylmethane results in increased expression of GREB1 mRNA CTD PMID:23583297 NCBI chr 2:11,482,888...11,642,788
Ensembl chr 2:11,482,341...11,642,788 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases phosphorylation EXP 3,3'-diindolylmethane results in decreased phosphorylation of GSK3B protein CTD PMID:22290291 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions
decreases expression		 EXP [3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct CTD PMID:19770484 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G H3-3A H3.3 histone A multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of H3-3A mRNA] CTD PMID:11179685 NCBI chr 1:226,061,831...226,072,019
Ensembl chr 1:226,061,851...226,072,019 		JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC1 mRNA] CTD PMID:24200994 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC10 histone deacetylase 10 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC10 mRNA] CTD PMID:24200994 NCBI chr22:50,245,183...50,251,265
Ensembl chr22:50,245,183...50,251,405 		JBrowse link
G HDAC2 histone deacetylase 2 decreases expression
multiple interactions		 EXP
ISO		 3,3'-diindolylmethane results in decreased expression of HDAC2 protein
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC2 mRNA]		 CTD PMID:22800507 PMID:24200994 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC5 histone deacetylase 5 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC5 mRNA] CTD PMID:24200994 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G HDAC8 histone deacetylase 8 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC8 mRNA] CTD PMID:24200994 NCBI chr  X:72,329,516...72,572,843
Ensembl chr  X:72,329,516...72,573,101 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]] CTD PMID:23583297 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HRK harakiri, BCL2 interacting protein increases expression EXP 3,3'-diindolylmethane results in increased expression of HRK mRNA CTD PMID:22514694 NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions		 EXP 3,3'-diindolylmethane analog results in decreased expression of HSPA5 protein
3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]		 CTD PMID:25794856 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of HSPB1 mRNA] CTD PMID:11179685 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G IFNG interferon gamma multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IFNG protein] CTD PMID:24200994 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL2 interleukin 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL2 protein] CTD PMID:24200994 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 EXP
ISO		 3,3'-diindolylmethane results in increased expression of IL6 mRNA
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL6 protein]		 CTD PMID:18025290 PMID:24200994 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KDR kinase insert domain receptor decreases expression EXP 3,3'-diindolylmethane analog results in decreased expression of KDR protein CTD PMID:25794856 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KLF10 KLF transcription factor 10 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of KLF10 mRNA] CTD PMID:11179685 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725 		JBrowse link
G KLK3 kallikrein related peptidase 3 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of KLK3 mRNA CTD PMID:22495798 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764 		JBrowse link
G KRT18 keratin 18 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA] CTD PMID:11179685 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT19 keratin 19 multiple interactions
increases expression		 EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT19 mRNA]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA] CTD PMID:11179685 PMID:20160136 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G MAGEA9 MAGE family member A9 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MAGEA9 mRNA] CTD PMID:11179685 NCBI chr  X:149,781,877...149,787,737
Ensembl chr  X:149,781,930...149,787,737
Ensembl chr  X:149,781,930...149,787,737 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK1 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:16580691 PMID:22290291 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation
multiple interactions		 EXP 3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK3 protein		 CTD PMID:16580691 PMID:22290291 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MDM2 MDM2 proto-oncogene decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of MDM2 mRNA CTD PMID:26593444 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP2 protein] CTD PMID:28844962 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP 3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]; 3,3'-diindolylmethane analog results in decreased expression of and results in decreased activity of MMP9 protein; 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP9 protein] CTD PMID:25794856 PMID:28844962 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of COX2 mRNA] CTD PMID:11179685 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269 		JBrowse link
G MYB MYB proto-oncogene, transcription factor decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of MYB mRNA CTD PMID:26593444 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP
ISO		 3,3'-diindolylmethane results in decreased expression of MYC protein
3,3'-diindolylmethane analog results in decreased expression of MYC mRNA		 CTD PMID:22290291 PMID:26593444 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYL6 myosin light chain 6 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MYL6 mRNA] CTD PMID:11179685 NCBI chr12:56,158,359...56,161,579
Ensembl chr12:56,158,346...56,163,496 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 EXP 3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA; 3,3'-diindolylmethane results in increased expression of NFE2L2 protein
sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA]; sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 protein]		 CTD PMID:23583297 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:24162184 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression		 EXP 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]
3,3'-diindolylmethane results in increased expression of NQO1 mRNA		 CTD PMID:15672752 PMID:22495798 PMID:23583297 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity
multiple interactions		 EXP 3,3'-diindolylmethane results in increased activity of NR1I2 protein
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:25542144 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of NUMA1 protein] CTD PMID:26251508 NCBI chr11:72,002,864...72,080,542
Ensembl chr11:72,002,864...72,080,693 		JBrowse link
G NUP133 nucleoporin 133 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of NUP133 mRNA] CTD PMID:11179685 NCBI chr 1:229,440,259...229,508,341
Ensembl chr 1:229,440,259...229,508,341 		JBrowse link
G PAPOLA poly(A) polymerase alpha multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of PAPOLA mRNA] CTD PMID:11179685 NCBI chr14:96,502,376...96,567,116
Ensembl chr14:96,501,433...96,567,116 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP [3,3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:16580691 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP 3,3'-diindolylmethane results in increased expression of PLAU mRNA CTD PMID:18025290 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions EXP [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1 CTD PMID:22290291 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in decreased expression of PTEN protein] CTD PMID:26251508 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 EXP
ISO		 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 protein]
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of PTGS2 protein]
3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
3,3'-diindolylmethane results in decreased expression of PTGS2 mRNA; 3,3'-diindolylmethane results in decreased expression of PTGS2 protein		 CTD PMID:19056653 PMID:22290291 PMID:24162184 PMID:26251508 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions		 EXP
ISO		 3,3'-diindolylmethane results in decreased expression of RELA protein
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased phosphorylation of RELA protein]		 CTD PMID:22290291 PMID:26251508 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIBC1 RIB43A domain with coiled-coils 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RIBC1 mRNA] CTD PMID:11179685 NCBI chr  X:53,422,873...53,431,115
Ensembl chr  X:53,422,690...53,431,120 		JBrowse link
G RNA28SN4 RNA, 28S ribosomal N4 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RNA28SN4 mRNA] CTD PMID:11179685
G RPL10 ribosomal protein L10 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]; 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL10 mRNA] CTD PMID:11179685 NCBI chr  X:154,398,065...154,402,339
Ensembl chr  X:154,389,955...154,409,168 		JBrowse link
G RPL13A ribosomal protein L13a multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL13A mRNA] CTD PMID:11179685 NCBI chr19:49,487,608...49,492,308
Ensembl chr19:49,487,510...49,493,057 		JBrowse link
G RPL31 ribosomal protein L31 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL31 mRNA] CTD PMID:11179685 NCBI chr 2:101,002,289...101,019,724
Ensembl chr 2:101,002,229...101,024,032 		JBrowse link
G RPL41 ribosomal protein L41 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPL41 mRNA] CTD PMID:11179685 NCBI chr12:56,116,633...56,117,967
Ensembl chr12:56,116,590...56,117,967 		JBrowse link
G RPL7 ribosomal protein L7 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL7 mRNA] CTD PMID:11179685 NCBI chr 8:73,290,242...73,294,466
Ensembl chr 8:73,290,242...73,295,789 		JBrowse link
G RPLP0 ribosomal protein lateral stalk subunit P0 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPLP0 mRNA] CTD PMID:11179685 NCBI chr12:120,196,699...120,201,111
Ensembl chr12:120,196,699...120,201,235 		JBrowse link
G RPS15A ribosomal protein S15a multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS15A mRNA] CTD PMID:11179685 NCBI chr16:18,781,295...18,790,334
Ensembl chr16:18,781,295...18,790,383 		JBrowse link
G RPS17 ribosomal protein S17 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS17 mRNA] CTD PMID:11179685 NCBI chr15:82,536,750...82,540,457
Ensembl chr15:82,536,750...82,540,459 		JBrowse link
G RPS3 ribosomal protein S3 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPS3 mRNA] CTD PMID:11179685 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280 		JBrowse link
G RPS4X ribosomal protein S4 X-linked multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS4X mRNA] CTD PMID:11179685 NCBI chr  X:72,272,042...72,277,248
Ensembl chr  X:72,255,679...72,277,248 		JBrowse link
G RPS6 ribosomal protein S6 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS6 mRNA] CTD PMID:11179685 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI1 protein] CTD PMID:28844962 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI2 protein] CTD PMID:28844962 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G TFF1 trefoil factor 1 multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter] CTD PMID:16972788 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 affects methylation EXP 3,3'-diindolylmethane affects the methylation of TGFBR1 promoter CTD PMID:24466240 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP 3,3'-diindolylmethane analog results in increased expression of TIMP1 protein CTD PMID:25794856 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TMEM121B transmembrane protein 121B multiple interactions
increases expression		 EXP 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr22:17,116,297...17,121,360
Ensembl chr22:17,116,297...17,121,367 		JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions		 EXP
ISO		 3,3'-diindolylmethane results in decreased expression of TNF mRNA
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of TNF protein]
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of TNF protein]		 CTD PMID:22514694 PMID:24200994 PMID:26251508 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression EXP 3,3'-diindolylmethane results in increased expression of TNFRSF1A mRNA CTD PMID:22514694 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF25 TNF receptor superfamily member 25 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of TNFRSF25 mRNA CTD PMID:22514694 NCBI chr 1:6,460,786...6,466,173
Ensembl chr 1:6,460,786...6,466,175 		JBrowse link
G TNFSF8 TNF superfamily member 8 increases expression EXP 3,3'-diindolylmethane results in increased expression of TNFSF8 mRNA CTD PMID:22514694 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP 3,3'-diindolylmethane results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1; wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein] CTD PMID:22290291 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRAF4 TNF receptor associated factor 4 decreases expression EXP 3,3'-diindolylmethane results in decreased expression of TRAF4 mRNA CTD PMID:22514694 NCBI chr17:28,744,011...28,750,956
Ensembl chr17:28,744,011...28,750,956 		JBrowse link
G TYMS thymidylate synthetase multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of TYMS mRNA] CTD PMID:11179685 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G UBB ubiquitin B multiple interactions EXP 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of UBB mRNA] CTD PMID:11179685 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745 		JBrowse link
G XIAP X-linked inhibitor of apoptosis decreases expression EXP 3,3'-diindolylmethane results in decreased expression of XIAP protein CTD PMID:22290291 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 multiple interactions EXP 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of XRCC6 mRNA] CTD PMID:11179685 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048 		JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
alpha-naphthoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 multiple interactions ISO [alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter] CTD PMID:29094188 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G AHR aryl hydrocarbon receptor affects binding
decreases activity
multiple interactions		 EXP
ISO		 [alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein; [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein; [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein; alpha-naphthoflavone binds to AHR protein
alpha-naphthoflavone results in decreased activity of AHR protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein]; AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of AHR mRNA]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Benzo(a)pyrene; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Hexachlorobenzene; [alpha-naphthoflavone results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased abundance of Reactive Oxygen Species]; alpha-naphthoflavone analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Oxygen deficiency co-treated with Tetrachlorodibenzodioxin] results in decreased stability of AHR protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]; alpha-naphthoflavone inhibits the reaction [AHR protein binds to and results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]		 CTD PMID:1329656 PMID:7669069 PMID:8390116 PMID:8738555 PMID:9006915 More... NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases methylation
multiple interactions		 ISO alpha-naphthoflavone results in increased methylation of AKT1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA]		 CTD PMID:29094188 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AR androgen receptor multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of AR protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]
alpha-naphthoflavone results in increased expression of AR protein		 CTD PMID:12970580 PMID:15041469 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions EXP
ISO		 alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]
ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]		 CTD PMID:11768231 PMID:21127131 PMID:30508555 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of BAX mRNA]
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]		 CTD PMID:20562217 PMID:29094188 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BMP15 bone morphogenetic protein 15 multiple interactions ISO [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA CTD PMID:29094188 NCBI chr  X:50,910,735...50,916,641
Ensembl chr  X:50,910,735...50,916,641 		JBrowse link
G BPGM bisphosphoglycerate mutase multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]
alpha-naphthoflavone results in increased expression of BPGM mRNA		 CTD PMID:23152189 NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816 		JBrowse link
G BRCA1 BRCA1 DNA repair associated multiple interactions EXP alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA] CTD PMID:16489025 PMID:18259752 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G CALR calreticulin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA] CTD PMID:29094188 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) increases cleavage ISO alpha-naphthoflavone results in increased cleavage of CASP12 protein CTD PMID:30508555 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions
increases cleavage
decreases activity		 ISO alpha-naphthoflavone results in increased activity of CASP3 protein
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased cleavage of CASP3 protein]
alpha-naphthoflavone results in increased cleavage of CASP3 protein
alpha-naphthoflavone results in decreased activity of CASP3 protein		 CTD PMID:15710172 PMID:18334599 PMID:30508555 PMID:35908932 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases activity ISO alpha-naphthoflavone results in increased activity of CASP8 protein CTD PMID:18334599 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases activity
multiple interactions		 ISO alpha-naphthoflavone results in increased activity of CASP9 protein
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]		 CTD PMID:18334599 PMID:29094188 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein] CTD PMID:20600218 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CCL1] CTD PMID:16679317 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression
increases expression
multiple interactions		 EXP alpha-naphthoflavone results in decreased expression of CCL2 mRNA
alpha-naphthoflavone results in increased expression of CCL2 mRNA
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL2 mRNA]		 CTD PMID:22262711 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCNB1 cyclin B1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA] CTD PMID:25051199 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of CCND1 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of CCND1 protein] CTD PMID:31364906 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD9 CD9 molecule multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA] CTD PMID:29094188 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CDC25C cell division cycle 25C multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CDC25C mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDC25C protein] CTD PMID:22266097 PMID:25051199 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDH1 cadherin 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in decreased expression of CDH1 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in decreased expression of CDH1 protein] CTD PMID:31364906 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH13 cadherin 13 multiple interactions ISO AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH13 mRNA] CTD PMID:12559965 NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640 		JBrowse link
G CDK1 cyclin dependent kinase 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDK1 protein] CTD PMID:22266097 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of CDK2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]		 CTD PMID:29094188 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [eupatorin-5-methyl ether results in increased expression of CDKN1A protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein] CTD PMID:21887816 PMID:22266097 PMID:23994263 PMID:24361490 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1B protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDKN1B protein] CTD PMID:15157999 PMID:22266097 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta multiple interactions EXP alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of CEBPD mRNA] CTD PMID:21652769 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164 		JBrowse link
G CGB3 chorionic gonadotropin subunit beta 3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CGB3 mRNA] CTD PMID:24361490 NCBI chr19:49,022,869...49,024,333
Ensembl chr19:49,022,869...49,024,333 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CTSD cathepsin D multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]] CTD PMID:11165043 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
decreases expression
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA]
alpha-naphthoflavone results in decreased expression of CXCL8 mRNA
alpha-naphthoflavone results in increased expression of CXCL8 mRNA		 CTD PMID:22262711 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYGB cytoglobin multiple interactions EXP alpha-naphthoflavone inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] CTD PMID:25781201 NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 multiple interactions
increases expression		 EXP alpha-naphthoflavone promotes the reaction [CYP11B1 protein results in increased chemical synthesis of Hydrocortisone]
alpha-naphthoflavone results in increased expression of CYP11B1 mRNA		 CTD PMID:22172629 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression EXP alpha-naphthoflavone results in decreased expression of CYP17A1 mRNA CTD PMID:24875446 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions
increases expression		 EXP [alpha-naphthoflavone results in decreased activity of CYP19A1 protein] which results in decreased susceptibility to o,p'-DDT; alpha-naphthoflavone binds to and results in decreased activity of CYP19A1 protein; alpha-naphthoflavone inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein]
alpha-naphthoflavone results in increased expression of CYP19A1 protein		 CTD PMID:9435150 PMID:20678559 PMID:20823264 PMID:21296134 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases activity
affects binding
increases expression
multiple interactions
decreases activity		 EXP
ISO		 alpha-naphthoflavone results in increased activity of CYP1A1 protein
CYP1A1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A1 mRNA
alpha-naphthoflavone analog results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 protein
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [afimoxifene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Calcitriol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Resveratrol results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [STO 609 results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone results in decreased activity of CYP1A1 protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; [alpha-naphthoflavone results in decreased activity of CYP1A1 protein] inhibits the reaction [Vinyl Compounds analog results in decreased susceptibility to sodium arsenite]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [norisoboldine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone analog results in increased activity of CYP1A1 protein		 CTD PMID:1329656 PMID:6477826 PMID:7669069 PMID:8390116 PMID:8637871 More... NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions
affects binding
increases expression
increases metabolic processing
affects metabolic processing
decreases activity		 EXP
ISO		 [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin; alpha-naphthoflavone binds to and results in decreased activity of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A2 protein
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with alpha-naphthoflavone] results in increased expression of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde
CYP1A2 protein results in increased metabolism of alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A2 mRNA; alpha-naphthoflavone results in increased expression of CYP1A2 protein
CYP1A2 protein affects the metabolism of alpha-naphthoflavone		 CTD PMID:2180560 PMID:9305587 PMID:15306208 PMID:15766918 PMID:15860655 More... NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 multiple interactions
affects binding
increases metabolic processing
increases expression
decreases expression
decreases activity		 EXP
ISO		 alpha-naphthoflavone binds to and results in decreased activity of CYP1B1 protein; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]; alpha-naphthoflavone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CYP1B1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
CYP1B1 protein results in increased metabolism of alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein]; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]
alpha-naphthoflavone results in increased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased activity of CYP1B1 protein		 CTD PMID:11577022 PMID:15075337 PMID:15280921 PMID:16120791 PMID:19182260 More... NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]] CTD PMID:19244278 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA] CTD PMID:18467041 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 multiple interactions EXP [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 decreases activity EXP alpha-naphthoflavone results in decreased activity of CYP2J2 protein CTD PMID:12851038 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
increases activity
decreases activity
affects binding		 EXP [[alpha-naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [alpha-naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; alpha-naphthoflavone binds to and results in decreased activity of CYP3A4 protein; alpha-naphthoflavone inhibits the reaction [CYP3A4 protein results in increased hydrolysis of Testosterone]; alpha-naphthoflavone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; alpha-naphthoflavone inhibits the reaction [CYP3A4 protein results in increased oxidation of Methylenebis(chloroaniline)]
alpha-naphthoflavone results in decreased activity of CYP3A4 protein
alpha-naphthoflavone binds to CYP3A4 protein		 CTD PMID:1740010 PMID:2271712 PMID:15005856 PMID:17198380 PMID:19299527 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DAZL deleted in azoospermia like multiple interactions EXP alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA] CTD PMID:20562217 NCBI chr 3:16,586,792...16,605,423
Ensembl chr 3:16,586,792...16,670,306 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions		 ISO alpha-naphthoflavone results in increased expression of DDIT3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; pyrazolanthrone inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SB 203580 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]		 CTD PMID:30508555 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA] CTD PMID:29094188 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DDX4 DEAD-box helicase 4 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA] CTD PMID:20562217 NCBI chr 5:55,738,061...55,817,157
Ensembl chr 5:55,738,017...55,817,157 		JBrowse link
G DDX5 DEAD-box helicase 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA] CTD PMID:29094188 NCBI chr17:64,498,254...64,506,866
Ensembl chr17:64,498,254...64,508,199 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA] CTD PMID:29094188 NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of DNAJB6 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]		 CTD PMID:29094188 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439 		JBrowse link
G DUSP5 dual specificity phosphatase 5 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein] CTD PMID:19578757 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EGLN1 mRNA] CTD PMID:18072750 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO alpha-naphthoflavone results in increased phosphorylation of EIF2S1 protein CTD PMID:30508555 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G ENO1 enolase 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENO1 mRNA] CTD PMID:23152189 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Oxygen deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA] CTD PMID:19028555 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453 		JBrowse link
G ERVFRD-1 endogenous retrovirus group FRD member 1, envelope multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA] CTD PMID:24361490 NCBI chr 6:11,102,489...11,111,725
Ensembl chr 6:11,102,324...11,111,845 		JBrowse link
G ESR1 estrogen receptor 1 affects binding
multiple interactions		 EXP
ISO		 [alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of ESR1 protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Estradiol binds to ESR1 protein]]
[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA]		 CTD PMID:10620335 PMID:15253042 PMID:22975028 PMID:29094188 PMID:35181438 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA CTD PMID:22975028 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G ESRRA estrogen related receptor alpha affects binding EXP [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein CTD PMID:10620335 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FAS mRNA] CTD PMID:16940415 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FASL mRNA] CTD PMID:16940415 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:20876236 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FLG filaggrin multiple interactions EXP [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA] CTD PMID:21835898 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of FOS mRNA]] CTD PMID:10478842 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOXN3 forkhead box N3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA] CTD PMID:29094188 NCBI chr14:89,156,177...89,619,165
Ensembl chr14:89,124,871...89,619,149 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions EXP
ISO		 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of FOXO3 protein]
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA		 CTD PMID:22266097 PMID:29094188 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FOXP3 forkhead box P3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of FOXP3 mRNA] CTD PMID:26640276 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FSHR follicle stimulating hormone receptor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FSHR protein] CTD PMID:20823264 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527 		JBrowse link
G GDF9 growth differentiation factor 9 increases expression
multiple interactions		 ISO alpha-naphthoflavone results in increased expression of GDF9 mRNA
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA		 CTD PMID:29094188 NCBI chr 5:132,861,185...132,866,651
Ensembl chr 5:132,861,181...132,866,884 		JBrowse link
G GPI glucose-6-phosphate isomerase multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GPI mRNA]
alpha-naphthoflavone results in increased expression of GPI mRNA		 CTD PMID:23152189 NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSR mRNA] CTD PMID:23152189 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression EXP alpha-naphthoflavone results in decreased expression of GSTP1 mRNA CTD PMID:18762178 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA] CTD PMID:29094188 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of HIF1A protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of HIF1A protein] CTD PMID:38844257 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK1 hexokinase 1 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HK1 mRNA]
alpha-naphthoflavone results in increased expression of HK1 mRNA		 CTD PMID:23152189 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR protein] CTD PMID:19931295 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA] CTD PMID:29094188 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA] CTD PMID:26519956 PMID:29094188 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IGF2 insulin like growth factor 2 decreases acetylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased acetylation of IGF2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]		 CTD PMID:29094188 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 multiple interactions
increases expression		 ISO AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein] CTD PMID:23639626 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO
EXP		 [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of IL10 mRNA]
alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 protein]		 CTD PMID:11737050 PMID:17681673 PMID:26640276 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
decreases expression		 EXP
ISO		 alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B protein]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]
alpha-naphthoflavone results in increased expression of IL1B mRNA
alpha-naphthoflavone results in decreased expression of IL1B mRNA		 CTD PMID:14993811 PMID:15019843 PMID:18617548 PMID:21127131 PMID:22262711 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1RN mRNA]
alpha-naphthoflavone results in increased expression of IL1RN mRNA		 CTD PMID:22262711 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 EXP
ISO		 alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]
alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]
alpha-naphthoflavone results in increased expression of IL6 mRNA		 CTD PMID:21162728 PMID:26519956 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGB8 integrin subunit beta 8 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA] CTD PMID:29094188 NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 decreases methylation
multiple interactions		 ISO alpha-naphthoflavone results in decreased methylation of JAG1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]		 CTD PMID:29094188 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP
ISO		 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of JUN protein]
alpha-naphthoflavone results in increased expression of JUN mRNA		 CTD PMID:15019843 PMID:15897893 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KLK3 kallikrein related peptidase 3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]]; alpha-naphthoflavone inhibits the reaction [benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]]; alpha-naphthoflavone inhibits the reaction [benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]]; alpha-naphthoflavone inhibits the reaction [chrysene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]]; alpha-naphthoflavone inhibits the reaction [chrysene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]] CTD PMID:12799773 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764 		JBrowse link
G KRT14 keratin 14 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of KRT14 mRNA] CTD PMID:25051199 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LDHA mRNA]
alpha-naphthoflavone results in increased expression of LDHA mRNA		 CTD PMID:23152189 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LHCGR protein] CTD PMID:20823264 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP
ISO		 [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK1 protein]
alpha-naphthoflavone results in increased phosphorylation of MAPK1 protein
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK1 protein]		 CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP
ISO		 [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK3 protein]
alpha-naphthoflavone results in increased phosphorylation of MAPK3 protein
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK3 protein]		 CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MDM2 MDM2 proto-oncogene multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA] CTD PMID:19578757 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA]
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]		 CTD PMID:15075337 PMID:19022365 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP2 mRNA]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP2 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP2 protein]		 CTD PMID:19022365 PMID:31364906 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP3 mRNA] CTD PMID:19022365 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP9 mRNA]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP9 mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MMP9 protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of and results in increased activity of MMP9 protein]		 CTD PMID:19022365 PMID:23462309 PMID:31364906 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT1X metallothionein 1X increases expression ISO alpha-naphthoflavone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of MTOR protein] CTD PMID:22266097 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein]
alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MYC mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of MYC protein]		 CTD PMID:22100782 PMID:31364906 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYOG myogenin multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYOG protein] CTD PMID:24431215 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NCF1 mRNA] CTD PMID:19559082 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS1 mRNA] CTD PMID:23152189 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS3 mRNA] CTD PMID:23152189 NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NFATC1 protein] CTD PMID:19028555 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]
alpha-naphthoflavone results in increased expression of NOS2 protein		 CTD PMID:26086121 PMID:33722737 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH2 notch receptor 2 multiple interactions
decreases acetylation
increases methylation		 ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]
alpha-naphthoflavone results in decreased acetylation of NOTCH2 promoter
alpha-naphthoflavone results in increased methylation of NOTCH2 promoter		 CTD PMID:29094188 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression		 ISO alpha-naphthoflavone results in increased activity of NQO1 protein
alpha-naphthoflavone results in increased expression of NQO1 mRNA		 CTD PMID:16906435 PMID:17069994 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases activity ISO alpha-naphthoflavone results in increased activity of NR1I3 protein CTD PMID:27732639 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 affects binding EXP [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein CTD PMID:10620335 NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage ISO alpha-naphthoflavone results in increased cleavage of PARP1 protein CTD PMID:30508555 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PFKM phosphofructokinase, muscle multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PFKM mRNA]
alpha-naphthoflavone results in increased expression of PFKM mRNA		 CTD PMID:23152189 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404 		JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGK1 mRNA]
alpha-naphthoflavone results in increased expression of PGK1 mRNA		 CTD PMID:23152189 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PGM1 phosphoglucomutase 1 increases expression
multiple interactions		 EXP alpha-naphthoflavone results in increased expression of PGM1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNA]		 CTD PMID:23152189 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245 		JBrowse link
G PGR progesterone receptor increases expression EXP alpha-naphthoflavone results in increased expression of PGR protein CTD PMID:22266097 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PKM pyruvate kinase M1/2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of PPARA protein] CTD PMID:21849270 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PRDM1 PR/SET domain 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA] CTD PMID:20562217 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G PRKCB protein kinase C beta multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of PRKCB protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of PRKCB protein] CTD PMID:16797713 PMID:17222441 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRL prolactin multiple interactions ISO alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of PRL mRNA] CTD PMID:22975028 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
increases expression		 EXP
ISO		 alpha-naphthoflavone results in decreased expression of PTGS2 mRNA
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone results in increased expression of PTGS2 mRNA		 CTD PMID:21162728 PMID:21652769 PMID:22262711 PMID:26358519 PMID:27393915 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein] CTD PMID:16359657 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RACK1 receptor for activated C kinase 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RACK1 protein] CTD PMID:16797713 PMID:17222441 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096 		JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] CTD PMID:15157999 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression		 EXP
ISO		 alpha-naphthoflavone inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]
alpha-naphthoflavone results in decreased expression of RELA protein		 CTD PMID:24431215 PMID:33722737 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SAA1 serum amyloid A1 multiple interactions EXP alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA] CTD PMID:21127131 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G SERPINB2 serpin family B member 2 multiple interactions
decreases expression
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]]
alpha-naphthoflavone results in decreased expression of SERPINB2 mRNA
alpha-naphthoflavone results in increased expression of SERPINB2 mRNA		 CTD PMID:15075337 PMID:22262711 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA]
alpha-naphthoflavone results in increased expression of SLC2A1 mRNA		 CTD PMID:23152189 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 protein] CTD PMID:26519956 NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174 		JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] CTD PMID:27519288 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of SP1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of SP1 mRNA] CTD PMID:29094188 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase increases phosphorylation
multiple interactions		 ISO alpha-naphthoflavone results in increased phosphorylation of SRC protein
SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]		 CTD PMID:30508555 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B multiple interactions EXP [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein] CTD PMID:21205633 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G TCF7 transcription factor 7 increases expression EXP alpha-naphthoflavone results in increased expression of TCF7 mRNA CTD PMID:18762178 NCBI chr 5:134,108,218...134,148,210
Ensembl chr 5:134,114,681...134,151,865 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO
EXP		 alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of TGFB1 mRNA]
alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of TGFB1 mRNA]		 CTD PMID:22975028 PMID:27519288 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TIPARP TCDD inducible poly(ADP-ribose) polymerase decreases expression
multiple interactions		 EXP alpha-naphthoflavone results in decreased expression of TIPARP mRNA
alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of TIPARP mRNA]		 CTD PMID:18762178 PMID:21652769 NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP		 alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of TNF mRNA]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]		 CTD PMID:17934341 PMID:20801209 PMID:23099484 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions EXP alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1A protein] CTD PMID:34200499 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions EXP alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1B protein] CTD PMID:34200499 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]] CTD PMID:26221077 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]
alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]
alpha-naphthoflavone results in increased expression of TP53 protein
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of TRP53 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene affects the localization of TRP53 protein]		 CTD PMID:9006915 PMID:15459018 PMID:29274324 PMID:32553695 PMID:35908932 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TPI1 triosephosphate isomerase 1 increases expression
multiple interactions		 EXP alpha-naphthoflavone results in increased expression of TPI1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TPI1 mRNA]		 CTD PMID:23152189 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G VDR vitamin D receptor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]] CTD PMID:19244278 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions EXP
ISO		 alpha-naphthoflavone affects the reaction [Hexachlorobenzene results in increased expression of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA protein]; alpha-naphthoflavone promotes the reaction [Chlorpyrifos results in increased expression of VEGFA protein]
alpha-naphthoflavone inhibits the reaction [norisoboldine results in decreased expression of VEGFA mRNA]
alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]]		 CTD PMID:19182260 PMID:26221077 PMID:26358519 PMID:32526215 PMID:38844257 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin multiple interactions EXP alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of VIM mRNA]; alpha-naphthoflavone inhibits the reaction [4-hydroxyestradiol results in increased expression of VIM protein] CTD PMID:31364906 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WAPL WAPL cohesin release factor multiple interactions EXP alpha-naphthoflavone promotes the reaction [3-methylcholanthrylene results in increased expression of WAPL mRNA] CTD PMID:15797623 NCBI chr10:86,435,256...86,521,792
Ensembl chr10:86,435,256...86,521,792 		JBrowse link
amentoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions EXP amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein] CTD PMID:34599948 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:28185818 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein] CTD PMID:28185818 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO
EXP		 amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]		 CTD PMID:28185818 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form] CTD PMID:28185818 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions EXP amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 mRNA]; amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]] CTD PMID:34599948 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:28185818 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP amentoflavone results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DCT dopachrome tautomerase decreases expression EXP amentoflavone analog results in decreased expression of DCT mRNA; amentoflavone analog results in decreased expression of DCT protein CTD PMID:17473463 NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682 		JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] CTD PMID:28185818 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein] CTD PMID:28185818 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein] CTD PMID:28185818 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein] CTD PMID:28185818 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
multiple interactions		 EXP
ISO		 amentoflavone results in decreased expression of NOS2 protein
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]		 CTD PMID:12144868 PMID:28185818 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]] CTD PMID:34599948 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGDS prostaglandin D2 synthase affects binding EXP amentoflavone binds to PTGDS protein CTD PMID:26456343 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 EXP amentoflavone results in decreased expression of PTGS2 mRNA; amentoflavone results in decreased expression of PTGS2 protein
[amentoflavone results in decreased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone		 CTD PMID:12144868 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 decreases expression EXP amentoflavone results in decreased expression of SREBF1 mRNA CTD PMID:34599948 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:28185818 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TYR tyrosinase decreases activity EXP amentoflavone analog results in decreased activity of TYR protein CTD PMID:17473463 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 decreases activity EXP amentoflavone results in decreased activity of UGT1A1 protein CTD PMID:29470958 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 decreases activity EXP amentoflavone results in decreased activity of UGT1A10 protein CTD PMID:29470958 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 decreases activity EXP amentoflavone results in decreased activity of UGT1A3 protein CTD PMID:29470958 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A4 UDP glucuronosyltransferase family 1 member A4 decreases activity EXP amentoflavone results in decreased activity of UGT1A4 protein CTD PMID:29470958 NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 decreases activity
multiple interactions		 EXP amentoflavone results in decreased activity of UGT1A6 protein
amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol]		 CTD PMID:29470958 PMID:32421801 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300 		JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 decreases activity EXP amentoflavone results in decreased activity of UGT1A7 protein CTD PMID:29470958 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 decreases activity EXP amentoflavone results in decreased activity of UGT1A8 protein CTD PMID:29470958 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 decreases activity EXP amentoflavone results in decreased activity of UGT1A9 protein CTD PMID:29470958 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 decreases activity EXP amentoflavone results in decreased activity of UGT2B17 protein CTD PMID:29470958 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G UGT2B4 UDP glucuronosyltransferase family 2 member B4 decreases activity EXP amentoflavone results in decreased activity of UGT2B4 protein CTD PMID:29470958 NCBI chr 4:69,480,165...69,526,014
Ensembl chr 4:69,480,165...69,526,014 		JBrowse link
aminoglutethimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP1 acid phosphatase 1 decreases expression EXP Aminoglutethimide results in decreased expression of ACP1 protein CTD PMID:26102013 NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283 		JBrowse link
G ANP32B acidic nuclear phosphoprotein 32 family member B decreases expression EXP Aminoglutethimide results in decreased expression of ANP32B protein CTD PMID:26102013 NCBI chr 9:97,983,341...98,015,943
Ensembl chr 9:97,983,341...98,015,943 		JBrowse link
G BASP1 brain abundant membrane attached signal protein 1 decreases expression EXP Aminoglutethimide results in decreased expression of BASP1 protein CTD PMID:26102013 NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843 		JBrowse link
G BCAP31 B cell receptor associated protein 31 decreases expression EXP Aminoglutethimide results in decreased expression of BCAP31 protein CTD PMID:26102013 NCBI chr  X:153,700,492...153,724,387
Ensembl chr  X:153,700,492...153,724,565 		JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 increases expression EXP Aminoglutethimide results in increased expression of CCT4 protein CTD PMID:26102013 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671 		JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A decreases expression EXP Aminoglutethimide results in decreased expression of CCT6A protein CTD PMID:26102013 NCBI chr 7:56,051,765...56,063,989
Ensembl chr 7:56,051,685...56,063,989 		JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 decreases expression EXP Aminoglutethimide results in decreased expression of CCT7 protein CTD PMID:26102013 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021 		JBrowse link
G COMT catechol-O-methyltransferase increases expression EXP Aminoglutethimide results in increased expression of COMT protein CTD PMID:26102013 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CUTA cutA divalent cation tolerance homolog decreases expression EXP Aminoglutethimide results in decreased expression of CUTA protein CTD PMID:26102013 NCBI chr 6:33,416,442...33,418,107
Ensembl chr 6:33,416,442...33,418,317 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions EXP Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA] CTD PMID:16935330 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression EXP Aminoglutethimide results in decreased expression of CYP17A1 mRNA CTD PMID:16935330 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions
increases activity
decreases activity		 EXP Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]
Aminoglutethimide results in increased activity of CYP19A1 protein
Aminoglutethimide results in decreased activity of CYP19A1 protein		 CTD PMID:15242824 PMID:15968818 PMID:16935330 PMID:17910019 PMID:20087668 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G FSHB follicle stimulating hormone subunit beta decreases expression
multiple interactions		 EXP
ISO		 Aminoglutethimide results in decreased expression of FSHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]		 CTD PMID:9208491 PMID:22285649 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GATD3 glutamine amidotransferase class 1 domain containing 3 increases expression EXP Aminoglutethimide results in increased expression of GATD3 protein CTD PMID:26102013 NCBI chr21:44,133,683...44,145,711
Ensembl chr21:44,133,610...44,210,114 		JBrowse link
G GNS glucosamine (N-acetyl)-6-sulfatase decreases expression EXP Aminoglutethimide results in decreased expression of GNS protein CTD PMID:26102013 NCBI chr12:64,713,449...64,759,406
Ensembl chr12:64,713,445...64,759,431 		JBrowse link
G GPX1 glutathione peroxidase 1 increases expression EXP Aminoglutethimide results in increased expression of GPX1 protein CTD PMID:26102013 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSN gelsolin decreases expression EXP Aminoglutethimide results in decreased expression of GSN protein CTD PMID:26102013 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G H1-2 H1.2 linker histone, cluster member increases expression EXP Aminoglutethimide results in increased expression of H1-2 protein CTD PMID:26102013 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470 		JBrowse link
G H2AC12 H2A clustered histone 12 increases expression EXP Aminoglutethimide results in increased expression of H2AC12 protein CTD PMID:26102013 NCBI chr 6:27,147,106...27,147,562
Ensembl chr 6:27,147,106...27,147,562 		JBrowse link
G H2AZ1 H2A.Z variant histone 1 increases expression EXP Aminoglutethimide results in increased expression of H2AZ1 protein CTD PMID:26102013 NCBI chr 4:99,948,088...99,950,275
Ensembl chr 4:99,948,086...99,950,355 		JBrowse link
G H2BC12 H2B clustered histone 12 increases expression EXP Aminoglutethimide results in increased expression of H2BC12 protein CTD PMID:26102013 NCBI chr 6:27,138,293...27,146,858
Ensembl chr 6:27,137,298...27,146,855 		JBrowse link
G H3C13 H3 clustered histone 13 increases expression EXP Aminoglutethimide results in increased expression of H3C13 protein CTD PMID:26102013 NCBI chr 1:149,813,225...149,813,693
Ensembl chr 1:149,813,225...149,813,693 		JBrowse link
G H3C7 H3 clustered histone 7 increases expression EXP Aminoglutethimide results in increased expression of H3C7 protein CTD PMID:26102013 NCBI chr 6:26,250,142...26,250,635
Ensembl chr 6:26,250,142...26,250,635 		JBrowse link
G H4C8 H4 clustered histone 8 increases expression EXP Aminoglutethimide results in increased expression of H4C8 protein CTD PMID:26102013 NCBI chr 6:26,285,126...26,285,534
Ensembl chr 6:26,277,609...26,285,638 		JBrowse link
G HMGB2 high mobility group box 2 decreases expression EXP Aminoglutethimide results in decreased expression of HMGB2 protein CTD PMID:26102013 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 decreases expression EXP Aminoglutethimide results in decreased expression of HNRNPH1 protein CTD PMID:26102013 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 multiple interactions EXP [Colforsin co-treated with Aminoglutethimide] results in decreased expression of HSD17B1 mRNA CTD PMID:16935330 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 decreases expression EXP Aminoglutethimide results in decreased expression of HSD17B10 protein CTD PMID:26102013 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 multiple interactions
decreases expression		 EXP Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of HSD17B4 mRNA]
Aminoglutethimide results in decreased expression of HSD17B4 mRNA		 CTD PMID:16935330 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 decreases expression ISO Aminoglutethimide results in decreased expression of HSD17B7 mRNA CTD PMID:9231770 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP Aminoglutethimide results in increased expression of HSPA1A protein CTD PMID:26102013 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HYOU1 hypoxia up-regulated 1 increases expression EXP Aminoglutethimide results in increased expression of HYOU1 protein CTD PMID:26102013 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 decreases expression EXP Aminoglutethimide results in decreased expression of IMPDH2 protein CTD PMID:26102013 NCBI chr 3:49,024,325...49,029,398
Ensembl chr 3:49,024,325...49,029,447 		JBrowse link
G LHB luteinizing hormone subunit beta decreases expression
multiple interactions		 EXP
ISO		 Aminoglutethimide results in decreased expression of LHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]		 CTD PMID:9208491 PMID:22285649 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LMNA lamin A/C decreases expression EXP Aminoglutethimide results in decreased expression of LMNA protein CTD PMID:26102013 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,572...156,140,081 		JBrowse link
G LMNB2 lamin B2 decreases expression EXP Aminoglutethimide results in decreased expression of LMNB2 protein CTD PMID:26102013 NCBI chr19:2,428,166...2,456,959
Ensembl chr19:2,427,638...2,456,959 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 decreases expression EXP Aminoglutethimide results in decreased expression of MCM3 protein CTD PMID:26102013 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881 		JBrowse link
G MPO myeloperoxidase multiple interactions EXP [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide] which results in increased expression of MPO protein modified form; [Aminoglutethimide co-treated with Hydrogen Peroxide] results in increased oxidation of MPO protein; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide CTD PMID:20199096 PMID:26102013 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MYO18A myosin XVIIIA decreases expression EXP Aminoglutethimide results in decreased expression of MYO18A protein CTD PMID:26102013 NCBI chr17:29,071,122...29,180,398
Ensembl chr17:29,071,122...29,180,398 		JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 decreases expression EXP Aminoglutethimide results in decreased expression of NPM3 protein CTD PMID:26102013 NCBI chr10:101,781,325...101,783,446
Ensembl chr10:101,781,325...101,783,446 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity EXP Aminoglutethimide results in increased activity of NR1I2 protein CTD PMID:21068194 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NUP210 nucleoporin 210 decreases expression EXP Aminoglutethimide results in decreased expression of NUP210 protein CTD PMID:26102013 NCBI chr 3:13,316,235...13,420,322
Ensembl chr 3:13,316,235...13,420,322 		JBrowse link
G PGR progesterone receptor multiple interactions
decreases expression		 EXP [Aminoglutethimide co-treated with 17 alpha-Hydroxyprogesterone Caproate] results in decreased expression of PGR protein
Aminoglutethimide results in decreased expression of PGR protein		 CTD PMID:8565696 PMID:9208491 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PITPNB phosphatidylinositol transfer protein beta increases expression EXP Aminoglutethimide results in increased expression of PITPNB protein CTD PMID:26102013 NCBI chr22:27,851,669...27,919,256
Ensembl chr22:27,851,669...27,920,134 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha decreases expression EXP Aminoglutethimide results in decreased expression of PPP1CA protein CTD PMID:26102013 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PRDX3 peroxiredoxin 3 increases expression EXP Aminoglutethimide results in increased expression of PRDX3 protein CTD PMID:26102013 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812 		JBrowse link
G PSMB4 proteasome 20S subunit beta 4 decreases expression EXP Aminoglutethimide results in decreased expression of PSMB4 protein CTD PMID:26102013 NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937 		JBrowse link
G RTRAF RNA transcription, translation and transport factor decreases expression EXP Aminoglutethimide results in decreased expression of RTRAF protein CTD PMID:26102013 NCBI chr14:51,989,546...52,010,694
Ensembl chr14:51,989,514...52,010,694 		JBrowse link
G SPP1 secreted phosphoprotein 1 decreases expression ISO Aminoglutethimide results in decreased expression of SPP1 mRNA CTD PMID:23558518 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SSB small RNA binding exonuclease protection factor La decreases expression EXP Aminoglutethimide results in decreased expression of SSB protein CTD PMID:26102013 NCBI chr 2:169,798,871...169,812,064
Ensembl chr 2:169,791,933...169,812,064 		JBrowse link
G STAR steroidogenic acute regulatory protein decreases expression
increases expression		 EXP
ISO		 Aminoglutethimide results in decreased expression of STAR mRNA
Aminoglutethimide results in increased expression of STAR mRNA		 CTD PMID:10960482 PMID:16935330 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G TPT1 tumor protein, translationally-controlled 1 decreases expression EXP Aminoglutethimide results in decreased expression of TPT1 protein CTD PMID:26102013 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284 		JBrowse link
G UBC ubiquitin C increases expression EXP Aminoglutethimide results in increased expression of UBC protein CTD PMID:26102013 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K decreases expression EXP Aminoglutethimide results in decreased expression of UBE2K protein CTD PMID:26102013 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792 		JBrowse link
G WDR1 WD repeat domain 1 increases expression EXP Aminoglutethimide results in increased expression of WDR1 protein CTD PMID:26102013 NCBI chr 4:10,074,339...10,116,799
Ensembl chr 4:10,068,089...10,116,972 		JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta increases expression EXP Aminoglutethimide results in increased expression of YWHAQ protein CTD PMID:26102013 NCBI chr 2:9,583,967...9,630,997
Ensembl chr 2:9,583,967...9,630,997 		JBrowse link
anastrozole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYCS cytochrome c, somatic multiple interactions EXP [Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Olive Oil co-treated with anastrozole] affects the localization of CYCS protein CTD PMID:24161488 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases activity EXP Anastrozole results in decreased activity of CYP19A1 protein CTD PMID:15837728 PMID:16001952 PMID:16023338 PMID:16023854 PMID:16034487 More... NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G FSHB follicle stimulating hormone subunit beta increases expression ISO anastrozole results in increased expression of FSHB protein CTD PMID:10657858 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression EXP anastrozole results in decreased expression of GJA1 protein CTD PMID:29180066 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G LHB luteinizing hormone subunit beta increases expression ISO anastrozole results in increased expression of LHB protein CTD PMID:10657858 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions
decreases expression		 EXP [Tamoxifen co-treated with anastrozole] results in decreased expression of MKI67 protein
anastrozole results in decreased expression of MKI67 protein		 CTD PMID:15767642 PMID:16002280 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G PGR progesterone receptor decreases expression EXP anastrozole results in decreased expression of PGR protein CTD PMID:16002280 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G POR cytochrome p450 oxidoreductase decreases activity EXP Anastrozole results in decreased activity of POR protein CTD PMID:35206146 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP anastrozole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATF apoptosis antagonizing transcription factor decreases expression EXP beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr17:36,948,954...37,056,871
Ensembl chr17:36,948,925...37,056,871 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACIN1 apoptotic chromatin condensation inducer 1 decreases expression EXP beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr14:23,058,564...23,095,614
Ensembl chr14:23,058,564...23,095,614 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403 		JBrowse link
G ACTB actin beta decreases expression EXP beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G AEN apoptosis enhancing nuclease decreases expression EXP beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr15:88,604,683...88,632,281
Ensembl chr15:88,621,337...88,632,281 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 decreases expression EXP beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G AK4 adenylate kinase 4 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145 		JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr 6:24,494,969...24,537,207
Ensembl chr 6:24,494,867...24,537,207 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A decreases expression EXP beauvericin results in decreased expression of ALDOA mRNA CTD PMID:29203277 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ANAPC13 anaphase promoting complex subunit 13 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 3:134,477,704...134,486,023
Ensembl chr 3:134,477,706...134,486,716 		JBrowse link
G APRT adenine phosphoribosyltransferase decreases expression EXP beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937 		JBrowse link
G AR androgen receptor multiple interactions EXP beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha decreases expression EXP beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,719...81,871,378 		JBrowse link
G ARPP21 cAMP regulated phosphoprotein 21 increases expression EXP beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 3:35,638,853...35,794,486
Ensembl chr 3:35,638,945...35,794,496 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773 		JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of BAX mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA		 CTD PMID:29203277 PMID:32956828 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions		 EXP beauvericin results in increased expression of BCL2 mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA		 CTD PMID:29203277 PMID:32956828 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 increases expression EXP beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 increases expression EXP beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BTF3L4 basic transcription factor 3 like 4 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 1:52,056,295...52,090,716
Ensembl chr 1:52,056,199...52,090,716 		JBrowse link
G C10orf88B C10orf88B (pseudogene) multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of C10ORF88B protein CTD PMID:32407736 NCBI chr10:122,879,633...122,898,714
Ensembl chr10:122,879,851...122,898,024 		JBrowse link
G C11orf21 chromosome 11 open reading frame 21 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of C11ORF21 protein CTD PMID:32407736 NCBI chr11:2,295,628...2,303,140
Ensembl chr11:2,295,628...2,303,049 		JBrowse link
G C1QTNF3 C1q and TNF related 3 decreases expression EXP beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr 5:34,017,858...34,244,724
Ensembl chr 5:34,017,858...34,043,213 		JBrowse link
G C1QTNF6 C1q and TNF related 6 increases expression EXP beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr22:37,180,166...37,199,423
Ensembl chr22:37,180,166...37,199,385 		JBrowse link
G CAAP1 caspase activity and apoptosis inhibitor 1 decreases expression EXP beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 9:26,840,685...26,892,802
Ensembl chr 9:26,840,685...26,892,803 		JBrowse link
G CARD11 caspase recruitment domain family member 11 decreases expression EXP beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CASP10 caspase 10 increases expression EXP beauvericin results in increased expression of CASP10 mRNA CTD PMID:29203277 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 beauvericin results in increased activity of CASP3 protein
[zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA		 CTD PMID:25178661 PMID:32956828 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 increases activity ISO beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 increases expression EXP beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases expression EXP beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 decreases expression EXP beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr 8:22,604,757...22,621,514
Ensembl chr 8:22,604,757...22,620,964 		JBrowse link
G CCDC124 coiled-coil domain containing 124 decreases expression EXP beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr19:17,933,015...17,943,985
Ensembl chr19:17,933,015...17,943,991 		JBrowse link
G CCDC180 coiled-coil domain containing 180 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 9:97,307,337...97,378,751
Ensembl chr 9:97,307,304...97,378,751 		JBrowse link
G CCDC86 coiled-coil domain containing 86 decreases expression EXP beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr11:60,842,113...60,851,081
Ensembl chr11:60,842,113...60,851,081 		JBrowse link
G CCNG2 cyclin G2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389 		JBrowse link
G CD47 CD47 molecule multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862 		JBrowse link
G CD81 CD81 molecule multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G CDK2AP2 cyclin dependent kinase 2 associated protein 2 decreases expression EXP beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr11:67,506,497...67,508,162
Ensembl chr11:67,506,497...67,508,649 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CEP170P1 centrosomal protein 170 pseudogene 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CEP170P1 protein CTD PMID:32407736 NCBI chr 4:118,516,325...118,554,204
Ensembl chr 4:118,467,590...118,554,100
Ensembl chr 4:118,467,590...118,554,100 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator increases expression EXP beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression EXP beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr 7:56,101,573...56,106,476
Ensembl chr 7:56,094,567...56,106,479 		JBrowse link
G CIAPIN1 cytokine induced apoptosis inhibitor 1 decreases expression EXP beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr16:57,428,187...57,447,385
Ensembl chr16:57,428,187...57,447,420 		JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740 		JBrowse link
G COA6 cytochrome c oxidase assembly factor 6 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr 1:234,373,456...234,385,080
Ensembl chr 1:234,373,456...234,385,080 		JBrowse link
G CORO1C coronin 1C multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:108,645,109...108,731,518
Ensembl chr12:108,645,109...108,731,526 		JBrowse link
G COTL1 coactosin like F-actin binding protein 1 decreases expression EXP beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr16:84,565,596...84,618,078
Ensembl chr16:84,565,596...84,618,078 		JBrowse link
G CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 1:16,231,692...16,237,183
Ensembl chr 1:16,231,692...16,237,183 		JBrowse link
G CPNE1 copine 1 decreases expression EXP beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr20:35,626,044...35,664,900
Ensembl chr20:35,626,031...35,664,956 		JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 2:36,355,778...36,551,135
Ensembl chr 2:36,355,778...36,551,135 		JBrowse link
G CSDC2 cold shock domain containing C2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr22:41,561,010...41,576,666
Ensembl chr22:41,561,010...41,577,741 		JBrowse link
G CSK C-terminal Src kinase decreases expression EXP beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CTPS1 CTP synthase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565 		JBrowse link
G CTSD cathepsin D multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CXCL8 protein CTD PMID:32407736 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr19:15,508,525...15,552,317
Ensembl chr19:15,508,525...15,552,317 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709 		JBrowse link
G DDIAS DNA damage induced apoptosis suppressor decreases expression EXP beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr11:82,901,736...82,934,659
Ensembl chr11:82,899,975...82,958,277 		JBrowse link
G DDX47 DEAD-box helicase 47 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr12:12,813,346...12,829,981
Ensembl chr12:12,813,316...12,829,981 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr14:60,144,119...60,169,889
Ensembl chr14:60,144,119...60,169,856 		JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A decreases expression EXP beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463 		JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 increases expression EXP beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr12:49,866,896...49,903,900
Ensembl chr12:49,866,896...49,904,217 		JBrowse link
G FAM157A family with sequence similarity 157 member A multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of FAM157A protein CTD PMID:32407736 NCBI chr 3:198,153,206...198,222,513
Ensembl chr 3:198,180,755...198,190,365 		JBrowse link
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 7:139,340,472...139,346,328
Ensembl chr 7:139,339,457...139,346,328 		JBrowse link
G GAA alpha glucosidase multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
G GNA14 G protein subunit alpha 14 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 9:77,423,079...77,648,322
Ensembl chr 9:77,423,079...77,648,322 		JBrowse link
G GNAI3 G protein subunit alpha i3 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GNB1 G protein subunit beta 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292 		JBrowse link
G GOLGA1 golgin A1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 9:124,878,275...124,948,043
Ensembl chr 9:124,878,275...124,948,492 		JBrowse link
G GPNMB glycoprotein nmb multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GPR18 G protein-coupled receptor 18 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr13:99,254,739...99,258,379
Ensembl chr13:99,254,732...99,261,744 		JBrowse link
G H2BC11 H2B clustered histone 11 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 6:27,132,316...27,132,795
Ensembl chr 6:27,122,657...27,132,795 		JBrowse link
G HEXB hexosaminidase subunit beta multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HNRNPM heterogeneous nuclear ribonucleoprotein M multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr19:8,444,975...8,489,114
Ensembl chr19:8,444,767...8,489,114 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G IL32 interleukin 32 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of IL32 mRNA CTD PMID:31100301 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IMMT inner membrane mitochondrial protein multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 2:86,143,936...86,195,462
Ensembl chr 2:86,143,932...86,195,472 		JBrowse link
G INSIG1 insulin induced gene 1 increases expression EXP beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr15:74,100,318...74,141,826
Ensembl chr15:74,100,311...74,138,540 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G JSRP1 junctional sarcoplasmic reticulum protein 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of JSRP1 protein CTD PMID:32407736 NCBI chr19:2,252,252...2,256,417
Ensembl chr19:2,252,252...2,269,759 		JBrowse link
G KLF12 KLF transcription factor 12 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr13:73,686,089...74,306,045
Ensembl chr13:73,686,089...74,134,404 		JBrowse link
G KPNB1 karyopherin subunit beta 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr17:47,649,919...47,685,505
Ensembl chr17:47,649,476...47,685,505 		JBrowse link
G KRT16 keratin 16 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G KRT27 keratin 27 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr17:40,776,808...40,782,550
Ensembl chr17:40,776,808...40,782,550 		JBrowse link
G KRT5 keratin 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530 		JBrowse link
G KRT76 keratin 76 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr12:52,768,155...52,777,345
Ensembl chr12:52,768,155...52,777,345 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G LAT linker for activation of T cells decreases expression EXP beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr16:28,984,803...28,990,784
Ensembl chr16:28,984,826...28,990,784 		JBrowse link
G LGALS14 galectin 14 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of LGALS14 protein CTD PMID:32407736 NCBI chr19:39,704,481...39,709,444
Ensembl chr19:39,704,481...39,709,444 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation ISO beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation ISO beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MATN4 matrilin 4 decreases expression EXP beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr20:45,293,450...45,308,684
Ensembl chr20:45,293,445...45,308,529 		JBrowse link
G MAVS mitochondrial antiviral signaling protein increases expression EXP beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MED6 mediator complex subunit 6 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr14:70,583,221...70,600,655
Ensembl chr14:70,581,257...70,600,690 		JBrowse link
G MOAP1 modulator of apoptosis 1 increases expression EXP beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr14:93,182,199...93,184,897
Ensembl chr14:93,182,199...93,184,923 		JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA		 CTD PMID:29203277 PMID:31100301 NCBI chr17:81,703,367...81,707,517
Ensembl chr17:81,703,367...81,707,517 		JBrowse link
G MRPL4 mitochondrial ribosomal protein L4 decreases expression EXP beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr19:10,251,951...10,260,055
Ensembl chr19:10,251,901...10,260,055 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT-ATP8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:8,366...8,572
Ensembl chr MT:8,366...8,572 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of COX1 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MT-CO3 mitochondrially encoded cytochrome c oxidase III decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of COX3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990 		JBrowse link
G MT-CYB mitochondrially encoded cytochrome b decreases expression EXP beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887 		JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
increases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND2 mRNA
beauvericin results in increased expression of ND2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511 		JBrowse link
G MT-ND3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
increases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND3 mRNA
beauvericin results in increased expression of ND3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,059...10,404
Ensembl chr MT:10,059...10,404 		JBrowse link
G MT-ND4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137 		JBrowse link
G MT-ND4L mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression
increases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND4L mRNA
beauvericin results in increased expression of ND4L mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4L mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,470...10,766
Ensembl chr MT:10,470...10,766 		JBrowse link
G MT-ND5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
increases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND5 mRNA
beauvericin results in increased expression of ND5 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND5 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148 		JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of ND6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND6 mRNA		 CTD PMID:34015425 NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673 		JBrowse link
G MT-RNR2 mitochondrially encoded 16S rRNA increases expression
multiple interactions		 EXP beauvericin results in increased expression of RNR2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of RNR2 mRNA; [beauvericin co-treated with enniatins] affects the expression of RNR2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of RNR2 mRNA		 CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:1,671...3,229
Ensembl chr MT:1,671...3,229 		JBrowse link
G MTATP6P1 MT-ATP6 pseudogene 1 decreases expression EXP beauvericin results in decreased expression of MTATP6P1 mRNA CTD PMID:29203277 NCBI chr 1:633,696...634,376
Ensembl chr 1:633,696...634,376 		JBrowse link
G MTRF1L mitochondrial translation release factor 1 like multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 6:152,987,362...153,002,709
Ensembl chr 6:152,987,362...153,002,709 		JBrowse link
G MTRNR2L2 MT-RNR2 like 2 (pseudogene) increases expression EXP beauvericin results in increased expression of MTRNR2L2 mRNA CTD PMID:36016515 NCBI chr 5:80,650,420...80,651,030
Ensembl chr 5:80,650,000...80,650,086 		JBrowse link
G MTRNR2L8 MT-RNR2 like 8 (pseudogene) increases expression EXP beauvericin results in increased expression of MTRNR2L8 mRNA CTD PMID:36016515 NCBI chr11:10,507,887...10,509,176
Ensembl chr11:10,507,894...10,509,186 		JBrowse link
G MYO18A myosin XVIIIA increases expression EXP beauvericin results in increased expression of MYO18A mRNA CTD PMID:29203277 NCBI chr17:29,071,122...29,180,398
Ensembl chr17:29,071,122...29,180,398 		JBrowse link
G NARS1 asparaginyl-tRNA synthetase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:57,600,656...57,621,836
Ensembl chr18:57,600,656...57,622,213 		JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr11:78,435,968...78,574,864
Ensembl chr11:78,435,620...78,575,194 		JBrowse link
G NDRG1 N-myc downstream regulated 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NEXN-AS1 NEXN antisense RNA 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of NEXN-AS1 protein CTD PMID:32407736 NCBI chr 1:77,881,348...77,889,539
Ensembl chr 1:77,881,348...77,889,539 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 increases expression EXP beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 increases expression EXP beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOL3 nucleolar protein 3 increases expression EXP beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NUDT1 nudix hydrolase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,226...2,251,146 		JBrowse link
G OGA O-GlcNAcase increases expression EXP beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr10:101,784,450...101,818,444
Ensembl chr10:101,784,443...101,818,465 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase increases expression EXP beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 multiple interactions
increases expression		 EXP [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of OSGIN1 mRNA
beauvericin results in increased expression of OSGIN1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332 		JBrowse link
G OSTC oligosaccharyltransferase complex non-catalytic subunit multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 4:108,650,599...108,667,820
Ensembl chr 4:108,650,585...108,667,820 		JBrowse link
G PARVG parvin gamma multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr22:44,172,951...44,208,469
Ensembl chr22:44,172,956...44,219,533 		JBrowse link
G PAWR pro-apoptotic WT1 regulator decreases expression EXP beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964 		JBrowse link
G PDCD11 programmed cell death 11 decreases expression EXP beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr10:103,396,626...103,446,294
Ensembl chr10:103,396,626...103,446,294 		JBrowse link
G PDCD2 programmed cell death 2 decreases expression EXP beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr 6:170,575,295...170,584,637
Ensembl chr 6:170,575,295...170,584,692 		JBrowse link
G PDCD2L programmed cell death 2 like increases expression EXP beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr19:34,404,399...34,426,168
Ensembl chr19:34,404,399...34,426,168 		JBrowse link
G PDCD4 programmed cell death 4 decreases expression EXP beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006 		JBrowse link
G PDCD5 programmed cell death 5 increases expression EXP beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr19:32,581,190...32,587,453
Ensembl chr19:32,581,190...32,587,453 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein increases expression EXP beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 decreases expression EXP beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PFN1 profilin 1 decreases expression
multiple interactions		 EXP beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein		 CTD PMID:29203277 PMID:32407736 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PHGDH phosphoglycerate dehydrogenase multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218 		JBrowse link
G PHKA2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:18,892,298...18,984,114
Ensembl chr  X:18,892,298...18,984,114 		JBrowse link
G PIDD1 p53-induced death domain protein 1 decreases expression EXP beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr11:799,184...809,501
Ensembl chr11:799,179...809,753 		JBrowse link
G PLK1 polo like kinase 1 decreases expression EXP beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLS3 plastin 3 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:115,561,174...115,650,861
Ensembl chr  X:115,561,174...115,650,861 		JBrowse link
G POTEJ POTE ankyrin domain family member J multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of POTEJ protein CTD PMID:32407736 NCBI chr 2:130,611,078...130,658,037
Ensembl chr 2:130,611,440...130,658,037 		JBrowse link
G PPA1 inorganic pyrophosphatase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr10:70,202,835...70,233,429
Ensembl chr10:70,202,835...70,233,911 		JBrowse link
G PPAN peter pan homolog decreases expression EXP beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr19:10,106,223...10,112,012
Ensembl chr19:10,106,362...10,112,012 		JBrowse link
G PPIAL4A peptidylprolyl isomerase A like 4A multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of PPIAL4A protein CTD PMID:32407736 NCBI chr 1:120,889,771...120,890,530
Ensembl chr 1:120,889,771...120,890,530 		JBrowse link
G PPIB peptidylprolyl isomerase B decreases expression EXP beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G PPP1R14B protein phosphatase 1 regulatory inhibitor subunit 14B decreases expression EXP beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr11:64,244,479...64,246,943
Ensembl chr11:64,244,479...64,246,943 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G PRKCA protein kinase C alpha multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PSMA5 proteasome 20S subunit alpha 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448 		JBrowse link
G PSME4 proteasome activator subunit 4 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr 2:53,864,069...53,970,993
Ensembl chr 2:53,864,069...53,970,993 		JBrowse link
G PTGES3 prostaglandin E synthase 3 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G RAB11FIP5 RAB11 family interacting protein 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 2:73,073,382...73,112,948
Ensembl chr 2:73,073,382...73,156,721 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175 		JBrowse link
G RAC3 Rac family small GTPase 3 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr17:82,031,678...82,034,204
Ensembl chr17:82,031,678...82,034,204 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RELT RELT TNF receptor decreases expression EXP beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr11:73,376,399...73,397,474
Ensembl chr11:73,376,399...73,397,474 		JBrowse link
G RP2 RP2 activator of ARL3 GTPase multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:46,837,043...46,882,358
Ensembl chr  X:46,837,043...46,882,358 		JBrowse link
G RPL37A ribosomal protein L37a multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180 		JBrowse link
G RPL5 ribosomal protein L5 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr 1:92,831,986...92,841,924
Ensembl chr 1:92,832,013...92,841,924 		JBrowse link
G RPL8 ribosomal protein L8 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 8:144,789,769...144,792,390
Ensembl chr 8:144,789,765...144,792,587 		JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SCML2 Scm polycomb group protein like 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:18,239,313...18,355,118
Ensembl chr  X:18,239,313...18,354,688 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr16:22,162,506...22,191,751
Ensembl chr16:22,162,492...22,192,208 		JBrowse link
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression EXP beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 3:10,300,931...10,321,112
Ensembl chr 3:10,293,131...10,321,112 		JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor decreases expression EXP beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr14:104,753,147...104,759,654
Ensembl chr14:104,753,147...104,768,494 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SNRPD2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr19:45,687,454...45,692,316
Ensembl chr19:45,687,460...45,692,569 		JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr22:24,555,650...24,574,971
Ensembl chr22:24,555,958...24,582,052 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase decreases activity ISO beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRM spermidine synthase decreases expression EXP beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020 		JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494 		JBrowse link
G SRXN1 sulfiredoxin 1 multiple interactions
decreases expression		 EXP [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of SRXN1 mRNA
beauvericin results in decreased expression of SRXN1 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 7:141,738,321...141,750,488
Ensembl chr 7:141,738,334...141,787,922 		JBrowse link
G TBC1D2B TBC1 domain family member 2B multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr15:77,994,985...78,077,711
Ensembl chr15:77,984,036...78,077,724 		JBrowse link
G TCN2 transcobalamin 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271 		JBrowse link
G TCP11L1 t-complex 11 like 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr11:33,039,572...33,073,563
Ensembl chr11:33,039,417...33,105,943 		JBrowse link
G TCP11L2 t-complex 11 like 2 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr12:106,297,935...106,347,003
Ensembl chr12:106,301,929...106,347,538 		JBrowse link
G THYN1 thymocyte nuclear protein 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr11:134,248,282...134,253,352
Ensembl chr11:134,248,279...134,253,370 		JBrowse link
G TIMM9 translocase of inner mitochondrial membrane 9 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr14:58,408,494...58,427,531
Ensembl chr14:58,408,495...58,427,531 		JBrowse link
G TK1 thymidine kinase 1 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TMEM263 transmembrane protein 263 multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr12:106,955,907...106,974,035
Ensembl chr12:106,955,719...106,978,778 		JBrowse link
G TNFSF10 TNF superfamily member 10 decreases expression EXP beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TOMM22 translocase of outer mitochondrial membrane 22 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr22:38,681,957...38,685,421
Ensembl chr22:38,681,957...38,685,421 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849 		JBrowse link
G TUBA1B tubulin alpha 1b multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB tubulin beta class I multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538 		JBrowse link
G TUBB3 tubulin beta 3 class III multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G TUBB4A tubulin beta 4A class IVa multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr19:6,494,319...6,502,848
Ensembl chr19:6,494,319...6,502,848 		JBrowse link
G TUBB4B tubulin beta 4B class IVb multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707 		JBrowse link
G TXNIP thioredoxin interacting protein increases expression
multiple interactions
decreases expression		 EXP beauvericin results in increased expression of TXNIP mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of TXNIP mRNA
beauvericin results in decreased expression of TXNIP mRNA		 CTD PMID:29203277 PMID:34015425 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP2 uncoupling protein 2 multiple interactions
decreases expression		 EXP [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA
beauvericin results in decreased expression of UCP2 mRNA		 CTD PMID:31100301 PMID:34015425 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843 		JBrowse link
G UCP3 uncoupling protein 3 multiple interactions EXP [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085 		JBrowse link
G YBX1 Y-box binding protein 1 decreases expression EXP beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805 		JBrowse link
G YBX3 Y-box binding protein 3 decreases expression EXP beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr12:10,699,089...10,723,323
Ensembl chr12:10,699,089...10,723,323 		JBrowse link
G YKT6 YKT6 v-SNARE homolog multiple interactions EXP [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr 7:44,200,978...44,214,294
Ensembl chr 7:44,200,959...44,214,294 		JBrowse link
carbon monoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 increases activity ISO Carbon Monoxide results in increased activity of ABCC2 protein CTD PMID:13678533 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein
[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased expression of PECAM1 protein; Carbon Monoxide results in increased expression of ADIPOQ protein		 CTD PMID:19356108 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin increases expression ISO Carbon Monoxide results in increased expression of ADM mRNA; Carbon Monoxide results in increased expression of ADM protein CTD PMID:10666155 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AGT angiotensinogen decreases response to substance ISO AGT protein results in decreased susceptibility to Carbon Monoxide CTD PMID:18174886 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein]; Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of AKT1 protein]
Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD PMID:17179207 PMID:18037988 PMID:18215737 PMID:18845810 PMID:19356108 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions
increases activity		 ISO Carbon Monoxide inhibits the reaction [[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein]
Carbon Monoxide results in increased activity of ALAD protein		 CTD PMID:1032310 PMID:6740708 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G AREG amphiregulin multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G BACH1 BTB domain and CNC homolog 1 decreases phosphorylation ISO Carbon Monoxide results in decreased phosphorylation of BACH1 protein CTD PMID:18845810 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein] CTD PMID:18037988 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BCL2A1 BCL2 related protein A1 multiple interactions EXP BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
decreases expression		 ISO Carbon Monoxide results in decreased expression of and results in decreased secretion of BDNF protein
Carbon Monoxide results in decreased expression of BDNF mRNA		 CTD PMID:27113706 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions EXP BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity		 ISO
EXP		 [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; Carbon Monoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein; Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP3 mRNA]; tin protoporphyrin IX inhibits the reaction [Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]]
Carbon Monoxide results in increased expression of CASP3 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Carbon Monoxide results in increased activity of CASP3 protein		 CTD PMID:17173083 PMID:19356108 PMID:19520142 PMID:25562542 PMID:31268311 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 increases activity ISO Carbon Monoxide results in increased activity of CASP7 protein CTD PMID:25562542 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 increases activity
multiple interactions		 ISO
EXP		 Carbon Monoxide results in increased activity of CASP8 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA		 CTD PMID:25562542 PMID:31268311 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,