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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 4.3.1.* (ammonia-lyase) inhibitor
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Accession:CHEBI:76832 term browser browse the term
Definition:An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*).
Synonyms:related_synonym: EC 4.3.1.* (ammonia-lyase) inhibitors;   EC 4.3.1.* (ammonia-lyases) inhibitor;   EC 4.3.1.* (ammonia-lyases) inhibitors;   EC 4.3.1.* inhibitor;   EC 4.3.1.* inhibitors;   ammonia-lyase inhibitor;   ammonia-lyase inhibitors



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cilastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions EXP Cilastatin inhibits the reaction [Cisplatin results in increased activity of CASP3 protein] CTD PMID:20435919 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 multiple interactions EXP Cilastatin inhibits the reaction [Cisplatin results in increased activity of CASP8 protein] CTD PMID:20435919 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G FASLG Fas ligand multiple interactions EXP Cilastatin inhibits the reaction [Cisplatin affects the localization of FASLG protein] CTD PMID:20435919 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
JBrowse link
glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of AOC1 protein] CTD PMID:36615853 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B multiple interactions EXP [Glutathione co-treated with Paraquat] results in decreased expression of CYP2B6B mRNA CTD PMID:36615853 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334
JBrowse link
G CYP3A39 cytochrome P450 3A39 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of CYP3A39 mRNA] CTD PMID:36615853
G DNAJC7 DnaJ heat shock protein family (Hsp40) member C7 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of DNAJC7 mRNA CTD PMID:36615853 NCBI chr12:20,725,937...20,756,295
Ensembl chr12:20,725,975...20,759,000
JBrowse link
G FABP2 fatty acid binding protein 2 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased activity of FABP2 protein] CTD PMID:36615853 NCBI chr 8:104,464,342...104,468,059
Ensembl chr 8:104,464,342...104,470,480
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:36615853 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GPX4 mRNA CTD PMID:36615853 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GSTA2 mRNA; Glutathione inhibits the reaction [Paraquat results in decreased expression of GSTA1 mRNA] CTD PMID:36615853 NCBI chr 7:46,538,743...46,550,781
Ensembl chr 7:46,538,032...46,548,670
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Glutathione co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA CTD PMID:36615853
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] CTD PMID:16785314 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
JBrowse link
G IFNG interferon gamma multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of IFNG mRNA] CTD PMID:36615853 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IL10 interleukin 10 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of IL10 mRNA CTD PMID:36615853 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G LOC100739508 glutathione S-transferase P-like multiple interactions EXP GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione] CTD PMID:14573868 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of NR1I3 mRNA] CTD PMID:36615853 NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,431
JBrowse link
G OCLN occludin multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in decreased expression of OCLN protein] CTD PMID:36615853 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [Glutathione co-treated with Paraquat] affects the expression of SOD2 mRNA CTD PMID:36615853 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] CTD PMID:36615853 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
L-cysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of ALB protein] CTD PMID:37999554 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
JBrowse link
G CLDN1 claudin 1 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA] CTD PMID:37999554 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLC mRNA] CTD PMID:37999554 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLM mRNA] CTD PMID:37999554 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of HMOX1 mRNA] CTD PMID:37999554
G KEAP1 kelch like ECH associated protein 1 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in increased expression of KEAP1 mRNA] CTD PMID:37999554 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
JBrowse link
G NOX1 NADPH oxidase 1 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of NOX1 mRNA] CTD PMID:37999554 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,667...82,586,532
JBrowse link
G PPP1R16A protein phosphatase 1 regulatory subunit 16A multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in increased activity of GPT protein] CTD PMID:37999554 NCBI chr 4:302,621...320,048
Ensembl chr 4:297,748...320,056
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of SDHA mRNA] CTD PMID:37999554 NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of SOD2 mRNA] CTD PMID:37999554 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TJP2 tight junction protein 2 multiple interactions EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of TJP2 mRNA] CTD PMID:37999554 NCBI chr 1:222,474,518...222,612,989
Ensembl chr 1:222,474,639...222,612,983
JBrowse link
N-acetyl-L-cysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAX protein] CTD PMID:19135140 PMID:33905761 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP [Acetylcysteine co-treated with fumonisin B1 co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with fumonisin B1] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone] results in increased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]] CTD PMID:19135140 PMID:29109043 PMID:33905761 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BMP15 bone morphogenetic protein 15 multiple interactions EXP Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of BMP15 mRNA] CTD PMID:26386189 NCBI chr  X:44,613,122...44,620,575
Ensembl chr  X:44,613,122...44,620,575
JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of and results in increased cleavage of CASP1 protein] CTD PMID:36281498 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Acetylcysteine co-treated with Zearalenone] results in decreased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]] CTD PMID:17383151 PMID:19135140 PMID:29109043 PMID:33905761 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of CASP9 protein] CTD PMID:19135140 PMID:33905761 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CAT catalase multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of CAT mRNA] CTD PMID:36281498 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions EXP Acetylcysteine inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA] CTD PMID:19265715 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]] CTD PMID:29109043 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA] CTD PMID:18086661 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] CTD PMID:18086661 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA] CTD PMID:36281498 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA] CTD PMID:36281498 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
JBrowse link
G GSDMD gasdermin D multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] CTD PMID:36281498 NCBI chr 4:995,753...1,001,964
Ensembl chr 4:995,763...1,000,271
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions EXP Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]] CTD PMID:29109043 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HSP90B1 mRNA] CTD PMID:18086661 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA] CTD PMID:18086661 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of IL1B protein] CTD PMID:36281498
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:17383151 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:17383151 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions EXP Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of MYC] CTD PMID:12712633 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Acetylcysteine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of NLRP3 protein] CTD PMID:36281498 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of INOS mRNA] CTD PMID:36281498 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of PTGS2 mRNA] CTD PMID:36281498 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G PTX3 pentraxin 3 multiple interactions EXP Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of PTX3 mRNA] CTD PMID:26386189 NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions EXP Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of PYCARD protein] CTD PMID:36281498 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
JBrowse link
G SQSTM1 sequestosome 1 multiple interactions EXP Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of SQSTM1 protein] CTD PMID:35388968 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions EXP Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of TNFAIP6 mRNA] CTD PMID:26386189 NCBI chr15:862,013...881,352
Ensembl chr15:862,015...881,461
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]] CTD PMID:29109043 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G ZP3 zona pellucida glycoprotein 3 multiple interactions EXP Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of ZP3 mRNA] CTD PMID:26386189 NCBI chr 3:9,934,760...9,944,924
Ensembl chr 3:9,934,760...9,944,941
JBrowse link
S-nitrosoglutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP 2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Wortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5164
    role 5131
      biological role 5131
        biochemical role 5054
          enzyme inhibitor 522
            EC 4.* (lyase) inhibitor 66
              EC 4.3.* (C-N lyase) inhibitor 61
                EC 4.3.1.* (ammonia-lyase) inhibitor 61
                  EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor + 0
                  EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor + 0
                  EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor + 0
                  EC 4.3.1.3 (histidine ammonia-lyase) inhibitor + 61
paths to the root