EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	*EC 2.5. (non-methyl-alkyl or aryl transferase) inhibitor**	go back to main search page
Accession:	CHEBI:76834	browse the term
Definition:	An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*).
Synonyms:	related_synonym:	EC 2.5.* inhibitor; EC 2.5.* inhibitors; non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors

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Rat (3457 ) Mouse (3474 ) Human (3393 ) Chinchilla (0 ) Bonobo (0 ) Dog (0 ) Squirrel (0 ) Pig (41 ) Green Monkey (0) Naked Mole-rat (0 ) All
Genes (3457)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

decreases phosphorylation

ISO

ABT-100 results in decreased phosphorylation of AKT1 protein

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

cyclin dependent kinase 2

decreases activity

ISO

ABT-100 results in decreased activity of CDK2 protein

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase inhibitor 1B

decreases phosphorylation
increases expression

ISO

ABT-100 results in decreased phosphorylation of CDKN1B protein
ABT-100 results in increased expression of CDKN1B protein

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

HRas proto-oncogene, GTPase

decreases farnesylation

ISO

ABT-100 results in decreased farnesylation of HRAS protein

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

phosphoinositide-3-kinase regulatory subunit 1

decreases phosphorylation

ISO

ABT-100 results in decreased phosphorylation of PIK3R1 protein

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

alendronic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aggrecan

multiple interactions
increases expression

ISO

Alendronate inhibits the reaction [TNF protein results in increased expression of ACAN mRNA]
Alendronate results in increased expression of ACAN mRNA

NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779

G

acetylcholinesterase

multiple interactions

ISO

Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

acid phosphatase 5, tartrate resistant

multiple interactions

EXP

Alendronate inhibits the reaction [Dexamethasone results in increased activity of ACP5 protein]; Alendronate inhibits the reaction [modafinil results in increased expression of ACP5 mRNA]

PMID:27387537 PMID:29649498

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929

G

adenylate cyclase activating polypeptide 1

affects expression

EXP

Alendronate affects the expression of ADCYAP1 mRNA

NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383

G

alkaline phosphatase, biomineralization associated

multiple interactions

EXP

Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]]

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

amyloid beta precursor protein

multiple interactions

ISO

Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

ATPase Na+/K+ transporting subunit alpha 1

affects expression

EXP

Alendronate affects the expression of ATP1A1 mRNA

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425

G

beta-secretase 1

multiple interactions

ISO

Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]

NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918

G

BCL2 associated X, apoptosis regulator

increases expression

ISO

Alendronate results in increased expression of BAX protein

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL2, apoptosis regulator

decreases expression

ISO

Alendronate results in decreased expression of BCL2 protein

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

bone gamma-carboxyglutamate protein

multiple interactions

EXP

[Nebivolol co-treated with Alendronate] inhibits the reaction [Methylprednisolone results in decreased secretion of BGLAP protein]

NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318

G

caspase 3

increases cleavage

ISO

Alendronate results in increased cleavage of CASP3 protein

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 9

multiple interactions

ISO

TNFSF11 inhibits the reaction [Alendronate results in increased expression of CASP9 protein]

Ensembl chr 5:159,391,188...159,409,648

G

catalase

multiple interactions

EXP
ISO

Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]]
Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]

PMID:30291735 PMID:30481507

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cyclin D1

decreases expression

ISO

Alendronate results in decreased expression of CCND1 protein

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin D3

decreases expression

ISO

Alendronate results in decreased expression of CCND3 protein

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033

G

CD3 gamma subunit of T-cell receptor complex

affects expression

EXP

Alendronate affects the expression of CD3G mRNA

NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918

G

cadherin 2

affects expression

EXP

Alendronate affects the expression of CDH2 mRNA

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 6

affects expression

EXP

Alendronate affects the expression of CDH6 mRNA

NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287

G

CDK5 regulatory subunit associated protein 3

affects expression

EXP

Alendronate affects the expression of CDK5RAP3 mRNA

NCBI chr10:82,390,845...82,402,814
Ensembl chr10:82,390,845...82,400,001

G

collagen type XI alpha 1 chain

affects expression

EXP

Alendronate affects the expression of COL11A1 mRNA

NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264

G

collagen type II alpha 1 chain

increases expression
multiple interactions

ISO

Alendronate results in increased expression of COL2A1 mRNA
Alendronate inhibits the reaction [TNF protein results in increased expression of COL2A1 mRNA]

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

collagen type V alpha 1 chain

affects expression

EXP

Alendronate affects the expression of COL5A1 mRNA

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

affects expression

EXP

Alendronate affects the expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type IX alpha 2 chain

multiple interactions
increases expression

ISO

Alendronate inhibits the reaction [TNF protein results in increased expression of COL9A2 mRNA]
Alendronate results in increased expression of COL9A2 mRNA

NCBI chr 5:139,892,798...139,910,131
Ensembl chr 5:139,892,798...139,909,855

G

carboxypeptidase E

affects expression

EXP

Alendronate affects the expression of CPE mRNA

NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524

G

crystallin, beta B2

affects expression

EXP

Alendronate affects the expression of CRYBB2 mRNA

NCBI chr12:49,230,192...49,240,116
Ensembl chr12:49,230,192...49,240,116

G

cytochrome P450, family 2, subfamily a, polypeptide 1

affects expression

EXP

Alendronate affects the expression of CYP2A1 mRNA

NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730

G

dual specificity phosphatase 6

affects expression

EXP

Alendronate affects the expression of DUSP6 mRNA

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

egl-9 family hypoxia-inducible factor 3

affects expression

EXP

Alendronate affects the expression of EGLN3 mRNA

NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015

G

farnesyl diphosphate synthase

decreases activity

ISO

Alendronate results in decreased activity of FDPS protein

NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136

G

fibroblast growth factor 9

affects expression

EXP

Alendronate affects the expression of FGF9 mRNA

NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926

G

FKBP prolyl isomerase 3

affects expression

EXP

Alendronate affects the expression of FKBP3 mRNA

NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447

G

gamma-aminobutyric acid type A receptor subunit gamma 1

affects expression

EXP

Alendronate affects the expression of GABRG1 mRNA

NCBI chr14:37,750,292...37,821,651
Ensembl chr14:37,750,292...37,989,945

G

growth hormone releasing hormone

affects expression

EXP

Alendronate affects the expression of GHRH mRNA

NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:166,412,764...166,431,880

G

growth hormone releasing hormone receptor

affects expression

EXP

Alendronate affects the expression of GHRHR mRNA

NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:85,830,486...85,863,127

G

G protein subunit beta 1

affects expression

EXP

Alendronate affects the expression of GNB1 mRNA

NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488

G

histidine ammonia lyase

affects expression

EXP

Alendronate affects the expression of HAL mRNA

NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744

G

high mobility group box 1

affects expression

EXP

Alendronate affects the expression of HMGB1 mRNA

NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327

G

homeobox A1

affects expression

EXP

Alendronate affects the expression of HOXA1 mRNA

NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:82,586,505...82,589,209

G

HRas proto-oncogene, GTPase

decreases prenylation

ISO

Alendronate results in decreased prenylation of HRAS protein

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

5-hydroxytryptamine receptor 5A

affects expression

EXP

Alendronate affects the expression of HTR5A mRNA

NCBI chr 4:8,178,802...8,188,485
Ensembl chr 4:8,178,802...8,200,482

G

isocitrate dehydrogenase (NADP(+)) 2

affects expression

EXP

Alendronate affects the expression of IDH2 mRNA

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

interleukin 18

multiple interactions

ISO

[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 1 beta

increases expression
multiple interactions

ISO
EXP

Alendronate results in increased expression of IL1B protein
Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]
[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Alendronate promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Clodronic Acid inhibits the reaction [Alendronate results in increased expression of IL1B protein]; Farnesol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geranylgeraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; Menthol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]

PMID:17375077 PMID:20304105 PMID:20804833 PMID:21430599 PMID:30481507

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor antagonist

multiple interactions

EXP

Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]

NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732

G

interleukin 6

multiple interactions

ISO

Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

potassium voltage-gated channel subfamily H member 5

affects expression

EXP

Alendronate affects the expression of KCNH5 mRNA

NCBI chr 6:99,350,947...99,643,856
Ensembl chr 6:99,360,302...99,643,856

G

lysyl oxidase

affects expression

EXP

Alendronate affects the expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

mitogen activated protein kinase 1

increases phosphorylation
decreases phosphorylation

ISO

Alendronate results in increased phosphorylation of MAPK1 protein
Alendronate results in decreased phosphorylation of MAPK1 protein

PMID:33522294 PMID:39137827

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 14

affects expression

EXP

Alendronate affects the expression of MAPK14 mRNA

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

increases phosphorylation

ISO

Alendronate results in increased phosphorylation of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mast cell protease 1

affects expression

EXP

Alendronate affects the expression of MCPT1 mRNA

NCBI chr15:33,841,606...33,844,174
Ensembl chr15:33,841,606...33,844,174

G

mast cell protease 4

affects expression

EXP

Alendronate affects the expression of MCPT4 mRNA

NCBI chr15:33,471,491...33,474,112
Ensembl chr15:33,471,491...33,474,110

G

matrix metallopeptidase 2

decreases expression
affects expression
decreases secretion

ISO
EXP

Alendronate results in decreased expression of MMP2 mRNA
Alendronate affects the expression of MMP2 mRNA
Alendronate results in decreased secretion of MMP2 protein

PMID:15049011 PMID:16079270

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

mucin 1, cell surface associated

affects expression

EXP

Alendronate affects the expression of MUC1 mRNA

NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491

G

myosin light chain 9

affects expression

EXP

Alendronate affects the expression of MYL9 mRNA

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410

G

nectin cell adhesion molecule 1

affects expression

EXP

Alendronate affects the expression of NECTIN1 mRNA

NCBI chr 8:52,998,662...53,061,745
Ensembl chr 8:52,998,662...53,086,664

G

nitric oxide synthase 2

multiple interactions

EXP

Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

olfactory receptor family 10 subfamily AL member 6

affects expression

EXP

Alendronate affects the expression of OR10AL6 mRNA

NCBI chr20:743,522...744,487
Ensembl chr20:743,522...816,076

G

poly (ADP-ribose) polymerase 1

increases cleavage

ISO

Alendronate results in increased cleavage of PARP1 protein

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

procollagen C-endopeptidase enhancer

affects expression

EXP

Alendronate affects the expression of PCOLCE mRNA

NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287

G

platelet and endothelial cell adhesion molecule 1

decreases expression

ISO

Alendronate results in decreased expression of PECAM1 mRNA

NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839

G

peroxisomal biogenesis factor 5

affects expression

EXP

Alendronate affects the expression of PEX5 mRNA

NCBI chr 4:158,956,973...158,983,581
Ensembl chr 4:158,956,974...158,982,733

G

PH domain and leucine rich repeat protein phosphatase 1

affects expression

EXP

Alendronate affects the expression of PHLPP mRNA

NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619

G

protein inhibitor of activated STAT, 3

affects expression

EXP

Alendronate affects the expression of PIAS3 mRNA

NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:186,921,428...186,936,714

G

polymeric immunoglobulin receptor

affects expression

EXP

Alendronate affects the expression of PIGR mRNA

NCBI chr13:44,851,001...44,879,143
Ensembl chr13:44,851,182...44,879,141

G

phospholipid phosphatase 1

affects expression

EXP

Alendronate affects the expression of PLPP1 mRNA

NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676

G

plasmalemma vesicle associated protein

decreases expression

ISO

Alendronate results in decreased expression of PLVAP mRNA

NCBI chr16:18,218,966...18,231,279
Ensembl chr16:18,218,967...18,231,454

G

paraoxonase 1

decreases activity
multiple interactions

EXP

Alendronate results in decreased activity of PON1 protein
[Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone; [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon; [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924

G

prosaposin

affects expression

EXP

Alendronate affects the expression of PSAP mRNA

NCBI chr20:28,756,951...28,783,422
Ensembl chr20:28,757,181...28,783,421

G

proteasome activator subunit 1

affects expression

EXP

Alendronate affects the expression of PSME1 mRNA

NCBI chr15:33,038,962...33,041,849
Ensembl chr15:33,038,597...33,041,848

G

prostaglandin F2 receptor inhibitor

affects expression

EXP

Alendronate affects the expression of PTGFRN mRNA

NCBI chr 2:191,158,166...191,233,432
Ensembl chr 2:191,158,166...191,234,115

G

prostaglandin-endoperoxide synthase 2

multiple interactions

EXP

Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RAP1A, member of RAS oncogene family

decreases prenylation

ISO

Alendronate results in decreased prenylation of RAP1A protein

NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808

G

retinoic acid receptor, alpha

affects expression

EXP

Alendronate affects the expression of RARA mRNA

NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160

G

RUNX family transcription factor 2

multiple interactions

EXP

Alendronate promotes the reaction [modafinil results in increased expression of RUNX2 mRNA]

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027

G

sodium voltage-gated channel alpha subunit 4

affects expression

EXP

Alendronate affects the expression of SCN4A mRNA

NCBI chr10:91,745,459...91,796,452
Ensembl chr10:91,746,715...91,796,324

G

serpin family E member 2

affects expression

EXP

Alendronate affects the expression of SERPINE2 mRNA

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202

G

serpin family H member 1

affects expression

EXP

Alendronate affects the expression of SERPINH1 mRNA

NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976

G

solute carrier family 18 member A2

affects expression

EXP

Alendronate affects the expression of SLC18A2 mRNA

NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231

G

solute carrier family 19 member 1

affects expression

EXP

Alendronate affects the expression of SLC19A1 mRNA

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488

G

solute carrier family 6 member 4

affects expression

EXP

Alendronate affects the expression of SLC6A4 mRNA

NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056

G

slit guidance ligand 1

affects expression

EXP

Alendronate affects the expression of SLIT1 mRNA

NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476

G

stannin

affects expression

EXP

Alendronate affects the expression of SNN mRNA

NCBI chr10:5,079,885...5,088,565
Ensembl chr 1:82,440,586...82,441,390
Ensembl chr10:82,440,586...82,441,390

G

SRY-box transcription factor 9

increases expression
multiple interactions

ISO

Alendronate results in increased expression of SOX9 mRNA; Alendronate results in increased expression of SOX9 protein
Alendronate inhibits the reaction [TNF protein results in increased expression of SOX9 mRNA]; Alendronate inhibits the reaction [TNF protein results in increased expression of SOX9 protein]; SP1 protein affects the reaction [Alendronate results in increased expression of SOX9 mRNA]; SP1 protein affects the reaction [Alendronate results in increased expression of SOX9 protein]

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

Sp1 transcription factor

multiple interactions
increases expression

ISO

SP1 protein affects the reaction [Alendronate results in increased expression of SOX9 mRNA]; SP1 protein affects the reaction [Alendronate results in increased expression of SOX9 protein]; U 0126 inhibits the reaction [Alendronate results in increased expression of SP1 mRNA]; U 0126 inhibits the reaction [Alendronate results in increased expression of SP1 protein]
Alendronate results in increased expression of SP1 mRNA; Alendronate results in increased expression of SP1 protein

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

secreted protein acidic and cysteine rich

affects expression

EXP

Alendronate affects the expression of SPARC mRNA

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268

G

serine/threonine kinase 4

increases cleavage

ISO

Alendronate results in increased cleavage of STK4 protein

NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:173,165,083...173,247,134

G

sulfotransferase family 5A, member 1

affects expression

EXP

Alendronate affects the expression of SULT5A1 mRNA

NCBI chr19:68,097,808...68,115,426
Ensembl chr19:68,097,808...68,112,656

G

transforming growth factor, beta 1

multiple interactions

EXP

[Alendronate co-treated with zoledronic acid] results in increased expression of TGFB1 protein

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

TIMP metallopeptidase inhibitor 1

affects expression

EXP

Alendronate affects the expression of TIMP1 mRNA

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

tumor necrosis factor

multiple interactions

ISO

[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]
Alendronate inhibits the reaction [TNF protein results in increased expression of ACAN mRNA]; Alendronate inhibits the reaction [TNF protein results in increased expression of COL2A1 mRNA]; Alendronate inhibits the reaction [TNF protein results in increased expression of COL9A2 mRNA]; Alendronate inhibits the reaction [TNF protein results in increased expression of SOX9 mRNA]; Alendronate inhibits the reaction [TNF protein results in increased expression of SOX9 protein]

PMID:21430599 PMID:30481507 PMID:33522294

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 11B

multiple interactions

EXP

Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF superfamily member 11

multiple interactions

ISO
EXP

TNFSF11 inhibits the reaction [Alendronate results in increased expression of CASP9 protein]
Alendronate inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 mRNA]; Alendronate inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 protein]; Alendronate inhibits the reaction [modafinil results in increased expression of TNFSF11 mRNA]

PMID:19405951 PMID:27387537 PMID:29649498

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

troponin I3, cardiac type

affects expression

EXP

Alendronate affects the expression of TNNI3 mRNA

NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253

G

vitamin D receptor

affects response to substance
multiple interactions

ISO

VDR gene polymorphism affects the susceptibility to Alendronate
VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]; VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Raloxifene Hydrochloride]

PMID:12608943 PMID:15739035

NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757

G

von Willebrand factor

decreases expression

ISO

Alendronate results in decreased expression of VWF mRNA

NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

colony stimulating factor 2

multiple interactions

ISO

andrastin A results in increased expression of and results in increased secretion of CSF2 protein

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

transforming growth factor, beta 1

multiple interactions

ISO

andrastin A results in increased expression of and results in increased secretion of TGFB1 protein

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

tumor necrosis factor

multiple interactions

ISO

andrastin A results in increased expression of and results in increased secretion of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nuclear factor kappa B subunit 1

decreases activity

ISO

B 581 results in decreased activity of NFKB1 protein

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

decreases phosphorylation

ISO

B 581 results in decreased phosphorylation of NFKBIA protein

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

RELA proto-oncogene, NF-kB subunit

decreases activity

ISO

B 581 results in decreased activity of RELA protein

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

bongkrekic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

increases expression

ISO

Bongkrekic Acid results in increased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169

G

activating transcription factor 4

multiple interactions

ISO

Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein]

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

DNA-damage inducible transcript 3

multiple interactions

ISO

Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of DDIT3 protein]

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

intercellular adhesion molecule 1

multiple interactions

ISO

Bongkrekic Acid inhibits the reaction [N-caproylsphingosine results in increased expression of ICAM1 mRNA]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

interleukin 24

decreases activity

ISO

Bongkrekic Acid results in decreased activity of IL24 protein

NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760

G

microsomal glutathione S-transferase 1

multiple interactions

EXP

Bongkrekic Acid inhibits the reaction [[Diamide co-treated with Glutathione] results in increased activity of MGST1 protein]

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

purinergic receptor P2X 1

increases activity

ISO

Bongkrekic Acid results in increased activity of P2RX1 protein

NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164

G

peptidyl arginine deiminase 4

increases activity

ISO

Bongkrekic Acid results in increased activity of PADI4 protein

NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:158,324,417...158,360,422

G

peroxisome proliferator-activated receptor gamma

increases activity

ISO

Bongkrekic Acid analog results in increased activity of PPARG protein; Bongkrekic Acid results in increased activity of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

solute carrier family 25 member 4

multiple interactions

EXP

Bongkrekic Acid inhibits the reaction [oxophenylarsine binds to SLC25A4 protein]

NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700

G

solute carrier family 25 member 5

decreases activity

ISO

Bongkrekic Acid results in decreased activity of SLC25A5 protein

NCBI chr X:120,897,616...120,900,683
Ensembl chr X:120,897,563...120,900,688

cis-caffeic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

ISO

caffeic acid results in increased phosphorylation of and results in decreased activity of ACACA protein

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetylcholinesterase

multiple interactions
decreases activity

EXP

caffeic acid inhibits the reaction [Caffeine results in decreased activity of ACHE protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of ACHE protein]

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

ATP citrate lyase

multiple interactions

ISO

[Metformin co-treated with caffeic acid] results in decreased expression of ACLY protein

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

arachidonate 15-lipoxygenase

multiple interactions
decreases activity

ISO

[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]; [caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; caffeic acid inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of ALOX15 protein]

PMID:10904086 PMID:11406566 PMID:15574791

NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723

G

arachidonate 5-lipoxygenase

multiple interactions

EXP
ISO

caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein]; caffeic acid inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein]
caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein]

PMID:18482095 PMID:18951527 PMID:27368151

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

amyloid beta precursor protein

multiple interactions

ISO

caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein modified form]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

arginase 1

decreases activity

ISO

caffeic acid results in decreased activity of ARG1 protein

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

ATPase H+ transporting V0 subunit D2

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA]

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245

G

caspase 3

multiple interactions

ISO
EXP

[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of CASP3 protein]

PMID:15574791 PMID:29968957

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

catalase

multiple interactions
increases activity

EXP
ISO

caffeic acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Nickel results in decreased activity of CAT protein]
caffeic acid results in increased activity of CAT protein
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]

PMID:18405891 PMID:21640567 PMID:22036979 PMID:27378625

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 2

multiple interactions

ISO

[Resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL2 mRNA; caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]

PMID:16806235 PMID:31306686

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 3

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL3 mRNA

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 4

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL4 mRNA

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine receptor 1

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR1 mRNA

NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374

G

C-C motif chemokine receptor 2

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

C-C motif chemokine receptor 4

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR4 mRNA

NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642

G

Cd4 molecule

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD4 mRNA

NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461

G

Cd68 molecule

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

cell division cycle 20

multiple interactions

ISO

[Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799

G

cyclin dependent kinase 2

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

choline O-acetyltransferase

multiple interactions

ISO

caffeic acid inhibits the reaction [aluminum chloride results in decreased expression of CHAT protein]

NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416

G

catechol-O-methyltransferase

increases methylation

ISO

COMT protein results in increased methylation of caffeic acid

NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533

G

corticotropin releasing hormone

multiple interactions

EXP

caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA]

NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386

G

cardiotrophin 1

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA]

NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395

G

cathepsin B

multiple interactions

EXP

caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cathepsin D

multiple interactions

EXP

caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

C-X-C motif chemokine ligand 2

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

EXP

caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

death-associated protein

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]

NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:83,910,060...83,962,673

G

DnaJ heat shock protein family (Hsp40) member B11

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA]

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800

G

dihydropyrimidinase-like 4

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]

NCBI chr 1:203,312,646...203,328,523
Ensembl chr 1:203,311,694...203,328,523

G

endothelin 1

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

early growth response 1

multiple interactions

ISO

caffeic acid affects the reaction [Acetaminophen results in increased expression of and affects the localization of EGR1 protein]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of EGR1 mRNA]

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

engulfment and cell motility 2

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]

NCBI chr 3:174,442,965...174,716,723
Ensembl chr 3:174,442,965...174,480,459

G

Ets2 repressor factor

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA]

NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213

G

coagulation factor III, tissue factor

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased expression of F3 protein]

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

fatty acid synthase

decreases expression
multiple interactions

ISO

caffeic acid results in decreased expression of FASN mRNA
[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein

PMID:21870829 PMID:28576465

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

fibronectin leucine rich transmembrane protein 2

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]

NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004

G

Fms related receptor tyrosine kinase 4

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]

NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645

G

glucose-6-phosphate dehydrogenase

decreases activity

ISO

caffeic acid results in decreased activity of G6PD protein

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A mRNA]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A protein]

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

galactosidase, beta 1

multiple interactions

EXP

caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein]

NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326

G

glutaminase

increases expression

ISO

caffeic acid results in increased expression of GLS protein

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861

G

glutamic-oxaloacetic transaminase 1

multiple interactions

EXP

caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein]

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glutamic--pyruvic transaminase

multiple interactions

EXP
ISO

caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein]
caffeic acid inhibits the reaction [Acetaminophen results in increased activity of GPT protein]

PMID:15212457 PMID:27720869

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione-disulfide reductase

multiple interactions

EXP
ISO

caffeic acid inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]

PMID:19442820 PMID:21640567 PMID:22036979

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase mu 1

decreases activity

EXP

caffeic acid results in decreased activity of GSTM1 protein

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

decreases activity

EXP

caffeic acid results in decreased activity of GSTM2 protein

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase pi 1

decreases activity

EXP

caffeic acid results in decreased activity of GSTP1 protein

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glucuronidase, beta

multiple interactions

EXP

caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]

NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

multiple interactions

EXP

caffeic acid inhibits the reaction [Cisplatin results in decreased activity of H6PD protein]

NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125

G

hepatitis A virus cellular receptor 2

multiple interactions

ISO

[resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of HAVCR2 mRNA

NCBI chr10:31,383,801...31,415,334
Ensembl chr10:31,383,925...31,413,872

G

hes family bHLH transcription factor 1

multiple interactions

EXP

caffeic acid inhibits the reaction [Valproic Acid results in increased expression of HES1 mRNA]

NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061

G

holocarboxylase synthetase

decreases activity

ISO

caffeic acid results in decreased activity of HLCS protein

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

ISO

caffeic acid results in decreased expression of HMGCR mRNA

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

heat shock protein 90 beta family member 1

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293

G

heat shock protein family E (Hsp10) member 1

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

interferon gamma

increases expression
multiple interactions

ISO
EXP

caffeic acid results in increased expression of IFNG protein
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of IFNG protein]

PMID:27378625 PMID:29968957

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interleukin 10

decreases expression

ISO

caffeic acid results in decreased expression of IL10 protein

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 1 beta

multiple interactions

ISO
EXP

caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL1B protein]

PMID:27368151 PMID:27720869

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 2

increases expression

ISO

caffeic acid results in increased expression of IL2 protein

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672

G

interleukin 21 receptor

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA]

NCBI chr 1:189,598,682...189,626,340
Ensembl chr 1:189,598,558...189,626,342

G

interleukin 4

decreases expression

ISO

caffeic acid results in decreased expression of IL4 protein

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

interleukin 6

increases expression
multiple interactions

ISO
EXP

caffeic acid results in increased expression of IL6 mRNA
caffeic acid inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL6 protein]

PMID:21870829 PMID:27368151 PMID:27720869 PMID:28299617

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

kinesin family member 15

multiple interactions

ISO

[Thapsigargin co-treated with caffeic acid] results in increased expression of KIF15 mRNA

NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202

G

kinesin family member 20B

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]

NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451

G

kinesin family member 2C

multiple interactions

ISO

caffeic acid inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA]

NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212

G

monoamine oxidase A

decreases activity

ISO

caffeic acid results in decreased activity of MAOA protein

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631

G

monoamine oxidase B

decreases activity

ISO

caffeic acid results in decreased activity of MAOB protein

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375

G

mitogen activated protein kinase kinase 5

multiple interactions

ISO

[Thapsigargin co-treated with caffeic acid] results in decreased expression of MAP2K5 mRNA

NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373

G

mitogen activated protein kinase 1

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitofusin 1

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MFN1 mRNA]

NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190

G

microsomal glutathione S-transferase 1

increases activity

EXP

caffeic acid results in increased activity of MGST1 protein

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

myeloperoxidase

multiple interactions
decreases activity

ISO
EXP

caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]
caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]]
caffeic acid results in decreased activity of MPO protein

PMID:22036979 PMID:24060682 PMID:33301711

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

mitochondrial ribosomal protein L45

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRPL45 mRNA]

NCBI chr10:82,805,039...82,816,862
Ensembl chr10:82,804,874...82,816,139

G

mitochondrial ribosome recycling factor

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA]

NCBI chr 3:39,884,530...39,941,317
Ensembl chr 3:39,884,359...39,967,397

G

mitochondrially encoded cytochrome c oxidase II

multiple interactions

ISO

[caffeic acid co-treated with Zymosan] results in increased expression of COX2 protein; caffeic acid inhibits the reaction [Zymosan results in increased expression of COX2 protein]

NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674

G

norrin cystine knot growth factor NDP

increases expression

ISO

caffeic acid results in increased expression of NDP mRNA

NCBI chr X:8,379,569...8,404,019
Ensembl chr X:8,379,569...8,406,802

G

nitric oxide synthase 2

multiple interactions

EXP
ISO

caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOS2 protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

PMID:29968957 PMID:31306686

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

nitric oxide synthase 3

increases expression

ISO

caffeic acid results in increased expression of NOS3 mRNA

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

notch receptor 1

multiple interactions

EXP

caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA]

NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613

G

5' nucleotidase, ecto

multiple interactions
decreases activity

EXP

caffeic acid inhibits the reaction [Caffeine results in decreased activity of NT5E protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of NT5E protein]

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645

G

programmed cell death 10

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PDCD10 mRNA]

NCBI chr 2:162,602,516...162,644,690
Ensembl chr 2:162,602,516...162,644,612

G

phosphogluconate dehydrogenase

decreases activity

ISO

caffeic acid results in decreased activity of PGD protein

NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029

G

phosphoinositide-3-kinase regulatory subunit 1

increases expression

ISO

caffeic acid results in increased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

polo-like kinase 1

multiple interactions

ISO

[Thapsigargin co-treated with caffeic acid] results in increased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637

G

polo-like kinase 4

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of PLK4 mRNA]

NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892

G

peroxisome proliferator-activated receptor gamma

increases expression

ISO

caffeic acid results in increased expression of PPARG mRNA

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

peroxiredoxin 5

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PRDX5 mRNA]

NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020

G

prostaglandin-endoperoxide synthase 2

multiple interactions

ISO

caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTGS2 mRNA]

PMID:19442820 PMID:22036979 PMID:31306686

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

pentraxin 3

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTX3 mRNA]

NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372

G

Raf-1 proto-oncogene, serine/threonine kinase

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein]

NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

EXP

caffeic acid inhibits the reaction [Valproic Acid results in increased expression of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

stearoyl-CoA desaturase

multiple interactions

ISO

[Metformin co-treated with caffeic acid] results in decreased expression of SCD1 protein

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

serpin family E member 1

multiple interactions

ISO

caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein]

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

sideroflexin 4

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in decreased expression of SFXN4 mRNA]

NCBI chr 1:269,962,527...269,984,849
Ensembl chr 1:269,962,535...269,984,836

G

solute carrier family 2 member 2

increases expression

ISO

caffeic acid results in increased expression of SLC2A2 mRNA

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467

G

solute carrier family 2 member 4

increases expression

ISO

caffeic acid results in increased expression of SLC2A4 mRNA

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270

G

solute carrier family 5 member 1

increases expression

ISO

caffeic acid results in increased expression of SLC5A1 mRNA

NCBI chr14:81,778,495...81,843,084
Ensembl chr14:81,778,348...81,846,624

G

synuclein alpha

multiple interactions

ISO

caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein]

NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315

G

sterol regulatory element binding transcription factor 1

multiple interactions

ISO

[Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

serine/threonine kinase 32A

multiple interactions

ISO

[Thapsigargin co-treated with caffeic acid] results in decreased expression of STK32A mRNA

NCBI chr18:35,509,791...35,620,421
Ensembl chr18:35,509,982...35,628,985

G

sulfotransferase family 1A member 1

increases sulfation

ISO

SULT1A1 protein results in increased sulfation of caffeic acid

NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131

G

sulfotransferase family 1C member 2A

increases sulfation

ISO

SULT1C2 protein results in increased sulfation of caffeic acid

NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132

G

tumor necrosis factor

increases expression
multiple interactions

ISO
EXP

caffeic acid results in increased expression of TNF mRNA
caffeic acid inhibits the reaction [Aluminum results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Valproic Acid results in increased expression of TNF protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]

PMID:21870829 PMID:22036979 PMID:27368151 PMID:29968957 PMID:31306686

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

tumor protein p53

affects expression
multiple interactions

ISO

caffeic acid affects the expression of TP53 protein
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]

PMID:11522280 PMID:19442820

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tyrosinase

increases oxidation
multiple interactions

ISO

TYR protein results in increased oxidation of caffeic acid
[TYR protein results in increased oxidation of caffeic acid] which results in decreased abundance of Glutathione

NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857

G

ubiquitin-conjugating enzyme E2C

multiple interactions

ISO

caffeic acid promotes the reaction [Thapsigargin results in increased expression of UBE2C mRNA]

NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678

G

UDP glucuronosyltransferase family 1 member A1

decreases activity

ISO

caffeic acid results in decreased activity of UGT1A1 protein

NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases glucuronidation
decreases activity

ISO

UGT1A3 protein results in increased glucuronidation of caffeic acid
caffeic acid results in decreased activity of UGT1A3 protein

PMID:15117964 PMID:35868516

NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 1 member A6a

decreases activity

ISO

caffeic acid results in decreased activity of UGT1A6 protein

NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 1 member A9

decreases activity

ISO

caffeic acid results in decreased activity of UGT1A9 protein

NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase 2 family, polypeptide B1

decreases activity

ISO

caffeic acid results in decreased activity of UGT2B17 protein

NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331

G

UDP glucuronosyltransferase family 2 member B7

decreases activity

ISO

caffeic acid results in decreased activity of UGT2B7 protein

NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451

G

vascular endothelial growth factor A

decreases secretion

ISO

caffeic acid results in decreased secretion of VEGFA protein

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

xanthine dehydrogenase

multiple interactions

ISO

caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

insulin 2

increases secretion

ISO

Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

multiple interactions

ISO

ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

ADAM metallopeptidase domain 9

multiple interactions

ISO

ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein]

NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646

G

alpha-fetoprotein

multiple interactions

EXP

ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA]

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

aminolevulinate dehydratase

multiple interactions
decreases activity

EXP
ISO

Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein]
ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]

PMID:14630126 PMID:17624921 PMID:23933410

NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041

G

arachidonate 5-lipoxygenase

decreases activity

ISO

ebselen results in decreased activity of ALOX5 protein

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

BCL2 associated X, apoptosis regulator

multiple interactions

EXP

ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein]

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL2, apoptosis regulator

multiple interactions

EXP

ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

caspase 3

multiple interactions
increases activity

ISO
EXP

ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein]
ebselen results in increased activity of CASP3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]

PMID:21300091 PMID:23649643 PMID:25068500 PMID:30558456

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 9

multiple interactions

ISO
EXP

ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]
ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]

PMID:18629305 PMID:23649643

Ensembl chr 5:159,391,188...159,409,648

G

catalase

increases activity
multiple interactions

EXP

ebselen results in increased activity of CAT protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]

PMID:27282967 PMID:30558456

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cytochrome c oxidase subunit 4i1

increases expression

ISO

ebselen results in increased expression of COX4I1 protein

NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624

G

citrate synthase

multiple interactions

ISO
EXP

ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]
ebselen inhibits the reaction [Cisplatin results in decreased activity of CS protein]

PMID:27385396 PMID:32860823

NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

EXP

ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

eukaryotic translation initiation factor 2 subunit alpha

increases phosphorylation

EXP

ebselen results in increased phosphorylation of EIF2S1 protein

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649

G

epoxide hydrolase 2

multiple interactions

ISO

ebselen binds to and results in decreased activity of EPHX2 protein

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

fragile X messenger ribonucleoprotein 1

multiple interactions

ISO

ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]

NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein]

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

glucose-6-phosphatase catalytic subunit 1

multiple interactions

EXP

ebselen inhibits the reaction [Cisplatin results in increased activity of G6PC1 protein]

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

glucokinase

multiple interactions

ISO

[ebselen co-treated with Glucose] results in increased activity of GCK protein

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glial fibrillary acidic protein

increases phosphorylation

EXP

ebselen results in increased phosphorylation of GFAP protein

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

gap junction protein, alpha 1

multiple interactions

EXP

ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein]

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689

G

glutathione peroxidase 1

multiple interactions

ISO

ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]

PMID:23795780 PMID:28383113

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione-disulfide reductase

increases activity
multiple interactions

EXP

ebselen results in increased activity of GSR protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]

PMID:27282967 PMID:30558456

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase alpha 1

multiple interactions

EXP

ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528

G

glutathione S-transferase alpha 3

multiple interactions

EXP

ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein

NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654

G

glutathione S-transferase mu 1

multiple interactions

EXP

ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

multiple interactions

EXP

ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase pi 1

multiple interactions

EXP

ebselen binds to and results in decreased activity of GSTP1 protein

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

ISO

ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

heme oxygenase 1

multiple interactions

EXP

[ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

hematopoietic prostaglandin D synthase

increases expression

ISO

ebselen results in increased expression of HPGDS mRNA

NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501

G

heat shock transcription factor 1

increases activity

ISO

ebselen results in increased activity of HSF1 protein

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665

G

interferon gamma

multiple interactions

ISO

ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interleukin 6

multiple interactions

EXP

ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

insulin 1

multiple interactions

ISO

ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen promotes the reaction [Glucose results in increased secretion of INS1 protein]

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

mitogen activated protein kinase 1

multiple interactions
increases activity
increases phosphorylation

ISO
EXP

ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen results in increased activity of MAPK1 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein

PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions
increases activity
increases phosphorylation

ISO
EXP

ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen results in increased activity of MAPK3 protein
ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]

PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 9

increases phosphorylation

EXP

ebselen results in increased phosphorylation of MAPK9 protein

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228

G

matrix metallopeptidase 13

multiple interactions

EXP

ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA]

NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105

G

nerve growth factor

multiple interactions

ISO

ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

nitric oxide synthase 2

multiple interactions
decreases activity

ISO
EXP

ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
ebselen results in decreased activity of NOS2 protein

PMID:7590103 PMID:12794164

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

NAD(P)H quinone dehydrogenase 1

decreases activity

EXP

ebselen results in decreased activity of NQO1 protein

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

pancreatic and duodenal homeobox 1

multiple interactions

ISO

[ebselen co-treated with Glucose] results in increased expression of PDX1 protein

NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156

G

phosphoethanolamine/phosphocholine phosphatase 1

decreases activity

ISO

ebselen results in decreased activity of PHOSPHO1 protein

NCBI chr10:81,258,810...81,266,345
Ensembl chr10:81,257,427...81,268,481

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

solute carrier family 11 member 2

multiple interactions

ISO

ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]

NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941

G

solute carrier family 2 member 2

multiple interactions

ISO
EXP

[ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein
ebselen inhibits the reaction [Cisplatin results in increased expression of SLC2A2 protein]

PMID:23795780 PMID:32860823

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467

G

SMAD family member 3

multiple interactions

ISO

ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324

G

superoxide dismutase 1

decreases response to substance
multiple interactions

ISO

ebselen results in decreased susceptibility to SOD1 protein mutant form
ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]

PMID:16702190 PMID:23795780

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

multiple interactions

EXP

ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

tyrosine aminotransferase

multiple interactions

EXP

ebselen inhibits the reaction [Cisplatin results in increased activity of TAT protein]

NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482

G

transforming growth factor, beta 1

multiple interactions

EXP
ISO

ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]

PMID:11903743 PMID:16757516 PMID:21131394

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

TIMP metallopeptidase inhibitor 1

multiple interactions

EXP

ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

tumor necrosis factor

multiple interactions

EXP

ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

thioredoxin reductase 1

multiple interactions

ISO

ebselen results in increased expression of and results in increased activity of TXNRD1 protein

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

uncoupling protein 2

multiple interactions

ISO

[ebselen co-treated with Glucose] results in decreased expression of UCP2 protein

NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743

G

X-box binding protein 1

increases phosphorylation

EXP

ebselen results in increased phosphorylation of XBP1 protein

NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706

G

XPA, DNA damage recognition and repair factor

multiple interactions

ISO

ebselen inhibits the reaction [Zinc binds to XPA protein]

NCBI chr 5:65,227,281...65,275,784
Ensembl chr 5:65,227,281...65,272,425

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acid phosphatase 3

increases expression

ISO

Ellagic Acid results in increased expression of ACP3 mRNA

NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033

G

acid phosphatase 5, tartrate resistant

multiple interactions

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929

G

angiotensinogen

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in decreased abundance of NADP]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

angiotensin II receptor, type 1a

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]

NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660

G

apoptosis inducing factor, mitochondria associated 1

increases expression

ISO

Ellagic Acid results in increased expression of AIFM1 protein

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions

ISO
EXP

Ellagic Acid results in increased phosphorylation of AKT1 protein
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of AKT1 protein]

PMID:26986492 PMID:35236242

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

albumin

multiple interactions
affects binding

ISO

ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein

PMID:6343536 PMID:25247703

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase

decreases activity

ISO

Ellagic Acid results in decreased activity of ALKBH2 protein

NCBI chr12:48,156,825...48,161,489
Ensembl chr12:48,156,827...48,161,483

G

alkaline phosphatase, biomineralization associated

increases expression

ISO

Ellagic Acid results in increased expression of ALPL mRNA

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

apoptotic peptidase activating factor 1

decreases expression
increases expression

ISO

Ellagic Acid results in decreased expression of APAF1 mRNA
Ellagic Acid results in increased expression of APAF1 mRNA

PMID:12002526 PMID:35179410

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772

G

amyloid beta precursor protein

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of APP protein]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

achaete-scute family bHLH transcription factor 1

increases expression

ISO

Ellagic Acid results in increased expression of ASCL1 mRNA

NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:23,790,360...23,798,231

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

ISO

Ellagic Acid results in increased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050

G

activating transcription factor 3

increases expression

ISO

Ellagic Acid results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

autophagy related 5

increases expression

ISO

Ellagic Acid results in increased expression of ATG5 mRNA

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821

G

BCL2-associated agonist of cell death

increases expression

ISO

Ellagic Acid results in increased expression of BAD protein

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

EXP
ISO

Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA]
Ellagic Acid results in increased expression of BAX mRNA

PMID:29854611 PMID:35179410

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL2, apoptosis regulator

increases expression
decreases expression
multiple interactions

ISO
EXP

Ellagic Acid results in increased expression of BCL2 protein
Ellagic Acid results in decreased expression of BCL2 mRNA
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]

PMID:20103723 PMID:22386815 PMID:29854611 PMID:35179410 PMID:35236242

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

bone morphogenetic protein 6

decreases expression

ISO

Ellagic Acid results in decreased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261

G

BRF1 general transcription factor IIIB subunit

decreases expression

ISO

Ellagic Acid results in decreased expression of BRF1 mRNA

NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386

G

calreticulin

decreases expression

ISO

Ellagic Acid results in decreased expression of CALR mRNA

NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236

G

caspase 3

increases expression
multiple interactions
increases activity
decreases activity
decreases expression

ISO
EXP

Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in decreased expression of CASP3 mRNA

PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 9

multiple interactions

ISO

Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein

Ensembl chr 5:159,391,188...159,409,648

G

catalase

increases activity
multiple interactions

EXP

Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]

PMID:20074268 PMID:24877639 PMID:29864931 PMID:35236242 PMID:36108929

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 2

decreases secretion

ISO

Ellagic Acid results in decreased secretion of CCL2 protein

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

cyclin G1

decreases expression

EXP

ellagic acid inhibits the reaction [estrogen increases expression of Ccng1 mRNA and protein in rat mammary tissue]

RGD

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

CD14 molecule

decreases expression

ISO

Ellagic Acid results in decreased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

cyclin-dependent kinase 1

decreases expression

ISO

Ellagic Acid results in decreased expression of CDK1 protein

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

ISO

[resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]]
Ellagic Acid results in increased expression of CDKN1A protein

PMID:15735102 PMID:20103723 PMID:23554011

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

collagen type I alpha 1 chain

increases expression

ISO

Ellagic Acid results in increased expression of COL1A1 mRNA; Ellagic Acid results in increased expression of COL1A1 protein

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

cathepsin D

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin K

multiple interactions

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cytochrome b-245 alpha chain

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA]

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases expression
decreases activity

ISO

Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein

PMID:19329757 PMID:20816778

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases activity
multiple interactions

ISO

Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]

PMID:19329757 PMID:20103723

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

death-domain associated protein

decreases expression

ISO

Ellagic Acid results in decreased expression of DAXX mRNA

NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720

G

DNA fragmentation factor subunit alpha

decreases expression

ISO

Ellagic Acid results in decreased expression of DFFA mRNA

NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728

G

E4F transcription factor 1

increases expression

ISO

Ellagic Acid results in increased expression of E4F1 mRNA

NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,978,990...13,990,506

G

early growth response 3

decreases expression

ISO

Ellagic Acid results in decreased expression of EGR3 mRNA

NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712

G

endonuclease G

increases expression

ISO

Ellagic Acid results in increased expression of ENDOG protein

NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573

G

E1A binding protein p300

increases expression

ISO

Ellagic Acid results in increased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

epidermal growth factor receptor pathway substrate 15

increases expression

ISO

Ellagic Acid results in increased expression of EPS15 mRNA

NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

increases expression

ISO

Ellagic Acid results in increased expression of EZH1 mRNA

NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620

G

coagulation factor XII

multiple interactions
increases activity

ISO

ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]

NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664

G

Fibroblast growth factor receptor 1

decreases expression

ISO

Ellagic Acid results in decreased expression of FGFR1 mRNA

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

filamin A

decreases expression

ISO

Ellagic Acid results in decreased expression of FLNA mRNA

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

fibronectin 1

multiple interactions

EXP

Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]

PMID:20103723 PMID:32971123

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

glucose-6-phosphate dehydrogenase

decreases activity

ISO

Ellagic Acid results in decreased activity of G6PD protein

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

galanin and GMAP prepropeptide

multiple interactions

EXP

Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein]

NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

ISO

Ellagic Acid results in decreased expression of GPLD1 mRNA

NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975

G

glutamic--pyruvic transaminase

multiple interactions

EXP
ISO

Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein]
Ellagic Acid inhibits the reaction [Diquat results in increased activity of GPT protein]

PMID:24877639 PMID:29935397 PMID:35268077

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 1

multiple interactions

EXP
ISO

Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA]

PMID:29935397 PMID:35268077

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione-disulfide reductase

multiple interactions

EXP

Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase alpha 4

increases expression

ISO

Ellagic Acid results in increased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase theta 1

affects expression

EXP

Ellagic Acid affects the expression of GSTT1 protein

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019

G

general transcription factor IIE subunit 2

increases expression

ISO

Ellagic Acid results in increased expression of GTF2E2 mRNA

NCBI chr16:65,102,386...65,152,563
Ensembl chr16:65,102,390...65,161,394

G

general transcription factor 2H subunit 4

increases expression

ISO

Ellagic Acid results in increased expression of GTF2H4 mRNA

NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760

G

glucuronidase, beta

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]

NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024

G

hypoxia inducible factor 1 subunit alpha

decreases expression

ISO

Ellagic Acid results in decreased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

holocarboxylase synthetase

decreases activity

ISO

Ellagic Acid results in decreased activity of HLCS protein

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

heme oxygenase 1

increases expression
multiple interactions

ISO

Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein

PMID:22386815 PMID:23546295 PMID:35268077

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

HRas proto-oncogene, GTPase

multiple interactions

ISO

[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

immediate early response 2

increases expression

ISO

Ellagic Acid results in increased expression of IER2 mRNA

NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708

G

interferon gamma

multiple interactions

EXP

Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein]

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

insulin-like growth factor binding protein 2

increases expression

ISO

Ellagic Acid results in increased expression of IGFBP2 mRNA

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171

G

insulin-like growth factor binding protein 4

decreases expression

ISO

Ellagic Acid results in decreased expression of IGFBP4 mRNA

NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473

G

interleukin 1 beta

decreases expression
multiple interactions

ISO
EXP

Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]

PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor type 1

decreases expression

ISO

Ellagic Acid results in decreased expression of IL1R1 mRNA

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579

G

interleukin 6

multiple interactions

EXP

Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein]

PMID:21762681 PMID:24877639 PMID:27965107

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

inositol polyphosphate-5-phosphatase D

increases expression

ISO

Ellagic Acid results in increased expression of INPP5D mRNA

NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589

G

IQ motif containing GTPase activating protein 2

increases expression

ISO

Ellagic Acid results in increased expression of IQGAP2 mRNA

NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649

G

interferon regulatory factor 9

increases expression

ISO

Ellagic Acid results in increased expression of IRF9 mRNA

NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression

ISO

Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

kallikrein 1-related peptidase C10

decreases expression

ISO

Ellagic Acid results in decreased expression of KLK3 mRNA

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586

G

lipopolysaccharide-induced TNF factor

increases expression

ISO

Ellagic Acid results in increased expression of LITAF mRNA

NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930

G

microtubule-associated protein 1A

decreases expression

ISO

Ellagic Acid results in decreased expression of MAP1A mRNA

NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159

G

mitogen-activated protein kinase kinase kinase 1

decreases expression

ISO

Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein

NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897

G

mitogen activated protein kinase 1

multiple interactions

ISO
EXP

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]

PMID:32971123 PMID:38356441

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen-activated protein kinase 11

increases expression

ISO

Ellagic Acid results in increased expression of MAPK11 mRNA

NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038

G

mitogen activated protein kinase 14

multiple interactions

EXP

Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein]

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

multiple interactions

ISO
EXP

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]

PMID:32971123 PMID:38356441

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

multiple interactions

ISO

[Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 9

multiple interactions

ISO

[Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228

G

microsomal glutathione S-transferase 1

decreases activity

EXP

Ellagic Acid results in decreased activity of MGST1 protein

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

microRNA 140

multiple interactions

EXP

ellagic acid inhibits the reaction [hypoxia and acute myocardial infarction decreases expression of mir140 RNA in cardiac muscle cells]

RGD

NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391

G

monocyte to macrophage differentiation-associated

increases expression

ISO

Ellagic Acid results in increased expression of MMD mRNA

NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609

G

matrix metallopeptidase 2

multiple interactions
decreases expression
decreases activity

ISO

Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein]
Ellagic Acid results in decreased expression of MMP2 mRNA
Ellagic Acid results in decreased activity of MMP2 protein

PMID:21573219 PMID:35179410

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 9

decreases expression
decreases activity

ISO

Ellagic Acid results in decreased expression of MMP9 mRNA
Ellagic Acid results in decreased activity of MMP9 protein

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

myosin heavy chain 7

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA]

NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194

G

neutrophil cytosolic factor 2

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA]

NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149

G

nuclear factor of activated T-cells 1

multiple interactions

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]

NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990

G

NFE2 like bZIP transcription factor 2

affects localization
multiple interactions
increases expression
affects response to substance

ISO
EXP

Ellagic Acid affects the localization of NFE2L2 protein
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]
Ellagic Acid results in increased expression of NFE2L2 mRNA
[Ellagic Acid co-treated with Diquat] results in increased expression of NFE2L2 mRNA; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid

PMID:22386815 PMID:23546295 PMID:30503583 PMID:35236242 PMID:35268077

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor kappa B subunit 2

decreases expression

ISO

Ellagic Acid results in decreased expression of NFKB2 mRNA

PMID:12002526 PMID:35179410

NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637

G

neuronatin

increases expression

ISO

Ellagic Acid results in increased expression of NNAT mRNA

NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086

G

NOP56 ribonucleoprotein

decreases expression

ISO

Ellagic Acid results in decreased expression of NOP56 mRNA

NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959

G

nitric oxide synthase 2

multiple interactions
decreases expression

EXP
ISO

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]
Ellagic Acid results in decreased expression of NOS2 mRNA

PMID:28815802 PMID:35179410 PMID:38356441

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

neuronal PAS domain protein 2

increases expression

ISO

Ellagic Acid results in increased expression of NPAS2 mRNA

NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037

G

natriuretic peptide A

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]

NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493

G

natriuretic peptide B

multiple interactions

EXP

Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA]

NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions

ISO

Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein

PMID:23546295 PMID:35268077

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group I, member 3

increases activity

ISO

Ellagic Acid results in increased activity of NR1I3 protein

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

poly (ADP-ribose) glycohydrolase

decreases activity

ISO

Ellagic Acid results in decreased activity of PARG protein

NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584

G

poly (ADP-ribose) polymerase 1

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

proliferating cell nuclear antigen

multiple interactions

ISO

[resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA]

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

protein disulfide isomerase family A, member 2

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein]

NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396

G

phosphogluconate dehydrogenase

decreases activity

ISO

Ellagic Acid results in decreased activity of PGD protein

NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029

G

phospholipase A2 group IIA

decreases expression

ISO

Ellagic Acid results in decreased expression of PLA2G2A mRNA

NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297

G

proteolipid protein 2

increases expression

ISO

Ellagic Acid results in increased expression of PLP2 mRNA

NCBI chr X:17,506,153...17,509,552
Ensembl chr X:17,506,059...17,509,550

G

PML nuclear body scaffold

decreases expression

ISO

Ellagic Acid results in decreased expression of PML mRNA

NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083

G

peroxisome proliferator-activated receptor delta

decreases expression

ISO

Ellagic Acid results in decreased expression of PPARD mRNA

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707

G

peroxisome proliferator-activated receptor gamma

increases expression

ISO

Ellagic Acid results in increased expression of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

multiple interactions
decreases expression

ISO

Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
Ellagic Acid results in decreased expression of PPARGC1A mRNA

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

protein kinase cGMP-dependent 1

decreases expression

ISO

Ellagic Acid results in decreased expression of PRKG1 mRNA

NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005

G

pleiotrophin

decreases expression
increases expression

ISO

Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

protein tyrosine phosphatase, receptor type N2

increases expression

ISO

Ellagic Acid results in increased expression of PTPRN2 mRNA

NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744

G

RAN, member RAS oncogene family

decreases expression

ISO

Ellagic Acid results in decreased expression of RAN mRNA

NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317

G

RB transcriptional corepressor 1

multiple interactions

EXP

Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein]

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

reversion-inducing-cysteine-rich protein with kazal motifs

increases expression
multiple interactions

ISO

Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]

NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270

G

RELA proto-oncogene, NF-kB subunit

decreases expression
multiple interactions

ISO
EXP

Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein]
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]

PMID:12002526 PMID:24877639 PMID:27473819 PMID:27965107 PMID:32971123 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

regulator of G-protein signaling 5

decreases expression

ISO

Ellagic Acid results in decreased expression of RGS5 mRNA

NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352

G

RUNX family transcription factor 2

increases expression

ISO

Ellagic Acid results in increased expression of RUNX2 mRNA; Ellagic Acid results in increased expression of RUNX2 protein

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027

G

stearoyl-CoA desaturase

decreases expression

ISO

Ellagic Acid results in decreased expression of SCD mRNA

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

septin 2

increases expression

ISO

Ellagic Acid results in increased expression of SEPTIN2 mRNA

NCBI chr 9:101,465,535...101,498,766
Ensembl chr 9:101,465,650...101,498,759

G

superoxide dismutase 1

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 mRNA]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 protein]

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

multiple interactions

EXP

Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

superoxide dismutase 3

decreases expression

ISO

Ellagic Acid results in decreased expression of SOD3 mRNA

NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125

G

Sp7 transcription factor

increases expression

ISO

Ellagic Acid results in increased expression of SP7 mRNA; Ellagic Acid results in increased expression of SP7 protein

NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559

G

secreted phosphoprotein 1

increases expression

ISO

Ellagic Acid results in increased expression of SPP1 mRNA; Ellagic Acid results in increased expression of SPP1 protein

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462

G

steroidogenic acute regulatory protein

increases expression
multiple interactions

ISO

Ellagic Acid results in increased expression of STAR mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

signal transducer and activator of transcription 3

increases expression
decreases expression

ISO

Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA

PMID:12002526 PMID:20816778

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

TATA-box binding protein associated factor, RNA polymerase 1 subunit C

decreases expression

ISO

Ellagic Acid results in decreased expression of TAF1C mRNA

NCBI chr19:64,561,079...64,567,599
Ensembl chr19:64,560,562...64,567,599

G

transcription factor 12

increases expression

ISO

Ellagic Acid results in increased expression of TCF12 mRNA

NCBI chr 8:81,371,201...81,682,337
Ensembl chr 8:81,373,321...81,679,922

G

telomerase reverse transcriptase

multiple interactions
increases expression

ISO
EXP

Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein]
Ellagic Acid results in increased expression of TERT mRNA alternative form

PMID:19501078 PMID:27965107

NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111

G

transcription factor A, mitochondrial

decreases expression

ISO

Ellagic Acid results in decreased expression of TFAM mRNA

NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877

G

transforming growth factor, beta 1

increases expression
multiple interactions

ISO
EXP

Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]

PMID:12002526 PMID:24877639

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

tumor necrosis factor

multiple interactions
decreases expression

EXP
ISO

Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [TNF protein results in increased activity of and affects the secretion of CXCL8 protein]
Ellagic Acid results in decreased expression of TNF mRNA

PMID:21762681 PMID:24877639 PMID:27473819 PMID:27965107 PMID:28815802 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 11A

multiple interactions
affects binding

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]
Ellagic Acid binds to TNFRSF11A protein

NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257

G

TNF superfamily member 11

multiple interactions
affects binding

ISO

Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid binds to TNFSF11 protein

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

troponin T2, cardiac type

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]

NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125

G

tumor protein p53

increases expression
multiple interactions

ISO
EXP

Ellagic Acid results in increased expression of TP53 mRNA; Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]

PMID:15735102 PMID:23554011 PMID:27965107 PMID:35179410

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

UDP-glucose pyrophosphorylase 2

decreases expression

ISO

Ellagic Acid results in decreased expression of UGP2 mRNA

NCBI chr14:99,657,637...99,698,573
Ensembl chr14:99,657,639...99,698,002

G

ubiquitin specific peptidase 4

decreases expression

ISO

Ellagic Acid results in decreased expression of USP4 mRNA

NCBI chr 8:117,912,576...117,957,934
Ensembl chr 8:117,914,614...117,957,949

G

vascular endothelial growth factor A

multiple interactions

EXP

Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of VEGFA protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

tryptophanyl-tRNA synthetase 1

increases expression

ISO

Ellagic Acid results in increased expression of WARS1 mRNA

NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645

G

WEE1 G2 checkpoint kinase

decreases expression

ISO

Ellagic Acid results in decreased expression of WEE1 protein

NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449

G

zinc finger and BTB domain containing 16

decreases expression

ISO

Ellagic Acid results in decreased expression of ZBTB16 mRNA

NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507

G

zinc finger MYM-type containing 2

increases expression

ISO

Ellagic Acid results in increased expression of ZMYM2 mRNA

NCBI chr15:35,151,356...35,224,528
Ensembl chr15:35,127,994...35,224,941

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 1

multiple interactions
decreases response to substance

ISO

GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Ethacrynic Acid]

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily C member 2

increases transport

ISO

ABCC2 protein results in increased transport of Ethacrynic Acid

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

aldo-keto reductase family 1, member C1

increases expression

ISO

Ethacrynic Acid results in increased expression of AKR1C1 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

aldo-keto reductase family 7, member A2

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein]

NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109

G

Bcl2-like 1

increases expression
multiple interactions

ISO

Ethacrynic Acid results in increased expression of BCL2L1 protein
[arsenic trioxide co-treated with Ethacrynic Acid] results in increased expression of BCL2L1 protein

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

baculoviral IAP repeat-containing 5

multiple interactions

ISO

[arsenic trioxide co-treated with Ethacrynic Acid] results in decreased expression of BIRC5 protein

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

caspase 3

multiple interactions

ISO

[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein; [MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with arsenic trioxide]] which results in increased cleavage of CASP3 protein; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 8

multiple interactions
increases cleavage

ISO

[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP8 protein
Ethacrynic Acid results in increased cleavage of CASP8 protein

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 9

increases cleavage
multiple interactions

ISO

Ethacrynic Acid results in increased cleavage of CASP9 protein
arsenic trioxide promotes the reaction [Ethacrynic Acid results in increased cleavage of CASP9 protein]; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; MCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]

Ensembl chr 5:159,391,188...159,409,648

G

catalase

multiple interactions

ISO

CAT mutant form promotes the reaction [arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

carbonyl reductase 1

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]

NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104

G

cyclin D1

decreases expression

ISO

Ethacrynic Acid results in decreased expression of CCND1 mRNA

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

Ethacrynic Acid results in increased expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

CASP8 and FADD-like apoptosis regulator

multiple interactions
decreases expression

ISO

arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of CFLAR protein]

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions

ISO
EXP

Ethacrynic Acid results in increased expression of CYP1A1 mRNA
Ethacrynic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]

PMID:9973208 PMID:18493746

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

ISO

Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of DDIT3 mRNA]; Glutathione inhibits the reaction [Ethacrynic Acid results in increased expression of DDIT3 mRNA]
Ethacrynic Acid results in increased expression of DDIT3 mRNA; Ethacrynic Acid results in increased expression of DDIT3 protein

PMID:17171638 PMID:25817893 PMID:35724838

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

fibronectin 1

decreases expression

ISO

Ethacrynic Acid results in decreased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Ethacrynic Acid results in increased expression of FOS mRNA

PMID:10407097 PMID:12946577

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

frizzled class receptor 5

increases expression

ISO

Ethacrynic Acid results in increased expression of FZD5 mRNA

NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

ISO

[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Ethacrynic Acid

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

multiple interactions

ISO

[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Ethacrynic Acid

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

glutathione S-transferase alpha 1

decreases response to substance
increases expression
multiple interactions
affects metabolic processing

ISO
EXP

GSTA1 protein results in decreased susceptibility to Ethacrynic Acid
Ethacrynic Acid results in increased expression of GSTA1 mRNA
[GSTA1 protein binds to GSTA2 protein] which affects the metabolism of Ethacrynic Acid
GSTA1 protein affects the metabolism of Ethacrynic Acid analog

PMID:1985777 PMID:9799558 PMID:9877184 PMID:12781783

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528

G

glutathione S-transferase alpha 2

affects metabolic processing
multiple interactions

EXP

GSTA2 protein affects the metabolism of Ethacrynic Acid
[GSTA1 protein binds to GSTA2 protein] which affects the metabolism of Ethacrynic Acid

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 4

increases expression
affects metabolic processing

EXP

Ethacrynic Acid results in increased expression of GSTA4 mRNA; Ethacrynic Acid results in increased expression of GSTA4 protein
GSTA4 protein affects the metabolism of Ethacrynic Acid

PMID:2619714 PMID:9799558

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase mu 1

affects metabolic processing

ISO

GSTM1 protein affects the metabolism of Ethacrynic Acid

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase pi 1

decreases activity
affects metabolic processing
decreases response to substance
increases expression
multiple interactions

ISO
EXP

Ethacrynic Acid analog results in decreased activity of GSTP1 protein; Ethacrynic Acid results in decreased activity of GSTP1 protein
GSTP1 protein affects the metabolism of Ethacrynic Acid
GSTP1 protein results in decreased susceptibility to Ethacrynic Acid
GSTP1 protein affects the metabolism of Ethacrynic Acid analog
Ethacrynic Acid results in increased expression of GSTP1 protein
Ethacrynic Acid binds to and results in decreased activity of GSTP1 protein; Ethacrynic Acid inhibits the reaction [Chlorophyllides inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]]; Ethacrynic Acid inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Ethacrynic Acid]; GSTP1 protein results in decreased susceptibility to [arsenic trioxide co-treated with Ethacrynic Acid]; Pyrimethamine inhibits the reaction [GSTP1 protein affects the metabolism of and results in decreased activity of Ethacrynic Acid]; Quinidine inhibits the reaction [GSTP1 protein affects the metabolism of and results in decreased activity of Ethacrynic Acid]; Quinine inhibits the reaction [GSTP1 protein affects the metabolism of and results in decreased activity of Ethacrynic Acid]; Tetracycline inhibits the reaction [GSTP1 protein affects the metabolism of and results in decreased activity of Ethacrynic Acid]

PMID:2619714 PMID:2747627 PMID:9463521 PMID:9806904 PMID:9877184 More...

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase theta 2

affects metabolic processing

EXP

GSTT2 protein affects the metabolism of Ethacrynic Acid

NCBI chr20:12,819,053...12,822,724
Ensembl chr20:12,818,540...12,822,718

G

glutathione S-transferase zeta 1

affects metabolic processing

ISO

GSTZ1 protein affects the metabolism of Ethacrynic Acid

NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233

G

heme oxygenase 1

multiple interactions
increases expression

ISO

Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 protein]
Ethacrynic Acid results in increased expression of HMOX1 mRNA; Ethacrynic Acid results in increased expression of HMOX1 protein

PMID:20934533 PMID:25817893 PMID:26945724 PMID:35724838

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heat shock transcription factor 1

increases activity

ISO

Ethacrynic Acid results in increased activity of HSF1 protein

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665

G

intercellular adhesion molecule 1

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; Ethacrynic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

interleukin 1 beta

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; Ethacrynic Acid inhibits the reaction [IL1B protein affects the localization of RELA protein]; Ethacrynic Acid inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; Ethacrynic Acid inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

[Ethacrynic Acid co-treated with arsenic trioxide] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[Ethacrynic Acid co-treated with arsenic trioxide] results in increased phosphorylation of JUN protein]

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

lymphoid enhancer binding factor 1

decreases expression
affects binding

ISO

Ethacrynic Acid results in decreased expression of LEF1 mRNA
Ethacrynic Acid binds to LEF1 protein

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

mitogen activated protein kinase kinase 1

increases expression

ISO

Ethacrynic Acid results in increased expression of MAP2K1 protein

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184

G

mitogen activated protein kinase 14

decreases expression

ISO

Ethacrynic Acid results in decreased expression of MAPK14 protein

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

increases expression

ISO

Ethacrynic Acid results in increased expression of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

decreases expression

ISO

Ethacrynic Acid results in decreased expression of MAPK8 protein

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

MCL1 apoptosis regulator, BCL2 family member

multiple interactions
decreases expression

ISO

[MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with arsenic trioxide]] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; CAT mutant form promotes the reaction [arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; MCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; MCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with arsenic trioxide]; pyrazolanthrone inhibits the reaction [arsenic trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]

NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782

G

NFE2 like bZIP transcription factor 2

multiple interactions
affects localization
affects response to substance
increases expression

ISO

NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Ethacrynic Acid]
Ethacrynic Acid results in increased expression of and affects the localization of NFE2L2 protein; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of NFE2L2 protein]]
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Ethacrynic Acid
Ethacrynic Acid results in increased expression of NFE2L2 protein

PMID:19303893 PMID:20932822 PMID:20934533 PMID:25817893 PMID:26945724 More...

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NFKB inhibitor alpha

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; Ethacrynic Acid inhibits the reaction [TNF protein affects the localization of NFKBIA protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nerve growth factor

increases expression

ISO

Ethacrynic Acid results in increased expression of NGF mRNA

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

nitric oxide synthase 2

multiple interactions

EXP

Ethacrynic Acid promotes the reaction [Potassium Cyanide results in increased expression of NOS2 protein]

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

poly (ADP-ribose) polymerase 1

multiple interactions

ISO

[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; GSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; MCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [IL1B protein affects the localization of RELA protein]; Ethacrynic Acid inhibits the reaction [TNF protein affects the localization of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

solute carrier family 12 member 2

decreases activity
multiple interactions

ISO

Ethacrynic Acid results in decreased activity of SLC12A2 protein
Ethacrynic Acid inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]

NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470

G

sulfiredoxin 1

increases expression

ISO

Ethacrynic Acid results in increased expression of SRXN1 protein

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

tumor necrosis factor

multiple interactions

ISO

Ethacrynic Acid inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; Ethacrynic Acid inhibits the reaction [TNF protein affects the localization of RELA protein]; Ethacrynic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Ethacrynic Acid inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF alpha induced protein 3

increases expression
multiple interactions

ISO

Ethacrynic Acid results in increased expression of TNFAIP3 protein
Ethacrynic Acid inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; Ethacrynic Acid inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979

G

tumor protein p53

affects localization

ISO

Ethacrynic Acid affects the localization of TP53 protein

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

X-linked inhibitor of apoptosis

multiple interactions

ISO

[arsenic trioxide co-treated with Ethacrynic Acid] results in decreased expression of XIAP protein

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aquaporin 5

decreases expression

EXP

Fosfomycin results in decreased expression of AQP5 protein

NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:132,601,059...132,605,062

G

C-reactive protein

decreases expression

ISO

Fosfomycin results in decreased expression of CRP protein

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

multiple interactions

EXP

GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

mitogen activated protein kinase 1

multiple interactions

EXP

GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

EXP

GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

matrix metallopeptidase 9

multiple interactions

EXP

GGTI-2133 inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]; GGTI-2133 inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

RAP1A, member of RAS oncogene family

decreases geranoylation

ISO

GGTI-2133 results in decreased geranoylation of RAP1A protein

NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

ISO

[Gliotoxin co-treated with ochratoxin A] affects the expression of BAX mRNA
Gliotoxin results in increased expression of BAX mRNA

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

ISO

Gliotoxin results in decreased expression of BCL2 mRNA
[Gliotoxin co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

baculoviral IAP repeat-containing 3

multiple interactions

ISO

Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590

G

caspase 3

multiple interactions
increases expression
increases activity

EXP
ISO

Gliotoxin results in increased cleavage of and results in increased activity of CASP3 protein; Mercuric Chloride inhibits the reaction [Gliotoxin results in increased activity of CASP3 protein]
Gliotoxin results in increased expression of CASP3 mRNA
[Gliotoxin co-treated with ochratoxin A] results in increased expression of CASP3 mRNA

PMID:17466404 PMID:20958918 PMID:39947449

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

cytochrome P450, family 2, subfamily b, polypeptide 2

decreases expression

EXP

Gliotoxin results in decreased expression of CYP2B2 mRNA

NCBI chr 1:90,722,243...90,736,272

G

2,4-dienoyl-CoA reductase 2

decreases expression

EXP

Gliotoxin results in decreased expression of DECR2 mRNA

NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

EXP

Gliotoxin results in increased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

dihydropyrimidinase

decreases expression

EXP

Gliotoxin results in decreased expression of DPYS mRNA

NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142

G

enoyl-CoA hydratase 1

decreases expression

EXP

Gliotoxin results in decreased expression of ECH1 mRNA

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440

G

growth arrest and DNA-damage-inducible, alpha

increases expression

EXP

Gliotoxin results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

gap junction protein, beta 1

decreases expression

EXP

Gliotoxin results in decreased expression of GJB1 mRNA

NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843

G

glycine N-methyltransferase

decreases expression

EXP

Gliotoxin results in decreased expression of GNMT mRNA

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692

G

glutathione S-transferase mu 2

decreases expression

EXP

Gliotoxin results in decreased expression of GSTM2 mRNA

NCBI chr 2:198,312,179...198,316,962

G

histidine ammonia lyase

decreases expression

EXP

Gliotoxin results in decreased expression of HAL mRNA

NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744

G

hypoxia inducible factor 1 subunit alpha

decreases expression

ISO

Gliotoxin results in decreased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

HRas proto-oncogene, GTPase

multiple interactions

ISO

Gliotoxin inhibits the reaction [Acetaminophen results in increased activity of HRAS protein]

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

interferon gamma

decreases expression
decreases secretion

ISO

Gliotoxin results in decreased expression of IFNG mRNA
Gliotoxin results in decreased secretion of IFNG protein

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon-related developmental regulator 1

increases expression

EXP

Gliotoxin results in increased expression of IFRD1 mRNA

NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

Gliotoxin results in increased expression of JUNB mRNA

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218

G

mitogen activated protein kinase 1

multiple interactions

EXP

Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK1 protein

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

EXP

Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

multiple interactions

EXP

Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK8 protein

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mannose binding lectin 1

decreases expression

EXP

Gliotoxin results in decreased expression of MBL1 mRNA

NCBI chr16:17,063,232...17,069,271
Ensembl chr16:17,060,703...17,069,271

G

nuclear factor kappa B subunit 1

multiple interactions

ISO

Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

protein phosphatase 1, regulatory subunit 15A

increases expression

EXP

Gliotoxin results in increased expression of PPP1R15A mRNA

NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

superoxide dismutase 2

multiple interactions

ISO

Gliotoxin inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

sulfotransferase family 1B member 1

decreases expression

EXP

Gliotoxin results in decreased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549

G

tumor necrosis factor

multiple interactions

ISO

Gliotoxin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

alpha tocopherol transfer protein

decreases expression

EXP

Gliotoxin results in decreased expression of TTPA mRNA

NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:38,292,665...38,315,804

G

beta-ureidopropionase 1

decreases expression

EXP

Gliotoxin results in decreased expression of UPB1 mRNA

NCBI chr20:13,216,693...13,243,016
Ensembl chr20:13,216,691...13,277,562

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 1700012B07 gene like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of 1700012B07RIKL gene

NCBI chr10:95,271,034...95,304,337
Ensembl chr10:95,268,422...95,304,315

G

arylacetamide deacetylase

increases expression

ISO

Glyphosate results in increased expression of AADAC protein

NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525

G

AP2 associated kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of AAK1 mRNA

NCBI chr 4:120,845,012...121,009,170
Ensembl chr 4:120,858,557...121,004,236

G

4-aminobutyrate aminotransferase

increases expression
affects methylation

ISO

Glyphosate results in increased expression of ABAT mRNA
Glyphosate affects the methylation of ABAT promoter

PMID:35377194 PMID:36608876

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 2

increases expression

ISO

Glyphosate results in increased expression of ABCA2 mRNA

NCBI chr 3:28,642,660...28,662,689
Ensembl chr 3:28,642,758...28,662,681

G

ATP binding cassette subfamily B member 1A

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 protein

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP binding cassette subfamily B member 5

affects methylation

EXP

Glyphosate affects the methylation of ABCB5 gene

NCBI chr 6:145,978,860...146,075,776
Ensembl chr 6:145,978,906...146,077,039

G

ATP binding cassette subfamily C member 1

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC1 mRNA

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily C member 2

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC2 mRNA

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

ATP binding cassette subfamily C member 6

affects methylation

EXP

Glyphosate affects the methylation of ABCC6 gene

NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895

G

ATP binding cassette subfamily G member 2

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 protein

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

ABHD11 antisense RNA 1

increases expression

EXP

Glyphosate results in increased expression of BICDL3P mRNA

NCBI chr12:27,317,656...27,318,643

G

abhydrolase domain containing 15

increases expression

ISO

Glyphosate results in increased expression of ABHD15 mRNA

NCBI chr10:62,861,335...62,866,726
Ensembl chr10:62,861,317...62,868,540

G

abhydrolase domain containing 16A, phospholipase

increases methylation

EXP

Glyphosate results in increased methylation of ABHD16A gene

NCBI chr20:3,723,756...3,738,617
Ensembl chr20:3,723,757...3,738,736

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression

ISO

Glyphosate results in increased expression of ABHD2 mRNA

NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674

G

ABI family, member 3

increases expression

ISO

Glyphosate results in increased expression of ABI3 mRNA

NCBI chr10:81,266,571...81,277,561
Ensembl chr10:81,266,571...81,277,561

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

increases expression

ISO

Glyphosate results in increased expression of ABL1 mRNA

NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846

G

ankyrin repeat and BTB domain containing 2

increases expression

ISO

Glyphosate results in increased expression of ABTB2 mRNA

NCBI chr 3:110,409,672...110,563,488
Ensembl chr 3:110,409,627...110,563,487

G

ankyrin repeat and BTB domain containing 3

increases methylation

EXP

Glyphosate results in increased methylation of ABTB3 gene

NCBI chr 7:19,922,883...20,199,740
Ensembl chr 7:19,923,814...20,198,110

G

acetyl-CoA carboxylase alpha

increases expression

ISO

Glyphosate results in increased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetyl-CoA carboxylase beta

increases expression

ISO

Glyphosate results in increased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214

G

acyl-CoA dehydrogenase, long chain

decreases expression

ISO

Glyphosate results in decreased expression of ACADL protein

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164

G

aggrecan

increases expression

ISO

Glyphosate results in increased expression of ACAN mRNA

NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779

G

angiotensin converting enzyme 2

affects methylation

EXP

Glyphosate affects the methylation of ACE2 gene

NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596

G

acetylcholinesterase

increases expression
decreases activity

ISO
EXP

Glyphosate results in increased expression of ACHE mRNA
Glyphosate results in decreased activity of ACHE protein

PMID:28627408 PMID:30682438 PMID:32067069 PMID:35897073

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

ATP citrate lyase

decreases expression

ISO

Glyphosate results in decreased expression of ACLY protein

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

acyl-CoA thioesterase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ACOT2 gene

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502

G

acyl-CoA thioesterase 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACOT4 mRNA

NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138

G

acrosin

increases methylation

EXP

Glyphosate results in increased methylation of ACR gene

NCBI chr 7:122,517,910...122,524,110
Ensembl chr 7:122,517,934...122,524,087

G

acyl-CoA synthetase bubblegum family member 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ACSBG1 mRNA

NCBI chr 8:63,887,433...63,943,486
Ensembl chr 8:63,887,435...63,984,178

G

acyl-CoA synthetase family member 2

decreases expression

ISO

Glyphosate results in decreased expression of ACSF2 protein

NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050

G

acyl-CoA synthetase long-chain family member 1

decreases expression

ISO

Glyphosate results in decreased expression of ACSL1 protein

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023

G

acyl-CoA synthetase long-chain family member 5

decreases expression

ISO

Glyphosate results in decreased expression of ACSL5 protein

NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943

G

acyl-CoA synthetase medium-chain family member 3

decreases expression

EXP

Glyphosate results in decreased expression of ACSM3 mRNA

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437

G

actin, beta

decreases expression
affects methylation

ISO
EXP

Glyphosate results in decreased expression of ACTB mRNA
Glyphosate affects the methylation of RASA4 gene

PMID:31295307 PMID:35440735

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242

G

actin gamma 2, smooth muscle

affects expression

ISO

Glyphosate affects the expression of ACTG2 protein

NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295

G

actin related protein 3B

increases methylation

EXP

Glyphosate results in increased methylation of ACTR3B gene

NCBI chr 4:9,995,553...10,089,422
Ensembl chr 4:9,996,155...10,089,553

G

actin-related protein T3

decreases expression

EXP

Glyphosate results in decreased expression of ACTRT3 mRNA

NCBI chr 2:114,727,534...114,729,561
Ensembl chr 2:114,727,534...114,729,563

G

activin A receptor type 1

increases expression
affects methylation

ISO
EXP

Glyphosate results in increased expression of ACVR1 mRNA
Glyphosate affects the methylation of ACVR1 gene

PMID:31295307 PMID:35440735

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884

G

activin A receptor type 2B

increases expression
decreases expression

ISO

Glyphosate results in increased expression of ACVR2B mRNA
Glyphosate results in decreased expression of ACVR2B mRNA

NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:128,016,526...128,048,171

G

aminoacylase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACY1 mRNA

NCBI chr 8:115,951,068...115,956,471
Ensembl chr 8:115,951,068...115,956,405

G

ADAM metallopeptidase domain 15

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAM15 gene

NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849

G

ADAM metallopeptidase domain 17

decreases expression

ISO

Glyphosate results in decreased expression of ADAM17 mRNA

NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344

G

ADAM metallopeptidase domain 19

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ADAM19 mRNA

NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455

G

ADAM metallopeptidase domain 23

affects methylation

EXP

Glyphosate affects the methylation of ADAM23 gene

NCBI chr 9:72,356,479...72,503,545
Ensembl chr 9:72,356,479...72,503,545

G

ADAM metallopeptidase domain 32

affects methylation

EXP

Glyphosate affects the methylation of ADAM32 gene

NCBI chr16:73,805,023...73,914,787
Ensembl chr16:73,805,052...73,914,785

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

affects methylation

EXP

Glyphosate affects the methylation of ADAMTS1 gene

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390

G

ADAM metallopeptidase with thrombospondin type 1 motif, 19

increases methylation

EXP

Glyphosate results in increased methylation of ADAMTS19 gene

NCBI chr18:54,545,357...54,729,184
Ensembl chr18:54,545,357...54,729,181

G

ADAMTS-like 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAMTSL3 gene

NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:145,698,004...146,006,195

G

ADAMTS-like 4

increases expression

ISO

Glyphosate results in increased expression of ADAMTSL4 mRNA

NCBI chr 2:185,924,582...185,936,039
Ensembl chr 2:185,924,594...185,935,796

G

ADAMTS-like 5

decreases expression

EXP

Glyphosate results in decreased expression of ADAMTSL5 mRNA

NCBI chr 7:10,013,306...10,021,924
Ensembl chr 7:10,013,929...10,021,924

G

adenosine deaminase, RNA-specific, B1

increases methylation

EXP

Glyphosate results in increased methylation of ADARB1 gene

NCBI chr20:11,222,171...11,350,416
Ensembl chr20:11,222,164...11,350,415

G

adenylate cyclase 10

increases expression

EXP

Glyphosate results in increased expression of ADCY10 mRNA

NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926

G

adenylate cyclase 6

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ADCY6 mRNA

NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770

G

adducin 1

increases methylation

EXP

Glyphosate results in increased methylation of ADD1 gene

NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732

G

adducin 3

increases methylation

EXP

Glyphosate results in increased methylation of ADD3 gene

NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504

G

adhesion G protein-coupled receptor B2

affects methylation

EXP

Glyphosate affects the methylation of ADGRB2 gene

NCBI chr 5:147,581,573...147,646,726
Ensembl chr 5:147,611,580...147,646,726

G

adhesion G protein-coupled receptor L3

affects methylation

EXP

Glyphosate affects the methylation of ADGRL3 gene

NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418

G

adhesion G protein-coupled receptor V1

decreases methylation

EXP

Glyphosate results in decreased methylation of ADGRV1 gene

NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372

G

acireductone dioxygenase 1

increases expression

ISO

Glyphosate results in increased expression of ADI1 protein

NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855

G

adiponectin receptor 2

increases expression

ISO

Glyphosate results in increased expression of ADIPOR2 mRNA

NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:154,172,567...154,231,666

G

ADRM1 26S proteasome ubiquitin receptor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ADRM1 mRNA

NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483

G

AE binding protein 2

affects methylation

EXP

Glyphosate affects the methylation of AEBP2 gene

NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422

G

AFG1 like ATPase

affects methylation

EXP

Glyphosate affects the methylation of AFG1L gene

NCBI chr20:47,380,582...47,550,307
Ensembl chr20:47,380,583...47,550,126

G

alpha-fetoprotein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AFP mRNA

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

affects methylation

EXP

Glyphosate affects the methylation of AGAP1 gene

NCBI chr 9:97,487,382...97,922,870
Ensembl chr 9:97,487,406...97,922,870

G

anterior gradient 2, protein disulphide isomerase family member

decreases expression

ISO

Glyphosate results in decreased expression of AGR2 mRNA

NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677

G

agrin

affects methylation

EXP

Glyphosate affects the methylation of AGRN gene

NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539

G

angiotensinogen

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AGT mRNA

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

AHNAK nucleoprotein 2

increases expression

ISO

Glyphosate results in increased expression of AHNAK2 mRNA

NCBI chr 6:137,648,867...137,697,580
Ensembl chr 6:137,652,537...137,675,546

G

aryl hydrocarbon receptor

affects expression

ISO

Glyphosate affects the expression of AHR mRNA

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

allograft inflammatory factor 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA

NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339

G

apoptosis inducing factor, mitochondria associated 1

decreases expression

ISO

Glyphosate results in decreased expression of AIFM1 mRNA

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237

G

androgen-induced 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of AIG1 gene

NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155

G

adenylate kinase 3

increases expression

ISO

Glyphosate results in increased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183

G

adenylate kinase 9

decreases expression

EXP

Glyphosate results in decreased expression of AK9 mRNA

NCBI chr20:46,307,100...46,523,537
Ensembl chr20:46,307,119...46,523,536

G

A-kinase anchoring protein 8

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8 mRNA

NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900

G

A-kinase anchoring protein 8 like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8L mRNA

NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811

G

aldo-keto reductase family 1 member B1

decreases expression

EXP

Glyphosate results in decreased expression of AKR1B1 mRNA

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1, member C1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of AKR1C6 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

aldo-keto reductase family 1, member C3

decreases expression

ISO

Glyphosate results in decreased expression of AKR1C18 protein

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

AKT serine/threonine kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of AKT1 mRNA

PMID:31295307 PMID:31874349

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

albumin

increases expression
decreases expression
affects binding
affects expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of ALB mRNA; Glyphosate results in increased expression of ALB protein
Glyphosate results in decreased expression of ALB mRNA
Glyphosate binds to ALB protein
Glyphosate affects the expression of ALB protein
Zinc inhibits the reaction [Glyphosate results in increased expression of ALB protein]

PMID:18035550 PMID:20045496 PMID:25067936 PMID:26302742 PMID:38314887

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 16 family, member A1

decreases expression

ISO

Glyphosate results in decreased expression of ALDH16A1 protein

NCBI chr 1:104,763,200...104,776,270
Ensembl chr 1:104,763,055...104,776,270

G

aldehyde dehydrogenase 1 family, member A3

decreases expression

ISO

Glyphosate results in decreased expression of ALDH1A3 mRNA

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

ISO

Glyphosate results in decreased expression of ALDH4A1 protein

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673

G

aldehyde dehydrogenase 7 family, member A1

increases expression

ISO

Glyphosate results in increased expression of ALDH7A1 protein

NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467

G

aldehyde dehydrogenase 8 family, member A1

affects methylation

EXP

Glyphosate affects the methylation of ALDH8A1 gene

NCBI chr 1:18,003,507...18,022,952
Ensembl chr 1:18,003,514...18,023,883

G

aldehyde dehydrogenase 9 family, member A1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALDH9A1 mRNA

NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481

G

aldolase 1 A retrogene 2

increases methylation

EXP

Glyphosate results in increased methylation of ALDOART2 gene

NCBI chr 6:78,674,945...78,676,635
Ensembl chr 6:78,673,353...78,680,406

G

ALG2, alpha-1,3/1,6-mannosyltransferase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALG2 mRNA

NCBI chr 5:66,564,328...66,568,887
Ensembl chr 5:66,564,330...66,568,887

G

ALG5, dolichyl-phosphate beta-glucosyltransferase

decreases expression

EXP

Glyphosate results in decreased expression of ALG5 mRNA

NCBI chr 2:141,087,126...141,101,397
Ensembl chr 2:141,087,147...141,102,951

G

ALG9, alpha-1,2-mannosyltransferase

increases expression

ISO

Glyphosate results in increased expression of ALG9 mRNA

NCBI chr 8:60,013,429...60,085,159
Ensembl chr 8:60,009,618...60,085,054

G

angiomotin-like 1

increases methylation

EXP

Glyphosate results in increased methylation of AMOTL1 gene

NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869

G

adenosine monophosphate deaminase 3

increases expression

ISO

Glyphosate results in increased expression of AMPD3 mRNA

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608

G

amphiphysin

affects methylation

EXP

Glyphosate affects the methylation of AMPH gene

NCBI chr17:50,435,018...50,678,583
Ensembl chr17:50,435,018...50,678,501

G

anaphase promoting complex subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of ANAPC1 mRNA

NCBI chr 3:136,303,350...136,383,464
Ensembl chr 3:136,303,413...136,383,464

G

anaphase promoting complex subunit 13

decreases expression

ISO

Glyphosate results in decreased expression of ANAPC13 mRNA

NCBI chr 8:112,084,405...112,092,821
Ensembl chr 8:112,084,405...112,092,821

G

anaphase promoting complex subunit 4

decreases methylation

EXP

Glyphosate results in decreased methylation of ANAPC4 gene

NCBI chr14:62,338,798...62,370,572
Ensembl chr14:62,338,798...62,370,572

G

anaphase-promoting complex subunit 5

decreases methylation
decreases expression

EXP
ISO

Glyphosate results in decreased methylation of ANAPC5 gene
Glyphosate results in decreased expression of ANAPC5 mRNA

PMID:31011160 PMID:31295307

NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762

G

angiopoietin 1

decreases expression
increases expression
decreases methylation

ISO
EXP

Glyphosate results in decreased expression of ANGPT1 mRNA
Glyphosate results in increased expression of ANGPT1 mRNA
Glyphosate results in decreased methylation of ANGPT1 gene

PMID:31011160 PMID:31295307

NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696

G

angiopoietin 2

affects expression

EXP

Glyphosate affects the expression of ANGPT2 mRNA

NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239

G

angiopoietin 4

decreases expression

ISO

Glyphosate results in decreased expression of ANGPT4 protein

NCBI chr 3:160,880,539...160,913,923
Ensembl chr 3:160,880,728...160,913,921

G

angiopoietin-like 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681

G

ankyrin repeat domain 13a

increases expression
increases methylation

ISO
EXP

Glyphosate results in increased expression of ANKRD13A mRNA
Glyphosate results in increased methylation of ANKRD13A gene

PMID:31011160 PMID:35897073

NCBI chr12:47,458,828...47,488,959
Ensembl chr12:47,458,831...47,489,312

G

ankyrin repeat domain 17

increases expression

EXP

Glyphosate results in increased expression of ANKRD17 mRNA

NCBI chr14:18,007,342...18,145,980
Ensembl chr14:18,008,859...18,145,980

G

ankyrin repeat domain 28

affects methylation

EXP

Glyphosate affects the methylation of ANKRD28 gene

NCBI chr16:6,924,868...7,056,593
Ensembl chr16:6,924,882...7,056,593

G

ankyrin repeat domain 48

increases expression

EXP

Glyphosate results in increased expression of ANKRD36 mRNA

NCBI chr14:84,665,671...84,782,434
Ensembl chr14:84,665,694...84,782,434

G

ankyrin repeat and sterile alpha motif domain containing 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ANKS3 mRNA

NCBI chr10:11,121,504...11,142,261
Ensembl chr10:11,121,553...11,142,491

G

anillin, actin binding protein

increases expression

ISO

Glyphosate results in increased expression of ANLN mRNA

NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513

G

anoctamin 2

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of ANO2 gene
Glyphosate results in increased expression of ANO2 mRNA

PMID:35440735 PMID:35489704

NCBI chr 4:160,200,471...160,541,830
Ensembl chr 4:160,182,152...160,541,821

G

acidic nuclear phosphoprotein 32 family member A

increases expression

ISO

Glyphosate results in increased expression of ANP32A protein

NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922

G

annexin A1

increases expression
affects methylation

ISO
EXP

Glyphosate results in increased expression of ANXA1 mRNA
Glyphosate affects the methylation of ANXA1 gene

PMID:35440735 PMID:37047296

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A10

affects methylation

EXP

Glyphosate affects the methylation of ANXA10 gene

NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961

G

annexin A11

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANXA11 mRNA

NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839

G

annexin A2

increases expression

ISO

Glyphosate results in increased expression of ANXA2 protein

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A4

increases methylation

EXP

Glyphosate results in increased methylation of ANXA4 gene

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513

G

aminopeptidase O

decreases methylation

EXP

Glyphosate results in decreased methylation of AOPEP gene

NCBI chr17:1,817,001...2,133,008
Ensembl chr17:1,817,001...2,133,104

G

aldehyde oxidase 2

increases expression

EXP

Glyphosate results in increased expression of AOX2 mRNA

NCBI chr 9:67,322,291...67,411,694
Ensembl chr 9:67,322,598...67,410,363

G

aldehyde oxidase 3

decreases expression

EXP

Glyphosate results in decreased expression of AOX3 mRNA

NCBI chr 9:67,158,987...67,245,299
Ensembl chr 9:67,159,000...67,244,013

G

adaptor related protein complex 3 subunit beta 1

affects methylation

EXP

Glyphosate affects the methylation of AP3B1 gene

NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:27,334,900...27,537,702

G

adaptor related protein complex 4 subunit epsilon 1

increases methylation

EXP

Glyphosate results in increased methylation of AP4E1 gene

NCBI chr 3:134,726,338...134,792,820
Ensembl chr 3:134,726,287...134,792,818

G

apoptotic peptidase activating factor 1

affects methylation
increases expression
decreases expression

EXP
ISO

Glyphosate affects the methylation of APAF1 gene
Glyphosate results in increased expression of APAF1 mRNA
Glyphosate results in decreased expression of APAF1 mRNA; Glyphosate results in decreased expression of APAF1 protein

PMID:24073338 PMID:31295307 PMID:31874349 PMID:35440735

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772

G

amyloid beta precursor protein binding family A member 2

affects methylation

EXP

Glyphosate affects the methylation of APBA2 gene

NCBI chr 1:127,465,026...127,698,124
Ensembl chr 1:127,465,009...127,698,117

G

apurinic/apyrimidinic endodeoxyribonuclease 2

decreases expression

ISO

Glyphosate results in decreased expression of APEX2 mRNA

NCBI chr X:22,914,943...22,937,713
Ensembl chr X:22,914,944...22,936,011

G

APAF1 interacting protein

decreases expression
affects methylation

EXP

Glyphosate results in decreased expression of APIP mRNA
Glyphosate affects the methylation of APIP gene

PMID:26302742 PMID:35440735

NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:109,886,953...109,915,862

G

aprataxin and PNKP like factor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APLF mRNA

NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961

G

apolipoprotein A2

decreases expression

ISO

Glyphosate results in decreased expression of APOA2 protein

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410

G

apolipoprotein B receptor

increases expression

EXP

Glyphosate results in increased expression of APOBR mRNA

NCBI chr 1:190,599,595...190,603,782
Ensembl chr 1:190,597,638...190,616,809

G

apolipoprotein E

decreases expression

ISO

Glyphosate results in decreased expression of APOE protein

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

apolipoprotein F

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APOF mRNA

NCBI chr 7:1,285,222...1,286,659
Ensembl chr 7:1,285,222...1,286,659

G

apolipoprotein L9a

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of APOL9A mRNA

NCBI chr 7:111,021,452...111,030,380
Ensembl chr 7:111,021,453...111,028,213

G

apolipoprotein O

increases methylation

EXP

Glyphosate results in increased methylation of APOO gene

NCBI chr X:63,151,736...63,256,696
Ensembl chr X:63,151,814...63,256,690

G

amyloid beta precursor protein

increases expression

ISO

Glyphosate results in increased expression of APP mRNA

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

aprataxin

affects methylation

EXP

Glyphosate affects the methylation of APTX gene

NCBI chr 5:60,593,338...60,618,946
Ensembl chr 5:60,597,648...60,618,790

G

androgen receptor

affects expression
multiple interactions
decreases expression
decreases activity
increases expression

ISO
EXP

Glyphosate affects the expression of AR mRNA
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of AR protein
Glyphosate results in decreased expression of AR mRNA
Glyphosate results in decreased activity of AR protein
Glyphosate results in increased expression of AR protein
[Glyphosate co-treated with Herbicides] results in decreased activity of AR protein

PMID:19539684 PMID:30447247 PMID:35457321 PMID:37615203

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

ARB2 cotranscriptional regulator A

affects methylation

EXP

Glyphosate affects the methylation of ARB2A gene

NCBI chr 2:9,289,694...9,753,991
Ensembl chr 2:9,289,699...9,753,989

G

ADP-ribosylation factor 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ARF2 mRNA

NCBI chr10:89,367,843...89,389,644
Ensembl chr10:89,368,044...89,389,651

G

ARF GTPase 3

decreases expression

ISO

Glyphosate results in decreased expression of ARF3 protein

NCBI chr 7:131,765,039...131,792,075
Ensembl chr 7:131,750,672...131,770,123

G

ARF GTPase 4

increases expression

ISO

Glyphosate results in increased expression of ARF4 mRNA

NCBI chr16:1,903,238...1,920,012
Ensembl chr16:1,903,371...1,920,011

G

ARF GTPase 6

increases expression

ISO

Glyphosate results in increased expression of ARF6 mRNA

NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:93,569,234...93,610,536

G

ARF GTPase activating protein 1

increases expression

EXP

Glyphosate results in increased expression of ARFGAP1 mRNA

NCBI chr 3:188,462,125...188,477,515
Ensembl chr 3:188,465,648...188,511,078

G

ARF guanine nucleotide exchange factor 1

affects methylation

EXP

Glyphosate affects the methylation of ARFGEF1 gene

NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:13,764,975...13,859,237

G

Rho GTPase activating protein 15

decreases expression

ISO

Glyphosate results in decreased expression of ARHGAP15 mRNA

NCBI chr 3:48,382,945...49,002,213
Ensembl chr 3:48,382,904...49,011,378

G

Rho GTPase activating protein 22

decreases methylation
affects methylation

EXP

Glyphosate results in decreased methylation of ARHGAP22 gene
Glyphosate affects the methylation of ARHGAP22 gene

PMID:31011160 PMID:35440735

NCBI chr16:8,480,222...8,637,823
Ensembl chr16:8,479,956...8,637,822

G

Rho GTPase activating protein 24

affects methylation

EXP

Glyphosate affects the methylation of ARHGAP24 gene

NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950

G

Rho GTPase activating protein 29

decreases expression

ISO

Glyphosate results in decreased expression of ARHGAP29 protein

NCBI chr 2:212,744,626...212,816,710
Ensembl chr 2:212,755,803...212,986,729

G

Rho GTPase activating protein 31

increases methylation

EXP

Glyphosate results in increased methylation of ARHGAP31 gene

NCBI chr11:75,544,176...75,657,087
Ensembl chr11:75,544,040...75,661,076

G

Rho GTPase activating protein 6

decreases expression

EXP

Glyphosate results in decreased expression of ARHGAP6 mRNA

NCBI chr X:28,525,912...29,062,344
Ensembl chr X:28,525,917...29,061,244

G

Rho GTPase activating protein 9

decreases expression

EXP

Glyphosate results in decreased expression of ARHGAP9 mRNA

NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336

G

Rho GDP dissociation inhibitor alpha

decreases expression

ISO

Glyphosate results in decreased expression of ARHGDIA protein

NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347

G

Rho guanine nucleotide exchange factor 10

increases expression

ISO

Glyphosate results in increased expression of ARHGEF10 mRNA

NCBI chr16:81,349,429...81,440,439
Ensembl chr16:81,349,429...81,440,054

G

Rho guanine nucleotide exchange factor 10 like

affects methylation

EXP

Glyphosate affects the methylation of ARHGEF10L gene

NCBI chr 5:158,075,370...158,218,358
Ensembl chr 5:158,075,370...158,180,685

G

Rho guanine nucleotide exchange factor 12

decreases methylation

EXP

Glyphosate results in decreased methylation of ARHGEF12 gene

NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376

G

Rho/Rac guanine nucleotide exchange factor 18

decreases methylation

EXP

Glyphosate results in decreased methylation of ARHGEF18 gene

NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997

G

Rho guanine nucleotide exchange factor 4

affects methylation

EXP

Glyphosate affects the methylation of ARHGEF4 gene

NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550

G

AT-rich interaction domain 1B

affects methylation

EXP

Glyphosate affects the methylation of ARID1B gene

NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793

G

AT-rich interaction domain 4B

increases expression

EXP

Glyphosate results in increased expression of ARID4B mRNA

NCBI chr17:55,833,908...55,958,382
Ensembl chr17:55,833,908...55,958,382

G

AT-rich interaction domain 5B

increases expression

ISO

Glyphosate results in increased expression of ARID5B mRNA

NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686

G

ARF like GTPase 5C

multiple interactions
increases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ARL5C mRNA
Glyphosate results in increased expression of ARL5C mRNA

PMID:37567420 PMID:38314887

NCBI chr10:83,481,540...83,492,915
Ensembl chr10:83,481,540...83,488,406

G

ARL6 interacting reticulophagy regulator 1

decreases expression

EXP

Glyphosate results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232

G

armadillo repeat containing 3

decreases expression

EXP

Glyphosate results in decreased expression of ARMC3 mRNA

NCBI chr17:86,722,436...86,825,899
Ensembl chr17:86,722,441...86,825,899

G

armadillo repeat containing 9

increases methylation

EXP

Glyphosate results in increased methylation of ARMC9 gene

NCBI chr 9:94,250,492...94,376,589
Ensembl chr 9:94,250,859...94,376,589

G

actin related protein 2/3 complex, subunit 1A

multiple interactions
increases methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ARPC1A gene
Glyphosate results in increased methylation of ARPC1A gene

PMID:31011160 PMID:33854195

NCBI chr12:14,616,245...14,639,052
Ensembl chr12:14,616,248...14,639,052

G

actin related protein 2/3 complex, subunit 4

increases expression

ISO

Glyphosate results in increased expression of ARPC4 protein

PMID:36173347 PMID:37208198

NCBI chr 4:148,077,799...148,088,427
Ensembl chr 4:148,077,240...148,088,428

G

arrestin, beta 1

decreases expression

ISO

Glyphosate results in decreased expression of ARRB1 mRNA

NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859

G

arrestin domain containing 2

increases expression

ISO

Glyphosate results in increased expression of ARRDC2 mRNA

NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158

G

arrestin domain containing 3

increases expression

ISO

Glyphosate results in increased expression of ARRDC3 mRNA

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875

G

arylsulfatase family, member J

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of ARSJ mRNA

NCBI chr 2:217,449,147...217,529,142
Ensembl chr 2:217,449,147...217,529,142

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

increases methylation

EXP

Glyphosate results in increased methylation of ASAP2 gene

NCBI chr 6:46,386,605...46,549,669
Ensembl chr 6:46,386,605...46,549,669

G

ankyrin repeat and SOCS box-containing 10

increases methylation

EXP

Glyphosate results in increased methylation of ASB10 gene

NCBI chr 4:11,522,531...11,531,946
Ensembl chr 4:11,522,887...11,531,505

G

ankyrin repeat and SOCS box-containing 7

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ASB7 mRNA

NCBI chr 1:129,621,462...129,677,788
Ensembl chr 1:129,635,330...129,677,505

G

ankyrin repeat and SOCS box-containing 8

affects methylation

EXP

Glyphosate affects the methylation of ASB8 gene

NCBI chr 7:131,140,455...131,176,648
Ensembl chr 7:131,141,406...131,150,633

G

achaete-scute family bHLH transcription factor 3

decreases expression

EXP

Glyphosate results in decreased expression of ASCL3 mRNA

NCBI chr 1:173,190,061...173,194,302
Ensembl chr 1:173,190,228...173,192,197

G

ASH1 like histone lysine methyltransferase

decreases expression

EXP

Glyphosate results in decreased expression of ASH1L mRNA

NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847

G

acid sensing ion channel subunit 2

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of ASIC2 gene
Glyphosate affects the methylation of ASIC2 gene

PMID:31011160 PMID:35440735

NCBI chr10:66,368,308...67,438,237
Ensembl chr10:66,368,310...66,636,245

G

acid sensing ion channel subunit family member 4

decreases expression

EXP

Glyphosate results in decreased expression of ASIC4 mRNA

NCBI chr 9:84,389,610...84,411,545
Ensembl chr 9:84,390,104...84,411,538

G

acetylserotonin O-methyltransferase

increases expression

EXP

Glyphosate results in increased expression of ASMT mRNA

NCBI chr12:21,418,477...21,423,336
Ensembl chr12:21,418,487...21,423,336

G

aspartoacylase

affects methylation

EXP

Glyphosate affects the methylation of ASPA gene

NCBI chr10:58,390,204...58,443,790
Ensembl chr10:58,379,410...58,443,769

G

argininosuccinate synthase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ASS1 mRNA

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627

G

astrotactin 1

increases expression

EXP

Glyphosate results in increased expression of ASTN1 mRNA

NCBI chr13:73,070,754...73,388,902
Ensembl chr13:73,071,267...73,388,895

G

ASXL transcriptional regulator 3

affects methylation

EXP

Glyphosate affects the methylation of ASXL3 gene

NCBI chr18:13,868,223...14,040,867
Ensembl chr18:13,868,674...14,037,373

G

activating transcription factor 4

increases expression

ISO

Glyphosate results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

autophagy related 12

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of ATG12 mRNA
Melatonin inhibits the reaction [Glyphosate results in increased expression of ATG12 protein]

PMID:31352102 PMID:31874349 PMID:33159990

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261

G

autophagy related 14

increases expression

ISO

Glyphosate results in increased expression of ATG14 mRNA

NCBI chr15:23,275,457...23,306,817
Ensembl chr15:23,275,457...23,306,815

G

autophagy related 3

increases expression

ISO

Glyphosate results in increased expression of ATG3 mRNA

NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280

G

autophagy related 5

increases expression

ISO

Glyphosate results in increased expression of ATG5 mRNA

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821

G

atlastin GTPase 3

decreases expression

ISO

Glyphosate results in decreased expression of ATL3 protein

NCBI chr 1:214,110,127...214,151,098
Ensembl chr 1:214,109,702...214,152,510

G

atos homolog A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA

NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091

G

antioxidant 1 copper chaperone

increases expression

ISO

Glyphosate results in increased expression of ATOX1 protein

NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585

G

ATPase phospholipid transporting 10B

affects methylation

EXP

Glyphosate affects the methylation of ATP10B gene

NCBI chr10:27,996,729...28,252,801
Ensembl chr10:27,910,295...28,251,450

G

ATPase phospholipid transporting 11A

increases expression

ISO

Glyphosate results in increased expression of ATP11A mRNA

NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

increases expression

EXP

Glyphosate results in increased expression of ATP12A mRNA

NCBI chr15:34,559,209...34,583,866
Ensembl chr15:34,559,209...34,583,866

G

ATPase 13A1

increases expression

EXP

Glyphosate results in increased expression of ATP13A1 mRNA

NCBI chr16:19,649,065...19,665,126
Ensembl chr16:19,649,066...19,665,120

G

ATPase 13A4

decreases expression

ISO

Glyphosate results in decreased expression of ATP13A4 mRNA

NCBI chr11:84,727,014...84,864,747
Ensembl chr11:84,731,041...84,864,747

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

affects methylation

EXP

Glyphosate affects the methylation of ATP2A2 gene

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934

G

ATP synthase F1 subunit beta

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of ATP5F1B mRNA
Glyphosate results in increased expression of ATP5F1B mRNA

PMID:26302742 PMID:36608876

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462

G

ATP synthase F1 subunit delta

decreases expression

EXP
ISO

Glyphosate results in decreased expression of ATP5F1D mRNA
Glyphosate results in decreased expression of ATP5D mRNA

PMID:26302742 PMID:37657410

NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583

G

ATP synthase membrane subunit c locus 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP5MC1 mRNA

NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363

G

ATPase H+ transporting V0 subunit a2

decreases expression

ISO

Glyphosate results in decreased expression of ATP6V0A2 mRNA

NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860

G

ATPase H+ transporting V0 subunit D1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP6V0D1 mRNA

NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395

G

ATPase H+ transporting V1 subunit C2

decreases expression

EXP

Glyphosate results in decreased expression of ATP6V1C2 mRNA

NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747

G

ATPase phospholipid transporting 8B4 (putative)

decreases methylation

EXP

Glyphosate results in decreased methylation of ATP8B4 gene

NCBI chr 3:134,008,367...134,212,394
Ensembl chr 3:134,009,580...134,210,260

G

ATPase phospholipid transporting 9A (putative)

increases expression

ISO

Glyphosate results in increased expression of ATP9A mRNA

NCBI chr 3:177,779,203...177,886,431
Ensembl chr 3:177,779,203...178,023,661

G

ataxin 1

increases expression

EXP

Glyphosate results in increased expression of ATXN1 mRNA

NCBI chr17:18,943,397...19,354,751
Ensembl chr17:19,208,200...19,356,790

G

AU RNA binding methylglutaconyl-CoA hydratase

decreases expression

ISO

Glyphosate results in decreased expression of AUH protein

NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587

G

arginine vasopressin receptor 1A

decreases expression

EXP

Glyphosate results in decreased expression of AVPR1A mRNA

NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837

G

axin 2

increases methylation

EXP

Glyphosate results in increased methylation of AXIN2 gene

NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575

G

Axl receptor tyrosine kinase

affects methylation

EXP

Glyphosate affects the methylation of AXL gene

NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009

G

beta-2 microglobulin

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

Beta-1,3-galactosyltransferase 1

affects methylation

EXP

Glyphosate affects the methylation of B3GALT1 gene

NCBI chr 3:72,661,410...73,234,447
Ensembl chr 3:72,660,801...73,235,276

G

Beta-1,3-galactosyltransferase 5

increases expression

ISO

Glyphosate results in increased expression of B3GALT5 mRNA

NCBI chr11:49,053,959...49,100,398
Ensembl chr11:49,006,560...49,101,283

G

beta-1,3-glucuronyltransferase 2

decreases methylation

EXP

Glyphosate results in decreased methylation of B3GAT2 gene

NCBI chr 9:33,663,482...33,746,466
Ensembl chr 9:33,663,482...33,746,466

G

beta 3-glucosyltransferase

increases methylation

EXP

Glyphosate results in increased methylation of B3GLCT gene

NCBI chr12:10,291,910...10,383,190
Ensembl chr12:10,291,910...10,426,357

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

affects methylation

ISO

Glyphosate affects the methylation of B3GNT2 gene

NCBI chr14:101,009,682...101,034,507
Ensembl chr14:100,967,131...101,043,412

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1

affects methylation

EXP

Glyphosate affects the methylation of B3GNTL1 gene

NCBI chr10:107,363,036...107,431,988
Ensembl chr10:107,371,442...107,431,908

G

beta-1,4-galactosyltransferase 2

increases methylation

EXP

Glyphosate results in increased methylation of B4GALT2 gene

NCBI chr 5:136,697,981...136,707,783
Ensembl chr 5:136,697,981...136,710,422

G

beta-1,4-galactosyltransferase 6

decreases methylation

EXP

Glyphosate results in decreased methylation of B4GALT6 gene

NCBI chr18:12,233,350...12,290,204
Ensembl chr18:12,233,351...12,290,204

G

BCL2-associated agonist of cell death

increases expression

ISO

Glyphosate results in increased expression of BAD protein

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BAG cochaperone 3

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BAG3 mRNA
Glyphosate results in increased expression of BAG3 mRNA

PMID:33854195 PMID:35897073

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

ISO

Glyphosate results in increased expression of BAIAP2L1 mRNA

NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605

G

BAI1-associated protein 3

decreases expression

EXP

Glyphosate results in decreased expression of BAIAP3 mRNA

NCBI chr10:14,764,768...14,777,516
Ensembl chr10:14,756,693...14,777,516

G

BMP and activin membrane-bound inhibitor

decreases expression

ISO

Glyphosate results in decreased expression of BAMBI mRNA

NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247

G

Btg3 associated nuclear protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BANP mRNA

NCBI chr19:66,916,417...66,994,286
Ensembl chr19:66,916,267...66,991,317

G

brain abundant, membrane attached signal protein 1

decreases methylation

EXP

Glyphosate results in decreased methylation of BASP1 gene

NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178

G

basic leucine zipper ATF-like transcription factor 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BATF2 mRNA

NCBI chr 1:212,897,076...212,905,740
Ensembl chr 1:212,875,148...212,905,831

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression
decreases expression

ISO
EXP

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX protein
[Surface-Active Agents co-treated with Glyphosate] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of BAX mRNA]
Glyphosate results in increased expression of BAX mRNA; Glyphosate results in increased expression of BAX protein
Melatonin inhibits the reaction [Glyphosate results in increased expression of BAX mRNA]; XAF1 protein affects the reaction [Glyphosate results in increased expression of BAX protein]
Glyphosate results in decreased expression of BAX protein

PMID:23099315 PMID:24073338 PMID:29908847 PMID:30785197 PMID:30907447 More...

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

bromodomain adjacent to zinc finger domain, 2A

increases expression

EXP

Glyphosate results in increased expression of BAZ2A mRNA

NCBI chr 7:1,107,377...1,145,507
Ensembl chr 7:1,107,796...1,145,507

G

Bcl-2 binding component 3

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BBC3 mRNA

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666

G

butyrylcholinesterase

multiple interactions
decreases activity

ISO

CYP1A1 gene SNP promotes the reaction [Glyphosate results in decreased activity of BCHE protein]

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

branched chain keto acid dehydrogenase E1 subunit beta

affects methylation

EXP

Glyphosate affects the methylation of BCKDHB gene

NCBI chr 8:93,725,277...93,907,799
Ensembl chr 8:93,725,275...93,907,798

G

BCL10, immune signaling adaptor

decreases expression

EXP

Glyphosate results in decreased expression of BCL10 mRNA

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829

G

BCL11 transcription factor A

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of BCL11A mRNA

NCBI chr14:102,230,147...102,325,289
Ensembl chr14:102,231,113...102,325,623

G

BCL2, apoptosis regulator

multiple interactions
increases expression
decreases expression

EXP
ISO

[Surface-Active Agents co-treated with Glyphosate] results in decreased expression of BCL2 protein
Melatonin inhibits the reaction [Glyphosate results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [Glyphosate results in decreased expression of BCL2 protein]
Glyphosate results in increased expression of BCL2 mRNA
Glyphosate results in decreased expression of BCL2 mRNA; Glyphosate results in decreased expression of BCL2 protein
Glyphosate results in increased expression of BCL2 mRNA; Glyphosate results in increased expression of BCL2 protein
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein

PMID:23099315 PMID:24073338 PMID:29908847 PMID:30785197 PMID:30907447 More...

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

BCL2-related protein A1

increases expression

ISO

Glyphosate results in increased expression of BCL2A1 mRNA

NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890

G

Bcl2-like 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of BCL2L1 protein
Glyphosate results in increased expression of BCL2L1 mRNA

PMID:17984146 PMID:30907447 PMID:35897073

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 15

decreases expression

EXP

Glyphosate results in decreased expression of BCL2L15 mRNA

NCBI chr 2:194,019,158...194,032,516
Ensembl chr 2:194,027,397...194,032,516

G

BCL9, transcription coactivator

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of BCL9 mRNA

NCBI chr 2:187,449,425...187,475,241
Ensembl chr 2:187,449,425...187,475,241

G

brain-derived neurotrophic factor

decreases expression

ISO

Glyphosate results in decreased expression of BDNF mRNA

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

beclin 1

increases expression
increases response to substance

EXP
ISO

Glyphosate results in increased expression of BECN1 mRNA
BECN1 results in increased susceptibility to Glyphosate

PMID:22504123 PMID:26302742 PMID:33159990

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002

G

basic helix-loop-helix family, member a15

increases expression

EXP

Glyphosate results in increased expression of BHLHA15 mRNA

NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515

G

betaine-homocysteine S-methyltransferase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BHMT mRNA

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715

G

BH3 interacting domain death agonist

decreases expression

ISO

Glyphosate results in decreased expression of BID mRNA

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275

G

baculoviral IAP repeat-containing 2

increases expression
decreases expression
multiple interactions

ISO

Glyphosate results in increased expression of BIRC2 mRNA
Glyphosate results in decreased expression of BIRC2 mRNA
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BIRC2 mRNA

PMID:31295307 PMID:31874349 PMID:32800223

NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911

G

baculoviral IAP repeat-containing 7

increases expression

EXP

Glyphosate results in increased expression of BIRC7 mRNA

NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:188,425,392...188,430,174

G

bridge-like lipid transfer protein family member 3B

increases methylation

EXP

Glyphosate results in increased methylation of BLTP3B gene

NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083

G

basic leucine zipper nuclear factor 1

increases methylation

EXP

Glyphosate results in increased methylation of BLZF1 gene

NCBI chr13:79,174,898...79,190,116
Ensembl chr13:79,174,902...79,190,116

G

basic helix-loop-helix ARNT like 1

decreases expression

ISO

Glyphosate results in decreased expression of BMAL1 mRNA

NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739

G

bone morphogenetic protein 2

decreases expression

EXP

Glyphosate results in decreased expression of BMP2 mRNA

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760

G

bone morphogenetic protein 3

affects methylation

EXP

Glyphosate affects the methylation of BMP3 gene

NCBI chr14:11,012,564...11,041,282
Ensembl chr14:11,016,620...11,041,282

G

bone morphogenetic protein 5

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of BMP5 gene
Glyphosate results in decreased expression of BMP5 mRNA

PMID:31295307 PMID:35440735

NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189

G

BMP-binding endothelial regulator

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BMPER mRNA

NCBI chr 8:30,008,049...30,253,201
Ensembl chr 8:30,008,148...30,434,359

G

bone morphogenetic protein receptor type 1A

decreases expression

ISO

Glyphosate results in decreased expression of BMPR1A mRNA

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

bone morphogenetic protein receptor type 1B

decreases expression

ISO

Glyphosate results in decreased expression of BMPR1B mRNA

NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:233,211,525...233,544,311

G

BCL2 interacting protein 3

decreases expression

ISO

Glyphosate results in decreased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 family apoptosis regulator BOK

affects methylation

EXP

Glyphosate affects the methylation of BOK gene

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833

G

bolA family member 1

increases expression
decreases methylation

ISO
EXP

Glyphosate results in increased expression of BOLA1 protein
Glyphosate results in decreased methylation of BOLA1 gene

PMID:31011160 PMID:37208198

NCBI chr 2:186,447,386...186,448,402
Ensembl chr 2:186,443,583...186,501,358

G

BRCA1 associated protein

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of BRAP mRNA
Glyphosate results in increased expression of BRAP mRNA

NCBI chr12:40,535,232...40,561,726
Ensembl chr12:40,535,232...40,561,726

G

BRCA1, DNA repair associated

decreases expression

ISO

Glyphosate results in decreased expression of BRCA1 mRNA

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

bromodomain containing 1

increases expression

EXP

Glyphosate results in increased expression of BRD1 mRNA

NCBI chr 7:121,653,859...121,701,700
Ensembl chr 7:121,653,859...121,701,700

G

bromodomain containing 4

increases expression
increases methylation

EXP

Glyphosate results in increased expression of BRD4 mRNA
Glyphosate results in increased methylation of BRD4 gene

PMID:26302742 PMID:31011160

NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923

G

BSD domain containing 1

increases methylation

EXP

Glyphosate results in increased methylation of BSDC1 gene

NCBI chr 5:147,083,044...147,113,997
Ensembl chr 5:147,079,838...147,114,241

G

basigin

decreases expression

ISO

Glyphosate results in decreased expression of BSG protein

NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005

G

bone marrow stromal cell antigen 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BST2 mRNA

NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967

G

BTB domain containing 8

increases methylation

EXP

Glyphosate results in increased methylation of BTBD8 gene

NCBI chr14:2,410,093...2,483,114
Ensembl chr14:2,410,093...2,479,202

G

BTG anti-proliferation factor 2

decreases expression

ISO

Glyphosate results in decreased expression of BTG2 mRNA

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690

G

BUD23, rRNA methyltransferase and ribosome maturation factor

increases methylation

EXP

Glyphosate results in increased methylation of BUD23 gene

NCBI chr12:27,266,093...27,277,300
Ensembl chr12:27,265,521...27,277,297

G

similar to human chromosome 1 open reading frame 146

increases expression

EXP

Glyphosate results in increased expression of C14H1ORF146 mRNA

NCBI chr14:2,375,311...2,395,331
Ensembl chr14:2,374,948...2,386,112

G

complement C1q B chain

increases expression
affects methylation

EXP

Glyphosate results in increased expression of C1QB mRNA
Glyphosate affects the methylation of C1QB gene

PMID:26302742 PMID:35440735

NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840

G

complement C1q C chain

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C1QC mRNA

NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468

G

C1q and TNF related 3

decreases expression

EXP

Glyphosate results in decreased expression of C1QTNF3 mRNA

NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559

G

complement C2

increases expression

ISO

Glyphosate results in increased expression of C2 mRNA

NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740

G

complement C3

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of C3 mRNA; Glyphosate results in increased expression of C3 protein
Glyphosate results in decreased expression of C3 mRNA

PMID:27463640 PMID:34850229 PMID:36608876

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

similar to human chromosome 11 open reading frame 91

increases expression

EXP

Glyphosate results in increased expression of C3H11ORF91 mRNA

NCBI chr 3:110,934,488...110,941,511
Ensembl chr 3:110,939,526...110,941,508

G

complement C4B

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of C4B mRNA

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement C7

increases methylation

EXP

Glyphosate results in increased methylation of C7 gene

NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672

G

similar to human chromosome 12 open reading frame 42

affects methylation

EXP

Glyphosate affects the methylation of C7H12ORF42 gene

NCBI chr 7:23,351,247...23,540,772
Ensembl chr 7:23,372,782...23,540,784

G

similar to human chromosome 11 open reading frame 54

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C8H11ORF54 mRNA

NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811

G

carbonic anhydrase 12

increases methylation
decreases expression

EXP

Glyphosate results in increased methylation of CAR12 gene
Glyphosate results in decreased expression of CAR12 mRNA

PMID:31011160 PMID:38314887

NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465

G

carbonic anhydrase 14

increases expression

ISO

Glyphosate results in increased expression of CAR14 mRNA

NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863

G

carbonic anhydrase 3

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of CAR3 protein
Glyphosate results in decreased expression of CAR3 mRNA

PMID:20045496 PMID:38314887

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

carbonic anhydrase 5B

increases methylation

EXP

Glyphosate results in increased methylation of CA5B gene

NCBI chr X:34,106,553...34,166,651
Ensembl chr X:34,067,403...34,166,653

G

calcium binding protein 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CABP4 mRNA

NCBI chr 1:210,857,223...210,872,431
Ensembl chr 1:210,858,133...210,862,632

G

calcium voltage-gated channel subunit alpha1 A

affects methylation

EXP

Glyphosate affects the methylation of CACNA1A gene

NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599

G

calcium voltage-gated channel subunit alpha1 D

decreases expression

ISO

Glyphosate results in decreased expression of CACNA1D mRNA

NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692

G

calcium voltage-gated channel subunit alpha1 E

decreases methylation

EXP

Glyphosate results in decreased methylation of CACNA1E gene

NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983

G

calcium voltage-gated channel auxiliary subunit alpha2delta 3

increases methylation

EXP

Glyphosate results in increased methylation of CACNA2D3 gene

NCBI chr16:4,105,048...4,919,037
Ensembl chr16:4,105,048...4,919,098

G

calcium voltage-gated channel auxiliary subunit alpha2delta 4

affects methylation

EXP

Glyphosate affects the methylation of CACNA2D4 gene

NCBI chr 4:154,080,877...154,197,369
Ensembl chr 4:154,080,877...154,193,778

G

calcium voltage-gated channel auxiliary subunit gamma 2

affects methylation

EXP

Glyphosate affects the methylation of CACNG2 gene

NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757

G

calcium voltage-gated channel auxiliary subunit gamma 7

increases expression

ISO

Glyphosate results in increased expression of CACNG7 mRNA

NCBI chr 1:74,715,483...74,746,669
Ensembl chr 1:74,715,483...74,746,669

G

calcium dependent secretion activator 2

affects methylation

EXP

Glyphosate affects the methylation of CADPS2 gene

NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004

G

cancer antigen 1

decreases expression

EXP

Glyphosate results in decreased expression of CAGE1 mRNA

NCBI chr17:26,995,671...27,033,740
Ensembl chr17:26,995,078...27,033,754

G

calcitonin-related polypeptide alpha

decreases expression

EXP

Glyphosate results in decreased expression of CALCA protein

NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529

G

calmodulin 2

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of CALM2 mRNA
Glyphosate results in increased expression of CALM2 protein

PMID:31295307 PMID:35897073 PMID:36173347

NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657

G

calmodulin 3

decreases expression

ISO

Glyphosate results in decreased expression of CALM3 mRNA

NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960

G

calmodulin-like 4

decreases expression

EXP

Glyphosate results in decreased expression of CALML4 mRNA

NCBI chr 8:72,218,870...72,230,650
Ensembl chr 8:72,218,613...72,230,650

G

calneuron 1

increases methylation

EXP

Glyphosate results in increased methylation of CALN1 gene

NCBI chr12:31,447,964...31,939,847

G

calreticulin 3

affects methylation

EXP

Glyphosate affects the methylation of CALR3 gene

NCBI chr16:17,430,105...17,456,777
Ensembl chr16:17,430,153...17,457,198

G

calreticulin 4

decreases expression

EXP

Glyphosate results in decreased expression of CALR4 mRNA

NCBI chr 5:129,216,293...129,251,077
Ensembl chr 5:129,190,608...129,251,060

G

calumenin

increases expression

ISO

Glyphosate results in increased expression of CALU protein

NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:58,914,421...58,941,956

G

calcium/calmodulin-dependent protein kinase ID

affects methylation

EXP

Glyphosate affects the methylation of CAMK1D gene

NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012

G

calcium/calmodulin-dependent protein kinase II alpha

increases expression

ISO

Glyphosate results in increased expression of CAMK2A mRNA

NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504

G

calcium/calmodulin-dependent protein kinase II beta

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of CAMK2B gene
Glyphosate results in increased expression of CAMK2B mRNA

PMID:31874349 PMID:35440735

NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485

G

calcium/calmodulin-dependent protein kinase II delta

increases expression

ISO

Glyphosate results in increased expression of CAMK2D mRNA

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276

G

calcium/calmodulin-dependent protein kinase II gamma

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAMK2G mRNA

NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310

G

calmodulin binding transcription activator 1

increases methylation

EXP

Glyphosate results in increased methylation of CAMTA1 gene

NCBI chr 5:166,791,639...167,639,502
Ensembl chr 5:166,793,101...167,639,733

G

calnexin

decreases expression

ISO

Glyphosate results in decreased expression of CANX protein

NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857

G

cyclase associated actin cytoskeleton regulatory protein 1

decreases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of CAP1 protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CAP1 mRNA

PMID:33854195 PMID:37208198

NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470

G

calpain 1

increases methylation
decreases expression

EXP
ISO

Glyphosate results in increased methylation of CAPN1 gene
Glyphosate results in decreased expression of CAPN1 mRNA

PMID:31011160 PMID:31295307

NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445

G

calpain 12

increases methylation

EXP

Glyphosate results in increased methylation of CAPN12 gene

NCBI chr 1:93,298,571...93,311,220
Ensembl chr 1:93,298,571...93,310,630

G

calcyphosine 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAPS2 mRNA

NCBI chr 7:49,467,320...49,525,465
Ensembl chr 7:49,464,885...49,525,465

G

calcyphosine-like

decreases expression

EXP

Glyphosate results in decreased expression of CAPSL mRNA

NCBI chr 2:60,122,162...60,152,692
Ensembl chr 2:60,138,589...60,152,838

G

capping actin protein of muscle Z-line subunit alpha 2

increases expression

ISO

Glyphosate results in increased expression of CAPZA2 protein

NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938

G

carbonic anhydrase 10

affects methylation

EXP

Glyphosate affects the methylation of CAR10 gene

NCBI chr10:78,551,067...79,053,421
Ensembl chr10:78,551,067...79,053,421

G

caspase recruitment domain family, member 10

increases expression

ISO

Glyphosate results in increased expression of CARD10 mRNA

NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:112,210,776...112,239,806

G

caspase recruitment domain family, member 11

affects methylation

EXP

Glyphosate affects the methylation of CARD11 gene

NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045

G

caspase recruitment domain family, member 9

increases expression

EXP

Glyphosate results in increased expression of CARD9 mRNA

NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:29,569,959...29,578,402

G

caspase 1

increases expression

ISO

Glyphosate results in increased expression of CASP1 mRNA

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 2

decreases expression

ISO

Glyphosate results in decreased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

increases cleavage
multiple interactions
decreases expression
decreases cleavage
increases activity
increases expression

ISO
EXP

Glyphosate results in increased cleavage of CASP3 protein
Melatonin inhibits the reaction [Glyphosate results in increased cleavage of CASP3 protein]; XAF1 protein affects the reaction [Glyphosate results in increased cleavage of CASP3 protein]
Glyphosate results in decreased expression of CASP3 protein
Glyphosate results in decreased cleavage of CASP3 protein
Glyphosate results in increased activity of CASP3 protein
Glyphosate results in increased expression of CASP3 mRNA
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein; [Glyphosate co-treated with Herbicides] results in increased activity of CASP3 protein
[Surface-Active Agents co-treated with Glyphosate] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of CASP3 protein]
Glyphosate results in increased expression of CASP3 mRNA; Glyphosate results in increased expression of CASP3 protein

PMID:19105591 PMID:19539684 PMID:22546541 PMID:22634143 PMID:23099315 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 6

increases expression

ISO

Glyphosate results in increased expression of CASP6 mRNA

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726

G

caspase 7

increases expression
multiple interactions
increases activity

ISO
EXP

Glyphosate results in increased expression of CASP7 mRNA
[Glyphosate co-treated with Herbicides] results in increased activity of CASP7 protein
[Surface-Active Agents co-treated with Glyphosate] results in increased activity of CASP7 protein
Glyphosate results in increased activity of CASP7 protein

PMID:19105591 PMID:19539684 PMID:23099315 PMID:31874349

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 8

multiple interactions
decreases expression

ISO
EXP

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein
Glyphosate results in decreased expression of CASP8 mRNA

PMID:32800223 PMID:38314887

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 9

increases expression
decreases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of CASP9 mRNA
Glyphosate results in decreased expression of CASP9 protein
[Surface-Active Agents co-treated with Glyphosate] results in increased activity of CASP9 protein

PMID:23099315 PMID:24073338 PMID:31874349

Ensembl chr 5:159,391,188...159,409,648

G

cytosolic arginine sensor for mTORC1 subunit 1

increases expression

ISO

Glyphosate results in increased expression of CASTOR1 mRNA

NCBI chr14:83,309,710...83,314,123
Ensembl chr14:83,309,504...83,314,127

G

catalase

increases activity
increases expression
multiple interactions
decreases expression
decreases activity

EXP
ISO

Glyphosate results in increased activity of CAT protein
Glyphosate results in increased expression of CAT mRNA
Melatonin inhibits the reaction [Glyphosate results in increased expression of CAT mRNA]
Glyphosate results in decreased expression of CAT mRNA; Glyphosate results in decreased expression of CAT protein
[Atrazine co-treated with Glyphosate] results in decreased activity of CAT protein; NOX1 protein affects the reaction [Glyphosate results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Glyphosate results in decreased activity of CAT protein]
Glyphosate results in increased expression of CAT protein

PMID:23820267 PMID:24999230 PMID:25403740 PMID:28627408 PMID:30245445 More...

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

ciliogenesis associated TTC17 interacting protein

decreases expression

EXP

Glyphosate results in decreased expression of CATIP mRNA

NCBI chr 9:83,395,095...83,402,743
Ensembl chr 9:83,394,896...83,402,740

G

cation channel, sperm associated 4

increases methylation

EXP

Glyphosate results in increased methylation of CATSPER4 gene

NCBI chr 5:151,711,415...151,731,083
Ensembl chr 5:151,711,194...151,730,750

G

cerebellin 2 precursor

decreases expression

EXP

Glyphosate results in decreased expression of CBLN2 mRNA

NCBI chr18:82,215,210...82,222,648
Ensembl chr18:82,215,220...82,222,648

G

cystathionine beta synthase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CBS mRNA

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066

G

chromobox 2

decreases methylation

EXP

Glyphosate results in decreased methylation of CBX2 gene

NCBI chr10:104,777,054...104,785,922
Ensembl chr10:104,777,056...104,785,926

G

chromobox 6

decreases methylation

EXP

Glyphosate results in decreased methylation of CBX6 gene

NCBI chr 7:113,253,364...113,263,413
Ensembl chr 7:113,253,364...113,263,413

G

coiled-coil domain containing 106

increases methylation

EXP

Glyphosate results in increased methylation of CCDC106 gene

NCBI chr 1:77,808,723...77,812,816
Ensembl chr 1:77,808,723...77,852,105

G

coiled-coil domain containing 107

increases expression

EXP

Glyphosate results in increased expression of CCDC107 mRNA

NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:62,544,714...62,548,709

G

coiled-coil domain containing 125

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCDC125 mRNA

NCBI chr 2:33,542,916...33,568,501
Ensembl chr 2:33,543,300...33,568,288

G

coiled-coil domain containing 138

decreases methylation

EXP

Glyphosate results in decreased methylation of CCDC138 gene

NCBI chr20:27,037,256...27,115,454
Ensembl chr20:27,038,349...27,115,452

G

coiled-coil domain containing 146

decreases expression

EXP

Glyphosate results in decreased expression of CCDC146 mRNA

NCBI chr 4:14,554,966...14,703,801
Ensembl chr 4:14,554,966...14,703,799

G

coiled-coil domain containing 148

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of CCDC148 gene
Glyphosate results in decreased expression of CCDC148 mRNA

PMID:35440735 PMID:38314887

NCBI chr 3:63,765,656...64,040,802
Ensembl chr 3:63,765,668...64,040,757

G

coiled-coil domain containing 166

decreases expression

EXP

Glyphosate results in decreased expression of CCDC166 mRNA

NCBI chr 7:109,574,271...109,576,074
Ensembl chr 7:109,574,273...109,576,074

G

coiled-coil domain containing 180

decreases expression

EXP

Glyphosate results in decreased expression of CCDC180 mRNA

NCBI chr 5:64,950,522...65,019,127
Ensembl chr 5:64,950,515...65,019,127

G

coiled-coil domain containing 181

increases methylation

EXP

Glyphosate results in increased methylation of CCDC181 gene

NCBI chr13:79,157,708...79,171,365
Ensembl chr13:79,157,697...79,171,364

G

coiled-coil domain containing 190

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CCDC190 mRNA

NCBI chr13:84,679,959...84,687,661
Ensembl chr13:84,679,986...84,687,658

G

coiled-coil domain containing 24

increases methylation

EXP

Glyphosate results in increased methylation of CCDC24 gene

NCBI chr 5:136,684,206...136,697,855
Ensembl chr 5:136,693,499...136,697,469

G

coiled-coil domain containing 3

decreases expression

EXP

Glyphosate results in decreased expression of CCDC3 mRNA

NCBI chr17:77,941,148...78,044,820
Ensembl chr17:77,944,977...78,044,470

G

coiled-coil domain containing 42

affects methylation

EXP

Glyphosate affects the methylation of CCDC42 gene

NCBI chr10:53,788,833...53,799,011
Ensembl chr10:53,787,810...53,808,417

G

coiled-coil domain containing 77

decreases expression

EXP

Glyphosate results in decreased expression of CCDC77 mRNA

NCBI chr 4:155,206,402...155,238,235
Ensembl chr 4:155,193,275...155,239,207

G

coiled-coil domain containing 7B

affects methylation

EXP

Glyphosate affects the methylation of CCDC7B gene

NCBI chr19:74,079,539...74,152,823
Ensembl chr19:74,079,566...74,152,821

G

coiled-coil domain containing 9

decreases expression

ISO

Glyphosate results in decreased expression of CCDC9 mRNA

NCBI chr 1:86,105,717...86,119,811
Ensembl chr 1:86,105,800...86,119,884

G

calicin

decreases expression

ISO

Glyphosate results in decreased expression of CCIN mRNA

NCBI chr 5:63,002,427...63,004,314
Ensembl chr 5:63,000,138...63,010,123

G

cholecystokinin B receptor

decreases expression

EXP

Glyphosate results in decreased expression of CCKBR mRNA

NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745

G

C-C motif chemokine ligand 2

multiple interactions
increases expression

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCL2 mRNA
Glyphosate results in increased expression of CCL2 mRNA

PMID:37567420 PMID:38763501

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 21

affects methylation

EXP

Glyphosate affects the methylation of CCL21 gene

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 27

decreases expression

ISO

Glyphosate results in decreased expression of CCL27A mRNA

NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522

G

cellular communication network factor 1

decreases expression

ISO

Glyphosate results in decreased expression of CCN1 mRNA

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

cyclin A2

decreases expression

ISO

Glyphosate results in decreased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin B1

multiple interactions
increases expression

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCNB1 mRNA
Glyphosate results in increased expression of CCNB1 protein

PMID:29890199 PMID:37567420

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin D1

increases expression
affects expression
multiple interactions

ISO

Glyphosate results in increased expression of CCND1 mRNA; Glyphosate results in increased expression of CCND1 protein
Glyphosate affects the expression of CCND1 mRNA
U 0126 inhibits the reaction [Glyphosate results in increased expression of CCND1 protein]

PMID:24073338 PMID:29890199 PMID:31295307 PMID:31751608

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin E1

increases expression
decreases expression

ISO

Glyphosate results in increased expression of CCNE1 protein
Glyphosate results in decreased expression of CCNE1 mRNA

PMID:24073338 PMID:29890199 PMID:31295307

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cyclin E2

decreases expression

ISO

Glyphosate results in decreased expression of CCNE2 mRNA

NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882

G

cyclin G1

decreases expression

EXP

Glyphosate results in decreased expression of CCNG1 protein

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

cyclin J-like

increases methylation

EXP

Glyphosate results in increased methylation of CCNJL gene

NCBI chr10:28,497,144...28,554,877
Ensembl chr10:28,496,990...28,554,877

G

cyclin L1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA

NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468

G

cyclin T2

increases expression

EXP

Glyphosate results in increased expression of CCNT2 mRNA

NCBI chr13:41,804,007...41,845,641
Ensembl chr13:41,804,046...41,844,488

G

C-C motif chemokine receptor 4

affects methylation

EXP

Glyphosate affects the methylation of CCR4 gene

NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642

G

C-C motif chemokine receptor 7

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501

G

C-C motif chemokine receptor like 2

decreases expression

ISO

Glyphosate results in decreased expression of CCRL2 mRNA

NCBI chr 8:119,912,671...119,915,313
Ensembl chr 8:119,911,288...119,922,380

G

coiled-coil serine-rich protein 1

decreases methylation

EXP

Glyphosate results in decreased methylation of CCSER1 gene

NCBI chr 4:91,483,896...92,720,439
Ensembl chr 4:91,483,770...92,718,789

G

chaperonin containing TCP1 subunit 4

decreases expression

ISO

Glyphosate results in decreased expression of CCT4 protein

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

chaperonin containing TCP1 subunit 8

decreases expression

ISO

Glyphosate results in decreased expression of CCT8 protein

NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328

G

CCZ1 homolog, vacuolar protein trafficking and biogenesis associated

increases expression

EXP

Glyphosate results in increased expression of CCZ1 mRNA

NCBI chr12:15,714,768...15,738,273
Ensembl chr12:15,714,748...15,738,268

G

CD101 molecule

increases methylation

EXP

Glyphosate results in increased methylation of CD101 gene

NCBI chr 2:191,109,782...191,148,184
Ensembl chr 2:191,110,637...191,148,149

G

CD14 molecule

decreases expression

ISO

Glyphosate results in decreased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

CD163 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD163 mRNA

NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146

G

CD19 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CD19 mRNA

NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:190,417,853...190,424,355

G

CD209a molecule

affects methylation

EXP

Glyphosate affects the methylation of CD209A gene

NCBI chr12:6,620,541...6,626,124
Ensembl chr12:6,620,541...6,626,124

G

Cd300a molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD300A mRNA

NCBI chr10:100,428,826...100,441,693
Ensembl chr10:100,428,826...100,442,958

G

CD33 molecule

affects methylation

EXP

Glyphosate affects the methylation of CD33 gene

NCBI chr 1:103,071,985...103,086,687
Ensembl chr 1:103,072,375...103,086,291

G

CD40 molecule

increases expression

ISO

Glyphosate results in increased expression of CD40 mRNA

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

CD40 ligand

increases expression

ISO

Glyphosate results in increased expression of CD40LG mRNA

NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475

G

CD44 molecule

increases expression

ISO

Glyphosate results in increased expression of CD44 mRNA

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

CD46 molecule

increases expression

ISO

Glyphosate results in increased expression of CD46 mRNA

NCBI chr13:109,104,122...109,134,903

G

Cd48 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD48 mRNA

NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942

G

CD52 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA

NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086

G

CD59b molecule

decreases expression

EXP

Glyphosate results in decreased expression of CD59 mRNA

NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310

G

Cd6 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD6 mRNA

NCBI chr 1:216,867,767...216,906,642
Ensembl chr 1:216,867,771...216,879,432

G

Cd63 molecule

decreases expression

ISO

Glyphosate results in decreased expression of CD63 mRNA

NCBI chr 7:1,909,538...1,924,937
Ensembl chr 7:1,922,169...1,924,938

G

CD74 molecule

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD74 mRNA

NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410

G

CD86 molecule

decreases expression

ISO

Glyphosate results in decreased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361

G

CD9 molecule

increases methylation

EXP

Glyphosate results in increased methylation of CD9 gene

NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444

G

cell division cycle 25A

decreases expression

ISO

Glyphosate results in decreased expression of CDC25A mRNA

NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:118,742,426...118,761,188

G

cell division cycle 25B

increases expression

ISO

Glyphosate results in increased expression of CDC25B mRNA

NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492

G

cell division cycle 37-like 1

increases expression

ISO

Glyphosate results in increased expression of CDC37L1 mRNA

NCBI chr 1:236,118,630...236,147,527
Ensembl chr 1:236,118,555...236,207,079

G

cell division cycle 42

decreases expression

EXP
ISO

Glyphosate results in decreased expression of CDC42 mRNA
Glyphosate results in decreased expression of CDC42 protein

PMID:26302742 PMID:37208198

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627

G

CDC42 binding protein kinase alpha

increases methylation

EXP

Glyphosate results in increased methylation of CDC42BPA gene

NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681

G

CDC42 effector protein 3

decreases expression

ISO

Glyphosate results in decreased expression of CDC42EP3 mRNA

NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540

G

CDC42 effector protein 4

increases methylation

EXP

Glyphosate results in increased methylation of CDC42EP4 gene

NCBI chr10:99,271,750...99,298,551
Ensembl chr10:99,267,540...99,300,168

G

cell division cycle 45

decreases expression

ISO

Glyphosate results in decreased expression of CDC45 mRNA

NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981

G

cell division cycle 6

decreases expression

ISO

Glyphosate results in decreased expression of CDC6 mRNA

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241

G

cell division cycle 7

decreases expression

ISO

Glyphosate results in decreased expression of CDC7 mRNA

NCBI chr14:2,949,538...2,969,656
Ensembl chr14:2,949,539...2,969,656

G

cadherin 1

increases expression

ISO

Glyphosate results in increased expression of CDH1 mRNA

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

cadherin 13

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of CDH13 gene
Glyphosate affects the methylation of CDH13 gene

PMID:31011160 PMID:35440735

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119

G

cadherin 22

affects methylation

EXP

Glyphosate affects the methylation of CDH22 gene

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

cadherin-related 23

increases expression

ISO

Glyphosate results in increased expression of CDH23 mRNA

NCBI chr20:28,783,124...29,165,624
Ensembl chr20:28,783,564...29,165,332

G

cadherin 9

affects methylation

EXP

Glyphosate affects the methylation of CDH9 gene

NCBI chr 2:67,954,708...68,094,371
Ensembl chr 2:67,955,166...68,094,365

G

cadherin-related family member 3

affects methylation

EXP

Glyphosate affects the methylation of CDHR3 gene

NCBI chr 6:55,369,215...55,429,454
Ensembl chr 6:55,369,851...55,429,458

G

cadherin-related family member 4

decreases expression

EXP

Glyphosate results in decreased expression of CDHR4 mRNA

NCBI chr 8:117,561,206...117,594,456
Ensembl chr 8:117,561,240...117,569,412

G

cyclin-dependent kinase 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin-dependent kinase 12

increases expression

EXP

Glyphosate results in increased expression of CDK12 mRNA

NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183

G

cyclin dependent kinase 2

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of CDK2 mRNA
Glyphosate results in increased expression of CDK2 protein

PMID:24073338 PMID:31295307

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase 4

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of CDK4 mRNA
Glyphosate results in increased expression of CDK4 protein

PMID:24073338 PMID:31295307

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase 6

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of CDK6 protein
Glyphosate results in decreased expression of CDK6 mRNA

PMID:24073338 PMID:38314887

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701

G

cyclin-dependent kinase 7

increases expression

ISO

Glyphosate results in increased expression of CDK7 mRNA

NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression
decreases methylation

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA
Glyphosate results in increased expression of CDKN1A mRNA; Glyphosate results in increased expression of CDKN1A protein
Glyphosate results in decreased methylation of CDKN1A promoter

PMID:31295307 PMID:31751608 PMID:33854195 PMID:35485992

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of CDKN1B protein
Glyphosate results in increased expression of CDKN1B mRNA

PMID:27486271 PMID:31295307

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

cyclin-dependent kinase inhibitor 2A

decreases expression

ISO

Glyphosate results in decreased expression of CDKN2A mRNA

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

cerebellar degeneration-related protein 2-like

increases expression

ISO

Glyphosate results in increased expression of CDR2L mRNA

NCBI chr10:101,123,777...101,137,634
Ensembl chr10:101,123,777...101,137,634

G

caudal type homeo box 1

affects methylation

EXP

Glyphosate affects the methylation of CDX1 gene

NCBI chr18:56,742,970...56,761,299
Ensembl chr18:56,742,984...56,761,299

G

chromodomain Y-like

increases methylation

EXP

Glyphosate results in increased methylation of CDYL gene

NCBI chr17:29,188,697...29,409,805
Ensembl chr17:29,188,698...29,409,757

G

CEA cell adhesion molecule 9

affects methylation

EXP

Glyphosate affects the methylation of CEACAM3 gene

NCBI chr 1:86,533,724...86,538,259
Ensembl chr 1:86,533,724...86,538,260

G

CCAAT/enhancer binding protein delta

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824

G

CUGBP, Elav-like family member 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CELF3 mRNA

NCBI chr 2:184,805,078...184,819,189
Ensembl chr 2:184,805,081...184,819,187

G

centromere protein W

decreases expression

EXP

Glyphosate results in decreased expression of CENPW mRNA

NCBI chr 1:29,353,939...29,359,109
Ensembl chr 1:29,353,970...29,359,109

G

centrosomal protein 104

affects methylation

EXP

Glyphosate affects the methylation of CEP104 gene

NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695

G

centrosomal protein 135

affects methylation

EXP

Glyphosate affects the methylation of CEP135 gene

NCBI chr14:31,884,774...31,950,050
Ensembl chr14:31,884,781...31,950,050

G

centrosomal protein 43

affects methylation

EXP

Glyphosate affects the methylation of CEP43 gene

NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:55,082,712...55,111,509

G

centrosomal protein 68

affects methylation

ISO

Glyphosate affects the methylation of CEP68 gene

NCBI chr14:98,649,993...98,671,892
Ensembl chr14:98,649,993...98,671,868

G

centrosomal protein 85

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CEP85 mRNA

NCBI chr 5:151,640,316...151,687,891
Ensembl chr 5:151,639,282...151,687,860

G

ceramide kinase

affects methylation
multiple interactions

EXP

Glyphosate affects the methylation of CERK gene
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CERK mRNA

PMID:33854195 PMID:35440735

NCBI chr 7:119,105,674...119,149,885
Ensembl chr 7:119,105,674...119,148,570

G

cilia and flagella associated protein 126

decreases expression

EXP

Glyphosate results in decreased expression of CFAP126 mRNA

NCBI chr13:86,059,142...86,075,034
Ensembl chr13:86,059,142...86,075,034

G

cilia and flagella associated protein 144

decreases expression

EXP

Glyphosate results in decreased expression of CFAP144 mRNA

NCBI chr10:44,009,412...44,019,281
Ensembl chr10:44,009,412...44,019,281

G

cilia and flagella associated protein 161

decreases expression

EXP

Glyphosate results in decreased expression of CFAP161 mRNA

NCBI chr 1:147,152,923...147,177,821
Ensembl chr 1:147,152,924...147,178,015

G

cilia and flagella associated protein 206

affects methylation

EXP

Glyphosate affects the methylation of CFAP206 gene

NCBI chr 5:54,050,697...54,095,438
Ensembl chr 5:54,050,701...54,095,383

G

cilia and flagella associated protein 300

decreases expression

EXP

Glyphosate results in decreased expression of CFAP300 mRNA

NCBI chr 8:13,465,016...13,483,679
Ensembl chr 8:13,464,984...13,483,839

G

cilia and flagella associated protein 44

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of CFAP44 gene
Glyphosate results in decreased expression of CFAP44 mRNA

PMID:35440735 PMID:38314887

NCBI chr11:69,704,997...69,789,998
Ensembl chr11:69,705,719...69,789,905

G

cilia and flagella associated protein 45

affects methylation

EXP

Glyphosate affects the methylation of CFAP45 gene

NCBI chr13:87,521,831...87,545,236
Ensembl chr13:87,521,518...87,545,234

G

cilia and flagella associated protein 54

affects methylation

EXP

Glyphosate affects the methylation of CFAP54 gene

NCBI chr 7:29,203,143...29,489,551
Ensembl chr 7:29,202,722...29,491,189

G

cilia and flagella associated protein 57

decreases expression

EXP

Glyphosate results in decreased expression of CFAP57 mRNA

NCBI chr 5:137,359,787...137,433,472
Ensembl chr 5:137,359,653...137,436,733

G

cilia and flagella associated protein 61

decreases expression

EXP

Glyphosate results in decreased expression of CFAP61 mRNA

NCBI chr 3:153,807,672...154,086,591
Ensembl chr 3:153,807,735...154,086,590

G

cilia and flagella associated protein 65

decreases expression

EXP

Glyphosate results in decreased expression of CFAP65 mRNA

NCBI chr 9:83,907,882...83,942,812
Ensembl chr 9:83,907,276...83,942,714

G

complement factor B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFB mRNA

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

cofilin 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFL1 mRNA

NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353

G

CASP8 and FADD-like apoptosis regulator

increases expression

ISO

Glyphosate results in increased expression of CFLAR mRNA

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

cingulin

decreases expression

ISO

Glyphosate results in decreased expression of CGN protein

NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635

G

coiled-coil-helix-coiled-coil-helix domain containing 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CHCHD10 mRNA

NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,277...12,745,677

G

coiled-coil-helix-coiled-coil-helix domain containing 5

affects methylation

EXP

Glyphosate affects the methylation of CHCHD5 gene

NCBI chr 3:136,815,034...136,819,230
Ensembl chr 3:136,815,048...136,821,914

G

chromodomain helicase DNA binding protein 1

affects methylation

EXP

Glyphosate affects the methylation of CHD1 gene

NCBI chr 1:65,334,905...65,402,270
Ensembl chr 1:65,335,218...65,401,280

G

chromodomain helicase DNA binding protein 5

decreases methylation

EXP

Glyphosate results in decreased methylation of CHD5 gene

NCBI chr 5:168,130,851...168,181,705
Ensembl chr 5:168,130,575...168,179,441

G

chromodomain helicase DNA binding protein 8

decreases expression

ISO

Glyphosate results in decreased expression of CHD8 mRNA

NCBI chr15:27,379,285...27,438,959
Ensembl chr15:27,379,285...27,417,851

G

checkpoint kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of CHEK1 mRNA

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359

G

checkpoint kinase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CHEK2 mRNA

NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667

G

calcium homeostasis endoplasmic reticulum protein like 1

increases expression

EXP

Glyphosate results in increased expression of CHERPL1 mRNA

G

cysteine-rich hydrophobic domain 1

decreases expression

ISO

Glyphosate results in decreased expression of CHIC1 mRNA

NCBI chr X:72,427,851...72,471,924
Ensembl chr X:72,427,851...72,471,924

G

charged multivesicular body protein 1A

affects methylation

ISO

Glyphosate affects the methylation of CHMP1A gene

NCBI chr19:68,146,672...68,154,952
Ensembl chr19:68,146,672...68,154,952

G

charged multivesicular body protein 4C

decreases expression

EXP

Glyphosate results in decreased expression of CHMP4C mRNA

NCBI chr 2:93,299,152...93,336,075
Ensembl chr 2:93,299,157...93,360,850

G

chordin-like 1

increases expression

EXP

Glyphosate results in increased expression of CHRDL1 mRNA

NCBI chr X:111,685,864...111,789,684
Ensembl chr X:111,685,866...111,789,661

G

cholinergic receptor, muscarinic 1

affects methylation

EXP

Glyphosate affects the methylation of CHRM1 gene

NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:214,995,872...215,020,602

G

cholinergic receptor, muscarinic 2

increases expression

ISO

Glyphosate results in increased expression of CHRM2 mRNA

NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464

G

cholinergic receptor, muscarinic 5

increases expression

ISO

Glyphosate results in increased expression of CHRM5 mRNA

NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166

G

cholinergic receptor nicotinic alpha 2 subunit

increases methylation

EXP

Glyphosate results in increased methylation of CHRNA2 gene

NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144

G

cholinergic receptor nicotinic alpha 3 subunit

decreases expression

EXP

Glyphosate results in decreased expression of CHRNA3 mRNA

NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:64,297,755...64,311,412

G

cholinergic receptor nicotinic alpha 6 subunit

increases expression

ISO

Glyphosate results in increased expression of CHRNA6 mRNA

NCBI chr16:71,400,615...71,407,315
Ensembl chr16:71,400,615...71,407,315

G

carbohydrate sulfotransferase 9

increases methylation

EXP

Glyphosate results in increased methylation of CHST9 gene

NCBI chr18:6,850,874...7,125,222
Ensembl chr18:6,851,831...7,125,161

G

chromosome transmission fidelity factor 8

decreases expression
affects expression

ISO

Glyphosate results in decreased expression of CHTF8 mRNA
Glyphosate affects the expression of CHTF8 mRNA

NCBI chr19:51,691,776...51,702,076
Ensembl chr19:51,678,543...51,707,144

G

cartilage intermediate layer protein

decreases expression

EXP

Glyphosate results in decreased expression of CILP mRNA

NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409

G

corepressor interacting with RBPJ, CIR1

increases expression

ISO

Glyphosate results in increased expression of CIRSR mRNA

NCBI chr 3:78,566,438...78,596,309
Ensembl chr 3:78,566,438...78,596,309

G

cold inducible RNA binding protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CIRBP mRNA

NCBI chr 7:10,184,515...10,189,623

G

ciliated left-right organizer metallopeptidase

decreases expression

EXP

Glyphosate results in decreased expression of CIROP mRNA

NCBI chr15:32,121,021...32,128,152
Ensembl chr15:32,121,021...32,128,152

G

CDGSH iron sulfur domain 1

decreases expression

ISO

Glyphosate results in decreased expression of CISD1 protein

NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042

G

citron rho-interacting serine/threonine kinase

increases methylation

EXP

Glyphosate results in increased methylation of CIT gene

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656

G

cytoskeleton associated protein 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CKAP2 mRNA

NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352

G

cardiotrophin-like cytokine factor 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLCF1 mRNA

NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064

G

claudin 1

decreases expression
multiple interactions

EXP

Glyphosate results in decreased expression of CLDN1 mRNA; Glyphosate results in decreased expression of CLDN1 protein
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of CLDN1 protein]

PMID:34906888 PMID:38314887

NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529

G

claudin 14

increases expression

EXP

Glyphosate results in increased expression of CLDN14 mRNA

NCBI chr11:46,701,940...46,799,049
Ensembl chr11:46,701,940...46,799,096

G

claudin 2

decreases expression

EXP

Glyphosate results in decreased expression of CLDN2 mRNA

NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377

G

claudin 5

decreases expression

ISO

Glyphosate results in decreased expression of CLDN5 protein

NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322

G

C-type lectin domain family 18, member A

decreases expression

EXP

Glyphosate results in decreased expression of CLEC18A mRNA

NCBI chr19:55,947,625...55,964,505
Ensembl chr19:55,947,223...55,965,323

G

C-type lectin domain family 2, member D

decreases methylation

EXP

Glyphosate results in decreased methylation of CLEC2D gene

NCBI chr 4:163,902,124...163,925,587
Ensembl chr 4:163,902,547...163,925,587

G

C-type lectin domain family 2 member D-like 1

decreases methylation

EXP

Glyphosate results in decreased methylation of CLEC2DL1 gene

NCBI chr 4:163,949,688...163,960,935

G

C-type lectin domain family 2, member G

increases expression
multiple interactions

EXP

Glyphosate results in increased expression of CLEC2G mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLEC2G mRNA

PMID:33854195 PMID:34850229

NCBI chr 4:164,303,865...164,313,737
Ensembl chr 4:164,300,076...164,314,591

G

C-type lectin domain family 4, member A

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLEC4N mRNA

NCBI chr 4:158,026,138...158,119,904
Ensembl chr 4:158,100,615...158,118,094

G

chloride intracellular channel 5

increases methylation

EXP

Glyphosate results in increased methylation of CLIC5 gene

NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780

G

clathrin interactor 1

decreases expression

ISO

Glyphosate results in decreased expression of CLINT1 protein

NCBI chr10:30,799,936...30,854,513
Ensembl chr10:30,799,971...30,854,508

G

CAP-GLY domain containing linker protein 2

affects methylation

EXP

Glyphosate affects the methylation of CLIP2 gene

NCBI chr12:27,798,289...27,863,486
Ensembl chr12:27,799,524...27,863,484

G

clock circadian regulator

decreases expression

ISO

Glyphosate results in decreased expression of CLOCK mRNA

NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

decreases expression

ISO

Glyphosate results in decreased expression of CLPX protein

NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762

G

claspin

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLSPN mRNA

NCBI chr 5:144,134,619...144,169,531
Ensembl chr 5:144,134,632...144,169,530

G

calsyntenin 2

affects methylation

EXP

Glyphosate affects the methylation of CLSTN2 gene

NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053

G

clusterin

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of CLU mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CLU mRNA

PMID:33854195 PMID:36608876

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860

G

clustered mitochondria homolog

increases expression

ISO

Glyphosate results in increased expression of CLUH protein

NCBI chr10:60,008,052...60,029,742
Ensembl chr10:60,008,119...60,029,742

G

citramalyl-CoA lyase

decreases expression

EXP

Glyphosate results in decreased expression of CLYBL mRNA

NCBI chr15:105,690,283...105,912,347
Ensembl chr15:105,690,295...105,912,345

G

cap methyltransferase 1

decreases methylation

EXP

Glyphosate results in decreased methylation of CMTR1 gene

NCBI chr20:7,724,286...7,784,787
Ensembl chr20:7,683,946...7,784,263

G

cardiomyopathy associated 5

affects methylation

EXP

Glyphosate affects the methylation of CMYA5 gene

NCBI chr 2:26,014,545...26,113,273
Ensembl chr 2:26,014,177...26,113,376

G

carnosine dipeptidase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CNDP2 mRNA

NCBI chr18:80,314,799...80,331,900
Ensembl chr18:80,314,801...80,331,900

G

Cnksr family member 3

increases methylation

EXP

Glyphosate results in increased methylation of CNKSR3 gene

NCBI chr 1:45,904,581...45,996,921
Ensembl chr 1:45,904,581...45,996,921

G

CCR4-NOT transcription complex, subunit 6 like 2

decreases expression

EXP

Glyphosate results in decreased expression of CNOT6L2 mRNA

NCBI chr10:34,520,768...34,531,728

G

CCR4-NOT transcription complex, subunit 7

decreases expression

EXP

Glyphosate results in decreased expression of CNOT7 mRNA

NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046

G

cannabinoid receptor interacting protein 1

affects methylation

EXP

Glyphosate affects the methylation of CNRIP1 gene

NCBI chr14:95,664,435...95,707,062
Ensembl chr14:95,664,774...95,694,371

G

contactin 2

increases expression

ISO
EXP

Glyphosate results in increased expression of CNTN2 mRNA

PMID:35897073 PMID:38314887

NCBI chr13:46,497,269...46,528,112
Ensembl chr13:46,499,396...46,528,027

G

contactin 4

decreases expression

ISO

Glyphosate results in decreased expression of CNTN4 mRNA

NCBI chr 4:140,180,696...141,177,771
Ensembl chr 4:140,596,284...141,177,766

G

contactin 5

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of CNTN5 gene
Glyphosate affects the methylation of CNTN5 gene

PMID:31011160 PMID:35440735

NCBI chr 8:15,017,424...16,249,418
Ensembl chr 8:15,018,927...15,969,060

G

contactin 6

affects methylation

EXP

Glyphosate affects the methylation of CNTN6 gene

NCBI chr 4:138,911,090...139,307,339
Ensembl chr 4:138,911,380...139,311,816

G

contactin associated protein family member 5B

decreases expression

EXP

Glyphosate results in decreased expression of CNTNAP5B mRNA

NCBI chr13:18,378,255...19,281,711
Ensembl chr13:18,378,368...19,281,711

G

cordon-bleu WH2 repeat protein

decreases expression

EXP

Glyphosate results in decreased expression of COBL mRNA

NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257

G

component of oligomeric golgi complex 5

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of COG5 gene
Glyphosate results in increased methylation of COG5 gene

PMID:31011160 PMID:35440735

NCBI chr 6:53,969,967...54,267,869
Ensembl chr 6:53,969,979...54,278,973

G

collagen type XI alpha 2 chain

affects methylation

EXP

Glyphosate affects the methylation of COL11A2 gene

NCBI chr20:4,788,829...4,818,492
Ensembl chr20:4,788,829...4,817,648

G

collagen type XIV alpha 1 chain

increases expression

ISO

Glyphosate results in increased expression of COL14A1 protein

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938

G

collagen type I alpha 1 chain

decreases expression

ISO

Glyphosate results in decreased expression of COL1A1 protein

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type XXV alpha 1 chain

affects methylation

EXP

Glyphosate affects the methylation of COL25A1 gene

NCBI chr 2:221,429,378...221,828,536
Ensembl chr 2:221,429,958...221,828,535

G

collagen type III alpha 1 chain

increases expression

ISO

Glyphosate results in increased expression of COL3A1 protein

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type V alpha 2 chain

affects methylation

EXP

Glyphosate affects the methylation of COL5A2 gene

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type VI alpha 6 chain

affects methylation

EXP

Glyphosate affects the methylation of COL6A6 gene

NCBI chr 8:115,196,833...115,352,161
Ensembl chr 8:115,197,464...115,352,136

G

collagen type VIII alpha 2 chain

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of COL8A2 mRNA

NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:143,870,742...143,897,884

G

COPI coat complex subunit alpha

increases expression
decreases expression

ISO

Glyphosate results in increased expression of COPA protein
Glyphosate results in decreased expression of COPA protein

PMID:36173347 PMID:37208198

NCBI chr13:87,078,853...87,119,256
Ensembl chr13:87,078,383...87,119,256

G

coenzyme Q7, hydroxylase

affects methylation

ISO

Glyphosate affects the methylation of COQ7 gene

NCBI chr 1:182,270,570...182,285,959
Ensembl chr 1:182,269,399...182,285,508

G

coactosin-like F-actin binding protein 1

increases methylation

EXP

Glyphosate results in increased methylation of COTL1 gene

NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840

G

cytochrome c oxidase assembly factor COX16

decreases expression

EXP

Glyphosate results in decreased expression of COX16 mRNA

NCBI chr 6:106,745,424...106,912,523
Ensembl chr 6:106,899,494...106,912,484

G

cytochrome c oxidase subunit 5A

decreases expression

ISO

Glyphosate results in decreased expression of COX5A protein

NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279

G

cytochrome c oxidase subunit 5B

increases expression

ISO

Glyphosate results in increased expression of COX5B protein

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403

G

cytochrome c oxidase subunit 6A2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of COX6A2 mRNA

NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716

G

cytochrome c oxidase subunit VIc, pseudogene

increases methylation

EXP

Glyphosate results in increased methylation of COX6C-PS1 gene

NCBI chr19:69,090,047...69,090,905
Ensembl chr19:69,090,047...69,090,905

G

cytochrome c oxidase subunit 7B2

affects methylation

EXP

Glyphosate affects the methylation of COX7B2 gene

NCBI chr14:37,047,081...37,159,288
Ensembl chr14:37,047,081...37,159,288

G

cytochrome c oxidase subunit 7C

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of COX7C mRNA
Glyphosate results in increased expression of COX7C protein

PMID:36173347 PMID:36608876

NCBI chr 2:18,577,145...18,579,170
Ensembl chr 2:18,577,149...18,579,170

G

carboxypeptidase A6

affects methylation

EXP

Glyphosate affects the methylation of CPA6 gene

NCBI chr 5:13,309,660...13,671,429
Ensembl chr 5:13,309,660...13,671,429

G

cytoplasmic polyadenylation element binding protein 3

increases expression

ISO

Glyphosate results in increased expression of CPEB3 mRNA

NCBI chr 1:244,161,690...244,343,765
Ensembl chr 1:244,161,690...244,343,561

G

complexin 3

decreases methylation

EXP

Glyphosate results in decreased methylation of CPLX3 gene

NCBI chr 8:66,899,438...66,906,200
Ensembl chr 8:66,899,438...66,906,200

G

carboxypeptidase M

increases expression

ISO

Glyphosate results in increased expression of CPM mRNA

NCBI chr 7:55,111,599...55,172,114
Ensembl chr 7:55,111,599...55,172,114

G

copine 1

increases expression

EXP

Glyphosate results in increased expression of CPNE1 mRNA

NCBI chr 3:165,047,615...165,089,994

G

copine 4

affects methylation

EXP

Glyphosate affects the methylation of CPNE4 gene

NCBI chr 8:114,056,152...114,531,855
Ensembl chr 8:113,993,703...114,531,855

G

carboxypeptidase Q

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of CPQ gene
Glyphosate results in decreased expression of PGCP mRNA

PMID:26302742 PMID:35440735

NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137

G

cleavage and polyadenylation specific factor 2

increases expression

EXP

Glyphosate results in increased expression of CPSF2 mRNA

NCBI chr 6:126,885,417...126,917,634
Ensembl chr 6:126,885,476...126,917,632

G

cleavage and polyadenylation specific factor 3

decreases expression

EXP

Glyphosate results in decreased expression of CPSF3 mRNA

NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136

G

cleavage and polyadenylation specific factor 7

increases expression

EXP

Glyphosate results in increased expression of CPSF7 mRNA

NCBI chr 1:216,592,745...216,616,860
Ensembl chr 1:216,592,463...216,616,855

G

carnitine palmitoyltransferase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818

G

carboxypeptidase, vitellogenic-like

affects methylation

EXP

Glyphosate affects the methylation of CPVL gene

NCBI chr 4:84,311,853...84,422,098
Ensembl chr 4:84,311,854...84,416,033

G

cAMP responsive element binding protein 1

decreases expression

ISO

Glyphosate results in decreased expression of CREB1 mRNA

NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339

G

cAMP responsive element binding protein 3-like 2

decreases expression

ISO

Glyphosate results in decreased expression of CREB3L2 mRNA

NCBI chr 4:66,874,623...66,990,962
Ensembl chr 4:66,387,126...66,990,832

G

cAMP responsive element binding protein 5

decreases expression

ISO

Glyphosate results in decreased expression of CREB5 mRNA

NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793

G

corticotropin releasing hormone receptor 1

affects methylation

EXP

Glyphosate affects the methylation of CRHR1 gene

NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466

G

carnitine O-octanoyltransferase

decreases expression

ISO

Glyphosate results in decreased expression of CROT protein

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064

G

cartilage associated protein

increases expression

ISO

Glyphosate results in increased expression of CRTAP mRNA

NCBI chr 8:122,926,117...122,945,843
Ensembl chr 8:122,926,117...122,945,843

G

CREB regulated transcription coactivator 2

increases expression

ISO

Glyphosate results in increased expression of CRTC2 mRNA

NCBI chr 2:178,007,233...178,017,397
Ensembl chr 2:178,007,240...178,017,389

G

cryptochrome circadian regulator 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CRY1 mRNA

NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822

G

crystallin zeta

increases methylation

EXP

Glyphosate results in increased methylation of CRYZ gene

NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:246,211,156...246,239,470

G

citrate synthase

decreases expression

ISO

Glyphosate results in decreased expression of CS mRNA

NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938

G

colony stimulating factor 1

increases expression

ISO

Glyphosate results in increased expression of CSF1 mRNA

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

centrosome and spindle pole associated protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSPP1 mRNA

NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321

G

cysteine and serine rich nuclear protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSRNP1 mRNA

NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469

G

cystatin C

increases expression

ISO

Glyphosate results in increased expression of CST3 protein

NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937

G

cystatin B

increases expression

ISO

Glyphosate results in increased expression of CSTB protein

NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199

G

C-terminal binding protein 2

decreases expression

ISO

Glyphosate results in decreased expression of CTBP2 mRNA
Glyphosate results in decreased expression of CTBP2 protein

PMID:31295307 PMID:37208198

NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261

G

CTD small phosphatase like

affects methylation

EXP

Glyphosate affects the methylation of CTDSPL gene

NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:127,520,499...127,644,999

G

cystathionine gamma-lyase

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of CTH protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of CTH gene

PMID:33854195 PMID:37208198

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066

G

cytotoxic T lymphocyte-associated protein 2 alpha

increases expression

EXP

Glyphosate results in increased expression of CTLA2A mRNA

NCBI chr17:3,809,052...3,828,872
Ensembl chr17:3,808,943...3,829,344

G

catenin alpha 2

affects methylation

EXP

Glyphosate affects the methylation of CTNNA2 gene

NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365

G

catenin alpha-like 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CTNNAL1 mRNA

NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637

G

catenin beta 1

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of CTNNB1 protein
Glyphosate results in increased expression of CTNNB1 protein
Glyphosate results in decreased expression of CTNNB1 mRNA

PMID:28780397 PMID:31295307 PMID:34906888

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

catenin, beta like 1

increases methylation

EXP

Glyphosate results in increased methylation of CTNNBL1 gene

NCBI chr 3:166,807,899...166,968,932
Ensembl chr 3:166,807,858...166,968,931

G

cathepsin B

increases expression

ISO

Glyphosate results in increased expression of CTSB mRNA

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cathepsin C

decreases expression

ISO

Glyphosate results in decreased expression of CTSC mRNA

NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082

G

cathepsin D

decreases expression

ISO

Glyphosate results in decreased expression of CTSD mRNA

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin H

decreases expression

EXP

Glyphosate results in decreased expression of CTSH mRNA

NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181

G

cathepsin L

decreases expression

ISO

Glyphosate results in decreased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113

G

cullin 1

decreases expression

ISO

Glyphosate results in decreased expression of CUL1 mRNA
Glyphosate results in decreased expression of CUL1 protein

PMID:31295307 PMID:37208198

NCBI chr 4:77,551,781...77,634,210
Ensembl chr 4:77,551,787...77,621,760

G

cullin 4A

decreases expression

ISO

Glyphosate results in decreased expression of CUL4A mRNA

NCBI chr16:83,086,688...83,124,503
Ensembl chr16:83,086,921...83,124,457

G

cut-like homeobox 2

multiple interactions
affects methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CUX2 mRNA
Glyphosate affects the methylation of CUX2 gene

PMID:33854195 PMID:35440735

NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528

G

C-X-C motif chemokine ligand 10

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 12

multiple interactions
decreases expression
increases expression

ISO

Glyphosate promotes the reaction [Estradiol results in decreased expression of CXCL12 mRNA]
Glyphosate results in decreased expression of CXCL12 mRNA
Glyphosate results in increased expression of CXCL12 mRNA

PMID:17984146 PMID:28711546

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 9

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

C-X-C motif chemokine receptor 4

increases methylation

EXP

Glyphosate results in increased methylation of CXCR4 gene

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459

G

CXXC finger protein 4

decreases expression

ISO

Glyphosate results in decreased expression of CXXC4 mRNA

NCBI chr 2:225,329,044...225,363,347

G

cytochrome b5 reductase-like

decreases expression

EXP

Glyphosate results in decreased expression of CYB5RL mRNA

NCBI chr 5:127,075,034...127,097,551
Ensembl chr 5:127,074,535...127,097,518

G

cytochrome b-245 chaperone 1

increases expression

ISO

Glyphosate results in increased expression of CYBC1 mRNA

NCBI chr10:106,997,018...107,003,895
Ensembl chr10:106,997,023...107,003,841

G

cytochrome c, somatic

multiple interactions

EXP
ISO

[Surface-Active Agents co-treated with Glyphosate] affects the localization of CYCS protein
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CYCS mRNA

PMID:23099315 PMID:32800223

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816

G

cytochrome c, testis

increases methylation
decreases expression

EXP
ISO

Glyphosate results in increased methylation of CYCT gene
Glyphosate results in decreased expression of CYCT mRNA

PMID:31011160 PMID:33713393

NCBI chr 3:81,697,333...81,704,401
Ensembl chr 3:81,697,333...81,700,514

G

CYLD lysine 63 deubiquitinase

increases expression

ISO

Glyphosate results in increased expression of CYLD mRNA

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression
decreases expression
decreases activity

ISO

Glyphosate results in increased expression of CYP11A1 mRNA
Glyphosate results in decreased expression of CYP11A1 mRNA
Glyphosate results in decreased activity of CYP11A1 protein

PMID:10964798 PMID:30245445 PMID:33957581

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression
decreases expression

ISO

Glyphosate results in increased expression of CYP17A1 protein
Glyphosate results in decreased expression of CYP17A1 mRNA

PMID:33957581 PMID:37208198

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression
increases expression
affects binding
decreases activity
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of CYP19A1 mRNA
Glyphosate results in increased expression of CYP19A1 mRNA
Glyphosate binds to CYP19A1 protein
Glyphosate results in decreased activity of CYP19A1 protein
[Glyphosate co-treated with Herbicides] affects the activity of CYP19A1 protein; [Glyphosate co-treated with Herbicides] affects the expression of CYP19A1 mRNA
Glyphosate results in increased expression of CYP19A1 mRNA; Glyphosate results in increased expression of CYP19A1 protein

PMID:15929894 PMID:17486286 PMID:19539684 PMID:24930125 PMID:30245445 More...

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917

G

cytochrome P450, family 1, subfamily a, polypeptide 1

affects response to substance
decreases expression
multiple interactions

ISO

CYP1A1 gene SNP affects the susceptibility to Glyphosate
Glyphosate results in decreased expression of CYP1A1 mRNA
CYP1A1 gene SNP promotes the reaction [Glyphosate results in decreased activity of BCHE protein]

PMID:31836050 PMID:33348142

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 2, subfamily a, polypeptide 3

decreases expression

ISO

Glyphosate results in decreased expression of CYP2A4 protein

NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649

G

cytochrome P450, family 2, subfamily b, polypeptide 12

increases methylation

EXP

Glyphosate results in increased methylation of CYP2B12 gene

NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression

ISO

Glyphosate results in increased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily c, polypeptide 22

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP2C22 mRNA

NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182

G

cytochrome P450, family 2, subfamily c, polypeptide 23

decreases expression

EXP

Glyphosate results in decreased expression of CYP2C23 mRNA

NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

ISO

Glyphosate results in decreased expression of CYP2D22 protein

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases methylation

EXP

Glyphosate results in increased methylation of CYP2E1 gene

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily s, polypeptide 1

affects methylation

EXP

Glyphosate affects the methylation of CYP2S1 gene

NCBI chr 1:90,437,741...90,453,073
Ensembl chr 1:90,438,224...90,453,073

G

cytochrome P450, family 46, subfamily a, polypeptide 1

affects methylation

EXP

Glyphosate affects the methylation of CYP46A1 gene

NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971

G

cytochrome P450, family 4, subfamily a, polypeptide 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4A1 mRNA

NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231

G

cytochrome P450, family 4, subfamily f, polypeptide 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4F1 mRNA

NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612

G

cysteinyl leukotriene receptor 2

decreases expression

EXP

Glyphosate results in decreased expression of CYSLTR2 mRNA

NCBI chr15:54,599,043...54,638,314
Ensembl chr15:54,598,818...54,713,597

G

cysteine-rich transmembrane module containing 1

affects methylation

EXP

Glyphosate affects the methylation of CYSTM1 gene

NCBI chr18:28,219,861...28,287,574
Ensembl chr18:28,220,004...28,287,574

G

cytohesin 3

affects methylation

EXP

Glyphosate affects the methylation of CYTH3 gene

NCBI chr12:15,953,781...16,076,584
Ensembl chr12:15,953,791...16,047,506

G

cytohesin 1 interacting protein

multiple interactions
decreases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CYTIP mRNA
Glyphosate results in decreased expression of CYTIP mRNA

PMID:33854195 PMID:38314887

NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832

G

dishevelled associated activator of morphogenesis 1

decreases expression

ISO

Glyphosate results in decreased expression of DAAM1 mRNA

NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049

G

dishevelled associated activator of morphogenesis 2

increases expression

ISO

Glyphosate results in increased expression of DAAM2 mRNA

NCBI chr 9:18,926,620...19,044,672
Ensembl chr 9:18,926,623...19,044,671

G

DAB adaptor protein 1

increases expression

EXP

Glyphosate results in increased expression of DAB1 mRNA

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584

G

dishevelled-binding antagonist of beta-catenin 3

decreases methylation

EXP

Glyphosate results in decreased methylation of DACT3 gene

NCBI chr 1:86,674,989...86,686,722
Ensembl chr 1:86,674,734...86,687,421

G

dynein assembly factor with WD repeats 1

decreases expression

EXP

Glyphosate results in decreased expression of DAW1 mRNA

NCBI chr 9:91,883,656...91,920,733
Ensembl chr 9:91,881,067...91,921,349

G

DAZ associated protein 2

affects methylation

EXP

Glyphosate affects the methylation of DAZAP2 gene

NCBI chr 7:133,593,503...133,599,044
Ensembl chr 7:133,593,512...133,599,047

G

deleted in azoospermia-like

increases expression

ISO

Glyphosate results in increased expression of DAZL mRNA

NCBI chr 9:18,193,363...18,210,100
Ensembl chr 9:18,193,363...18,210,100

G

D-box binding PAR bZIP transcription factor

decreases expression
affects expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of DBP mRNA
Glyphosate affects the expression of DBP mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DBP mRNA

PMID:33854195 PMID:33957581 PMID:35897073

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205

G

dihydrolipoamide branched chain transacylase E2

increases expression

ISO

Glyphosate results in increased expression of DBT protein

NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525

G

DDB1 and CUL4 associated factor 17

affects methylation

EXP

Glyphosate affects the methylation of DCAF17 gene

NCBI chr 3:76,271,503...76,303,321
Ensembl chr 3:76,271,519...76,303,320

G

DDB1 and CUL4 associated factor 4

decreases methylation

EXP

Glyphosate results in decreased methylation of DCAF4 gene

NCBI chr 6:108,885,970...108,912,116
Ensembl chr 6:108,885,932...108,912,110

G

dachsous cadherin-related 2

affects methylation

EXP

Glyphosate affects the methylation of DCHS2 gene

NCBI chr 2:170,775,818...170,983,844
Ensembl chr 2:170,776,682...170,981,770

G

DNA cross-link repair 1B

increases expression

ISO

Glyphosate results in increased expression of DCLRE1B mRNA

NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864

G

DNA cross-link repair 1C

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DCLRE1C mRNA

NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734

G

decapping enzyme, scavenger

decreases methylation

EXP

Glyphosate results in decreased methylation of DCPS gene

NCBI chr 8:41,729,507...41,782,222
Ensembl chr 8:41,724,563...41,782,222

G

dCMP deaminase

increases methylation

EXP

Glyphosate results in increased methylation of DCTD gene

NCBI chr16:50,799,699...50,831,398
Ensembl chr16:50,787,875...50,831,186

G

dynactin subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of DCTN1 protein

NCBI chr 4:117,228,722...117,261,528
Ensembl chr 4:117,219,349...117,261,528

G

doublecortin

affects expression

ISO

Glyphosate affects the expression of DCX mRNA

NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161

G

dimethylarginine dimethylaminohydrolase 1

decreases expression

ISO

Glyphosate results in decreased expression of DDAH1 protein

NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626

G

dopa decarboxylase

increases expression
affects binding

ISO

Glyphosate results in increased expression of DDC mRNA
Glyphosate binds to [DDC protein binds to Pyridoxal Phosphate]; Glyphosate binds to DDC protein

PMID:35151785 PMID:35897073

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806

G

DNA-damage inducible transcript 3

increases expression

ISO
EXP

Glyphosate results in increased expression of DDIT3 mRNA

PMID:31295307 PMID:34906888

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4

increases expression

ISO

Glyphosate results in increased expression of DDIT4 mRNA

PMID:31295307 PMID:35897073

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037

G

DEAD-box helicase 20

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX20 mRNA

NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:195,847,105...195,855,461

G

DExD-box helicase 39A

increases expression

EXP

Glyphosate results in increased expression of DDX39A mRNA

NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306

G

DExD-box helicase 39B

increases expression

EXP

Glyphosate results in increased expression of DDX39B mRNA

NCBI chr20:3,577,200...3,589,651
Ensembl chr20:3,576,734...3,589,651

G

DEAD-box helicase 3, X-linked

decreases expression

ISO

Glyphosate results in decreased expression of DDX3X protein

NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983

G

DEAD box helicase 3, Y-linked

increases expression

EXP

Glyphosate results in increased expression of DDX3Y mRNA

NCBI chr Y:1,190,042...1,210,699
Ensembl chr Y:1,191,242...1,210,650

G

DEAD-box helicase 5

multiple interactions
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX5 mRNA
Glyphosate results in decreased expression of DDX5 mRNA

PMID:33854195 PMID:35897073

NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300

G

DEAD-box helicase 6

decreases expression

ISO

Glyphosate results in decreased expression of DDX6 protein

NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977

G

defensin beta 24

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DEFB19 mRNA

NCBI chr 3:161,506,850...161,512,983
Ensembl chr 3:161,506,851...161,512,983

G

DENN domain containing 4A

increases expression

ISO

Glyphosate results in increased expression of DENND4A mRNA

NCBI chr 8:74,218,131...74,331,543
Ensembl chr 8:74,218,191...74,331,542

G

desmin

increases expression

ISO

Glyphosate results in increased expression of DES protein

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347

G

DNA fragmentation factor subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of DFFA mRNA

NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728

G

DNA fragmentation factor subunit beta

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DFFB mRNA

NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225

G

D-glutamate cyclase

increases expression

ISO

Glyphosate results in increased expression of DGLUCY protein

NCBI chr 6:125,785,075...125,860,496
Ensembl chr 6:125,785,087...125,860,496

G

dihydrofolate reductase

affects methylation

EXP

Glyphosate affects the methylation of DHFR gene

NCBI chr 2:25,320,895...25,346,004

G

dehydrogenase/reductase 1

decreases expression

ISO

Glyphosate results in decreased expression of DHRS1 protein

NCBI chr15:33,206,449...33,213,776
Ensembl chr15:33,206,451...33,213,734

G

dehydrogenase/reductase member 2 like 1

increases methylation

EXP

Glyphosate results in increased methylation of DHRS2L1 gene

NCBI chr15:32,605,149...32,608,039
Ensembl chr15:32,605,149...32,608,039

G

DEXH-box helicase 58

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DHX58 mRNA

NCBI chr10:86,120,677...86,132,095
Ensembl chr10:86,120,677...86,131,844

G

iodothyronine deiodinase 2

affects expression
multiple interactions

EXP
ISO

Glyphosate affects the expression of DIO2 mRNA
Melatonin inhibits the reaction [Glyphosate affects the expression of DIO2 mRNA]

PMID:27916585 PMID:33159990

NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594

G

iodothyronine deiodinase 3

decreases expression

EXP

Glyphosate results in decreased expression of DIO3 mRNA

PMID:27916585 PMID:33512083

NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985

G

DIRAS family GTPase 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DIRAS2 mRNA

NCBI chr17:12,882,224...12,913,366
Ensembl chr17:12,880,385...12,914,291

G

dispatched RND transporter family member 2

increases expression

ISO

Glyphosate results in increased expression of DISP2 mRNA

NCBI chr 3:126,216,194...126,231,724
Ensembl chr 3:126,216,218...126,231,711

G

dyskerin pseudouridine synthase 1

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of DKC1 gene
Glyphosate results in increased expression of DKC1 protein

PMID:35440735 PMID:37208198

NCBI chr  X:157,751,651...157,757,796
Ensembl chr  Y:380,743...385,405
Ensembl chr  X:380,743...385,405

G

dickkopf WNT signaling pathway inhibitor 1

increases expression
decreases expression

EXP
ISO

Glyphosate results in increased expression of DKK1 mRNA
Glyphosate results in decreased expression of DKK1 mRNA

PMID:28780397 PMID:31295307 PMID:35485992

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650

G

deleted in lymphocytic leukemia, 7

decreases methylation

EXP

Glyphosate results in decreased methylation of DLEU7 gene

NCBI chr15:40,655,563...40,671,759
Ensembl chr15:40,655,563...40,671,759

G

discs large MAGUK scaffold protein 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DLG2 gene

NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215

G

delta like non-canonical Notch ligand 1

increases expression

ISO

Glyphosate results in increased expression of DLK1 mRNA

NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529

G

delta like canonical Notch ligand 1

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of DLL1 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DLL1 mRNA

PMID:31295307 PMID:33854195

NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276

G

dimethylglycine dehydrogenase

increases expression

ISO

Glyphosate results in increased expression of DMGDH protein

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071

G

doublesex and mab-3 related transcription factor 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DMRT3 gene

NCBI chr 1:232,670,642...232,690,557
Ensembl chr 1:232,675,059...232,688,833

G

dynein axonemal assembly factor 4

decreases expression

EXP

Glyphosate results in decreased expression of DNAAF4 mRNA

NCBI chr 8:82,577,044...82,601,653
Ensembl chr 8:82,578,755...82,592,205

G

dynein, axonemal, heavy chain 11

increases methylation

EXP

Glyphosate results in increased methylation of DNAH11 gene

NCBI chr 6:144,982,130...145,298,523
Ensembl chr 6:144,973,797...145,298,692

G

dynein, axonemal, heavy chain 2

affects methylation

EXP

Glyphosate affects the methylation of DNAH2 gene

NCBI chr10:54,641,450...54,766,502
Ensembl chr10:54,641,450...54,766,026

G

dynein, axonemal, heavy chain 3

decreases expression

EXP

Glyphosate results in decreased expression of DNAH3 mRNA

NCBI chr 1:183,738,013...183,910,831
Ensembl chr 1:183,738,013...183,910,432

G

dynein, axonemal, heavy chain 6

decreases expression

EXP

Glyphosate results in decreased expression of DNAH6 mRNA

NCBI chr 4:106,622,235...106,842,461
Ensembl chr 4:106,612,973...106,842,417

G

dynein, axonemal, heavy chain 7

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of DNAH7B protein
Glyphosate results in decreased expression of DNAH7 mRNA

PMID:37208198 PMID:38314887

NCBI chr 9:62,454,838...62,760,504
Ensembl chr 9:62,454,838...62,756,730

G

dynein axonemal intermediate chain 3

decreases expression

EXP

Glyphosate results in decreased expression of DNAI3 mRNA

NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:237,604,068...237,666,465

G

DnaJ heat shock protein family (Hsp40) member A2

decreases expression

ISO

Glyphosate results in decreased expression of DNAJA2 protein

NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

DnaJ heat shock protein family (Hsp40) member B9

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB9 mRNA

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C30

increases methylation

EXP

Glyphosate results in increased methylation of DNAJC30 gene

NCBI chr12:27,264,861...27,265,940
Ensembl chr12:27,262,802...27,266,169

G

deoxyribonuclease 1

increases expression

ISO

Glyphosate results in increased expression of DNASE1 mRNA

NCBI chr10:12,005,305...12,030,615
Ensembl chr10:12,005,306...12,010,497

G

deoxyribonuclease 1L3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DNASE1L3 mRNA

NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531

G

deoxyribonuclease 2 beta

decreases methylation

EXP

Glyphosate results in decreased methylation of DNASE2B gene

NCBI chr 2:238,131,182...238,168,041
Ensembl chr 2:238,131,185...238,146,558

G

delta/notch-like EGF repeat containing

affects methylation

EXP

Glyphosate affects the methylation of DNER gene

NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:93,035,108...93,350,568

G

dynamin 3

decreases methylation

EXP

Glyphosate results in decreased methylation of DNM3 gene

NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350

G

DNA methyltransferase 1

increases expression

ISO

Glyphosate results in increased expression of DNMT1 mRNA

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119

G

DNA methyltransferase 3 alpha

increases expression
increases methylation

EXP
ISO

Glyphosate results in increased expression of DNMT3A mRNA
Glyphosate results in increased methylation of DNMT3A gene

PMID:26302742 PMID:31011160 PMID:33512083 PMID:33803994 PMID:34542374

NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970

G

DNA methyltransferase 3 beta

increases expression

EXP

Glyphosate results in increased expression of DNMT3B mRNA

NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313

G

double C2 domain alpha

increases expression

EXP

Glyphosate results in increased expression of DOC2A mRNA

NCBI chr 1:190,887,306...190,893,057
Ensembl chr 1:190,888,214...190,893,384

G

dedicator of cytokinesis 5

increases expression

ISO

Glyphosate results in increased expression of DOCK5 mRNA

NCBI chr15:46,155,124...46,334,127
Ensembl chr15:46,155,125...46,334,042

G

dedicator of cytokinesis 9

increases methylation

EXP

Glyphosate results in increased methylation of DOCK9 gene

NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799

G

DOT1 like histone lysine methyltransferase

increases expression

EXP

Glyphosate results in increased expression of DOT1L mRNA

NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:9,569,439...9,607,095

G

dipeptidyl peptidase like 10

affects methylation

EXP

Glyphosate affects the methylation of DPP10 gene

NCBI chr13:37,145,531...38,821,987
Ensembl chr13:37,145,531...38,822,801

G

dipeptidylpeptidase 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DPP4 mRNA

NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422

G

dipeptidyl peptidase like 6

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DPP6 mRNA

NCBI chr 4:8,323,220...9,242,694
Ensembl chr 4:8,324,843...9,242,209

G

developmental pluripotency associated 4

affects methylation

EXP

Glyphosate affects the methylation of DPPA4 gene

NCBI chr11:66,033,256...66,041,754
Ensembl chr11:66,033,256...66,041,754

G

dpy-19 like C-mannosyltransferase 3

decreases methylation

EXP

Glyphosate results in decreased methylation of DPY19L3 gene

NCBI chr 1:97,487,206...97,554,232
Ensembl chr 1:97,487,206...97,554,232

G

dpy-19 like 4

decreases methylation

EXP

Glyphosate results in decreased methylation of DPY19L4 gene

NCBI chr 5:29,148,518...29,208,132
Ensembl chr 5:29,151,129...29,208,132

G

dpy-30 histone methyltransferase complex regulatory subunit

increases methylation

EXP

Glyphosate results in increased methylation of DPY30 gene

NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930

G

dihydropyrimidinase-like 2

decreases expression

ISO

Glyphosate results in decreased expression of DPYSL2 protein

NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065

G

dynein regulatory complex subunit 12 homolog

decreases expression

EXP

Glyphosate results in decreased expression of DRC12 mRNA

NCBI chr 8:53,468,344...53,481,168
Ensembl chr 8:53,472,849...53,486,567

G

dynein regulatory complex subunit 7

decreases expression

EXP

Glyphosate results in decreased expression of DRC7 mRNA

NCBI chr19:9,949,484...9,967,296
Ensembl chr19:9,949,486...9,967,192

G

dopamine receptor D1

multiple interactions

EXP

Glyphosate inhibits the reaction [SCH 23390 binds to DRD1 protein]

NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166

G

dopamine receptor D4

decreases expression

ISO

Glyphosate results in decreased expression of DRD4 mRNA

NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458

G

DS cell adhesion molecule

increases methylation

EXP

Glyphosate results in increased methylation of DSCAM gene

NCBI chr11:49,391,385...49,976,861
Ensembl chr11:49,347,531...49,976,238

G

desmoglein 2

increases expression

ISO

Glyphosate results in increased expression of DSG2 mRNA

NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590

G

death domain containing 1

decreases expression

EXP

Glyphosate results in decreased expression of DTHD1 mRNA

NCBI chr14:50,773,694...50,877,217

G

dystrobrevin binding protein 1

affects methylation

EXP

Glyphosate affects the methylation of DTNBP1 gene

NCBI chr17:19,891,313...19,982,770
Ensembl chr17:19,891,337...19,984,418

G

deltex E3 ubiquitin ligase 3

increases expression

ISO

Glyphosate results in increased expression of DTX3 mRNA

NCBI chr 7:64,898,693...64,904,636
Ensembl chr 7:64,898,866...64,903,752

G

dual oxidase maturation factor 1

increases expression

ISO

Glyphosate results in increased expression of DUOXA1 mRNA

NCBI chr 3:129,703,416...129,714,110
Ensembl chr 3:129,703,416...129,706,829

G

dual specificity phosphatase 1

increases expression
multiple interactions
affects expression
decreases expression

EXP
ISO

Glyphosate results in increased expression of DUSP1 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP1 mRNA
Glyphosate affects the expression of DUSP1 mRNA
Glyphosate results in decreased expression of DUSP1 mRNA

PMID:31295307 PMID:33854195 PMID:34850229 PMID:35897073

NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644

G

dual specificity phosphatase 10

decreases expression

ISO

Glyphosate results in decreased expression of DUSP10 mRNA

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304

G

dual specificity phosphatase 11

increases expression

ISO

Glyphosate results in increased expression of DUSP11 mRNA

NCBI chr 4:119,928,533...119,942,643
Ensembl chr 4:119,928,537...119,942,567

G

dual specificity phosphatase 16

decreases expression

ISO

Glyphosate results in decreased expression of DUSP16 mRNA

NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508

G

dual specificity phosphatase 2

increases expression
decreases expression

ISO

Glyphosate results in increased expression of DUSP2 mRNA
Glyphosate results in decreased expression of DUSP2 mRNA

NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809

G

dual specificity phosphatase 4

affects expression

ISO

Glyphosate affects the expression of DUSP4 mRNA

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700

G

dual specificity phosphatase 5

affects expression
multiple interactions

ISO
EXP

Glyphosate affects the expression of DUSP5 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DUSP5 gene

PMID:31295307 PMID:33854195

NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417

G

dual specificity phosphatase 6

multiple interactions
increases expression
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP6 mRNA
Glyphosate results in increased expression of DUSP6 mRNA
Glyphosate results in decreased expression of DUSP6 mRNA

PMID:31295307 PMID:33854195 PMID:34850229

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

dual specificity phosphatase 7

increases methylation

EXP

Glyphosate results in increased methylation of DUSP7 gene

NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:115,887,892...115,895,126

G

dual specificity phosphatase 8

affects expression

ISO

Glyphosate affects the expression of DUSP8 mRNA

NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441

G

dishevelled segment polarity protein 2

increases expression

ISO

Glyphosate results in increased expression of DVL2 mRNA

NCBI chr10:55,222,245...55,231,506
Ensembl chr10:55,222,056...55,231,506

G

dishevelled segment polarity protein 3

increases expression

ISO

Glyphosate results in increased expression of DVL3 mRNA

NCBI chr11:93,869,834...93,887,013
Ensembl chr11:93,869,834...93,886,903

G

decapping exoribonuclease

decreases expression

ISO

Glyphosate results in decreased expression of DXO mRNA

NCBI chr20:3,997,953...4,000,115
Ensembl chr20:3,997,955...4,000,037

G

dymeclin

decreases methylation

EXP

Glyphosate results in decreased methylation of DYM gene

NCBI chr18:70,879,835...71,176,006
Ensembl chr18:70,880,255...71,176,004

G

dynein cytoplasmic 1 heavy chain 1

decreases methylation

EXP

Glyphosate results in decreased methylation of DYNC1H1 gene

NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116

G

dynein light chain roadblock-type 2

decreases expression

EXP

Glyphosate results in decreased expression of DYNLRB2 mRNA

NCBI chr19:61,428,782...61,440,331
Ensembl chr19:61,429,065...61,441,071

G

dynein light chain Tctex-type family member 5

decreases expression

EXP

Glyphosate results in decreased expression of DYNLT5 mRNA

NCBI chr 5:122,964,568...122,987,304
Ensembl chr 5:122,964,845...122,987,304

G

DAZ interacting zinc finger protein 1

increases expression
decreases methylation

ISO
EXP

Glyphosate results in increased expression of DZIP1 mRNA
Glyphosate results in decreased methylation of DZIP1 gene

PMID:31011160 PMID:35897073

NCBI chr15:102,363,392...102,417,085
Ensembl chr15:102,363,392...102,417,085

G

DAZ interacting zinc finger protein 1-like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DZIP1L gene

NCBI chr 8:109,067,466...109,108,390
Ensembl chr 8:109,067,775...109,108,393

G

E2F transcription factor 1

decreases expression

ISO

Glyphosate results in decreased expression of E2F1 mRNA

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

E2F transcription factor 3

decreases expression

ISO

Glyphosate results in decreased expression of E2F3 mRNA

NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725

G

E2F transcription factor 4

decreases expression

ISO

Glyphosate results in decreased expression of E2F4 mRNA

NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834

G

EBF transcription factor 2

decreases expression

ISO
EXP

Glyphosate results in decreased expression of EBF2 mRNA

PMID:35489704 PMID:38314887

NCBI chr15:45,610,949...45,809,828
Ensembl chr15:45,610,949...45,809,822

G

enoyl CoA hydratase domain containing 3

decreases expression

ISO

Glyphosate results in decreased expression of ECHDC3 protein

NCBI chr17:76,980,112...77,002,934
Ensembl chr17:76,980,083...77,002,934

G

ectodysplasin A2 receptor

decreases methylation

EXP

Glyphosate results in decreased methylation of EDA2R gene

NCBI chr X:66,225,557...66,280,674
Ensembl chr X:66,236,111...66,280,663

G

EGF like repeats and discoidin domains 3

increases methylation

EXP

Glyphosate results in increased methylation of EDIL3 gene

NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379

G

eukaryotic translation elongation factor 1 alpha 1

increases expression

ISO

Glyphosate results in increased expression of EEF1A1 protein

NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072

G

eukaryotic translation elongation factor 1 alpha 2

decreases expression

ISO

Glyphosate results in decreased expression of EEF1A2 protein

NCBI chr 3:188,643,455...188,652,633
Ensembl chr 3:188,643,458...188,677,712

G

eukaryotic translation elongation factor 2

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of EEF2 protein
Glyphosate results in increased expression of EEF2 protein

NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544

G

eukaryotic elongation factor 2 lysine methyltransferase

increases expression

EXP

Glyphosate results in increased expression of EEF2KMT mRNA

NCBI chr10:10,843,429...10,853,800
Ensembl chr10:10,843,460...10,853,797

G

EF-hand calcium binding domain 10

decreases expression

EXP

Glyphosate results in decreased expression of EFCAB10 mRNA

NCBI chr 6:55,731,902...55,738,821
Ensembl chr 6:55,731,902...55,738,821

G

EF-hand domain containing 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of EFHC1 mRNA

NCBI chr 9:30,872,238...30,910,703
Ensembl chr 9:30,871,565...30,910,703

G

ephrin A1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of EFNA1 mRNA
Glyphosate results in increased expression of EFNA1 mRNA

PMID:28711546 PMID:31295307

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726

G

ephrin A2

decreases methylation

EXP

Glyphosate results in decreased methylation of EFNA2 gene

NCBI chr 7:10,167,091...10,177,719
Ensembl chr 7:10,167,091...10,177,719

G

ephrin A5

affects methylation

EXP

Glyphosate affects the methylation of EFNA5 gene

NCBI chr 9:109,763,786...110,042,396
Ensembl chr 9:109,767,252...110,042,348

G

ephrin B1

increases expression

EXP

Glyphosate results in increased expression of EFNB1 mRNA

NCBI chr X:68,297,529...68,310,335
Ensembl chr X:68,297,492...68,349,546

G

ephrin B3

decreases methylation

EXP

Glyphosate results in decreased methylation of EFNB3 gene

NCBI chr10:54,773,282...54,780,727
Ensembl chr10:54,773,282...54,797,651

G

epidermal growth factor receptor

decreases expression

ISO

Glyphosate results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

early growth response 1

multiple interactions
decreases expression

ISO

Glyphosate promotes the reaction [Estradiol results in decreased expression of EGR1 mRNA]
Glyphosate results in decreased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

ets homologous factor

affects methylation

EXP

Glyphosate affects the methylation of EHF gene

NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:110,096,756...110,134,928

G

euchromatic histone lysine methyltransferase 1

increases expression

EXP

Glyphosate results in increased expression of EHMT1 mRNA

NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349

G

euchromatic histone lysine methyltransferase 2

increases expression
increases methylation

EXP

Glyphosate results in increased expression of EHMT2 mRNA
Glyphosate results in increased methylation of EHMT2 gene

PMID:26302742 PMID:31011160

NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384

G

eukaryotic translation initiation factor 1A, X-linked

increases expression

ISO

Glyphosate results in increased expression of EIF1AX protein

NCBI chr X:39,307,320...39,322,023
Ensembl chr X:39,307,137...39,322,021

G

eukaryotic translation initiation factor 2 alpha kinase 1

decreases expression

EXP

Glyphosate results in decreased expression of EIF2AK1 mRNA

NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281

G

eukaryotic translation initiation factor 2 alpha kinase 3

affects methylation

EXP

Glyphosate affects the methylation of EIF2AK3 gene

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268

G

eukaryotic translation initiation factor 2 subunit alpha

decreases expression

EXP

Glyphosate results in decreased expression of EIF2S1 mRNA

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649

G

eukaryotic translation initiation factor 3, subunit A

decreases expression

ISO

Glyphosate results in decreased expression of EIF3A protein

NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025

G

eukaryotic translation initiation factor 3, subunit C

decreases expression

ISO

Glyphosate results in decreased expression of EIF3C protein

NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067

G

eukaryotic translation initiation factor 3, subunit F

decreases expression

ISO

Glyphosate results in decreased expression of EIF3F protein

NCBI chr 1:172,369,062...172,378,043
Ensembl chr 1:172,369,062...172,378,041

G

eukaryotic translation initiation factor 3, subunit M

decreases expression

ISO

Glyphosate results in decreased expression of EIF3M protein

NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193

G

eukaryotic translation initiation factor 4A1

increases expression

ISO

Glyphosate results in increased expression of EIF4A1 protein

NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602

G

eukaryotic translation initiation factor 4 gamma 1

increases expression

ISO

Glyphosate results in increased expression of EIF4G1 protein

NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367

G

eukaryotic translation initiation factor 5

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of EIF5 gene
Glyphosate results in decreased expression of EIF5 protein

PMID:35440735 PMID:37208198

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

eukaryotic translation initiation factor 5B

increases expression

ISO

Glyphosate results in increased expression of EIF5B mRNA

NCBI chr 9:47,718,706...47,773,289
Ensembl chr 9:47,718,706...47,778,583

G

endosome-lysosome associated apoptosis and autophagy regulator 1

affects methylation

EXP

Glyphosate affects the methylation of ELAPOR1 gene

NCBI chr 2:198,777,323...198,856,497
Ensembl chr 2:198,777,323...198,856,497

G

extracellular leucine-rich repeat and fibronectin type III domain containing 1

decreases methylation

EXP

Glyphosate results in decreased methylation of ELFN1 gene

NCBI chr12:19,773,911...19,839,375
Ensembl chr12:19,772,908...19,841,961

G

ETS transcription factor ELK4

decreases expression

ISO

Glyphosate results in decreased expression of ELK4 mRNA

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199

G

ER membrane protein complex subunit 7

decreases expression

EXP

Glyphosate results in decreased expression of EMC7 mRNA

NCBI chr 3:119,714,617...119,728,748
Ensembl chr 3:119,718,357...119,730,486

G

EMI domain containing 1

increases methylation

EXP

Glyphosate results in increased methylation of EMID1 gene

NCBI chr14:84,214,530...84,257,628
Ensembl chr14:84,214,530...84,257,579

G

elastin microfibril interfacer 1

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of EMILIN1 protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of EMILIN1 mRNA

PMID:33854195 PMID:37208198

NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657

G

elastin microfibril interfacer 2

increases expression

ISO

Glyphosate results in increased expression of EMILIN2 mRNA

NCBI chr 9:118,607,312...118,667,087
Ensembl chr 9:118,606,891...118,666,957

G

EMAP like 6

affects methylation

EXP

Glyphosate affects the methylation of EML6 gene

NCBI chr14:107,651,893...108,006,792
Ensembl chr14:107,699,400...108,005,409

G

endonuclease domain containing 1

increases expression

ISO

Glyphosate results in increased expression of ENDOD1 mRNA

NCBI chr 8:19,490,615...19,520,007
Ensembl chr 8:19,490,615...19,520,007

G

ecto-NOX disulfide-thiol exchanger 1

affects methylation

EXP

Glyphosate affects the methylation of ENOX1 gene

NCBI chr15:58,924,519...59,488,919
Ensembl chr15:59,215,018...59,488,918

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

increases methylation

EXP

Glyphosate results in increased methylation of ENPP1 gene

NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ENPP3 mRNA

NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314

G

ectonucleoside triphosphate diphosphohydrolase 3

increases expression

ISO

Glyphosate results in increased expression of ENTPD3 mRNA

NCBI chr 8:129,124,540...129,155,528
Ensembl chr 8:129,124,709...129,156,252

G

ectonucleoside triphosphate diphosphohydrolase 8

affects methylation

ISO

Glyphosate affects the methylation of ENTPD8 gene

NCBI chr 3:28,283,392...28,295,686
Ensembl chr 3:28,285,777...28,293,686

G

E1A binding protein p300

decreases expression

ISO

Glyphosate results in decreased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

E1A binding protein p400

affects methylation

EXP

Glyphosate affects the methylation of EP400 gene

NCBI chr12:51,551,665...51,658,635
Ensembl chr12:51,551,695...51,658,634

G

erythrocyte membrane protein band 4.1-like 2

increases expression

ISO

Glyphosate results in increased expression of EPB41L2 mRNA

NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105

G

erythrocyte membrane protein band 4.1-like 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of EPB41L3 gene

NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274

G

erythrocyte membrane protein band 4.1 like 4B

affects methylation

EXP

Glyphosate affects the methylation of EPB41L4B gene

NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752

G

ectopic P-granules 5 autophagy tethering factor

increases methylation

EXP

Glyphosate results in increased methylation of EPG5 gene

NCBI chr18:73,679,106...73,776,694
Ensembl chr18:73,679,116...73,776,677

G

Eph receptor A6

affects methylation

EXP

Glyphosate affects the methylation of EPHA6 gene

NCBI chr11:53,226,784...54,178,120
Ensembl chr11:53,226,954...54,166,987

G

Eph receptor B6

affects methylation

EXP

Glyphosate affects the methylation of EPHB6 gene

NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659

G

epoxide hydrolase 2

increases methylation
decreases expression

EXP
ISO

Glyphosate results in increased methylation of EPHX2 gene
Glyphosate results in decreased expression of EPHX2 protein

PMID:31011160 PMID:37208198

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

epoxide hydrolase 3

increases methylation
decreases expression

EXP

Glyphosate results in increased methylation of EPHX3 gene
Glyphosate results in decreased expression of EPHX3 mRNA

PMID:31011160 PMID:38314887

NCBI chr 7:11,857,367...11,862,674
Ensembl chr 7:11,857,367...11,862,674

G

EPM2A interacting protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of EPM2AIP1 mRNA

NCBI chr 8:120,112,265...120,119,613
Ensembl chr 8:120,112,084...120,121,458

G

erythropoietin

affects expression

ISO

Glyphosate affects the expression of EPO mRNA

NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

ISO

Glyphosate results in decreased expression of EPRS protein

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

epidermal growth factor receptor pathway substrate 15-like 1

affects methylation

EXP

Glyphosate affects the methylation of EPS15L1 gene

NCBI chr16:17,460,330...17,573,824
Ensembl chr16:17,460,465...17,535,703

G

epithelial stromal interaction 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of EPSTI1 mRNA

NCBI chr15:59,692,712...59,791,376
Ensembl chr15:59,693,142...59,791,380

G

ERCC excision repair 5, endonuclease

increases expression

ISO

Glyphosate results in increased expression of ERCC5 mRNA

NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084

G

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

decreases expression
affects methylation

ISO

Glyphosate results in decreased expression of ERCC8 mRNA
Glyphosate affects the methylation of ERCC8 promoter

PMID:31295307 PMID:35377194

NCBI chr 2:41,380,901...41,418,294
Ensembl chr 2:41,380,901...41,418,294

G

Ets2 repressor factor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ERF mRNA

NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213

G

ERGIC and golgi 2

decreases expression

EXP

Glyphosate results in decreased expression of ERGIC2 mRNA

NCBI chr 4:182,822,225...182,858,392
Ensembl chr 4:182,822,225...182,854,490

G

endoplasmic reticulum metallopeptidase 1

increases expression

ISO

Glyphosate results in increased expression of ERMP1 mRNA

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197

G

endoplasmic reticulum to nucleus signaling 1

increases expression

ISO

Glyphosate results in increased expression of ERN1 mRNA

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791

G

ERBB receptor feedback inhibitor 1

increases expression

ISO

Glyphosate results in increased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

esterase D

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ESD mRNA
Glyphosate results in increased expression of ESD protein

PMID:33854195 PMID:37208198

NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508

G

extra spindle pole bodies like 1, separase

decreases expression

ISO

Glyphosate results in decreased expression of ESPL1 mRNA

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570

G

estrogen receptor 1

increases expression
affects splicing
increases methylation
decreases methylation
affects expression
increases activity
increases response to substance
decreases expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of ESR1 mRNA; Glyphosate results in increased expression of ESR1 mRNA alternative form; Glyphosate results in increased expression of ESR1 protein
Glyphosate affects the splicing of ESR1 mRNA
Glyphosate results in increased methylation of ESR1 promoter
Glyphosate results in decreased methylation of ESR1 promoter
Glyphosate affects the expression of ESR1 mRNA
Glyphosate results in increased activity of ESR1 protein
Glyphosate affects the expression of ESR1 protein
Glyphosate results in increased expression of ESR1 mRNA; Glyphosate results in increased expression of ESR1 protein
ESR1 protein results in increased susceptibility to Glyphosate
Glyphosate results in decreased expression of ESR1 mRNA; Glyphosate results in decreased expression of ESR1 protein
[Glyphosate results in increased methylation of ESR1 promoter] which affects the splicing of ESR1 mRNA; Fulvestrant inhibits the reaction [Glyphosate results in increased expression of ESR1 protein]
[afimoxifene results in decreased susceptibility to Glyphosate] which results in increased expression of ESR1 protein modified form; [Glyphosate co-treated with Herbicides] results in decreased activity of ESR1 protein; [Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which affects the methylation of ESR1 promoter; afimoxifene inhibits the reaction [Glyphosate results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [Glyphosate results in increased activity of ESR1 protein]

PMID:19539684 PMID:23756170 PMID:27287056 PMID:27463640 PMID:27486271 More...

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen receptor 2

affects expression
multiple interactions
increases expression

ISO
EXP

Glyphosate affects the expression of ESR2 mRNA
[Glyphosate co-treated with Herbicides] results in decreased activity of ESR2 protein
Glyphosate results in increased expression of ESR2 mRNA; Glyphosate results in increased expression of ESR2 protein

PMID:19539684 PMID:23756170 PMID:27463640 PMID:34906888 PMID:35457321

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709

G

estrogen-related receptor gamma

increases methylation

EXP

Glyphosate results in increased methylation of ESRRG gene

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877

G

eukaryotic translation termination factor 1

decreases expression

ISO

Glyphosate results in decreased expression of ETF1 protein

NCBI chr18:26,776,518...26,804,857
Ensembl chr18:26,777,858...26,804,613

G

ETHE1, persulfide dioxygenase

decreases expression

ISO

Glyphosate results in decreased expression of ETHE1 protein

NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998

G

enhancer trap locus 4

affects methylation

EXP

Glyphosate affects the methylation of ETL4 gene

NCBI chr17:87,749,486...88,213,158
Ensembl chr17:87,403,819...88,213,158

G

ETS proto-oncogene 2, transcription factor

increases expression

ISO

Glyphosate results in increased expression of ETS2 mRNA

NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842

G

EWS RNA-binding protein 1

decreases expression

ISO

Glyphosate results in decreased expression of EWSR1 mRNA

NCBI chr14:84,179,413...84,208,149
Ensembl chr14:84,179,618...84,208,095

G

exonuclease 1

decreases expression

ISO

Glyphosate results in decreased expression of EXO1 mRNA

NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861

G

exocyst complex component 4

affects methylation

EXP

Glyphosate affects the methylation of EXOC4 gene

NCBI chr 4:62,774,896...63,551,541
Ensembl chr 4:62,774,935...63,552,943

G

exocyst complex component 6B

increases expression

ISO

Glyphosate results in increased expression of EXOC6B mRNA

NCBI chr 4:118,652,279...119,107,725
Ensembl chr 4:118,652,279...119,107,683

G

EYA transcriptional coactivator and phosphatase 2

affects methylation

EXP

Glyphosate affects the methylation of EYA2 gene

NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034

G

EYA transcriptional coactivator and phosphatase 3

affects methylation

EXP

Glyphosate affects the methylation of EYA3 gene

NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852

G

coagulation factor XIII A1 chain

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of F13A1 mRNA

NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948

G

coagulation factor XIII B chain

increases expression

ISO

Glyphosate results in increased expression of F13B mRNA

NCBI chr13:53,681,639...53,707,114
Ensembl chr13:53,681,622...53,707,300

G

coagulation factor III, tissue factor

increases expression

ISO

Glyphosate results in increased expression of F3 mRNA

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

coagulation factor V

decreases expression

EXP

Glyphosate results in decreased expression of F5 mRNA

NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247

G

coagulation factor VIII

increases expression

ISO

Glyphosate results in increased expression of F8 mRNA

NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683

G

fatty acid binding protein 1

increases expression

ISO

Glyphosate results in increased expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113

G

family with sequence similarity 110, member B

affects methylation

EXP

Glyphosate affects the methylation of FAM110B gene

NCBI chr 5:23,587,093...23,727,188
Ensembl chr 5:23,586,867...23,799,583

G

family with sequence similarity 114, member A1

affects methylation

EXP

Glyphosate affects the methylation of FAM114A1 gene

NCBI chr14:43,629,349...43,699,800
Ensembl chr14:43,629,375...43,699,800

G

family with sequence similarity 120 member C

affects methylation

EXP

Glyphosate affects the methylation of FAM120C gene

NCBI chr X:23,765,089...23,922,059
Ensembl chr X:23,766,976...23,920,840

G

family with sequence similarity 135, member A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA

NCBI chr 9:33,916,449...33,997,140
Ensembl chr 9:33,916,449...33,997,051

G

family with sequence similarity 151, member B

increases methylation

EXP

Glyphosate results in increased methylation of FAM151B gene

NCBI chr 2:25,409,382...25,446,225
Ensembl chr 2:25,409,383...25,445,466

G

family with sequence similarity 162, member A

decreases expression

ISO

Glyphosate results in decreased expression of FAM162A mRNA

NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560

G

family with sequence similarity 171, member A1

decreases methylation

EXP

Glyphosate results in decreased methylation of FAM171A1 gene

NCBI chr17:79,933,742...80,057,495
Ensembl chr17:79,934,050...80,057,495

G

family with sequence similarity 177, member A1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM177A1 gene

NCBI chr 6:78,367,780...78,382,703
Ensembl chr 6:78,367,780...78,392,836

G

family with sequence similarity 184, member B

increases methylation

EXP

Glyphosate results in increased methylation of FAM184B gene

NCBI chr14:69,688,031...69,803,922
Ensembl chr14:69,688,031...69,803,922

G

family with sequence similarity 204, member A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM204A mRNA

NCBI chr 1:269,323,473...269,352,772
Ensembl chr 1:269,323,473...269,352,772

G

family with sequence similarity 241 member A

decreases expression

EXP

Glyphosate results in decreased expression of FAM241A mRNA

NCBI chr 2:219,019,025...219,049,648
Ensembl chr 2:219,018,241...219,049,770

G

family with sequence similarity 241 member B

decreases expression

ISO

Glyphosate results in decreased expression of FAM241B mRNA

NCBI chr20:30,595,082...30,598,007
Ensembl chr20:30,595,084...30,597,844
Ensembl chr 6:30,595,084...30,597,844

G

FAM3 metabolism regulating signaling molecule C

affects methylation

EXP

Glyphosate affects the methylation of FAM3C gene

NCBI chr 4:51,805,686...51,853,030
Ensembl chr 4:51,805,703...51,853,030

G

family with sequence similarity 53, member A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM53A gene

NCBI chr14:81,308,127...81,348,930
Ensembl chr14:81,319,375...81,348,923

G

family with sequence similarity 9, member C

affects methylation

EXP

Glyphosate affects the methylation of FAM9B gene

NCBI chr X:151,278,579...151,297,455
Ensembl chr X:151,278,197...151,297,454

G

fatty acyl CoA reductase 2

increases methylation

EXP

Glyphosate results in increased methylation of FAR2 gene

NCBI chr 4:182,705,499...182,819,290
Ensembl chr 4:182,705,381...182,825,279

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases methylation

EXP

Glyphosate results in decreased methylation of FARP1 gene

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

Fas cell surface death receptor

increases expression

ISO

Glyphosate results in increased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

Fas ligand

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FASL mRNA

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503

G

fatty acid synthase

increases expression

ISO

Glyphosate results in increased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

FAT atypical cadherin 1

affects methylation

EXP

Glyphosate affects the methylation of FAT1 gene

NCBI chr16:53,909,759...54,029,175
Ensembl chr16:53,909,556...54,028,609

G

FAT atypical cadherin 3

multiple interactions
increases methylation

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FAT3 mRNA
Glyphosate results in increased methylation of FAT3 gene

PMID:31011160 PMID:37567420

NCBI chr 8:20,972,840...21,555,679
Ensembl chr 8:20,972,840...21,555,240

G

fibulin 7

decreases expression

EXP

Glyphosate results in decreased expression of FBLN7 mRNA

NCBI chr 3:136,564,825...136,601,205
Ensembl chr 3:136,564,917...136,601,198

G

fibrillin 1

increases expression

ISO

Glyphosate results in increased expression of FBN1 protein

NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283

G

fructose-bisphosphatase 1

increases expression

ISO

Glyphosate results in increased expression of FBP1 mRNA; Glyphosate results in increased expression of FBP1 protein

NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746

G

F-box and leucine-rich repeat protein 14, pseudogene 2

increases expression

EXP

Glyphosate results in increased expression of FBXL14-PS2 mRNA

NCBI chr13:51,271,967...51,273,868

G

F-box and leucine-rich repeat protein 17

decreases methylation
affects methylation

EXP

Glyphosate results in decreased methylation of FBXL17 gene
Glyphosate affects the methylation of FBXL17 gene

PMID:31011160 PMID:35440735

NCBI chr 9:110,227,609...110,666,184
Ensembl chr 9:110,227,609...110,653,980

G

F-box protein 6

decreases expression

ISO

Glyphosate results in decreased expression of FBXO6 mRNA

NCBI chr 5:163,859,909...163,865,693
Ensembl chr 5:163,859,916...163,865,574

G

F-box and WD repeat domain containing 8

affects methylation

EXP

Glyphosate affects the methylation of FBXW8 gene

NCBI chr12:44,087,375...44,177,985
Ensembl chr12:44,087,375...44,177,985

G

Fc gamma receptor 3A

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FCGR4 mRNA

NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651

G

ficolin A

decreases expression

EXP

Glyphosate results in decreased expression of FCNA mRNA

NCBI chr 3:28,844,036...28,847,441
Ensembl chr 3:28,844,039...28,847,237

G

Fc receptor-like A

decreases methylation

EXP

Glyphosate results in decreased methylation of FCRLA gene

NCBI chr13:85,693,177...85,702,875
Ensembl chr13:85,693,122...85,703,176

G

Fc receptor-like B

decreases methylation
decreases expression

EXP

Glyphosate results in decreased methylation of FCRLB gene
Glyphosate results in decreased expression of FCRLB mRNA

PMID:31011160 PMID:38314887

NCBI chr13:85,681,403...85,689,880
Ensembl chr13:85,682,472...85,688,707

G

fem-1 homolog B

affects methylation

EXP

Glyphosate affects the methylation of FEM1B gene

NCBI chr 8:72,160,722...72,173,996
Ensembl chr 8:72,160,722...72,173,996

G

flap structure-specific endonuclease 1

decreases expression

ISO

Glyphosate results in decreased expression of FEN1 mRNA

NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016

G

FER tyrosine kinase

affects methylation

EXP

Glyphosate affects the methylation of FER gene

NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:110,967,390...111,274,315

G

fibrinogen alpha chain

increases expression

ISO

Glyphosate results in increased expression of FGA mRNA

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

FYVE, RhoGEF and PH domain containing 5

increases expression

ISO

Glyphosate results in increased expression of FGD5 protein

NCBI chr 4:126,054,201...126,151,698
Ensembl chr 4:126,054,210...126,151,697

G

fibroblast growth factor 1

decreases expression

EXP

Glyphosate results in decreased expression of FGF1 mRNA

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 13

increases expression

ISO

Glyphosate results in increased expression of FGF13 mRNA

NCBI chr X:142,312,381...142,838,581
Ensembl chr X:142,312,391...142,423,536

G

fibroblast growth factor 7

increases expression

EXP

Glyphosate results in increased expression of FGF7 mRNA

NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328

G

FGFR1 oncogene partner 2

affects expression

ISO

Glyphosate affects the expression of FGFR1OP2 mRNA

NCBI chr 4:181,222,298...181,243,318
Ensembl chr 4:181,222,323...181,243,322

G

fibrinogen gamma chain

increases expression

ISO

Glyphosate results in increased expression of FGG mRNA

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

four and a half LIM domains 2

decreases expression

EXP

Glyphosate results in decreased expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326

G

formin homology 2 domain containing 3

affects methylation

EXP

Glyphosate affects the methylation of FHOD3 gene

NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508

G

fibrinogen C domain containing 1

decreases expression

ISO

Glyphosate results in decreased expression of FIBCD1 mRNA

NCBI chr 3:35,490,459...35,524,142
Ensembl chr 3:35,490,459...35,524,142

G

fin bud initiation factor homolog

increases expression

ISO

Glyphosate results in increased expression of FIBIN mRNA

NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479

G

FIC domain protein adenylyltransferase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FICD mRNA

NCBI chr12:48,549,737...48,554,626
Ensembl chr12:48,549,737...48,554,626

G

fidgetin-like 1

increases expression

EXP

Glyphosate results in increased expression of FIGNL1 mRNA

NCBI chr14:90,573,090...90,595,342
Ensembl chr14:90,581,771...90,592,316

G

FKBP prolyl isomerase 4

multiple interactions
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FKBP4 mRNA
Glyphosate results in decreased expression of FKBP4 protein

PMID:33854195 PMID:37208198

NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918

G

FKBP prolyl isomerase 5

decreases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of FKBP5 protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of FKBP5 gene

PMID:33854195 PMID:37208198

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118

G

filamin A

decreases expression

ISO

Glyphosate results in decreased expression of FLNA mRNA

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

filamin B

decreases expression

ISO

Glyphosate results in decreased expression of FLNB mRNA

NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209

G

Fms related receptor tyrosine kinase 1

increases expression

EXP

Glyphosate results in increased expression of FLT1 mRNA

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

formin 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FMN1 mRNA

NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124

G

flavin containing dimethylaniline monoxygenase 1

decreases expression
affects methylation

ISO
EXP

Glyphosate results in decreased expression of FMO1 protein
Glyphosate affects the methylation of FMO1 gene
Glyphosate results in decreased expression of FMO1 mRNA

PMID:26302742 PMID:35440735 PMID:36173347

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

ISO

Glyphosate results in decreased expression of FMO3 mRNA

NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256

G

fibronectin 1

decreases expression

ISO

Glyphosate results in decreased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

folliculin interacting protein 2

increases methylation

EXP

Glyphosate results in increased methylation of FNIP2 gene

NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:166,897,075...167,006,055

G

folate receptor alpha

decreases expression

EXP

Glyphosate results in decreased expression of FOLR1 mRNA

NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669

G

folate receptor beta

decreases expression

EXP

Glyphosate results in decreased expression of FOLR2 mRNA

NCBI chr 1:165,612,047...165,630,382
Ensembl chr 1:165,612,063...165,617,731

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression
increases expression

ISO
EXP

Glyphosate results in decreased expression of FOS mRNA
Glyphosate results in increased expression of FOS mRNA

PMID:31295307 PMID:35489704 PMID:35897073 PMID:38314887

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

forkhead box B1

decreases expression

ISO

Glyphosate results in decreased expression of FOXB1 mRNA

NCBI chr 8:79,288,161...79,290,781
Ensembl chr 8:79,287,616...79,291,490

G

forkhead box C2

increases expression

EXP

Glyphosate results in increased expression of FOXC2 mRNA

NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977

G

forkhead box I1

increases expression

ISO

Glyphosate results in increased expression of FOXI1 mRNA

NCBI chr10:19,310,466...19,314,405
Ensembl chr10:19,310,482...19,314,405

G

forkhead box N3

increases expression

ISO

Glyphosate results in increased expression of FOXN3 mRNA

NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040

G

forkhead box O1

increases expression

ISO

Glyphosate results in increased expression of FOXO1 mRNA

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419

G

forkhead box O3

increases expression

ISO

Glyphosate results in increased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

Fraser extracellular matrix complex subunit 1

decreases methylation

EXP

Glyphosate results in decreased methylation of FRAS1 gene

NCBI chr14:13,095,370...13,506,895
Ensembl chr14:13,095,370...13,504,664

G

FERM domain containing 4B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FRMD4B mRNA

NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287

G

FERM and PDZ domain containing 2

decreases expression

EXP

Glyphosate results in decreased expression of FRMPD2 mRNA

NCBI chr16:8,763,889...8,883,558
Ensembl chr16:8,763,956...8,883,551

G

FRY microtubule binding protein

decreases methylation

EXP

Glyphosate results in decreased methylation of FRY gene

NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603

G

FRY like transcription coactivator

increases methylation

EXP

Glyphosate results in increased methylation of FRYL gene

NCBI chr14:35,307,225...35,545,199
Ensembl chr14:35,310,656...35,545,147

G

fibrinogen silencer binding protein

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FSBP mRNA

NCBI chr 5:29,855,340...29,861,613
Ensembl chr 5:29,855,304...29,901,964

G

follicle stimulating hormone subunit beta

increases expression

ISO
EXP

Glyphosate results in increased expression of FSHB mRNA

PMID:22120950 PMID:30245445

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

follicle stimulating hormone receptor

decreases expression

ISO

Glyphosate results in decreased expression of FSHR mRNA

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288

G

follistatin-like 1

increases expression

ISO

Glyphosate results in increased expression of FSTL1 mRNA

NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126

G

follistatin-like 4

affects methylation

EXP

Glyphosate affects the methylation of FSTL4 gene

NCBI chr10:37,412,288...37,845,405
Ensembl chr10:37,412,288...37,845,393

G

Fus RNA binding protein

decreases expression

ISO

Glyphosate results in decreased expression of FUS mRNA

NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884

G

fucosyltransferase 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FUT2 mRNA

NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:105,255,390...105,276,647

G

fucosyltransferase 8

affects methylation

EXP

Glyphosate affects the methylation of FUT8 gene

NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:101,683,007...101,909,775

G

FYN binding protein 2

decreases expression

EXP

Glyphosate results in decreased expression of FYB2 mRNA

NCBI chr 5:124,906,005...125,029,867
Ensembl chr 5:124,905,982...125,029,865

G

frizzled class receptor 3

decreases expression

ISO

Glyphosate results in decreased expression of FZD3 mRNA

NCBI chr15:43,596,962...43,664,047
Ensembl chr15:43,596,965...43,663,960

G

frizzled class receptor 4

decreases expression

ISO

Glyphosate results in decreased expression of FZD4 mRNA

NCBI chr 1:152,692,507...152,701,372
Ensembl chr 1:152,692,507...152,701,372

G

frizzled class receptor 6

decreases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of FZD6 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FZD6 mRNA

PMID:31295307 PMID:33854195

NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680

G

G3BP stress granule assembly factor 1

decreases expression

ISO

Glyphosate results in decreased expression of G3BP1 protein

NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931

G

glucose 6 phosphatase catalytic subunit 3

decreases expression

ISO

Glyphosate results in decreased expression of G6PC3 mRNA

NCBI chr10:87,647,149...87,651,385
Ensembl chr10:87,647,062...87,653,453

G

glucose-6-phosphate dehydrogenase

decreases activity
increases activity

EXP

Glyphosate results in decreased activity of G6PD protein
Glyphosate results in increased activity of G6PD protein

PMID:23820267 PMID:24636977 PMID:28627408

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

GRB2-associated binding protein 2

increases expression

ISO

Glyphosate results in increased expression of GAB2 mRNA

NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:160,841,066...161,036,940

G

gamma-aminobutyric acid type B receptor subunit 1

increases expression

EXP

Glyphosate results in increased expression of GABBR1 mRNA

NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607

G

gamma-aminobutyric acid type A receptor subunit beta1

increases expression

ISO

Glyphosate results in increased expression of GABRB1 mRNA

NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,434,352...36,902,893

G

gamma-aminobutyric acid type A receptor subunit theta

increases expression

ISO

Glyphosate results in increased expression of GABRQ mRNA

NCBI chr X:155,737,838...155,755,225
Ensembl chr X:155,738,436...155,755,223

G

glutamate decarboxylase 1

affects binding

ISO

Glyphosate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Glyphosate binds to GAD1 protein

NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759

G

glutamate decarboxylase 2

affects binding

ISO

Glyphosate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Glyphosate binds to GAD2 protein

NCBI chr17:89,671,718...89,734,246
Ensembl chr17:89,671,716...89,941,089

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO

Glyphosate results in increased expression of GADD45A mRNA

PMID:31295307 PMID:31874349

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, beta

increases expression

ISO

Glyphosate results in increased expression of GADD45B mRNA

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

growth arrest and DNA-damage-inducible, gamma

increases expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of GADD45G mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GADD45G mRNA

PMID:31295307 PMID:33854195 PMID:34850229

NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369

G

polypeptide N-acetylgalactosaminyltransferase 15

increases expression

EXP

Glyphosate results in increased expression of GALNT15 mRNA

NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285

G

polypeptide N-acetylgalactosaminyltransferase 18

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of GALNT18 gene
Glyphosate affects the methylation of GALNT18 gene

PMID:31011160 PMID:35440735

NCBI chr 1:175,027,832...175,338,883
Ensembl chr 1:175,027,839...175,338,883

G

polypeptide N-acetylgalactosaminyltransferase 5

increases expression

ISO

Glyphosate results in increased expression of GALNT5 mRNA

NCBI chr 3:62,982,465...63,028,724
Ensembl chr 3:62,982,465...63,028,724

G

polypeptide N-acetylgalactosaminyltransferase 6

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GALNT6 mRNA

NCBI chr 7:133,668,612...133,715,909
Ensembl chr 7:133,668,615...133,698,439

G

guanidinoacetate N-methyltransferase

decreases expression

ISO

Glyphosate results in decreased expression of GAMT protein

NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083

G

growth associated protein 43

decreases expression

ISO

Glyphosate results in decreased expression of GAP43 mRNA

NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797

G

Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 24

decreases expression

EXP

Glyphosate results in decreased expression of GAPDH-PS24 mRNA

NCBI chr 7:12,775,727...12,781,222

G

Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 97

decreases expression

EXP

Glyphosate results in decreased expression of GAPDH-PS97 mRNA

NCBI chr 3:118,800,193...118,801,343

G

GTPase activating Rap/RanGAP domain-like 3

affects methylation

EXP

Glyphosate affects the methylation of GARNL3 gene

NCBI chr 3:36,686,388...36,830,011
Ensembl chr 3:36,686,389...36,830,020

G

growth arrest specific 5

increases expression

EXP
ISO

Glyphosate results in increased expression of GAS5 mRNA

PMID:26302742 PMID:37047296

NCBI chr13:75,836,963...75,840,284

G

GATA binding protein 4

increases expression

ISO

Glyphosate results in increased expression of GATA4 mRNA

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609

G

glutamine amidotransferase class 1 domain containing 3A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GATD3A mRNA

NCBI chr20:10,514,459...10,522,556
Ensembl chr20:10,514,443...10,522,555

G

1,4-alpha-glucan branching enzyme 1

affects methylation

EXP

Glyphosate affects the methylation of GBE1 gene

NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638

G

guanylate binding protein 2

multiple interactions
decreases expression

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP2 mRNA
Glyphosate results in decreased expression of GBP2 protein

PMID:36173347 PMID:37567420

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810

G

guanylate binding protein 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP4 mRNA

NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120

G

guanylate binding protein 7

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP7 mRNA

NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:233,948,677...233,970,526

G

gastrulation brain homeobox 1

increases methylation

EXP

Glyphosate results in increased methylation of GBX1 gene

NCBI chr 4:11,538,402...11,564,931
Ensembl chr 4:11,538,402...11,564,931

G

GC, vitamin D binding protein

increases expression

ISO

Glyphosate results in increased expression of GC protein

NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673

G

glutaryl-CoA dehydrogenase

decreases expression

ISO

Glyphosate results in decreased expression of GCDH protein

NCBI chr19:40,168,038...40,174,536
Ensembl chr19:40,168,141...40,175,686

G

GTP cyclohydrolase 1

increases expression

ISO

Glyphosate results in increased expression of GCH1 mRNA

NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412

G

glutamate cysteine ligase, modifier subunit

decreases expression

ISO

Glyphosate results in decreased expression of GCLM protein

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

ganglioside-induced differentiation-associated protein 1-like 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GDAP1L1 mRNA

NCBI chr 3:172,529,523...172,549,128
Ensembl chr 3:172,509,564...172,549,125

G

growth differentiation factor 15

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022

G

glial cell derived neurotrophic factor

decreases expression

EXP

Glyphosate results in decreased expression of GDNF mRNA

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

glycerophosphodiester phosphodiesterase domain containing 5

affects methylation

EXP

Glyphosate affects the methylation of GDPD5 gene

NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:163,091,833...163,173,559

G

glial fibrillary acidic protein

increases expression

ISO

Glyphosate results in increased expression of GFAP mRNA; Glyphosate results in increased expression of GFAP protein

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

growth hormone inducible transmembrane protein

affects methylation

EXP

Glyphosate affects the methylation of GHITM gene

NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123

G

gypsy retrotransposon integrase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIN1 mRNA

NCBI chr 9:105,740,914...105,762,357
Ensembl chr 9:105,742,094...105,762,357

G

GIPC PDZ domain containing family, member 3

increases expression

EXP

Glyphosate results in increased expression of GIPC3 mRNA

NCBI chr 7:9,026,905...9,034,005
Ensembl chr 7:9,026,905...9,034,795

G

GIT ArfGAP 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIT2 mRNA

NCBI chr12:47,490,350...47,531,232
Ensembl chr12:47,490,369...47,533,250

G

gap junction protein, alpha 1

decreases expression
multiple interactions

EXP

Glyphosate results in decreased expression of GJA1 mRNA; Glyphosate results in decreased expression of GJA1 protein
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of GJA1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of GJA1 protein]

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689

G

gastrokine 1

increases methylation

EXP

Glyphosate results in increased methylation of GKN1 gene

NCBI chr 4:121,347,417...121,352,705
Ensembl chr 4:121,347,417...121,352,830

G

gastrokine 2

increases methylation

EXP

Glyphosate results in increased methylation of GKN2 gene

NCBI chr 4:121,335,642...121,381,680
Ensembl chr 4:121,375,594...121,381,678

G

gastrokine 3

increases methylation

EXP

Glyphosate results in increased methylation of GKN3 gene

NCBI chr 4:121,386,319...121,390,719
Ensembl chr 4:121,386,395...121,392,139

G

galactosidase, beta 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GLB1 mRNA

NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326

G

GLI pathogenesis-related 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GLIPR1 mRNA

NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:49,373,581...49,384,640

G

GLIPR1 like 1

decreases expression

EXP

Glyphosate results in decreased expression of GLIPR1L1 mRNA

NCBI chr 7:49,436,867...49,463,860
Ensembl chr 7:49,436,383...49,463,949

G

GLIS family zinc finger 3

increases methylation

EXP

Glyphosate results in increased methylation of GLIS3 gene

NCBI chr 1:235,389,567...235,809,416
Ensembl chr 1:235,392,651...235,809,221

G

glyoxalase domain containing 5

decreases expression

ISO

Glyphosate results in decreased expression of GLOD5 mRNA

NCBI chr X:17,145,936...17,160,733
Ensembl chr X:17,145,938...17,160,619

G

glucagon-like peptide 1 receptor

decreases expression

EXP

Glyphosate results in decreased expression of GLP1R mRNA

NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,973,352...9,011,654

G

glutaredoxin

increases expression

EXP

Glyphosate results in increased expression of GLRX mRNA

NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543

G

glutaredoxin 5

increases methylation

EXP

Glyphosate results in increased methylation of GLRX5 gene

NCBI chr 6:129,752,902...129,763,278
Ensembl chr 6:129,752,840...129,763,278

G

glycosyltransferase 8 domain containing 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GLT8D2 mRNA

NCBI chr 7:22,917,055...22,968,616
Ensembl chr 7:22,917,100...22,968,930

G

G protein subunit alpha 12

decreases expression

ISO

Glyphosate results in decreased expression of GNA12 mRNA

NCBI chr12:18,919,629...19,000,185
Ensembl chr12:18,919,629...19,000,185

G

G protein subunit alpha o1

increases methylation

EXP

Glyphosate results in increased methylation of GNAO1 gene

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437

G

G protein subunit beta 4

decreases expression
affects methylation

ISO
EXP

Glyphosate results in decreased expression of GNB4 mRNA
Glyphosate affects the methylation of GNB4 gene

PMID:31295307 PMID:35440735

NCBI chr 2:117,289,112...117,329,050
Ensembl chr 2:117,293,284...117,328,945

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

ISO

Glyphosate results in decreased expression of GNE protein

NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251

G

G protein subunit gamma 10

decreases expression

ISO

Glyphosate results in decreased expression of GNG10 mRNA

NCBI chr 5:78,651,167...78,658,060
Ensembl chr 5:78,651,167...78,658,059

G

glucosamine-6-phosphate deaminase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GNPDA2 mRNA

NCBI chr14:38,874,611...38,892,688
Ensembl chr14:38,874,647...38,892,683

G

gonadotropin releasing hormone 1

decreases expression

ISO

Glyphosate results in decreased expression of GNRH1 mRNA

NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977

G

glutamic-oxaloacetic transaminase 1

multiple interactions
increases expression

ISO

[Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which results in increased activity of GOT1 protein
Glyphosate results in increased expression of GOT1 protein

PMID:36856429 PMID:37208198

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycoprotein 2

decreases expression

ISO

Glyphosate results in decreased expression of GP2 mRNA

NCBI chr 1:183,228,395...183,243,954
Ensembl chr 1:183,228,395...183,243,954

G

glypican 5

decreases expression

EXP

Glyphosate results in decreased expression of GPC5 mRNA

NCBI chr15:98,614,499...100,051,285
Ensembl chr15:98,646,340...100,051,514

G

G protein-coupled estrogen receptor 1

increases expression

EXP

Glyphosate results in increased expression of GPER1 mRNA; Glyphosate results in increased expression of GPER1 protein

NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144

G

G protein-coupled receptor 101

affects methylation

EXP

Glyphosate affects the methylation of GPR101 gene

NCBI chr X:140,575,818...140,579,734
Ensembl chr X:140,572,068...140,580,369

G

G protein-coupled receptor 149

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of GPR149 mRNA
Glyphosate results in decreased expression of GPR149 mRNA

PMID:33713393 PMID:38314887

NCBI chr 2:149,059,333...149,130,798
Ensembl chr 2:149,059,336...149,130,785

G

G protein-coupled receptor 158

affects methylation

EXP

Glyphosate affects the methylation of GPR158 gene

NCBI chr17:88,685,879...89,152,659
Ensembl chr17:88,742,823...89,152,658

G

G protein-coupled receptor 161

increases methylation

EXP

Glyphosate results in increased methylation of GPR161 gene

NCBI chr13:80,111,271...80,156,517
Ensembl chr13:80,117,114...80,152,861

G

G protein-coupled receptor 20

affects methylation

EXP

Glyphosate affects the methylation of GPR20 gene

NCBI chr 7:107,490,419...107,500,993
Ensembl chr 7:107,490,713...107,500,966

G

G protein-coupled receptor 39

affects methylation

EXP

Glyphosate affects the methylation of GPR39 gene

NCBI chr13:39,667,908...39,879,944
Ensembl chr13:39,667,909...39,880,902

G

G-protein coupled receptor 88

increases expression

ISO
EXP

Glyphosate results in increased expression of GPR88 mRNA

PMID:33713393 PMID:38314887

NCBI chr 2:206,876,373...206,885,034
Ensembl chr 2:206,868,585...206,884,945

G

G protein-coupled receptor associated sorting protein family member 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA

NCBI chr X:103,639,366...103,644,561
Ensembl chr X:103,609,243...103,650,463

G

G protein-regulated inducer of neurite outgrowth 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GPRIN1 mRNA

NCBI chr17:9,869,009...9,881,958
Ensembl chr17:9,868,571...9,894,560

G

G protein regulated inducer of neurite outgrowth 2

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of GPRIN2 gene
Glyphosate results in increased expression of GPRIN2 mRNA

PMID:35440735 PMID:35897073

NCBI chr16:9,502,697...9,518,901
Ensembl chr16:9,502,711...9,513,259

G

glutamic--pyruvic transaminase

decreases activity
increases expression
multiple interactions
increases activity

EXP
ISO

Glyphosate results in decreased activity of GPT protein
Glyphosate results in increased expression of GPT protein
Acetylcysteine inhibits the reaction [Glyphosate results in increased activity of GPT protein]; Zinc inhibits the reaction [Glyphosate results in increased expression of GPT protein]
[Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which results in increased activity of GPT protein; [imidacloprid co-treated with fipronil co-treated with Glyphosate] results in increased activity of and results in increased secretion of GPT protein; Glyphosate results in increased activity of and results in increased secretion of GPT protein

PMID:24636977 PMID:25067936 PMID:33797725 PMID:35850439 PMID:36608876 More...

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 1

decreases expression
increases activity
multiple interactions
increases expression

EXP

Glyphosate results in decreased expression of GPX1 protein
Glyphosate results in increased activity of GPX1 protein
NOX1 protein affects the reaction [Glyphosate results in decreased expression of GPX1 protein]
Glyphosate results in increased expression of GPX1 mRNA

PMID:25403740 PMID:31226268 PMID:34906888

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione peroxidase 3

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of GPX3 mRNA
Melatonin inhibits the reaction [Glyphosate results in increased expression of GPX3 mRNA]

PMID:31352102 PMID:33159990

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405

G

GRAM domain containing 1A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GRAMD1A mRNA

NCBI chr 1:95,494,378...95,520,730
Ensembl chr 1:95,494,378...95,520,716

G

GRAM domain containing 1C

increases methylation

EXP

Glyphosate results in increased methylation of GRAMD1C gene

NCBI chr11:70,139,076...70,224,478
Ensembl chr11:70,139,184...70,224,478

G

GRAM domain containing 2B

affects methylation

EXP

Glyphosate affects the methylation of GRAMD2B gene

NCBI chr18:52,082,128...52,180,056
Ensembl chr18:52,082,029...52,180,054

G

GRB2-related adaptor protein 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GRAP2 mRNA

NCBI chr 7:113,997,356...114,071,073
Ensembl chr 7:113,997,307...114,075,367

G

growth factor receptor bound protein 2

decreases expression

ISO

Glyphosate results in decreased expression of GRB2 mRNA

NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138

G

growth regulating estrogen receptor binding 1

increases expression
decreases expression
decreases methylation

ISO
EXP

Glyphosate results in increased expression of GREB1 mRNA
Glyphosate results in decreased expression of GREB1 mRNA
Glyphosate results in decreased methylation of GREB1 gene

PMID:28711546 PMID:31011160 PMID:38314887

NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126

G

gremlin 2, DAN family BMP antagonist

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GREM2 mRNA

NCBI chr13:89,310,897...89,403,856
Ensembl chr13:89,310,662...89,404,312

G

glutamate ionotropic receptor AMPA type subunit 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GRIA1 gene

NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309

G

glutamate ionotropic receptor delta type subunit 2

affects methylation

EXP

Glyphosate affects the methylation of GRID2 gene

NCBI chr 4:93,745,165...95,222,354
Ensembl chr 4:93,745,277...95,219,868

G

glutamate ionotropic receptor kainate type subunit 2

affects methylation

EXP

Glyphosate affects the methylation of GRIK2 gene

NCBI chr20:53,717,564...54,415,283
Ensembl chr20:53,716,090...54,415,202

G

glutamate ionotropic receptor kainate type subunit 4

affects methylation

EXP

Glyphosate affects the methylation of GRIK4 gene

NCBI chr 8:51,802,045...52,228,751
Ensembl chr 8:51,802,058...52,102,063

G

glutamate ionotropic receptor NMDA type subunit 1

increases expression
decreases expression

ISO

Glyphosate results in increased expression of GRIN1 mRNA; Glyphosate results in increased expression of GRIN1 protein
Glyphosate results in decreased expression of GRIN1 mRNA

PMID:30907447 PMID:32067069 PMID:34748853

NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GRINA mRNA

NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042

G

G protein-coupled receptor kinase 3

decreases expression

ISO

Glyphosate results in decreased expression of GRK3 mRNA

NCBI chr12:49,285,228...49,395,803
Ensembl chr12:49,285,263...49,395,802

G

G protein-coupled receptor kinase 6

decreases methylation

EXP

Glyphosate results in decreased methylation of GRK6 gene

NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,182,160...9,197,954

G

gasdermin A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GSDMA gene

NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804

G

Gse1 coiled-coil protein

decreases methylation

EXP

Glyphosate results in decreased methylation of GSE1 gene

NCBI chr19:65,182,678...65,538,183
Ensembl chr19:65,446,263...65,538,176

G

glutathione-disulfide reductase

increases activity
decreases expression

EXP

Glyphosate results in increased activity of GSR protein
Glyphosate results in decreased expression of GSR mRNA

PMID:23820267 PMID:37328116

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase, C-terminal domain containing

increases methylation

EXP

Glyphosate results in increased methylation of GSTCD gene

NCBI chr 2:224,173,764...224,268,743
Ensembl chr 2:224,173,473...224,265,680

G

glutathione S-transferase kappa 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GSTK1 mRNA

NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927

G

glutathione S-transferase mu 1

multiple interactions
decreases expression

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of GSTM1 mRNA
Glyphosate results in decreased expression of GSTM1 protein

PMID:32800223 PMID:37208198

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase, mu 5

affects expression
increases expression

ISO

Glyphosate affects the expression of GSTM3 protein
Glyphosate results in increased expression of GSTM3 mRNA

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

glutathione S-transferase, theta 4

decreases expression

EXP

Glyphosate results in decreased expression of GSTT4 mRNA

NCBI chr20:12,834,613...12,841,730
Ensembl chr20:12,834,612...12,841,744

G

general transcription factor IIH subunit 2

decreases expression

ISO

Glyphosate results in decreased expression of GTF2H2C mRNA

NCBI chr 2:33,358,863...33,386,726
Ensembl chr 2:33,358,869...33,386,688

G

general transcription factor IIH subunit 3

decreases expression

ISO

Glyphosate results in decreased expression of GTF2H3 mRNA

NCBI chr12:37,669,995...37,687,505
Ensembl chr12:37,669,997...37,686,466

G

general transcription factor II I

affects methylation

EXP

Glyphosate affects the methylation of GTF2I gene

NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677

G

GTP binding protein 4

affects methylation

ISO

Glyphosate affects the methylation of GTPBP4 gene

NCBI chr17:65,997,472...66,019,530
Ensembl chr17:66,276,566...66,289,637

G

gametocyte specific factor 1-like

decreases expression

ISO

Glyphosate results in decreased expression of GTSF1L mRNA

NCBI chr 3:172,155,533...172,158,228
Ensembl chr 3:172,154,100...172,162,042

G

guanylate cyclase activator 1A

increases methylation

EXP

Glyphosate results in increased methylation of GUCA1A gene

NCBI chr 9:21,080,782...21,096,221
Ensembl chr 9:21,086,642...21,096,221

G

guanylate cyclase activator 1B

increases methylation

EXP

Glyphosate results in increased methylation of GUCA1B gene

NCBI chr 9:21,097,274...21,105,107
Ensembl chr 9:21,097,274...21,105,107

G

guanylate cyclase activator 2B

affects methylation

EXP

Glyphosate affects the methylation of GUCA2B gene

NCBI chr 5:138,532,160...138,534,210
Ensembl chr 5:138,532,178...138,534,235

G

guanylate cyclase 1 soluble subunit beta 1

decreases expression

ISO

Glyphosate results in decreased expression of GUCY1B1 mRNA

NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987

G

glycophorin A

increases expression

EXP

Glyphosate results in increased expression of GYPA mRNA

NCBI chr19:44,354,669...44,370,304
Ensembl chr19:44,354,706...44,370,291

G

glycogen synthase 1

decreases expression
increases methylation

ISO
EXP

Glyphosate results in decreased expression of GYS1 mRNA
Glyphosate results in increased methylation of GYS1 gene

PMID:31011160 PMID:31295307

NCBI chr 1:105,051,916...105,071,763
Ensembl chr 1:105,051,961...105,072,419

G

granzyme B

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GZMB mRNA

NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469

G

H19 imprinted maternally expressed transcript

decreases expression

EXP

Glyphosate results in decreased expression of H19 mRNA

NCBI chr 1:207,160,175...207,162,851

G

H1.0 linker histone

decreases expression

ISO

Glyphosate results in decreased expression of H1F0 protein

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006

G

H2A clustered histone 20

increases expression

ISO

Glyphosate results in increased expression of H2AC20 protein

NCBI chr 2:186,468,748...186,469,226

G

H2A clustered histone 21

increases expression

ISO

Glyphosate results in increased expression of H2AC21 protein

NCBI chr 2:186,468,224...186,468,657

G

H2A clustered histone 22

decreases expression

ISO

Glyphosate results in decreased expression of H2AC22 mRNA

NCBI chr17:41,812,378...41,812,875
Ensembl chr17:41,797,862...41,812,946

G

H2A.X variant histone

increases expression

ISO

Glyphosate results in increased expression of H2AX protein modified form

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

H2A.Z variant histone 1, pseudogene 2

affects methylation

EXP

Glyphosate affects the methylation of H2AZ1-PS2 gene

NCBI chr 6:12,116,545...12,116,943

G

H4 clustered histone 1

decreases expression

ISO

Glyphosate results in decreased expression of H4C1 mRNA

NCBI chr17:47,393,764...47,394,168
Ensembl chr17:47,393,603...47,453,972
Ensembl chr17:47,393,603...47,453,972
Ensembl chr 4:47,393,603...47,453,972
Ensembl chr17:47,393,603...47,453,972
Ensembl chr17:47,393,603...47,453,972

G

H4 clustered histone 8

decreases expression

ISO

Glyphosate results in decreased expression of H4C9 mRNA

NCBI chr17:47,176,246...47,180,690
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr 4:41,797,152...41,806,539

G

3-hydroxyacyl-CoA dehydratase 3

decreases expression

ISO

Glyphosate results in decreased expression of HACD3 protein

NCBI chr 8:74,396,441...74,433,700
Ensembl chr 8:74,396,442...74,433,700

G

hydroxyacyl-CoA dehydrogenase

increases methylation

EXP

Glyphosate results in increased methylation of HADH gene

NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

ISO

Glyphosate results in increased expression of HADHA mRNA; Glyphosate results in increased expression of HADHA protein

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

ISO

Glyphosate results in increased expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835

G

hydroxyacid oxidase 1

increases expression

ISO

Glyphosate results in increased expression of HAO1 mRNA

NCBI chr 3:142,102,873...142,281,527
Ensembl chr 3:142,224,612...142,281,494

G

hyaluronan and proteoglycan link protein 2

increases expression

ISO

Glyphosate results in increased expression of HAPLN2 mRNA

NCBI chr 2:175,786,767...175,794,515
Ensembl chr 2:175,789,009...175,794,438

G

HUWE1 associated protein modifying stress responses 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of HAPSTR2 gene

NCBI chr X:143,958,364...143,960,399
Ensembl chr X:143,958,032...143,960,240

G

histidyl-tRNA synthetase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HARS1 mRNA

NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712

G

HAUS augmin like complex subunit 6

increases expression

EXP

Glyphosate results in increased expression of HAUS6 mRNA

NCBI chr 5:106,162,526...106,201,503
Ensembl chr 5:106,162,526...106,199,072

G

hepatitis A virus cellular receptor 1

increases expression

EXP

Glyphosate results in increased expression of HAVCR1 mRNA; Glyphosate results in increased expression of HAVCR1 protein

PMID:24361898 PMID:37001608

NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268

G

hepatitis A virus cellular receptor 2

affects methylation

ISO

Glyphosate affects the methylation of HAVCR2 gene

NCBI chr10:31,383,801...31,415,334
Ensembl chr10:31,383,925...31,413,872

G

hemoglobin alpha, adult chain 1

increases expression

ISO

Glyphosate results in increased expression of HBA-A1 protein

NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603

G

hemoglobin, beta adult minor chain

increases expression

ISO

Glyphosate results in increased expression of HBB-B2 protein

NCBI chr 1:167,655,583...167,656,963

G

hydroxycarboxylic acid receptor 2

increases methylation

EXP

Glyphosate results in increased methylation of HCAR2 gene

NCBI chr12:38,387,163...38,389,149
Ensembl chr12:38,387,230...38,389,391

G

hypocretin neuropeptide precursor

decreases expression

EXP

Glyphosate results in decreased expression of HCRT mRNA

NCBI chr10:86,190,289...86,191,524
Ensembl chr10:86,189,775...86,191,524

G

hypocretin receptor 1

decreases expression

EXP

Glyphosate results in decreased expression of HCRTR1 mRNA

NCBI chr 5:147,761,392...147,771,846
Ensembl chr 5:147,760,145...147,770,850

G

hypocretin receptor 2

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of HCRTR2 gene
Glyphosate results in increased expression of HCRTR2 mRNA

PMID:35440735 PMID:35897073

NCBI chr 8:85,870,279...85,986,405
Ensembl chr 8:85,870,279...85,986,405

G

histone deacetylase 1

decreases expression

ISO

Glyphosate results in decreased expression of HDAC1 mRNA

NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387

G

histone deacetylase 3

increases expression

ISO

Glyphosate results in increased expression of HDAC3 mRNA

NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025

G

histone deacetylase 9

affects methylation

EXP

Glyphosate affects the methylation of HDAC9 gene

NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:56,490,988...57,351,835

G

histidine decarboxylase

affects binding

ISO

Glyphosate binds to [HDC protein binds to Pyridoxal Phosphate]; Glyphosate binds to HDC protein

NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711

G

heme binding protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HEBP1 mRNA

NCBI chr 4:169,705,665...169,735,199
Ensembl chr 4:169,705,668...169,735,199

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

affects methylation

EXP

Glyphosate affects the methylation of HECW1 gene

NCBI chr17:55,366,904...55,780,028
Ensembl chr17:55,366,657...55,776,212

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

affects methylation

EXP

Glyphosate affects the methylation of HECW2 gene

NCBI chr 9:62,853,904...63,247,472
Ensembl chr 9:62,859,645...63,074,758

G

hes family bHLH transcription factor 1

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HES1 mRNA
Glyphosate results in increased expression of HES1 mRNA

PMID:31295307 PMID:33854195 PMID:35485992

NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061

G

hes family bHLH transcription factor 5

increases expression

ISO

Glyphosate results in increased expression of HES5 mRNA

NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021

G

hexosaminidase subunit beta

decreases expression

EXP

Glyphosate results in decreased expression of HEXB mRNA

NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771

G

hepatocyte growth factor

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of HGF mRNA
Glyphosate results in increased expression of HGF mRNA

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

hedgehog acyltransferase

increases methylation

EXP

Glyphosate results in increased methylation of HHAT gene

NCBI chr13:106,558,635...106,814,723
Ensembl chr13:106,541,866...106,811,563

G

3-hydroxyisobutyrate dehydrogenase

increases expression

ISO

Glyphosate results in increased expression of HIBADH protein

NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

ISO

Glyphosate results in increased expression of HIBCH protein

NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886

G

hypoxia inducible factor 1 subunit alpha

increases expression

EXP

Glyphosate results in increased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

hexokinase 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of HK3 mRNA

NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037

G

hexokinase domain containing 1

increases methylation

EXP

Glyphosate results in increased methylation of HKDC1 gene

NCBI chr20:30,878,037...30,917,044
Ensembl chr20:30,878,319...30,916,704

G

holocarboxylase synthetase

affects methylation

EXP

Glyphosate affects the methylation of HLCS gene

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

histocompatibility minor 13

affects methylation

ISO

Glyphosate affects the methylation of HM13 gene

NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:161,606,052...161,644,805

G

homeobox containing 1

increases expression

EXP

Glyphosate results in increased expression of HMBOX1 mRNA

NCBI chr15:43,243,503...43,376,011
Ensembl chr15:43,222,470...43,376,011

G

high mobility group box 1

decreases expression

ISO

Glyphosate results in decreased expression of HMGB1 mRNA

NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

ISO

Glyphosate results in increased expression of HMGCR mRNA

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

ISO

Glyphosate results in increased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression

ISO

Glyphosate results in increased expression of HMGCS2 mRNA

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242

G

high mobility group nucleosome binding domain 5

decreases expression
affects methylation

ISO
EXP

Glyphosate results in decreased expression of HMGN5 protein
Glyphosate affects the methylation of HMGN5 gene

PMID:35440735 PMID:36173347

NCBI chr X:78,161,439...78,170,613
Ensembl chr X:78,161,442...78,169,924

G

hyaluronan-mediated motility receptor

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of HMMR mRNA

NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390

G

heme oxygenase 1

increases expression

ISO

Glyphosate results in increased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heterogeneous nuclear ribonucleoprotein A1

decreases expression

ISO

Glyphosate results in decreased expression of HNRNPA1 protein

NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085

G

heterogeneous nuclear ribonucleoprotein F

increases expression

EXP

Glyphosate results in increased expression of HNRNPF mRNA

NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769

G

heterogeneous nuclear ribonucleoprotein K

increases expression

ISO

Glyphosate results in increased expression of HNRNPK protein

NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565

G

heterogeneous nuclear ribonucleoprotein L

increases expression
decreases expression

EXP
ISO

Glyphosate results in increased expression of HNRNPL mRNA
Glyphosate results in decreased expression of HNRNPL mRNA

PMID:26302742 PMID:35897073

NCBI chr 1:93,226,373...93,239,084
Ensembl chr 1:93,235,729...93,239,061

G

heterogeneous nuclear ribonucleoprotein M

affects expression

ISO

Glyphosate affects the expression of HNRNPM protein

NCBI chr 7:15,140,877...15,178,871
Ensembl chr 7:15,129,287...15,178,871

G

homer scaffold protein 2

increases methylation

EXP

Glyphosate results in increased methylation of HOMER2 gene

NCBI chr 1:144,968,207...145,069,022
Ensembl chr 1:144,976,436...145,068,997

G

homeobox A10

multiple interactions
decreases expression
increases expression

EXP

[Endosulfan co-treated with Glyphosate] results in increased expression of HOXA10 protein
Glyphosate results in decreased expression of HOXA10 mRNA
Glyphosate results in increased expression of HOXA10 protein

PMID:27287056 PMID:27486271 PMID:31550491 PMID:32640336

NCBI chr 4:82,662,204...82,671,490
Ensembl chr 4:82,662,204...82,665,922

G

homeo box B5

increases expression

EXP

Glyphosate results in increased expression of HOXB5 mRNA

NCBI chr10:81,765,911...81,768,119

G

homeo box D4

increases expression

EXP

Glyphosate results in increased expression of HOXD4 mRNA

NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948

G

hematopoietic prostaglandin D synthase

decreases expression

EXP

Glyphosate results in decreased expression of HPGDS mRNA

NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501

G

HPS1, biogenesis of lysosomal organelles complex 3 subunit 1

affects methylation

EXP

Glyphosate affects the methylation of HPS1 gene

NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739

G

hemopexin

decreases expression

ISO

Glyphosate results in decreased expression of HPX protein

NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156

G

hornerin

increases expression

ISO

Glyphosate results in increased expression of HRNR mRNA

NCBI chr 2:181,650,772...181,663,633

G

heparan sulfate-glucosamine 3-sulfotransferase 3B1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HS3ST3B1 mRNA

NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185

G

heparan sulfate-glucosamine 3-sulfotransferase 5

increases methylation

EXP

Glyphosate results in increased methylation of HS3ST5 gene

NCBI chr20:41,661,785...41,972,550
Ensembl chr20:41,773,601...41,972,542

G

heparan sulfate-glucosamine 3-sulfotransferase 6

affects methylation

EXP

Glyphosate affects the methylation of HS3ST6 gene

NCBI chr10:14,286,555...14,292,660
Ensembl chr10:14,286,507...14,292,660

G

heparan sulfate 6-O-sulfotransferase 3

decreases expression
increases methylation

ISO
EXP

Glyphosate results in decreased expression of HS6ST3 mRNA
Glyphosate results in increased methylation of HS6ST3 gene

PMID:31011160 PMID:35489704

NCBI chr15:102,688,420...103,407,725
Ensembl chr15:102,688,365...103,408,384

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA

NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812

G

hydroxysteroid (17-beta) dehydrogenase 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD17B10 mRNA

NCBI chr X:24,568,551...24,571,012
Ensembl chr X:24,568,551...24,574,681

G

hydroxysteroid (17-beta) dehydrogenase 13

decreases expression

ISO

Glyphosate results in decreased expression of HSD17B13 protein

NCBI chr14:6,056,708...6,071,463
Ensembl chr14:6,056,774...6,072,823

G

hydroxysteroid (17-beta) dehydrogenase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HSD17B2 mRNA

NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
increases expression

ISO
EXP

Glyphosate results in decreased expression of HSD3B1 mRNA
Glyphosate results in increased expression of HSD3B1 mRNA

PMID:10964798 PMID:37328116

NCBI chr 2:188,858,574...188,864,694

G

heat shock protein 90 alpha family class A member 1

decreases expression

ISO

Glyphosate results in decreased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein family A (Hsp70) member 12A

affects methylation

EXP

Glyphosate affects the methylation of HSPA12A gene

NCBI chr 1:267,921,780...268,083,171
Ensembl chr 1:267,921,782...268,082,794

G

heat shock protein family A (Hsp70) member 1A

increases expression

ISO

Glyphosate results in increased expression of HSPA1A mRNA

PMID:31295307 PMID:36625791

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1B

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of HSPA1B mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPA1B mRNA

PMID:31295307 PMID:33854195

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 4

decreases expression

ISO

Glyphosate results in decreased expression of HSPA4 protein

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835

G

heat shock protein family A (Hsp70) member 5

increases methylation

EXP

Glyphosate results in increased methylation of HSPA5 gene

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

ISO

Glyphosate results in increased expression of HSPA6 mRNA

NCBI chr13:85,805,911...85,807,052

G

heat shock protein family A (Hsp70) member 8

increases expression

ISO

Glyphosate results in increased expression of HSPA8 mRNA

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

HSPB1 associated protein 1

increases expression

ISO

Glyphosate results in increased expression of HSPBAP1 mRNA

NCBI chr11:78,445,376...78,500,034
Ensembl chr11:78,445,376...78,500,034

G

HSPA (Hsp70) binding protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPBP1 mRNA

NCBI chr 1:78,194,067...78,217,836
Ensembl chr 1:78,189,305...78,217,835

G

heparan sulfate proteoglycan 2

affects methylation

EXP

Glyphosate affects the methylation of HSPG2 gene

NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:154,960,846...155,061,971

G

HIV-1 Tat specific factor 1

affects methylation

EXP

Glyphosate affects the methylation of HTATSF1 gene

NCBI chr X:139,972,742...139,986,923
Ensembl chr X:139,972,742...139,986,923

G

5-hydroxytryptamine receptor 4

affects methylation

EXP

Glyphosate affects the methylation of HTR4 gene

NCBI chr18:58,036,277...58,221,327
Ensembl chr18:58,036,277...58,219,622

G

5-hydroxytryptamine receptor 7

decreases expression

EXP

Glyphosate results in decreased expression of HTR7 mRNA

NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230

G

hyaluronidase 1

increases methylation

EXP

Glyphosate results in increased methylation of HYAL1 gene

NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:117,129,277...117,133,146

G

hyaluronidase 3

increases methylation

EXP

Glyphosate results in increased methylation of HYAL3 gene

NCBI chr 8:117,133,028...117,138,663
Ensembl chr 8:117,132,649...117,139,289

G

hydroxylysine kinase

decreases expression

EXP

Glyphosate results in decreased expression of HYKK mRNA

NCBI chr 8:64,212,043...64,235,809
Ensembl chr 8:64,212,071...64,235,818

G

inhibitor of DNA binding 2

increases expression

ISO

Glyphosate results in increased expression of ID2 mRNA

NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961

G

inhibitor of DNA binding 3

decreases expression

ISO

Glyphosate results in decreased expression of ID3 mRNA

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856

G

isocitrate dehydrogenase (NADP(+)) 2

decreases expression

ISO

Glyphosate results in decreased expression of IDH2 protein

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of IDH3A protein

NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

decreases expression

EXP

Glyphosate results in decreased expression of IDH3B mRNA

NCBI chr 3:137,934,971...137,940,275
Ensembl chr 3:137,934,697...137,940,107

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

decreases expression

EXP

Glyphosate results in decreased expression of IDH3G mRNA

NCBI chr X:156,666,573...156,675,482
Ensembl chr X:156,666,577...156,675,799

G

immediate early response 2

decreases expression

ISO

Glyphosate results in decreased expression of IER2 mRNA

NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708

G

immediate early response 3

multiple interactions
increases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IER3 mRNA
Glyphosate results in increased expression of IER3 mRNA

PMID:33854195 PMID:34850229

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377

G

immediate early response 5

increases expression

ISO

Glyphosate results in increased expression of IER5 mRNA

NCBI chr13:69,820,450...69,822,542
Ensembl chr13:69,820,451...69,822,543

G

interferon, alpha-inducible protein 27 like 2A

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFI27L2A mRNA

NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:128,363,658...128,365,146

G

interferon-induced protein 44

decreases expression

ISO

Glyphosate results in decreased expression of IFI44 mRNA

NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877

G

interferon-induced protein with tetratricopeptide repeats 1

decreases expression
multiple interactions

ISO

Glyphosate results in decreased expression of IFIT1 mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT1 mRNA

PMID:35489704 PMID:37567420

NCBI chr 1:241,565,197...241,567,262
Ensembl chr 1:241,543,184...241,568,148

G

interferon-induced protein with tetratricopeptide repeats 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT2 mRNA

NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798

G

interferon-induced protein with tetratricopeptide repeats 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT3 mRNA

NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521

G

interferon alpha 12 like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IFNA12L gene

NCBI chr 5:108,592,149...108,593,214
Ensembl chr 5:108,541,882...108,571,940

G

interferon, alpha 4

increases expression

ISO

Glyphosate results in increased expression of IFNA4 mRNA

NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:108,115,064...108,116,010

G

interferon alpha and beta receptor subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of IFNAR1 mRNA

NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205

G

interferon alpha and beta receptor subunit 2

decreases expression

ISO

Glyphosate results in decreased expression of IFNAR2 mRNA

NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937

G

interferon gamma

increases expression

ISO

Glyphosate results in increased expression of IFNG mRNA
Glyphosate results in increased expression of IFNG protein

PMID:25172162 PMID:31874349

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon gamma receptor 1

decreases expression

ISO

Glyphosate results in decreased expression of IFNGR1 mRNA

NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437

G

interferon, lambda receptor 1

increases methylation

EXP

Glyphosate results in increased methylation of IFNLR1 gene

NCBI chr 5:153,203,597...153,225,911
Ensembl chr 5:153,203,597...153,225,911

G

interferon-related developmental regulator 2

increases methylation

EXP

Glyphosate results in increased methylation of IFRD2 gene

NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836

G

intraflagellar transport 22

decreases methylation

EXP

Glyphosate results in decreased methylation of IFT22 gene

NCBI chr12:25,397,092...25,405,522
Ensembl chr12:25,387,347...25,405,510

G

intraflagellar transport 43

affects methylation

EXP

Glyphosate affects the methylation of IFT43 gene

NCBI chr 6:111,460,689...111,537,224
Ensembl chr 6:111,456,476...111,537,224

G

insulin-like growth factor 1

increases expression

ISO

Glyphosate results in increased expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764

G

insulin-like growth factor binding protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IGFBP1 mRNA

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344

G

insulin-like growth factor binding protein 6

decreases expression

EXP

Glyphosate results in decreased expression of IGFBP6 mRNA

NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795

G

immunoglobulin kappa variable 2-112 like 2

multiple interactions
affects methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IGKV2-112L2 gene
Glyphosate affects the methylation of IGKV2-112L2 gene

PMID:33854195 PMID:35440735

NCBI chr 4:103,444,658...103,445,307
Ensembl chr 4:103,766,891...103,767,229

G

IgLON family member 5

decreases expression

ISO

Glyphosate results in decreased expression of IGLON5 mRNA

NCBI chr 1:103,017,985...103,035,512
Ensembl chr 1:103,018,518...103,035,870

G

immunoglobulin superfamily, member 11

decreases expression
increases methylation

EXP

Glyphosate results in decreased expression of IGSF11 mRNA
Glyphosate results in increased methylation of IGSF11 gene

PMID:26302742 PMID:31011160

NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425

G

IKAROS family zinc finger 3

decreases expression

EXP

Glyphosate results in decreased expression of IKZF3 mRNA

NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861

G

interleukin 10

increases expression

EXP
ISO

Glyphosate results in increased expression of IL10 mRNA
Glyphosate results in increased expression of IL10 protein

PMID:25172162 PMID:34953950

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 13

multiple interactions
increases expression

ISO

IL13 protein affects the reaction [Glyphosate results in increased expression of IL33 protein]; IL13 protein affects the reaction [Glyphosate results in increased expression of IL5 protein]; IL13 protein affects the reaction [Glyphosate results in increased expression of TSLP protein]
Glyphosate results in increased expression of IL13 protein

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483

G

interleukin 13 receptor subunit alpha 2

decreases expression

ISO

Glyphosate results in decreased expression of IL13RA2 mRNA

NCBI chr X:115,814,620...115,886,080
Ensembl chr X:115,814,622...115,841,455

G

interleukin 15

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of IL15 mRNA
Glyphosate results in increased expression of IL15 mRNA

NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348

G

interleukin 18 receptor accessory protein

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IL18RAP mRNA

NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:50,263,733...50,296,583

G

interleukin 1 beta

increases expression

ISO
EXP

Glyphosate results in increased expression of IL1B mRNA; Glyphosate results in increased expression of IL1B protein

PMID:32045792 PMID:36608876

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor type 2

increases expression

ISO

Glyphosate results in increased expression of IL1R2 mRNA

NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374

G

interleukin 1 receptor-like 1

increases expression

EXP

Glyphosate results in increased expression of IL1RL1 mRNA

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891

G

interleukin 22 receptor subunit alpha 2

decreases expression

ISO

Glyphosate results in decreased expression of IL22RA2 mRNA

NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950

G

interleukin 23 receptor

decreases expression

ISO

Glyphosate results in decreased expression of IL23R mRNA

NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:97,909,972...98,004,110

G

interleukin 27

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IL27 mRNA

NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:190,603,522...190,609,258

G

interleukin 33

multiple interactions
increases expression

ISO

IL13 protein affects the reaction [Glyphosate results in increased expression of IL33 protein]

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901

G

interleukin 4 receptor

decreases expression

ISO

Glyphosate results in decreased expression of IL4R mRNA

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636

G

interleukin 5

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of IL5 protein
IL13 protein affects the reaction [Glyphosate results in increased expression of IL5 protein]

NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003

G

interleukin 6

increases expression
decreases expression

ISO

Glyphosate results in increased expression of IL6 mRNA
Glyphosate results in decreased expression of IL6 mRNA

PMID:31874349 PMID:37047296

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 receptor

decreases expression

ISO

Glyphosate results in decreased expression of IL6R mRNA

NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221

G

innate immunity activator

decreases methylation

EXP

Glyphosate results in decreased methylation of INAVA gene

NCBI chr13:50,218,149...50,238,430
Ensembl chr13:50,218,150...50,238,454

G

inhibin subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of INHA protein

NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009

G

inhibin subunit beta A

decreases expression

ISO

Glyphosate results in decreased expression of INHBA mRNA

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

inhibin subunit beta B

decreases expression

ISO

Glyphosate results in decreased expression of INHBB mRNA

NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609

G

INO80 complex subunit D

increases expression

EXP

Glyphosate results in increased expression of INO80D mRNA

NCBI chr 9:71,940,941...72,007,879
Ensembl chr 9:71,951,031...72,040,232

G

inositol polyphosphate-1-phosphatase

increases expression

ISO

Glyphosate results in increased expression of INPP1 mRNA

NCBI chr 9:56,161,816...56,209,774
Ensembl chr 9:56,161,852...56,234,569

G

inositol polyphosphate-5-phosphatase F

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of INPP5F mRNA

NCBI chr 1:192,620,891...192,700,681
Ensembl chr 1:192,620,891...192,700,681

G

insulin 2

increases expression

ISO

Glyphosate results in increased expression of INS mRNA

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805

G

inversin

decreases expression

ISO

Glyphosate results in decreased expression of INVS mRNA

NCBI chr 5:67,406,511...67,559,355
Ensembl chr 5:67,406,485...67,559,350

G

IQ motif containing B1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IQCB1 mRNA

NCBI chr11:77,410,986...77,465,540
Ensembl chr11:77,410,314...77,465,478

G

IQ motif containing H

decreases methylation

EXP

Glyphosate results in decreased methylation of IQCH gene

NCBI chr 8:72,784,932...72,978,632
Ensembl chr 8:72,787,756...72,978,598

G

IQ motif containing GTPase activating protein 2

increases methylation

EXP

Glyphosate results in increased methylation of IQGAP2 gene

NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649

G

interleukin-1 receptor-associated kinase 2

decreases methylation

EXP

Glyphosate results in decreased methylation of IRAK2 gene

NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210

G

interleukin-1 receptor-associated kinase 3

decreases expression

EXP

Glyphosate results in decreased expression of IRAK3 mRNA

NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706

G

interleukin-1 receptor-associated kinase 4

decreases methylation

EXP

Glyphosate results in decreased methylation of IRAK4 gene

NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:127,561,717...127,597,109

G

interferon regulatory factor 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRF1 mRNA

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947

G

interferon regulatory factor 2 binding protein 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IRF2BP2 mRNA

NCBI chr19:71,456,689...71,462,368
Ensembl chr19:71,456,689...71,462,368

G

interferon regulatory factor 4

increases expression

EXP

Glyphosate results in increased expression of IRF4 mRNA

NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730

G

interferon regulatory factor 7

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRF7 mRNA

NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023

G

interferon regulatory factor 9

decreases expression

ISO

Glyphosate results in decreased expression of IRF9 protein

NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879

G

immunity-related GTPase M

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of IRGM mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRGM1 mRNA

PMID:31874349 PMID:37567420

NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228

G

insulin receptor substrate 1

decreases expression

ISO

Glyphosate results in decreased expression of IRS1 mRNA

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538

G

insulin receptor substrate 2

increases expression

ISO

Glyphosate results in increased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543

G

insulin receptor substrate 4

increases expression

ISO

Glyphosate results in increased expression of IRS4 mRNA

NCBI chr X:110,132,490...110,148,473
Ensembl chr X:110,132,405...110,149,088

G

iroquois homeobox 4

decreases expression

EXP

Glyphosate results in decreased expression of IRX4 mRNA

NCBI chr 1:31,859,101...31,868,089
Ensembl chr 1:31,859,101...31,868,089

G

ISL LIM homeobox 1

increases expression

ISO

Glyphosate results in increased expression of ISL1 mRNA

NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442

G

ISY1 splicing factor homolog

increases expression

EXP

Glyphosate results in increased expression of ISY1 mRNA

NCBI chr 4:121,833,870...121,854,561
Ensembl chr 4:121,806,992...121,854,561

G

integrin subunit alpha 2

decreases expression

ISO

Glyphosate results in decreased expression of ITGA2 mRNA

NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509

G

integrin subunit alpha 3

decreases expression

ISO

Glyphosate results in decreased expression of ITGA3 mRNA

NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901

G

integrin subunit alpha 5

decreases expression

ISO

Glyphosate results in decreased expression of ITGA5 mRNA

NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305

G

integrin subunit alpha 9

decreases methylation

EXP

Glyphosate results in decreased methylation of ITGA9 gene

NCBI chr 8:127,185,244...127,493,296
Ensembl chr 8:127,169,226...127,493,296

G

integrin subunit alpha E

increases expression

ISO

Glyphosate results in increased expression of ITGAE mRNA

NCBI chr10:58,203,331...58,262,606
Ensembl chr10:58,203,364...58,262,606

G

integrin subunit alpha V

decreases expression

ISO

Glyphosate results in decreased expression of ITGAV mRNA

NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511

G

integrin subunit beta 1

decreases expression

ISO

Glyphosate results in decreased expression of ITGB1 mRNA

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269

G

integrin subunit beta 1 binding protein 2

increases expression

EXP

Glyphosate results in increased expression of ITGB1BP2 mRNA

NCBI chr X:70,612,118...70,617,158
Ensembl chr X:70,612,521...70,617,158

G

integrin subunit beta 5

decreases expression

ISO

Glyphosate results in decreased expression of ITGB5 mRNA

NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373

G

integrin subunit beta 6

decreases expression

ISO

Glyphosate results in decreased expression of ITGB6 mRNA

NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333

G

inositol-tetrakisphosphate 1-kinase

increases expression

ISO

Glyphosate results in increased expression of ITPK1 mRNA

NCBI chr 6:127,475,589...127,609,320
Ensembl chr 6:127,476,808...127,609,062

G

inositol 1,4,5-trisphosphate receptor, type 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of ITPR1 mRNA; Glyphosate results in decreased expression of ITPR1 protein alternative form
Glyphosate results in increased expression of ITPR1 mRNA

PMID:24073338 PMID:31295307

NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504

G

inositol 1,4,5-trisphosphate receptor, type 3

affects expression

ISO

Glyphosate affects the expression of ITPR3 mRNA

NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184

G

inositol 1,4,5-trisphosphate receptor interacting protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ITPRIP mRNA

NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:256,699,832...256,727,644

G

intersectin 1

increases expression

ISO

Glyphosate results in increased expression of ITSN1 mRNA

NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598

G

junctional sarcoplasmic reticulum protein 1

decreases methylation

EXP

Glyphosate results in decreased methylation of JSRP1 gene

NCBI chr 7:9,539,997...9,556,730
Ensembl chr 7:9,552,324...9,557,137

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Glyphosate results in increased expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

JunB proto-oncogene, AP-1 transcription factor subunit

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of JUNB mRNA

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Glyphosate results in increased expression of JUND mRNA

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148

G

kalirin, RhoGEF kinase

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of KALRN gene
Glyphosate affects the methylation of KALRN gene

PMID:31011160 PMID:35440735

NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329

G

KN motif and ankyrin repeat domains 4

increases expression

ISO

Glyphosate results in increased expression of KANK4 mRNA

NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002

G

katanin interacting protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KATNIP gene

NCBI chr 1:189,700,838...189,867,402
Ensembl chr 1:189,700,775...189,867,402

G

potassium voltage-gated channel subfamily A member 5

increases expression

EXP

Glyphosate results in increased expression of KCNA5 mRNA

NCBI chr 4:161,040,853...161,044,311
Ensembl chr 4:160,996,950...161,044,408

G

potassium voltage-gated channel subfamily A member 6

affects methylation

ISO

Glyphosate affects the methylation of KCNA6 promoter

NCBI chr 4:161,229,103...161,262,352
Ensembl chr 4:161,191,961...161,263,240

G

potassium voltage-gated channel subfamily D member 2

affects methylation

EXP

Glyphosate affects the methylation of KCND2 gene

NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522

G

potassium voltage-gated channel modifier subfamily G member 3

affects methylation

EXP

Glyphosate affects the methylation of KCNG3 gene

NCBI chr 6:16,803,842...16,851,791
Ensembl chr 6:16,803,665...16,851,791

G

potassium voltage-gated channel interacting protein 1

increases expression

ISO

Glyphosate results in increased expression of KCNIP1 mRNA

NCBI chr10:18,723,726...19,093,025
Ensembl chr10:18,723,726...19,093,087

G

potassium inwardly-rectifying channel, subfamily J, member 13

decreases expression

EXP

Glyphosate results in decreased expression of KCNJ13 mRNA

NCBI chr 9:95,509,228...95,528,400
Ensembl chr 9:95,510,877...95,520,817

G

potassium inwardly-rectifying channel, subfamily J, member 15

increases methylation

EXP

Glyphosate results in increased methylation of KCNJ15 gene

NCBI chr11:48,046,953...48,091,285
Ensembl chr11:48,035,655...48,092,457

G

potassium calcium-activated channel subfamily M regulatory beta subunit 4

decreases expression

ISO

Glyphosate results in decreased expression of KCNMB4 mRNA

NCBI chr 7:53,952,150...54,005,101
Ensembl chr 7:53,949,881...54,005,281

G

potassium voltage-gated channel, modifier subfamily S, member 3

increases expression

ISO

Glyphosate results in increased expression of KCNS3 mRNA

NCBI chr 6:39,527,410...39,584,105
Ensembl chr 6:39,523,777...39,618,848

G

potassium sodium-activated channel subfamily T member 2

increases expression

ISO

Glyphosate results in increased expression of KCNT2 mRNA

NCBI chr13:54,214,831...54,609,889
Ensembl chr13:54,215,307...54,607,924

G

kielin cysteine rich BMP regulator

affects methylation

ISO

Glyphosate affects the methylation of KCP gene

NCBI chr 4:59,048,209...59,083,522
Ensembl chr 4:59,047,968...59,083,531

G

potassium channel tetramerization domain containing 8

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KCTD8 mRNA

NCBI chr14:39,127,210...39,372,118
Ensembl chr14:39,127,379...39,372,078

G

lysine demethylase 5A

affects methylation

EXP

Glyphosate affects the methylation of KDM5A gene

NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121

G

kinase insert domain receptor

decreases expression
increases expression
multiple interactions

ISO

Glyphosate results in decreased expression of KDR mRNA
Glyphosate results in increased expression of KDR protein
afimoxifene inhibits the reaction [Glyphosate results in increased expression of KDR protein]

PMID:29890199 PMID:31295307

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192

G

Kelch-like ECH-associated protein 1

increases expression

ISO

Glyphosate results in increased expression of KEAP1 mRNA

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042

G

KH domain containing 3, subcortical maternal complex member

decreases expression

ISO

Glyphosate results in decreased expression of KHDC3 protein

NCBI chr 8:82,722,980...82,724,884
Ensembl chr 8:82,722,980...82,724,884

G

KH domain containing 4, pre-mRNA splicing factor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KHDC4 mRNA

NCBI chr 2:176,446,895...176,475,405
Ensembl chr 2:176,446,910...176,475,392

G

kinesin family member 12

increases methylation

EXP

Glyphosate results in increased methylation of KIF12 gene

NCBI chr 5:81,611,730...81,620,977
Ensembl chr 5:81,611,734...81,618,369

G

kinesin family member 13A

increases expression

ISO

Glyphosate results in increased expression of KIF13A mRNA

NCBI chr17:17,972,227...18,154,763
Ensembl chr17:17,972,325...18,154,760

G

kinesin family member 18A

increases expression

EXP

Glyphosate results in increased expression of KIF18A mRNA

NCBI chr 3:116,219,007...116,279,378
Ensembl chr 3:116,219,007...116,279,227

G

kinesin family member 27

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KIF27 mRNA

NCBI chr17:6,304,960...6,383,745
Ensembl chr17:6,304,989...6,375,182

G

kinesin family member 4A

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KIF4 mRNA

NCBI chr X:69,761,803...69,864,335
Ensembl chr X:69,761,883...69,864,335

G

KIT proto-oncogene receptor tyrosine kinase

increases expression
decreases expression

ISO

Glyphosate results in increased expression of KIT mRNA
Glyphosate results in decreased expression of KIT mRNA

PMID:30785197 PMID:31295307

NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812

G

Klotho

decreases expression

EXP

Glyphosate results in decreased expression of KL mRNA

NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015

G

KLF transcription factor 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KLF10 mRNA

NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948

G

KLF transcription factor 15

increases expression

ISO

Glyphosate results in increased expression of KLF15 mRNA

NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373

G

KLF transcription factor 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of KLF2 mRNA

NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768

G

KLF transcription factor 5

affects methylation

EXP

Glyphosate affects the methylation of KLF5 gene

NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262

G

kelch domain containing 7A

increases expression

ISO

Glyphosate results in increased expression of KLHDC7A mRNA

NCBI chr 5:157,501,740...157,507,843
Ensembl chr 5:157,485,191...157,507,954

G

kelch-like family member 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KLHL10 gene

NCBI chr10:85,876,804...85,893,081
Ensembl chr10:85,876,783...85,893,081

G

kelch-like family member 29

increases methylation

EXP

Glyphosate results in increased methylation of KLHL29 gene

NCBI chr 6:33,805,922...34,110,055
Ensembl chr 6:33,805,922...34,110,055

G

kelch-like family member 32

decreases expression

ISO

Glyphosate results in decreased expression of KLHL32 mRNA

NCBI chr 5:43,117,861...43,365,080
Ensembl chr 5:43,122,167...43,365,042

G

kelch-like family member 9

increases methylation

EXP

Glyphosate results in increased methylation of KLHL9 gene

NCBI chr 5:108,449,492...108,453,676
Ensembl chr 5:108,437,583...108,454,140

G

kallikrein 1

decreases expression

ISO

Glyphosate results in decreased expression of KLK1 mRNA

NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270

G

killer cell lectin like receptor B1A

affects methylation

EXP

Glyphosate affects the methylation of KLRB1 gene

NCBI chr 4:163,576,672...163,590,201
Ensembl chr 4:163,576,672...163,619,374

G

killer cell lectin like receptor G1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KLRG1 mRNA

NCBI chr 4:157,127,571...157,139,372
Ensembl chr 4:157,127,571...157,139,372

G

lysine methyltransferase 2A

affects methylation

EXP

Glyphosate affects the methylation of KMT2A gene

NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317

G

lysine methyltransferase 2B

increases expression

EXP

Glyphosate results in increased expression of KMT2B mRNA

NCBI chr 1:94,949,144...94,969,239
Ensembl chr 1:94,949,144...94,968,441

G

lysine methyltransferase 2D

increases expression

EXP

Glyphosate results in increased expression of KMT2D mRNA

NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:131,859,696...131,900,072

G

lysine methyltransferase 5C

increases expression

EXP

Glyphosate results in increased expression of KMT5C mRNA

NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:78,128,325...78,135,931

G

kinetochore scaffold 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KNL1 mRNA

NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774

G

kringle containing transmembrane protein 1

affects methylation

EXP

Glyphosate affects the methylation of KREMEN1 gene

NCBI chr14:84,295,931...84,361,534
Ensembl chr14:84,297,700...84,361,614

G

keratin 13

increases methylation

EXP

Glyphosate results in increased methylation of KRT13 gene

NCBI chr10:85,552,287...85,556,499
Ensembl chr10:85,552,287...85,556,499

G

keratin 17

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KRT17 mRNA

NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787

G

keratin 18

decreases expression

EXP

Glyphosate results in decreased expression of KRT18 mRNA

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

keratin 20

increases expression

ISO

Glyphosate results in increased expression of KRT20 mRNA

NCBI chr10:84,880,952...84,890,285
Ensembl chr10:84,880,952...84,890,285

G

keratin 24

decreases expression

EXP

Glyphosate results in decreased expression of KRT24 mRNA

NCBI chr10:84,728,350...84,733,486
Ensembl chr10:84,728,350...84,733,486

G

keratin 26

decreases expression

EXP

Glyphosate results in decreased expression of KRT26 mRNA

NCBI chr10:84,777,137...84,791,756
Ensembl chr10:84,777,897...84,787,001

G

keratin 4

increases expression

ISO

Glyphosate results in increased expression of KRT4 mRNA

NCBI chr 7:134,924,753...134,931,050
Ensembl chr 7:134,924,753...134,930,713

G

keratin 7

increases expression

ISO

Glyphosate results in increased expression of KRT7 protein

NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786

G

keratin 78

affects expression

ISO

Glyphosate affects the expression of KRT78 protein

NCBI chr 7:134,952,877...134,960,727
Ensembl chr 7:134,953,043...134,960,220

G

keratin 8

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of KRT8 protein
Glyphosate results in decreased expression of KRT8 mRNA

PMID:37208198 PMID:38314887

NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403

G

keratinocyte associated protein 3

increases expression

EXP

Glyphosate results in increased expression of KRTCAP3 mRNA

NCBI chr 6:30,840,906...30,842,500
Ensembl chr 6:30,840,906...30,842,475

G

kinase suppressor of ras 2

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of KSR2 gene
Glyphosate results in increased methylation of KSR2 gene

PMID:31011160 PMID:35440735

NCBI chr12:44,462,579...44,848,555
Ensembl chr12:44,471,038...44,848,308

G

laminin subunit alpha 3

affects methylation

EXP

Glyphosate affects the methylation of LAMA3 gene

NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449

G

laminin subunit beta 1

affects methylation

EXP

Glyphosate affects the methylation of LAMB1 gene

NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:53,563,073...53,630,760

G

laminin subunit beta 2

increases expression

ISO

Glyphosate results in increased expression of LAMB2 protein

NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090

G

laminin subunit gamma 1

increases expression

ISO

Glyphosate results in increased expression of LAMC1 protein

NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986

G

laminin subunit gamma 3

decreases methylation

EXP

Glyphosate results in decreased methylation of LAMC3 gene

NCBI chr 3:35,562,989...35,624,460
Ensembl chr 3:35,562,713...35,624,460

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

increases expression

ISO

Glyphosate results in increased expression of LAMTOR3 mRNA

NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:229,084,858...229,099,383

G

LanC like glutathione S-transferase 1

decreases expression

EXP

Glyphosate results in decreased expression of LANCL1 mRNA

NCBI chr 9:75,968,284...75,998,397
Ensembl chr 9:75,968,286...76,003,475

G

LanC like family member 3

increases expression

ISO

Glyphosate results in increased expression of LANCL3 mRNA

NCBI chr X:16,150,991...16,282,425
Ensembl chr X:16,150,991...16,282,425

G

LARGE xylosyl- and glucuronyltransferase 1

affects methylation

EXP

Glyphosate affects the methylation of LARGE1 gene

NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,609,004...12,054,707

G

lactase

decreases expression

ISO

Glyphosate results in decreased expression of LCT mRNA

NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872

G

lactate dehydrogenase A

increases expression

ISO

Glyphosate results in increased expression of LDHA mRNA; Glyphosate results in increased expression of LDHA protein

PMID:36572786 PMID:36608876

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

lactate dehydrogenase A-like 6B

decreases expression

ISO

Glyphosate results in decreased expression of LDHAL6B mRNA

NCBI chr 1:48,402,997...48,404,420
Ensembl chr 1:48,403,012...48,404,851

G

low density lipoprotein receptor adaptor protein 1

affects methylation

EXP

Glyphosate affects the methylation of LDLRAP1 gene

NCBI chr 5:152,239,296...152,262,290
Ensembl chr 5:152,229,505...152,262,290

G

LDOC1, regulator of NFKB signaling

affects methylation

EXP

Glyphosate affects the methylation of LDOC1 gene

NCBI chr X:144,837,879...145,110,607
Ensembl chr X:144,837,865...145,111,017

G

leptin receptor

decreases expression

ISO

Glyphosate results in decreased expression of LEPR mRNA

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

galectin 3 binding protein

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of LGALS3BP mRNA

NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848

G

galectin-like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LGALSL mRNA

NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487

G

leucine rich repeat containing G protein coupled receptor 5

affects methylation

EXP

Glyphosate affects the methylation of LGR5 gene

NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163

G

luteinizing hormone subunit beta

increases expression
increases methylation

EXP
ISO

Glyphosate results in increased expression of LHB mRNA; Glyphosate results in increased expression of LHB protein
Glyphosate results in increased methylation of LHB gene

PMID:22120950 PMID:30245445 PMID:31011160

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

LIM homeobox 1

decreases expression

ISO

Glyphosate results in decreased expression of LHX1 mRNA

NCBI chr10:69,894,288...69,901,076
Ensembl chr10:69,894,288...69,901,076

G

LIM homeobox 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of LHX2 gene

NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645

G

LIM homeobox 9

decreases expression

EXP

Glyphosate results in decreased expression of LHX9 mRNA

NCBI chr13:52,941,207...52,961,436
Ensembl chr13:52,941,210...52,962,266

G

ligand of ATE1

decreases expression

EXP

Glyphosate results in decreased expression of LIAT1 mRNA

NCBI chr10:61,370,698...61,374,438
Ensembl chr10:61,370,766...61,374,436

G

LIF, interleukin 6 family cytokine

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of LIF mRNA
Glyphosate results in increased expression of LIF mRNA

PMID:31295307 PMID:32640336

NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053

G

LIF receptor subunit alpha

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of LIFR mRNA
Glyphosate results in increased expression of LIFR mRNA

PMID:31295307 PMID:35897073

NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364

G

DNA ligase 3

increases expression

ISO

Glyphosate results in increased expression of LIG3 mRNA

NCBI chr10:68,215,371...68,238,705
Ensembl chr10:68,215,407...68,238,704

G

LIM and calponin homology domains 1

decreases methylation

EXP

Glyphosate results in decreased methylation of LIMCH1 gene

NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,466,433...41,778,837

G

LIM domain kinase 1

increases expression

ISO

Glyphosate results in increased expression of LIMK1 mRNA

NCBI chr12:27,663,177...27,697,085
Ensembl chr12:27,663,018...27,697,209

G

leucine rich repeat and Ig domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of LINGO1 gene

NCBI chr 8:65,907,275...66,089,485
Ensembl chr 8:65,897,844...66,091,740

G

lipase E, hormone sensitive type

increases expression

ISO

Glyphosate results in increased expression of LIPE mRNA

NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117

G

lipase H

decreases expression

ISO

Glyphosate results in decreased expression of LIPH mRNA

NCBI chr11:92,536,724...92,586,117
Ensembl chr11:92,537,860...92,586,120

G

lipase I

affects methylation
decreases methylation

EXP

Glyphosate affects the methylation of LIPI gene
Glyphosate results in decreased methylation of LIPI gene

PMID:31011160 PMID:35440735

NCBI chr11:27,676,354...27,716,025
Ensembl chr11:27,676,354...27,716,018

G

lipase, member O1

decreases expression

EXP

Glyphosate results in decreased expression of LIPO1 mRNA

NCBI chr 1:240,724,517...240,738,417
Ensembl chr 1:240,725,581...240,737,160

G

lipopolysaccharide-induced TNF factor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LITAF mRNA

NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930

G

lipase maturation factor 2

increases methylation

EXP

Glyphosate results in increased methylation of LMF2 gene

NCBI chr 7:122,297,971...122,302,423
Ensembl chr 7:122,297,973...122,302,423

G

lamin B1

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of LMNB1 gene
Glyphosate results in decreased expression of LMNB1 mRNA

PMID:31295307 PMID:35440735

NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283

G

ligand of numb-protein X 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LNX2 mRNA

NCBI chr12:13,119,139...13,184,401
Ensembl chr12:13,119,139...13,184,401

G

zinc finger protein 2-like

increases expression

ISO

Glyphosate results in increased expression of ZFP661 mRNA

NCBI chr 3:135,247,385...135,271,682
Ensembl chr 3:135,263,010...135,274,567

G

U6 spliceosomal RNA

decreases expression

ISO

Glyphosate results in decreased expression of RNU6-611P mRNA

NCBI chr 3:169,186,502...169,186,608
Ensembl chr 3:169,186,502...169,186,608

G

U4 spliceosomal RNA

increases expression

ISO

Glyphosate results in increased expression of RNU4-60P mRNA

NCBI chr 4:54,412,826...54,412,909
Ensembl chr 4:54,412,770...54,412,909

G

Y-linked testis-specific protein 1-like

increases methylation

EXP

Glyphosate results in increased methylation of SSTY1 gene

NCBI chr Y:45,100,812...45,103,070

G

lysyl oxidase-like 2

increases expression

EXP

Glyphosate results in increased expression of LOXL2 mRNA

NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842

G

lysyl oxidase-like 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LOXL3 gene

NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046

G

lysophosphatidic acid receptor 3

increases methylation
increases expression
decreases expression

EXP
ISO

Glyphosate results in increased methylation of LPAR3 gene
Glyphosate results in increased expression of LPAR3 mRNA
Glyphosate results in decreased expression of LPAR3 mRNA

PMID:31011160 PMID:31295307

NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197

G

lysophosphatidylcholine acyltransferase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPCAT1 gene

NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:31,594,622...31,644,946

G

lysophosphatidylglycerol acyltransferase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPGAT1 gene

NCBI chr13:105,825,630...105,896,366
Ensembl chr13:105,820,468...105,896,364

G

lipin 1

increases expression

ISO

Glyphosate results in increased expression of LPIN1 mRNA

NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991

G

lipin 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LPIN3 mRNA

NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:169,960,522...169,978,031

G

lactoperoxidase

decreases expression

ISO

Glyphosate results in decreased expression of LPO mRNA

NCBI chr10:73,104,170...73,124,683
Ensembl chr10:73,104,188...73,123,456

G

lecithin retinol acyltransferase

increases expression

ISO

Glyphosate results in increased expression of LRAT mRNA

NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148

G

leucine rich repeat and fibronectin type III domain containing 3

decreases methylation

EXP

Glyphosate results in decreased methylation of LRFN3 gene

NCBI chr 1:94,744,315...94,751,001
Ensembl chr 1:94,744,321...94,751,178

G

leucine-rich alpha-2-glycoprotein 1

decreases expression

EXP

Glyphosate results in decreased expression of LRG1 mRNA

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337

G

LDL receptor related protein 1B

affects methylation

EXP

Glyphosate affects the methylation of LRP1B gene

NCBI chr 3:45,004,001...47,125,147
Ensembl chr 3:45,004,689...45,957,692

G

LDL receptor related protein 6

decreases expression

ISO

Glyphosate results in decreased expression of LRP6 mRNA

NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716

G

leucine rich repeat containing 34

decreases expression

EXP

Glyphosate results in decreased expression of LRRC34 mRNA

NCBI chr 2:114,680,787...114,702,961
Ensembl chr 2:114,680,094...114,702,961

G

leucine rich repeat containing 4C

affects methylation

EXP

Glyphosate affects the methylation of LRRC4C gene

NCBI chr 3:102,760,152...104,139,222
Ensembl chr 3:103,970,485...104,146,212

G

leucine rich repeat containing 61

increases expression

ISO

Glyphosate results in increased expression of LRRC61 mRNA

NCBI chr 4:78,834,783...78,854,810
Ensembl chr 4:78,833,857...78,868,931

G

leucine rich repeat containing 75B

increases methylation

EXP

Glyphosate results in increased methylation of LRRC75B gene

NCBI chr20:13,099,741...13,105,942
Ensembl chr20:13,094,809...13,109,532

G

leucine rich repeat containing 8 VRAC subunit A

increases expression

ISO

Glyphosate results in increased expression of LRRC8A mRNA

NCBI chr 3:33,902,299...33,934,989
Ensembl chr 3:33,908,268...33,933,625

G

leucine rich repeat transmembrane neuronal 4

increases expression

ISO

Glyphosate results in increased expression of LRRTM4 mRNA

NCBI chr 4:114,103,783...114,894,696
Ensembl chr 4:114,103,870...114,109,726

G

leucine-rich single-pass membrane protein 2

increases methylation

EXP

Glyphosate results in increased methylation of LSMEM2 gene

NCBI chr 8:117,144,498...117,149,300
Ensembl chr 8:117,144,464...117,149,185

G

leukocyte specific transcript 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of LST1 mRNA

NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,639,341...3,642,669

G

leukotriene A4 hydrolase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LTA4H mRNA

NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641

G

latent transforming growth factor beta binding protein 1

decreases methylation
decreases expression

EXP
ISO

Glyphosate results in decreased methylation of LTBP1 gene
Glyphosate results in decreased expression of LTBP1 mRNA

PMID:31011160 PMID:31295307

NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036

G

LUC7 pre-mRNA splicing factor like 3

increases expression

EXP

Glyphosate results in increased expression of LUC7L3 mRNA

NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429

G

leucine rich adaptor protein 1-like

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LURAP1L gene

NCBI chr 5:100,402,921...100,455,479
Ensembl chr 5:100,407,483...100,455,478

G

leucine zipper protein 1

increases expression

ISO

Glyphosate results in increased expression of LUZP1 mRNA

NCBI chr 5:153,989,570...154,065,071
Ensembl chr 5:153,987,683...154,070,438

G

lymphocyte antigen 6 family member G6D

increases methylation

EXP

Glyphosate results in increased methylation of LY6G6D gene

NCBI chr20:3,746,630...3,757,036
Ensembl chr20:3,742,116...3,757,193

G

lymphocyte antigen 6 family member G6E

increases methylation

EXP

Glyphosate results in increased methylation of LY6G6E gene

NCBI chr20:3,749,352...3,752,578
Ensembl chr20:3,749,656...3,751,392

G

lymphocyte antigen 6 family member G6F

increases methylation

EXP

Glyphosate results in increased methylation of LY6G6F gene

NCBI chr20:3,742,116...3,746,984
Ensembl chr20:3,742,116...3,757,193

G

LYN proto-oncogene, Src family tyrosine kinase

affects methylation

EXP

Glyphosate affects the methylation of LYN gene

NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:21,437,084...21,554,461

G

Ly6/Plaur domain containing 2

decreases expression

EXP

Glyphosate results in decreased expression of LYPD2 mRNA

NCBI chr 7:108,506,545...108,508,582
Ensembl chr 7:108,506,545...108,508,582

G

Ly6/Plaur domain containing 6

decreases expression

ISO

Glyphosate results in decreased expression of LYPD6 mRNA

NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:54,896,575...55,041,929

G

microtubule-actin crosslinking factor 1

affects methylation

EXP

Glyphosate affects the methylation of MACF1 gene

NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890

G

macoilin 1

increases expression

ISO

Glyphosate results in increased expression of MACO1 mRNA

NCBI chr 5:152,296,107...152,358,684
Ensembl chr 5:152,296,558...152,358,684

G

mono-ADP ribosylhydrolase 1

increases expression

ISO

Glyphosate results in increased expression of MACROD1 protein

NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348

G

MAF bZIP transcription factor A

decreases expression

EXP

Glyphosate results in decreased expression of MAFA mRNA

NCBI chr 7:109,313,021...109,315,813
Ensembl chr 7:109,313,121...109,315,760

G

MAF bZIP transcription factor F

increases expression

ISO

Glyphosate results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

MAF bZIP transcription factor K

increases expression

ISO

Glyphosate results in increased expression of MAFK mRNA

NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192

G

MAGE family member L2

increases expression

ISO

Glyphosate results in increased expression of MAGEL2 mRNA

NCBI chr 1:125,292,033...125,296,575
Ensembl chr 1:125,292,033...125,296,575

G

MAM and LDL receptor class A domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of MALRD1 gene

NCBI chr17:83,327,372...84,039,558
Ensembl chr17:83,327,372...84,039,559

G

mastermind-like transcriptional coactivator 1

decreases expression

ISO

Glyphosate results in decreased expression of MAML1 mRNA

NCBI chr10:35,089,715...35,124,100
Ensembl chr10:35,089,715...35,124,100

G

mannosidase, alpha, class 1C, member 1

affects methylation

EXP

Glyphosate affects the methylation of MAN1C1 gene

NCBI chr 5:152,057,839...152,197,737
Ensembl chr 5:152,057,967...152,197,138

G

mannosidase beta

increases methylation

EXP

Glyphosate results in increased methylation of MANBA gene

NCBI chr 2:226,583,968...226,676,520
Ensembl chr 2:226,583,917...226,676,517

G

microtubule-associated protein 1B

increases methylation

EXP

Glyphosate results in increased methylation of MAP1B gene

NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094

G

microtubule-associated protein 1 light chain 3 alpha

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of MAP1LC3A mRNA
Glyphosate results in increased lipidation of and results in increased localization of MAP1LC3A protein

PMID:31352102 PMID:33159990

NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850

G

microtubule-associated protein 2

increases expression

ISO

Glyphosate results in increased expression of MAP2 mRNA; Glyphosate results in increased expression of MAP2 protein

NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459

G

mitogen activated protein kinase kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of MAP2K1 mRNA

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184

G

mitogen activated protein kinase kinase 3

increases expression
decreases expression

ISO

Glyphosate results in increased expression of MAP2K3 mRNA
Glyphosate results in decreased expression of MAP2K3 mRNA

NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004

G

mitogen activated protein kinase kinase 4

affects methylation
decreases expression

ISO

Glyphosate affects the methylation of MAP2K4 gene
Glyphosate results in decreased expression of MAP2K4 mRNA

PMID:31295307 PMID:35377194

NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185

G

mitogen-activated protein kinase kinase 6

decreases expression

ISO

Glyphosate results in decreased expression of MAP2K6 mRNA

NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721

G

mitogen-activated protein kinase kinase kinase 13

decreases expression

ISO

Glyphosate results in decreased expression of MAP3K13 mRNA

NCBI chr11:92,596,436...92,741,717
Ensembl chr11:92,601,738...92,739,663

G

mitogen-activated protein kinase kinase kinase 19

decreases expression

EXP

Glyphosate results in decreased expression of MAP3K19 mRNA

NCBI chr13:41,852,633...41,896,078
Ensembl chr13:41,852,531...41,895,565

G

mitogen activated protein kinase kinase kinase 3

decreases expression

ISO

Glyphosate results in decreased expression of MAP3K3 mRNA

NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651

G

mitogen activated protein kinase kinase kinase 4

affects methylation

EXP

Glyphosate affects the methylation of MAP3K4 gene

NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117

G

mitogen-activated protein kinase kinase kinase kinase 3

decreases expression

ISO

Glyphosate results in decreased expression of MAP4K3 mRNA

NCBI chr 6:20,029,246...20,198,583
Ensembl chr 6:20,029,397...20,198,583

G

MAP7 domain containing 3

decreases expression

EXP

Glyphosate results in decreased expression of MAP7D3 mRNA

NCBI chr X:139,656,587...139,723,239
Ensembl chr X:139,656,587...139,723,251

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

EXP
ISO

Glyphosate results in increased phosphorylation of MAPK1 protein
afimoxifene inhibits the reaction [Glyphosate results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Glyphosate results in increased phosphorylation of MAPK1 protein]

PMID:28627408 PMID:29890199

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 10

increases methylation

EXP

Glyphosate results in increased methylation of MAPK10 gene

NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100

G

mitogen activated protein kinase 13

decreases expression

ISO

Glyphosate results in decreased expression of MAPK13 mRNA

NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191

G

mitogen activated protein kinase 3

multiple interactions
increases expression
increases phosphorylation

ISO
EXP

afimoxifene inhibits the reaction [Glyphosate results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Glyphosate results in increased phosphorylation of MAPK3 protein]
Glyphosate results in increased expression of MAPK3 mRNA

PMID:28627408 PMID:29890199 PMID:31295307 PMID:32045792

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

increases expression

ISO

Glyphosate results in increased expression of MAPK8 mRNA

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 8 interacting protein 3

increases expression

ISO
EXP

Glyphosate results in increased expression of MAPK8IP3 mRNA

PMID:26302742 PMID:31295307

NCBI chr10:14,422,936...14,463,387
Ensembl chr10:14,422,936...14,462,812

G

MAPK activated protein kinase 2

multiple interactions
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MAPKAPK2 mRNA
Glyphosate results in decreased expression of MAPKAPK2 mRNA

PMID:31295307 PMID:33854195

NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326

G

MAPK activated protein kinase 3

affects methylation

EXP

Glyphosate affects the methylation of MAPKAPK3 gene

NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228

G

membrane associated ring-CH-type finger 8

increases expression

ISO

Glyphosate results in increased expression of MARCHF8 mRNA

NCBI chr 4:151,086,076...151,203,205
Ensembl chr 4:151,088,506...151,203,205

G

meiosis regulator and mRNA stability factor 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MARF1 mRNA

NCBI chr10:1,395,271...1,439,974
Ensembl chr10:1,395,282...1,439,974

G

microtubule affinity regulating kinase 1

affects methylation

EXP

Glyphosate affects the methylation of MARK1 gene

NCBI chr13:98,981,727...99,086,998
Ensembl chr13:98,983,020...99,086,701

G

MAS1 proto-oncogene, G protein-coupled receptor

decreases expression

ISO

Glyphosate results in decreased expression of MAS1 mRNA

NCBI chr 1:50,428,064...50,459,537
Ensembl chr 1:50,425,257...50,500,561

G

microtubule associated serine/threonine kinase family member 4

increases expression

ISO

Glyphosate results in increased expression of MAST4 mRNA

NCBI chr 2:35,627,190...36,219,090
Ensembl chr 2:35,627,190...36,218,832

G

methionine adenosyltransferase 2A

increases expression

ISO

Glyphosate results in increased expression of MAT2A mRNA

NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645

G

mitochondrial antiviral signaling protein

increases expression

ISO

Glyphosate results in increased expression of MAVS protein

NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:138,904,771...138,919,126

G

myoglobin

decreases expression

EXP

Glyphosate results in decreased expression of MB mRNA

NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958

G

methyl-CpG binding domain 4 DNA glycosylase

decreases expression

ISO

Glyphosate results in decreased expression of MBD4 mRNA

NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:150,565,655...150,577,578

G

mannose binding lectin 1

decreases expression

EXP

Glyphosate results in decreased expression of MBL1 mRNA

NCBI chr16:17,063,232...17,069,271
Ensembl chr16:17,060,703...17,069,271

G

muscleblind-like splicing regulator 1

affects methylation

EXP

Glyphosate affects the methylation of MBNL1 gene

NCBI chr 2:146,789,570...146,964,136
Ensembl chr 2:146,789,596...146,964,134

G

myelin basic protein

affects methylation

EXP

Glyphosate affects the methylation of MBP gene

NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174

G

melanocortin 4 receptor

increases expression

ISO

Glyphosate results in increased expression of MC4R mRNA

NCBI chr18:62,689,798...62,691,685

G

melanoma cell adhesion molecule

increases expression

ISO

Glyphosate results in increased expression of MCAM protein

NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406

G

malonyl-CoA-acyl carrier protein transacylase

increases expression

ISO

Glyphosate results in increased expression of MCAT mRNA

NCBI chr 7:116,573,632...116,585,767
Ensembl chr 7:116,573,368...116,584,562

G

methylmalonyl CoA epimerase

increases expression

ISO

Glyphosate results in increased expression of MCEE protein

NCBI chr 1:127,376,311...127,399,551
Ensembl chr 1:127,376,298...127,400,367

G

MCL1 apoptosis regulator, BCL2 family member

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of MCL1 mRNA
Glyphosate results in increased expression of MCL1 mRNA

PMID:31295307 PMID:31874349

NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782

G

minichromosome maintenance complex component 2

decreases expression

ISO

Glyphosate results in decreased expression of MCM2 mRNA

NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094

G

minichromosome maintenance complex component 3

decreases expression

ISO

Glyphosate results in decreased expression of MCM3 mRNA

NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746

G

minichromosome maintenance complex component 4

decreases expression

ISO

Glyphosate results in decreased expression of MCM4 mRNA

NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536

G

minichromosome maintenance complex component 5

decreases expression

ISO

Glyphosate results in decreased expression of MCM5 mRNA

NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758

G

minichromosome maintenance complex component 6

decreases expression

ISO

Glyphosate results in decreased expression of MCM6 mRNA

NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467

G

minichromosome maintenance complex component 7

decreases expression

ISO

Glyphosate results in decreased expression of MCM7 mRNA

NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771

G

minichromosome maintenance 9 homologous recombination repair factor

increases methylation

EXP

Glyphosate results in increased methylation of MCM9 gene

NCBI chr20:33,369,325...33,472,243
Ensembl chr20:33,387,611...33,472,243

G

multiple C2 and transmembrane domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of MCTP1 gene

NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:7,803,382...8,493,596

G

MDM2 proto-oncogene

decreases expression

ISO

Glyphosate results in decreased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

MDS1 and EVI1 complex locus

increases expression
decreases expression

ISO

Glyphosate results in increased expression of MECOM mRNA
Glyphosate results in decreased expression of MECOM mRNA

NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038

G

mediator complex subunit 1

increases expression

ISO

Glyphosate results in increased expression of MED1 mRNA

NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545

G

mediator complex subunit 12L

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MED12L mRNA

NCBI chr 2:145,403,318...145,726,317
Ensembl chr 2:145,404,375...145,723,516

G

mediator complex subunit 13L

increases methylation

EXP

Glyphosate results in increased methylation of MED13L gene

NCBI chr12:43,468,556...43,665,819
Ensembl chr12:43,468,556...43,665,819

G

multiple EGF-like domains 10

decreases methylation

EXP

Glyphosate results in decreased methylation of MEGF10 gene

NCBI chr18:52,803,292...52,953,431
Ensembl chr18:52,847,781...52,950,675

G

Meis homeobox 2

decreases expression

EXP

Glyphosate results in decreased expression of MEIS2 mRNA

NCBI chr 3:123,197,066...123,399,002
Ensembl chr 3:123,197,066...123,397,751

G

menin 1

increases expression

EXP

Glyphosate results in increased expression of MEN1 mRNA

NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:213,068,166...213,074,120

G

mesenchyme homeobox 1

increases methylation

EXP

Glyphosate results in increased methylation of MEOX1 gene

NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976

G

methionyl aminopeptidase 2, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of METAP2-PS1 gene

NCBI chr18:51,809,682...51,811,667
Ensembl chr18:51,809,804...51,811,689

G

methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of METTL14 mRNA

NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:214,215,165...214,231,412

G

mex-3 RNA binding family member B

decreases expression

ISO

Glyphosate results in decreased expression of MEX3B mRNA

NCBI chr 1:146,264,319...146,268,554
Ensembl chr 1:146,264,318...146,268,543

G

microfibril associated protein 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MFAP4 mRNA

NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740

G

microfibril associated protein 5

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of MFAP5 gene

NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:157,395,597...157,422,448

G

membrane frizzled-related protein

decreases expression

EXP

Glyphosate results in decreased expression of MFRP mRNA

NCBI chr 8:53,342,483...53,347,696
Ensembl chr 8:53,342,534...53,347,861

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

ISO

Glyphosate results in increased expression of MFSD2A mRNA

NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916

G

MICAL-like 1

increases expression

ISO

Glyphosate results in increased expression of MICALL1 mRNA

NCBI chr 7:112,557,192...112,587,618
Ensembl chr 7:112,557,192...112,587,618

G

macrophage migration inhibitory factor

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIF mRNA

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

multiple inositol-polyphosphate phosphatase 1

increases expression

ISO

Glyphosate results in increased expression of MINPP1 mRNA

NCBI chr 1:239,766,809...239,793,023
Ensembl chr 1:239,767,286...239,793,015

G

mirror-image polydactyly 1

affects methylation

EXP

Glyphosate affects the methylation of MIPOL1 gene

NCBI chr 6:80,490,330...80,825,413
Ensembl chr 6:80,490,312...80,825,413

G

microRNA 101a

decreases expression

ISO

Glyphosate results in decreased expression of MIR101A mRNA

NCBI chr 5:121,081,683...121,081,757

G

microRNA 122

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR122 mRNA

NCBI chr18:61,028,817...61,028,901

G

microRNA 130a

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR130A mRNA

NCBI chr 3:90,229,228...90,229,315

G

microRNA 135b

decreases expression

ISO

Glyphosate results in decreased expression of MIR135B mRNA

NCBI chr13:46,191,018...46,191,114
Ensembl chr13:46,191,018...46,191,114

G

microRNA 143

increases expression

ISO

Glyphosate results in increased expression of MIR143 mRNA

NCBI chr18:57,371,349...57,371,453

G

microRNA 146a

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR146A mRNA

NCBI chr10:28,349,996...28,350,090

G

microRNA 186

increases expression

EXP

Glyphosate results in increased expression of MIR186 mRNA

NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:249,241,650...249,241,735

G

microRNA 193

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR193 mRNA

NCBI chr10:65,170,317...65,170,402

G

microRNA 19a

increases expression

ISO

Glyphosate results in increased expression of MIR19A mRNA

NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212

G

microRNA 20a

decreases expression

ISO

Glyphosate results in decreased expression of MIR20A mRNA

NCBI chr15:98,588,303...98,588,387
Ensembl chr15:98,588,303...98,588,387

G

microRNA 22

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR22 mRNA

NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425

G

microRNA 298

decreases expression

ISO

Glyphosate results in decreased expression of MIR298 mRNA

NCBI chr 3:183,470,522...183,470,603

G

microRNA 301a

increases expression

ISO

Glyphosate results in increased expression of MIR301 mRNA

NCBI chr10:72,422,599...72,422,698
Ensembl chr10:72,422,599...72,422,698

G

microRNA 32

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR32 mRNA

NCBI chr 5:76,391,285...76,391,354

G

microRNA 33

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR33 mRNA

NCBI chr 7:115,593,952...115,594,020
Ensembl chr 7:115,593,952...115,594,020

G

microRNA 340

increases expression

ISO

Glyphosate results in increased expression of MIR340 mRNA

NCBI chr10:34,894,650...34,894,747
Ensembl chr10:34,894,650...34,894,747

G

microRNA 363

decreases expression

ISO

Glyphosate results in decreased expression of MIR363 mRNA

NCBI chr X:137,342,777...137,342,863

G

microRNA 375

decreases expression

ISO

Glyphosate results in decreased expression of MIR375 mRNA

NCBI chr 9:83,906,582...83,906,656

G

microRNA 382

decreases expression

ISO

Glyphosate results in decreased expression of MIR382 mRNA

NCBI chr 6:134,569,944...134,570,023

G

microRNA 409

decreases expression

ISO

Glyphosate results in decreased expression of MIR409 mRNA

NCBI chr 6:134,579,185...134,579,261

G

microRNA 455

decreases expression

ISO

Glyphosate results in decreased expression of MIR455 mRNA

NCBI chr 5:81,704,834...81,704,911
Ensembl chr 5:81,704,834...81,704,911

G

microRNA 486

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR486 mRNA

G

microRNA 504

decreases expression

ISO

Glyphosate results in decreased expression of MIR504 mRNA

NCBI chr X:142,354,419...142,354,495

G

microRNA 532

increases expression

ISO

Glyphosate results in increased expression of MIR532 mRNA

NCBI chr X:17,919,185...17,919,263
Ensembl chr X:17,919,185...17,919,263

G

microRNA 542

increases expression

ISO

Glyphosate results in increased expression of MIR542 mRNA

NCBI chr X:137,722,176...137,722,254

G

microRNA 582

increases expression

ISO

Glyphosate results in increased expression of MIR582 mRNA

NCBI chr 2:42,661,954...42,662,034
Ensembl chr 2:42,661,954...42,662,034

G

microRNA 671

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of MIR671 mRNA
Glyphosate results in increased expression of MIR671 mRNA

NCBI chr 4:11,473,194...11,473,274

G

microRNA 99a

increases expression

ISO

Glyphosate results in increased expression of MIR99A mRNA

NCBI chr11:29,687,392...29,687,472
Ensembl chr11:29,687,392...29,687,472

G

microRNA let-7d

decreases expression

ISO

Glyphosate results in decreased expression of MIRLET7D mRNA

NCBI chr17:16,322,260...16,322,357
Ensembl chr17:16,322,260...16,322,357

G

microRNA let-7g

increases expression

ISO

Glyphosate results in increased expression of MIRLET7G mRNA

NCBI chr 8:115,701,020...115,701,107
Ensembl chr 8:115,701,007...115,701,115

G

marker of proliferation Ki-67

increases expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of MKI67 protein
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MKI67 mRNA

PMID:27486271 PMID:37567420

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

MAPK interacting serine/threonine kinase 2

increases expression

ISO

Glyphosate results in increased expression of MKNK2 mRNA

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

malectin

increases expression

ISO

Glyphosate results in increased expression of MLEC protein

NCBI chr12:47,118,918...47,133,598
Ensembl chr12:47,118,855...47,130,064

G

myeloid leukemia factor 1

decreases expression

EXP

Glyphosate results in decreased expression of MLF1 mRNA

NCBI chr 2:153,958,060...153,991,705
Ensembl chr 2:153,958,546...153,994,220

G

mutL homolog 3

decreases expression

ISO

Glyphosate results in decreased expression of MLH3 mRNA

NCBI chr 6:110,612,535...110,649,408
Ensembl chr 6:110,612,535...110,648,999

G

MLX interacting protein-like

decreases expression

ISO

Glyphosate results in decreased expression of MLXIPL protein

NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660

G

malonyl-CoA decarboxylase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MLYCD mRNA

NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446

G

matrix metallopeptidase 25

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MMP25 mRNA

NCBI chr10:13,164,974...13,180,503
Ensembl chr10:13,164,977...13,180,503

G

myeloid cell nuclear differentiation antigen

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFI204 mRNA

NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537

G

MOB kinase activator 1A

decreases expression

ISO

Glyphosate results in decreased expression of MOB1A protein

NCBI chr 4:117,389,278...117,406,255
Ensembl chr 4:117,389,186...117,406,250

G

myelin-associated oligodendrocyte basic protein

increases expression

ISO

Glyphosate results in increased expression of MOBP mRNA

NCBI chr 8:128,747,117...128,777,238
Ensembl chr 8:128,747,232...128,777,936

G

molybdenum cofactor synthesis 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MOCS2 mRNA

NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394

G

MORC family CW-type zinc finger 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MORC3 mRNA

NCBI chr11:46,621,575...46,664,315
Ensembl chr11:46,621,548...46,664,309

G

motile sperm domain containing 2

increases methylation

EXP

Glyphosate results in increased methylation of MOSPD2 gene

NCBI chr X:33,052,063...33,105,550
Ensembl chr X:33,052,004...33,107,635

G

motile sperm domain containing 4

decreases expression

EXP

Glyphosate results in decreased expression of MOSPD4 mRNA

NCBI chr18:41,377,129...41,377,946
Ensembl chr18:41,377,129...41,377,946

G

mitochondrial pyruvate carrier 1

increases expression

ISO

Glyphosate results in increased expression of MPC1 mRNA

NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064

G

myelin protein zero-like 2

decreases expression

EXP

Glyphosate results in decreased expression of MPZL2 mRNA

NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:54,243,556...54,256,074

G

major histocompatibility complex, class I-related

increases expression

EXP

Glyphosate results in increased expression of MR1 mRNA

NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502

G

MRG domain binding protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRGBP mRNA

NCBI chr 3:188,074,695...188,078,162
Ensembl chr 3:188,074,709...188,078,153

G

methylthioribose-1-phosphate isomerase 1

decreases expression

ISO

Glyphosate results in decreased expression of MRI1 protein

NCBI chr19:40,812,114...40,819,846
Ensembl chr19:40,812,094...40,822,607

G

MRN complex interacting protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRNIP mRNA

NCBI chr10:35,002,440...35,026,555

G

mitochondrial ribosomal protein L44

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPL44 mRNA

NCBI chr 9:88,555,050...88,560,101
Ensembl chr 9:88,555,019...88,561,215

G

mitochondrial ribosomal protein L46

decreases expression

EXP

Glyphosate results in decreased expression of MRPL46 mRNA

NCBI chr 1:142,108,266...142,117,030
Ensembl chr 1:142,106,531...142,117,030

G

mitochondrial ribosomal protein S18B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPS18B mRNA

NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065

G

mitochondrial ribosomal protein S35

affects methylation

EXP

Glyphosate affects the methylation of MRPS35 gene

NCBI chr 4:181,688,715...181,719,403
Ensembl chr 4:181,688,614...181,730,118

G

mitochondrial ribosomal protein S9

affects methylation

EXP

Glyphosate affects the methylation of MRPS9 gene

NCBI chr 9:52,605,678...52,664,499
Ensembl chr 9:52,605,678...52,664,499

G

membrane spanning 4-domains A1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of MS4A1 mRNA

NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447

G

membrane spanning 4-domains A6A

multiple interactions
decreases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MS4A6C mRNA
Glyphosate results in decreased expression of MS4A6A mRNA

PMID:37567420 PMID:38314887

NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013

G

mutS homolog 2

decreases expression

ISO

Glyphosate results in decreased expression of MSH2 mRNA

NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503

G

mutS homolog 4

affects methylation

ISO

Glyphosate affects the methylation of MSH4 promoter

NCBI chr 2:245,445,118...245,504,493
Ensembl chr 2:245,452,240...245,503,358

G

mutS homolog 5

increases expression

EXP

Glyphosate results in increased expression of MSH5 mRNA

NCBI chr20:3,779,180...3,797,996
Ensembl chr20:3,781,578...3,797,994

G

mesothelin

decreases expression

EXP

Glyphosate results in decreased expression of MSLN mRNA

NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153

G

macrophage scavenger receptor 1

multiple interactions
decreases methylation

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MSR1 mRNA
Glyphosate results in decreased methylation of MSR1 gene

PMID:31011160 PMID:37567420

NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070

G

methionine sulfoxide reductase B3

decreases methylation

EXP

Glyphosate results in decreased methylation of MSRB3 gene

NCBI chr 7:58,188,827...58,311,459
Ensembl chr 7:57,968,124...58,311,116

G

mitochondrially encoded cytochrome c oxidase I

decreases expression

ISO

Glyphosate results in decreased expression of COX1 mRNA; Glyphosate results in decreased expression of COX1 protein

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853

G

mitochondrially encoded cytochrome c oxidase III

decreases expression

ISO

Glyphosate results in decreased expression of COX3 mRNA

NCBI chr MT:8,599...9,382
Ensembl chr MT:8,584...9,367

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

decreases expression

ISO

Glyphosate results in decreased expression of ND2 mRNA

NCBI chr MT:3,904...4,942
Ensembl chr MT:3,892...4,929

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3

increases expression
decreases expression

EXP
ISO

Glyphosate results in increased expression of ND3 mRNA
Glyphosate results in decreased expression of ND3 mRNA

PMID:26302742 PMID:36608876

NCBI chr MT:9,451...9,798
Ensembl chr MT:9,436...9,783

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L

decreases expression

ISO

Glyphosate results in decreased expression of ND4L mRNA

NCBI chr MT:9,870...10,166
Ensembl chr MT:9,855...10,151

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

decreases expression

ISO

Glyphosate results in decreased expression of ND5 mRNA

NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553

G

metallothionein 1A

increases expression
multiple interactions

EXP

Glyphosate results in increased expression of MT1 mRNA
Quercetin inhibits the reaction [Glyphosate results in increased expression of MT1 mRNA]

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 2

multiple interactions
increases expression

EXP

Quercetin inhibits the reaction [Glyphosate results in increased expression of MT2A mRNA]

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

mitochondrial amidoxime reducing component 1

multiple interactions
increases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MTARC1 mRNA
Glyphosate results in increased expression of MTARC1 mRNA

PMID:33854195 PMID:38314887

NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252

G

mitochondrial carrier 2

increases expression

ISO

Glyphosate results in increased expression of MTCH2 protein

NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:97,285,894...97,307,327

G

microtubule crosslinking factor 1

affects methylation

EXP

Glyphosate affects the methylation of MTCL1 gene

NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:113,753,000...113,888,098

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

decreases expression

ISO

Glyphosate results in decreased expression of MTHFD1 protein

NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:100,713,681...100,781,957

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

affects methylation

EXP

Glyphosate affects the methylation of MTHFD1L gene

NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:42,849,374...43,038,309

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

decreases expression

EXP

Glyphosate results in decreased expression of MTHFD2L mRNA

NCBI chr14:17,374,139...17,455,508
Ensembl chr14:17,374,144...17,454,322

G

myotubularin related protein 10

increases expression

ISO

Glyphosate results in increased expression of MTMR10 mRNA

NCBI chr 1:127,271,139...127,322,621
Ensembl chr 1:127,270,870...127,322,621

G

myotubularin related protein 4

increases expression

ISO

Glyphosate results in increased expression of MTMR4 mRNA

NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,889,827...72,913,598

G

mechanistic target of rapamycin kinase

decreases expression

ISO

Glyphosate results in decreased expression of MTOR mRNA

PMID:31295307 PMID:34748853

NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435

G

multivesicular body subunit 12B

affects methylation

EXP

Glyphosate affects the methylation of MVB12B gene

NCBI chr 3:37,431,636...37,590,276
Ensembl chr 3:37,431,636...37,615,407

G

major vault protein

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of MVP mRNA

NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873

G

MX dynamin like GTPase 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MX1 mRNA

NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904

G

MYB proto-oncogene, transcription factor

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of MYB mRNA
Glyphosate results in increased expression of MYB mRNA

PMID:28711546 PMID:31295307

NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:17,759,309...17,792,547

G

MYC proto-oncogene, bHLH transcription factor

affects expression
multiple interactions
increases expression

ISO
EXP

Glyphosate affects the expression of MYC mRNA
Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of MYC mRNA]

PMID:31295307 PMID:33797725

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

MYCN proto-oncogene, bHLH transcription factor

decreases expression

ISO

Glyphosate results in decreased expression of MYCN mRNA

NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508

G

myosin heavy chain 6

increases expression

EXP

Glyphosate results in increased expression of MYH6 mRNA

NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333

G

myosin, heavy chain 9

decreases expression

ISO

Glyphosate results in decreased expression of MYH9 protein

NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963

G

myosin light chain 3

increases expression

EXP

Glyphosate results in increased expression of MYL3 mRNA

NCBI chr 8:119,617,077...119,623,215
Ensembl chr 8:119,616,868...119,623,216

G

myosin regulatory light chain interacting protein

decreases expression

ISO

Glyphosate results in decreased expression of MYLIP mRNA

NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,492,826...19,514,471

G

myosin X

multiple interactions
increases methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MYO10 mRNA
Glyphosate results in increased methylation of MYO10 gene

PMID:31011160 PMID:33854195

NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:77,831,532...78,036,137

G

myosin XVI

increases methylation

EXP

Glyphosate results in increased methylation of MYO16 gene

NCBI chr16:85,586,428...86,066,537
Ensembl chr16:85,586,429...85,973,879

G

myosin Ib

decreases methylation

EXP

Glyphosate results in decreased methylation of MYO1B gene

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328

G

myosin Vb

increases methylation

EXP

Glyphosate results in increased methylation of MYO5B gene

NCBI chr18:70,313,717...70,613,918
Ensembl chr18:70,311,990...70,613,918

G

myosin VC

increases methylation
decreases expression

EXP

Glyphosate results in increased methylation of MYO5C gene
Glyphosate results in decreased expression of MYO5C mRNA

PMID:31011160 PMID:38314887

NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996

G

myosin VI

affects methylation

EXP

Glyphosate affects the methylation of MYO6 gene

NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:89,967,377...90,122,215

G

myosin IXA

decreases methylation

EXP

Glyphosate results in decreased methylation of MYO9A gene

NCBI chr 8:69,044,853...69,248,094
Ensembl chr 8:69,044,885...69,245,231

G

myosin IXb

affects expression

EXP

Glyphosate affects the expression of MYO9B mRNA

NCBI chr16:17,979,374...18,064,100
Ensembl chr16:17,979,439...18,064,332

G

myelin regulatory factor

increases expression

ISO

Glyphosate results in increased expression of MYRF mRNA

NCBI chr 1:216,279,057...216,311,155
Ensembl chr 1:216,279,057...216,311,178

G

NEDD4 binding protein 2-like 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of N4BP2L2 mRNA

NCBI chr12:4,972,967...5,038,027
Ensembl chr12:4,972,990...5,033,405

G

N(alpha)-acetyltransferase 80, NatH catalytic subunit

increases methylation

EXP

Glyphosate results in increased methylation of NAA80 gene

NCBI chr 8:117,132,957...117,136,207
Ensembl chr 8:117,133,494...117,136,207

G

NEDD8 activating enzyme E1 subunit 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NAE1 mRNA

NCBI chr19:452,462...478,591
Ensembl chr19:452,432...478,831

G

nuclear assembly factor 1 ribonucleoprotein

decreases methylation

EXP

Glyphosate results in decreased methylation of NAF1 gene

NCBI chr16:27,604,228...27,634,963
Ensembl chr16:27,603,918...27,634,963

G

nanos C2HC-type zinc finger 3

increases expression

ISO

Glyphosate results in increased expression of NANOS3 mRNA

NCBI chr19:40,889,531...40,893,699
Ensembl chr19:40,882,845...40,894,263

G

N-acetyltransferase 8 (GCN5-related) family member 5

decreases expression

EXP

Glyphosate results in decreased expression of NAT8F5 mRNA

NCBI chr 4:119,817,788...119,842,503
Ensembl chr 4:119,816,735...119,863,953

G

non-SMC condensin I complex, subunit G

multiple interactions
decreases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCAPG mRNA
Glyphosate results in decreased expression of NCAPG mRNA

PMID:37567420 PMID:38314887

NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445

G

non-SMC condensin II complex, subunit H2

increases methylation

EXP

Glyphosate results in increased methylation of NCAPH2 gene

NCBI chr 7:122,302,550...122,319,570
Ensembl chr 7:122,300,252...122,319,569

G

neutrophil cytosolic factor 1

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of NCF1 mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCF1 mRNA

PMID:35897073 PMID:37567420

NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079

G

NCK-associated protein 5

affects methylation

EXP

Glyphosate affects the methylation of NCKAP5 gene

NCBI chr13:39,922,576...40,835,849
Ensembl chr13:39,922,737...40,835,521

G

nuclear receptor co-repressor 2

affects methylation
increases expression

EXP

Glyphosate affects the methylation of NCOR2 gene
Glyphosate results in increased expression of NCOR2 mRNA

PMID:26302742 PMID:35440735

NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612

G

natural cytotoxicity triggering receptor 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCR1 mRNA

NCBI chr 1:78,657,409...78,665,255
Ensembl chr 1:78,659,262...78,703,273

G

natural cytotoxicity triggering receptor 2

affects methylation

EXP

Glyphosate affects the methylation of NCR2 gene

NCBI chr 9:20,274,057...20,324,708

G

nicastrin

decreases expression

ISO

Glyphosate results in decreased expression of NCSTN mRNA

NCBI chr13:87,062,827...87,078,839
Ensembl chr13:87,062,831...87,078,839

G

nudE neurodevelopment protein 1

increases expression

ISO

Glyphosate results in increased expression of NDE1 mRNA

NCBI chr10:1,347,010...1,391,167
Ensembl chr10:1,347,018...1,383,447

G

NDRG family member 2

decreases expression

ISO

Glyphosate results in decreased expression of NDRG2 protein

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

NDRG family member 3

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of NDRG3 gene
Glyphosate results in increased methylation of NDRG3 gene

PMID:31011160 PMID:35440735

NCBI chr 3:166,007,556...166,070,981
Ensembl chr 3:165,890,091...166,049,887

G

N-deacetylase and N-sulfotransferase 4

decreases expression

EXP

Glyphosate results in decreased expression of NDST4 mRNA

NCBI chr 2:216,461,542...216,794,035
Ensembl chr 2:216,461,543...216,794,035

G

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1

decreases methylation

EXP

Glyphosate results in decreased methylation of NDUFA10L1 gene

NCBI chr 6:65,606,866...65,608,299
Ensembl chr 6:65,606,574...65,608,305

G

NADH:ubiquinone oxidoreductase subunit A3

decreases expression

ISO

Glyphosate results in decreased expression of NDUFA3 mRNA

NCBI chr 1:74,512,928...74,515,558
Ensembl chr 1:74,512,928...74,515,558

G

Ndufa4, mitochondrial complex associated

increases expression

ISO

Glyphosate results in increased expression of NDUFA4 protein

NCBI chr 4:40,968,391...40,975,559
Ensembl chr 4:40,968,391...40,975,559

G

NADH:ubiquinone oxidoreductase subunit A5

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of NDUFA5 mRNA
Glyphosate results in increased expression of NDUFA5 protein

PMID:36608876 PMID:37208198

NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235

G

NADH:ubiquinone oxidoreductase complex assembly factor 2

affects methylation

ISO

Glyphosate affects the methylation of NDUFAF2 promoter

NCBI chr 2:41,269,141...41,380,895
Ensembl chr 2:41,269,141...41,380,763

G

NADH:ubiquinone oxidoreductase subunit B11

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of NDUFB11 gene

NCBI chr X:4,126,317...4,128,575
Ensembl chr X:4,126,245...4,128,566

G

NADH:ubiquinone oxidoreductase subunit B3

increases expression

ISO

Glyphosate results in increased expression of NDUFB3 protein

NCBI chr 9:67,623,417...67,633,629
Ensembl chr 9:67,623,614...67,633,613

G

NADH:ubiquinone oxidoreductase subunit B4

decreases expression

ISO

Glyphosate results in decreased expression of NDUFB4 protein

NCBI chr11:76,569,178...76,575,879
Ensembl chr11:76,569,178...76,575,879

G

NADH:ubiquinone oxidoreductase core subunit V1

decreases expression

ISO

Glyphosate results in decreased expression of NDUFV1 protein

NCBI chr 1:210,729,856...210,735,103
Ensembl chr 1:210,729,858...210,734,949

G

nectin cell adhesion molecule 4

decreases expression

EXP

Glyphosate results in decreased expression of NECTIN4 mRNA

NCBI chr13:86,335,027...86,354,152
Ensembl chr13:86,335,831...86,353,967

G

NEDD4 like E3 ubiquitin protein ligase

increases methylation

EXP

Glyphosate results in increased methylation of NEDD4L gene

NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824

G

neuronal growth regulator 1

increases methylation

EXP

Glyphosate results in increased methylation of NEGR1 gene

NCBI chr 2:248,283,164...249,015,538
Ensembl chr 2:248,283,353...249,018,410

G

nei-like DNA glycosylase 2

increases expression

EXP

Glyphosate results in increased expression of NEIL2 mRNA

NCBI chr15:41,620,650...41,631,551
Ensembl chr15:41,621,352...41,630,834

G

nei-like DNA glycosylase 3

decreases expression

ISO

Glyphosate results in decreased expression of NEIL3 mRNA

NCBI chr16:45,091,401...45,151,419
Ensembl chr16:45,092,200...45,151,205

G

neural EGFL like 2

affects methylation

EXP

Glyphosate affects the methylation of NELL2 gene

NCBI chr 7:128,222,333...128,542,127
Ensembl chr 7:128,078,103...128,651,917

G

nestin

increases expression

ISO

Glyphosate results in increased expression of NES mRNA; Glyphosate results in increased expression of NES protein

NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228

G

nuclear factor, erythroid 2

multiple interactions

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NFE2 mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NFE2 mRNA

PMID:33854195 PMID:37567420

NCBI chr 7:136,261,234...136,273,850
Ensembl chr 7:136,261,236...136,268,585

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
increases expression

ISO
EXP

Glyphosate results in decreased expression of NFE2L2 mRNA
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of NFE2L2 mRNA]
Glyphosate results in increased expression of NFE2L2 mRNA

PMID:33797725 PMID:34748853 PMID:36625791

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NFE2 like bZIP transcription factor 3

increases expression

EXP

Glyphosate results in increased expression of NFE2L3 mRNA

NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532

G

nuclear factor I/A

increases expression

EXP

Glyphosate results in increased expression of NFIA mRNA

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395

G

nuclear factor, interleukin 3 regulated

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826

G

nuclear factor I X

increases expression

EXP

Glyphosate results in increased expression of NFIX mRNA

NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092

G

nuclear factor kappa B subunit 1

decreases expression
increases expression

ISO
EXP

Glyphosate results in decreased expression of NFKB1 mRNA
Glyphosate results in increased expression of NFKB1 mRNA

PMID:31874349 PMID:32045792 PMID:34748853

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

nuclear factor kappa B subunit 2

increases expression

ISO

Glyphosate results in increased expression of NFKB2 mRNA

NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637

G

NFKB inhibitor alpha

increases expression

ISO

Glyphosate results in increased expression of NFKBIA mRNA

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

NFKB inhibitor delta

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NFKBID mRNA

NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861

G

neuroglobin

increases expression

EXP

Glyphosate results in increased expression of NGB mRNA

NCBI chr 6:112,475,332...112,480,786
Ensembl chr 6:112,475,332...112,480,786

G

NHL repeat containing 3

decreases expression

ISO

Glyphosate results in decreased expression of NHLRC3 mRNA

NCBI chr 2:139,678,127...139,692,423
Ensembl chr 2:139,679,866...139,692,691

G

NHS actin remodeling regulator

increases expression

ISO

Glyphosate results in increased expression of NHS mRNA

NCBI chr X:36,185,067...36,524,711
Ensembl chr X:36,438,178...36,524,708

G

NFKB activating protein-like

affects methylation

EXP

Glyphosate affects the methylation of NKAPL gene

NCBI chr17:47,830,828...47,832,345
Ensembl chr17:47,829,788...47,834,443

G

natural killer cell granule protein 7

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NKG7 mRNA

NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562

G

NTPase, KAP family P-loop domain containing 1

decreases methylation

EXP

Glyphosate results in decreased methylation of NKPD1 gene

NCBI chr 1:88,293,626...88,303,117
Ensembl chr 1:88,295,091...88,302,224

G

NK2 homeobox 1

increases expression

EXP

Glyphosate results in increased expression of NKX2-1 mRNA

NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:79,731,677...79,736,441

G

NLR family, CARD domain containing 5

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NLRC5 mRNA

NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,483,755...10,555,786

G

NLR family, pyrin domain containing 14

increases methylation

EXP

Glyphosate results in increased methylation of NLRP14 gene

NCBI chr 1:170,472,956...170,500,962
Ensembl chr 1:170,472,731...170,500,949

G

NLR family, pyrin domain containing 3

increases methylation

EXP

Glyphosate results in increased methylation of NLRP3 gene

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

NLR family, pyrin domain containing 4A

affects methylation

EXP

Glyphosate affects the methylation of NLRP4A gene

NCBI chr 1:75,086,422...75,173,426
Ensembl chr 1:75,086,422...75,173,426

G

NME/NM23 nucleoside diphosphate kinase 2

decreases expression

ISO

Glyphosate results in decreased expression of NME2 mRNA

NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497

G

NME/NM23 family member 9

decreases expression

EXP

Glyphosate results in decreased expression of NME9 mRNA

NCBI chr 8:108,892,561...108,913,628

G

nicotinamide nucleotide adenylyltransferase 1

decreases methylation

EXP

Glyphosate results in decreased methylation of NMNAT1 gene

NCBI chr 5:165,193,301...165,211,213
Ensembl chr 5:165,193,302...165,211,231

G

nicotinamide nucleotide adenylyltransferase 2

increases methylation

EXP

Glyphosate results in increased methylation of NMNAT2 gene

NCBI chr13:67,655,794...67,831,609
Ensembl chr13:67,655,807...67,831,608

G

nicotinamide nucleotide transhydrogenase

increases expression

ISO

Glyphosate results in increased expression of NNT mRNA

NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310

G

nucleolar protein 3

increases expression

ISO

Glyphosate results in increased expression of NOL3 mRNA

NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722

G

nucleolar protein 7

affects methylation

ISO

Glyphosate affects the methylation of NOL7 gene

NCBI chr17:21,509,605...21,512,879
Ensembl chr17:21,509,605...21,513,196

G

nucleolar and coiled-body phosphoprotein 1

increases expression

ISO

Glyphosate results in increased expression of NOLC1 protein

NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069

G

nitric oxide synthase 2

decreases expression

EXP

Glyphosate results in decreased expression of NOS2 mRNA

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

notch receptor 1

increases expression
increases activity
increases methylation
decreases expression

ISO
EXP

Glyphosate results in increased expression of NOTCH1 mRNA
Glyphosate results in increased activity of NOTCH1 protein
Glyphosate results in increased methylation of NOTCH1 gene
Glyphosate results in decreased expression of NOTCH1 mRNA

PMID:31011160 PMID:31295307 PMID:34953950 PMID:35485992

NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613

G

notch receptor 4

increases methylation

EXP

Glyphosate results in increased methylation of NOTCH4 gene

NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072

G

NADPH oxidase 1

multiple interactions
increases expression

EXP

Fulvestrant inhibits the reaction [Glyphosate results in increased expression of NOX1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of CAT protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of CLDN1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of GJA1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of GPX1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of OCLN protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of SOD2 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of TJP1 protein]
Glyphosate results in increased expression of NOX1 mRNA; Glyphosate results in increased expression of NOX1 protein

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520

G

neuronal PAS domain protein 2

increases methylation

EXP

Glyphosate results in increased methylation of NPAS2 gene

NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037

G

neuronal PAS domain protein 4

increases expression

EXP

Glyphosate results in increased expression of NPAS4 mRNA

NCBI chr 1:211,710,640...211,728,038
Ensembl chr 1:211,711,338...211,716,102

G

neuropeptide FF receptor 1

increases expression

EXP

Glyphosate results in increased expression of NPFFR1 mRNA

NCBI chr20:30,082,604...30,116,752
Ensembl chr20:30,082,604...30,114,998

G

nuclear receptor subfamily 0, group B, member 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR0B2 mRNA

NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475

G

nuclear receptor subfamily 1, group D, member 1

increases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of NR1D1 mRNA; Glyphosate results in increased expression of NR1D1 protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D1 mRNA

PMID:33854195 PMID:33957581 PMID:34850229

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812

G

nuclear receptor subfamily 1, group D, member 2

multiple interactions
increases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D2 mRNA
Glyphosate results in increased expression of NR1D2 mRNA

PMID:33854195 PMID:34850229

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330

G

nuclear receptor subfamily 1, group H, member 4

increases expression

ISO

Glyphosate results in increased expression of NR1H4 mRNA

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

nuclear receptor subfamily 1, group I, member 3

affects methylation

EXP

Glyphosate affects the methylation of NR1I3 gene

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

nuclear receptor subfamily 2, group F, member 2

decreases expression

EXP

Glyphosate results in decreased expression of NR2F2 mRNA

NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:133,420,227...133,431,975

G

nuclear receptor subfamily 4, group A, member 3

increases expression

EXP

Glyphosate results in increased expression of NR4A3 mRNA

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285

G

NRAS proto-oncogene, GTPase

decreases expression

ISO

Glyphosate results in decreased expression of NRAS mRNA

NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543

G

neuregulin 3

affects methylation

EXP

Glyphosate affects the methylation of NRG3 gene

NCBI chr16:14,256,540...15,374,107
Ensembl chr16:14,257,148...15,374,147

G

neurogranin

decreases expression

EXP

Glyphosate results in decreased expression of NRGN mRNA

NCBI chr 8:45,444,223...45,452,417
Ensembl chr 8:45,444,223...45,452,417

G

negative regulator of reactive oxygen species

increases expression

ISO

Glyphosate results in increased expression of NRROS mRNA

NCBI chr11:82,133,608...82,151,160
Ensembl chr11:82,133,144...82,151,308

G

neurexin 1

increases methylation

EXP

Glyphosate results in increased methylation of NRXN1 gene

NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:8,935,523...10,077,374

G

neurexin 2

affects methylation

EXP

Glyphosate affects the methylation of NRXN2 gene

NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:213,155,673...213,271,526

G

NSA2 ribosome biogenesis factor, pseudogene 20

decreases expression

EXP

Glyphosate results in decreased expression of NSA2-PS20 mRNA

NCBI chr 3:82,684,517...82,685,609

G

nuclear receptor binding SET domain protein 1

increases expression

EXP

Glyphosate results in increased expression of NSD1 mRNA

NCBI chr17:9,317,085...9,431,528
Ensembl chr17:9,317,085...9,452,250

G

neuronal vesicle trafficking associated 2

affects methylation

EXP

Glyphosate affects the methylation of NSG2 gene

NCBI chr10:16,106,073...16,165,915
Ensembl chr10:16,147,325...16,165,915

G

NSE4 homolog A, SMC5-SMC6 complex component

affects methylation

ISO

Glyphosate affects the methylation of NSMCE4A gene

NCBI chr 1:194,532,364...194,539,456
Ensembl chr 1:194,525,648...194,539,456

G

neurotrophin 4

increases methylation

EXP

Glyphosate results in increased methylation of NTF4 gene

NCBI chr 1:105,030,035...105,032,866
Ensembl chr 1:105,029,764...105,034,038

G

neurotrimin

affects methylation

EXP

Glyphosate affects the methylation of NTM gene

NCBI chr 8:35,634,929...36,625,081
Ensembl chr 8:35,635,640...36,624,807

G

neurotrophic receptor tyrosine kinase 2

increases expression

ISO

Glyphosate results in increased expression of NTRK2 mRNA

NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628

G

NUBP iron-sulfur cluster assembly factor, mitochondrial

increases methylation

EXP

Glyphosate results in increased methylation of NUBPL gene

NCBI chr 6:75,294,609...75,516,603
Ensembl chr 6:75,294,632...75,516,601

G

nuclear casein kinase and cyclin-dependent kinase substrate 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NUCKS1 mRNA

NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101

G

nudix hydrolase 13

affects methylation

EXP

Glyphosate affects the methylation of NUDT13 gene

NCBI chr15:4,050,979...4,071,605
Ensembl chr15:4,050,980...4,071,476

G

NUF2 component of NDC80 kinetochore complex

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NUF2 mRNA

NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598

G

nucleoporin 214

increases expression

ISO

Glyphosate results in increased expression of NUP214 protein

NCBI chr 3:35,652,841...35,738,323
Ensembl chr 3:35,652,858...35,739,192

G

neurexophilin and PC-esterase domain family, member 1

increases methylation

EXP

Glyphosate results in increased methylation of NXPE1 gene

NCBI chr 8:57,642,308...57,670,280
Ensembl chr 8:57,651,717...57,670,282

G

neurexophilin and PC-esterase domain family member 4

decreases expression

EXP

Glyphosate results in decreased expression of NXPE4 mRNA

NCBI chr 8:57,399,199...57,640,629
Ensembl chr 8:57,631,895...57,644,186

G

2'-5'-oligoadenylate synthetase-like

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of OASL1 mRNA

NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483

G

2'-5' oligoadenylate synthetase-like 2

decreases expression

EXP

Glyphosate results in decreased expression of OASL2 mRNA

NCBI chr12:47,369,829...47,383,337
Ensembl chr12:47,370,028...47,383,185

G

ornithine decarboxylase antizyme 1

decreases methylation

EXP

Glyphosate results in decreased methylation of OAZ1 gene

NCBI chr 7:9,534,530...9,536,990
Ensembl chr 7:9,533,811...9,536,990

G

ornithine decarboxylase antizyme 2

affects expression

EXP

Glyphosate affects the expression of OAZ2 mRNA

NCBI chr 8:75,094,817...75,108,634
Ensembl chr 8:75,094,798...75,108,630

G

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

increases methylation
multiple interactions

EXP
ISO

Glyphosate results in increased methylation of OBSCN gene
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of OBSCN mRNA

PMID:31011160 PMID:37567420

NCBI chr10:44,273,686...44,419,275
Ensembl chr10:44,288,866...44,419,297

G

occludin

multiple interactions
decreases expression

EXP
ISO

Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of OCLN protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of OCLN protein]
Glyphosate results in decreased expression of OCLN mRNA; Glyphosate results in decreased expression of OCLN protein

PMID:30605748 PMID:34906888

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

outer dynein arm docking complex subunit 2

increases expression

ISO

Glyphosate results in increased expression of ODAD2 mRNA

NCBI chr17:59,910,665...60,104,929
Ensembl chr17:59,910,757...60,103,547

G

outer dynein arm docking complex subunit 4

decreases expression

EXP

Glyphosate results in decreased expression of ODAD4 mRNA

NCBI chr10:85,980,440...86,008,943
Ensembl chr10:85,980,440...86,008,943

G

8-oxoguanine DNA glycosylase

decreases expression
affects activity
increases expression

ISO

Glyphosate results in decreased expression of OGG1 mRNA
Glyphosate affects the activity of OGG1 protein
Glyphosate results in increased expression of OGG1 mRNA; Glyphosate results in increased expression of OGG1 protein

PMID:29359425 PMID:31295307

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604

G

osteoglycin

decreases expression

EXP

Glyphosate results in decreased expression of OGN mRNA

NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252

G

oligodendrocyte transcription factor 2

decreases expression

ISO

Glyphosate results in decreased expression of OLIG2 mRNA

NCBI chr11:43,961,585...43,964,961
Ensembl chr11:43,958,940...43,968,634

G

oligodendrocyte transcription factor 3

increases methylation

EXP

Glyphosate results in increased methylation of OLIG3 gene

NCBI chr 1:15,900,881...15,902,953
Ensembl chr 1:15,900,736...15,902,274

G

olfactory receptor 1675

affects methylation

EXP

Glyphosate affects the methylation of OLR1675 gene

NCBI chr20:297,130...298,068
Ensembl chr20:297,130...298,068

G

olfactory receptor pseudogene 1756

affects methylation

EXP

Glyphosate affects the methylation of OLR1756-PS gene

G

olfactory receptor 623

decreases methylation

EXP

Glyphosate results in decreased methylation of OLR623 gene

NCBI chr 3:94,306,386...94,307,321
Ensembl chr 3:94,306,386...94,307,321

G

olfactory receptor 943

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of OLR943 gene

NCBI chr 7:4,038,349...4,039,287
Ensembl chr 7:4,038,349...4,039,287

G

opioid binding protein/cell adhesion molecule-like

affects methylation

EXP

Glyphosate affects the methylation of OPCML gene

NCBI chr 8:34,451,629...35,562,897
Ensembl chr 8:34,451,500...35,558,966

G

5-oxoprolinase (ATP-hydrolysing)

decreases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of OPLAH protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of OPLAH mRNA

PMID:33854195 PMID:37208198

NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:109,891,405...109,915,979

G

opioid related nociceptin receptor 1

increases expression

ISO

Glyphosate results in increased expression of OPRL1 mRNA

NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:189,212,175...189,217,426

G

optineurin

affects methylation

EXP

Glyphosate affects the methylation of OPTN gene

NCBI chr17:78,118,847...78,169,543
Ensembl chr17:78,118,866...78,169,543

G

olfactory receptor family 10 subfamily A member 3C

increases methylation

EXP

Glyphosate results in increased methylation of OR10A3C gene

NCBI chr 1:172,304,950...172,305,894
Ensembl chr 1:172,304,950...172,305,930

G

olfactory receptor family 10 subfamily AM member 5

affects methylation

EXP

Glyphosate affects the methylation of OR10AM5 gene

NCBI chr 1:76,368,159...76,369,112
Ensembl chr 1:76,368,159...76,369,112

G

olfactory receptor family 10 subfamily AP member 1, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of OR10AP1-PS1 gene

NCBI chr X:1,448,770...1,449,231

G

olfactory receptor family 10 subfamily AP member 2, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of OR10AP2-PS1 gene

G

olfactory receptor family 10 subfamily AX member 1, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of OR10AX1-PS1 gene

NCBI chr11:7,095,402...7,096,020

G

olfactory receptor family 10 subfamily G member 3C

decreases methylation

EXP

Glyphosate results in decreased methylation of OR10G3C gene

NCBI chr15:27,551,515...27,552,456
Ensembl chr15:27,551,515...27,552,456

G

olfactory receptor family 10 subfamily J member 3

increases expression

ISO

Glyphosate results in increased expression of OR10J3 mRNA

NCBI chr13:88,199,580...88,200,521
Ensembl chr13:88,199,580...88,200,521

G

olfactory receptor family 1 subfamily J member 4

decreases expression

ISO

Glyphosate results in decreased expression of OR1J4 mRNA

NCBI chr 3:40,800,528...40,801,466
Ensembl chr 3:40,800,528...40,801,466

G

olfactory receptor family 2 subfamily B member 11

increases methylation

EXP

Glyphosate results in increased methylation of OR2B11 gene

NCBI chr10:44,857,952...44,858,908
Ensembl chr10:44,856,938...44,860,595

G

olfactory receptor family 2 subfamily N member 1J

affects methylation

EXP

Glyphosate affects the methylation of OR2N1J gene

NCBI chr20:374,125...375,063
Ensembl chr20:374,125...375,078

G

olfactory receptor family 2 subfamily N member 1K

affects methylation

EXP

Glyphosate affects the methylation of OR2N1K gene

NCBI chr20:358,953...359,996

G

olfactory receptor family 2 subfamily N member 1N

affects methylation

EXP

Glyphosate affects the methylation of OR2N1N gene

NCBI chr20:332,260...335,037
Ensembl chr20:302,333...359,996

G

olfactory receptor family 4 subfamily D member 10C

decreases expression

ISO

Glyphosate results in decreased expression of OR4D10B mRNA

NCBI chr 1:218,441,392...218,442,327
Ensembl chr 1:218,441,392...218,442,327

G

olfactory receptor family 5 subfamily K member 17

decreases methylation

EXP

Glyphosate results in decreased methylation of OR5K16 gene; Glyphosate results in decreased methylation of OR5K17 gene

NCBI chr11:55,057,993...55,058,946
Ensembl chr11:55,057,993...55,058,946

G

olfactory receptor family 6 subfamily B member 6

decreases methylation

EXP

Glyphosate results in decreased methylation of OR6B2 gene

NCBI chr 1:170,224,524...170,225,468
Ensembl chr 1:170,224,524...170,225,468

G

olfactory receptor family 8 subfamily B member 35

affects methylation

EXP

Glyphosate affects the methylation of OR8B35 gene

NCBI chr 8:45,986,853...45,987,797
Ensembl chr 8:45,986,853...45,987,797

G

olfactory receptor family 9 subfamily K member 2

increases expression

ISO

Glyphosate results in increased expression of OR9K2 mRNA

NCBI chr 7:7,519,060...7,520,019
Ensembl chr 7:7,519,060...7,520,019

G

olfactory receptor family 9 subfamily R member 3C

affects methylation

EXP

Glyphosate affects the methylation of OR9R3C gene

NCBI chr 7:7,497,480...7,498,424
Ensembl chr 7:7,497,480...7,498,424

G

ORAI calcium release-activated calcium modulator 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ORAI3 gene

NCBI chr 1:191,811,671...191,816,530
Ensembl chr 1:191,811,424...191,816,530

G

origin recognition complex, subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of ORC1 mRNA

NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:128,552,991...128,577,071

G

oxysterol binding protein-like 10

affects methylation

EXP

Glyphosate affects the methylation of OSBPL10 gene

NCBI chr 8:123,536,818...123,796,822
Ensembl chr 8:123,539,235...123,796,822

G

oxysterol binding protein-like 1A

affects methylation

EXP

Glyphosate affects the methylation of OSBPL1A gene

NCBI chr18:4,178,734...4,383,511
Ensembl chr18:4,179,631...4,369,421

G

oncostatin M receptor

decreases expression

ISO

Glyphosate results in decreased expression of OSMR mRNA

NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561

G

osteoclast stimulating factor 1, pseudogene 1

decreases expression

EXP

Glyphosate results in decreased expression of OSTF1-PS1 mRNA

NCBI chr13:82,082,427...82,083,704

G

osteoclastogenesis associated transmembrane protein 1

affects methylation

EXP

Glyphosate affects the methylation of OSTM1 gene

NCBI chr20:47,653,696...47,769,248
Ensembl chr20:47,653,670...47,769,237

G

ornithine transcarbamylase

increases expression

ISO

Glyphosate results in increased expression of OTC protein

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555

G

OTU deubiquitinase 7A

affects methylation

EXP

Glyphosate affects the methylation of OTUD7A gene

NCBI chr 1:126,476,275...126,800,037
Ensembl chr 1:126,693,712...126,799,301

G

OTU deubiquitinase 7B

increases expression

ISO

Glyphosate results in increased expression of OTUD7B mRNA

NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:186,350,798...186,409,440

G

oxytocin receptor

decreases expression

EXP

Glyphosate results in decreased expression of OXTR mRNA

NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750

G

purinergic receptor P2X 6

decreases expression

EXP

Glyphosate results in decreased expression of P2RX6 mRNA

NCBI chr11:96,944,167...96,956,424
Ensembl chr11:96,944,169...96,954,646

G

purinergic receptor P2Y1

increases expression

ISO

Glyphosate results in increased expression of P2RY1 mRNA

NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027

G

PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PABIR1 gene

NCBI chr 1:231,541,411...231,542,717
Ensembl chr 1:231,537,357...231,612,411

G

poly(A) binding protein, cytoplasmic 1

increases expression

ISO

Glyphosate results in increased expression of PABPC1 protein

PMID:36173347 PMID:37208198

NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050

G

phosphofurin acidic cluster sorting protein 2

increases expression

ISO

Glyphosate results in increased expression of PACS2 mRNA

NCBI chr 6:137,918,040...137,977,767
Ensembl chr 6:137,918,051...137,977,767

G

peptidyl arginine deiminase 2

increases methylation

EXP

Glyphosate results in increased methylation of PADI2 gene

NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662

G

p21 (RAC1) activated kinase 1

increases expression

ISO

Glyphosate results in increased expression of PAK1 mRNA

NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:161,491,847...161,637,612

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

decreases expression

ISO

Glyphosate results in decreased expression of PAPSS2 protein

NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616

G

progestin and adipoQ receptor family member 8

increases expression

ISO

Glyphosate results in increased expression of PAQR8 mRNA

NCBI chr 9:30,808,921...30,858,599
Ensembl chr 9:30,808,923...30,861,043

G

progestin and adipoQ receptor family member 9

decreases expression

ISO

Glyphosate results in decreased expression of PAQR9 mRNA

NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285

G

par-3 family cell polarity regulator

increases methylation

EXP

Glyphosate results in increased methylation of PARD3 gene

NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941

G

Parkinsonism associated deglycase

increases expression

ISO

Glyphosate results in increased expression of PARK7 protein

NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825

G

poly (ADP-ribose) polymerase 1

decreases expression
multiple interactions
increases cleavage

ISO

Glyphosate results in decreased expression of PARP1 mRNA
XAF1 protein affects the reaction [Glyphosate results in increased cleavage of PARP1 protein]

PMID:29908847 PMID:31295307

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

poly (ADP-ribose) polymerase family, member 14

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PARP14 mRNA

NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195

G

poly (ADP-ribose) polymerase 2

increases expression

ISO

Glyphosate results in increased expression of PARP2 mRNA

NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891

G

PARP1 binding protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of PARPBP gene

NCBI chr 7:24,398,897...24,468,330
Ensembl chr 7:24,398,897...24,464,744

G

paired box 3

decreases expression

ISO

Glyphosate results in decreased expression of PAX3 mRNA

NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141

G

paired box 6

multiple interactions
affects expression

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of PAX6 mRNA
Glyphosate affects the expression of PAX6 mRNA

PMID:35485992 PMID:37567420

NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763

G

paired box 8

increases expression

EXP

Glyphosate results in increased expression of PAX8 mRNA

NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:27,584,002...27,640,631

G

PDZ binding kinase

multiple interactions
increases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PBK mRNA
Glyphosate results in increased expression of PBK mRNA

PMID:37567420 PMID:38314887

NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570

G

PBX homeobox 1

decreases expression

ISO

Glyphosate results in decreased expression of PBX1 protein

NCBI chr13:82,811,664...83,121,447
Ensembl chr13:82,812,131...83,121,066

G

pterin-4 alpha-carbinolamine dehydratase 1

increases expression

ISO

Glyphosate results in increased expression of PCBD1 protein

NCBI chr20:29,573,362...29,587,181
Ensembl chr20:29,573,423...29,587,180

G

poly(rC) binding protein 4

increases expression

ISO

Glyphosate results in increased expression of PCBP4 protein

NCBI chr 8:115,971,751...115,981,987
Ensembl chr 8:115,971,326...115,981,982

G

propionyl-CoA carboxylase subunit beta

increases expression

ISO

Glyphosate results in increased expression of PCCB mRNA

NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187

G

protocadherin related 15

decreases methylation

EXP

Glyphosate results in decreased methylation of PCDH15 gene

NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958

G

protocadherin alpha subfamily C, 2

decreases expression

ISO

Glyphosate results in decreased expression of PCDHAC2 mRNA

Ensembl chr18:28,855,256...29,120,227

G

polycomb group ring finger 2

decreases expression

ISO

Glyphosate results in decreased expression of PCGF2 mRNA

NCBI chr10:83,178,926...83,191,610
Ensembl chr10:83,179,916...83,183,999

G

proliferating cell nuclear antigen

decreases expression
multiple interactions
increases expression

ISO
EXP

Glyphosate results in decreased expression of PCNA mRNA
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] promotes the reaction [[lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein]; [2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] results in decreased expression of PCNA protein; [Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein
Glyphosate results in decreased expression of PCNA protein
Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of PCNA protein]
[afimoxifene results in decreased susceptibility to Glyphosate] which results in decreased expression of PCNA protein; [U 0126 results in decreased susceptibility to Glyphosate] which results in decreased expression of PCNA protein

PMID:29890199 PMID:31295307 PMID:33797725 PMID:37615203

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

pericentrin

multiple interactions

ISO

Glyphosate results in decreased expression of and affects the localization of PCNT protein

NCBI chr20:12,189,767...12,278,179
Ensembl chr20:12,192,353...12,278,178

G

proprotein convertase subtilisin/kexin type 1

decreases expression

ISO

Glyphosate results in decreased expression of PCSK1 mRNA

NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:6,129,592...6,176,974

G

proprotein convertase subtilisin/kexin type 9

increases expression

ISO

Glyphosate results in increased expression of PCSK9 mRNA

NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507

G

programmed cell death 4

decreases expression

EXP

Glyphosate results in decreased expression of PDCD4 mRNA

NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189

G

phosphodiesterase 11A

increases expression

ISO

Glyphosate results in increased expression of PDE11A mRNA

NCBI chr 3:81,320,822...81,704,397
Ensembl chr 3:81,320,822...81,680,612

G

phosphodiesterase 2A

affects methylation

EXP

Glyphosate affects the methylation of PDE2A gene

NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466

G

phosphodiesterase 9A

affects methylation

EXP

Glyphosate affects the methylation of PDE9A gene

NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286

G

platelet derived growth factor subunit A

increases expression

ISO

Glyphosate results in increased expression of PDGFA mRNA

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322

G

pyruvate dehydrogenase E1 subunit beta

decreases expression

ISO

Glyphosate results in decreased expression of PDHB protein

NCBI chr15:19,182,789...19,188,731
Ensembl chr15:19,181,208...19,188,976

G

protein disulfide isomerase family A, member 5

decreases expression

ISO

Glyphosate results in decreased expression of PDIA5 protein

NCBI chr11:78,777,436...78,892,370
Ensembl chr11:78,777,419...78,864,329

G

pyruvate dehydrogenase kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of PDK1 mRNA

NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145

G

pyruvate dehydrogenase kinase 4

increases expression

ISO

Glyphosate results in increased expression of PDK4 mRNA

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381

G

PDZ and LIM domain 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PDLIM1 mRNA

NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379

G

pyruvate dehydrogenase phosphatase catalytic subunit 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PDP1 mRNA

NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960

G

3-phosphoinositide dependent protein kinase-1

decreases expression

ISO

Glyphosate results in decreased expression of PDPK1 mRNA

NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181

G

decaprenyl diphosphate synthase subunit 1

decreases methylation

EXP

Glyphosate results in decreased methylation of PDSS1 gene

NCBI chr17:89,964,768...90,006,819
Ensembl chr17:89,968,034...90,006,817

G

pyridoxal-dependent decarboxylase domain containing 1

increases expression

ISO

Glyphosate results in increased expression of PDXDC1 protein

NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,532,485...2,620,669

G

prodynorphin

multiple interactions
affects expression
decreases expression

EXP

[Glyphosate affects the expression of PDYN protein] which results in decreased abundance of alpha-neoendorphin; [Glyphosate affects the expression of PDYN protein] which results in decreased abundance of alpha-neoendorphin metabolite; [Glyphosate affects the expression of PDYN protein] which results in decreased abundance of rimorphin
Glyphosate results in decreased expression of PDYN protein

NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:137,354,161...137,366,503

G

PDZ domain containing 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PDZD2 gene

NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478

G

PDZ domain containing 7

increases expression

ISO

Glyphosate results in increased expression of PDZD7 mRNA

NCBI chr 1:253,837,454...253,856,919
Ensembl chr 1:253,837,459...253,855,999

G

paternally expressed 10

increases expression

ISO

Glyphosate results in increased expression of PEG10 mRNA

NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:33,817,190...33,819,166
Ensembl chr 4:33,817,190...33,819,166

G

paternally expressed 3

increases expression

ISO

Glyphosate results in increased expression of PEG3 mRNA

NCBI chr 1:76,130,965...76,157,774
Ensembl chr 1:76,130,948...76,157,743

G

pellino E3 ubiquitin protein ligase family member 3

increases expression

ISO

Glyphosate results in increased expression of PELI3 mRNA

NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:211,661,610...211,672,239

G

peptidase D

increases expression

ISO

Glyphosate results in increased expression of PEPD protein

NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190

G

period circadian regulator 1

decreases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of PER1 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PER1 mRNA

PMID:33854195 PMID:36572786

NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211

G

period circadian regulator 2

decreases expression

ISO

Glyphosate results in decreased expression of PER2 mRNA

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993

G

period circadian regulator 3

multiple interactions
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PER3 mRNA
Glyphosate results in decreased expression of PER3 mRNA

PMID:33854195 PMID:36572786

NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999

G

peroxisomal biogenesis factor 11 gamma

decreases methylation

EXP

Glyphosate results in decreased methylation of PEX11G gene

NCBI chr12:6,301,461...6,329,741
Ensembl chr12:6,277,664...6,318,919

G

peroxisomal biogenesis factor 26

affects methylation

ISO

Glyphosate affects the methylation of PEX26 gene

NCBI chr 4:156,085,967...156,099,096
Ensembl chr 4:156,086,960...156,099,093

G

peroxisomal biogenesis factor 5-like

affects methylation

EXP

Glyphosate affects the methylation of PEX5L gene

NCBI chr 2:117,623,199...117,836,772
Ensembl chr 2:117,623,199...117,836,685

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

affects methylation

EXP

Glyphosate affects the methylation of PFKFB2 gene

NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

increases expression

ISO

Glyphosate results in increased expression of PFKFB3 mRNA

PMID:35897073 PMID:36572786

NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052

G

profilin 2

increases expression

ISO

Glyphosate results in increased expression of PFN2 mRNA

NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:144,205,636...144,222,936

G

phosphoglycerate mutase 2

decreases expression

ISO

Glyphosate results in decreased expression of PGAM2 mRNA

NCBI chr14:84,895,763...84,897,874
Ensembl chr14:84,895,744...84,897,894

G

piggyBac transposable element derived 5

decreases methylation

EXP

Glyphosate results in decreased methylation of PGBD5 gene

NCBI chr19:69,234,171...69,299,315
Ensembl chr19:69,234,171...69,299,560

G

placental growth factor

decreases expression

EXP

Glyphosate results in decreased expression of PGF mRNA

NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747

G

protein geranylgeranyltransferase type I subunit beta

affects methylation

EXP

Glyphosate affects the methylation of PGGT1B gene

NCBI chr18:41,138,536...41,182,145
Ensembl chr18:41,139,965...41,182,139

G

phosphoglycerate kinase 1

decreases expression
increases expression
multiple interactions

ISO
EXP

Glyphosate results in decreased expression of PGK1 mRNA
Glyphosate results in increased expression of PGK1 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PGK1 mRNA

PMID:31295307 PMID:33854195 PMID:36572786 PMID:36608876

NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959

G

progesterone receptor

increases expression
affects expression
decreases expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of PGR mRNA
Glyphosate affects the expression of PGR mRNA
Glyphosate results in decreased expression of PGR mRNA; Glyphosate results in decreased expression of PGR protein
[Endosulfan co-treated with Glyphosate] results in increased expression of PGR protein
Glyphosate results in increased expression of PGR protein

PMID:27287056 PMID:27463640 PMID:27486271 PMID:28711546 PMID:31550491 More...

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271

G

phosphatase and actin regulator 1

affects methylation

EXP

Glyphosate affects the methylation of PHACTR1 gene

NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586

G

phosphatase and actin regulator 3

increases methylation

EXP

Glyphosate results in increased methylation of PHACTR3 gene

NCBI chr 3:185,582,134...185,801,404
Ensembl chr 3:185,582,796...185,801,822

G

phosphatase and actin regulator 4

increases expression

ISO

Glyphosate results in increased expression of PHACTR4 mRNA

NCBI chr 5:149,828,716...149,904,955
Ensembl chr 5:149,833,367...149,905,187

G

PH domain containing endocytic trafficking adaptor 2

decreases expression

EXP

Glyphosate results in decreased expression of PHETA2 mRNA

NCBI chr 7:115,735,499...115,741,988
Ensembl chr 7:115,734,649...115,742,461

G

PHD finger protein 20-like 1

decreases methylation

EXP

Glyphosate results in decreased methylation of PHF20L1 gene

NCBI chr 7:100,219,598...100,285,580
Ensembl chr 7:100,219,639...100,285,580

G

PHD finger protein 24

decreases methylation

EXP

Glyphosate results in decreased methylation of PHF24 gene

NCBI chr 5:61,939,261...61,966,879
Ensembl chr 5:61,939,900...61,966,875

G

pleckstrin homology-like domain, family B, member 2

decreases methylation

EXP

Glyphosate results in decreased methylation of PHLDB2 gene

NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734

G

protein inhibitor of activated STAT, 2

decreases expression

ISO

Glyphosate results in decreased expression of PIAS2 mRNA

NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662

G

protein inhibitor of activated STAT, 2, pseudogene 1

decreases expression

EXP

Glyphosate results in decreased expression of PIAS2-PS1 mRNA

NCBI chr 3:96,672,186...96,685,787

G

protein inhibitor of activated STAT, 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIAS3 mRNA

NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:186,921,428...186,936,714

G

progesterone immunomodulatory binding factor 1

affects methylation

EXP

Glyphosate affects the methylation of PIBF1 gene

NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548

G

piercer of microtubule wall 1

decreases expression

EXP

Glyphosate results in decreased expression of PIERCE1 mRNA

NCBI chr 3:32,195,024...32,201,111
Ensembl chr 3:32,195,024...32,199,561

G

piezo-type mechanosensitive ion channel component 2

increases expression

ISO

Glyphosate results in increased expression of PIEZO2 mRNA

NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215

G

phosphatidylinositol glycan anchor biosynthesis, class N

increases expression

ISO

Glyphosate results in increased expression of PIGN mRNA

NCBI chr13:22,173,670...22,321,344
Ensembl chr13:22,176,576...22,321,379

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

increases expression

ISO

Glyphosate results in increased expression of PIK3C3 mRNA

NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

phosphoinositide-3-kinase regulatory subunit 3

increases expression
decreases expression

ISO

Glyphosate results in increased expression of PIK3R3 mRNA
Glyphosate results in decreased expression of PIK3R3 mRNA

PMID:17984146 PMID:31295307

NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762

G

phosphoinositide-3-kinase, regulatory subunit 5

increases expression

EXP

Glyphosate results in increased expression of PIK3R5 mRNA

NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539

G

Pim-1 proto-oncogene, serine/threonine kinase

increases expression

ISO

Glyphosate results in increased expression of PIM1 mRNA

NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764

G

PICALM interacting mitotic regulator

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PIMREG mRNA

NCBI chr10:57,168,136...57,173,713
Ensembl chr10:57,167,797...57,173,063

G

phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA

NCBI chr15:26,620,399...26,624,369
Ensembl chr15:26,620,401...26,624,246

G

paired-Ig-like receptor A12

affects methylation

EXP

Glyphosate affects the methylation of PIRA12 gene

NCBI chr 1:74,219,771...74,228,458

G

paired Ig-like receptor B

affects methylation
decreases expression
multiple interactions

EXP

Glyphosate affects the methylation of PIRB gene
Glyphosate results in decreased expression of PIRB mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LILRB3 mRNA

PMID:33854195 PMID:35440735 PMID:38314887

NCBI chr 1:74,414,556...74,433,015
Ensembl chr 1:74,331,291...74,422,116

G

phosphatidylinositol transfer protein, beta

increases methylation

EXP

Glyphosate results in increased methylation of PITPNB gene

NCBI chr12:50,909,140...50,958,193
Ensembl chr12:50,909,143...50,958,140

G

phosphatidylinositol transfer protein, membrane-associated 2

affects methylation

EXP

Glyphosate affects the methylation of PITPNM2 gene

NCBI chr12:38,008,399...38,140,046
Ensembl chr12:38,066,006...38,140,046

G

polycystin 1 like 1, transient receptor potential channel interacting

increases methylation

EXP

Glyphosate results in increased methylation of PKD1L1 gene

NCBI chr14:87,766,745...87,888,647
Ensembl chr14:87,760,208...87,852,259

G

polycystin 1 like 2

increases methylation

EXP

Glyphosate results in increased methylation of PKD1L2 gene

NCBI chr19:61,958,351...62,045,324
Ensembl chr19:61,958,415...62,044,358

G

pyruvate kinase M1/2

increases expression

ISO

Glyphosate results in increased expression of PKM mRNA

NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396

G

protein kinase N2

decreases expression

ISO

Glyphosate results in decreased expression of PKN2 mRNA

NCBI chr 2:234,454,001...234,559,369
Ensembl chr 2:234,454,001...234,594,649

G

phospholipase A2, group III

increases expression

ISO

Glyphosate results in increased expression of PLA2G3 mRNA

NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542

G

phospholipase A2 group IVC

increases expression

ISO

Glyphosate results in increased expression of PLA2G4C mRNA

NCBI chr 1:83,315,017...83,411,342
Ensembl chr 1:83,382,068...83,410,037

G

phospholipase C beta 1

decreases expression

ISO

Glyphosate results in decreased expression of PLCB1 mRNA

NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646

G

phospholipase C, beta 2

increases expression

EXP

Glyphosate results in increased expression of PLCB2 mRNA

NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221

G

phospholipase C, epsilon 1

decreases methylation

EXP

Glyphosate results in decreased methylation of PLCE1 gene

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828

G

phospholipase C-like 1

increases expression

ISO

Glyphosate results in increased expression of PLCL1 mRNA

NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:64,361,520...64,733,171

G

phospholipase D1

increases expression

ISO

Glyphosate results in increased expression of PLD1 mRNA

PMID:31295307 PMID:35897073

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245

G

plectin

decreases methylation

EXP

Glyphosate results in decreased methylation of PLEC gene

NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089

G

pleckstrin

affects methylation

EXP

Glyphosate affects the methylation of PLEK gene

NCBI chr14:95,598,650...95,631,326
Ensembl chr14:95,598,654...95,655,721

G

pleckstrin homology domain containing A2

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of PLEKHA2 gene
Glyphosate results in decreased expression of PLEKHA2 mRNA

PMID:35440735 PMID:38314887

NCBI chr16:73,641,338...73,704,068
Ensembl chr16:73,641,344...73,703,087

G

pleckstrin homology and FYVE domain containing 1

increases expression

ISO

Glyphosate results in increased expression of PLEKHF1 mRNA

NCBI chr 1:100,045,340...100,046,817
Ensembl chr 1:100,027,056...100,053,452

G

pleckstrin homology and RhoGEF domain containing G5

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLEKHG5 mRNA

NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229

G

pleckstrin homology, MyTH4 and FERM domain containing H1

increases expression

ISO

Glyphosate results in increased expression of PLEKHH1 mRNA

NCBI chr 6:103,572,304...103,621,729
Ensembl chr 6:103,572,291...103,621,728

G

perilipin 4

increases expression

ISO

Glyphosate results in increased expression of PLIN4 mRNA

NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:1,016,302...1,025,368

G

polo-like kinase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLK2 mRNA

NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296

G

proteolipid protein 1

increases expression

ISO

Glyphosate results in increased expression of PLP1 mRNA

NCBI chr X:104,933,921...104,993,317
Ensembl chr X:104,975,780...104,993,314

G

phospholipid phosphatase 2

increases expression

ISO

Glyphosate results in increased expression of PLPP2 mRNA

NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627

G

phospholipid phosphatase 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PLPP4 gene

NCBI chr 1:193,260,181...193,389,659
Ensembl chr 1:193,260,434...193,389,675

G

plexin B3

increases expression

ISO

Glyphosate results in increased expression of PLXNB3 mRNA

NCBI chr X:156,645,505...156,660,011
Ensembl chr X:156,645,182...156,660,003

G

phorbol-12-myristate-13-acetate-induced protein 1

multiple interactions
increases expression

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of PMAIP1 mRNA
Glyphosate results in increased expression of PMAIP1 mRNA

PMID:31295307 PMID:32800223

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382

G

phosphomevalonate kinase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PMVK mRNA

NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080

G

PNN interacting serine and arginine rich protein

increases expression

EXP

Glyphosate results in increased expression of PNISR mRNA

NCBI chr 5:40,190,214...40,219,619
Ensembl chr 5:40,192,735...40,219,611

G

PNKD metallo-beta-lactamase domain containing

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNKD mRNA

NCBI chr 9:83,317,757...83,386,263
Ensembl chr 9:83,317,738...83,386,262

G

pinin, desmosome associated protein

increases expression

EXP

Glyphosate results in increased expression of PNN mRNA

NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933

G

purine nucleoside phosphorylase

decreases expression

ISO

Glyphosate results in decreased expression of PNP2 mRNA

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162

G

proline-rich nuclear receptor coactivator 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNRC1 mRNA

NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491

G

POC1 centriolar protein A

decreases methylation

EXP

Glyphosate results in decreased methylation of POC1A gene

NCBI chr 8:115,801,335...115,869,812
Ensembl chr 8:115,801,396...115,870,392

G

DNA polymerase delta 3, accessory subunit

decreases expression

ISO

Glyphosate results in decreased expression of POLD3 mRNA

NCBI chr 1:163,830,217...163,870,015
Ensembl chr 1:163,830,437...163,869,202

G

DNA polymerase epsilon, catalytic subunit

decreases expression

ISO

Glyphosate results in decreased expression of POLE mRNA

NCBI chr12:52,005,155...52,053,761
Ensembl chr12:52,005,155...52,053,662

G

DNA polymerase epsilon 2, accessory subunit

decreases expression

ISO

Glyphosate results in decreased expression of POLE2 mRNA

NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361

G

DNA polymerase lambda

increases expression

ISO

Glyphosate results in increased expression of POLL mRNA

NCBI chr 1:254,349,229...254,357,689
Ensembl chr 1:254,349,231...254,358,020

G

DNA polymerase theta

affects methylation

EXP

Glyphosate affects the methylation of POLQ gene

NCBI chr11:77,179,190...77,281,270
Ensembl chr11:77,179,209...77,281,268

G

RNA polymerase II subunit M, pseudogene 4

affects methylation

EXP

Glyphosate affects the methylation of POLR2M-PS4 gene

NCBI chr11:98,962,805...98,963,932

G

RNA polymerase III subunit E

increases expression

ISO

Glyphosate results in increased expression of POLR3E mRNA

NCBI chr 1:184,897,383...184,925,547
Ensembl chr 1:184,897,426...184,926,534

G

POP1 homolog, ribonuclease P/MRP subunit

increases methylation

EXP

Glyphosate results in increased methylation of POP1 gene

NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:67,590,522...67,618,293

G

popeye domain cAMP effector 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of POPDC3 mRNA

NCBI chr20:50,354,775...50,383,050
Ensembl chr20:50,354,767...50,385,674

G

cytochrome p450 oxidoreductase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of POR gene

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809

G

periostin

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of POSTN protein
Glyphosate results in decreased expression of POSTN mRNA

PMID:37208198 PMID:38314887

NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300

G

protection of telomeres 1

affects methylation

EXP

Glyphosate affects the methylation of POT1 gene

NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543

G

POTE ankyrin domain family member H

decreases expression

EXP

Glyphosate results in decreased expression of POTEH mRNA

NCBI chr15:19,559,450...19,654,345

G

inorganic pyrophosphatase 1

increases expression

ISO

Glyphosate results in increased expression of PPA1 protein

PMID:36173347 PMID:37208198

NCBI chr20:30,132,088...30,160,492
Ensembl chr20:30,133,504...30,160,489

G

inorganic pyrophosphatase 2

increases expression

ISO

Glyphosate results in increased expression of PPA2 protein

NCBI chr 2:224,472,738...224,552,101
Ensembl chr 2:224,474,823...224,552,628

G

peroxisome proliferator activated receptor alpha

increases expression

ISO

Glyphosate results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

peroxisome proliferator-activated receptor delta

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PPARD mRNA

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707

G

peptidylprolyl isomerase A

decreases expression

ISO

Glyphosate results in decreased expression of PPIA protein

NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115

G

protein phosphatase, Mg2+/Mn2+ dependent, 1A

increases expression

ISO

Glyphosate results in increased expression of PPM1A mRNA

NCBI chr 6:97,174,955...97,216,585
Ensembl chr 6:97,174,916...97,216,574

G

protein phosphatase 1, regulatory subunit 21

increases methylation

EXP

Glyphosate results in increased methylation of PPP1R21 gene

NCBI chr 6:11,655,059...11,724,219
Ensembl chr 6:11,655,059...11,724,219

G

protein phosphatase 1, regulatory subunit 37

decreases methylation

EXP

Glyphosate results in decreased methylation of PPP1R37 gene

NCBI chr 1:88,308,782...88,340,796
Ensembl chr 1:88,308,782...88,340,592

G

protein phosphatase 1, regulatory subunit 7

affects methylation

EXP

Glyphosate affects the methylation of PPP1R7 gene

NCBI chr 9:101,333,472...101,358,589
Ensembl chr 9:101,333,497...101,360,959

G

protein phosphatase 2 scaffold subunit A alpha

decreases expression

ISO

Glyphosate results in decreased expression of PPP2R1A mRNA

NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242

G

protein phosphatase 2 scaffold subunit A beta

decreases expression

ISO

Glyphosate results in decreased expression of PPP2R1B mRNA

NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:60,081,553...60,125,795

G

protein phosphatase 2, regulatory subunit B'', gamma

decreases expression

EXP

Glyphosate results in decreased expression of PPP2R3C mRNA

NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:78,382,855...78,406,201

G

protein phosphatase 2, regulatory subunit B', gamma

decreases methylation

EXP

Glyphosate results in decreased methylation of PPP2R5C gene

NCBI chr 6:135,282,947...135,419,591
Ensembl chr 6:135,324,067...135,419,597

G

protein phosphatase 3 catalytic subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of PPP3CA mRNA

NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554

G

protein phosphatase 3 catalytic subunit beta

increases expression

ISO

Glyphosate results in increased expression of PPP3CB mRNA

NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203

G

protein phosphatase 3 catalytic subunit gamma

decreases expression

ISO

Glyphosate results in decreased expression of PPP3CC mRNA

NCBI chr15:51,699,586...51,771,763
Ensembl chr15:51,700,255...51,771,538

G

protein phosphatase 5, catalytic subunit

decreases expression

ISO

Glyphosate results in decreased expression of PPP5C mRNA

NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950

G

palmitoyl-protein thioesterase 1

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of PPT1 mRNA
Glyphosate results in increased expression of PPT1 mRNA

PMID:26302742 PMID:36608876

NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:140,406,214...140,427,200

G

PR/SET domain 15

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRDM15 mRNA

NCBI chr11:50,633,973...50,691,624
Ensembl chr11:50,633,973...50,691,823

G

PR/SET domain 2

increases methylation

EXP

Glyphosate results in increased methylation of PRDM2 gene

NCBI chr 5:160,704,396...160,815,184
Ensembl chr 5:160,705,462...160,815,140

G

peroxiredoxin 2

increases expression

ISO

Glyphosate results in increased expression of PRDX2 protein

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006

G

PRELI domain containing 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELID2 mRNA

NCBI chr18:34,120,989...34,212,699
Ensembl chr18:34,125,373...34,212,167

G

proline and arginine rich end leucine rich repeat protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELP mRNA

NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324

G

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

affects methylation

EXP

Glyphosate affects the methylation of PREX1 gene

NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764

G

protein kinase AMP-activated catalytic subunit alpha 2

decreases expression

ISO

Glyphosate results in decreased expression of PRKAA2 mRNA

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324

G

protein kinase cAMP-activated catalytic subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of PRKACA mRNA

NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494

G

protein kinase cAMP-activated catalytic subunit beta

affects methylation

EXP

Glyphosate affects the methylation of PRKACB gene

NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315

G

protein kinase cAMP-dependent type I regulatory subunit alpha

decreases expression

ISO

Glyphosate results in decreased expression of PRKAR1A protein

NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025

G

protein kinase cAMP-dependent type II regulatory subunit beta

decreases expression

ISO

Glyphosate results in decreased expression of PRKAR2B protein

NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411

G

protein kinase C, alpha

decreases methylation

EXP

Glyphosate results in decreased methylation of PRKCA gene

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572

G

protein kinase, DNA-activated, catalytic subunit

decreases expression

ISO

Glyphosate results in decreased expression of PRKDC mRNA

NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108

G

protein kinase cGMP-dependent 2

affects methylation

EXP

Glyphosate affects the methylation of PRKG2 gene

NCBI chr14:10,864,020...10,972,617
Ensembl chr14:10,864,186...10,972,614

G

prolactin

increases expression
affects methylation

EXP

Glyphosate results in increased expression of PRL protein
Glyphosate affects the methylation of PRL gene

PMID:30447247 PMID:35440735

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217

G

prolactin releasing hormone receptor

decreases expression

EXP

Glyphosate results in decreased expression of PRLHR mRNA

NCBI chr 1:269,592,735...269,594,422
Ensembl chr 1:269,585,611...269,594,909

G

prolactin receptor

decreases expression

ISO

Glyphosate results in decreased expression of PRLR mRNA

NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882

G

protamine 1

decreases expression

EXP

Glyphosate results in decreased expression of PRM1

NCBI chr10:5,378,740...5,379,235

G

prion protein

decreases methylation

EXP

Glyphosate results in decreased methylation of PRNP gene

NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436

G

protein C, inactivator of coagulation factors Va and VIIIa

affects methylation

EXP

Glyphosate affects the methylation of PROC gene

NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964

G

proline and serine rich 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PROSER2 mRNA

NCBI chr17:77,061,371...77,096,788
Ensembl chr17:77,077,727...77,095,194

G

prospero homeobox 1

increases methylation

EXP

Glyphosate results in increased methylation of PROX1 gene

NCBI chr13:104,196,615...104,251,007
Ensembl chr13:104,200,378...104,250,975

G

pre-mRNA processing factor 39

multiple interactions
increases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA
Glyphosate results in increased expression of PRPF39 mRNA

PMID:26302742 PMID:33854195

NCBI chr 6:88,825,227...88,851,342
Ensembl chr 6:88,825,243...88,851,341

G

pre-mRNA processing factor 4B

increases expression

EXP

Glyphosate results in increased expression of PRPF4B mRNA

NCBI chr17:30,190,721...30,230,153
Ensembl chr17:30,193,907...30,225,420

G

pre-mRNA processing factor 8

decreases expression

EXP

Glyphosate results in decreased expression of PRPF8 mRNA

NCBI chr10:60,829,778...60,852,887
Ensembl chr10:60,829,778...60,852,887

G

peripherin

decreases expression

EXP

Glyphosate results in decreased expression of PRPH mRNA

NCBI chr 7:132,096,888...132,101,070
Ensembl chr 7:132,097,285...132,101,068

G

proline-rich coiled-coil 1

affects methylation

EXP

Glyphosate affects the methylation of PRRC1 gene

NCBI chr18:53,010,606...53,047,601
Ensembl chr18:53,010,600...53,045,015

G

serine protease 1

decreases expression

ISO

Glyphosate results in decreased expression of PRSS1 protein

PMID:36173347 PMID:37208198

NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452

G

protease, serine, 3B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PRSS3B gene

NCBI chr 4:70,838,484...70,842,192
Ensembl chr 4:70,838,471...70,845,283

G

serine protease 45

increases methylation

EXP

Glyphosate results in increased methylation of PRSS45 gene

NCBI chr 8:119,698,713...119,704,492
Ensembl chr 8:119,698,713...119,704,492

G

protease, serine, 46

increases methylation

EXP

Glyphosate results in increased methylation of PRSS46 gene

NCBI chr 8:119,707,687...119,719,461
Ensembl chr 8:119,707,687...119,719,461

G

serine protease 50

increases methylation

EXP

Glyphosate results in increased methylation of PRSS50 gene

NCBI chr 8:119,719,574...119,727,269
Ensembl chr 8:119,720,776...119,727,268

G

phosphoserine aminotransferase 1

increases expression

ISO

Glyphosate results in increased expression of PSAT1 protein

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693

G

prostate stem cell antigen

decreases expression

EXP

Glyphosate results in decreased expression of PSCA mRNA

NCBI chr 7:108,483,974...108,492,098
Ensembl chr 7:108,484,184...108,492,097

G

pleckstrin and Sec7 domain containing 3

affects methylation

EXP

Glyphosate affects the methylation of PSD3 gene

NCBI chr16:26,238,595...26,802,535
Ensembl chr16:26,340,028...26,802,535

G

presenilin 2

increases expression
decreases expression

ISO

Glyphosate results in increased expression of PSEN2 mRNA
Glyphosate results in decreased expression of PSEN2 mRNA

NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116

G

proteasome 20S subunit beta 10

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PSMB10 mRNA

NCBI chr19:50,740,808...50,743,292
Ensembl chr19:50,740,811...50,743,210

G

proteasome 20S subunit beta 5

increases expression

ISO

Glyphosate results in increased expression of PSMB5 protein

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 20S subunit beta 8

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PSMB8 mRNA

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031

G

proteasome 26S subunit, ATPase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC2 mRNA

NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390

G

proteasome 26S subunit, ATPase 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA

NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060

G

proteasome 26S subunit, ATPase 5

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC5 mRNA

NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921

G

proteasome 26S subunit, non-ATPase 11

decreases expression

ISO

Glyphosate results in decreased expression of PSMD11 protein

NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 2

decreases expression

ISO

Glyphosate results in decreased expression of PSMD2 protein

NCBI chr11:93,752,761...93,763,388
Ensembl chr11:93,752,763...93,763,388

G

proteasome 26S subunit, non-ATPase 5

decreases expression

ISO

Glyphosate results in decreased expression of PSMD5 protein

NCBI chr 3:38,531,206...38,552,085
Ensembl chr 3:38,530,951...38,548,490

G

proteasome activator subunit 1

decreases expression

ISO

Glyphosate results in decreased expression of PSME1 protein

NCBI chr15:33,038,962...33,041,849
Ensembl chr15:33,038,597...33,041,848

G

proteasome activator subunit 3 interacting protein 1

increases expression

EXP

Glyphosate results in increased expression of PSME3IP1 mRNA

NCBI chr19:10,407,382...10,436,029
Ensembl chr19:10,407,552...10,436,027

G

platelet-activating factor receptor

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PTAFR mRNA

NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408

G

patched domain containing 4

affects methylation

EXP

Glyphosate affects the methylation of PTCHD4 gene

NCBI chr 9:25,951,395...26,163,296
Ensembl chr 9:25,959,954...26,163,284

G

prostaglandin D2 receptor 2

decreases expression

EXP

Glyphosate results in decreased expression of PTGDR2 mRNA

NCBI chr 1:217,010,183...217,015,044
Ensembl chr 1:216,995,629...217,022,393

G

prostaglandin E receptor 4

decreases expression

EXP

Glyphosate results in decreased expression of PTGER4 mRNA

NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135

G

prostaglandin-endoperoxide synthase 1

increases expression

EXP

Glyphosate results in increased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

prostaglandin-endoperoxide synthase 2

decreases expression
increases expression

EXP
ISO

Glyphosate results in decreased expression of PTGS2 mRNA
Glyphosate results in increased expression of PTGS2 mRNA

PMID:34953950 PMID:35489704

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

protein tyrosine kinase 2 beta

increases methylation

EXP

Glyphosate results in increased methylation of PTK2B gene

NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806

G

protein tyrosine kinase 7

affects methylation

EXP

Glyphosate affects the methylation of PTK7 gene

NCBI chr 9:21,849,756...21,916,077
Ensembl chr 9:21,849,801...21,916,078

G

pleiotrophin

decreases expression

ISO

Glyphosate results in decreased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

protein phosphatase 2 phosphatase activator

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PTPA mRNA

NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:34,087,575...34,162,772

G

protein tyrosine phosphatase domain containing 1

increases expression

ISO

Glyphosate results in increased expression of PTPDC1 mRNA

NCBI chr17:16,235,311...16,284,160
Ensembl chr17:16,235,263...16,284,158

G

protein tyrosine phosphatase, non-receptor type 11

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of PTPN11 gene
Glyphosate results in decreased expression of PTPN11 mRNA

PMID:31295307 PMID:35440735

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577

G

protein tyrosine phosphatase, non-receptor type 3

affects methylation

EXP

Glyphosate affects the methylation of PTPN3 gene

NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:76,703,687...76,860,470

G

protein tyrosine phosphatase, non-receptor type 7

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PTPN7 mRNA

NCBI chr13:49,122,679...49,136,096
Ensembl chr13:49,122,609...49,136,094

G

protein tyrosine phosphatase, receptor type, D like

decreases expression

EXP

Glyphosate results in decreased expression of PTPRDL mRNA

NCBI chr 5:97,414,616...97,426,593

G

protein tyrosine phosphatase, receptor type, F

affects methylation

EXP

Glyphosate affects the methylation of PTPRF gene

NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426

G

protein tyrosine phosphatase, receptor type, S

increases expression

ISO

Glyphosate results in increased expression of PTPRS mRNA

NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,332,559...1,394,093

G

peptidyl-tRNA hydrolase 2, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of PTRH2-PS1 gene

NCBI chr16:54,604,649...54,605,270

G

pseudouridine synthase 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PUS10 mRNA

NCBI chr14:101,822,525...101,885,187
Ensembl chr14:101,822,458...101,885,190

G

PWWP domain containing 3B

decreases expression

EXP

Glyphosate results in decreased expression of PWWP3B mRNA

NCBI chr X:107,593,062...107,627,215
Ensembl chr X:107,582,676...107,627,803

G

glycogen phosphorylase L

increases expression
decreases expression

ISO

Glyphosate results in increased expression of PYGL protein
Glyphosate results in decreased expression of PYGL protein

PMID:36173347 PMID:37208198

NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269

G

pygopus family PHD finger 2

affects expression

ISO

Glyphosate affects the expression of PYGO2 mRNA

NCBI chr 2:177,147,407...177,152,476
Ensembl chr 2:177,147,737...177,152,473

G

glutaminyl-tRNA synthetase 1

affects methylation

ISO

Glyphosate affects the methylation of QARS1 gene

NCBI chr 8:118,086,243...118,094,274
Ensembl chr 8:118,086,228...118,094,274

G

R3H domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of R3HDM1 gene

NCBI chr13:42,148,281...42,286,311
Ensembl chr13:42,148,290...42,286,311

G

RAB25, member RAS oncogene family

increases expression

ISO

Glyphosate results in increased expression of RAB25 mRNA

NCBI chr 2:176,298,124...176,304,221
Ensembl chr 2:176,298,124...176,304,221

G

RAB2A, member RAS oncogene family

affects methylation

EXP

Glyphosate affects the methylation of RAB2A gene

NCBI chr 5:26,473,424...26,537,441
Ensembl chr 5:26,473,548...26,538,488

G

RAB30, member RAS oncogene family

affects methylation

EXP

Glyphosate affects the methylation of RAB30 gene

NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778

G

RAB31, member RAS oncogene family

affects methylation

EXP

Glyphosate affects the methylation of RAB31 gene

NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092

G

RAB43, member RAS oncogene family

increases methylation

EXP

Glyphosate results in increased methylation of RAB43 gene

NCBI chr 4:121,806,992...121,826,694
Ensembl chr 4:121,806,992...121,854,561

G

RAB5B, member RAS oncogene family

increases expression

ISO

Glyphosate results in increased expression of RAB5B mRNA

NCBI chr 7:1,693,971...1,712,936
Ensembl chr 7:1,693,989...1,712,780

G

RAB5C, member RAS oncogene family

decreases expression

ISO

Glyphosate results in decreased expression of RAB5C mRNA

NCBI chr10:86,142,872...86,166,449
Ensembl chr10:86,142,873...86,166,449

G

rabaptin, RAB GTPase binding effector protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA

NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177

G

Rab9 effector protein with kelch motifs

increases methylation

EXP

Glyphosate results in increased methylation of RABEPK gene

NCBI chr 3:38,460,205...38,481,077
Ensembl chr 3:38,460,206...38,480,688

G

RAB, member of RAS oncogene family like 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABL2 mRNA

NCBI chr 7:122,531,787...122,540,500
Ensembl chr 7:122,531,792...122,540,395

G

receptor for activated C kinase 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of RACK1 mRNA
Glyphosate results in increased expression of RACK1 protein

PMID:17984146 PMID:36173347

NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948

G

RAD21 cohesin complex component like 1

decreases expression

EXP

Glyphosate results in decreased expression of RAD21L1 mRNA

NCBI chr 3:160,620,500...160,648,716
Ensembl chr 3:160,620,564...160,648,909

G

RAD51 paralog B

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of RAD51B mRNA

NCBI chr 6:103,829,390...104,373,923
Ensembl chr 6:103,829,554...104,374,509

G

retinoic acid early transcript 1E

increases expression

ISO

Glyphosate results in increased expression of RAET1E mRNA

NCBI chr 1:3,474,487...3,476,431

G

RAS like proto-oncogene A

increases expression

ISO

Glyphosate results in increased expression of RALA mRNA

NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733

G

RAS like proto-oncogene B

increases expression

ISO

Glyphosate results in increased expression of RALB mRNA

NCBI chr13:33,140,834...33,176,997
Ensembl chr13:33,140,835...33,176,998

G

Ral GTPase activating protein catalytic subunit alpha 1

increases expression

ISO

Glyphosate results in increased expression of RALGAPA1 protein

NCBI chr 6:78,712,554...78,987,486
Ensembl chr 6:78,701,832...78,987,486

G

RNA guanine-7 methyltransferase activating subunit

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RAMAC gene

NCBI chr 1:145,117,752...145,123,640
Ensembl chr 1:145,117,736...145,124,256

G

receptor activity modifying protein 1

increases methylation

EXP

Glyphosate results in increased methylation of RAMP1 gene

NCBI chr 9:99,213,031...99,263,696

G

RAN binding protein 17

increases methylation

EXP

Glyphosate results in increased methylation of RANBP17 gene

NCBI chr10:18,304,634...18,607,162
Ensembl chr10:18,305,227...18,607,047

G

RAN GTPase activating protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RANGAP1 mRNA

NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564

G

RAP1A, member of RAS oncogene family

increases methylation

EXP

Glyphosate results in increased methylation of RAP1A gene

NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808

G

Rap1 GTPase-activating protein

affects methylation

EXP

Glyphosate affects the methylation of RAP1GAP gene

NCBI chr 5:155,157,511...155,222,622
Ensembl chr 5:155,157,558...155,222,622

G

Rap guanine nucleotide exchange factor 3

increases expression

ISO

Glyphosate results in increased expression of RAPGEF3 mRNA

NCBI chr 7:130,754,883...130,777,303
Ensembl chr 7:130,754,871...130,777,668

G

Rap guanine nucleotide exchange factor 5

affects methylation
decreases methylation

EXP

Glyphosate affects the methylation of RAPGEF5 gene
Glyphosate results in decreased methylation of RAPGEF5 gene

PMID:31011160 PMID:35440735

NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

affects methylation

EXP

Glyphosate affects the methylation of RAPH1 gene

NCBI chr 9:69,397,272...69,484,174
Ensembl chr 9:69,401,517...69,484,019

G

retinoic acid receptor, beta

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of RARB gene
Glyphosate results in increased expression of RARB mRNA

PMID:33713393 PMID:35440735

NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040

G

arginyl-tRNA synthetase 1

affects methylation
multiple interactions

EXP

Glyphosate affects the methylation of RARS1 gene
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RARS1 mRNA

PMID:33854195 PMID:35440735

NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,774,805...20,799,251

G

RAS p21 protein activator 3

increases expression

ISO

Glyphosate results in increased expression of RASA3 mRNA

NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984

G

RAS p21 protein activator 4

increases expression

ISO

Glyphosate results in increased expression of RASA4B mRNA

NCBI chr12:26,189,416...26,216,801
Ensembl chr12:26,189,339...26,216,860

G

RAS protein activator like 2

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of RASAL2 mRNA
Glyphosate results in increased expression of RASAL2 mRNA

NCBI chr13:71,808,740...72,102,723
Ensembl chr13:71,813,261...72,102,723

G

RasGEF domain family, member 1C

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of RASGEF1C gene
Glyphosate results in increased methylation of RASGEF1C gene

PMID:31011160 PMID:35440735

NCBI chr10:34,728,573...34,794,763
Ensembl chr10:34,728,573...34,794,763

G

RAS guanyl releasing protein 1

decreases expression

ISO

Glyphosate results in decreased expression of RASGRP1 mRNA

NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434

G

RAS guanyl releasing protein 4

increases expression

EXP

Glyphosate results in increased expression of RASGRP4 mRNA

NCBI chr 1:93,560,513...93,580,321
Ensembl chr 1:93,560,513...93,580,323

G

Ras association domain family member 4

increases expression

ISO

Glyphosate results in increased expression of RASSF4 mRNA

NCBI chr 4:151,569,984...151,605,203
Ensembl chr 4:151,569,984...151,604,883

G

Ras association domain family member 5

increases methylation

EXP

Glyphosate results in increased methylation of RASSF5 gene

NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277

G

RB binding protein 7, chromatin remodeling factor, pseudogene 1

decreases expression

EXP

Glyphosate results in decreased expression of RBBP7-PS1 mRNA

NCBI chr16:18,117,024...18,118,403

G

RNA binding fox-1 homolog 1

affects methylation

EXP

Glyphosate affects the methylation of RBFOX1 gene

NCBI chr10:8,658,809...10,754,648
Ensembl chr10:8,658,809...10,754,706

G

RB transcriptional corepressor like 1

decreases expression

ISO

Glyphosate results in decreased expression of RBL1 mRNA

NCBI chr 3:166,226,187...166,289,862
Ensembl chr 3:166,226,198...166,289,376

G

RNA binding motif protein 14

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RBM14 mRNA

NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:211,523,972...211,535,065

G

RNA binding motif protein 19

increases methylation

EXP

Glyphosate results in increased methylation of RBM19 gene

NCBI chr12:42,026,277...42,111,530
Ensembl chr12:42,026,278...42,111,530

G

RNA binding motif protein 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RBM3 mRNA

NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841

G

RNA binding motif protein 47

decreases expression

EXP

Glyphosate results in decreased expression of RBM47 mRNA

NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,466,335...42,543,163

G

RNA binding motif, single stranded interacting protein 3

affects methylation

EXP

Glyphosate affects the methylation of RBMS3 gene

NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:125,183,315...126,503,586

G

retinol binding protein 1

increases expression

ISO

Glyphosate results in increased expression of RBP1 protein

NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847

G

recombination signal binding protein for immunoglobulin kappa J region

decreases expression

ISO

Glyphosate results in decreased expression of RBPJ mRNA

NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307

G

RNA binding protein, mRNA processing factor

affects methylation
multiple interactions

EXP

Glyphosate affects the methylation of RBPMS gene
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RBPMS gene

PMID:33854195 PMID:35440735

NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503

G

retinol dehydrogenase 7

affects methylation

EXP

Glyphosate affects the methylation of RDH7 gene

NCBI chr 7:65,561,259...65,574,618
Ensembl chr 7:65,560,822...65,574,635

G

radixin

decreases expression

ISO

Glyphosate results in decreased expression of RDX protein

NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967

G

receptor accessory protein 3

affects methylation

EXP

Glyphosate affects the methylation of REEP3 gene

NCBI chr20:21,492,695...21,575,138
Ensembl chr20:21,492,721...21,577,521

G

RELA proto-oncogene, NF-kB subunit

decreases expression
decreases phosphorylation

ISO
EXP

Glyphosate results in decreased expression of RELA mRNA
Glyphosate results in decreased phosphorylation of RELA protein

PMID:28627408 PMID:31295307

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

reelin

decreases methylation
increases expression

EXP

Glyphosate results in decreased methylation of RELN gene
Glyphosate results in increased expression of RELN mRNA

PMID:31011160 PMID:38314887

NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162

G

renin

decreases expression

ISO

Glyphosate results in decreased expression of REN1 mRNA

NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543

G

retroelement silencing factor 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RESF1 mRNA

NCBI chr 4:184,057,165...184,093,374
Ensembl chr 4:184,057,010...184,098,429

G

ret proto-oncogene

increases expression

ISO

Glyphosate results in increased expression of RET mRNA

NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556

G

REV1, DNA directed polymerase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of REV1 mRNA

NCBI chr 9:47,773,907...47,847,554
Ensembl chr 9:47,773,907...47,847,332

G

replication factor C subunit 2

decreases expression

ISO

Glyphosate results in decreased expression of RFC2 mRNA

NCBI chr12:27,756,920...27,770,049
Ensembl chr12:27,756,922...27,770,025

G

replication factor C subunit 3

decreases expression

ISO

Glyphosate results in decreased expression of RFC3 mRNA

NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340

G

replication factor C subunit 4

decreases expression

ISO

Glyphosate results in decreased expression of RFC4 mRNA

NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730

G

replication factor C subunit 5

decreases expression

ISO

Glyphosate results in decreased expression of RFC5 mRNA

NCBI chr12:44,868,322...44,877,879
Ensembl chr12:44,862,329...44,878,151

G

raftlin lipid raft linker 1

increases expression

ISO

Glyphosate results in increased expression of RFTN1 mRNA

NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:18,285,934...18,499,819

G

regulatory factor X4

increases methylation

EXP

Glyphosate results in increased methylation of RFX4 gene

NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:20,741,079...20,902,851

G

regulatory factor X, 7

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RFX7 mRNA

NCBI chr 8:82,134,747...82,219,898
Ensembl chr 8:82,134,747...82,219,898

G

regulator of cell cycle

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RGCC gene

NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408

G

RGD1564712

affects methylation

EXP

Glyphosate affects the methylation of RGD1564712 gene

NCBI chr 4:79,983,114...80,010,594
Ensembl chr 4:79,983,114...80,010,484

G

regulator of G-protein signaling 16

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RGS16 mRNA

NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313

G

rhomboid domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of RHBDD1 gene

NCBI chr 9:91,076,786...91,196,719
Ensembl chr 9:91,078,210...91,196,850

G

rhomboid domain containing 3

increases methylation

EXP

Glyphosate results in increased methylation of RHBDD3 gene

NCBI chr14:84,208,155...84,214,334
Ensembl chr14:84,209,432...84,214,332

G

rhomboid like 2

decreases expression

EXP

Glyphosate results in decreased expression of RHBDL2 mRNA

NCBI chr 5:141,322,246...141,376,702
Ensembl chr 5:141,322,354...141,366,747

G

Rh blood group, D antigen

affects methylation

EXP

Glyphosate affects the methylation of RHD gene

NCBI chr 5:152,371,160...152,405,396
Ensembl chr 5:152,371,200...152,405,395

G

Rho-related BTB domain containing 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RHOBTB3 mRNA

NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906

G

ras homolog family member U

increases expression

ISO

Glyphosate results in increased expression of RHOU mRNA

NCBI chr19:68,538,960...68,548,733
Ensembl chr19:68,538,960...68,548,733

G

rhophilin, Rho GTPase binding protein 2

increases expression

ISO

Glyphosate results in increased expression of RHPN2 mRNA

NCBI chr 1:97,128,054...97,188,803
Ensembl chr 1:97,127,697...97,188,803

G

RIB43A domain with coiled-coils 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of RIBC2 mRNA

NCBI chr 7:118,122,722...118,137,772
Ensembl chr 7:118,122,408...118,137,767

G

reactive intermediate imine deaminase A homolog

increases methylation

EXP

Glyphosate results in increased methylation of RIDA gene

NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692

G

Rab interacting lysosomal protein-like 1

decreases methylation

EXP

Glyphosate results in decreased methylation of RILPL1 gene

NCBI chr12:37,732,847...37,770,659
Ensembl chr12:37,732,629...37,770,660

G

ribosomal modification protein rimK-like family member A

increases expression

ISO

Glyphosate results in increased expression of RIMKLA mRNA

NCBI chr 5:138,357,463...138,384,132
Ensembl chr 5:138,359,743...138,384,060

G

regulating synaptic membrane exocytosis 1

affects methylation

EXP

Glyphosate affects the methylation of RIMS1 gene

NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772

G

regulating synaptic membrane exocytosis 3

affects methylation

EXP

Glyphosate affects the methylation of RIMS3 gene

NCBI chr 5:139,714,302...139,754,145
Ensembl chr 5:139,714,320...139,754,145

G

regulating synaptic membrane exocytosis 4

affects methylation

EXP

Glyphosate affects the methylation of RIMS4 gene

NCBI chr 3:172,940,404...173,004,490
Ensembl chr 3:172,940,404...173,023,718

G

Ras and Rab interactor 3

decreases methylation

EXP

Glyphosate results in decreased methylation of RIN3 gene

NCBI chr 6:127,196,648...127,305,821
Ensembl chr 6:127,196,632...127,305,821

G

receptor interacting serine/threonine kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of RIPK1 mRNA

NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167

G

5.8S ribosomal RNA

affects methylation
increases expression

EXP

Glyphosate affects the methylation of RN5-8S gene
Glyphosate results in increased expression of RN5-8S mRNA

PMID:26302742 PMID:31011160

NCBI chr11:237,779...237,934
Ensembl chr11:237,781...237,933

G

RNA, 5S ribosomal 9

increases expression

EXP

Glyphosate results in increased expression of RN5S mRNA

NCBI chr19:68,507,561...68,507,679
Ensembl chr19:68,507,561...68,507,679

G

ribonuclease A family member 10

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RNASE10 gene

NCBI chr15:26,700,219...26,702,681
Ensembl chr15:26,688,102...26,706,105

G

ribonuclease A family member 12

decreases expression

EXP

Glyphosate results in decreased expression of RNASE12 mRNA

NCBI chr15:26,749,291...26,761,261
Ensembl chr15:26,749,291...26,750,326

G

Rho family GTPase 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RND3 gene; [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RND3 mRNA

NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:55,980,355...55,998,536

G

ring finger protein 144B

affects methylation

EXP

Glyphosate affects the methylation of RNF144B gene

PMID:31011160 PMID:35440735

NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,639,079...17,769,037

G

ring finger protein 220

affects methylation

EXP

Glyphosate affects the methylation of RNF220 gene

NCBI chr 5:135,975,739...136,198,017
Ensembl chr 5:135,975,739...136,197,858

G

ring finger protein 39

multiple interactions

ISO

[Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which affects the methylation of RNF39 promoter

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323

G

ribonuclease/angiogenin inhibitor 1

increases expression

ISO

Glyphosate results in increased expression of RNH1 protein

NCBI chr 1:205,698,882...205,711,348
Ensembl chr 1:205,698,882...205,711,582

G

renalase, FAD-dependent amine oxidase

affects methylation

EXP

Glyphosate affects the methylation of RNLS gene

NCBI chr 1:240,450,702...240,723,472
Ensembl chr 1:240,450,702...240,723,043

G

arginyl aminopeptidase like 1

increases expression

EXP

Glyphosate results in increased expression of RNPEPL1 mRNA

NCBI chr 9:100,921,053...100,933,748
Ensembl chr 9:100,923,856...100,933,485

G

RNA, U12 small nuclear

decreases expression

ISO

Glyphosate results in decreased expression of RNU12 mRNA

NCBI chr 7:116,183,590...116,183,740
Ensembl chr 7:116,183,590...116,183,740

G

RNA, U6 small nuclear 503

decreases expression

ISO

Glyphosate results in decreased expression of RNU6-998P mRNA

NCBI chr 2:234,436,952...234,437,058
Ensembl chr 2:234,436,952...234,437,058

G

RNA, U6 small nuclear 630

decreases expression

ISO

Glyphosate results in decreased expression of RNU6-1024P mRNA

NCBI chr 1:252,992,903...252,993,009
Ensembl chr 1:252,992,903...252,993,009

G

roundabout guidance receptor 1

affects methylation

EXP

Glyphosate affects the methylation of ROBO1 gene

NCBI chr11:24,067,869...25,108,694
Ensembl chr11:24,067,878...25,108,694

G

roundabout guidance receptor 2

affects methylation

EXP

Glyphosate affects the methylation of ROBO2 gene

NCBI chr11:26,015,919...27,583,750
Ensembl chr11:26,015,919...26,876,185

G

receptor tyrosine kinase-like orphan receptor 1

decreases expression

EXP

Glyphosate results in decreased expression of ROR1 mRNA

NCBI chr 5:119,859,744...120,203,573
Ensembl chr 5:119,859,970...120,205,801

G

RAR-related orphan receptor C

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RORC mRNA

NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566

G

replication protein A1

decreases expression

ISO

Glyphosate results in decreased expression of RPA1 mRNA

NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279

G

replication protein A2

decreases expression

ISO

Glyphosate results in decreased expression of RPA2 mRNA

NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546

G

ribosomal protein L10

increases expression

EXP

Glyphosate results in increased expression of RPL10 mRNA

NCBI chr X:157,205,850...157,208,057
Ensembl chr X:157,205,836...157,208,049

G

ribosomal protein L10, pseudogene 3

increases expression

EXP

Glyphosate results in increased expression of RPL10-PS3 mRNA

NCBI chr 3:81,031,281...81,032,231

G

ribosomal protein L10A

decreases expression

ISO

Glyphosate results in decreased expression of RPL10A protein

NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091

G

ribosomal protein L13

decreases expression

ISO

Glyphosate results in decreased expression of RPL13 protein

NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059

G

ribosomal protein L18

increases expression

EXP

Glyphosate results in increased expression of RPL18 mRNA

NCBI chr 1:105,325,269...105,327,911
Ensembl chr 1:105,325,250...105,327,910

G

ribosomal protein L19

decreases expression

ISO

Glyphosate results in decreased expression of RPL19 protein

NCBI chr10:83,514,509...83,522,352
Ensembl chr10:83,515,464...83,522,352

G

ribosomal protein L24

decreases expression

ISO

Glyphosate results in decreased expression of RPL24 protein

NCBI chr11:58,122,997...58,128,405
Ensembl chr11:58,122,997...58,128,405

G

ribosomal protein L28

decreases expression

ISO

Glyphosate results in decreased expression of RPL28 protein

NCBI chr 1:78,080,945...78,083,532
Ensembl chr 1:78,080,945...78,083,771

G

ribosomal protein L29 like 1

increases methylation

EXP

Glyphosate results in increased methylation of RPL29L1 gene

NCBI chr17:35,928,175...35,931,227

G

ribosomal protein L30

affects expression
increases expression

ISO
EXP

Glyphosate affects the expression of RPL30 protein
Glyphosate results in increased expression of RPL30 mRNA

PMID:20045496 PMID:26302742

NCBI chr 7:67,533,420...67,536,555
Ensembl chr 7:67,465,332...67,536,555

G

ribosomal protein L31

decreases expression

ISO

Glyphosate results in decreased expression of RPL31 mRNA

NCBI chr 9:49,143,044...49,147,155
Ensembl chr 9:49,142,955...49,147,155

G

ribosomal protein L35A

decreases expression

ISO

Glyphosate results in decreased expression of RPL35A protein

NCBI chr11:81,231,114...81,235,094
Ensembl chr 5:163,826,849...163,827,306
Ensembl chr11:163,826,849...163,827,306

G

ribosomal protein lateral stalk subunit P1, pseudogene 1

increases expression

EXP

Glyphosate results in increased expression of RPLP1-PS1 mRNA

NCBI chr 9:44,345,833...44,351,404

G

ribonuclease P/MRP subunit p30

affects methylation

EXP

Glyphosate affects the methylation of RPP30 gene

NCBI chr 1:243,198,647...243,221,559
Ensembl chr 1:243,198,713...243,221,553

G

ribonuclease P RNA component H1

increases expression

EXP

Glyphosate results in increased expression of RMRP mRNA

NCBI chr15:26,507,232...26,507,488
Ensembl chr15:26,507,215...26,507,512

G

ribosomal protein S12-like 12

increases expression

EXP

Glyphosate results in increased expression of RPS12L12 mRNA

NCBI chr 3:137,944,125...137,944,636
Ensembl chr 3:137,944,049...137,944,636

G

ribosomal protein S13

decreases expression

ISO

Glyphosate results in decreased expression of RPS13 mRNA; Glyphosate results in decreased expression of RPS13 protein

PMID:35897073 PMID:36173347

NCBI chr 1:180,007,230...180,009,660
Ensembl chr 1:180,002,471...180,009,660

G

ribosomal protein S16

increases expression

EXP

Glyphosate results in increased expression of RPS16 mRNA

NCBI chr 1:92,770,658...92,773,603
Ensembl chr19:56,922,246...56,923,020
Ensembl chr 1:56,922,246...56,923,020

G

ribosomal protein S2, pseudogene 10

decreases expression

EXP

Glyphosate results in decreased expression of RPS2-PS10 mRNA

G

ribosomal protein S21, pseudogene 1

increases expression

ISO

Glyphosate results in increased expression of RPS21 protein

NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490

G

ribosomal protein s25

increases expression

ISO

Glyphosate results in increased expression of RPS25 protein

NCBI chr 8:53,630,333...53,632,810
Ensembl chr 8:53,629,861...53,632,808
Ensembl chr 8:53,629,861...53,632,808

G

ribosomal protein S26

increases expression

ISO

Glyphosate results in increased expression of RPS26 protein

NCBI chr 7:1,641,846...1,643,404
Ensembl chr 7:1,641,421...1,643,399

G

ribosomal protein S27-like

increases expression

ISO

Glyphosate results in increased expression of RPS27L protein

NCBI chr 8:76,443,658...76,448,593
Ensembl chr12:33,713,661...33,714,130
Ensembl chr 8:33,713,661...33,714,130

G

ribosomal protein S28

increases expression

ISO

Glyphosate results in increased expression of RPS28 protein

NCBI chr 7:15,309,964...15,311,333
Ensembl chr16:72,591,164...72,591,373
Ensembl chr 7:72,591,164...72,591,373
Ensembl chr16:72,591,164...72,591,373

G

ribosomal protein S6 kinase B1

increases expression
decreases expression

ISO

Glyphosate results in increased expression of RPS6KB1 mRNA
Glyphosate results in decreased expression of RPS6KB1 mRNA

PMID:31295307 PMID:31874349

NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238

G

ribosomal protein S6 kinase C1

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of RPS6KC1 gene
Glyphosate affects the methylation of RPS6KC1 gene

PMID:31011160 PMID:35440735

NCBI chr13:104,877,296...105,021,490
Ensembl chr13:104,877,296...105,021,435

G

ribosomal protein S9, pseudogene 5

affects methylation

EXP

Glyphosate affects the methylation of RPS9-PS5 gene

NCBI chr 4:18,777,900...18,778,458

G

ribosomal protein S9, pseudogene 7

increases expression

EXP

Glyphosate results in increased expression of RPS9-PS7 mRNA

NCBI chr18:41,408,415...41,413,838

G

regulatory associated protein of MTOR, complex 1

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of RPTOR gene
Glyphosate results in decreased expression of RPTOR mRNA

PMID:31295307 PMID:35440735

NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413

G

RAS related

increases expression

ISO

Glyphosate results in increased expression of RRAS mRNA

NCBI chr 1:104,637,061...104,640,841
Ensembl chr 1:104,634,951...104,640,841

G

ribosome binding protein 1

increases expression

ISO

Glyphosate results in increased expression of RRBP1 protein

NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255

G

arginine and serine rich coiled-coil 1, pseudogene 3

decreases expression

EXP

Glyphosate results in decreased expression of RSRC1-PS3 mRNA

NCBI chr 1:46,046,121...46,047,237

G

Ras suppressor protein 1

affects methylation

EXP

Glyphosate affects the methylation of RSU1 gene

NCBI chr17:81,037,848...81,286,127
Ensembl chr17:81,042,595...81,286,030

G

RT1 class II, locus Bb

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of H2-AB1 mRNA

NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118

G

RT1 class II, locus Da

decreases expression

EXP

Glyphosate results in decreased expression of RT1-DA mRNA

NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383

G

RT1 class II, locus DMa

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of H2-DMA mRNA

NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335

G

RT1 class II, locus DMb

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of H2-DMB1 mRNA

NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246

G

RT1 class Ib, locus M3, gene 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of H2-M3 mRNA

NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366

G

rhotekin 2

increases expression

ISO

Glyphosate results in increased expression of RTKN2 mRNA

NCBI chr20:20,535,553...20,608,863
Ensembl chr20:20,535,553...20,608,899

G

receptor (chemosensory) transporter protein 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of RTP4 mRNA

NCBI chr11:90,741,992...90,840,061
Ensembl chr11:90,741,992...90,753,851

G

RUN and FYVE domain containing 4

increases methylation

EXP

Glyphosate results in increased methylation of RUFY4 gene

NCBI chr 9:83,152,139...83,172,683
Ensembl chr 9:83,154,445...83,172,897

G

RUNX family transcription factor 1

decreases expression

ISO

Glyphosate results in decreased expression of RUNX1 mRNA

NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925

G

RUNX1 partner transcriptional co-repressor 1

increases methylation

EXP

Glyphosate results in increased methylation of RUNX1T1 gene

NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:31,984,855...32,132,855

G

RUNX family transcription factor 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of RUNX3 mRNA

NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835

G

RUN and SH3 domain containing 2

increases methylation

EXP

Glyphosate results in increased methylation of RUSC2 gene

NCBI chr 5:62,424,185...62,471,317
Ensembl chr 5:62,444,665...62,471,314

G

RUS family member 1

increases methylation

EXP

Glyphosate results in increased methylation of RUSF1 gene

NCBI chr 1:192,282,708...192,312,119
Ensembl chr 1:192,282,711...192,311,137

G

RuvB-like AAA ATPase 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of RUVBL1 mRNA
Glyphosate results in increased expression of RUVBL1 protein

PMID:31295307 PMID:37208198

NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665

G

RuvB-like AAA ATPase 2

increases methylation

EXP

Glyphosate results in increased methylation of RUVBL2 gene

NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720

G

ribitol xylosyltransferase 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RXYLT1 gene

NCBI chr 7:59,656,274...59,668,140
Ensembl chr 7:59,656,276...59,668,050

G

receptor-like tyrosine kinase

decreases methylation

EXP

Glyphosate results in decreased methylation of RYK gene

NCBI chr 8:112,298,158...112,370,912
Ensembl chr 8:112,298,369...112,370,908

G

S100 calcium binding protein A13

increases expression

ISO

Glyphosate results in increased expression of S100A13 protein

NCBI chr 2:178,297,020...178,303,514
Ensembl chr 2:178,296,917...178,303,507

G

S100 calcium binding protein A6

increases expression

ISO

Glyphosate results in increased expression of S100A6 protein

PMID:20045496 PMID:24073338

NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762

G

S100 calcium binding protein A7A

increases expression

ISO

Glyphosate results in increased expression of S100A7A mRNA

NCBI chr 2:178,448,983...178,453,424
Ensembl chr 2:178,448,983...178,453,424

G

S100 calcium binding protein A9

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of S100A9 protein
Glyphosate results in decreased expression of S100A9 mRNA

PMID:20045496 PMID:24073338 PMID:38314887

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870

G

S100 calcium binding protein B

affects expression
decreases expression

EXP
ISO

Glyphosate affects the expression of S100B protein
Glyphosate results in decreased expression of S100B mRNA

PMID:28627408 PMID:33348142

NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081

G

spalt-like transcription factor 4

multiple interactions
decreases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SALL4 gene
Glyphosate results in decreased expression of SALL4 mRNA

PMID:30785197 PMID:33854195

NCBI chr 3:177,891,705...177,909,743
Ensembl chr 3:177,891,705...177,909,743

G

sterile alpha motif domain containing 4A

increases methylation

EXP

Glyphosate results in increased methylation of SAMD4A gene

NCBI chr15:22,616,200...22,831,872
Ensembl chr15:22,614,287...22,831,872

G

sterile alpha motif domain containing 7

decreases expression

EXP

Glyphosate results in decreased expression of SAMD7 mRNA

NCBI chr 2:114,551,633...114,572,774
Ensembl chr 2:114,551,640...114,572,774

G

Sin3A-associated protein 25

increases expression

EXP

Glyphosate results in increased expression of SAP25 mRNA

NCBI chr12:24,692,548...24,693,683

G

sarcosine dehydrogenase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SARDH mRNA

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137

G

SAM and SH3 domain containing 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of SASH3 mRNA

NCBI chr X:132,204,717...132,219,421
Ensembl chr X:132,204,543...132,219,419

G

secretory carrier membrane protein 2

decreases methylation

EXP

Glyphosate results in decreased methylation of SCAMP2 gene

NCBI chr 8:66,861,504...66,888,151
Ensembl chr 8:66,861,537...66,888,150

G

secretory carrier membrane protein 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of SCAMP4 mRNA

NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736

G

secretory carrier membrane protein 5

increases methylation

EXP

Glyphosate results in increased methylation of SCAMP5 gene

NCBI chr 8:66,739,794...66,778,538
Ensembl chr 8:66,741,940...66,751,099

G

S-phase cyclin A-associated protein in the ER

affects methylation

EXP

Glyphosate affects the methylation of SCAPER gene

NCBI chr 8:64,828,789...65,228,240
Ensembl chr 8:64,828,789...65,228,453

G

stearoyl-CoA desaturase

increases expression

ISO

Glyphosate results in increased expression of SCD1 mRNA

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

stearoyl-Coenzyme A desaturase 2

decreases expression

ISO

Glyphosate results in decreased expression of SCD2 mRNA

NCBI chr 1:253,118,377...253,131,436
Ensembl chr 1:253,117,655...253,128,874

G

sec1 family domain containing 2

increases methylation

EXP

Glyphosate results in increased methylation of SCFD2 gene

NCBI chr14:34,037,392...34,369,423
Ensembl chr14:34,037,430...34,363,436

G

secretogranin II

increases expression

ISO

Glyphosate results in increased expression of SCG2 mRNA

NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598

G

secretoglobin, family 1C, member 1

decreases expression

EXP

Glyphosate results in decreased expression of SCGB1C1 mRNA

NCBI chr 1:205,352,216...205,354,656
Ensembl chr 1:205,353,437...205,354,656

G

sodium channel and clathrin linker 1

affects methylation

EXP

Glyphosate affects the methylation of SCLT1 gene

NCBI chr 2:126,533,436...126,691,879
Ensembl chr 2:126,533,560...126,691,971

G

sodium channel epithelial 1 subunit alpha

multiple interactions
increases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SCNN1A mRNA
Glyphosate results in increased expression of SCNN1A mRNA

PMID:33854195 PMID:38314887

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405

G

sterol carrier protein 2

decreases expression

ISO

Glyphosate results in decreased expression of SCP2 protein

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043

G

SCP2 sterol-binding domain containing 1

increases expression

EXP

Glyphosate results in increased expression of SCP2D1 mRNA

NCBI chr 3:152,655,282...152,656,032
Ensembl chr 3:152,627,292...152,757,474

G

secernin 1

increases expression

ISO

Glyphosate results in increased expression of SCRN1 mRNA

NCBI chr 4:84,962,450...85,024,577
Ensembl chr 4:84,965,751...85,031,205

G

succinate dehydrogenase complex flavoprotein subunit A

increases expression

ISO

Glyphosate results in increased expression of SDHA mRNA; Glyphosate results in increased expression of SDHA protein

NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121

G

succinate dehydrogenase complex iron sulfur subunit B

decreases expression
increases methylation

ISO
EXP

Glyphosate results in decreased expression of SDHB mRNA
Glyphosate results in increased methylation of SDHB gene

PMID:31011160 PMID:37087751

NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667

G

succinate dehydrogenase complex subunit C

decreases expression

EXP

Glyphosate results in decreased expression of SDHC mRNA

NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044

G

sidekick cell adhesion molecule 2

decreases methylation

EXP

Glyphosate results in decreased methylation of SDK2 gene

NCBI chr10:99,324,047...99,601,683
Ensembl chr10:99,324,047...99,601,683

G

short chain dehydrogenase/reductase family 42E, member 1

multiple interactions
decreases expression

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SDR42E1 mRNA
Glyphosate results in decreased expression of SDR42E1 mRNA

PMID:33854195 PMID:38314887

NCBI chr19:62,624,130...62,636,652
Ensembl chr19:62,624,150...62,636,756

G

SEC16 homolog A, endoplasmic reticulum export factor

increases expression

ISO

Glyphosate results in increased expression of SEC16A protein

NCBI chr 3:29,627,779...29,662,925
Ensembl chr 3:29,627,779...29,662,319

G

Sec23 homolog A, COPII coat complex component

decreases expression

ISO

Glyphosate results in decreased expression of SEC23A protein

NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904

G

SEC24 homolog D, COPII coat complex component

increases methylation

EXP

Glyphosate results in increased methylation of SEC24D gene

NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:214,103,190...214,211,144

G

SEC61 translocon subunit alpha 1

decreases expression

ISO

Glyphosate results in decreased expression of SEC61A1 protein

NCBI chr 4:122,530,785...122,545,141
Ensembl chr 4:122,530,789...122,545,141

G

selenium binding protein 1

increases expression

ISO

Glyphosate results in increased expression of SELENBP1 protein

NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295

G

selectin P

affects methylation

EXP

Glyphosate affects the methylation of SELP gene

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987

G

SEM1 26S proteasome subunit

increases expression

EXP

Glyphosate results in increased expression of SEM1 mRNA

NCBI chr 4:35,638,306...35,658,462
Ensembl chr 4:35,638,306...35,658,462

G

semaphorin 5A

decreases expression

ISO

Glyphosate results in decreased expression of SEMA5A mRNA

NCBI chr 2:85,020,724...85,451,938
Ensembl chr 2:85,020,724...85,451,938

G

Sumo1/sentrin/SMT3 specific peptidase 18

affects methylation

EXP

Glyphosate affects the methylation of SENP18 gene

NCBI chr 4:162,752,390...162,753,817
Ensembl chr 4:162,750,058...162,754,014

G

SUMO specific peptidase 2

decreases expression

ISO

Glyphosate results in decreased expression of SENP2 mRNA

NCBI chr11:92,487,259...92,522,795
Ensembl chr11:92,485,931...92,522,735

G

stress-associated endoplasmic reticulum protein family member 2

decreases expression

ISO

Glyphosate results in decreased expression of SERP2 mRNA

NCBI chr15:58,289,148...58,313,224
Ensembl chr15:58,289,148...58,313,430

G

serpin family A member 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SERPINA1 mRNA

NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703

G

serpin family A member 3N

increases expression

ISO

Glyphosate results in increased expression of SERPINA3N mRNA

NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415

G

serpin family A member 5

decreases expression

ISO

Glyphosate results in decreased expression of SERPINA5 mRNA

NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:128,784,991...128,793,186

G

serpin family A member 9

increases methylation

EXP

Glyphosate results in increased methylation of SERPINA9 gene

NCBI chr 6:128,683,650...128,700,784
Ensembl chr 6:128,683,664...128,700,784

G

serpin family D member 1

increases expression

ISO

Glyphosate results in increased expression of SERPIND1 mRNA

NCBI chr11:97,168,753...97,179,830
Ensembl chr11:97,168,754...97,179,755

G

serpin family G member 1

affects methylation

EXP

Glyphosate affects the methylation of SERPING1 gene

NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717

G

SERTA domain containing 2

decreases methylation

EXP

Glyphosate results in decreased methylation of SERTAD2 gene

NCBI chr14:98,935,428...99,039,536
Ensembl chr14:98,934,769...99,041,468

G

serine-rich and transmembrane domain containing 1

decreases expression

EXP

Glyphosate results in decreased expression of SERTM1 mRNA

NCBI chr 2:141,237,054...141,256,669
Ensembl chr 2:141,235,409...141,265,984

G

sestrin 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA

NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255

G

SEC14 and spectrin domain containing 1

affects methylation

EXP

Glyphosate affects the methylation of SESTD1 gene

NCBI chr 3:82,530,796...82,627,960
Ensembl chr 3:82,537,092...82,588,078

G

SET domain containing 2, histone lysine methyltransferase

affects methylation

EXP

Glyphosate affects the methylation of SETD2 gene

NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863

G

SET domain containing 6, protein lysine methyltransferase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA

NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515

G

SET domain bifurcated histone lysine methyltransferase 1

increases expression

EXP

Glyphosate results in increased expression of SETDB1 mRNA

NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:185,587,722...185,618,982

G

splicing factor 3A subunit 1

increases expression

EXP

Glyphosate results in increased expression of SF3A1 mRNA

NCBI chr14:83,254,971...83,275,720
Ensembl chr14:83,254,971...83,275,720

G

splicing factor 3a, subunit 3

decreases expression

ISO

Glyphosate results in decreased expression of SF3A3 protein

NCBI chr 5:142,246,556...142,272,053
Ensembl chr 5:142,246,568...142,272,052

G

splicing factor 3b, subunit 2

affects methylation

ISO

Glyphosate affects the methylation of SF3B2 gene

NCBI chr 1:211,999,777...212,040,686
Ensembl chr 1:211,999,778...212,020,113

G

splicing factor 3b, subunit 5

increases expression

EXP

Glyphosate results in increased expression of SF3B5 mRNA

NCBI chr 1:9,177,189...9,177,901
Ensembl chr 1:9,177,098...9,177,900

G

secreted frizzled-related protein 1

decreases expression

EXP

Glyphosate results in decreased expression of SFRP1 mRNA

NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736

G

secreted frizzled-related protein 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SFRP2 gene

NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079

G

secreted frizzled-related protein 4

decreases expression

EXP

Glyphosate results in decreased expression of SFRP4 mRNA

NCBI chr17:49,974,532...50,026,448
Ensembl chr17:50,015,812...50,026,395

G

SFT2 domain containing 2

decreases methylation

EXP

Glyphosate results in decreased methylation of SFT2D2 gene

NCBI chr13:80,017,854...80,037,144
Ensembl chr13:80,008,480...80,037,473

G

serum/glucocorticoid regulated kinase 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of SGK1 mRNA
Glyphosate results in increased expression of SGK1 mRNA

PMID:31295307 PMID:35897073

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231

G

serum/glucocorticoid regulated kinase family, member 3

decreases expression

ISO

Glyphosate results in decreased expression of SGK3 mRNA

NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:14,126,257...14,198,331

G

sphingomyelin synthase 1

affects methylation

EXP

Glyphosate affects the methylation of SGMS1 gene

NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774

G

SH3-domain binding protein 2

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SH3BP2 mRNA
Glyphosate results in increased expression of SH3BP2 mRNA

PMID:33854195 PMID:35897073

NCBI chr14:80,400,685...80,437,887
Ensembl chr14:80,400,685...80,437,906

G

SH3 domain containing GRB2 like 3, endophilin A3

affects methylation

EXP

Glyphosate affects the methylation of SH3GL3 gene

NCBI chr 1:145,533,728...145,664,881
Ensembl chr 1:145,533,728...145,664,881

G

SH3 and PX domains 2B

increases expression

ISO

Glyphosate results in increased expression of SH3PXD2B mRNA

NCBI chr10:17,422,906...17,538,977
Ensembl chr10:17,422,947...17,512,854

G

SH3 domain containing ring finger 1

increases methylation

EXP

Glyphosate results in increased methylation of SH3RF1 gene

NCBI chr16:33,746,396...33,912,127
Ensembl chr16:33,746,396...33,912,153

G

SH3 domain containing ring finger 2

increases expression

ISO

Glyphosate results in increased expression of SH3RF2 mRNA

NCBI chr18:34,296,753...34,397,880
Ensembl chr18:34,296,733...34,397,876

G

SH3 and multiple ankyrin repeat domains 3

increases methylation

EXP

Glyphosate results in increased methylation of SHANK3 gene

NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:122,448,323...122,510,410

G

SH2 domain containing adaptor protein B

affects methylation

EXP

Glyphosate affects the methylation of SHB gene

NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072

G

sex hormone binding globulin

decreases expression

ISO

Glyphosate results in decreased expression of SHBG mRNA

NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760

G

SHC adaptor protein 4

decreases expression

ISO

Glyphosate results in decreased expression of SHC4 mRNA

NCBI chr 3:133,334,026...133,428,404
Ensembl chr 3:133,334,034...133,427,826

G

sonic hedgehog signaling molecule

increases expression

EXP

Glyphosate results in increased expression of SHH mRNA

NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901

G

shieldin complex subunit 1

increases methylation

EXP

Glyphosate results in increased methylation of SHLD1 gene

NCBI chr 3:140,391,611...140,462,273
Ensembl chr 3:140,389,220...140,462,609

G

serine hydroxymethyltransferase 2

increases expression

ISO

Glyphosate results in increased expression of SHMT2 protein

NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567

G

siah E3 ubiquitin protein ligase 1

increases expression

ISO

Glyphosate results in increased expression of SIAH1 mRNA

NCBI chr19:36,552,165...36,575,773
Ensembl chr19:36,540,947...36,581,541

G

single Ig and TIR domain containing

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SIGIRR mRNA

NCBI chr 1:205,625,742...205,637,883
Ensembl chr 1:205,627,708...205,637,802

G

salt-inducible kinase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SIK2 mRNA

NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:60,121,913...60,221,818

G

signal-induced proliferation-associated 1 like 2

increases expression

ISO

Glyphosate results in increased expression of SIPA1L2 mRNA

NCBI chr19:70,287,134...70,437,810
Ensembl chr19:70,287,147...70,437,773

G

signal-induced proliferation-associated 1 like 3

affects methylation

EXP

Glyphosate affects the methylation of SIPA1L3 gene

NCBI chr 1:93,746,187...93,953,606
Ensembl chr 1:93,746,192...93,831,268

G

signal-regulatory protein alpha like 1

affects methylation

EXP

Glyphosate affects the methylation of SIRPAL1 gene

NCBI chr 2:87,238,681...87,427,498
Ensembl chr 2:87,934,273...87,989,800

G

signal-regulatory protein beta 3

increases expression

EXP

Glyphosate results in increased expression of SIRPB3 mRNA

NCBI chr 3:137,131,945...137,216,434
Ensembl chr 3:137,133,164...137,216,434

G

SIX homeobox 3

increases expression

ISO

Glyphosate results in increased expression of SIX3 mRNA

NCBI chr 6:14,791,937...14,796,365
Ensembl chr 6:14,789,354...14,804,175

G

spindle and kinetochore associated complex subunit 1

increases expression

EXP

Glyphosate results in increased expression of SKA1 mRNA

NCBI chr18:70,069,957...70,080,303
Ensembl chr18:70,069,957...70,080,398

G

src kinase associated phosphoprotein 1

increases methylation

EXP

Glyphosate results in increased methylation of SKAP1 gene

NCBI chr10:81,921,961...82,229,106
Ensembl chr10:81,921,980...82,229,105

G

SKI-like proto-oncogene

affects methylation

EXP

Glyphosate affects the methylation of SKIL gene

NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:114,175,534...114,201,974

G

S-phase kinase associated protein 2

decreases expression

ISO

Glyphosate results in decreased expression of SKP2 mRNA

NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:59,888,413...59,916,438

G

SLAM family member 8

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of SLAMF8 mRNA

NCBI chr13:87,580,081...87,589,941
Ensembl chr13:87,580,182...87,589,560

G

solute carrier family 12 member 1

increases methylation
decreases expression

EXP

Glyphosate results in increased methylation of SLC12A1 gene
Glyphosate results in decreased expression of SLC12A1 mRNA

PMID:31011160 PMID:37001608

NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340

G

solute carrier family 12, member 6

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC12A6 mRNA

NCBI chr 3:119,525,521...119,624,655
Ensembl chr 3:119,526,295...119,624,653

G

solute carrier family 12, member 9

decreases methylation

EXP

Glyphosate results in decreased methylation of SLC12A9 gene

NCBI chr12:25,005,741...25,022,628
Ensembl chr12:25,005,738...25,022,607

G

solute carrier family 13 member 3

decreases methylation

EXP

Glyphosate results in decreased methylation of SLC13A3 gene

NCBI chr 3:174,561,174...174,623,893
Ensembl chr 3:174,561,168...174,623,895

G

solute carrier family 14 member 1 (Kidd blood group)

decreases expression

EXP

Glyphosate results in decreased expression of SLC14A1 mRNA

NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489

G

solute carrier family 16 member 2

affects expression
multiple interactions
increases expression

EXP
ISO

Glyphosate affects the expression of SLC16A2 mRNA
Melatonin inhibits the reaction [Glyphosate affects the expression of SLC16A2 mRNA]
Glyphosate results in increased expression of SLC16A2 mRNA

PMID:27916585 PMID:33159990 PMID:33512083

NCBI chr X:72,791,096...72,914,299
Ensembl chr X:72,781,876...72,914,498

G

solute carrier family 17 member 6

decreases expression

EXP

Glyphosate results in decreased expression of SLC17A6 mRNA

NCBI chr 1:110,348,447...110,388,499
Ensembl chr 1:110,348,447...110,388,498

G

solute carrier family 17 member 8

decreases expression

ISO

Glyphosate results in decreased expression of SLC17A8 mRNA

NCBI chr 7:25,881,557...25,936,837
Ensembl chr 7:25,881,557...25,935,410

G

solute carrier family 20 member 1

multiple interactions
decreases methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC20A1 mRNA
Glyphosate results in decreased methylation of SLC20A1 gene

PMID:31011160 PMID:33854195

NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249

G

solute carrier family 22 member 2

increases expression

ISO

Glyphosate results in increased expression of SLC22A2 mRNA

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019

G

solute carrier family 22 member 20

increases methylation

EXP

Glyphosate results in increased methylation of SLC22A20 gene

NCBI chr 1:212,686,691...212,703,163
Ensembl chr 1:212,686,691...212,703,163

G

solute carrier family 22, member 23

affects expression

EXP

Glyphosate affects the expression of SLC22A23 mRNA

NCBI chr17:30,749,445...30,915,139
Ensembl chr17:30,749,445...30,915,139

G

solute carrier family 24 member 4

affects methylation

EXP

Glyphosate affects the methylation of SLC24A4 gene

NCBI chr 6:127,044,470...127,184,684
Ensembl chr 6:127,044,470...127,184,684

G

solute carrier family 25 member 3

decreases expression

ISO

Glyphosate results in decreased expression of SLC25A3 mRNA

NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309

G

solute carrier family 25 member 33

increases expression

ISO

Glyphosate results in increased expression of SLC25A33 mRNA

NCBI chr 5:165,478,070...165,518,186
Ensembl chr 5:165,478,072...165,502,973

G

solute carrier family 25, member 39

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC25A39 mRNA

NCBI chr10:87,862,630...87,867,626
Ensembl chr10:87,862,631...87,866,973

G

solute carrier family 26 member 6

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC26A6 mRNA

NCBI chr 8:118,438,110...118,448,271
Ensembl chr 8:118,438,180...118,448,270

G

solute carrier family 28 member 1

affects methylation

EXP

Glyphosate affects the methylation of SLC28A1 gene

NCBI chr 1:144,490,453...144,532,025
Ensembl chr 1:144,490,623...144,531,544

G

solute carrier family 28 member 2

affects methylation

EXP

Glyphosate affects the methylation of SLC28A2 gene

NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291

G

solute carrier family 29 member 3

affects methylation

EXP

Glyphosate affects the methylation of SLC29A3 gene

NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299

G

solute carrier family 2 member 1

increases expression

ISO

Glyphosate results in increased expression of SLC2A1 mRNA
Glyphosate results in increased expression of SLC2A1 protein

PMID:30605748 PMID:36572786

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742

G

solute carrier family 2 member 4

decreases expression

EXP

Glyphosate results in decreased expression of SLC2A4 mRNA

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270

G

solute carrier family 2 member 9

affects expression

EXP

Glyphosate affects the expression of SLC2A9 mRNA

NCBI chr14:76,540,649...76,674,277
Ensembl chr14:76,540,571...76,674,277

G

solute carrier family 30 member 8

increases expression

EXP

Glyphosate results in increased expression of SLC30A8 mRNA

NCBI chr 7:85,481,864...85,517,255
Ensembl chr 7:85,481,864...85,517,177

G

solute carrier family 31 member 2

decreases expression

EXP

Glyphosate results in decreased expression of SLC31A2 mRNA

NCBI chr 5:80,753,589...80,764,126
Ensembl chr 5:80,753,618...80,764,123

G

solute carrier family 35, member D3

increases expression

ISO

Glyphosate results in increased expression of SLC35D3 mRNA

NCBI chr 1:16,389,308...16,392,780
Ensembl chr 1:16,389,308...16,392,780

G

solute carrier family 37 member 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC37A2 mRNA

NCBI chr 8:45,134,596...45,160,551
Ensembl chr 8:45,134,596...45,277,989

G

solute carrier family 38, member 11

affects methylation
multiple interactions

EXP
ISO

Glyphosate affects the methylation of SLC38A11 gene
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of SLC38A11 mRNA

PMID:35440735 PMID:37567420

NCBI chr 3:70,374,550...70,442,313
Ensembl chr 3:70,395,233...70,441,712

G

solute carrier family 38, member 2

increases expression

ISO

Glyphosate results in increased expression of SLC38A2 mRNA

NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619

G

solute carrier family 39, member 11

affects methylation

EXP

Glyphosate affects the methylation of SLC39A11 gene

NCBI chr10:98,775,155...99,196,302
Ensembl chr10:98,776,525...99,107,368

G

solute carrier family 39 member 5

increases expression

EXP

Glyphosate results in increased expression of SLC39A5 mRNA

NCBI chr 7:1,409,360...1,415,407
Ensembl chr 7:1,409,360...1,414,784

G

solute carrier family 44, member 3

affects methylation
decreases methylation

EXP

Glyphosate affects the methylation of SLC44A3 gene
Glyphosate results in decreased methylation of SLC44A3 gene

PMID:31011160 PMID:35440735

NCBI chr 2:212,234,425...212,312,886
Ensembl chr 2:212,236,853...212,312,982

G

solute carrier family 44, member 4

increases methylation

EXP

Glyphosate results in increased methylation of SLC44A4 gene

NCBI chr20:3,907,737...3,923,911
Ensembl chr20:3,907,737...3,923,854

G

solute carrier family 44, member 5

affects methylation

EXP

Glyphosate affects the methylation of SLC44A5 gene

NCBI chr 2:245,570,875...245,866,369
Ensembl chr 2:245,570,829...245,867,780

G

solute carrier family 45, member 1

decreases methylation

EXP

Glyphosate results in decreased methylation of SLC45A1 gene

NCBI chr 5:166,388,115...166,412,183
Ensembl chr 5:166,388,115...166,412,183

G

solute carrier family 45, member 3

increases expression

ISO

Glyphosate results in increased expression of SLC45A3 mRNA

NCBI chr13:45,959,467...45,979,763
Ensembl chr13:45,959,467...45,979,763

G

solute carrier family 4 member 8

increases methylation

EXP

Glyphosate results in increased methylation of SLC4A8 gene

NCBI chr 7:133,742,830...133,818,056
Ensembl chr 7:133,742,830...133,818,056

G

solute carrier family 5 member 2

increases expression

EXP

Glyphosate results in increased expression of SLC5A2 mRNA

NCBI chr 1:192,277,621...192,283,742
Ensembl chr 1:192,277,621...192,283,742

G

solute carrier family 5 member 3

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of SLC5A3 mRNA
Glyphosate results in decreased expression of SLC5A3 mRNA

PMID:35897073 PMID:38314887

NCBI chr11:44,799,787...44,802,233
Ensembl chr11:44,790,297...44,818,157

G

solute carrier family 5 member 5

increases expression
multiple interactions
decreases expression

EXP
ISO

Glyphosate results in increased expression of SLC5A5 mRNA
Melatonin inhibits the reaction [Glyphosate results in decreased expression of NIS mRNA]

PMID:33159990 PMID:36462676

NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691

G

solute carrier family 6 member 17

affects methylation

EXP

Glyphosate affects the methylation of SLC6A17 gene

NCBI chr 2:197,795,622...197,843,883
Ensembl chr 2:197,795,622...197,843,883

G

solute carrier family 6 member 3

increases expression

ISO

Glyphosate results in increased expression of SLC6A3 mRNA

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962

G

solute carrier family 6 member 4

decreases expression

ISO

Glyphosate results in decreased expression of SLC6A4 mRNA

NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056

G

solute carrier family 6 member 8

increases expression

ISO

Glyphosate results in increased expression of SLC6A8 mRNA

NCBI chr X:156,536,017...156,545,321
Ensembl chr X:156,536,017...156,545,321

G

solute carrier family 6 member 9

increases methylation

EXP

Glyphosate results in increased methylation of SLC6A9 gene

NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 15

decreases expression

EXP

Glyphosate results in decreased expression of SLC7A15 mRNA

NCBI chr 6:37,123,019...37,135,601
Ensembl chr 6:37,123,019...37,134,501

G

solute carrier family 7 member 3

decreases expression

EXP

Glyphosate results in decreased expression of SLC7A3 mRNA

NCBI chr X:70,250,089...70,256,610
Ensembl chr X:70,250,099...70,256,059

G

solute carrier family 7 member 7

decreases expression

EXP

Glyphosate results in decreased expression of SLC7A7 mRNA

NCBI chr15:31,792,122...31,852,732
Ensembl chr15:31,792,125...31,835,683

G

solute carrier organic anion transporter family, member 1a4

decreases methylation

EXP

Glyphosate results in decreased methylation of SLCO1A2 gene

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816

G

solute carrier organic anion transporter family, member 1a8

increases methylation

EXP

Glyphosate results in increased methylation of SLCO1A8 gene

NCBI chr 4:176,706,205...176,749,723
Ensembl chr 4:176,706,208...176,745,669

G

solute carrier organic anion transporter family, member 1c1

affects expression

EXP

Glyphosate affects the expression of SLCO1C1 mRNA

NCBI chr 4:176,197,736...176,244,401
Ensembl chr 4:176,197,741...176,244,395

G

solute carrier organic anion transporter family, member 3a1

increases expression

ISO

Glyphosate results in increased expression of SLCO3A1 mRNA

NCBI chr 1:137,516,037...137,797,836
Ensembl chr 1:137,505,158...137,797,836

G

solute carrier organic anion transporter family, member 4a1

increases methylation

EXP

Glyphosate results in increased methylation of SLCO4A1 gene

NCBI chr 3:187,936,735...187,955,873
Ensembl chr 3:187,936,820...187,955,871

G

schlafen family member 9

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of SLFN9 mRNA

NCBI chr10:68,406,641...68,420,062
Ensembl chr10:68,406,642...68,421,134

G

slit guidance ligand 1

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of SLIT1 gene
Glyphosate results in decreased expression of SLIT1 mRNA

PMID:35440735 PMID:38314887

NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476

G

slit guidance ligand 3

increases methylation

EXP

Glyphosate results in increased methylation of SLIT3 gene

NCBI chr10:20,075,929...20,660,704
Ensembl chr10:20,076,021...20,660,704

G

STE20-like kinase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SLK gene

NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829

G

SLU7 homolog, splicing factor

increases methylation

EXP

Glyphosate results in increased methylation of SLU7 gene

NCBI chr10:28,406,908...28,425,253
Ensembl chr10:28,409,846...28,425,250

G

SMAD family member 1

decreases expression

ISO

Glyphosate results in decreased expression of SMAD1 mRNA

NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957

G

SMAD family member 3

decreases expression

ISO

Glyphosate results in decreased expression of SMAD3 mRNA

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324

G

SMAD family member 4

increases expression

ISO

Glyphosate results in increased expression of SMAD4 mRNA

NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684

G

SMAD family member 7

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849

G

small cell adhesion glycoprotein

affects methylation

EXP

Glyphosate affects the methylation of SMAGP gene

NCBI chr 7:133,599,043...133,617,492
Ensembl chr 7:133,599,043...133,616,642

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

increases expression

EXP

Glyphosate results in increased expression of SMARCB1 mRNA

NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

decreases expression

ISO

Glyphosate results in decreased expression of SMARCC1 protein

NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:118,989,516...119,093,152

G

structural maintenance of chromosomes 1A

decreases expression

ISO

Glyphosate results in decreased expression of SMC1A mRNA

NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462

G

structural maintenance of chromosomes 1B

decreases expression

ISO

Glyphosate results in decreased expression of SMC1B mRNA

NCBI chr 7:118,060,898...118,122,683
Ensembl chr 7:118,060,156...118,122,648

G

single-pass membrane protein with coiled-coil domains 3

increases expression

ISO

Glyphosate results in increased expression of SMCO3 mRNA

NCBI chr 4:171,451,165...171,453,036
Ensembl chr 4:171,427,002...171,459,592

G

sperm mitochondria-associated cysteine-rich protein

increases expression

EXP

Glyphosate results in increased expression of SMCP mRNA

NCBI chr 2:180,856,561...180,861,564

G

small integral membrane protein 17

increases expression

ISO

Glyphosate results in increased expression of SMIM17 mRNA

NCBI chr 1:76,475,371...76,523,288
Ensembl chr 1:76,477,804...76,496,035

G

small integral membrane protein 44

decreases expression

EXP

Glyphosate results in decreased expression of SMIM44 mRNA

NCBI chr 7:8,968,893...8,970,123
Ensembl chr 7:8,968,893...8,970,123

G

SPARC related modular calcium binding 1

increases expression

ISO

Glyphosate results in increased expression of SMOC1 mRNA

NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956

G

sperm motility kinase like 3

increases expression

EXP

Glyphosate results in increased expression of SMOKL3 mRNA

NCBI chr 7:16,444,929...16,460,250
Ensembl chr 7:16,438,896...17,100,735

G

small muscle protein, X-linked

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SMPX gene

NCBI chr X:41,049,354...41,107,323
Ensembl chr X:41,049,356...41,107,137

G

synuclein alpha

increases expression

ISO

Glyphosate results in increased expression of SNCA mRNA

NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315

G

small nucleolar RNA host gene 4 (non-protein coding)

decreases expression

EXP

Glyphosate results in decreased expression of SNHG4 mRNA

NCBI chr18:27,432,526...27,432,762

G

small nucleolar RNA, H/ACA box 58

increases expression

EXP

Glyphosate results in increased expression of MIR3068 mRNA

NCBI chr 6:112,811,875...112,811,950

G

small nucleolar RNA, H/ACA box 5A

increases expression

ISO

Glyphosate results in increased expression of SNORA5A mRNA

NCBI chr14:85,700,633...85,700,761
Ensembl chr14:85,700,633...85,700,761

G

small nucleolar RNA, C/D box 20

decreases expression

ISO

Glyphosate results in decreased expression of SNORD20 mRNA

NCBI chr 9:94,449,039...94,449,118
Ensembl chr 9:94,449,039...94,449,118

G

small nuclear ribonucleoprotein U5 subunit 200

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SNRNP200 mRNA

NCBI chr 3:134,882,173...134,911,512
Ensembl chr 3:134,882,173...134,911,500

G

small nuclear ribonucleoprotein U1 subunit 70

decreases expression

ISO

Glyphosate results in decreased expression of SNRNP70 protein

NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851

G

syntrophin, beta 1

affects methylation

EXP

Glyphosate affects the methylation of SNTB1 gene

NCBI chr 7:88,950,642...89,219,017
Ensembl chr 7:88,950,642...89,219,017

G

syntrophin, beta 2

affects methylation

EXP

Glyphosate affects the methylation of SNTB2 gene

NCBI chr19:51,739,492...51,832,083
Ensembl chr19:51,741,183...51,823,872

G

SNW domain containing 1

increases expression

ISO

Glyphosate results in increased expression of SNW1 mRNA

NCBI chr 6:112,826,374...112,850,459
Ensembl chr 6:112,826,381...112,858,180

G

sorting nexin family member 30

increases expression

ISO

Glyphosate results in increased expression of SNX30 mRNA

NCBI chr 5:79,478,804...79,608,118
Ensembl chr 5:79,478,912...79,607,052

G

sorting nexin 4

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA

NCBI chr11:80,965,965...81,023,234
Ensembl chr11:80,965,967...81,028,448

G

suppressor of cytokine signaling 2

decreases expression

ISO

Glyphosate results in decreased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423

G

suppressor of cytokine signaling 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SOCS3 mRNA

NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825

G

suppressor of cytokine signaling 4

decreases expression

ISO

Glyphosate results in decreased expression of SOCS4 mRNA

NCBI chr15:23,003,130...23,017,615
Ensembl chr15:23,002,883...23,022,499

G

suppressor of cytokine signaling 5

decreases expression

ISO

Glyphosate results in decreased expression of SOCS5 mRNA

NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883

G

superoxide dismutase 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of SOD1 protein
Glyphosate results in increased expression of SOD1 mRNA

PMID:20045496 PMID:24073338 PMID:33348142

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

decreases expression
multiple interactions
increases expression

EXP
ISO

Glyphosate results in decreased expression of SOD2 protein
NOX1 protein affects the reaction [Glyphosate results in decreased expression of SOD2 protein]
Glyphosate results in increased expression of SOD2 mRNA

PMID:31352102 PMID:34906888

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

superoxide dismutase 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SOD3 mRNA

NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125

G

spermatogenesis and oogenesis specific basic helix-loop-helix 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SOHLH1 gene

NCBI chr 3:29,061,267...29,065,588
Ensembl chr 3:29,061,267...29,065,588

G

spermatogenesis and oogenesis specific basic helix-loop-helix 2

increases expression

ISO

Glyphosate results in increased expression of SOHLH2 mRNA

NCBI chr 2:141,512,410...141,534,864
Ensembl chr 2:141,512,293...141,534,863

G

sortilin-related VPS10 domain containing receptor 2

affects methylation

EXP

Glyphosate affects the methylation of SORCS2 gene

NCBI chr14:78,592,290...78,960,582
Ensembl chr14:78,596,087...78,960,582

G

sortilin-related VPS10 domain containing receptor 3

affects methylation

EXP

Glyphosate affects the methylation of SORCS3 gene

NCBI chr 1:257,040,442...257,675,259
Ensembl chr 1:257,040,473...257,675,259

G

SOS Ras/Rac guanine nucleotide exchange factor 1

increases expression
decreases expression

ISO

Glyphosate results in increased expression of SOS1 mRNA
Glyphosate results in decreased expression of SOS1 mRNA

PMID:31295307 PMID:35897073

NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350

G

sclerostin domain containing 1

decreases expression

EXP

Glyphosate results in decreased expression of SOSTDC1 mRNA

NCBI chr 6:58,778,623...58,782,797
Ensembl chr 6:58,778,623...58,782,866

G

SRY-box transcription factor 11

decreases expression

EXP

Glyphosate results in decreased expression of SOX11 mRNA

NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:49,736,304...49,738,691

G

SRY-box transcription factor 5

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of SOX5 gene
Glyphosate affects the methylation of SOX5 gene

PMID:31011160 PMID:35440735

NCBI chr 4:178,512,272...179,467,686
Ensembl chr 4:178,512,272...178,938,495

G

SRY-box transcription factor 9

decreases expression

ISO

Glyphosate results in decreased expression of SOX9 mRNA

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

Sp1 transcription factor

increases expression

ISO

Glyphosate results in increased expression of SP1 mRNA

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

sperm acrosome associated 9

multiple interactions
decreases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of SPACA9 mRNA
Glyphosate results in decreased expression of SPACA9 mRNA

PMID:37567420 PMID:38314887

NCBI chr 3:32,417,350...32,426,776
Ensembl chr 3:32,417,350...32,426,934

G

sperm associated antigen 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SPAG1 mRNA

NCBI chr 7:69,246,301...69,306,483
Ensembl chr 7:69,246,582...69,306,482

G

sperm associated antigen 17

increases expression

ISO

Glyphosate results in increased expression of SPAG17 mRNA

NCBI chr 2:189,952,649...190,199,623
Ensembl chr 2:189,952,729...190,189,755

G

sperm associated antigen 6

decreases expression

EXP

Glyphosate results in decreased expression of SPAG6 mRNA

NCBI chr17:86,258,418...86,309,922
Ensembl chr17:86,262,000...86,309,909

G

spermatogenesis associated 17

increases methylation
decreases expression

EXP

Glyphosate results in increased methylation of SPATA17 gene
Glyphosate results in decreased expression of SPATA17 mRNA

PMID:31011160 PMID:38314887

NCBI chr13:101,137,415...101,316,221
Ensembl chr13:101,137,415...101,316,376

G

spermatogenesis associated, serine-rich 1

increases methylation

EXP

Glyphosate results in increased methylation of SPATS1 gene

NCBI chr 9:23,024,129...23,059,734
Ensembl chr 9:23,024,609...23,059,730

G

sperm antigen with calponin homology and coiled-coil domains 1

affects methylation

EXP

Glyphosate affects the methylation of SPECC1 gene

NCBI chr10:47,138,351...47,412,311
Ensembl chr10:47,138,398...47,412,319

G

spermatogenesis associated glutamate (E)-rich protein 4C like 1

increases expression

EXP

Glyphosate results in increased expression of SPEER4CL1 mRNA

NCBI chr19:24,811,769...25,016,336

G

spermatogenesis associated glutamate (E)-rich protein 4C like 6

increases expression

EXP

Glyphosate results in increased expression of SPEER4CL6 mRNA

NCBI chr19:17,695,338...17,700,088
Ensembl chr19:28,675,864...28,727,848
Ensembl chr19:28,675,864...28,727,848

G

Spetex-2F protein

increases methylation

EXP

Glyphosate results in increased methylation of SPETEX2F gene

NCBI chr15:5,457,458...5,460,606
Ensembl chr15:5,456,826...5,470,118
Ensembl chr15:5,456,826...5,470,118

G

serine peptidase inhibitor Kazal type 13

decreases expression

ISO

Glyphosate results in decreased expression of SPINK13 mRNA

NCBI chr18:58,335,146...58,476,569
Ensembl chr18:58,335,146...58,476,569

G

serine peptidase inhibitor, Kazal type 8

decreases expression

ISO

Glyphosate results in decreased expression of SPINK8 mRNA

NCBI chr 8:118,686,362...118,707,449
Ensembl chr 8:118,686,366...118,707,544

G

SPNS lysolipid transporter 3, sphingosine-1-phosphate

increases methylation

EXP

Glyphosate results in increased methylation of SPNS3 gene

NCBI chr10:57,612,796...57,667,601
Ensembl chr10:57,612,819...57,667,414

G

speckle type BTB/POZ protein

decreases expression

ISO

Glyphosate results in decreased expression of SPOP mRNA

NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,854,973...80,935,146

G

secreted phosphoprotein 1

decreases expression

EXP

Glyphosate results in decreased expression of SPP1 mRNA

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

sprouty RTK signaling antagonist 1

affects methylation

EXP

Glyphosate affects the methylation of SPRY1 gene

NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:122,484,355...122,492,956

G

splA/ryanodine receptor domain and SOCS box containing 1

increases expression

ISO

Glyphosate results in increased expression of SPSB1 mRNA

NCBI chr 5:165,641,255...165,701,482
Ensembl chr 5:165,642,851...165,654,225

G

serine palmitoyltransferase, long chain base subunit 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of SPTLC3 mRNA

NCBI chr 3:147,301,570...147,431,696
Ensembl chr 3:147,301,801...147,434,044

G

steroid 5 alpha-reductase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SRD5A2 gene

NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:27,178,079...27,217,588

G

sterol regulatory element binding transcription factor 1

increases expression

ISO

Glyphosate results in increased expression of SREBF1 mRNA

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

sterol regulatory element binding transcription factor 2

increases expression

ISO

Glyphosate results in increased expression of SREBF2 mRNA

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943

G

splicing regulatory glutamic acid and lysine rich protein 1

increases expression

EXP

Glyphosate results in increased expression of SREK1 mRNA

NCBI chr 2:36,583,412...36,618,978
Ensembl chr 2:36,583,412...36,619,001

G

SLIT-ROBO Rho GTPase activating protein 1

increases methylation

EXP

Glyphosate results in increased methylation of SRGAP1 gene

NCBI chr 7:59,215,007...59,479,600
Ensembl chr 7:59,215,007...59,656,213

G

signal recognition particle 68

affects methylation

EXP

Glyphosate affects the methylation of SRP68 gene

NCBI chr10:101,980,089...102,006,913
Ensembl chr10:101,980,090...102,007,207

G

signal recognition particle 72

increases expression

ISO

Glyphosate results in increased expression of SRP72 protein

NCBI chr14:31,522,424...31,549,978
Ensembl chr14:31,522,963...31,550,151

G

SRSF protein kinase 3

increases expression

EXP

Glyphosate results in increased expression of SRPK3 mRNA

NCBI chr X:156,661,888...156,666,537
Ensembl chr X:156,661,875...156,666,531

G

serine/arginine repetitive matrix 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRRM2 mRNA

NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337

G

serine/arginine repetitive matrix 4

affects methylation

EXP

Glyphosate affects the methylation of SRRM4 gene

NCBI chr12:45,659,729...45,819,643
Ensembl chr12:45,660,450...45,816,475

G

serine and arginine rich splicing factor 1

increases expression

ISO

Glyphosate results in increased expression of SRSF1 protein

NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548

G

serine and arginine rich splicing factor 3

decreases expression

ISO

Glyphosate results in decreased expression of SRSF3 protein

NCBI chr20:7,093,529...7,103,517
Ensembl chr20:7,093,565...7,103,516

G

serine and arginine rich splicing factor 5

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRSF5 mRNA

NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:106,336,756...106,341,931

G

sulfiredoxin 1

decreases expression

ISO

Glyphosate results in decreased expression of SRXN1 mRNA

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

slingshot protein phosphatase 2

affects methylation

EXP

Glyphosate affects the methylation of SSH2 gene

NCBI chr10:62,555,388...62,807,457
Ensembl chr10:62,555,460...62,807,453

G

SCO-spondin

increases expression

EXP

Glyphosate results in increased expression of SSPO mRNA

NCBI chr 4:78,725,829...78,781,330
Ensembl chr 4:78,727,275...78,781,315

G

SSU72 homolog, RNA polymerase II CTD phosphatase

affects methylation

EXP

Glyphosate affects the methylation of SSU72 gene

NCBI chr 5:171,595,919...171,625,675
Ensembl chr 5:171,595,851...171,625,268

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

decreases methylation

EXP

Glyphosate results in decreased methylation of ST3GAL4 gene

NCBI chr 8:41,673,510...41,723,158
Ensembl chr 8:41,673,510...41,712,551

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 2

affects methylation

EXP

Glyphosate affects the methylation of ST6GAL2 gene

NCBI chr 9:9,508,928...9,606,900
Ensembl chr 9:9,509,548...9,594,007

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of ST6GALNAC5 gene
Glyphosate affects the methylation of ST6GALNAC5 gene

PMID:31011160 PMID:35440735

NCBI chr 2:244,398,604...244,571,100
Ensembl chr 2:244,402,589...244,571,097

G

steroidogenic acute regulatory protein

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of STAR mRNA; Glyphosate results in decreased expression of STAR protein
Glyphosate results in increased expression of STAR mRNA alternative form

PMID:10964798 PMID:33957581

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

StAR-related lipid transfer domain containing 9

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of STARD9 mRNA

NCBI chr 3:128,034,866...128,150,493
Ensembl chr 3:128,034,908...128,127,402

G

signal transducer and activator of transcription 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of STAT1 mRNA

NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346

G

signal transducer and activator of transcription 3

decreases expression

ISO

Glyphosate results in decreased expression of STAT3 mRNA

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

stanniocalcin 1

increases expression

ISO

Glyphosate results in increased expression of STC1 mRNA

NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082

G

stanniocalcin 2

decreases expression

EXP

Glyphosate results in decreased expression of STC2 mRNA

NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447

G

serine/threonine kinase 24

decreases methylation

EXP

Glyphosate results in decreased methylation of STK24 gene

NCBI chr15:104,770,556...104,866,524
Ensembl chr15:104,773,569...104,865,975

G

storkhead box 2

affects methylation

EXP

Glyphosate affects the methylation of STOX2 gene

NCBI chr16:51,580,855...51,819,909
Ensembl chr16:51,580,798...51,815,209

G

syntaxin 11

affects methylation
decreases expression

EXP
ISO

Glyphosate affects the methylation of STX11 gene
Glyphosate results in decreased expression of STX11 mRNA

PMID:33713393 PMID:35440735

NCBI chr 1:9,111,216...9,140,227
Ensembl chr 1:9,107,796...9,178,455

G

syntaxin 12

decreases methylation

EXP

Glyphosate results in decreased methylation of STX12 gene

NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:150,334,836...150,376,346

G

succinate-CoA ligase ADP-forming subunit beta

decreases expression

EXP

Glyphosate results in decreased expression of SUCLA2 mRNA

NCBI chr15:55,161,894...55,215,031
Ensembl chr15:55,161,868...55,215,029

G

succinate-CoA ligase GDP-forming subunit beta

decreases expression

EXP

Glyphosate results in decreased expression of SUCLG2 mRNA

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296

G

succinylCoA:glutarate-CoA transferase

affects methylation

EXP

Glyphosate affects the methylation of SUGCT gene

NCBI chr17:52,072,012...52,929,852
Ensembl chr17:52,072,052...52,930,281

G

sulfatase 1

decreases expression

ISO

Glyphosate results in decreased expression of SULF1 mRNA

NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643

G

sulfatase 2

increases methylation

EXP

Glyphosate results in increased methylation of SULF2 gene

NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651

G

sulfotransferase family 1E member 1

increases methylation

EXP

Glyphosate results in increased methylation of SULT1E1 gene

NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716

G

sulfotransferase family 6B member 1

increases expression

ISO

Glyphosate results in increased expression of SULT6B1 mRNA

NCBI chr 6:21,914,535...21,939,264
Ensembl chr 6:21,914,535...21,939,264

G

small ubiquitin-like modifier 2

decreases expression

ISO

Glyphosate results in decreased expression of SUMO2 mRNA

NCBI chr10:101,270,899...101,283,458
Ensembl chr10:101,270,900...101,283,938
Ensembl chr 5:101,270,900...101,283,938

G

Suv3 like RNA helicase

increases methylation

EXP

Glyphosate results in increased methylation of SUPV3L1 gene

NCBI chr20:30,921,248...30,941,779
Ensembl chr20:30,921,249...30,941,723

G

sushi domain containing 2

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA
Glyphosate results in increased expression of SUSD2 mRNA

PMID:33854195 PMID:35897073

NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,016,907...13,024,264

G

synaptic vesicle glycoprotein 2a

decreases methylation

EXP

Glyphosate results in decreased methylation of SV2A gene

NCBI chr 2:186,430,363...186,446,161
Ensembl chr 2:186,430,345...186,448,065

G

SV2 related protein

increases methylation

EXP

Glyphosate results in increased methylation of SVOP gene

NCBI chr12:48,191,549...48,251,185
Ensembl chr12:48,191,573...48,251,464

G

synaptonemal complex central element protein 1

increases methylation

EXP

Glyphosate results in increased methylation of SYCE1 gene

NCBI chr 1:205,281,808...205,292,811
Ensembl chr 1:205,218,653...205,322,623

G

synaptonemal complex protein 2

increases expression

ISO

Glyphosate results in increased expression of SYCP2 mRNA

NCBI chr 3:185,814,033...185,876,516
Ensembl chr 3:185,814,035...185,876,492

G

spleen associated tyrosine kinase

decreases expression

ISO

Glyphosate results in decreased expression of SYK mRNA

NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278

G

symplekin scaffold protein

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SYMPK mRNA

NCBI chr 1:87,800,416...87,828,727
Ensembl chr 1:87,799,853...87,828,727

G

synapse differentiation inducing 1-like

decreases methylation

EXP

Glyphosate results in decreased methylation of SYNDIG1L gene

NCBI chr 6:110,053,713...110,076,058
Ensembl chr 6:110,054,504...110,075,969

G

spectrin repeat containing, nuclear envelope family member 3

increases expression

ISO

Glyphosate results in increased expression of SYNE3 mRNA

NCBI chr 6:129,637,644...129,729,542
Ensembl chr 6:129,641,123...129,729,509

G

synaptic Ras GTPase activating protein 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of SYNGAP1 mRNA
Glyphosate results in increased expression of SYNGAP1 mRNA

NCBI chr20:5,028,226...5,058,519
Ensembl chr20:5,026,707...5,057,751

G

synaptopodin 2

affects methylation

ISO
EXP

Glyphosate affects the methylation of SYNPO2 gene

PMID:35377194 PMID:35440735

NCBI chr 2:213,901,685...214,055,844
Ensembl chr 2:213,900,868...214,055,844

G

synaptotagmin 17

decreases expression

EXP

Glyphosate results in decreased expression of SYT17 mRNA

NCBI chr 1:182,129,491...182,195,827
Ensembl chr 1:182,129,496...182,204,028

G

synaptotagmin-like 5

affects methylation

EXP

Glyphosate affects the methylation of SYTL5 gene

NCBI chr X:15,461,215...15,702,660
Ensembl chr X:15,460,472...15,550,471

G

SZT2 subunit of KICSTOR complex

affects methylation

EXP

Glyphosate affects the methylation of SZT2 gene

NCBI chr 5:137,182,648...137,229,349
Ensembl chr 5:137,182,648...137,229,419

G

brachyury 2

decreases expression

EXP

Glyphosate results in decreased expression of T2 mRNA

NCBI chr 1:54,866,023...54,932,332
Ensembl chr 1:54,866,023...54,932,332

G

tachykinin, precursor 1

increases expression

ISO

Glyphosate results in increased expression of TAC1 mRNA

NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546

G

transforming, acidic coiled-coil containing protein 2

increases methylation

EXP

Glyphosate results in increased methylation of TACC2 gene

NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152

G

TATA-box binding protein associated factor, RNA polymerase I subunit D

increases expression

EXP

Glyphosate results in increased expression of TAF1D mRNA

NCBI chr 8:20,427,894...20,438,046
Ensembl chr 8:20,427,954...20,434,556

G

TAFA chemokine like family member 1

affects methylation
decreases expression

EXP

Glyphosate affects the methylation of TAFA1 gene
Glyphosate results in decreased expression of TAFA1 mRNA

PMID:35440735 PMID:38314887

NCBI chr 4:130,294,659...130,799,139
Ensembl chr 4:130,294,991...130,800,900

G

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

affects methylation

EXP

Glyphosate affects the methylation of TANC1 gene

NCBI chr 3:64,508,037...64,741,826
Ensembl chr 3:64,508,085...64,741,825

G

TAO kinase 2

decreases expression

ISO

Glyphosate results in decreased expression of TAOK2 mRNA

NCBI chr 1:190,906,236...190,925,359
Ensembl chr 1:190,906,239...190,925,140

G

transporter 1, ATP binding cassette subfamily B member

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of TAP1 mRNA

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810

G

threonyl-tRNA synthetase 1

decreases expression

ISO

Glyphosate results in decreased expression of TARS protein

NCBI chr 2:62,095,978...62,114,802
Ensembl chr 2:62,087,763...62,114,802

G

taste receptor, type 2, member 137

decreases expression

EXP

Glyphosate results in decreased expression of TAS2R137 mRNA

NCBI chr 4:70,242,964...70,256,215
Ensembl chr 4:70,251,091...70,252,041

G

tyrosine aminotransferase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TAT mRNA

NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482

G

Tax1 binding protein 1

affects methylation

EXP

Glyphosate affects the methylation of TAX1BP1 gene

NCBI chr 4:83,152,549...83,208,463
Ensembl chr 4:83,110,062...83,209,657

G

TBC1 domain family, member 14

increases expression

ISO

Glyphosate results in increased expression of TBC1D14 mRNA

NCBI chr14:78,397,345...78,496,863
Ensembl chr14:78,397,355...78,496,865

G

TBC1 domain family, member 22a

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of TBC1D22A gene
Glyphosate affects the methylation of TBC1D22A gene

PMID:31011160 PMID:35440735

NCBI chr 7:119,172,284...119,457,271
Ensembl chr 7:119,172,333...119,457,271

G

TBC1 domain family, member 5

decreases methylation

EXP

Glyphosate results in decreased methylation of TBC1D5 gene

NCBI chr 9:3,740,032...4,256,971
Ensembl chr 9:3,750,325...4,253,581

G

TANK-binding kinase 1

decreases expression

ISO

Glyphosate results in decreased expression of TBK1 mRNA

NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357

G

TBL1X/Y related 1

decreases expression

ISO

Glyphosate results in decreased expression of TBL1XR1 mRNA

NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:106,730,665...106,857,989

G

T-box transcription factor 4

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of TBX4 mRNA

NCBI chr10:71,228,145...71,258,222
Ensembl chr10:71,197,727...71,258,218

G

thromboxane A synthase 1

decreases expression

EXP

Glyphosate results in decreased expression of TBXAS1 mRNA

NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969

G

T-box transcription factor T

decreases expression

EXP

Glyphosate results in decreased expression of TBXT mRNA

NCBI chr 1:54,845,674...54,859,340
Ensembl chr 1:54,845,674...54,853,583

G

tandem C2 domains, nuclear

affects methylation

EXP

Glyphosate affects the methylation of TC2N gene

NCBI chr 6:126,526,006...126,622,163
Ensembl chr 6:126,526,009...126,614,215

G

transcription elongation factor A like 7

decreases expression

EXP

Glyphosate results in decreased expression of TCEAL7 mRNA

NCBI chr X:104,020,016...104,022,176
Ensembl chr X:104,011,409...104,022,176

G

transcription factor 21

decreases expression

EXP

Glyphosate results in decreased expression of TCF21 mRNA

NCBI chr 1:24,520,499...24,523,358
Ensembl chr 1:24,520,481...24,523,348

G

transcription factor 23

affects methylation

EXP

Glyphosate affects the methylation of TCF23 gene

NCBI chr 6:31,117,839...31,126,575
Ensembl chr 6:31,120,127...31,125,878

G

transcription factor 4

increases methylation

EXP

Glyphosate results in increased methylation of TCF4 gene

NCBI chr18:65,216,840...65,563,186
Ensembl chr18:65,216,849...65,558,401

G

t-complex protein 1, pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of TCP1-PS1 gene

NCBI chr 4:122,262,936...122,264,512

G

t-complex 11 like 1

increases expression

ISO

Glyphosate results in increased expression of TCP11L1 mRNA

NCBI chr 3:111,478,787...111,547,553
Ensembl chr 3:111,453,221...111,546,454

G

tryptophan 2,3-dioxygenase

increases expression
decreases expression

ISO

Glyphosate results in increased expression of TDO2 protein
Glyphosate results in decreased expression of TDO2 mRNA

PMID:33713393 PMID:37208198

NCBI chr 2:169,567,656...169,585,586
Ensembl chr 2:169,567,654...169,585,586

G

tyrosyl-DNA phosphodiesterase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TDP2 mRNA

NCBI chr17:40,656,969...40,668,362
Ensembl chr17:40,656,971...40,668,288

G

TD and POZ domain containing 2 like 2

increases methylation

EXP

Glyphosate results in increased methylation of TDPOZ2L2 gene

NCBI chr 2:182,597,137...182,598,231

G

TEA domain transcription factor 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TEAD2 mRNA

NCBI chr 1:104,838,795...104,855,635
Ensembl chr 1:104,838,623...104,855,630

G

tectonin beta-propeller repeat containing 1

affects methylation

EXP

Glyphosate affects the methylation of TECPR1 gene

NCBI chr12:15,504,456...15,534,541
Ensembl chr12:15,505,343...15,534,116

G

trans-2,3-enoyl-CoA reductase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TECR mRNA

NCBI chr19:41,431,422...41,472,880
Ensembl chr19:41,446,071...41,474,432

G

tektin 3

decreases expression

EXP

Glyphosate results in decreased expression of TEKT3 mRNA

NCBI chr10:48,228,859...48,262,812
Ensembl chr10:48,228,804...48,262,811

G

tektin 5 like 1

increases expression

EXP

Glyphosate results in increased expression of TEKT5L1 mRNA

NCBI chr 1:236,103,061...236,118,680

G

TEN1 subunit of CST complex

decreases expression

EXP

Glyphosate results in decreased expression of TEN1 mRNA

NCBI chr10:101,930,212...101,951,932
Ensembl chr10:101,930,222...101,953,979

G

teneurin transmembrane protein 3

affects methylation

EXP

Glyphosate affects the methylation of TENM3 gene

NCBI chr16:47,984,732...50,711,352
Ensembl chr16:49,829,750...50,711,352

G

teneurin transmembrane protein 4

decreases methylation

EXP

Glyphosate results in decreased methylation of TENM4 gene

NCBI chr 1:157,699,611...160,674,549
Ensembl chr 1:159,974,017...160,674,549

G

terminal nucleotidyltransferase 5A

increases expression
decreases expression

ISO

Glyphosate results in increased expression of TENT5A mRNA
Glyphosate results in decreased expression of FAM46A mRNA

PMID:33713393 PMID:35897073

NCBI chr 8:95,102,349...95,109,100
Ensembl chr 8:95,105,412...95,109,100

G

tet methylcytosine dioxygenase 3

increases expression

EXP

Glyphosate results in increased expression of TET3 mRNA

NCBI chr 4:117,425,106...117,525,495
Ensembl chr 4:117,429,857...117,520,486

G

testis expressed 11

decreases expression

ISO

Glyphosate results in decreased expression of TEX11 mRNA

NCBI chr X:69,973,012...70,236,544
Ensembl chr X:69,972,723...70,236,011

G

testis expressed 15, meiosis and synapsis associated

affects methylation

EXP

Glyphosate affects the methylation of TEX15 gene

NCBI chr16:65,302,049...65,362,065
Ensembl chr16:65,302,049...65,361,462

G

transferrin

decreases expression

ISO

Glyphosate results in decreased expression of TF protein

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transcription factor AP-2 alpha

decreases expression

ISO

Glyphosate results in decreased expression of TFAP2A mRNA

NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219

G

transcription factor Dp-1

decreases expression

ISO

Glyphosate results in decreased expression of TFDP1 mRNA

NCBI chr16:82,864,220...82,903,166
Ensembl chr16:82,864,226...82,902,996

G

trefoil factor 2

increases expression

ISO

Glyphosate results in increased expression of TFF2 mRNA

NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,217,121...9,220,979

G

thyroglobulin

increases expression
multiple interactions
decreases expression

EXP
ISO

Glyphosate results in increased expression of TG mRNA
Melatonin inhibits the reaction [Glyphosate results in decreased expression of TG mRNA]
Glyphosate results in decreased expression of TG protein

PMID:32145347 PMID:33159990 PMID:36462676

NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:100,307,349...100,314,539
Ensembl chr 7:100,307,349...100,314,539

G

TDP-glucose 4,6-dehydratase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TGDS mRNA

NCBI chr15:101,581,765...101,602,779
Ensembl chr15:101,582,227...101,602,718

G

transforming growth factor, beta 1

decreases expression
increases expression

ISO
EXP

Glyphosate results in decreased expression of TGFB1 mRNA
Glyphosate results in increased expression of TGFB1 protein
Glyphosate results in increased expression of TGFB1 mRNA

PMID:28711546 PMID:34953950 PMID:37047296

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor, beta induced

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TGFBI mRNA

NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471

G

transforming growth factor, beta receptor 1

decreases expression

ISO

Glyphosate results in decreased expression of TGFBR1 mRNA

NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260

G

transforming growth factor, beta receptor 2

decreases expression

ISO

Glyphosate results in decreased expression of TGFBR2 mRNA

NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469

G

TGFB-induced factor homeobox 1

increases expression

ISO

Glyphosate results in increased expression of TGIF1 mRNA

NCBI chr 9:118,194,735...118,204,354
Ensembl chr 9:118,194,444...118,204,442

G

TGFB-induced factor homeobox 2

increases expression

ISO

Glyphosate results in increased expression of TGIF2 mRNA

NCBI chr 3:165,791,101...165,808,669
Ensembl chr 3:165,793,480...165,808,666

G

transglutaminase 2

increases expression

ISO

Glyphosate results in increased expression of TGM2 protein

NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240

G

transglutaminase 5

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of TGM5 mRNA

NCBI chr 3:128,461,836...128,497,761
Ensembl chr 3:128,461,836...128,497,761

G

THAP domain containing 12

increases methylation

EXP

Glyphosate results in increased methylation of THAP12 gene

NCBI chr 1:162,414,781...162,430,560
Ensembl chr 1:162,414,723...162,430,551

G

thrombospondin 1

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of THBS1 mRNA
Glyphosate results in increased expression of THBS1 mRNA

PMID:31295307 PMID:35489704

NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402

G

thrombospondin 3

decreases expression

ISO

Glyphosate results in decreased expression of THBS3 mRNA

NCBI chr 2:176,919,549...176,931,357
Ensembl chr 2:176,919,230...176,931,357

G

thioesterase superfamily member 4

decreases expression

ISO

Glyphosate results in decreased expression of THEM4 mRNA

NCBI chr 2:184,642,603...184,663,752
Ensembl chr 2:184,642,595...184,665,344

G

thymocyte selection associated family member 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of THEMIS2 mRNA

NCBI chr 5:150,275,094...150,290,343
Ensembl chr 5:150,275,094...150,290,343

G

thyroid hormone receptor alpha

increases expression

EXP

Glyphosate results in increased expression of THRA mRNA

PMID:27916585 PMID:33512083

NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657

G

thyroid hormone receptor beta

decreases expression
increases expression

EXP

Glyphosate results in decreased expression of THRB mRNA
Glyphosate results in increased expression of THRB mRNA

PMID:27916585 PMID:33512083

NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680

G

TIAM Rac1 associated GEF 1

decreases expression
increases methylation

ISO
EXP

Glyphosate results in decreased expression of TIAM1 mRNA
Glyphosate results in increased methylation of TIAM1 gene

PMID:31011160 PMID:31295307

NCBI chr11:42,517,527...42,866,280
Ensembl chr11:42,517,528...42,646,075

G

T cell immunoreceptor with Ig and ITIM domains

increases methylation

EXP

Glyphosate results in increased methylation of TIGIT gene

NCBI chr11:70,534,907...70,552,452
Ensembl chr11:70,534,848...70,552,467

G

TIMP metallopeptidase inhibitor 3

increases expression

ISO

Glyphosate results in increased expression of TIMP3 mRNA

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

tight junction associated protein 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA

NCBI chr 9:22,198,984...22,223,201
Ensembl chr 9:22,199,676...22,223,201

G

tight junction protein 1

multiple interactions
decreases expression

EXP

Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of TJP1 protein]; NOX1 protein affects the reaction [Glyphosate results in decreased expression of TJP1 protein]
Glyphosate results in decreased expression of TJP1 mRNA; Glyphosate results in decreased expression of TJP1 protein

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

transketolase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TKT mRNA

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431

G

tolloid-like 2

affects methylation
decreases methylation

EXP

Glyphosate affects the methylation of TLL2 gene
Glyphosate results in decreased methylation of TLL2 gene

PMID:31011160 PMID:35440735

NCBI chr 1:249,862,050...249,977,566
Ensembl chr 1:249,862,050...249,977,566

G

toll-like receptor 9

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of TLR9 mRNA

NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148

G

transmembrane 4 L six family member 5

affects methylation

EXP

Glyphosate affects the methylation of TM4SF5 gene

NCBI chr10:55,718,014...55,724,372
Ensembl chr10:55,717,552...55,724,372

G

translation machinery associated 16 homolog

increases expression

ISO

Glyphosate results in increased expression of TMA16 mRNA

NCBI chr16:28,003,002...28,021,875
Ensembl chr16:27,980,900...28,021,875

G

transmembrane BAX inhibitor motif containing 6

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMBIM6 mRNA

NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492

G

transmembrane and coiled-coil domain family 3

increases expression

ISO

Glyphosate results in increased expression of TMCC3 mRNA

NCBI chr 7:30,781,452...31,058,888
Ensembl chr 7:30,897,991...31,058,889

G

transmembrane p24 trafficking protein 2

decreases methylation

EXP

Glyphosate results in decreased methylation of TMED2 gene

NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606

G

transmembrane protein 117

decreases methylation

EXP

Glyphosate results in decreased methylation of TMEM117 gene

NCBI chr 7:127,636,862...128,098,944
Ensembl chr 7:127,636,825...128,098,941

G

transmembrane protein 158

increases methylation

EXP

Glyphosate results in increased methylation of TMEM158 gene

NCBI chr 8:131,791,137...131,792,135
Ensembl chr 8:131,787,277...131,796,882

G

transmembrane protein 182

increases expression

ISO

Glyphosate results in increased expression of TMEM182 mRNA

NCBI chr 9:50,555,029...50,606,908
Ensembl chr 9:50,550,462...50,606,907

G

transmembrane protein 215

decreases expression

EXP

Glyphosate results in decreased expression of TMEM215 mRNA

NCBI chr 5:60,408,587...60,411,841
Ensembl chr 5:60,406,763...60,413,601

G

transmembrane protein 232

increases methylation

EXP

Glyphosate results in increased methylation of TMEM232 gene

NCBI chr 9:112,334,569...112,562,627
Ensembl chr 9:112,334,569...112,580,069

G

transmembrane protein 268

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TMEM268 mRNA

NCBI chr 5:81,990,314...82,016,970
Ensembl chr 5:81,991,367...82,016,968

G

transmembrane protein 30C

increases methylation

EXP

Glyphosate results in increased methylation of TMEM30C gene

NCBI chr11:56,708,788...56,727,633
Ensembl chr11:56,710,635...56,727,631

G

transmembrane protein 68

decreases expression

ISO

Glyphosate results in decreased expression of TMEM68 mRNA

NCBI chr 5:21,291,675...21,322,443
Ensembl chr 5:21,291,675...21,322,443

G

trimethyllysine hydroxylase, epsilon

affects methylation

EXP

Glyphosate affects the methylation of TMLHE gene

NCBI chr20:96,561...144,414
Ensembl chr20:107,516...144,543

G

transmembrane serine protease 5

affects methylation

EXP

Glyphosate affects the methylation of TMPRSS5 gene

NCBI chr 8:58,338,455...58,357,886
Ensembl chr 8:58,338,397...58,357,881

G

thiol methyltransferase 1B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMT1B mRNA

NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980

G

tumor necrosis factor

multiple interactions
increases expression

ISO
EXP

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNF mRNA
Glyphosate results in increased expression of TNF mRNA
Glyphosate results in increased expression of and results in increased secretion of TNF protein
Glyphosate results in increased expression of TNF mRNA; Glyphosate results in increased expression of TNF protein

PMID:21784030 PMID:31874349 PMID:32045792 PMID:32067069 PMID:32800223 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF alpha induced protein 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TNFAIP2 mRNA

NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:136,298,082...136,311,106

G

TNF receptor superfamily member 10b

multiple interactions

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TNFRSF10A mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNFRSF10A mRNA

NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082

G

TNF receptor superfamily member 11B

increases expression

ISO

Glyphosate results in increased expression of TNFRSF11B mRNA

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF receptor superfamily member 1A

decreases expression

ISO

Glyphosate results in decreased expression of TNFRSF1A mRNA

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF receptor superfamily member 1B

increases methylation

EXP

Glyphosate results in increased methylation of TNFRSF1B gene

NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411

G

tumor necrosis factor receptor superfamily, member 22

increases expression

ISO

Glyphosate results in increased expression of TNFRSF10C mRNA

NCBI chr 1:208,269,844...208,285,823
Ensembl chr 1:208,258,836...208,289,832

G

TNF superfamily member 10

decreases expression

ISO

Glyphosate results in decreased expression of TNFSF10 mRNA

PMID:31295307 PMID:35897073

NCBI chr 2:112,136,550...112,155,903

G

troponin T1, slow skeletal type

decreases expression

EXP

Glyphosate results in decreased expression of TNNT1 mRNA

NCBI chr 1:78,349,035...78,359,394
Ensembl chr 1:78,349,035...78,359,394

G

tenascin R

increases expression

ISO

Glyphosate results in increased expression of TNR mRNA

NCBI chr13:74,285,141...74,706,174
Ensembl chr13:74,507,366...74,701,115

G

tensin 1

increases expression
increases methylation

ISO
EXP

Glyphosate results in increased expression of TNS1 mRNA
Glyphosate results in increased methylation of TNS1 gene

PMID:31011160 PMID:35897073

NCBI chr 9:82,941,068...83,152,007
Ensembl chr 9:82,941,068...83,152,007

G

tensin 3

decreases expression
increases expression

ISO

Glyphosate results in decreased expression of TNS3 protein
Glyphosate results in increased expression of TNS3 mRNA

PMID:35897073 PMID:36173347

NCBI chr14:87,387,441...87,619,457
Ensembl chr14:87,387,441...87,619,712

G

tenascin XB

decreases expression

ISO

Glyphosate results in decreased expression of TNXB mRNA

PMID:28711546 PMID:31295307

Ensembl chr20:4,031,082...4,090,128

G

DNA topoisomerase II alpha

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of TOP2A mRNA

NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366

G

torsin family 3, member A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TOR3A mRNA

NCBI chr13:71,324,073...71,348,625
Ensembl chr13:71,324,076...71,348,624

G

TOX high mobility group box family member 2

decreases expression

EXP

Glyphosate results in decreased expression of TOX2 mRNA

NCBI chr 3:172,272,718...172,400,235
Ensembl chr 3:172,272,736...172,400,233

G

TOX high mobility group box family member 3

increases methylation

EXP

Glyphosate results in increased methylation of TOX3 gene

NCBI chr19:32,820,957...32,929,776
Ensembl chr19:32,820,977...32,929,776

G

tumor protein p53

increases expression
decreases expression
multiple interactions
increases activity
increases methylation

ISO

Glyphosate results in increased expression of TP53 mRNA
Glyphosate results in decreased expression of TP53 mRNA
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TP53 mRNA
Glyphosate results in increased activity of TRP53 protein
Glyphosate results in increased methylation of TP53 promoter

PMID:22634143 PMID:31751608 PMID:31874349 PMID:32800223

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p53 binding protein 1

increases expression

ISO

Glyphosate results in increased expression of TRP53BP1 mRNA

NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747

G

tumor protein p53 inducible protein 3

affects methylation

EXP

Glyphosate affects the methylation of TP53I3 gene

NCBI chr 6:33,537,779...33,545,204

G

tumor protein p63

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of TRP63 mRNA

NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177

G

tumor protein p73

decreases expression

EXP

Glyphosate results in decreased expression of TP73 mRNA

NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552

G

thiopurine S-methyltransferase

decreases expression

ISO

Glyphosate results in decreased expression of TPMT protein

NCBI chr17:17,850,308...17,868,976
Ensembl chr17:17,850,279...17,868,976

G

thyroid peroxidase

increases expression
decreases expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of TPO mRNA
Glyphosate results in decreased expression of TPO mRNA
Melatonin inhibits the reaction [Glyphosate results in decreased expression of TPO mRNA]

PMID:33159990 PMID:36462676

NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793

G

tripeptidyl peptidase 2

decreases expression

ISO

Glyphosate results in decreased expression of TPP2 protein

NCBI chr 9:53,538,788...53,620,253
Ensembl chr 9:53,538,313...53,620,251

G

tumor protein, translationally-controlled 1

decreases expression

ISO

Glyphosate results in decreased expression of TPT1 protein

NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554

G

Tnf receptor-associated factor 3

increases expression

ISO

Glyphosate results in increased expression of TRAF3 mRNA

NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:136,027,157...136,128,363

G

Traf3 interacting protein 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAF3IP2 mRNA

NCBI chr20:44,565,992...44,609,240
Ensembl chr20:44,517,242...44,609,618

G

Tnf receptor associated factor 4

increases expression

ISO

Glyphosate results in increased expression of TRAF4 mRNA

NCBI chr10:63,552,251...63,558,356
Ensembl chr10:63,552,253...63,558,356

G

TNF receptor-associated factor 5

increases expression

EXP

Glyphosate results in increased expression of TRAF5 mRNA

NCBI chr13:106,100,921...106,149,724
Ensembl chr13:106,103,291...106,149,707

G

TNF receptor associated factor 6

decreases expression

ISO

Glyphosate results in decreased expression of TRAF6 mRNA

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328

G

TRAF type zinc finger domain containing 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA

NCBI chr12:40,826,251...40,840,169
Ensembl chr12:40,825,851...40,841,320

G

trafficking protein particle complex subunit 11

affects methylation

EXP

Glyphosate affects the methylation of TRAPPC11 gene

NCBI chr16:51,465,631...51,512,003
Ensembl chr16:51,465,524...51,512,004

G

trafficking protein particle complex subunit 12

increases expression

ISO

Glyphosate results in increased expression of TRAPPC12 mRNA

NCBI chr 6:51,049,878...51,115,343
Ensembl chr 6:51,049,878...51,115,297

G

trafficking protein particle complex subunit 6A

decreases methylation

EXP

Glyphosate results in decreased methylation of TRAPPC6A gene

NCBI chr 1:88,286,533...88,293,493
Ensembl chr 1:88,286,362...88,293,493

G

thyrotropin releasing hormone

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of TRH mRNA; Glyphosate results in increased expression of TRH protein
Melatonin inhibits the reaction [Glyphosate results in increased expression of TRH protein]

PMID:33159990 PMID:35897073

NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762

G

thyrotropin releasing hormone receptor

multiple interactions
increases expression

ISO

Melatonin inhibits the reaction [Glyphosate results in increased expression of TRHR mRNA]

NCBI chr 7:77,233,175...77,277,988
Ensembl chr 7:77,233,354...77,277,987

G

tripartite motif-containing 17

decreases expression

ISO

Glyphosate results in decreased expression of TRIM17 mRNA

NCBI chr10:44,242,688...44,250,504
Ensembl chr10:44,240,184...44,250,494

G

tripartite motif-containing 31

multiple interactions

ISO

[Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which affects the methylation of TRIM31 promoter

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,658,386...1,671,711

G

tripartite motif-containing 34

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRIM34 mRNA

NCBI chr 1:168,119,043...168,130,544
Ensembl chr 1:168,119,074...168,132,059

G

tripartite motif-containing 50

increases expression

EXP

Glyphosate results in increased expression of TRIM50 mRNA

NCBI chr12:26,937,349...26,954,286
Ensembl chr12:26,937,349...26,954,270

G

thyroid hormone receptor interactor 6

decreases methylation

EXP

Glyphosate results in decreased methylation of TRIP6 gene

NCBI chr12:25,022,959...25,027,366
Ensembl chr12:25,022,909...25,027,363

G

trophinin

increases expression

ISO

Glyphosate results in increased expression of TRO mRNA

NCBI chr X:22,990,922...23,001,955
Ensembl chr X:22,990,922...23,001,944

G

transient receptor potential cation channel, subfamily M, member 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of TRPM2 mRNA

NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,704,482...10,752,802

G

transient receptor potential cation channel, subfamily M, member 3

decreases methylation

EXP

Glyphosate results in decreased methylation of TRPM3 gene

NCBI chr 1:229,099,741...229,984,172
Ensembl chr 1:229,099,542...229,984,172

G

transient receptor potential cation channel, subfamily M, member 6

decreases expression

EXP

Glyphosate results in decreased expression of TRPM6 mRNA

NCBI chr 1:225,559,528...225,747,106
Ensembl chr 1:225,576,872...225,747,108

G

transient receptor potential cation channel, subfamily V, member 5

decreases expression

EXP

Glyphosate results in decreased expression of TRPV5 mRNA

NCBI chr 4:71,503,085...71,531,134
Ensembl chr 4:71,503,093...71,529,384

G

TSC complex subunit 1

increases expression

ISO

Glyphosate results in increased expression of TSC1 mRNA

NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:32,367,670...32,416,568

G

TSC22 domain family, member 3

multiple interactions
increases expression

EXP
ISO

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TSC22D3 mRNA
Glyphosate results in increased expression of TSC22D3 mRNA

PMID:33854195 PMID:35897073

NCBI chr X:109,006,410...109,066,389
Ensembl chr X:109,006,420...109,015,519

G

thyroid stimulating hormone subunit beta

increases secretion
decreases expression
multiple interactions

EXP
ISO

Glyphosate results in increased secretion of TSHB protein
Glyphosate results in decreased expression of TSHB protein
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of TSHB mRNA; Melatonin inhibits the reaction [Glyphosate results in decreased expression of TSHB protein]

PMID:27916585 PMID:32145347 PMID:33159990 PMID:37567420

NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984

G

thyroid stimulating hormone receptor

increases expression
decreases expression
multiple interactions

EXP
ISO

Glyphosate results in increased expression of TSHR mRNA
Glyphosate results in decreased expression of TSHR mRNA
Melatonin inhibits the reaction [Glyphosate results in decreased expression of TSHR mRNA]

PMID:33159990 PMID:36462676

NCBI chr 6:116,072,321...116,206,009
Ensembl chr 6:116,072,281...116,206,010

G

thymic stromal lymphopoietin

multiple interactions
increases expression

ISO

IL13 protein affects the reaction [Glyphosate results in increased expression of TSLP protein]

NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420

G

tetraspanin 14

affects methylation

EXP

Glyphosate affects the methylation of TSPAN14 gene

NCBI chr16:16,818,344...16,875,462
Ensembl chr16:16,818,344...16,875,674

G

tetraspanin 31

decreases expression

EXP

Glyphosate results in decreased expression of TSPAN31 mRNA

NCBI chr 7:64,774,881...64,783,534
Ensembl chr 7:64,774,910...64,777,726

G

tetraspanin 5

affects methylation

EXP

Glyphosate affects the methylation of TSPAN5 gene

NCBI chr 2:229,967,521...230,139,012
Ensembl chr 2:229,967,235...230,142,685

G

testis-specific serine kinase 1B

decreases expression

EXP

Glyphosate results in decreased expression of TSSK1B mRNA

NCBI chr11:96,595,216...96,596,639
Ensembl chr11:96,576,866...96,598,715

G

tau tubulin kinase 1

increases methylation

EXP

Glyphosate results in increased methylation of TTBK1 gene

NCBI chr 9:21,990,973...22,035,961
Ensembl chr 9:21,990,973...22,035,961

G

tau tubulin kinase 2

increases expression
affects methylation

ISO
EXP

Glyphosate results in increased expression of TTBK2 mRNA
Glyphosate affects the methylation of TTBK2 gene

PMID:35440735 PMID:35897073

NCBI chr 3:128,144,851...128,256,630
Ensembl chr 3:128,144,851...128,258,738

G

tetratricopeptide repeat domain 17

increases methylation

EXP

Glyphosate results in increased methylation of TTC17 gene

NCBI chr 3:100,718,820...100,829,464
Ensembl chr 3:100,718,827...100,829,129

G

tetratricopeptide repeat domain 21A

decreases expression

EXP

Glyphosate results in decreased expression of TTC21A mRNA

NCBI chr 8:128,544,684...128,580,464
Ensembl chr 8:128,544,734...128,580,086

G

tetratricopeptide repeat domain 22

decreases expression

EXP

Glyphosate results in decreased expression of TTC22 mRNA

NCBI chr 5:126,630,808...126,651,954
Ensembl chr 5:126,634,864...126,651,949

G

tetratricopeptide repeat domain 28

increases methylation

EXP

Glyphosate results in increased methylation of TTC28 gene

NCBI chr12:51,002,816...51,443,461
Ensembl chr12:51,005,089...51,443,531

G

tetratricopeptide repeat domain 6

affects methylation

EXP

Glyphosate affects the methylation of TTC6 gene

NCBI chr 6:80,872,055...81,103,170
Ensembl chr 6:80,889,487...81,103,163

G

tubulin tyrosine ligase like 12

decreases expression

ISO

Glyphosate results in decreased expression of TTLL12 protein

NCBI chr 7:116,612,609...116,631,244
Ensembl chr 7:116,612,609...116,631,577

G

titin

affects methylation

EXP

Glyphosate affects the methylation of TTN gene

NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171

G

transthyretin

decreases expression

EXP

Glyphosate results in decreased expression of TTR mRNA

NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969

G

tubulin, alpha 1A

decreases expression

ISO

Glyphosate results in decreased expression of TUBA1A mRNA

NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035

G

tubulin, alpha 1B

decreases expression

ISO

Glyphosate results in decreased expression of TUBA1B mRNA

NCBI chr 7:131,969,606...131,972,587
Ensembl chr 7:131,968,770...131,996,035

G

tubulin, alpha 1C

decreases expression

ISO

Glyphosate results in decreased expression of TUBA1C mRNA

NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311

G

tubulin, beta 3 class III

increases expression
decreases expression

ISO

Glyphosate results in increased expression of TUBB3 mRNA; Glyphosate results in increased expression of TUBB3 protein
Glyphosate results in decreased expression of TUBB3 mRNA

PMID:31874349 PMID:33348142 PMID:35485992

NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740

G

tubulin, beta 4A class IVa

increases expression

ISO

Glyphosate results in increased expression of TUBB4A protein

NCBI chr 9:2,004,836...2,012,281
Ensembl chr 9:2,004,840...2,012,286

G

tubulin gamma complex component 4

affects methylation

EXP

Glyphosate affects the methylation of TUBGCP4 gene

NCBI chr 3:128,594,052...128,628,789
Ensembl chr 3:128,595,380...128,625,953

G

Tu translation elongation factor, mitochondrial

increases expression

ISO

Glyphosate results in increased expression of TUFM protein

NCBI chr 1:190,504,373...190,507,980
Ensembl chr 1:190,504,373...190,508,952

G

tumor suppressor candidate 3

affects methylation

EXP

Glyphosate affects the methylation of TUSC3 gene

NCBI chr16:59,899,642...60,048,813
Ensembl chr16:59,899,091...60,048,215

G

trans-golgi network vesicle protein 23 homolog A

increases methylation

EXP

Glyphosate results in increased methylation of TVP23A gene

NCBI chr10:5,734,100...5,770,002
Ensembl chr10:5,734,100...5,769,998

G

thioredoxin-like 1

decreases expression

ISO

Glyphosate results in decreased expression of TXNL1 protein

NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518

G

thioredoxin-like 4B

decreases expression

ISO

Glyphosate results in decreased expression of TXNL4B mRNA

NCBI chr19:54,439,686...54,449,777
Ensembl chr19:54,439,680...54,448,052

G

thymidine phosphorylase

increases methylation

EXP

Glyphosate results in increased methylation of TYMP gene

NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003

G

tRNA-yW synthesizing protein 1 homolog

increases methylation

EXP

Glyphosate results in increased methylation of TYW1 gene

NCBI chr12:31,968,198...32,054,454
Ensembl chr12:31,968,198...32,054,647

G

tRNA-yW synthesizing protein 3 homolog

increases methylation

EXP

Glyphosate results in increased methylation of TYW3 gene

NCBI chr 2:246,189,627...246,211,737
Ensembl chr 2:246,189,632...246,220,025

G

U2 small nuclear RNA auxiliary factor 2

increases methylation

EXP

Glyphosate results in increased methylation of U2AF2 gene

NCBI chr 1:77,789,752...77,807,307
Ensembl chr 1:77,789,752...77,807,413

G

ubiquitin-like modifier activating enzyme 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UBA3 mRNA

NCBI chr 4:131,346,219...131,367,378
Ensembl chr 4:131,346,224...131,367,277

G

ubiquitin-associated protein 1

affects methylation

EXP

Glyphosate affects the methylation of UBAP1 gene

NCBI chr 5:61,316,650...61,357,077
Ensembl chr 5:61,316,643...61,357,076

G

ubiquitin B

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBB mRNA

NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335

G

ubiquitin C

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBC mRNA

NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275

G

ubiquitin-conjugating enzyme E2C

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of UBE2C mRNA

NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678

G

ubiquitin-conjugating enzyme E2E 2

affects methylation

EXP

Glyphosate affects the methylation of UBE2E2 gene

NCBI chr15:9,411,067...9,688,731
Ensembl chr15:9,411,539...9,712,661

G

ubiquitin-conjugating enzyme E2I

decreases expression

ISO

Glyphosate results in decreased expression of UBE2I protein

NCBI chr10:14,782,245...14,802,911
Ensembl chr10:70,199,041...70,199,866
Ensembl chr10:70,199,041...70,199,866

G

ubiquitin-conjugating enzyme E2L 6

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of UBE2L6 mRNA

NCBI chr 3:90,279,705...90,294,721
Ensembl chr 3:90,279,668...90,294,717

G

ubiquitin-conjugating enzyme E2W

affects methylation
multiple interactions

ISO

Glyphosate affects the methylation of UBE2W gene
[Glyphosate results in increased abundance of aminomethylphosphonic acid (AMPA)] which affects the methylation of UBE2W gene

NCBI chr 5:7,474,039...7,531,526
Ensembl chr 5:7,474,003...7,598,245

G

ubiquitin protein ligase E3 component n-recognin 4

affects methylation

EXP

Glyphosate affects the methylation of UBR4 gene

NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:156,919,085...157,027,127

G

ubiquitin protein ligase E3 component n-recognin 5

affects methylation

EXP

Glyphosate affects the methylation of UBR5 gene

NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:71,000,197...71,109,813

G

UBX domain protein 8

decreases expression

EXP

Glyphosate results in decreased expression of UBXN8 mRNA

NCBI chr16:65,239,149...65,260,743
Ensembl chr16:65,240,062...65,260,639

G

ubiquitin C-terminal hydrolase L1

decreases expression

ISO

Glyphosate results in decreased expression of UCHL1 protein

NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417

G

uridine-cytidine kinase 1-like 1

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UCKL1 mRNA

NCBI chr 3:189,052,365...189,064,939
Ensembl chr 3:189,052,365...189,064,967

G

UDP-glucose 6-dehydrogenase

increases expression

ISO

Glyphosate results in increased expression of UGDH protein

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629

G

UDP glucuronosyltransferase 1 family, polypeptide A7C

increases expression

EXP

Glyphosate results in increased expression of UGT1A7C mRNA

NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

ubiquitin-like with PHD and ring finger domains 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of UHRF1 mRNA

NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792

G

unc-51 like kinase 3

decreases methylation

EXP

Glyphosate results in decreased methylation of ULK3 gene

NCBI chr 8:66,888,820...66,895,380
Ensembl chr 8:66,888,788...66,895,379

G

uromodulin-like 1

increases methylation
affects methylation

EXP

Glyphosate results in increased methylation of UMODL1 gene
Glyphosate affects the methylation of UMODL1 gene

PMID:31011160 PMID:35440735

NCBI chr20:9,029,025...9,088,510
Ensembl chr20:9,029,128...9,086,613

G

unc-45 myosin chaperone A

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UNC45A mRNA

NCBI chr 1:143,691,183...143,705,944
Ensembl chr 1:143,691,186...143,707,312

G

unc-5 netrin receptor C

increases expression
affects methylation

ISO
EXP

Glyphosate results in increased expression of UNC5C mRNA
Glyphosate affects the methylation of UNC5C gene

PMID:35440735 PMID:35489704

NCBI chr 2:232,854,352...233,208,482
Ensembl chr 2:232,846,262...233,208,482

G

unc-79 homolog, NALCN channel complex subunit

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of UNC79 gene
Glyphosate results in increased methylation of UNC79 gene

PMID:31011160 PMID:35440735

NCBI chr 6:127,841,671...128,092,380
Ensembl chr 6:127,848,074...128,092,995

G

uracil-DNA glycosylase

decreases expression

ISO

Glyphosate results in decreased expression of UNG mRNA

NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257

G

urate oxidase

multiple interactions
decreases methylation

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UOX mRNA
Glyphosate results in decreased methylation of UOX gene

PMID:31011160 PMID:33854195

NCBI chr 2:238,147,130...238,183,320
Ensembl chr 2:238,083,686...238,183,370

G

ubiquinol-cytochrome c reductase, complex III subunit X

decreases expression

ISO

Glyphosate results in decreased expression of UQCR10 mRNA

NCBI chr14:83,789,657...83,791,914
Ensembl chr14:83,789,658...83,791,914

G

urate (5-hydroxyiso-) hydrolase

decreases methylation

EXP

Glyphosate results in decreased methylation of URAH gene

NCBI chr 1:205,335,399...205,338,795
Ensembl chr 1:205,335,399...205,338,795

G

USH1 protein network component harmonin

decreases expression

EXP

Glyphosate results in decreased expression of USH1C mRNA

NCBI chr 1:105,831,719...105,880,082
Ensembl chr 1:105,831,723...105,880,082

G

usherin

affects methylation
increases methylation

EXP

Glyphosate affects the methylation of USH2A gene
Glyphosate results in increased methylation of USH2A gene

PMID:31011160 PMID:35440735

NCBI chr13:102,368,783...103,035,230
Ensembl chr13:102,368,783...103,035,217

G

USO1 vesicle transport factor

increases expression

ISO

Glyphosate results in increased expression of USO1 protein

NCBI chr14:16,150,921...16,216,389
Ensembl chr14:16,150,923...16,216,389

G

ubiquitin specific peptidase 13

decreases expression

ISO

Glyphosate results in decreased expression of USP13 mRNA

NCBI chr 2:117,502,811...117,617,049
Ensembl chr 2:117,505,122...117,630,161

G

ubiquitin specific peptidase 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of USP2 mRNA

NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:53,308,303...53,336,794

G

ubiquitin specific peptidase 29

increases expression

ISO

Glyphosate results in increased expression of USP29 mRNA

NCBI chr 1:75,907,331...75,959,896
Ensembl chr 1:75,906,632...76,131,141

G

ubiquitin specific peptidase 30

increases methylation

EXP

Glyphosate results in increased methylation of USP30 gene

NCBI chr12:48,161,905...48,215,878
Ensembl chr12:48,161,908...48,215,968

G

ubiquitin specific peptidase 40

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA

NCBI chr 9:96,055,741...96,126,766
Ensembl chr 9:96,055,741...96,126,721

G

ubiquitin specific peptidase 54

increases expression

ISO

Glyphosate results in increased expression of USP54 mRNA

NCBI chr15:3,706,013...3,806,935
Ensembl chr15:3,741,311...3,806,932

G

ubiquitin specific peptidase 9, Y-linked

decreases expression

ISO

Glyphosate results in decreased expression of USP9Y mRNA

NCBI chr Y:1,231,079...1,375,897
Ensembl chr Y:1,231,079...1,374,220

G

uronyl-2-sulfotransferase

affects methylation

EXP

Glyphosate affects the methylation of UST gene

NCBI chr 1:4,487,316...4,782,579
Ensembl chr 1:4,489,925...4,782,356

G

UTP20 small subunit processome component

affects methylation

EXP

Glyphosate affects the methylation of UTP20 gene

NCBI chr 7:25,022,029...25,103,024
Ensembl chr 7:25,022,036...25,103,041

G

utrophin

increases methylation

EXP

Glyphosate results in increased methylation of UTRN gene

NCBI chr 1:8,541,061...9,044,487
Ensembl chr 1:8,542,798...9,044,487

G

VANGL planar cell polarity protein 1

decreases expression

ISO

Glyphosate results in decreased expression of VANGL1 mRNA

NCBI chr 2:192,277,762...192,326,151
Ensembl chr 2:192,280,422...192,326,186

G

vav guanine nucleotide exchange factor 3

affects methylation

EXP

Glyphosate affects the methylation of VAV3 gene

NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:199,700,445...200,042,343

G

vascular endothelial growth factor A

increases expression
decreases expression
affects expression
multiple interactions

ISO
EXP

Glyphosate results in increased expression of VEGFA mRNA
Glyphosate results in decreased expression of VEGFA mRNA
Glyphosate affects the expression of VEGFA protein
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of VEGFA mRNA

PMID:31295307 PMID:33854195 PMID:34953950 PMID:38763501

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

vimentin

decreases expression

ISO

Glyphosate results in decreased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

G

vitelline membrane outer layer 1 homolog

affects methylation

ISO

Glyphosate affects the methylation of VMO1 gene

NCBI chr10:55,726,572...55,733,432
Ensembl chr10:55,726,572...55,727,856

G

vanin 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VNN3 mRNA

NCBI chr 1:23,390,596...23,402,858
Ensembl chr 1:23,390,596...23,402,858

G

vomeronasal 1 receptor 56

affects methylation

EXP

Glyphosate affects the methylation of VOM1R56 gene

NCBI chr 1:82,943,580...82,947,319

G

vomeronasal 1 receptor 73

decreases methylation

EXP

Glyphosate results in decreased methylation of VOM1R73 gene

NCBI chr 4:88,014,940...88,015,857
Ensembl chr 4:88,014,940...88,015,857

G

vomeronasal 1 receptor 84

affects methylation

EXP

Glyphosate affects the methylation of VOM1R84 gene

NCBI chr 4:88,466,236...88,467,144
Ensembl chr 4:88,466,236...88,467,144

G

vomeronasal 2 receptor, pseudogene 41

affects methylation

EXP

Glyphosate affects the methylation of VOM2R-PS41 gene

NCBI chr 1:73,960,668...73,973,414

G

vomeronasal 2 receptor, 58

affects methylation

EXP

Glyphosate affects the methylation of VOM2R58 gene

NCBI chr12:8,194,249...8,301,162
Ensembl chr12:8,194,249...8,301,162

G

VOPP1 WW domain binding protein

affects methylation

EXP

Glyphosate affects the methylation of VOPP1 gene

NCBI chr 4:88,692,784...88,762,903
Ensembl chr 4:88,693,837...88,780,528

G

V-set pre-B cell surrogate light chain 3

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of VPREB3 mRNA

NCBI chr20:12,716,862...12,720,108

G

vacuolar protein sorting 13 homolog B

affects methylation

EXP

Glyphosate affects the methylation of VPS13B gene

NCBI chr 7:68,436,996...69,013,574
Ensembl chr 7:68,443,655...69,013,574

G

vacuolar protein sorting 25 homolog

decreases expression

ISO

Glyphosate results in decreased expression of VPS25 mRNA

NCBI chr10:86,696,330...86,701,871
Ensembl chr10:86,696,157...86,701,871

G

VPS37B subunit of ESCRT-I

decreases expression

ISO

Glyphosate results in decreased expression of VPS37B mRNA

NCBI chr12:38,220,973...38,249,935
Ensembl chr12:38,220,959...38,249,935

G

VPS37D subunit of ESCRT-I

increases methylation

EXP

Glyphosate results in increased methylation of VPS37D gene

NCBI chr12:27,245,755...27,251,214
Ensembl chr12:27,245,625...27,251,213

G

vacuolar protein sorting 54 homolog (S. cerevisiae), pseudogene 1

affects methylation

EXP

Glyphosate affects the methylation of VPS54-PS1 gene

NCBI chr 7:59,717,663...59,720,016

G

vitronectin

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VTN mRNA

NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860

G

von Willebrand factor A domain containing 5B1

decreases expression

EXP

Glyphosate results in decreased expression of VWA5B1 mRNA

NCBI chr 5:156,080,599...156,148,155
Ensembl chr 5:156,080,039...156,135,799

G

von Willebrand factor C domain containing 2 like

increases expression

ISO

Glyphosate results in increased expression of VWC2L mRNA

NCBI chr 9:79,702,396...79,897,153
Ensembl chr 9:79,702,908...79,897,151

G

WASP family member 2

increases expression

ISO

Glyphosate results in increased expression of WASF2 mRNA

NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:150,620,733...150,685,943

G

WASP family member 3

increases methylation

EXP

Glyphosate results in increased methylation of WASF3 gene

NCBI chr12:13,675,642...13,774,648
Ensembl chr12:13,675,645...13,774,559

G

WD repeat and FYVE domain containing 3

affects methylation

EXP

Glyphosate affects the methylation of WDFY3 gene

NCBI chr14:7,873,946...8,115,002
Ensembl chr14:7,911,151...8,114,993

G

WD repeat domain 11

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of WDR11 gene

NCBI chr 1:193,595,606...193,641,149
Ensembl chr 1:193,595,535...193,641,142

G

WD repeat domain 59

affects methylation

EXP

Glyphosate affects the methylation of WDR59 gene

NCBI chr19:56,321,529...56,393,195
Ensembl chr19:56,325,438...56,393,132

G

WD repeat domain 86

decreases expression

EXP

Glyphosate results in decreased expression of WDR86 mRNA

NCBI chr 4:11,315,826...11,335,932
Ensembl chr 4:11,316,534...11,335,932

G

WEE1 G2 checkpoint kinase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of WEE1 mRNA

NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449

G

WAP four-disulfide core domain 9

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of WFDC9 gene

NCBI chr 3:173,799,888...173,808,383
Ensembl chr 3:173,799,888...173,803,066

G

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

multiple interactions
decreases expression

ISO
EXP

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of WFIKKN2 mRNA
Glyphosate results in decreased expression of WFIKKN2 mRNA

PMID:37567420 PMID:38314887

NCBI chr10:79,682,459...79,688,553
Ensembl chr10:79,682,459...79,688,553

G

WAS/WASL interacting protein family, member 1

affects methylation

EXP

Glyphosate affects the methylation of WIPF1 gene

NCBI chr 3:78,721,486...78,824,199
Ensembl chr 3:78,714,299...78,780,277

G

WAS/WASL interacting protein family, member 3

increases methylation

EXP

Glyphosate results in increased methylation of WIPF3 gene

NCBI chr 4:84,880,403...84,960,250
Ensembl chr 4:84,880,740...84,961,524

G

WNK lysine deficient protein kinase 3

affects methylation

EXP

Glyphosate affects the methylation of WNK3 gene

NCBI chr X:23,599,278...23,742,290
Ensembl chr X:23,599,305...23,742,290

G

Wnt family member 3A

increases expression

ISO

Glyphosate results in increased expression of WNT3A mRNA

NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919

G

Wnt family member 5A

increases expression
decreases response to substance
decreases expression
affects expression

ISO
EXP

Glyphosate results in increased expression of WNT5A mRNA
WNT5A protein results in decreased susceptibility to Glyphosate
Glyphosate results in decreased expression of WNT5A mRNA; Glyphosate results in decreased expression of WNT5A protein
Glyphosate affects the expression of WNT5A protein

PMID:26688330 PMID:28780397 PMID:31874349

NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860

G

Wnt family member 7A

increases expression
decreases expression

EXP
ISO

Glyphosate results in increased expression of WNT7A protein
Glyphosate results in increased expression of WNT7A mRNA
Glyphosate results in decreased expression of WNT7A protein

PMID:27287056 PMID:28780397 PMID:31874349

NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149

G

Wnt family member 9A

decreases expression

ISO

Glyphosate results in decreased expression of WNT9A mRNA

NCBI chr10:44,593,691...44,620,682
Ensembl chr10:44,593,691...44,620,682

G

Wnt family member 9B

affects methylation

EXP

Glyphosate affects the methylation of WNT9B gene

NCBI chr10:89,135,362...89,157,065
Ensembl chr10:89,135,363...89,157,065

G

WSC domain containing 2

increases methylation

EXP

Glyphosate results in increased methylation of WSCD2 gene

NCBI chr12:48,707,056...48,801,443
Ensembl chr12:48,707,056...48,801,319

G

XIAP associated factor 1

increases expression
multiple interactions

ISO

Glyphosate results in increased expression of XAF1 mRNA; Glyphosate results in increased expression of XAF1 protein
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of XAF1 mRNA; XAF1 protein affects the reaction [Glyphosate results in decreased expression of XIAP protein]; XAF1 protein affects the reaction [Glyphosate results in increased cleavage of CASP3 protein]; XAF1 protein affects the reaction [Glyphosate results in increased cleavage of PARP1 protein]; XAF1 protein affects the reaction [Glyphosate results in increased expression of BAX protein]

PMID:29908847 PMID:37567420

NCBI chr10:57,415,935...57,428,348
Ensembl chr10:57,415,658...57,428,349

G

X-C motif chemokine receptor 1

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of XCR1 mRNA

NCBI chr 8:132,357,020...132,393,596
Ensembl chr 8:132,357,020...132,385,862

G

X-linked inhibitor of apoptosis

multiple interactions
decreases expression
increases expression

ISO

[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of XIAP mRNA
Glyphosate results in decreased expression of XIAP protein
XAF1 protein affects the reaction [Glyphosate results in decreased expression of XIAP protein]
Glyphosate results in increased expression of XIAP mRNA

PMID:29908847 PMID:31874349 PMID:32800223

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978

G

XK related 9

decreases expression

ISO

Glyphosate results in decreased expression of XKR9 mRNA

NCBI chr 5:10,316,510...10,345,253
Ensembl chr 5:10,316,513...10,345,253

G

xylosyltransferase 1

affects methylation

EXP

Glyphosate affects the methylation of XYLT1 gene

NCBI chr 1:181,078,222...181,361,047
Ensembl chr 1:181,078,222...181,361,047

G

Yes1 associated transcriptional regulator

increases methylation

EXP

Glyphosate results in increased methylation of YAP1 gene

NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437

G

YOD1 deubiquitinase

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of YOD1 gene

NCBI chr13:44,727,319...44,733,933

G

YTH N6-methyladenosine RNA binding protein F3

increases expression

ISO

Glyphosate results in increased expression of YTHDF3 protein

NCBI chr 2:100,266,942...100,300,896
Ensembl chr 2:100,266,875...100,300,509

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

decreases expression

ISO

Glyphosate results in decreased expression of YWHAB protein
Glyphosate results in decreased expression of YWHAB mRNA

PMID:31295307 PMID:36173347

NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

decreases expression

ISO

Glyphosate results in decreased expression of YWHAQ mRNA

NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875

G

zygote arrest 1

increases expression

ISO

Glyphosate results in increased expression of ZAR1 mRNA

NCBI chr14:35,547,467...35,551,757
Ensembl chr14:35,547,467...35,551,611

G

zinc finger and BTB domain containing 12

increases methylation

EXP

Glyphosate results in increased methylation of ZBTB12 gene

NCBI chr20:3,942,302...3,945,148
Ensembl chr20:3,941,411...3,945,020

G

zinc finger and BTB domain containing 20

decreases methylation

EXP

Glyphosate results in decreased methylation of ZBTB20 gene

NCBI chr11:70,558,010...71,297,039
Ensembl chr11:70,580,930...70,736,237

G

zinc finger and BTB domain containing 2 like 1

decreases expression

EXP

Glyphosate results in decreased expression of ZBTB2L1 mRNA

NCBI chr 1:43,260,574...43,265,252

G

zinc finger and BTB domain containing 46

increases methylation

EXP

Glyphosate results in increased methylation of ZBTB46 gene

NCBI chr 3:188,874,826...188,949,005
Ensembl chr 3:188,877,117...188,913,033

G

zinc finger and BTB domain containing 7C

decreases expression

EXP

Glyphosate results in decreased expression of ZBTB7C mRNA

NCBI chr18:71,716,586...72,045,831
Ensembl chr18:71,716,623...72,040,339

G

zinc finger, C2HC-type containing 1C

increases expression
decreases expression

ISO
EXP

Glyphosate results in increased expression of ZC2HC1C mRNA
Glyphosate results in decreased expression of ZC2HC1C mRNA

PMID:33713393 PMID:38314887

NCBI chr 6:110,663,682...110,672,606
Ensembl chr 6:110,663,641...110,674,083

G

zinc finger CCHC-type containing 24

increases expression

ISO

Glyphosate results in increased expression of ZCCHC24 mRNA

NCBI chr16:1,281,350...1,333,278
Ensembl chr16:1,281,350...1,333,350

G

zinc finger, DBF-type containing 2

increases expression

ISO

Glyphosate results in increased expression of ZDBF2 mRNA

NCBI chr 9:72,203,598...72,242,287
Ensembl chr 9:72,203,598...72,242,287

G

zinc finger DHHC-type palmitoyltransferase 14

affects methylation

EXP

Glyphosate affects the methylation of ZDHHC14 gene

NCBI chr 1:48,473,860...48,746,201
Ensembl chr 1:48,474,274...48,744,413

G

zinc finger DHHC-type palmitoyltransferase 2

affects methylation

EXP

Glyphosate affects the methylation of ZDHHC2 gene

NCBI chr16:58,511,931...58,581,530
Ensembl chr16:58,511,934...58,581,516

G

zinc finger DHHC-type palmitoyltransferase 20

affects methylation
increases expression

EXP
ISO

Glyphosate affects the methylation of ZDHHC20 gene
Glyphosate results in increased expression of ZDHHC20 mRNA

PMID:35440735 PMID:35897073

NCBI chr15:36,095,624...36,154,546
Ensembl chr15:36,098,282...36,154,532

G

zinc finger and AT hook domain containing

affects methylation

EXP

Glyphosate affects the methylation of ZFAT gene

NCBI chr 7:101,775,916...101,951,135
Ensembl chr 7:101,775,916...101,943,237

G

zinc finger, C3H1-type containing

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFC3H1 mRNA

NCBI chr 7:52,894,417...52,950,755
Ensembl chr 7:52,894,172...52,950,758

G

zinc finger homeobox 3

decreases methylation

EXP

Glyphosate results in decreased methylation of ZFHX3 gene

NCBI chr19:52,789,146...53,795,664
Ensembl chr19:53,551,488...53,795,664

G

zinc finger homeobox 3 like

decreases expression

EXP

Glyphosate results in decreased expression of ZFHX3L mRNA

NCBI chr19:53,533,868...53,541,731

G

zinc finger protein 13

decreases expression

ISO

Glyphosate results in decreased expression of ZFP13 mRNA

NCBI chr10:13,119,707...13,128,284
Ensembl chr10:13,120,084...13,128,243

G

zinc finger protein (C2H2 type) 276

increases expression

ISO

Glyphosate results in increased expression of ZFP276 mRNA

NCBI chr19:68,199,709...68,212,757
Ensembl chr19:68,199,265...68,212,757

G

zinc finger protein 277

increases methylation

EXP

Glyphosate results in increased methylation of ZFP277 gene

NCBI chr 6:63,110,609...63,239,941
Ensembl chr 6:63,110,609...63,239,831

G

zinc finger protein 280D

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP280D mRNA

NCBI chr 8:81,872,108...81,961,194
Ensembl chr 8:81,873,335...81,961,201

G

zinc finger protein 36, C3H type-like 1

decreases expression

ISO

Glyphosate results in decreased expression of ZFP36L1 mRNA

NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979

G

zinc finger protein 36, C3H type-like 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP36L2 mRNA

NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653

G

zinc finger protein 385D

affects methylation

EXP

Glyphosate affects the methylation of ZFP385D gene

NCBI chr15:7,473,431...7,854,364
Ensembl chr15:7,473,435...8,504,582

G

zinc finger protein 422

increases expression
multiple interactions

EXP

Glyphosate results in increased expression of ZFP422 mRNA
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP422 mRNA

PMID:33854195 PMID:34850229

NCBI chr 4:151,558,254...151,565,730
Ensembl chr 4:151,556,738...151,566,152

G

zinc finger protein 449

increases methylation

EXP

Glyphosate results in increased methylation of ZFP449 gene

NCBI chr X:139,127,425...139,147,490
Ensembl chr X:139,127,479...139,147,489

G

zinc finger protein 455

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP455 mRNA

NCBI chr 2:86,326,568...86,445,514
Ensembl chr 2:86,426,916...86,441,874

G

zinc finger protein 473

decreases expression

EXP

Glyphosate results in decreased expression of ZFP473 mRNA

NCBI chr 1:104,358,757...104,379,833
Ensembl chr 1:104,359,709...104,379,775

G

zinc finger protein 475

affects methylation

EXP

Glyphosate affects the methylation of ZFP475 gene

NCBI chr18:48,276,106...48,297,562

G

zinc finger protein 516

increases expression
affects methylation

ISO
EXP

Glyphosate results in increased expression of ZFP516 mRNA
Glyphosate affects the methylation of ZFP516 gene

PMID:35440735 PMID:35897073

NCBI chr18:78,561,069...78,661,263
Ensembl chr18:78,573,562...78,674,419

G

zinc finger protein 52

affects methylation

EXP

Glyphosate affects the methylation of ZFP52 gene

NCBI chr 1:69,998,534...70,036,017
Ensembl chr 1:70,015,922...70,036,870

G

zinc finger protein 536

increases expression
decreases methylation

ISO
EXP

Glyphosate results in increased expression of ZFP536 mRNA
Glyphosate results in decreased methylation of ZFP536 gene

PMID:31011160 PMID:35897073

NCBI chr 1:99,137,133...99,600,379
Ensembl chr 1:99,137,133...99,599,043

G

zinc finger protein 598

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP598 mRNA

NCBI chr10:14,198,763...14,210,773
Ensembl chr10:14,185,611...14,210,772

G

zinc finger protein 605 like 1

increases expression

EXP

Glyphosate results in increased expression of ZFP605L1 mRNA

NCBI chr18:29,731,712...29,732,477
Ensembl chr12:52,228,260...52,228,619

G

zinc finger protein 683

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ZFP683 mRNA

NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:151,561,480...151,569,764

G

zinc finger protein 78

decreases expression

ISO

Glyphosate results in decreased expression of ZFP78 mRNA

NCBI chr 1:76,543,519...76,558,052

G

zinc finger protein 804B

affects methylation

EXP

Glyphosate affects the methylation of ZFP804B gene

NCBI chr 4:27,563,948...28,099,625
Ensembl chr 4:27,564,465...28,097,319

G

zinc finger FYVE-type containing 16

increases methylation

EXP

Glyphosate results in increased methylation of ZFYVE16 gene

NCBI chr 2:25,448,264...25,495,180
Ensembl chr 2:25,448,829...25,483,295

G

zinc finger FYVE-type containing 27

increases expression

ISO

Glyphosate results in increased expression of ZFYVE27 mRNA

NCBI chr 1:250,929,110...250,952,481
Ensembl chr 1:250,928,012...250,952,481

G

zinc finger FYVE-type containing 28

affects methylation

EXP

Glyphosate affects the methylation of ZFYVE28 gene

NCBI chr14:80,692,997...80,778,606
Ensembl chr14:80,692,819...80,778,586

G

zinc finger, GRF-type containing 1

affects methylation

EXP

Glyphosate affects the methylation of ZGRF1 gene

NCBI chr 2:218,687,413...218,750,104
Ensembl chr 2:218,687,505...218,750,104

G

zinc finger with KRAB and SCAN domains 2

multiple interactions

ISO

[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of ZKSCAN2 mRNA

NCBI chr 1:187,437,095...187,459,300
Ensembl chr 1:187,440,330...187,458,985

G

zinc finger MYM-type containing 3

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM3 mRNA

NCBI chr X:70,568,573...70,584,221
Ensembl chr X:70,568,573...70,584,768

G

zinc finger MYM-type containing 6

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM6 mRNA

NCBI chr 5:144,680,819...144,728,805
Ensembl chr 5:144,681,197...144,728,803

G

zinc finger protein 726 like, pseudogene 1

increases expression

EXP

Glyphosate results in increased expression of ZNF726L-PS1 mRNA

NCBI chr 1:36,774,025...36,782,368

G

zona pellucida glycoprotein 2

decreases expression

ISO

Glyphosate results in decreased expression of ZP2 protein

NCBI chr 1:183,944,840...183,956,619
Ensembl chr 1:183,939,880...183,963,075

G

zinc finger RANBP2-type containing 2

multiple interactions

EXP

[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZRANB2 mRNA

NCBI chr 2:249,232,010...249,245,786
Ensembl chr 2:249,232,010...249,245,780

G

zinc finger, SWIM-type containing 4

affects methylation

EXP

Glyphosate affects the methylation of ZSWIM4 gene

NCBI chr19:40,832,608...40,857,742
Ensembl chr19:40,832,635...40,857,742

hypochlorous acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ABCC1 mRNA

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily D member 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ABCD1 mRNA

NCBI chr X:156,579,669...156,601,448
Ensembl chr X:156,579,785...156,601,446

G

abhydrolase domain containing 16A, phospholipase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ABHD16A mRNA

NCBI chr20:3,723,756...3,738,617
Ensembl chr20:3,723,757...3,738,736

G

acyl-CoA dehydrogenase short chain

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ACADS mRNA

NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103

G

acyl-CoA binding domain containing 4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ACBD4 mRNA

NCBI chr10:88,548,146...88,558,588
Ensembl chr10:88,548,158...88,558,587

G

acetylcholinesterase

multiple interactions
decreases activity

ISO

[Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein; Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein]

PMID:12414318 PMID:36924976

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

ISO

Hypochlorous Acid results in increased expression of ADRM1 mRNA

NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483

G

alpha-fetoprotein

increases expression

ISO

Hypochlorous Acid results in increased expression of AFP mRNA

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

agrin

decreases expression

ISO

Hypochlorous Acid results in decreased expression of AGRN mRNA

NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539

G

aldo-keto reductase family 1 member A1

increases expression

ISO

Hypochlorous Acid results in increased expression of AKR1A1 mRNA

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldo-keto reductase family 1 member B1

increases expression

ISO

Hypochlorous Acid results in increased expression of AKR1B1 mRNA

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 7, member A2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of AKR7A5 mRNA

NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109

G

aldehyde dehydrogenase 1 family, member A3

increases expression

ISO

Hypochlorous Acid results in increased expression of ALDH1A3 mRNA

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777

G

angiomotin-like 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of AMOTL1 mRNA

NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869

G

adenosine monophosphate deaminase 1

increases activity
multiple interactions

ISO

Hypochlorous Acid results in increased activity of AMPD1 protein
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein]

NCBI chr 2:193,287,219...193,308,446
Ensembl chr 2:193,287,265...193,308,443

G

angel homolog 2

increases expression

ISO

Hypochlorous Acid results in increased expression of ANGEL2 mRNA

NCBI chr13:105,041,727...105,060,640
Ensembl chr13:105,041,728...105,060,640

G

ankyrin repeat and IBR domain containing 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ANKIB1 mRNA

NCBI chr 4:31,288,393...31,412,500
Ensembl chr 4:31,288,142...31,412,504

G

ankyrin repeat domain containing 11

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ANKRD11 mRNA

NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491

G

ankyrin repeat domain 13D

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ANKRD13D mRNA

NCBI chr 1:210,995,012...211,007,430
Ensembl chr 1:210,995,148...211,007,369

G

adaptor related protein complex 1 subunit gamma 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of AP1G2 mRNA

NCBI chr15:32,541,528...32,549,392
Ensembl chr15:32,541,528...32,549,280

G

adaptor related protein complex 3 subunit sigma 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of AP3S2 mRNA

NCBI chr 1:143,228,131...143,268,573
Ensembl chr 1:143,228,135...143,268,573

G

acylaminoacyl-peptide hydrolase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of APEH mRNA

NCBI chr 8:117,652,390...117,661,502
Ensembl chr 8:117,652,393...117,661,711

G

apurinic/apyrimidinic endodeoxyribonuclease 1

multiple interactions
increases expression
increases activity

ISO

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein]
Hypochlorous Acid results in increased activity of APEX1 protein

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

apoptosis inhibitor 5

increases expression

ISO

Hypochlorous Acid results in increased expression of API5 mRNA

NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580

G

apolipoprotein A1

multiple interactions

ISO

[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein; Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729

G

amyloid beta precursor protein binding protein 2

increases expression

ISO

Hypochlorous Acid results in increased expression of APPBP2 mRNA

NCBI chr10:70,555,212...70,597,267
Ensembl chr10:70,555,212...70,597,193

G

archain 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ARCN1 mRNA

NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005

G

Rho GTPase activating protein 24

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ARHGAP24 mRNA

NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950

G

Rho guanine nucleotide exchange factor 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ARHGEF1 mRNA

NCBI chr 1:89,626,884...89,648,823
Ensembl chr 1:89,628,266...89,649,067

G

ariadne RBR E3 ubiquitin protein ligase 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ARIH1 mRNA

NCBI chr 8:68,673,199...68,775,648
Ensembl chr 8:68,673,200...68,775,572

G

ARF like GTPase 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ARL2 mRNA

NCBI chr 1:212,863,422...212,875,425
Ensembl chr 1:212,863,423...212,875,373

G

ataxin 3

increases expression

ISO

Hypochlorous Acid results in increased expression of ATXN3 mRNA

NCBI chr 6:126,837,107...126,872,919
Ensembl chr 6:126,839,327...126,872,781

G

beta-1,3-glucuronyltransferase 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of B3GAT3 mRNA

NCBI chr 1:215,246,453...215,253,033
Ensembl chr 1:215,246,482...215,266,876

G

beta-secretase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BACE1 mRNA

NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918

G

branched chain ketoacid dehydrogenase kinase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BCKDK mRNA

NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453

G

BCL2-associated transcription factor 1

increases expression

ISO

Hypochlorous Acid results in increased expression of BCLAF1 mRNA

NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801

G

basic helix-loop-helix family, member e40

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BHLHE40 mRNA

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783

G

biliverdin reductase B

increases expression

ISO

Hypochlorous Acid results in increased expression of BLVRB mRNA

NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225

G

bromodomain containing 4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BRD4 mRNA

NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923

G

bromodomain containing 8

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BRD8 mRNA

NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006

G

brain protein I3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BRI3 mRNA

NCBI chr12:15,454,673...15,478,319
Ensembl chr12:15,454,673...15,478,319

G

BRMS1, transcriptional repressor and anoikis regulator

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BRMS1 mRNA

NCBI chr 1:211,775,142...211,784,411
Ensembl chr 1:211,775,095...211,784,410

G

BTB domain containing 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of BTBD2 mRNA

NCBI chr 7:9,710,392...9,726,032
Ensembl chr 7:9,712,269...9,726,032

G

basic leucine zipper and W2 domains 1

increases expression

ISO

Hypochlorous Acid results in increased expression of BZW1 mRNA

NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684

G

carbonic anhydrase 12

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CAR12 mRNA

NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465

G

calcium binding protein 39

increases expression

ISO

Hypochlorous Acid results in increased expression of CAB39 mRNA

NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542

G

calcium/calmodulin-dependent protein kinase ID

increases expression

ISO

Hypochlorous Acid results in increased expression of CAMK1D mRNA

NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012

G

calnexin

increases expression

ISO

Hypochlorous Acid results in increased expression of CANX mRNA

NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857

G

calpain 5

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CAPN5 mRNA

NCBI chr 1:161,827,474...161,884,142
Ensembl chr 1:161,827,474...161,884,142

G

catalase

multiple interactions
increases activity
increases expression

ISO

CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]
Hypochlorous Acid results in increased activity of CAT protein
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein]
Hypochlorous Acid results in increased expression of CAT mRNA

PMID:17980396 PMID:19376150 PMID:36924976

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cyclin D3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CCND3 mRNA

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033

G

Cd47 molecule

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CD47 mRNA

NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272

G

cell division cycle 42

increases expression

ISO

Hypochlorous Acid results in increased expression of CDC42 mRNA

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627

G

cell division cycle associated 7 like

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CDCA7L mRNA

NCBI chr 6:144,936,885...144,982,844
Ensembl chr 6:144,908,171...144,982,843

G

CDK5 regulatory subunit associated protein 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CDK5RAP3 mRNA

NCBI chr10:82,390,845...82,402,814
Ensembl chr10:82,390,845...82,400,001

G

cyclin-dependent kinase 6

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CDK6 mRNA

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701

G

cyclin-dependent kinase 7

increases expression

ISO

Hypochlorous Acid results in increased expression of CDK7 mRNA

NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485

G

CDP-diacylglycerol synthase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CDS1 mRNA

NCBI chr14:8,126,678...8,187,243
Ensembl chr14:8,124,838...8,187,218

G

CDP-diacylglycerol synthase 2

increases expression

ISO

Hypochlorous Acid results in increased expression of CDS2 mRNA

NCBI chr 3:139,967,870...140,006,459
Ensembl chr 3:139,967,742...140,009,201

G

centrosomal protein 43

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CEP43 mRNA

NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:55,082,712...55,111,509

G

centrosomal protein 76

increases expression

ISO

Hypochlorous Acid results in increased expression of CEP76 mRNA

NCBI chr18:63,444,389...63,478,358
Ensembl chr18:63,443,746...63,478,358

G

ceramide kinase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CERK mRNA

NCBI chr 7:119,105,674...119,149,885
Ensembl chr 7:119,105,674...119,148,570

G

chromodomain helicase DNA binding protein 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CHD3 mRNA

NCBI chr10:54,562,437...54,588,842
Ensembl chr10:54,562,437...54,588,810

G

chromodomain helicase DNA binding protein 4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CHD4 mRNA

NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:159,584,654...159,617,866

G

chitinase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CHIT1 mRNA

NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639

G

cysteine and histidine rich domain containing 1

increases expression

ISO

Hypochlorous Acid results in increased expression of CHORDC1 mRNA

NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696

G

C-type lectin domain family 4, member D

increases expression

ISO

Hypochlorous Acid results in increased expression of CLEC4D mRNA

NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:158,275,341...158,287,055

G

CLN6, transmembrane ER protein

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CLN6 mRNA

NCBI chr 8:72,198,773...72,213,777
Ensembl chr 8:72,198,712...72,213,776

G

clathrin, light chain A

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CLTA mRNA

NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215

G

collagen type I alpha 1 chain

increases expression
multiple interactions

ISO

Hypochlorous Acid results in increased expression of COL1A1 mRNA; Hypochlorous Acid results in increased expression of COL1A1 protein
Roflumilast inhibits the reaction [Hypochlorous Acid results in increased expression of COL1A1 mRNA]; Roflumilast inhibits the reaction [Hypochlorous Acid results in increased expression of COL1A1 protein]

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

coronin 1A

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CORO1A mRNA

NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102

G

CTD small phosphatase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CTDSP1 mRNA

NCBI chr 9:83,422,755...83,428,411
Ensembl chr 9:83,423,051...83,428,412

G

catenin, beta-interacting protein 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CTNNBIP1 mRNA

NCBI chr 5:165,245,019...165,293,994
Ensembl chr 5:165,245,098...165,293,991

G

cystinosin, lysosomal cystine transporter

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CTNS mRNA

NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661

G

cathepsin B

decreases expression

ISO

Hypochlorous Acid results in decreased expression of CTSB mRNA

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cullin 5

increases expression

ISO

Hypochlorous Acid results in increased expression of CUL5 mRNA

NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463

G

cytochrome P450, family 20, subfamily a, polypeptide 1

increases expression

ISO

Hypochlorous Acid results in increased expression of CYP20A1 mRNA

NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291

G

DAB adaptor protein 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888

G

DNA-damage inducible transcript 3

increases expression

ISO

Hypochlorous Acid results in increased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DEAD-box helicase 10

increases expression

ISO

Hypochlorous Acid results in increased expression of DDX10 mRNA

NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585

G

DEAD-box helicase 3, X-linked

increases expression

ISO

Hypochlorous Acid results in increased expression of DDX3X mRNA

NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983

G

DENN domain containing 1A

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DENND1A mRNA

NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886

G

DEAH-box helicase 33

increases expression

ISO

Hypochlorous Acid results in increased expression of DHX33 mRNA

NCBI chr10:56,206,680...56,223,189
Ensembl chr10:56,206,680...56,223,143

G

dihydrolipoamide S-succinyltransferase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DLST mRNA

NCBI chr 6:110,489,576...110,512,841
Ensembl chr 6:110,489,392...110,514,357

G

DnaJ heat shock protein family (Hsp40) member A2

increases expression

ISO

Hypochlorous Acid results in increased expression of DNAJA2 mRNA

NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120

G

DNA methyltransferase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DNMT1 mRNA

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119

G

DNA methyltransferase 3 like

increases expression

ISO

Hypochlorous Acid results in increased expression of DNMT3L mRNA

NCBI chr20:10,614,591...10,628,989
Ensembl chr20:10,614,591...10,629,168

G

deoxynucleotidyltransferase, terminal, interacting protein 2

increases expression

ISO

Hypochlorous Acid results in increased expression of DNTTIP2 mRNA

NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:213,058,962...213,071,016

G

down-regulator of transcription 1

increases expression

ISO

Hypochlorous Acid results in increased expression of DR1 mRNA

NCBI chr14:1,603,203...1,614,556
Ensembl chr14:1,603,204...1,614,556

G

dystrobrevin, beta

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DTNB mRNA

NCBI chr 6:32,286,022...32,483,007
Ensembl chr 6:32,285,941...32,485,872

G

DTW domain containing 2

increases expression

ISO

Hypochlorous Acid results in increased expression of DTWD2 mRNA

NCBI chr18:45,003,242...45,088,595
Ensembl chr18:45,003,644...45,088,419

G

deltex E3 ubiquitin ligase 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of DTX3 mRNA

NCBI chr 7:64,898,693...64,904,636
Ensembl chr 7:64,898,866...64,903,752

G

eukaryotic elongation factor, selenocysteine-tRNA-specific

decreases expression

ISO

Hypochlorous Acid results in decreased expression of EEFSEC mRNA

NCBI chr 4:122,276,907...122,473,049
Ensembl chr 4:122,263,535...122,473,049

G

epidermal growth factor receptor

multiple interactions

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

euchromatic histone lysine methyltransferase 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of EHMT2 mRNA

NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384

G

eukaryotic translation initiation factor 2D

decreases expression

ISO

Hypochlorous Acid results in decreased expression of LGTN mRNA

NCBI chr13:45,168,161...45,189,362
Ensembl chr13:45,139,967...45,191,974

G

eukaryotic translation initiation factor 5

increases expression

ISO

Hypochlorous Acid results in increased expression of EIF5 mRNA

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

elongin A

increases expression

ISO

Hypochlorous Acid results in increased expression of ELOA mRNA

NCBI chr 5:153,513,246...153,530,819
Ensembl chr 5:153,515,066...153,530,916

G

ERI1 exoribonuclease family member 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ERI3 mRNA

NCBI chr 5:136,252,691...136,379,832
Ensembl chr 5:136,252,683...136,379,815

G

endoplasmic reticulum protein 29

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ERP29 mRNA

NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010

G

establishment of sister chromatid cohesion N-acetyltransferase 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ESCO1 mRNA

NCBI chr18:1,904,748...1,959,609
Ensembl chr18:1,904,762...1,959,805

G

esterase D

increases expression

ISO

Hypochlorous Acid results in increased expression of ESD mRNA

NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508

G

exosome component 5

decreases expression

ISO

Hypochlorous Acid results in decreased expression of EXOSC5 mRNA

NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046

G

FA complementation group E

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FANCE mRNA

NCBI chr20:6,371,153...6,388,366
Ensembl chr20:6,377,234...6,388,365

G

Fas-activated serine/threonine kinase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FASTK mRNA

NCBI chr 4:11,624,697...11,628,769
Ensembl chr 4:11,624,689...11,629,867

G

F-box and leucine-rich repeat protein 3

increases expression

ISO

Hypochlorous Acid results in increased expression of FBXL3 mRNA

NCBI chr15:86,321,504...86,341,387
Ensembl chr15:86,321,504...86,341,387

G

F-box and WD repeat domain containing 5

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FBXW5 mRNA

NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235

G

F-box and WD repeat domain containing 7

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FBXW7 mRNA

NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:172,447,738...172,609,591

G

FGR proto-oncogene, Src family tyrosine kinase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FGR mRNA

NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:150,473,792...150,503,169

G

fukutin

increases expression

ISO

Hypochlorous Acid results in increased expression of FKTN mRNA

NCBI chr 5:73,134,746...73,191,772
Ensembl chr 5:73,135,361...73,189,181

G

fibronectin 1

increases expression
multiple interactions

ISO

Hypochlorous Acid results in increased expression of FN1 protein
Roflumilast inhibits the reaction [Hypochlorous Acid results in increased expression of FN1 protein]

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Hypochlorous Acid results in increased expression of FOS mRNA; Hypochlorous Acid results in increased expression of FOS protein

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FAD-dependent oxidoreductase domain containing 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of FOXRED1 mRNA

NCBI chr 8:41,789,557...41,818,064
Ensembl chr 8:41,808,843...41,817,980

G

ferritin light chain 1

increases expression

ISO

Hypochlorous Acid results in increased expression of FTL1 mRNA

NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915

G

glucose-6-phosphate dehydrogenase

multiple interactions
decreases activity

ISO

Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO

Hypochlorous Acid results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, beta

increases expression

ISO

Hypochlorous Acid results in increased expression of GADD45B mRNA

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

growth arrest and DNA-damage-inducible, gamma

increases expression

ISO

Hypochlorous Acid results in increased expression of GADD45G mRNA

NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369

G

galactokinase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of GALK1 mRNA

NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
affects expression
increases expression

ISO

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]
Hypochlorous Acid affects the expression of GCLC mRNA

PMID:17980396 PMID:18648578

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

increases expression

ISO

Hypochlorous Acid results in increased expression of GCLM mRNA

PMID:18156441 PMID:19376150

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

glia maturation factor, beta

increases expression

ISO

Hypochlorous Acid results in increased expression of GMFB mRNA

NCBI chr15:22,549,705...22,560,125
Ensembl chr15:22,547,034...22,560,308

G

G protein subunit alpha i3

increases expression

ISO

Hypochlorous Acid results in increased expression of GNAI3 mRNA

NCBI chr 2:198,430,920...198,468,874

G

G protein subunit beta 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of GNB2 mRNA

NCBI chr12:24,795,505...24,800,796
Ensembl chr12:24,795,827...24,800,796

G

golgi associated PDZ and coiled-coil motif containing

increases expression

ISO

Hypochlorous Acid results in increased expression of GOPC mRNA

NCBI chr20:32,270,314...32,319,635
Ensembl chr20:32,270,314...32,319,611

G

GC-rich promoter binding protein 1

increases expression

ISO

Hypochlorous Acid results in increased expression of GPBP1 mRNA

NCBI chr 2:44,756,861...44,824,281
Ensembl chr 2:44,756,861...44,824,315

G

glutathione peroxidase 1

decreases expression
increases activity
multiple interactions

ISO

Hypochlorous Acid results in decreased expression of GPX1 mRNA
Hypochlorous Acid results in increased activity of GPX1 protein
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein]

PMID:19376150 PMID:36924976

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione peroxidase 4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of GPX4 mRNA

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629

G

granulin precursor

decreases expression

ISO

Hypochlorous Acid results in decreased expression of GRN mRNA

NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936

G

glutathione-disulfide reductase

increases expression
multiple interactions
decreases activity

ISO

Hypochlorous Acid results in increased expression of GSR mRNA
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein]

PMID:17980396 PMID:36924976

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

increases expression

ISO

Hypochlorous Acid results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

H2B clustered histone 18

increases expression

ISO

Hypochlorous Acid results in increased expression of H2BC18 mRNA

NCBI chr 2:186,527,197...186,531,634

G

hydroxyacylglutathione hydrolase-like

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HAGHL mRNA

NCBI chr10:15,309,469...15,313,910
Ensembl chr10:15,308,668...15,312,181

G

HAUS augmin-like complex, subunit 4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HAUS4 mRNA

NCBI chr15:31,964,555...31,976,853
Ensembl chr15:31,964,556...31,975,941

G

histone deacetylase 10

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HDAC10 mRNA

NCBI chr 7:122,078,768...122,084,457
Ensembl chr 7:122,078,768...122,083,870

G

histone deacetylase 5

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HDAC5 mRNA

NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244

G

histone deacetylase 6

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HDAC6 mRNA

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:17,222,856...17,244,370

G

hexosaminidase D

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HEXD mRNA

NCBI chr10:106,978,426...107,002,252
Ensembl chr10:106,978,165...106,997,083

G

homeodomain interacting protein kinase 2

increases expression

ISO

Hypochlorous Acid results in increased expression of HIPK2 mRNA

NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:68,369,099...68,586,108

G

homeodomain interacting protein kinase 3

increases expression

ISO

Hypochlorous Acid results in increased expression of HIPK3 mRNA

NCBI chr 3:111,251,863...111,322,815
Ensembl chr 3:111,251,863...111,322,772

G

hexokinase 1

multiple interactions
decreases activity

ISO

Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein]

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

high mobility group AT-hook 2

increases expression

ISO

Hypochlorous Acid results in increased expression of HMGA2 mRNA

NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341

G

heme oxygenase 1

multiple interactions
increases expression

ISO

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA]
[Quercetin co-treated with Hypochlorous Acid] results in increased expression of HMOX1 protein
Hypochlorous Acid results in increased expression of HMOX1 mRNA; Hypochlorous Acid results in increased expression of HMOX1 protein

PMID:17980396 PMID:18156441 PMID:19376150 PMID:24017971

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

hippocalcin-like 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HPCAL1 mRNA

NCBI chr 6:46,206,809...46,313,364
Ensembl chr 6:46,260,494...46,313,353

G

hypoxanthine phosphoribosyltransferase 1

increases mutagenesis

ISO

Hypochlorous Acid results in increased mutagenesis of HPRT1 gene

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712

G

HPS1, biogenesis of lysosomal organelles complex 3 subunit 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of HPS1 mRNA

NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739

G

heat shock protein 90 alpha family class A member 1

increases expression

ISO

Hypochlorous Acid results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein family A (Hsp70) member 13

increases expression

ISO

Hypochlorous Acid results in increased expression of HSPA13 mRNA

NCBI chr11:27,862,717...27,876,898
Ensembl chr11:27,862,593...27,876,898

G

heat shock protein family A (Hsp70) member 1A

multiple interactions
increases expression

ISO

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1B

increases expression

ISO

Hypochlorous Acid results in increased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

interferon gamma

increases expression

ISO

Hypochlorous Acid results in increased expression of IFNG mRNA

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

increases expression

ISO

Hypochlorous Acid results in increased expression of IKBKG mRNA

NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757

G

interleukin 10

increases expression

ISO

Hypochlorous Acid results in increased expression of IL10 mRNA

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 1 beta

increases expression

ISO

Hypochlorous Acid results in increased expression of IL1B mRNA

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

increases expression

ISO

Hypochlorous Acid results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

inhibitor of growth family, member 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ING2 mRNA

NCBI chr16:51,305,311...51,316,177
Ensembl chr16:51,307,466...51,316,177

G

integrator complex subunit 7

decreases expression

ISO

Hypochlorous Acid results in decreased expression of INTS7 mRNA

NCBI chr13:105,686,208...105,739,609
Ensembl chr13:105,686,128...105,739,608

G

integrator complex subunit 8

increases expression

ISO

Hypochlorous Acid results in increased expression of INTS8 mRNA

NCBI chr 5:29,094,475...29,141,874
Ensembl chr 5:29,094,475...29,142,099

G

integrin subunit beta 5

decreases expression

ISO

Hypochlorous Acid results in decreased expression of ITGB5 mRNA

NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373

G

jagged canonical Notch ligand 1

increases expression

ISO

Hypochlorous Acid results in increased expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872

G

Janus kinase 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of JAK3 mRNA

NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222

G

kelch repeat and BTB domain containing 8

increases expression

ISO

Hypochlorous Acid results in increased expression of KBTBD8 mRNA

NCBI chr 4:129,232,781...129,245,608
Ensembl chr 4:129,232,027...129,245,605

G

Kelch-like ECH-associated protein 1

increases expression

ISO

Hypochlorous Acid results in increased expression of KEAP1 mRNA

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042

G

kinesin family member 1B

increases expression

ISO

Hypochlorous Acid results in increased expression of KIF1B mRNA

NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:164,894,763...165,008,841

G

kinesin family member 24

decreases expression

ISO

Hypochlorous Acid results in decreased expression of KIF24 mRNA

NCBI chr 5:61,357,078...61,423,882
Ensembl chr 5:61,357,940...61,399,379

G

kinesin family member 3C

increases expression

ISO

Hypochlorous Acid results in increased expression of KIF3C mRNA

NCBI chr 6:32,086,879...32,125,812
Ensembl chr 6:32,086,124...32,126,066

G

kinesin family member 5B

increases expression

ISO

Hypochlorous Acid results in increased expression of KIF5B mRNA

NCBI chr17:56,185,386...56,222,990
Ensembl chr17:56,185,380...56,223,008

G

karyopherin subunit alpha 1

increases expression

ISO

Hypochlorous Acid results in increased expression of KPNA1 mRNA

NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067

G

karyopherin subunit alpha 4

increases expression

ISO

Hypochlorous Acid results in increased expression of KPNA4 mRNA

NCBI chr 2:155,635,679...155,691,056
Ensembl chr 2:155,634,247...155,691,053

G

KRR1, small subunit processome component homolog

increases expression

ISO

Hypochlorous Acid results in increased expression of KRR1 mRNA

NCBI chr 7:49,361,794...49,374,222
Ensembl chr 7:49,361,901...49,374,216

G

lecithin cholesterol acyltransferase

multiple interactions

ISO

[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein

NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081

G

lactate dehydrogenase A

increases activity
multiple interactions

ISO

Hypochlorous Acid results in increased activity of LDHA protein
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

LIM domain containing 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of LIMD2 mRNA

NCBI chr10:91,590,079...91,592,747
Ensembl chr10:91,590,082...91,592,439

G

lipase maturation factor 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of LMF1 mRNA

NCBI chr10:15,094,432...15,188,665
Ensembl chr10:15,098,138...15,188,664

G

lysyl oxidase-like 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of LOXL3 mRNA

NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046

G

LDL receptor related protein 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of LRP1 mRNA

NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196

G

leucine rich repeat containing 8 VRAC subunit D

increases expression

ISO

Hypochlorous Acid results in increased expression of LRRC8D mRNA

NCBI chr14:4,335,114...4,411,549
Ensembl chr14:4,332,130...4,445,639

G

MAF bZIP transcription factor F

increases expression

ISO

Hypochlorous Acid results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

MAF bZIP transcription factor G

increases expression

ISO

Hypochlorous Acid results in increased expression of MAFG mRNA

NCBI chr10:106,401,633...106,410,159

G

mannosidase, alpha, class 1A, member 2

increases expression

ISO

Hypochlorous Acid results in increased expression of MAN1A2 mRNA

NCBI chr 2:190,636,134...190,784,975
Ensembl chr 2:190,615,094...190,784,975

G

mannosidase, alpha, class 1C, member 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MAN1C1 mRNA

NCBI chr 5:152,057,839...152,197,737
Ensembl chr 5:152,057,967...152,197,138

G

mannosidase, alpha, class 2C, member 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MAN2C1 mRNA

NCBI chr 8:66,434,480...66,445,649
Ensembl chr 8:66,434,421...66,445,648

G

mitogen activated protein kinase kinase kinase 7

increases expression

ISO

Hypochlorous Acid results in increased expression of MAP3K7 mRNA

NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012

G

mitogen activated protein kinase kinase kinase kinase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MAP4K1 mRNA

NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK1 protein
Hypochlorous Acid results in increased phosphorylation of MAPK1 protein
Roflumilast inhibits the reaction [Hypochlorous Acid results in increased phosphorylation of MAPK1 protein]

PMID:18156441 PMID:39197814

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 10

multiple interactions

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK10 protein

NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK3 protein
Hypochlorous Acid results in increased phosphorylation of MAPK3 protein
Roflumilast inhibits the reaction [Hypochlorous Acid results in increased phosphorylation of MAPK3 protein]

PMID:18156441 PMID:39197814

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 6

increases expression

ISO

Hypochlorous Acid results in increased expression of MAPK6 mRNA

NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236

G

mitogen-activated protein kinase 8

multiple interactions

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 9

multiple interactions

ISO

Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK9 protein

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228

G

membrane associated ring-CH-type finger 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MARCHF2 mRNA

NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:15,183,925...15,202,002

G

malic enzyme 1

increases expression

ISO

Hypochlorous Acid results in increased expression of ME1 mRNA

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275

G

microfibrillar-associated protein 1A

increases expression

ISO

Hypochlorous Acid results in increased expression of MFAP1 mRNA

NCBI chr 3:128,893,880...128,910,460
Ensembl chr 3:128,893,880...128,911,481

G

major facilitator superfamily domain containing 13A

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MFSD13A mRNA

NCBI chr 1:255,158,338...255,177,731
Ensembl chr 1:255,152,543...255,177,733

G

migration and invasion inhibitory protein

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MIIP mRNA

NCBI chr 5:163,575,689...163,582,739
Ensembl chr 5:163,575,437...163,582,873

G

MOB kinase activator 1A

increases expression

ISO

Hypochlorous Acid results in increased expression of MOB1A mRNA

NCBI chr 4:117,389,278...117,406,255
Ensembl chr 4:117,389,186...117,406,250

G

myeloperoxidase

multiple interactions
increases abundance
increases chemical synthesis

ISO

4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; MitoTEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; TEMPOL-H inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]

PMID:7772042 PMID:20939553 PMID:34085520 PMID:35575633

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

mitochondrial ribosomal protein L4

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MRPL4 mRNA

NCBI chr 8:27,815,771...27,821,786
Ensembl chr 8:27,815,740...27,821,780

G

methionine sulfoxide reductase B1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MSRB1 mRNA

NCBI chr10:14,269,414...14,275,140
Ensembl chr10:14,269,414...14,274,184

G

metastasis associated 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MTA1 mRNA

NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696

G

metastasis associated 1 family, member 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MTA3 mRNA

NCBI chr 6:16,619,575...16,739,732
Ensembl chr 6:16,621,998...16,739,485

G

mitochondrial amidoxime reducing component 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MTARC2 mRNA

NCBI chr13:98,894,347...98,928,754
Ensembl chr13:98,897,108...98,928,781

G

metadherin

increases expression

ISO

Hypochlorous Acid results in increased expression of MTDH mRNA

NCBI chr 7:67,192,592...67,250,819
Ensembl chr 7:67,192,393...67,249,584

G

myotubularin related protein 6

increases expression

ISO

Hypochlorous Acid results in increased expression of MTMR6 mRNA

NCBI chr15:38,596,091...38,634,023
Ensembl chr15:38,596,032...38,636,672

G

myotrophin

increases expression

ISO

Hypochlorous Acid results in increased expression of MTPN mRNA

NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924

G

mucin 16, cell surface associated

increases expression

ISO

Hypochlorous Acid results in increased expression of MUC16 mRNA

NCBI chr 8:24,440,840...24,644,494

G

mevalonate diphosphate decarboxylase

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MVD mRNA

NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366

G

myosin, heavy chain 9

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MYH9 mRNA

NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963

G

myosin IF

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MYO1F mRNA

NCBI chr 7:15,065,530...15,116,087
Ensembl chr 7:15,065,530...15,116,087

G

myosin IXb

decreases expression

ISO

Hypochlorous Acid results in decreased expression of MYO9B mRNA

NCBI chr16:17,979,374...18,064,100
Ensembl chr16:17,979,439...18,064,332

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

increases expression

ISO

Hypochlorous Acid results in increased expression of NAA15 mRNA

NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619

G

non-SMC condensin II complex, subunit H2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NCAPH2 mRNA

NCBI chr 7:122,302,550...122,319,570
Ensembl chr 7:122,300,252...122,319,569

G

NADH:ubiquinone oxidoreductase core subunit S2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NDUFS2 mRNA

NCBI chr13:86,186,867...86,203,914
Ensembl chr13:86,186,870...86,203,608

G

NADH:ubiquinone oxidoreductase core subunit S7

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NDUFS7 mRNA

NCBI chr 7:10,103,226...10,110,862
Ensembl chr 7:10,103,227...10,110,691

G

negative elongation factor complex member E

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NELFE mRNA

NCBI chr20:3,981,259...3,987,016
Ensembl chr20:3,981,261...3,986,922

G

neural EGFL like 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NELL1 mRNA

NCBI chr 1:108,845,462...109,709,858
Ensembl chr 1:108,845,462...109,709,858

G

NFE2 like bZIP transcription factor 2

multiple interactions
increases expression
affects response to substance

ISO

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]
Hypochlorous Acid results in increased expression of NFE2L2 protein
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]
NFE2L2 protein affects the susceptibility to Hypochlorous Acid

PMID:17980396 PMID:18156441

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nucleolar protein 11

increases expression

ISO

Hypochlorous Acid results in increased expression of NOL11 mRNA

NCBI chr10:92,621,482...92,641,394
Ensembl chr10:92,621,498...92,641,394

G

NAD(P)H quinone dehydrogenase 1

increases expression
affects expression

ISO

Hypochlorous Acid results in increased expression of NQO1 mRNA
Hypochlorous Acid affects the expression of NQO1 mRNA

PMID:17980396 PMID:18156441 PMID:18648578 PMID:19376150

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group D, member 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of NR1D1 mRNA

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812

G

neuropilin 1

increases expression

ISO

Hypochlorous Acid results in increased expression of NRP1 mRNA

NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702

G

nucleoporin 54

increases expression

ISO

Hypochlorous Acid results in increased expression of NUP54 mRNA

NCBI chr14:15,901,936...15,920,335
Ensembl chr14:15,901,991...15,920,334

G

OTU deubiquitinase 4

increases expression

ISO

Hypochlorous Acid results in increased expression of OTUD4 mRNA

NCBI chr19:45,141,043...45,184,136
Ensembl chr19:45,141,043...45,184,136

G

prolyl 3-hydroxylase 3

decreases expression

ISO

Hypochlorous Acid results in decreased expression of P3H3 mRNA

NCBI chr 4:159,332,514...159,348,428
Ensembl chr 4:159,332,434...159,348,004

G

protein kinase C and casein kinase substrate in neurons 3

increases expression

ISO

Hypochlorous Acid results in increased expression of PACSIN3 mRNA

NCBI chr 3:97,683,054...97,691,619
Ensembl chr 3:97,679,244...97,691,628

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 2

increases expression

ISO

Hypochlorous Acid results in increased expression of PAFAH1B2 mRNA

NCBI chr 8:55,156,778...55,208,800
Ensembl chr 8:55,156,779...55,176,836

G

PAK1 interacting protein 1

increases expression

ISO

Hypochlorous Acid results in increased expression of PAK1IP1 mRNA

NCBI chr17:23,947,978...23,959,055
Ensembl chr17:23,939,509...23,959,055

G

poly (A) polymerase alpha

increases expression

ISO

Hypochlorous Acid results in increased expression of PAPOLA mRNA

NCBI chr 6:130,446,236...130,499,371
Ensembl chr 6:130,446,797...130,499,336

G

parvin, beta

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PARVB mRNA

NCBI chr 7:117,240,238...117,325,744
Ensembl chr 7:117,240,029...117,325,748

G

protocadherin gamma subfamily C, 3

increases expression

ISO

Hypochlorous Acid results in increased expression of PCDHGC3 mRNA

NCBI chr18:29,884,245...29,919,095

G

polycomb group ring finger 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PCGF2 mRNA

NCBI chr10:83,178,926...83,191,610
Ensembl chr10:83,179,916...83,183,999

G

phosphodiesterase 4B

increases expression
multiple interactions

ISO

Hypochlorous Acid results in increased expression of PDE4B protein alternative form
Roflumilast inhibits the reaction [Hypochlorous Acid results in increased expression of PDE4B protein alternative form]

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267

G

peroxisomal biogenesis factor 6

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PEX6 mRNA

NCBI chr 9:21,755,747...21,767,939
Ensembl chr 9:21,755,751...21,767,908

G

progesterone receptor membrane component 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PGRMC2 mRNA

NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:125,996,193...126,012,090

G

phosphorylase kinase regulatory subunit alpha 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PHKA2 mRNA

NCBI chr X:37,979,629...38,102,656
Ensembl chr X:37,979,629...38,102,144

G

phosphorylase kinase catalytic subunit gamma 2

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PHKG2 mRNA

NCBI chr 1:191,614,738...191,627,615
Ensembl chr 1:191,614,865...191,627,616

G

phosphohistidine phosphatase 1

decreases expression

ISO

Hypochlorous Acid results in decreased expression of PHPT1 mRNA

NCBI chr 3:28,791,062...28,792,905

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

increases expression

ISO

Hypochlorous Acid results in increased expression of PIK3C2A mRNA

NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:180,012,248...180,117,773