CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: EC 3.4.22.* (cysteine endopeptidase) inhibitor
Accession: CHEBI:76796
browse the term
Definition: An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*).
Synonyms: related_synonym: EC 3.4.22.* inhibitor; EC 3.4.22.* inhibitors; cysteine endopeptidase (EC 3.4.22.*) inhibitors; cysteine endopeptidase inhibitor; cysteine endopeptidase inhibitors
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD
PMID:15364539
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Apob
apolipoprotein B
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [lactacystin results in decreased expression of and results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal results in increased expression of and results in increased secretion of APOB protein
CTD
PMID:19342510 PMID:19383982
NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814
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Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Immunologic Factors results in decreased expression of BIRC5 protein]
CTD
PMID:29974605
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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Capn1
calpain 1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased expression of CAPN1 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Acrylamide results in increased expression of CAPN1 protein]
CTD
PMID:35713544 PMID:37353096
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
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Capn2
calpain 2
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased expression of CAPN2 protein]
CTD
PMID:35713544
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
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Casp3
caspase 3
increases activity multiple interactions
ISO
acetylleucyl-leucyl-norleucinal results in increased activity of CASP3 protein acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD
PMID:15618349 PMID:27481217 PMID:29111403
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp7
caspase 7
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal promotes the reaction [Immunologic Factors results in increased expression of CASP7 protein modified form]
CTD
PMID:29974605
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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Casp8
caspase 8
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD
PMID:29111403
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Cast
calpastatin
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased cleavage of CAST protein]
CTD
PMID:35713544
NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180
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Ccnb1
cyclin B1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [arsenite results in increased degradation of CCNB1 protein]
CTD
PMID:17373649
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Ccnd1
cyclin D1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [resveratrol results in increased degradation of CCND1 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]
CTD
PMID:11895924 PMID:16024653
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccnd3
cyclin D3
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND3 protein]
CTD
PMID:16024653
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
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Cdc20
cell division cycle 20
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium Chloride results in increased degradation of CDC20 protein]; acetylleucyl-leucyl-norleucinal promotes the reaction [Cadmium Chloride results in increased ubiquitination of CDC20 protein]
CTD
PMID:20054826
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
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Ctnnb1
catenin beta 1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Immunologic Factors results in decreased expression of CTNNB1 protein]
CTD
PMID:29974605
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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Dnm1l
dynamin 1-like
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal affects the reaction [Acetaminophen affects the phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased expression of and results in increased cleavage of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]
CTD
PMID:27481217 PMID:35713544
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
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Eif4e
eukaryotic translation initiation factor 4E
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein]
CTD
PMID:15878868
NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105
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Gja1
gap junction protein, alpha 1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [arsenic trioxide results in decreased expression of GJA1 mRNA]
CTD
PMID:17559834
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
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Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased activity of GPT protein]
CTD
PMID:35713544
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
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Hspa9
heat shock protein family A (Hsp70) member 9
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acrylamide results in decreased expression of HSPA9 protein]
CTD
PMID:37353096
NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398
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Il1b
interleukin 1 beta
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [IL1B protein results in increased ubiquitination of NFKBIA protein]
CTD
PMID:17291458
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Ins1
insulin 1
decreases secretion
ISO EXP
acetylleucyl-leucyl-norleucinal results in decreased secretion of INS1 protein
CTD
PMID:15618349
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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Itgam
integrin subunit alpha M
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal promotes the reaction [Tretinoin results in increased expression of ITGAM protein]
CTD
PMID:20945414
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
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Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acrylamide results in decreased expression of ITPR3 protein]
CTD
PMID:37353096
NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation
ISO
acetylleucyl-leucyl-norleucinal results in increased phosphorylation of JUN protein
CTD
PMID:15618349
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
acetylleucyl-leucyl-norleucinal results in increased phosphorylation of MAPK8 protein
CTD
PMID:15618349
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
increases expression
ISO EXP
acetylleucyl-leucyl-norleucinal results in increased expression of MAPK8IP1 protein
CTD
PMID:15618349
NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368
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Mfn2
mitofusin 2
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in decreased expression of and results in increased cleavage of MFN2 protein]
CTD
PMID:35713544
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
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Myc
MYC proto-oncogene, bHLH transcription factor
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Immunologic Factors results in decreased expression of MYC protein]
CTD
PMID:29974605
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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Nfkbia
NFKB inhibitor alpha
multiple interactions decreases degradation
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid results in increased degradation of and results in decreased expression of NFKBIA protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [IL1B protein results in increased ubiquitination of NFKBIA protein] acetylleucyl-leucyl-norleucinal results in decreased degradation of NFKBIA protein
CTD
PMID:15930313 PMID:17291458 PMID:18606398
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
CTD
PMID:29111403
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Ppp3ca
protein phosphatase 3 catalytic subunit alpha
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in increased cleavage of PPP3CA protein]
CTD
PMID:35713544
NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554
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Rad51
RAD51 recombinase
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]
CTD
PMID:21810436
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
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Rbpj
recombination signal binding protein for immunoglobulin kappa J region
increases expression
ISO
acetylleucyl-leucyl-norleucinal results in increased expression of RBPJ protein
CTD
PMID:22302987
NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307
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Scnn1g
sodium channel epithelial 1 subunit gamma
increases methylation decreases expression
ISO
acetylleucyl-leucyl-norleucinal results in increased methylation of SCNN1G promoter acetylleucyl-leucyl-norleucinal results in decreased expression of SCNN1G mRNA
CTD
PMID:15564131
NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:185,736,191...185,770,097
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Slc38a3
solute carrier family 38, member 3
multiple interactions
EXP
acetylleucyl-leucyl-norleucinal inhibits the reaction [manganese chloride results in increased degradation of SLC38A3 protein]
CTD
PMID:20737472
NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:117,202,536...117,218,630
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Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [SGA 360 results in increased degradation of and results in decreased expression of SREBF1 protein]
CTD
PMID:31225620
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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Ttn
titin
multiple interactions
EXP
acetylleucyl-leucyl-norleucinal inhibits the reaction [Doxorubicin results in increased degradation of TTN protein]
CTD
PMID:22532871
NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171
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Tymp
thymidine phosphorylase
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]]
CTD
PMID:21444628 PMID:30796972
NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
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Tyms
thymidylate synthetase
multiple interactions
ISO
acetylleucyl-leucyl-norleucinal inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]
CTD
PMID:21444628
NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097
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Capn1
calpain 1
multiple interactions
ISO
aloxistatin inhibits the reaction [CAPN1 protein results in increased degradation of and results in decreased expression of SMN2 protein alternative form]
CTD
PMID:30910806
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
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Capn7
calpain 7
multiple interactions
ISO
aloxistatin inhibits the reaction [CAPN7 protein results in increased degradation of and results in decreased expression of SMN2 protein alternative form]
CTD
PMID:30910806
NCBI chr16:6,552,048...6,588,317
Ensembl chr16:6,552,049...6,588,316
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Casp3
caspase 3
multiple interactions
ISO EXP
[aloxistatin co-treated with pepstatin] inhibits the reaction [[vistusertib co-treated with Chloroquine] results in increased activity of CASP3 protein] [Swainsonine co-treated with aloxistatin] results in increased cleavage of CASP3 protein
CTD
PMID:26853465 PMID:33186601
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp9
caspase 9
multiple interactions
ISO
aloxistatin inhibits the reaction [syringic acid analog results in increased secretion of CASP9 protein]
CTD
PMID:34523043
Ensembl chr 5:159,391,188...159,409,648
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Ctsb
cathepsin B
multiple interactions
ISO
[aloxistatin co-treated with pepstatin] results in decreased expression of CTSB protein; aloxistatin inhibits the reaction [CTSB protein results in increased degradation of and results in decreased expression of SMN2 protein alternative form]
CTD
PMID:30910806 PMID:32186374
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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Ctsd
cathepsin D
multiple interactions
ISO
[aloxistatin co-treated with pepstatin] results in decreased expression of CTSD protein
CTD
PMID:32186374
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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Ctsl
cathepsin L
multiple interactions
ISO
aloxistatin inhibits the reaction [CTSL protein results in increased degradation of and results in decreased expression of SMN2 protein alternative form]
CTD
PMID:30910806
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
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Ddx3x
DEAD-box helicase 3, X-linked
multiple interactions
ISO
aloxistatin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of DDX3X protein]
CTD
PMID:30821613
NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983
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Eif4a1
eukaryotic translation initiation factor 4A1
multiple interactions
ISO
aloxistatin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of EIF4A1 protein]
CTD
PMID:30821613
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
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Eif4h
eukaryotic translation initiation factor 4H
multiple interactions
ISO
aloxistatin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of EIF4H protein]
CTD
PMID:30821613
NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
ISO
aloxistatin inhibits the reaction [syringic acid analog results in increased secretion of GAPDH protein]
CTD
PMID:34523043
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
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Lamp2
lysosomal-associated membrane protein 2
multiple interactions
ISO
[aloxistatin co-treated with pepstatin] results in increased expression of LAMP2 protein
CTD
PMID:32186374
NCBI chr X:122,038,734...122,087,745
Ensembl chr X:121,922,187...122,087,675
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions increases lipidation
ISO
[aloxistatin co-treated with pepstatin] inhibits the reaction [Biological Factors deficiency results in increased degradation of MAP1LC3B protein modified form]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Biological Factors deficiency results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Dronabinol results in increased degradation of MAP1LC3B protein modified form]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Dronabinol results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] promotes the reaction [ABTL0812 results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] promotes the reaction [Brefeldin A results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] promotes the reaction [N-((1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl)octanamide results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] results in decreased degradation of MAP1LC3B protein modified form; aloxistatin promotes the reaction [indatraline results in increased lipidation of MAP1LC3B protein] aloxistatin results in increased lipidation of MAP1LC3B protein [aloxistatin co-treated with pepstatin] inhibits the reaction [Biological Factors deficiency results in increased degradation of MAP1LC3B protein modified form]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Biological Factors deficiency results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Dronabinol results in increased degradation of MAP1LC3B protein modified form]; [aloxistatin co-treated with pepstatin] inhibits the reaction [Dronabinol results in increased lipidation of MAP1LC3B protein]; [aloxistatin co-treated with pepstatin] results in increased expression of MAP1LC3B protein
CTD
PMID:26483381 PMID:27635674 PMID:32397857 PMID:33124469
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Sqstm1
sequestosome 1
multiple interactions increases expression
ISO
[aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein; aloxistatin promotes the reaction [indatraline results in increased expression of SQSTM1 protein]; aloxistatin promotes the reaction [Sertraline results in increased expression of SQSTM1 protein] aloxistatin results in increased expression of SQSTM1 protein [aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein; [Dronabinol co-treated with aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein; [HU 211 co-treated with aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein
CTD
PMID:26483381 PMID:32186374 PMID:32773031 PMID:33124469
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Abca1
ATP binding cassette subfamily A member 1
multiple interactions
ISO
amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]
CTD
PMID:34599948
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
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Aif1
allograft inflammatory factor 1
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein]
CTD
PMID:28185818
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein]
CTD
PMID:28185818
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]
CTD
PMID:28185818
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Casp3
caspase 3
multiple interactions
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]
CTD
PMID:28185818
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Cd36
CD36 molecule
multiple interactions
ISO
amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 mRNA]; amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]]
CTD
PMID:34599948
NCBI chr 4:18,209,088...18,302,142
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein]
CTD
PMID:28185818
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
amentoflavone results in decreased activity of CYP1B1 protein
CTD
PMID:16271822
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
G
Dct
dopachrome tautomerase
decreases expression
ISO
amentoflavone analog results in decreased expression of DCT mRNA; amentoflavone analog results in decreased expression of DCT protein
CTD
PMID:17473463
NCBI chr15:101,469,159...101,508,029
Ensembl chr15:101,469,159...101,508,029
G
Gfap
glial fibrillary acidic protein
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]
CTD
PMID:28185818
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
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Il1b
interleukin 1 beta
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]
CTD
PMID:28185818
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]
CTD
PMID:28185818
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]
CTD
PMID:28185818
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
G
Nos2
nitric oxide synthase 2
decreases expression multiple interactions
ISO
amentoflavone results in decreased expression of NOS2 protein amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]
CTD
PMID:12144868 PMID:28185818
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]; CD36 protein inhibits the reaction [amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of PPARG protein]]
CTD
PMID:34599948
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ptgds
prostaglandin D2 synthase
affects binding
ISO
amentoflavone binds to PTGDS protein
CTD
PMID:26456343
NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978
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Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression multiple interactions
ISO
amentoflavone results in decreased expression of PTGS2 mRNA; amentoflavone results in decreased expression of PTGS2 protein [amentoflavone results in decreased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone
CTD
PMID:12144868
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
ISO
amentoflavone results in decreased expression of SREBF1 mRNA
CTD
PMID:34599948
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
G
Th
tyrosine hydroxylase
multiple interactions
ISO
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]
CTD
PMID:28185818
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
G
Tyr
tyrosinase
decreases activity
ISO
amentoflavone analog results in decreased activity of TYR protein
CTD
PMID:17473463
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
decreases activity
ISO
amentoflavone results in decreased activity of UGT1A1 protein
CTD
PMID:29470958
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
G
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
decreases activity
ISO
amentoflavone results in decreased activity of UGT1A3 protein
CTD
PMID:29470958
NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a5
UDP glucuronosyltransferase family 1 member A5
decreases activity
ISO
amentoflavone results in decreased activity of UGT1A4 protein
CTD
PMID:29470958
NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
G
Ugt1a6a
UDP glucuronosyltransferase family 1 member A6a
decreases activity multiple interactions
ISO
amentoflavone results in decreased activity of UGT1A6 protein amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol]
CTD
PMID:29470958 PMID:32421801
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
decreases activity
ISO
amentoflavone results in decreased activity of UGT1A9 protein
CTD
PMID:29470958
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
decreases activity
ISO
amentoflavone results in decreased activity of UGT2B17 protein
CTD
PMID:29470958
NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression multiple interactions increases activity
ISO
baicalein results in increased expression of ABCB1 protein baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; baicalein inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]]; baicalein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] baicalein results in increased activity of ABCB1 protein
CTD
PMID:34217736
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abcc1
ATP binding cassette subfamily C member 1
decreases activity
ISO
baicalein results in decreased activity of ABCC1 protein
CTD
PMID:15670588
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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Acta2
actin alpha 2, smooth muscle
decreases expression multiple interactions
ISO
baicalein results in decreased expression of ACTA2 protein baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD
PMID:30201452
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
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Afp
alpha-fetoprotein
affects binding
EXP
baicalein binds to AFP protein
CTD
PMID:23013281 PMID:25349334
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
G
Ahr
aryl hydrocarbon receptor
multiple interactions affects response to substance increases activity increases expression
ISO
AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein]; baicalein binds to and results in increased activity of AHR protein AHR protein affects the susceptibility to baicalein baicalein results in increased activity of AHR protein baicalein results in increased expression of AHR protein
CTD
PMID:14644660 PMID:17869316 PMID:22820424
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
multiple interactions
ISO
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]
CTD
PMID:37783230
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
G
Akt1
AKT serine/threonine kinase 1
decreases phosphorylation affects binding increases phosphorylation multiple interactions
ISO
baicalein results in decreased phosphorylation of AKT1 protein baicalein binds to AKT1 protein baicalein results in increased phosphorylation of AKT1 protein baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of AKT1 mRNA]; Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [baicalein results in increased phosphorylation of AKT1 protein]
CTD
PMID:18025287 PMID:22820424 PMID:36988316 PMID:38230788
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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Alox12
arachidonate 12-lipoxygenase, 12S type
multiple interactions decreases activity
ISO
baicalein inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid] baicalein results in decreased activity of ALOX12 protein
CTD
PMID:17027136 PMID:23238474
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
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Alox15
arachidonate 15-lipoxygenase
decreases activity
ISO
baicalein results in decreased activity of ALOX15 protein
CTD
PMID:23238474
NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723
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App
amyloid beta precursor protein
multiple interactions
EXP
baicalein inhibits the reaction [APP protein binds to APP protein]
CTD
PMID:17323972
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
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Arg1
arginase 1
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in decreased expression of ARG1 protein]
CTD
PMID:38664950
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
G
Ascl3
achaete-scute family bHLH transcription factor 3
affects expression
ISO
baicalein affects the expression of ASCL3 protein
CTD
PMID:36055377
NCBI chr 1:173,190,061...173,194,302
Ensembl chr 1:173,190,228...173,192,197
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Ascl4
achaete-scute family bHLH transcription factor 4
affects expression
ISO
baicalein affects the expression of ASCL4 protein
CTD
PMID:36055377
NCBI chr 7:19,828,710...19,830,952
Ensembl chr 7:19,828,710...19,830,952
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Atf4
activating transcription factor 4
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of ATF4 protein]
CTD
PMID:33779329
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
G
Atf5
activating transcription factor 5
increases expression multiple interactions
EXP
baicalein results in increased expression of ATF5 protein [Carbon Tetrachloride co-treated with baicalein] results in increased expression of ATF5 protein
CTD
PMID:33779329
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
G
Atf6
activating transcription factor 6
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of ATF6 protein]
CTD
PMID:33779329
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
G
Atf7
activating transcription factor 7
multiple interactions
EXP
[Carbon Tetrachloride co-treated with baicalein] results in increased expression of ATF7 protein
CTD
PMID:33779329
NCBI chr 7:135,537,351...135,649,188
Ensembl chr 7:135,542,111...135,599,899
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of BAX protein modified form]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein] baicalein results in increased expression of BAX protein
CTD
PMID:20850421 PMID:21457722 PMID:37783230
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
ISO
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of BCL2 protein modified form]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein] baicalein results in decreased expression of BCL2 protein MIR3663 mRNA promotes the reaction [baicalein results in decreased expression of BCL2 protein]
CTD
PMID:20850421 PMID:33838155 PMID:37783230
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Becn1
beclin 1
multiple interactions increases expression
EXP
[Carbon Tetrachloride co-treated with baicalein] results in increased expression of BECN1 protein baicalein results in increased expression of BECN1 protein
CTD
PMID:33779329
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions decreases expression
ISO
SB 203580 inhibits the reaction [baicalein results in decreased expression of BIRC5 protein]; wortmannin promotes the reaction [baicalein results in decreased expression of BIRC5 protein]
CTD
PMID:18025287
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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Casp1
caspase 1
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]
CTD
PMID:38664950
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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Casp3
caspase 3
multiple interactions
ISO
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP3 protein modified form]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]
CTD
PMID:20850421 PMID:37783230
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp8
caspase 8
multiple interactions
ISO
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form]
CTD
PMID:20850421
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
G
Ccna1
cyclin A1
decreases expression
EXP
baicalein results in decreased expression of CCNA1 protein
CTD
PMID:11513834
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
G
Ccna2
cyclin A2
decreases expression
ISO EXP
baicalein results in decreased expression of CCNA2 protein
CTD
PMID:11513834 PMID:21457722
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
G
Ccnb1
cyclin B1
decreases expression
ISO
baicalein results in decreased expression of CCNB1 protein
CTD
PMID:18025287
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
G
Ccnd1
cyclin D1
multiple interactions decreases expression increases expression
ISO
Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of CCND1 mRNA]
CTD
PMID:19160421 PMID:21457722 PMID:22820424 PMID:24560969 PMID:36988316
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
G
Ccnd2
cyclin D2
decreases expression
EXP
baicalein results in decreased expression of CCND2 protein
CTD
PMID:11513834
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301 Ensembl chr 4:161,653,048...161,680,301
G
Ccne1
cyclin E1
decreases expression increases expression
ISO EXP
baicalein results in decreased expression of CCNE1 protein baicalein results in increased expression of CCNE1 protein
CTD
PMID:11513834 PMID:24560969
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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Cd163
CD163 molecule
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in decreased expression of CD163 mRNA]
CTD
PMID:38664950
NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146
G
Cd80
Cd80 molecule
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 mRNA]
CTD
PMID:38664950
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
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Cd86
CD86 molecule
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]
CTD
PMID:38664950
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
G
Cdk1
cyclin-dependent kinase 1
decreases phosphorylation decreases expression multiple interactions
ISO EXP
baicalein results in decreased phosphorylation of CDK1 protein baicalein results in decreased expression of CDK1 protein SB 203580 inhibits the reaction [baicalein results in decreased phosphorylation of CDK1 protein]; wortmannin promotes the reaction [baicalein results in decreased phosphorylation of CDK1 protein]
CTD
PMID:11513834 PMID:18025287
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
G
Cdk2
cyclin dependent kinase 2
decreases expression
EXP
baicalein results in decreased expression of CDK2 protein
CTD
PMID:11513834
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
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Cdk4
cyclin-dependent kinase 4
increases expression
ISO
baicalein results in increased expression of CDK4 protein
CTD
PMID:22820424
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions increases expression
ISO EXP
baicalein inhibits the reaction [Mitomycin results in increased expression of CDKN1A protein] baicalein results in increased expression of CDKN1A protein
CTD
PMID:11513834 PMID:34624459
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn2b
cyclin-dependent kinase inhibitor 2B
increases expression
EXP
baicalein results in increased expression of CDKN2B protein
CTD
PMID:11513834
NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
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Cebpa
CCAAT/enhancer binding protein alpha
decreases expression
ISO
baicalein results in decreased expression of CEBPA protein
CTD
PMID:24560969
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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Cebpb
CCAAT/enhancer binding protein beta
decreases expression
ISO
baicalein results in decreased expression of CEBPB mRNA
CTD
PMID:24560969
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
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Cebpg
CCAAT/enhancer binding protein gamma
decreases expression
ISO
baicalein results in decreased expression of CEBPG mRNA
CTD
PMID:24560969
NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:96,810,214...96,830,283
G
Cflar
CASP8 and FADD-like apoptosis regulator
multiple interactions
ISO
baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CFLAR protein]
CTD
PMID:20850421
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
G
Cftr
CF transmembrane conductance regulator
increases activity
ISO
baicalein results in increased activity of CFTR protein
CTD
PMID:15234961
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
G
Col1a1
collagen type I alpha 1 chain
multiple interactions
ISO
baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]
CTD
PMID:30201452 PMID:37783230
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
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Col1a2
collagen type I alpha 2 chain
multiple interactions
EXP
baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]
CTD
PMID:19474275
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
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Csf2
colony stimulating factor 2
decreases expression
ISO
baicalein results in decreased expression of CSF2 mRNA
CTD
PMID:10718847
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
G
Ctnnb1
catenin beta 1
decreases expression multiple interactions
ISO
baicalein results in decreased expression of CTNNB1 protein STMN1 protein inhibits the reaction [baicalein results in decreased expression of CTNNB1 protein]
CTD
PMID:38317500
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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Cycs
cytochrome c, somatic
multiple interactions
ISO
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein]
CTD
PMID:20850421
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression decreases expression multiple interactions increases chemical synthesis decreases activity
ISO
baicalein results in increased expression of CYP1A1 protein baicalein results in decreased expression of CYP1A1 mRNA [CYP1A1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein; baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; baicalein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CYP1A1 protein results in increased chemical synthesis of baicalein baicalein results in decreased activity of CYP1A1 protein
CTD
PMID:12224597 PMID:14644660 PMID:18451504 PMID:19666078 PMID:21053930 PMID:21482471 More...
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity increases chemical synthesis multiple interactions
ISO
baicalein results in decreased activity of CYP1A2 protein CYP1A2 protein results in increased chemical synthesis of baicalein [CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein
CTD
PMID:19666078 PMID:21053930 PMID:29753067
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity increases chemical synthesis multiple interactions
ISO
baicalein results in decreased activity of CYP1B1 protein CYP1B1 protein results in increased chemical synthesis of baicalein [CYP1B1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein; baicalein binds to and results in decreased activity of CYP1B1 protein; baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]
CTD
PMID:12224597 PMID:19666078 PMID:21053930 PMID:21482471
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
baicalein results in increased expression of CYP2B6 mRNA
CTD
PMID:25625231
NCBI chr 1:90,780,468...90,859,852
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases activity
ISO
baicalein results in decreased activity of CYP2C19 protein
CTD
PMID:29753067
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases activity
ISO
baicalein results in decreased activity of CYP2E1 protein
CTD
PMID:29753067
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
decreases activity
ISO
baicalein results in decreased activity of CYP3A4 protein
CTD
PMID:21053930 PMID:29753067
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Ddit3
DNA-damage inducible transcript 3
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of DDIT3 protein]
CTD
PMID:33779329
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Dgat1
diacylglycerol O-acyltransferase 1
decreases expression
ISO
baicalein results in decreased expression of DGAT1 protein
CTD
PMID:24560969
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
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Dlk1
delta like non-canonical Notch ligand 1
increases expression
ISO
baicalein results in increased expression of DLK1 mRNA
CTD
PMID:24560969
NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529
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Egf
epidermal growth factor
multiple interactions
ISO
baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalein inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein]
CTD
PMID:25625231
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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Egfr
epidermal growth factor receptor
multiple interactions affects binding decreases phosphorylation
ISO
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of EGFR mRNA]; baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of EGFR protein] baicalein binds to EGFR protein
CTD
PMID:25625231 PMID:33838155 PMID:38230788
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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Egr2
early growth response 2
decreases expression
ISO
baicalein results in decreased expression of EGR2 mRNA
CTD
PMID:24560969
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of EIF2AK3 protein]
CTD
PMID:33779329
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
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Elk1
ETS transcription factor ELK1
multiple interactions
ISO
baicalein inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein]
CTD
PMID:25625231
NCBI chr X:3,692,367...3,709,252
Ensembl chr X:3,693,293...3,709,249
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Epo
erythropoietin
increases expression
ISO
baicalein results in increased expression of EPO mRNA
CTD
PMID:37348668
NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
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Erbb2
erb-b2 receptor tyrosine kinase 2
multiple interactions decreases expression
ISO
baicalein results in decreased expression of and results in decreased phosphorylation of ERBB2 protein baicalein results in decreased expression of ERBB2 mRNA
CTD
PMID:36988316
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
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Ern1
endoplasmic reticulum to nucleus signaling 1
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of ERN1 protein]
CTD
PMID:33779329
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
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Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
baicalein binds to ESR1 protein baicalein inhibits the reaction [Cholesterol, LDL analog results in decreased expression of ESR1 mRNA]
CTD
PMID:38230788
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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Fabp4
fatty acid binding protein 4
decreases expression
ISO
baicalein results in decreased expression of FABP4 protein
CTD
PMID:24560969
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
G
Fasn
fatty acid synthase
decreases expression
ISO
baicalein results in decreased expression of FASN protein
CTD
PMID:24560969
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
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Fn1
fibronectin 1
multiple interactions
ISO
baicalein inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]
CTD
PMID:30201452
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
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Glb1
galactosidase, beta 1
multiple interactions
ISO
baicalein inhibits the reaction [Mitomycin results in increased activity of GLB1 protein]
CTD
PMID:34624459
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
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Gli1
GLI family zinc finger 1
decreases expression
ISO
baicalein results in decreased expression of GLI1 mRNA; baicalein results in decreased expression of GLI1 protein
CTD
PMID:20395211
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
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Gpat3
glycerol-3-phosphate acyltransferase 3
decreases expression
ISO
baicalein results in decreased expression of GPAT3 protein
CTD
PMID:24560969
NCBI chr14:9,018,762...9,072,552
G
Gpx4
glutathione peroxidase 4
affects expression multiple interactions
ISO
baicalein affects the expression of GPX4 protein baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]]
CTD
PMID:36055377 PMID:37354967
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Gsdmd
gasdermin D
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of GSDMD protein]
CTD
PMID:38664950
NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
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Gsk3b
glycogen synthase kinase 3 beta
decreases phosphorylation multiple interactions
ISO
baicalein results in decreased phosphorylation of GSK3B protein baicalein inhibits the reaction [Mitomycin results in increased phosphorylation of GSK3B protein]
CTD
PMID:22820424 PMID:34624459 PMID:36988316
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
G
Hes1
hes family bHLH transcription factor 1
multiple interactions increases expression
ISO
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HES1 mRNA]
CTD
PMID:19160421
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
G
Hey1
hes-related family bHLH transcription factor with YRPW motif 1
multiple interactions increases expression
ISO
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HEY1 mRNA]
CTD
PMID:19160421
NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624
G
Hey2
hes-related family bHLH transcription factor with YRPW motif 2
multiple interactions increases expression
ISO
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HEY2 mRNA]
CTD
PMID:19160421
NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions increases expression
ISO
baicalein results in decreased degradation of and results in increased expression of HIF1A protein modified form baicalein results in increased expression of HIF1A mRNA; baicalein results in increased expression of HIF1A protein
CTD
PMID:37348668
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
baicalein results in increased expression of HMOX1 mRNA; baicalein results in increased expression of HMOX1 protein baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]; baicalein inhibits the reaction [Polymyxin B results in increased expression of HMOX1 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]] Hemin promotes the reaction [baicalein results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]
CTD
PMID:14563492 PMID:37354967
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
multiple interactions increases activity
ISO
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [baicalein results in increased activity of HSD11B2 protein]
CTD
PMID:18032417
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of HSPA5 protein]
CTD
PMID:33779329
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Igf1
insulin-like growth factor 1
multiple interactions
ISO
baicalein inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]
CTD
PMID:17458902
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
G
Il10
interleukin 10
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in decreased expression of IL10 mRNA]
CTD
PMID:38664950
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
G
Il1b
interleukin 1 beta
multiple interactions
ISO
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B protein]; baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of IL1B protein]
CTD
PMID:22369883 PMID:38230788 PMID:38664950
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il6
interleukin 6
multiple interactions
ISO
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of IL6 protein]
CTD
PMID:38230788
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Ins2
insulin 2
multiple interactions increases secretion
ISO
baicalein promotes the reaction [Glucose results in increased secretion of INS protein] baicalein results in increased secretion of INS protein
CTD
PMID:17192482
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions affects binding
ISO
baicalein inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of JUN mRNA] baicalein binds to JUN protein
CTD
PMID:17458902 PMID:38230788
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Klf2
KLF transcription factor 2
increases expression
ISO
baicalein results in increased expression of KLF2 mRNA
CTD
PMID:24560969
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768
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Klf5
KLF transcription factor 5
decreases expression
ISO
baicalein results in decreased expression of KLF5 mRNA
CTD
PMID:24560969
NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262
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Lpin1
lipin 1
decreases expression
ISO
baicalein results in decreased expression of LPIN1 protein
CTD
PMID:24560969
NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991
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Mapk1
mitogen activated protein kinase 1
multiple interactions affects binding decreases phosphorylation
ISO
baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of MAPK1 mRNA]; baicalein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of MAPK1 protein] baicalein binds to MAPK1 protein baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK1 protein]
CTD
PMID:10718847 PMID:20850421 PMID:31811862 PMID:33838155 PMID:38230788
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk3
mitogen activated protein kinase 3
multiple interactions decreases phosphorylation
ISO
baicalein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of MAPK3 protein] baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:10718847 PMID:20850421 PMID:31811862 PMID:33838155
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
baicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein
CTD
PMID:10718847
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mir1224
microRNA 1224
increases expression
ISO
baicalein results in increased expression of MIR1224 mRNA
CTD
PMID:33838155
NCBI chr11:93,811,291...93,811,375
G
Mir21
microRNA 21
multiple interactions
ISO
baicalein inhibits the reaction [TGFB1 protein results in increased expression of MIR21 mRNA]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD
PMID:30201452
NCBI chr10:71,902,600...71,902,691
G
Mir322
microRNA 322
increases expression
ISO
baicalein results in increased expression of MIR424 mRNA
CTD
PMID:33838155
NCBI chr X:137,726,147...137,726,241
G
Mmp2
matrix metallopeptidase 2
decreases activity multiple interactions
ISO
baicalein results in decreased activity of MMP2 protein baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP2 mRNA]
CTD
PMID:21803068 PMID:22369883 PMID:36988316
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
G
Mmp9
matrix metallopeptidase 9
multiple interactions decreases expression decreases activity
ISO
baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; STMN1 protein inhibits the reaction [baicalein results in decreased expression of MMP9 protein] baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP9 mRNA] baicalein results in decreased activity of MMP9 protein
CTD
PMID:19804834 PMID:21803068 PMID:22369883 PMID:38317500
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Mpo
myeloperoxidase
multiple interactions
ISO
baicalein inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]
CTD
PMID:27780710
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Mrc1
mannose receptor, C type 1
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in decreased expression of MRC1 protein]
CTD
PMID:38664950
NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410
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Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
baicalein results in decreased phosphorylation of and results in decreased activity of MTOR protein
CTD
PMID:24560969
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
G
Nat1
N-acetyltransferase 1
decreases expression
ISO
baicalein results in decreased expression of NAT1 mRNA; baicalein results in decreased expression of NAT1 protein
CTD
PMID:15796204
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
G
Nfkb1
nuclear factor kappa B subunit 1
decreases localization
ISO
baicalein results in decreased localization of NFKB1 protein
CTD
PMID:21803068
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
G
Nfkbia
NFKB inhibitor alpha
multiple interactions decreases phosphorylation
ISO
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of NFKBIA protein] baicalein results in decreased phosphorylation of NFKBIA protein
CTD
PMID:20850421
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
G
Nfkbib
NFKB inhibitor beta
decreases phosphorylation
ISO
baicalein results in decreased phosphorylation of NFKBIB protein
CTD
PMID:21803068
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
G
Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
ISO
baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]
CTD
PMID:38664950
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
G
Nos2
nitric oxide synthase 2
multiple interactions decreases expression
ISO
baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]; baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Hemin promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; HMOX1 protein promotes the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]; tin protoporphyrin IX inhibits the reaction [baicalein inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]] baicalein results in decreased expression of NOS2 protein
CTD
PMID:14563492 PMID:20850421 PMID:22369883 PMID:38664950
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Notch1
notch receptor 1
increases activity increases expression
ISO
baicalein results in increased activity of NOTCH1 protein baicalein results in increased expression of NOTCH1 mRNA
CTD
PMID:19160421
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects localization
ISO
baicalein affects the localization of NR1I3 protein
CTD
PMID:25625231
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
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Pcna
proliferating cell nuclear antigen
multiple interactions decreases expression
ISO
STMN1 protein inhibits the reaction [baicalein results in decreased expression of PCNA protein]
CTD
PMID:38317500
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
G
Pik3c3
phosphatidylinositol 3-kinase, catalytic subunit type 3
multiple interactions
EXP
[Carbon Tetrachloride co-treated with baicalein] results in increased expression of PIK3C3 protein
CTD
PMID:33779329
NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
affects binding multiple interactions
ISO
baicalein binds to PIK3CA protein baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of PIK3CA mRNA]
CTD
PMID:38230788
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
G
Pkm
pyruvate kinase M1/2
increases activity
ISO
baicalein results in increased activity of PKM protein
CTD
PMID:25388478
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
G
Pla2g2a
phospholipase A2 group IIA
multiple interactions
ISO
baicalein inhibits the reaction [PLA2G2A protein results in increased expression of PTGS2 protein]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK1 protein]; baicalein inhibits the reaction [PLA2G2A protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:31811862
NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
G
Plau
plasminogen activator, urokinase
decreases activity
ISO
baicalein results in decreased activity of PLAU protein
CTD
PMID:21803068
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
ISO
baicalein inhibits the reaction [Fenretinide results in increased expression of PMAIP1 mRNA]
CTD
PMID:17216584
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases expression
ISO
baicalein results in decreased expression of PPARG protein
CTD
PMID:24560969
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Prkca
protein kinase C, alpha
decreases phosphorylation
ISO
baicalein results in decreased phosphorylation of PRKCA protein
CTD
PMID:21803068
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; baicalein inhibits the reaction [PLA2G2A protein results in increased expression of PTGS2 protein]; baicalein inhibits the reaction [Polymyxin B results in increased expression of PTGS2 protein]
CTD
PMID:19804834 PMID:22369883 PMID:31811862 PMID:37354967
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Pygb
glycogen phosphorylase B
decreases activity
ISO
baicalein results in decreased activity of PYGB protein
CTD
PMID:37277066
NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961
G
Pygl
glycogen phosphorylase L
decreases activity
ISO
baicalein results in decreased activity of PYGL protein
CTD
PMID:37277066
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
G
Rb1
RB transcriptional corepressor 1
multiple interactions decreases phosphorylation
ISO
AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein]; Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein]
CTD
PMID:22820424
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions decreases phosphorylation affects localization decreases localization
ISO
baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of RELA protein]; baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of RELA protein] baicalein results in decreased phosphorylation of RELA protein MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of RELA protein]; NKILA mRNA promotes the reaction [baicalein affects the localization of RELA protein] baicalein results in decreased localization of RELA protein
CTD
PMID:20850421 PMID:21803068 PMID:22369883 PMID:29481769 PMID:33838155
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions
ISO
baicalein results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein
CTD
PMID:24560969
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
G
Sh3gl1
SH3 domain containing GRB2 like 1, endophilin A2
decreases expression multiple interactions
ISO
baicalein results in decreased expression of SH3GL1 mRNA; baicalein results in decreased expression of SH3GL1 protein MIR3663 mRNA promotes the reaction [baicalein results in decreased expression of SH3GL1 protein]
CTD
PMID:33838155
NCBI chr 9:929,459...956,922
Ensembl chr 9:928,563...956,890
G
Sirt1
sirtuin 1
multiple interactions
ISO
baicalein inhibits the reaction [Polymyxin B results in decreased expression of SIRT1 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of GPX4 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of HMOX1 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]]
CTD
PMID:37354967
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
G
Slc22a6
solute carrier family 22 member 6
decreases activity
ISO
baicalein results in decreased activity of SLC22A6 protein
CTD
PMID:32159797
NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311
G
Slc7a11
solute carrier family 7 member 11
multiple interactions
ISO
baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in decreased expression of SLC7A11 protein]]
CTD
PMID:37354967
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
G
Snca
synuclein alpha
multiple interactions
ISO
baicalein inhibits the reaction [SNCA protein binds to SNCA protein] baicalein inhibits the reaction [Rotenone promotes the reaction [SNCA protein binds to SNCA protein]]; baicalein inhibits the reaction [Rotenone results in increased expression of SNCA protein]
CTD
PMID:27425033
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
G
Spry1
sprouty RTK signaling antagonist 1
multiple interactions
ISO
baicalein inhibits the reaction [TGFB1 protein results in decreased expression of SPRY1 protein]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD
PMID:30201452
NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:122,484,355...122,492,956
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
affects binding multiple interactions
ISO
baicalein binds to SRC protein baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of SRC mRNA]
CTD
PMID:38230788
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
G
Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
ISO
baicalein results in decreased expression of SREBF1 protein
CTD
PMID:24560969
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
G
Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:30201452
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
G
Stmn1
stathmin 1
decreases expression multiple interactions
ISO
baicalein results in decreased expression of STMN1 protein STMN1 protein inhibits the reaction [baicalein results in decreased expression of CTNNB1 protein]; STMN1 protein inhibits the reaction [baicalein results in decreased expression of MMP9 protein]; STMN1 protein inhibits the reaction [baicalein results in decreased expression of PCNA protein]; STMN1 protein inhibits the reaction [baicalein results in decreased expression of WNT3A protein]
CTD
PMID:38317500
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
EXP ISO
baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]] baicalein inhibits the reaction [TGFB1 protein results in decreased expression of SPRY1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; baicalein inhibits the reaction [TGFB1 protein results in increased expression of MIR21 mRNA]; baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein]; MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
CTD
PMID:19474275 PMID:30201452 PMID:37783230
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
G
Th
tyrosine hydroxylase
multiple interactions
ISO
baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein]
CTD
PMID:27425033
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
G
Tnf
tumor necrosis factor
decreases expression multiple interactions
ISO
baicalein results in decreased expression of TNF protein baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of TNF protein] baicalein inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF protein]; baicalein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD
PMID:20850421 PMID:22369883 PMID:38230788 PMID:38664950
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Tp53
tumor protein p53
increases expression affects binding multiple interactions
ISO EXP
baicalein results in increased expression of TP53 protein baicalein binds to TP53 protein baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of TP53 mRNA]; baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]; SIRT1 protein promotes the reaction [baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]]
CTD
PMID:11513834 PMID:21457722 PMID:37354967 PMID:38230788
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
G
Vegfa
vascular endothelial growth factor A
decreases expression
ISO
baicalein results in decreased expression of VEGFA protein
CTD
PMID:16638750 PMID:36988316
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
G
Wnt3a
Wnt family member 3A
decreases expression multiple interactions
ISO
baicalein results in decreased expression of WNT3A protein STMN1 protein inhibits the reaction [baicalein results in decreased expression of WNT3A protein]
CTD
PMID:38317500
NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919
G
Xbp1
X-box binding protein 1
multiple interactions
EXP
baicalein inhibits the reaction [Carbon Tetrachloride results in increased expression of XBP1 protein]
CTD
PMID:33779329
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
G
Xdh
xanthine dehydrogenase
multiple interactions
ISO
baicalein inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein]
CTD
PMID:34044073
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
G
Xiap
X-linked inhibitor of apoptosis
multiple interactions
ISO
baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of XIAP protein]
CTD
PMID:20850421
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
cryptolepine results in increased expression of BAX mRNA; cryptolepine results in increased expression of BAX protein
CTD
PMID:16120219
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
cryptolepine results in decreased expression of BIRC3 mRNA
CTD
PMID:16120219
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
G
Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
cryptolepine results in decreased expression of BUB1 mRNA
CTD
PMID:16120219
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
G
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
decreases expression
ISO
cryptolepine results in decreased expression of BUB1B mRNA
CTD
PMID:16120219
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
G
Ccna2
cyclin A2
decreases expression
ISO
cryptolepine results in decreased expression of CCNA2 mRNA; cryptolepine results in decreased expression of CCNA2 protein
CTD
PMID:16120219
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
G
Ccnb1
cyclin B1
decreases expression
ISO
cryptolepine results in decreased expression of CCNB1 mRNA; cryptolepine results in decreased expression of CCNB1 protein
CTD
PMID:16120219
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
G
Ccnd1
cyclin D1
increases expression
ISO
cryptolepine results in increased expression of CCND1 mRNA
CTD
PMID:16120219
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
G
Cdc25c
cell division cycle 25C
decreases expression
ISO
cryptolepine results in decreased expression of CDC25C mRNA
CTD
PMID:16120219
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
G
Cdc34
cell division cycle 34, ubiquitin conjugating enzyme
decreases expression
ISO
cryptolepine results in decreased expression of CDC34 mRNA
CTD
PMID:16120219
NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,668,210...10,674,526
G
Cdc45
cell division cycle 45
decreases expression
ISO
cryptolepine results in decreased expression of CDC45 mRNA
CTD
PMID:16120219
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
G
Cdc6
cell division cycle 6
decreases expression
ISO
cryptolepine results in decreased expression of CDC6 mRNA
CTD
PMID:16120219
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
cryptolepine results in increased expression of CDKN1A mRNA; cryptolepine results in increased expression of CDKN1A protein
CTD
PMID:16120219
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
G
Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
ISO
cryptolepine results in decreased expression of CDKN3 mRNA
CTD
PMID:16120219
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
G
Cenpf
centromere protein F
decreases expression
ISO
cryptolepine results in decreased expression of CENPF mRNA
CTD
PMID:16120219
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
G
Gdf15
growth differentiation factor 15
increases expression
ISO
cryptolepine results in increased expression of GDF15 mRNA
CTD
PMID:16120219
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
G
Mcm2
minichromosome maintenance complex component 2
decreases expression
ISO
cryptolepine results in decreased expression of MCM2 mRNA
CTD
PMID:16120219
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
G
Mcm6
minichromosome maintenance complex component 6
decreases expression
ISO
cryptolepine results in decreased expression of MCM6 mRNA
CTD
PMID:16120219
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
G
Mcm7
minichromosome maintenance complex component 7
decreases expression
ISO
cryptolepine results in decreased expression of MCM7 mRNA
CTD
PMID:16120219
NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
G
Mcm8
minichromosome maintenance 8 homologous recombination repair factor
decreases expression
ISO
cryptolepine results in decreased expression of MCM8 mRNA
CTD
PMID:16120219
NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891
G
Mdm2
MDM2 proto-oncogene
increases expression
ISO
cryptolepine results in increased expression of MDM2 mRNA; cryptolepine results in increased expression of MDM2 protein
CTD
PMID:16120219
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
G
Myt1
myelin transcription factor 1
decreases expression
ISO
cryptolepine results in decreased expression of MYT1 mRNA
CTD
PMID:16120219
NCBI chr 3:189,263,569...189,327,844
Ensembl chr 3:189,263,467...189,327,844
G
Nek2
NIMA-related kinase 2
decreases expression
ISO
cryptolepine results in decreased expression of NEK2 mRNA
CTD
PMID:16120219
NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056
G
Tp53
tumor protein p53
increases expression increases activity
ISO
cryptolepine results in increased expression of TP53 protein cryptolepine results in increased activity of TP53 protein
CTD
PMID:16120219
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
G
Ttk
Ttk protein kinase
decreases expression
ISO
cryptolepine results in decreased expression of TTK mRNA
CTD
PMID:16120219
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
G
Acta2
actin alpha 2, smooth muscle
multiple interactions
ISO
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
CTD
PMID:16757516
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
G
Adam9
ADAM metallopeptidase domain 9
multiple interactions
ISO
ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein]
CTD
PMID:17018608
NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646
G
Afp
alpha-fetoprotein
multiple interactions
EXP
ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA]
CTD
PMID:11133813
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
G
Alad
aminolevulinate dehydratase
multiple interactions decreases activity
EXP ISO
Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein] ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]
CTD
PMID:14630126 PMID:17624921 PMID:23933410
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
G
Alox5
arachidonate 5-lipoxygenase
decreases activity
ISO
ebselen results in decreased activity of ALOX5 protein
CTD
PMID:7590103
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
CTD
PMID:30558456
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
CTD
PMID:30558456
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Casp3
caspase 3
multiple interactions increases activity
ISO EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein] ebselen results in increased activity of CASP3 protein ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
CTD
PMID:21300091 PMID:23649643 PMID:25068500 PMID:30558456
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Casp9
caspase 9
multiple interactions
ISO EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein] ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]
CTD
PMID:18629305 PMID:23649643
Ensembl chr 5:159,391,188...159,409,648
G
Cat
catalase
increases activity multiple interactions
EXP
ebselen results in increased activity of CAT protein ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD
PMID:27282967 PMID:30558456
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
G
Cox4i1
cytochrome c oxidase subunit 4i1
increases expression
ISO
ebselen results in increased expression of COX4I1 protein
CTD
PMID:27385396
NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
G
Cs
citrate synthase
multiple interactions
ISO EXP
ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] ebselen inhibits the reaction [Cisplatin results in decreased activity of CS protein]
CTD
PMID:27385396 PMID:32860823
NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
EXP
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]
CTD
PMID:11903743
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
G
Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
increases phosphorylation
EXP
ebselen results in increased phosphorylation of EIF2S1 protein
CTD
PMID:27282967
NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
G
Ephx2
epoxide hydrolase 2
multiple interactions
ISO
ebselen binds to and results in decreased activity of EPHX2 protein
CTD
PMID:23219563
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
G
Fmr1
fragile X messenger ribonucleoprotein 1
multiple interactions
ISO
ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]
CTD
PMID:27385396
NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein]
CTD
PMID:14572605
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
multiple interactions
EXP
ebselen inhibits the reaction [Cisplatin results in increased activity of G6PC1 protein]
CTD
PMID:32860823
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
G
Gck
glucokinase
multiple interactions
ISO
[ebselen co-treated with Glucose] results in increased activity of GCK protein
CTD
PMID:23795780
NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949
G
Gfap
glial fibrillary acidic protein
increases phosphorylation
EXP
ebselen results in increased phosphorylation of GFAP protein
CTD
PMID:27282967
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
G
Gja1
gap junction protein, alpha 1
multiple interactions
EXP
ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein]
CTD
PMID:12958040
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
G
Gpx1
glutathione peroxidase 1
multiple interactions
ISO
ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]] ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]
CTD
PMID:23795780 PMID:28383113
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gsr
glutathione-disulfide reductase
increases activity multiple interactions
EXP
ebselen results in increased activity of GSR protein ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD
PMID:27282967 PMID:30558456
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
G
Gsta1
glutathione S-transferase alpha 1
multiple interactions
EXP
ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]
CTD
PMID:8147899
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
G
Gsta3
glutathione S-transferase alpha 3
multiple interactions
EXP
ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein
CTD
PMID:8147899
NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654
G
Gstm1
glutathione S-transferase mu 1
multiple interactions
EXP
ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]
CTD
PMID:8147899
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
G
Gstm2
glutathione S-transferase mu 2
multiple interactions
EXP
ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]
CTD
PMID:8147899
NCBI chr 2:198,312,179...198,316,962
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
ebselen binds to and results in decreased activity of GSTP1 protein
CTD
PMID:8147899
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]
CTD
PMID:19374849
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
G
Hmox1
heme oxygenase 1
multiple interactions
EXP
[ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein
CTD
PMID:16959961
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hpgds
hematopoietic prostaglandin D synthase
increases expression
ISO
ebselen results in increased expression of HPGDS mRNA
CTD
PMID:21669866
NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501
G
Hsf1
heat shock transcription factor 1
increases activity
ISO
ebselen results in increased activity of HSF1 protein
CTD
PMID:34170685
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
G
Ifng
interferon gamma
multiple interactions
ISO
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
CTD
PMID:12794164
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Il6
interleukin 6
multiple interactions
EXP
ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]
CTD
PMID:30558456
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Ins1
insulin 1
multiple interactions
ISO
ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; ebselen promotes the reaction [Glucose results in increased secretion of INS1 protein]
CTD
PMID:23795780
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
G
Mapk1
mitogen activated protein kinase 1
multiple interactions increases activity increases phosphorylation
ISO EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] ebselen results in increased activity of MAPK1 protein ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein] ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein
CTD
PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk3
mitogen activated protein kinase 3
multiple interactions increases activity increases phosphorylation
ISO EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] ebselen results in increased activity of MAPK3 protein ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:20495008 PMID:21300091 PMID:21960664 PMID:22001386 PMID:27282967
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
G
Mapk9
mitogen-activated protein kinase 9
increases phosphorylation
EXP
ebselen results in increased phosphorylation of MAPK9 protein
CTD
PMID:27282967
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
G
Mmp13
matrix metallopeptidase 13
multiple interactions
EXP
ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA]
CTD
PMID:11903743
NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
G
Ngf
nerve growth factor
multiple interactions
ISO
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:20495008
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
G
Nos2
nitric oxide synthase 2
multiple interactions decreases activity
ISO EXP
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] ebselen results in decreased activity of NOS2 protein
CTD
PMID:7590103 PMID:12794164
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
G
Nqo1
NAD(P)H quinone dehydrogenase 1
decreases activity
EXP
ebselen results in decreased activity of NQO1 protein
CTD
PMID:7590103
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
G
Pdx1
pancreatic and duodenal homeobox 1
multiple interactions
ISO
[ebselen co-treated with Glucose] results in increased expression of PDX1 protein
CTD
PMID:23795780
NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156
G
Phospho1
phosphoethanolamine/phosphocholine phosphatase 1
decreases activity
ISO
ebselen results in decreased activity of PHOSPHO1 protein
CTD
PMID:17227223
NCBI chr10:81,258,810...81,266,345
Ensembl chr10:81,257,427...81,268,481
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein]
CTD
PMID:14572605
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Slc11a2
solute carrier family 11 member 2
multiple interactions
ISO
ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]
CTD
PMID:16984886
NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941
G
Slc2a2
solute carrier family 2 member 2
multiple interactions
ISO EXP
[ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein ebselen inhibits the reaction [Cisplatin results in increased expression of SLC2A2 protein]
CTD
PMID:23795780 PMID:32860823
NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467
G
Smad3
SMAD family member 3
multiple interactions
ISO
ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD
PMID:21131394
NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
G
Sod1
superoxide dismutase 1
decreases response to substance multiple interactions
ISO
ebselen results in decreased susceptibility to SOD1 protein mutant form ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD
PMID:16702190 PMID:23795780
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sod2
superoxide dismutase 2
multiple interactions
EXP
ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:20495008
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
G
Tat
tyrosine aminotransferase
multiple interactions
EXP
ebselen inhibits the reaction [Cisplatin results in increased activity of TAT protein]
CTD
PMID:32860823
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
EXP ISO
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD
PMID:11903743 PMID:16757516 PMID:21131394
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
G
Timp1
TIMP metallopeptidase inhibitor 1
multiple interactions
EXP
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]
CTD
PMID:11903743
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
G
Tnf
tumor necrosis factor
multiple interactions
EXP
ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
CTD
PMID:30558456
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Txnrd1
thioredoxin reductase 1
multiple interactions
ISO
ebselen results in increased expression of and results in increased activity of TXNRD1 protein
CTD
PMID:28383113
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
G
Ucp2
uncoupling protein 2
multiple interactions
ISO
[ebselen co-treated with Glucose] results in decreased expression of UCP2 protein
CTD
PMID:23795780
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
G
Xbp1
X-box binding protein 1
increases phosphorylation
EXP
ebselen results in increased phosphorylation of XBP1 protein
CTD
PMID:27282967
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
G
Xpa
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
ebselen inhibits the reaction [Zinc binds to XPA protein]
CTD
PMID:15265038
NCBI chr 5:65,227,281...65,275,784
Ensembl chr 5:65,227,281...65,272,425
G
Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
geldanamycin inhibits the reaction [TNF protein results in increased expression of ABCB1 mRNA]
CTD
PMID:37586545
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
G
Acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
increases expression
ISO
geldanamycin results in increased expression of ACAP2 mRNA
CTD
PMID:26705709
NCBI chr11:83,043,442...83,159,105
Ensembl chr11:83,043,511...83,159,107
G
Actr2
actin related protein 2
increases expression
ISO
geldanamycin results in increased expression of ACTR2 mRNA
CTD
PMID:26705709
NCBI chr14:98,500,119...98,535,092
Ensembl chr14:98,500,138...98,541,998
G
Aff3
ALF transcription elongation factor 3
increases expression
ISO
geldanamycin results in increased expression of AFF3 mRNA
CTD
PMID:26705709
NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:47,894,903...48,353,000
G
Aff4
ALF transcription elongation factor 4
increases expression
ISO
geldanamycin results in increased expression of AFF4 mRNA
CTD
PMID:26705709
NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580
G
Agfg1
ArfGAP with FG repeats 1
increases expression
ISO
geldanamycin results in increased expression of AGFG1 mRNA
CTD
PMID:26705709
NCBI chr 9:91,572,962...91,630,688
Ensembl chr 9:91,573,157...91,626,910
G
Ahr
aryl hydrocarbon receptor
increases localization decreases expression increases degradation multiple interactions
ISO
geldanamycin results in increased localization of AHR protein geldanamycin results in decreased expression of AHR protein geldanamycin results in increased degradation of AHR protein; geldanamycin results in increased degradation of AHR protein mutant form benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in decreased expression of AHR protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein]]; geldanamycin results in increased localization of and results in increased degradation of AHR protein; lactacystin inhibits the reaction [geldanamycin results in increased degradation of AHR protein]
CTD
PMID:9664232 PMID:12237327 PMID:12606767 PMID:16226227 PMID:20057149 PMID:27105554 More...
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
G
Akt1
AKT serine/threonine kinase 1
multiple interactions decreases phosphorylation decreases expression
ISO
[geldanamycin co-treated with Bortezomib] results in decreased expression of AKT1 protein; geldanamycin inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of AKT1 protein]; geldanamycin results in decreased expression of and results in decreased phosphorylation of AKT1 protein geldanamycin results in decreased phosphorylation of AKT1 protein geldanamycin results in decreased expression of AKT1 protein
CTD
PMID:15781649 PMID:17293044 PMID:19167484 PMID:24211270 PMID:24450340 PMID:29993192 More...
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
G
Akt3
AKT serine/threonine kinase 3
increases expression
ISO
geldanamycin results in increased expression of AKT3 mRNA
CTD
PMID:26705709
NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020
G
Amotl1
angiomotin-like 1
increases expression
ISO
geldanamycin results in increased expression of AMOTL1 mRNA
CTD
PMID:26705709
NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869
G
Angpt1
angiopoietin 1
increases expression
ISO
geldanamycin results in increased expression of ANGPT1 mRNA
CTD
PMID:26705709
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
G
Angptl1
angiopoietin-like 1
decreases expression
ISO
geldanamycin results in decreased expression of ANGPTL1 mRNA
CTD
PMID:26705709
NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818
G
Ankrd1
ankyrin repeat domain 1
increases expression
ISO
geldanamycin results in increased expression of ANKRD1 mRNA
CTD
PMID:26705709
NCBI chr 1:243,228,460...243,237,014
Ensembl chr 1:243,228,448...243,263,751
G
Ap5m1
adaptor related protein complex 5 subunit mu 1
increases expression
ISO
geldanamycin results in increased expression of AP5M1 mRNA
CTD
PMID:26705709
NCBI chr15:24,835,122...24,864,854
Ensembl chr15:24,835,100...24,862,606
G
Apela
apelin receptor early endogenous ligand
increases expression
ISO
geldanamycin results in increased expression of APELA mRNA
CTD
PMID:26705709
NCBI chr16:29,460,855...29,469,962
Ensembl chr16:29,460,812...29,469,955
G
Appl2
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
increases expression
ISO
geldanamycin results in increased expression of APPL2 mRNA
CTD
PMID:26705709
NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:22,022,963...22,072,385
G
Arb2a
ARB2 cotranscriptional regulator A
increases expression
ISO
geldanamycin results in increased expression of ARB2A mRNA
CTD
PMID:26705709
NCBI chr 2:9,289,694...9,753,991
Ensembl chr 2:9,289,699...9,753,989
G
Arfip1
ARF interacting protein 1
increases expression
ISO
geldanamycin results in increased expression of ARFIP1 mRNA
CTD
PMID:26705709
NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280
G
Aspm
assembly factor for spindle microtubules
increases expression
ISO
geldanamycin results in increased expression of ASPM mRNA
CTD
PMID:26705709
NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
G
Atp11b
ATPase phospholipid transporting 11B (putative)
increases expression
ISO
geldanamycin results in increased expression of ATP11B mRNA
CTD
PMID:26705709
NCBI chr 2:120,513,535...120,619,249
Ensembl chr 2:120,513,552...120,619,249
G
Atp11c
ATPase phospholipid transporting 11C
increases expression
ISO
geldanamycin results in increased expression of ATP11C mRNA
CTD
PMID:26705709
NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432
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Atp13a3
ATPase 13A3
increases expression
ISO
geldanamycin results in increased expression of ATP13A3 mRNA
CTD
PMID:26705709
NCBI chr11:83,860,725...83,946,899
Ensembl chr11:83,870,218...83,944,662
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Atp13a5
ATPase 13A5
increases expression
ISO
geldanamycin results in increased expression of ATP13A5 mRNA
CTD
PMID:26705709
NCBI chr11:84,881,196...85,020,597
Ensembl chr11:84,881,230...85,020,593
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Atrx
ATRX, chromatin remodeler
increases expression
ISO
geldanamycin results in increased expression of ATRX mRNA
CTD
PMID:26705709
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880
G
Atxn7l3b
ataxin 7-like 3B
increases expression
ISO
geldanamycin results in increased expression of ATXN7L3B mRNA
CTD
PMID:26705709
NCBI chr 7:50,208,666...50,212,190
Ensembl chr 7:50,208,676...50,212,190
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
ISO
[geldanamycin co-treated with Bortezomib] results in decreased expression of BCL2 protein; geldanamycin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA] geldanamycin results in decreased expression of BCL2 protein
CTD
PMID:15781649 PMID:28673683 PMID:37586545
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Bcl2l1
Bcl2-like 1
decreases response to substance multiple interactions
ISO
BCL2L1 protein results in decreased susceptibility to geldanamycin [geldanamycin co-treated with Bortezomib] results in decreased expression of BCL2L1 protein
CTD
PMID:15781649
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
G
Bcor
BCL6 co-repressor
increases expression
ISO
geldanamycin results in increased expression of BCOR mRNA
CTD
PMID:26705709
NCBI chr X:13,282,431...13,402,254
Ensembl chr X:13,360,376...13,402,254
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Bdp1
BDP1 general transcription factor IIIB subunit
increases expression
ISO
geldanamycin results in increased expression of BDP1 mRNA
CTD
PMID:26705709
NCBI chr 2:33,112,518...33,204,270
Ensembl chr 2:33,112,518...33,204,241
G
Birc2
baculoviral IAP repeat-containing 2
multiple interactions
ISO
[geldanamycin co-treated with Bortezomib] results in decreased expression of BIRC2 protein
CTD
PMID:15781649
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
G
Bltp2
bridge-like lipid transfer protein family member 2
increases expression
ISO
geldanamycin results in increased expression of BLTP2 mRNA
CTD
PMID:26705709
NCBI chr10:63,654,072...63,683,282
Ensembl chr10:63,654,104...63,683,282
G
Bod1l1
biorientation of chromosomes in cell division 1-like 1
increases expression
ISO
geldanamycin results in increased expression of BOD1L1 mRNA
CTD
PMID:26705709
NCBI chr14:73,320,880...73,375,662
Ensembl chr14:73,320,832...73,375,658
G
C17h5orf24
similar to human chromosome 5 open reading frame 24
increases expression
ISO
geldanamycin results in increased expression of C5ORF24 mRNA
CTD
PMID:26705709
NCBI chr17:8,928,209...8,938,126
Ensembl chr17:8,929,936...8,932,379
G
C2h5orf22
similar to human chromosome 5 open reading frame 22
increases expression
ISO
geldanamycin results in increased expression of C5ORF22 mRNA
CTD
PMID:26705709
NCBI chr 2:63,576,348...63,591,764
Ensembl chr 2:63,576,348...63,591,585
G
Cab39
calcium binding protein 39
increases expression
ISO
geldanamycin results in increased expression of CAB39 mRNA
CTD
PMID:26705709
NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542
G
Cald1
caldesmon 1
increases expression
ISO
geldanamycin results in increased expression of CALD1 mRNA
CTD
PMID:26705709
NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085
G
Cask
calcium/calmodulin dependent serine protein kinase
increases expression
ISO
geldanamycin results in increased expression of CASK mRNA
CTD
PMID:26705709
NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948
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Casp3
caspase 3
multiple interactions increases activity
ISO
Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP3 protein]; geldanamycin inhibits the reaction [Demecolcine results in increased activity of CASP3 protein]; geldanamycin inhibits the reaction [Nicotine results in increased activity of CASP3 protein]
CTD
PMID:12115584 PMID:12530016 PMID:14576064 PMID:24998639
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp7
caspase 7
multiple interactions increases activity
ISO
Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]
CTD
PMID:24998639
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
G
Casp9
caspase 9
multiple interactions
ISO
geldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein]
CTD
PMID:16311509
Ensembl chr 5:159,391,188...159,409,648
G
Cbl
Cbl proto-oncogene
increases expression
ISO
geldanamycin results in increased expression of CBL mRNA
CTD
PMID:26705709
NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067
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Ccdc186
coiled-coil domain containing 186
increases expression
ISO
geldanamycin results in increased expression of CCDC186 mRNA
CTD
PMID:26705709
NCBI chr 1:265,840,429...265,878,082
Ensembl chr 1:265,843,039...265,877,131
G
Ccnd1
cyclin D1
multiple interactions decreases expression
ISO
[geldanamycin co-treated with Bortezomib] results in decreased expression of CCND1 protein geldanamycin results in decreased expression of CCND1 mRNA; geldanamycin results in decreased expression of CCND1 protein
CTD
PMID:15781649 PMID:17959518 PMID:24211270
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccnd2
cyclin D2
increases expression
ISO
geldanamycin results in increased expression of CCND2 mRNA
CTD
PMID:26705709
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301 Ensembl chr 4:161,653,048...161,680,301
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Ccne2
cyclin E2
increases expression
ISO
geldanamycin results in increased expression of CCNE2 mRNA
CTD
PMID:26705709
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
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Ccnk
cyclin K
increases expression
ISO
geldanamycin results in increased expression of CCNK mRNA
CTD
PMID:26705709
NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:132,854,700...132,877,602
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Cdc27
cell division cycle 27
increases expression
ISO
geldanamycin results in increased expression of CDC27 mRNA
CTD
PMID:26705709
NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,900,684...89,949,770
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Cdc37
cell division cycle 37, HSP90 cochaperone
multiple interactions
ISO
geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CDC37 protein]
CTD
PMID:17223712
NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931
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Cdca2
cell division cycle associated 2
increases expression
ISO
geldanamycin results in increased expression of CDCA2 mRNA
CTD
PMID:26705709
NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639
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Cdh1
cadherin 1
multiple interactions increases expression
ISO
geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]; IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]]; IL24 protein promotes the reaction [geldanamycin results in increased expression of CDH1 protein]
CTD
PMID:17024233
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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Cdh4
cadherin 4
increases expression
ISO
geldanamycin results in increased expression of CDH4 mRNA
CTD
PMID:26705709
NCBI chr 3:186,902,763...187,381,020
Ensembl chr 3:186,902,751...187,381,020
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Cdk13
cyclin-dependent kinase 13
increases expression
ISO
geldanamycin results in increased expression of CDK13 mRNA
CTD
PMID:26705709
NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257
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Cdk14
cyclin-dependent kinase 14
increases expression
ISO
geldanamycin results in increased expression of CDK14 mRNA
CTD
PMID:26705709
NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651
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Cdk4
cyclin-dependent kinase 4
decreases expression
ISO
geldanamycin results in decreased expression of CDK4 protein
CTD
PMID:28673683
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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Cdk6
cyclin-dependent kinase 6
increases expression
ISO
geldanamycin results in increased expression of CDK6 mRNA
CTD
PMID:26705709
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
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Cebpb
CCAAT/enhancer binding protein beta
multiple interactions
EXP
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]]
CTD
PMID:11133817
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
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Cep89
centrosomal protein 89
increases expression
ISO
geldanamycin results in increased expression of CEP89 mRNA
CTD
PMID:26705709
NCBI chr 1:97,195,116...97,237,015
Ensembl chr 1:97,195,135...97,237,016
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Cep95
centrosomal protein 95
increases expression
ISO
geldanamycin results in increased expression of CEP95 mRNA
CTD
PMID:26705709
NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810
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Cers6
ceramide synthase 6
increases expression
ISO
geldanamycin results in increased expression of CERS6 mRNA
CTD
PMID:26705709
NCBI chr 3:74,038,520...74,287,544
Ensembl chr 3:74,038,851...74,287,544
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Cftr
CF transmembrane conductance regulator
multiple interactions
ISO
geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]
CTD
PMID:18230692
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
increases degradation
ISO
geldanamycin results in increased degradation of CHUK protein
CTD
PMID:15930313
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
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Clip1
CAP-GLY domain containing linker protein 1
increases expression
ISO
geldanamycin results in increased expression of CLIP1 mRNA
CTD
PMID:26705709
NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779
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Clk4
CDC-like kinase 4
increases expression
ISO
geldanamycin results in increased expression of CLK4 mRNA
CTD
PMID:26705709
NCBI chr10:36,024,364...36,042,366
Ensembl chr10:36,024,427...36,042,372
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Col12a1
collagen type XII alpha 1 chain
increases expression
ISO
geldanamycin results in increased expression of COL12A1 mRNA
CTD
PMID:26705709
NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711
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Col25a1
collagen type XXV alpha 1 chain
increases expression
ISO
geldanamycin results in increased expression of COL25A1 mRNA
CTD
PMID:26705709
NCBI chr 2:221,429,378...221,828,536
Ensembl chr 2:221,429,958...221,828,535
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Col8a1
collagen type VIII alpha 1 chain
increases expression
ISO
geldanamycin results in increased expression of COL8A1 mRNA
CTD
PMID:26705709
NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229
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Cpap
centrosome assembly and centriole elongation protein
increases expression
ISO
geldanamycin results in increased expression of CPAP mRNA
CTD
PMID:26705709
NCBI chr15:34,742,838...34,806,020
Ensembl chr15:34,742,838...34,802,421
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Cpne3
copine 3
increases expression
ISO
geldanamycin results in increased expression of CPNE3 mRNA
CTD
PMID:26705709
NCBI chr 5:37,811,566...37,860,840
Ensembl chr 5:37,811,566...37,861,062
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Crcp
CGRP receptor component
increases expression
ISO
geldanamycin results in increased expression of CRCP mRNA
CTD
PMID:26705709
NCBI chr12:32,260,108...32,315,116
Ensembl chr12:32,260,143...32,315,237
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Csk
C-terminal Src kinase
multiple interactions decreases activity
ISO
geldanamycin inhibits the reaction [CSK protein results in increased susceptibility to Tetrachlorodibenzodioxin]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein]] geldanamycin results in decreased activity of CSK protein
CTD
PMID:9664232
NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:66,925,651...66,930,274
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Csnk2a1
casein kinase 2 alpha 1
increases expression
ISO
geldanamycin results in increased expression of CSNK2A1 mRNA
CTD
PMID:26705709
NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698
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Ctdspl2
CTD small phosphatase like 2
increases expression
ISO
geldanamycin results in increased expression of CTDSPL2 mRNA
CTD
PMID:26705709
NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232
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Ctnna1
catenin alpha 1
increases expression
ISO
geldanamycin results in increased expression of CTNNA1 mRNA
CTD
PMID:26705709
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
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Ctnnb1
catenin beta 1
multiple interactions
ISO
geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]; IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]]
CTD
PMID:17024233
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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Cul5
cullin 5
increases expression
ISO
geldanamycin results in increased expression of CUL5 mRNA
CTD
PMID:26705709
NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases expression
ISO
geldanamycin results in increased expression of CYP17A1 mRNA
CTD
PMID:15711029
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD
PMID:12237327 PMID:20057149
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Ddr2
discoidin domain receptor tyrosine kinase 2
increases expression
ISO
geldanamycin results in increased expression of DDR2 mRNA
CTD
PMID:26705709
NCBI chr13:84,726,412...84,851,032
Ensembl chr13:84,731,180...84,850,288
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Ddx17
DEAD-box helicase 17
increases expression
ISO
geldanamycin results in increased expression of DDX17 mRNA
CTD
PMID:26705709
NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747
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Ddx3x
DEAD-box helicase 3, X-linked
increases expression increases degradation
ISO
geldanamycin results in increased expression of DDX3X mRNA geldanamycin results in increased degradation of DDX3X protein
CTD
PMID:26705709 PMID:30821613
NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983
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Ddx42
DEAD-box helicase 42
increases expression
ISO
geldanamycin results in increased expression of DDX42 mRNA
CTD
PMID:26705709
NCBI chr10:91,648,719...91,680,730
Ensembl chr10:91,648,248...91,680,729
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Ddx6
DEAD-box helicase 6
increases expression
ISO
geldanamycin results in increased expression of DDX6 mRNA
CTD
PMID:26705709
NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977
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Dhx9
DExH-box helicase 9
increases expression
ISO
geldanamycin results in increased expression of DHX9 mRNA
CTD
PMID:26705709
NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546
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Dip2a
disco-interacting protein 2 homolog A
increases expression
ISO
geldanamycin results in increased expression of DIP2A mRNA
CTD
PMID:26705709
NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,038...12,370,532
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Dlg1
discs large MAGUK scaffold protein 1
increases expression
ISO
geldanamycin results in increased expression of DLG1 mRNA
CTD
PMID:26705709
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797
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Dmd
dystrophin
increases expression
ISO
geldanamycin results in increased expression of DMD mRNA
CTD
PMID:26705709
NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835
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Dnajc13
DnaJ heat shock protein family (Hsp40) member C13
increases expression
ISO
geldanamycin results in increased expression of DNAJC13 mRNA
CTD
PMID:26705709
NCBI chr 8:113,646,573...113,756,104
Ensembl chr 8:113,646,573...113,756,104
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Dst
dystonin
increases expression
ISO
geldanamycin results in increased expression of DST mRNA
CTD
PMID:26705709
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
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E2f3
E2F transcription factor 3
increases expression
ISO
geldanamycin results in increased expression of E2F3 mRNA
CTD
PMID:26705709
NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
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Edil3
EGF like repeats and discoidin domains 3
increases expression
ISO
geldanamycin results in increased expression of EDIL3 mRNA
CTD
PMID:26705709
NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379
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Edn1
endothelin 1
increases expression
ISO
geldanamycin results in increased expression of EDN1 mRNA
CTD
PMID:26705709
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
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Eea1
early endosome antigen 1
increases expression
ISO
geldanamycin results in increased expression of EEA1 mRNA
CTD
PMID:26705709
NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476
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Egf
epidermal growth factor
multiple interactions
EXP ISO
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]
CTD
PMID:9605431 PMID:9664232
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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Egfr
epidermal growth factor receptor
multiple interactions decreases expression
ISO EXP
geldanamycin inhibits the reaction [TNF protein results in increased expression of EGFR mRNA]; geldanamycin promotes the reaction [Sulfasalazine results in decreased expression of EGFR protein] geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] geldanamycin results in decreased expression of EGFR protein
CTD
PMID:9605431 PMID:9664232 PMID:20007406 PMID:37586545
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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Ehbp1
EH domain binding protein 1
increases expression
ISO
geldanamycin results in increased expression of EHBP1 mRNA
CTD
PMID:26705709
NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579
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Ehmt1
euchromatic histone lysine methyltransferase 1
increases expression
ISO
geldanamycin results in increased expression of EHMT1 mRNA
CTD
PMID:26705709
NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349
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Eif4a1
eukaryotic translation initiation factor 4A1
increases degradation
ISO
geldanamycin results in increased degradation of EIF4A1 protein
CTD
PMID:30821613
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
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Ell2
elongation factor for RNA polymerase II 2
increases expression
ISO
geldanamycin results in increased expression of ELL2 mRNA
CTD
PMID:26705709
NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:6,921,771...7,016,199
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Epb41l5
erythrocyte membrane protein band 4.1 like 5
increases expression
ISO
geldanamycin results in increased expression of EPB41L5 mRNA
CTD
PMID:26705709
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
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Eprs1
glutamyl-prolyl-tRNA synthetase 1
increases expression
ISO
geldanamycin results in increased expression of EPRS1 mRNA
CTD
PMID:26705709
NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509
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Erbb2
erb-b2 receptor tyrosine kinase 2
increases degradation multiple interactions decreases expression
ISO
geldanamycin results in increased degradation of ERBB2 protein [geldanamycin binds to HSP90B1 protein] inhibits the reaction [HSP90B1 protein binds to ERBB2 protein]; geldanamycin inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]]; geldanamycin results in decreased expression of and results in increased ubiquitination of ERBB2 protein; Quercetin promotes the reaction [geldanamycin results in decreased expression of and results in increased ubiquitination of ERBB2 protein] geldanamycin results in decreased expression of ERBB2 protein
CTD
PMID:8617772 PMID:11071886 PMID:17959518 PMID:18655187 PMID:24450340
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
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Ercc6l2
ERCC excision repair 6 like 2
increases expression
ISO
geldanamycin results in increased expression of ERCC6L2 mRNA
CTD
PMID:26705709
NCBI chr17:1,055,881...1,323,207
Ensembl chr17:1,222,139...1,316,056
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Esco1
establishment of sister chromatid cohesion N-acetyltransferase 1
increases expression
ISO
geldanamycin results in increased expression of ESCO1 mRNA
CTD
PMID:26705709
NCBI chr18:1,904,748...1,959,609
Ensembl chr18:1,904,762...1,959,805
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Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
increases expression
ISO
geldanamycin results in increased expression of ESCO2 mRNA
CTD
PMID:26705709
NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304 Ensembl chr15:44,210,641...44,231,304
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Esr1
estrogen receptor 1
multiple interactions decreases expression decreases stability increases degradation
ISO
geldanamycin inhibits the reaction [Estradiol binds to ESR1 protein]; geldanamycin promotes the reaction [ESR1 protein binds to STUB1 protein]; STUB1 protein promotes the reaction [geldanamycin results in increased degradation of ESR1 protein] geldanamycin results in decreased expression of ESR1 protein geldanamycin results in decreased stability of ESR1 protein
CTD
PMID:11448926 PMID:16037132 PMID:24211270
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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Ets1
ETS proto-oncogene 1, transcription factor
increases expression
ISO
geldanamycin results in increased expression of ETS1 mRNA
CTD
PMID:26705709
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
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Evi5
ecotropic viral integration site 5
increases expression
ISO
geldanamycin results in increased expression of EVI5 mRNA
CTD
PMID:26705709
NCBI chr14:2,020,524...2,166,593
Ensembl chr14:2,020,581...2,166,593
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Fancb
FA complementation group B
increases expression
ISO
geldanamycin results in increased expression of FANCB mRNA
CTD
PMID:26705709
NCBI chr X:33,035,387...33,051,993
Ensembl chr X:33,035,387...33,051,808
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Fancm
FA complementation group M
increases expression
ISO
geldanamycin results in increased expression of FANCM mRNA
CTD
PMID:26705709
NCBI chr 6:88,862,898...88,916,701
Ensembl chr 6:88,863,306...88,921,652
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Fbn1
fibrillin 1
increases expression
ISO
geldanamycin results in increased expression of FBN1 mRNA
CTD
PMID:26705709
NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283
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Fgf7
fibroblast growth factor 7
multiple interactions
ISO
geldanamycin inhibits the reaction [ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased expression of FGF7 protein]
CTD
PMID:14656992
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
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Flt1
Fms related receptor tyrosine kinase 1
increases expression
ISO
geldanamycin results in increased expression of FLT1 mRNA
CTD
PMID:26705709
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
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Fn1
fibronectin 1
increases expression
ISO
geldanamycin results in increased expression of FN1 mRNA
CTD
PMID:26705709
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
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Fryl
FRY like transcription coactivator
increases expression
ISO
geldanamycin results in increased expression of FRYL mRNA
CTD
PMID:26705709
NCBI chr14:35,307,225...35,545,199
Ensembl chr14:35,310,656...35,545,147
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G3bp1
G3BP stress granule assembly factor 1
increases expression
ISO
geldanamycin results in increased expression of G3BP1 mRNA
CTD
PMID:26705709
NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931
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Galnt5
polypeptide N-acetylgalactosaminyltransferase 5
increases expression
ISO
geldanamycin results in increased expression of GALNT5 mRNA
CTD
PMID:26705709
NCBI chr 3:62,982,465...63,028,724
Ensembl chr 3:62,982,465...63,028,724
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Gls
glutaminase
increases expression
ISO
geldanamycin results in increased expression of GLS mRNA
CTD
PMID:26705709
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
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Gng12
G protein subunit gamma 12
increases expression
ISO
geldanamycin results in increased expression of GNG12 mRNA
CTD
PMID:26705709
NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476
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Golim4
golgi integral membrane protein 4
increases expression
ISO
geldanamycin results in increased expression of GOLIM4 mRNA
CTD
PMID:26705709
NCBI chr 2:162,939,429...163,031,901
Ensembl chr 2:162,939,429...163,031,901
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Gria3
glutamate ionotropic receptor AMPA type subunit 3
increases expression
ISO
geldanamycin results in increased expression of GRIA3 mRNA
CTD
PMID:26705709
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
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Gtf2a1
general transcription factor 2A subunit 1
increases expression
ISO
geldanamycin results in increased expression of GTF2A1 mRNA
CTD
PMID:26705709
NCBI chr 6:116,219,614...116,252,220
Ensembl chr 6:116,219,614...116,252,220
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H4f3
H1.3 linker histone, cluster member
increases expression
ISO
geldanamycin results in increased expression of H1-3 mRNA
CTD
PMID:26705709
NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,796,116...41,980,485
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Hacd2
3-hydroxyacyl-CoA dehydratase 2
increases expression
ISO
geldanamycin results in increased expression of HACD2 mRNA
CTD
PMID:26705709
NCBI chr11:79,175,470...79,268,975
Ensembl chr11:79,175,482...79,268,126
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Hcn1
hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
increases expression
ISO
geldanamycin results in increased expression of HCN1 mRNA
CTD
PMID:26705709
NCBI chr 2:51,228,710...51,632,806
Ensembl chr 2:51,228,710...51,632,806
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Heatr1
HEAT repeat containing 1
increases expression
ISO
geldanamycin results in increased expression of HEATR1 mRNA
CTD
PMID:26705709
NCBI chr17:62,745,008...62,785,609
Ensembl chr17:62,745,008...62,785,186
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Hectd1
HECT domain E3 ubiquitin protein ligase 1
increases expression
ISO
geldanamycin results in increased expression of HECTD1 mRNA
CTD
PMID:26705709
NCBI chr 6:74,916,803...75,003,408
Ensembl chr 6:74,916,803...75,003,408
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions decreases expression increases degradation
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]; geldanamycin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; geldanamycin inhibits the reaction [TNF protein results in increased expression of HIF1A mRNA]; lactacystin inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein] geldanamycin results in decreased expression of HIF1A protein
CTD
PMID:11980636 PMID:12811834 PMID:14726529 PMID:15319539 PMID:16432534 PMID:37586545 More...
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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Hmox1
heme oxygenase 1
multiple interactions
ISO
geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein]
CTD
PMID:25645596
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hpgd
15-hydroxyprostaglandin dehydrogenase
multiple interactions
ISO
geldanamycin inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein]
CTD
PMID:15680906
NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
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Hsf1
heat shock transcription factor 1
multiple interactions
ISO
geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin results in increased phosphorylation of and results in increased activity of HSF1 protein
CTD
PMID:10632574 PMID:25645596
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
affects binding multiple interactions
EXP ISO
geldanamycin binds to HSP90AA1 protein geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [KCNH2 protein binds to HSP90AA1 protein]; geldanamycin inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]]
CTD
PMID:12775586 PMID:17223712 PMID:18655187 PMID:21749116
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
affects binding increases expression
EXP ISO
geldanamycin binds to HSP90AB1 protein geldanamycin results in increased expression of HSP90AB1 mRNA
CTD
PMID:21749116 PMID:26705709
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
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Hsp90b1
heat shock protein 90 beta family member 1
affects binding multiple interactions
ISO
geldanamycin binds to HSP90B1 protein [geldanamycin binds to HSP90B1 protein] inhibits the reaction [HSP90B1 protein binds to ERBB2 protein]
CTD
PMID:8617772
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression multiple interactions
EXP ISO
geldanamycin results in increased expression of HSPA1A mRNA; geldanamycin results in increased expression of HSPA1A protein [geldanamycin results in increased expression of HSPA1A protein] which results in decreased susceptibility to Gentamicins
CTD
PMID:11448926 PMID:19723345 PMID:25477506
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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Hspa4
heat shock protein family A (Hsp70) member 4
increases expression multiple interactions
ISO
geldanamycin results in increased expression of HSPA4 mRNA; geldanamycin results in increased expression of HSPA4 protein [geldanamycin results in increased expression of HSPA4 protein] which results in decreased susceptibility to Doxorubicin
CTD
PMID:16311509 PMID:26705709
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases expression affects expression
ISO
Bortezomib promotes the reaction [geldanamycin results in increased expression of HSPA5 protein]; geldanamycin promotes the reaction [Bortezomib results in increased expression of HSPA5 protein] geldanamycin affects the expression of HSPA5 protein
CTD
PMID:14576064 PMID:15141013
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Hspd1
heat shock protein family D (Hsp60) member 1
increases expression
ISO
geldanamycin results in increased expression of HSPD1 mRNA
CTD
PMID:26705709
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
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Htt
huntingtin
multiple interactions
ISO
geldanamycin inhibits the reaction [HTT protein binds to HTT protein]
CTD
PMID:11406612
NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668
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Hycc1
hyccin PI4KA lipid kinase complex subunit 1
increases expression
ISO
geldanamycin results in increased expression of HYCC1 mRNA
CTD
PMID:26705709
NCBI chr 4:12,024,692...12,131,504
Ensembl chr 4:12,024,739...12,131,501
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Ice2
interactor of little elongation complex ELL subunit 2
increases expression
ISO
geldanamycin results in increased expression of ICE2 mRNA
CTD
PMID:26705709
NCBI chr 8:78,921,962...78,965,983
Ensembl chr 8:78,924,421...78,966,200
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Il1b
interleukin 1 beta
multiple interactions
ISO EXP
geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA] geldanamycin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA] geldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein]
CTD
PMID:12571865 PMID:15808840 PMID:37586545
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il24
interleukin 24
multiple interactions
ISO
IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]]; IL24 protein promotes the reaction [geldanamycin results in increased expression of CDH1 protein]
CTD
PMID:17024233
NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
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Il6
interleukin 6
multiple interactions
ISO
geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]
CTD
PMID:12571865
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Il6st
interleukin 6 cytokine family signal transducer
increases expression
ISO
geldanamycin results in increased expression of IL6ST mRNA
CTD
PMID:26705709
NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
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Inhba
inhibin subunit beta A
increases expression
ISO
geldanamycin results in increased expression of INHBA mRNA
CTD
PMID:26705709
NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508
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Inpp5a
inositol polyphosphate-5-phosphatase A
increases expression
ISO
geldanamycin results in increased expression of INPP5A mRNA
CTD
PMID:26705709
NCBI chr 1:203,619,676...203,810,035
Ensembl chr 1:203,619,637...203,810,028
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Ipo8
importin 8
increases expression
ISO
geldanamycin results in increased expression of IPO8 mRNA
CTD
PMID:26705709
NCBI chr 4:183,460,583...183,529,259
Ensembl chr 4:183,460,583...183,524,519
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Iqgap1
IQ motif containing GTPase activating protein 1
increases expression
ISO
geldanamycin results in increased expression of IQGAP1 mRNA
CTD
PMID:26705709
NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:144,088,793...144,179,043
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Itga1
integrin subunit alpha 1
increases expression
ISO
geldanamycin results in increased expression of ITGA1 mRNA
CTD
PMID:26705709
NCBI chr 2:48,379,181...48,545,336
Ensembl chr 2:48,386,249...48,545,284
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Itgb3
integrin subunit beta 3
increases expression
ISO
geldanamycin results in increased expression of ITGB3 mRNA
CTD
PMID:26705709
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
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Itprid2
ITPR interacting domain containing 2
increases expression
ISO
geldanamycin results in increased expression of SSFA2 mRNA
CTD
PMID:26705709
NCBI chr 3:84,943,572...84,980,993
Ensembl chr 3:84,939,808...84,980,899
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Jmjd1c
jumonji domain containing 1C
increases expression
ISO
geldanamycin results in increased expression of JMJD1C mRNA
CTD
PMID:26705709
NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,330,990...21,461,916
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Kat6a
lysine acetyltransferase 6A
increases expression
ISO
geldanamycin results in increased expression of KAT6A mRNA
CTD
PMID:26705709
NCBI chr16:75,787,411...75,868,584
Ensembl chr16:75,787,411...75,866,099
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Kbtbd2
kelch repeat and BTB domain containing 2
increases expression
ISO
geldanamycin results in increased expression of KBTBD2 mRNA
CTD
PMID:26705709
NCBI chr 4:87,358,133...87,380,399
Ensembl chr 4:87,358,133...87,380,399
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Kcnh2
potassium voltage-gated channel subfamily H member 2
affects localization decreases activity increases degradation multiple interactions decreases expression
ISO
geldanamycin affects the localization of KCNH2 protein geldanamycin results in decreased activity of KCNH2 protein geldanamycin results in increased degradation of KCNH2 protein geldanamycin inhibits the reaction [KCNH2 protein binds to HSP90AA1 protein] geldanamycin results in decreased expression of KCNH2 protein modified form
CTD
PMID:12775586 PMID:24052561
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
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Kdm6a
lysine demethylase 6A
increases expression
ISO
geldanamycin results in increased expression of KDM6A mRNA
CTD
PMID:26705709
NCBI chr X:6,920,374...7,060,027
Ensembl chr X:6,920,343...7,059,960
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Kirrel1
kirre like nephrin family adhesion molecule 1
increases expression
ISO
geldanamycin results in increased expression of KIRREL1 mRNA
CTD
PMID:26705709
NCBI chr 2:174,819,564...174,912,998
Ensembl chr 2:174,819,572...174,912,960
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Klf12
KLF transcription factor 12
increases expression
ISO
geldanamycin results in increased expression of KLF12 mRNA
CTD
PMID:26705709
NCBI chr15:83,037,548...83,469,998
Ensembl chr15:83,045,463...83,670,640
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Klhl24
kelch-like family member 24
increases expression
ISO
geldanamycin results in increased expression of KLHL24 mRNA
CTD
PMID:26705709
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050
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Kmt2a
lysine methyltransferase 2A
increases expression
ISO
geldanamycin results in increased expression of KMT2A mRNA
CTD
PMID:26705709
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317
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Knl1
kinetochore scaffold 1
increases expression
ISO
geldanamycin results in increased expression of KNL1 mRNA
CTD
PMID:26705709
NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774
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Lama4
laminin subunit alpha 4
increases expression
ISO
geldanamycin results in increased expression of LAMA4 mRNA
CTD
PMID:26705709
NCBI chr20:43,946,898...44,087,972
Ensembl chr20:43,946,898...44,087,972
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Larp1b
La ribonucleoprotein 1B
increases expression
ISO
geldanamycin results in increased expression of LARP1B mRNA
CTD
PMID:26705709
NCBI chr 2:125,860,935...125,897,189
Ensembl chr 2:125,863,997...125,897,189
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Larp4
La ribonucleoprotein 4
increases expression
ISO
geldanamycin results in increased expression of LARP4 mRNA
CTD
PMID:26705709
NCBI chr 7:132,983,276...133,031,514
Ensembl chr 7:132,980,385...133,029,633
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Lars1
leucyl-tRNA synthetase 1
increases expression
ISO
geldanamycin results in increased expression of LARS1 mRNA
CTD
PMID:26705709
NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,452,561...34,506,938
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Lima1
LIM domain and actin binding 1
increases expression
ISO
geldanamycin results in increased expression of LIMA1 mRNA
CTD
PMID:26705709
NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386
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Lin7a
lin-7 homolog A, crumbs cell polarity complex component
increases expression
ISO
geldanamycin results in increased expression of LIN7A mRNA
CTD
PMID:26705709
NCBI chr 7:44,473,568...44,629,074
Ensembl chr 7:44,473,347...44,625,208
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Lman1
lectin, mannose-binding, 1
increases expression
ISO
geldanamycin results in increased expression of LMAN1 mRNA
CTD
PMID:26705709
NCBI chr18:61,778,971...61,800,960
Ensembl chr18:61,772,917...61,800,820
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Lmo7
LIM domain 7
increases expression
ISO
geldanamycin results in increased expression of LMO7 mRNA
CTD
PMID:26705709
NCBI chr15:84,981,689...85,184,554
Ensembl chr15:84,981,735...85,184,551
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Lpp
LIM domain containing preferred translocation partner in lipoma
increases expression
ISO
geldanamycin results in increased expression of LPP mRNA
CTD
PMID:26705709
NCBI chr11:89,292,060...89,933,973
Ensembl chr11:89,305,187...89,805,264
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Lrrc58
leucine rich repeat containing 58
increases expression
ISO
geldanamycin results in increased expression of LRRC58 mRNA
CTD
PMID:26705709
NCBI chr11:76,355,987...76,368,309
Ensembl chr11:76,344,923...76,368,309
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Lsm14b
LSM family member 14B
increases expression
ISO
geldanamycin results in increased expression of LSM14B mRNA
CTD
PMID:26705709
NCBI chr 3:187,503,251...187,514,041
Ensembl chr 3:187,503,045...187,512,473
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Man1a2
mannosidase, alpha, class 1A, member 2
increases expression
ISO
geldanamycin results in increased expression of MAN1A2 mRNA
CTD
PMID:26705709
NCBI chr 2:190,636,134...190,784,975
Ensembl chr 2:190,615,094...190,784,975
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Map1b
microtubule-associated protein 1B
increases expression
ISO
geldanamycin results in increased expression of MAP1B mRNA
CTD
PMID:26705709
NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094
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Map2k1
mitogen activated protein kinase kinase 1
multiple interactions decreases phosphorylation
ISO
geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] geldanamycin results in decreased phosphorylation of MAP2K1 protein
CTD
PMID:8816498 PMID:19167484
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
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Map2k2
mitogen activated protein kinase kinase 2
decreases phosphorylation
ISO
geldanamycin results in decreased phosphorylation of MAP2K2 protein
CTD
PMID:19167484
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
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Map3k1
mitogen-activated protein kinase kinase kinase 1
increases expression
ISO
geldanamycin results in increased expression of MAP3K1 mRNA
CTD
PMID:26705709
NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897
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Map3k5
mitogen-activated protein kinase kinase kinase 5
increases expression
ISO
geldanamycin results in increased expression of MAP3K5 mRNA
CTD
PMID:26705709
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898
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Map4k5
mitogen-activated protein kinase kinase kinase kinase 5
increases expression
ISO
geldanamycin results in increased expression of MAP4K5 mRNA
CTD
PMID:26705709
NCBI chr 6:94,020,079...94,112,943
Ensembl chr 6:94,020,079...94,112,943
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Mapk1
mitogen activated protein kinase 1
multiple interactions decreases expression decreases phosphorylation
ISO
geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Heptachlor results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein] geldanamycin results in decreased expression of MAPK1 mRNA geldanamycin results in decreased phosphorylation of MAPK1 protein geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD
PMID:8816498 PMID:15888667 PMID:17293044 PMID:19167484 PMID:30166341
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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Mapk3
mitogen activated protein kinase 3
multiple interactions decreases phosphorylation
ISO
geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Heptachlor results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK3 protein] geldanamycin results in decreased phosphorylation of MAPK3 protein geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:8816498 PMID:15888667 PMID:17293044 PMID:19167484
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mapkapk2
MAPK activated protein kinase 2
increases expression
ISO
geldanamycin results in increased expression of MAPKAPK2 mRNA
CTD
PMID:26705709
NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326
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Matr3
matrin 3
increases expression
ISO
geldanamycin results in increased expression of MATR3 mRNA
CTD
PMID:26705709
NCBI chr18:27,428,190...27,474,421
Ensembl chr18:27,432,179...27,470,421
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Mbnl1
muscleblind-like splicing regulator 1
increases expression
ISO
geldanamycin results in increased expression of MBNL1 mRNA
CTD
PMID:26705709
NCBI chr 2:146,789,570...146,964,136
Ensembl chr 2:146,789,596...146,964,134
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Mbnl2
muscleblind-like splicing regulator 2
increases expression
ISO
geldanamycin results in increased expression of MBNL2 mRNA
CTD
PMID:26705709
NCBI chr15:103,792,134...103,949,827
Ensembl chr15:103,792,152...103,949,827
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Mbtd1
mbt domain containing 1
increases expression
ISO
geldanamycin results in increased expression of MBTD1 mRNA
CTD
PMID:26705709
NCBI chr10:79,336,041...79,392,315
Ensembl chr10:79,335,235...79,392,315
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Mcam
melanoma cell adhesion molecule
increases expression
ISO
geldanamycin results in increased expression of MCAM mRNA
CTD
PMID:26705709
NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406
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Mcm4
minichromosome maintenance complex component 4
increases expression
ISO
geldanamycin results in increased expression of MCM4 mRNA
CTD
PMID:26705709
NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
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Mdfic
MyoD family inhibitor domain containing
increases expression
ISO
geldanamycin results in increased expression of MDFIC mRNA
CTD
PMID:26705709
NCBI chr 4:44,938,301...45,018,157
Ensembl chr 4:44,938,480...45,018,156
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Mdm2
MDM2 proto-oncogene
increases expression
ISO
geldanamycin results in increased expression of MDM2 mRNA
CTD
PMID:26705709
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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Med13
mediator complex subunit 13
increases expression
ISO
geldanamycin results in increased expression of MED13 mRNA
CTD
PMID:26705709
NCBI chr10:71,584,354...71,674,614
Ensembl chr10:71,584,354...71,673,901
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Med7
mediator complex subunit 7
increases expression
ISO
geldanamycin results in increased expression of MED7 mRNA
CTD
PMID:26705709
NCBI chr10:31,343,613...31,359,192
Ensembl chr10:31,343,361...31,361,017
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Met
MET proto-oncogene, receptor tyrosine kinase
increases expression
ISO
geldanamycin results in increased expression of MET mRNA
CTD
PMID:26705709
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
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Mettl16
methyltransferase 16, RNA N6-adenosine
increases expression
ISO
geldanamycin results in increased expression of METTL16 mRNA
CTD
PMID:26705709
NCBI chr10:60,139,317...60,185,438
Ensembl chr10:60,139,330...60,187,571
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Mgmt
O-6-methylguanine-DNA methyltransferase
multiple interactions
ISO
geldanamycin results in increased expression of and results in increased activity of MGMT protein
CTD
PMID:16950796
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
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Mier1
MIER1 transcriptional regulator
increases expression
ISO
geldanamycin results in increased expression of MIER1 mRNA
CTD
PMID:26705709
NCBI chr 5:123,105,114...123,156,653
Ensembl chr 5:123,104,915...123,156,656
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Mir21
microRNA 21
increases expression
ISO
geldanamycin results in increased expression of MIR21 mRNA
CTD
PMID:26705709
NCBI chr10:71,902,600...71,902,691
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Mis18bp1
MIS18 binding protein 1
increases expression
ISO
geldanamycin results in increased expression of MIS18BP1 mRNA
CTD
PMID:26705709
NCBI chr 6:88,918,743...88,968,225
Ensembl chr 6:88,918,745...88,967,629
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Mmp1
matrix metallopeptidase 1
multiple interactions decreases expression
ISO
[geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA geldanamycin results in decreased expression of MMP1 mRNA
CTD
PMID:12724357 PMID:26705709
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
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Mmp16
matrix metallopeptidase 16
increases expression
ISO
geldanamycin results in increased expression of MMP16 mRNA
CTD
PMID:26705709
NCBI chr 5:36,109,265...36,353,252
Ensembl chr 5:36,109,265...36,353,252
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Mt-nd6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
increases expression
ISO
geldanamycin results in increased expression of ND6 mRNA
CTD
PMID:26705709
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049
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Myo5a
myosin VA
increases expression
ISO
geldanamycin results in increased expression of MYO5A mRNA
CTD
PMID:26705709
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265
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Myocd
myocardin
increases expression
ISO
geldanamycin results in increased expression of MYOCD mRNA
CTD
PMID:26705709
NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819
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Mzt1
mitotic spindle organizing protein 1
increases expression
ISO
geldanamycin results in increased expression of MZT1 mRNA
CTD
PMID:26705709
NCBI chr15:82,195,128...82,205,436
Ensembl chr15:82,195,128...82,205,436
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Nasp
nuclear autoantigenic sperm protein
increases expression
ISO
geldanamycin results in increased expression of NASP mRNA
CTD
PMID:26705709
NCBI chr 5:135,294,599...135,319,992
Ensembl chr 5:135,294,032...135,319,591
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Nbas
NBAS subunit of NRZ tethering complex
increases expression
ISO
geldanamycin results in increased expression of NBAS mRNA
CTD
PMID:26705709
NCBI chr 6:41,777,253...42,081,895
Ensembl chr 6:41,755,851...42,081,895
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Ncoa2
nuclear receptor coactivator 2
increases expression
ISO
geldanamycin results in increased expression of NCOA2 mRNA
CTD
PMID:26705709
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases expression
ISO
geldanamycin results in increased expression of NEDD9 mRNA
CTD
PMID:26705709
NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668
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Nes
nestin
increases expression
ISO
geldanamycin results in increased expression of NES mRNA
CTD
PMID:26705709
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
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Nf1
neurofibromin 1
increases expression
ISO
geldanamycin results in increased expression of NF1 mRNA
CTD
PMID:26705709
NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946
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Nf2
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
increases expression
ISO
geldanamycin results in increased expression of NF2 mRNA
CTD
PMID:26705709
NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151
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Nfat5
nuclear factor of activated T-cells 5
increases expression
ISO
geldanamycin results in increased expression of NFAT5 mRNA
CTD
PMID:26705709
NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418
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Nipbl
NIPBL, cohesin loading factor
increases expression
ISO
geldanamycin results in increased expression of NIPBL mRNA
CTD
PMID:26705709
NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277
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Nktr
natural killer cell triggering receptor
increases expression
ISO
geldanamycin results in increased expression of NKTR mRNA
CTD
PMID:26705709
NCBI chr 8:130,255,541...130,298,001
Ensembl chr 8:130,259,461...130,298,008
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Nos2
nitric oxide synthase 2
multiple interactions decreases expression
EXP ISO
geldanamycin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [geldanamycin results in decreased expression of NOS2 mRNA] geldanamycin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]
CTD
PMID:11835313 PMID:15583003 PMID:37586545
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Npr3
natriuretic peptide receptor 3
increases expression
ISO
geldanamycin results in increased expression of NPR3 mRNA
CTD
PMID:26705709
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases reduction
ISO
NQO1 protein results in increased reduction of geldanamycin
CTD
PMID:16825487
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Nr2c2
nuclear receptor subfamily 2, group C, member 2
increases expression
ISO
geldanamycin results in increased expression of NR2C2 mRNA
CTD
PMID:26705709
NCBI chr 4:126,167,350...126,223,942
Ensembl chr 4:126,168,085...126,223,942
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Nrk
Nik related kinase
increases expression
ISO
geldanamycin results in increased expression of NRK mRNA
CTD
PMID:26705709
NCBI chr X:107,159,154...107,256,417
Ensembl chr X:107,159,233...107,256,417
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Osbpl8
oxysterol binding protein-like 8
increases expression
ISO
geldanamycin results in increased expression of OSBPL8 mRNA
CTD
PMID:26705709
NCBI chr 7:48,483,259...48,636,151
Ensembl chr 7:48,483,022...48,636,151
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Otud4
OTU deubiquitinase 4
increases expression
ISO
geldanamycin results in increased expression of OTUD4 mRNA
CTD
PMID:26705709
NCBI chr19:45,141,043...45,184,136
Ensembl chr19:45,141,043...45,184,136
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Oxtr
oxytocin receptor
increases expression
ISO
geldanamycin results in increased expression of OXTR mRNA
CTD
PMID:26705709
NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750
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P2rx1
purinergic receptor P2X 1
multiple interactions
EXP
geldanamycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]
CTD
PMID:11930156
NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164
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Pappa
pappalysin 1
increases expression
ISO
geldanamycin results in increased expression of PAPPA mRNA
CTD
PMID:26705709
NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases degradation
ISO
geldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Tretinoin inhibits the reaction [geldanamycin results in increased degradation of PARP1 protein]
CTD
PMID:16311509 PMID:17293044
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pcbp2
poly(rC) binding protein 2
increases expression
ISO
geldanamycin results in increased expression of PCBP2 mRNA
CTD
PMID:26705709
NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412
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Pcm1
pericentriolar material 1
increases expression
ISO
geldanamycin results in increased expression of PCM1 mRNA
CTD
PMID:26705709
NCBI chr16:57,711,833...57,808,842
Ensembl chr16:57,711,833...57,808,599
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Pde4dip
phosphodiesterase 4D interacting protein
increases expression
ISO
geldanamycin results in increased expression of PDE4DIP mRNA
CTD
PMID:26705709
NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869
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Pdgfa
platelet derived growth factor subunit A
increases expression
ISO
geldanamycin results in increased expression of PDGFA mRNA
CTD
PMID:26705709
NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322
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Peg10
paternally expressed 10
increases expression
ISO
geldanamycin results in increased expression of PEG10 mRNA
CTD
PMID:26705709
NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:33,817,190...33,819,166 Ensembl chr 4:33,817,190...33,819,166
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Pgr
progesterone receptor
decreases expression
ISO
geldanamycin results in decreased expression of PGR protein
CTD
PMID:11448926
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
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Phactr2
phosphatase and actin regulator 2
increases expression
ISO
geldanamycin results in increased expression of PHACTR2 mRNA
CTD
PMID:26705709
NCBI chr 1:9,411,412...9,680,648
Ensembl chr 1:9,418,085...9,680,583
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Phldb2
pleckstrin homology-like domain, family B, member 2
increases expression
ISO
geldanamycin results in increased expression of PHLDB2 mRNA
CTD
PMID:26705709
NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734
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Phtf2
putative homeodomain transcription factor 2
increases expression
ISO
geldanamycin results in increased expression of PHTF2 mRNA
CTD
PMID:26705709
NCBI chr 4:15,107,341...15,222,683
Ensembl chr 4:15,107,373...15,222,692
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Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
increases expression
ISO
geldanamycin results in increased expression of PIK3CA mRNA
CTD
PMID:26705709
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
increases expression
ISO
geldanamycin results in increased expression of PIK3R1 mRNA
CTD
PMID:26705709
NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
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Pkm
pyruvate kinase M1/2
multiple interactions
ISO
geldanamycin inhibits the reaction [sodium arsenite results in increased expression of PKM protein]
CTD
PMID:38977090
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
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Plau
plasminogen activator, urokinase
multiple interactions
ISO
[geldanamycin co-treated with PTHLH protein modified form] results in decreased expression of PLAU mRNA
CTD
PMID:12724357
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
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Plppr4
phospholipid phosphatase related 4
increases expression
ISO
geldanamycin results in increased expression of PLPPR4 mRNA
CTD
PMID:26705709
NCBI chr 2:208,056,206...208,097,191
Ensembl chr 2:208,056,211...208,097,191
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Plxna2
plexin A2
increases expression
ISO
geldanamycin results in increased expression of PLXNA2 mRNA
CTD
PMID:26705709
NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453
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Polr2b
RNA polymerase II subunit B
decreases expression
ISO
geldanamycin results in decreased expression of POLR2B mRNA
CTD
PMID:30166341
NCBI chr14:31,151,534...31,189,222
Ensembl chr14:31,151,390...31,189,222
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Ppm1k
protein phosphatase, Mg2+/Mn2+ dependent, 1K
increases expression
ISO
geldanamycin results in increased expression of PPM1K mRNA
CTD
PMID:26705709
NCBI chr 4:88,942,226...88,969,139
Ensembl chr 4:88,942,386...88,969,136
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
multiple interactions
ISO
Bortezomib inhibits the reaction [geldanamycin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; geldanamycin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein
CTD
PMID:37481222
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
multiple interactions
ISO
Bortezomib inhibits the reaction [geldanamycin results in decreased expression of and results in decreased phosphorylation of PRKAA2 protein]; geldanamycin results in decreased expression of and results in decreased phosphorylation of PRKAA2 protein
CTD
PMID:37481222
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
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Prkg1
protein kinase cGMP-dependent 1
increases expression
ISO
geldanamycin results in increased expression of PRKG1 mRNA
CTD
PMID:26705709
NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005
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Prmt2
protein arginine methyltransferase 2
increases expression
ISO
geldanamycin results in increased expression of PRMT2 mRNA
CTD
PMID:26705709
NCBI chr20:12,391,388...12,420,096
Ensembl chr20:12,394,268...12,420,108
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Prpf6
pre-mRNA processing factor 6
increases expression
ISO
geldanamycin results in increased expression of PRPF6 mRNA
CTD
PMID:26705709
NCBI chr 3:189,084,465...189,148,705
Ensembl chr 3:189,081,794...189,152,786
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Prr14l
proline rich 14-like
increases expression
ISO
geldanamycin results in increased expression of PRR14L mRNA
CTD
PMID:26705709
NCBI chr14:82,094,360...82,160,985
Ensembl chr14:82,094,358...82,158,323
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Prrc2c
proline-rich coiled-coil 2C
increases expression
ISO
geldanamycin results in increased expression of PRRC2C mRNA
CTD
PMID:26705709
NCBI chr13:77,537,226...77,606,926
Ensembl chr13:77,537,814...77,607,001
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Psme4
proteasome activator subunit 4
increases expression
ISO
geldanamycin results in increased expression of PSME4 mRNA
CTD
PMID:26705709
NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328
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Ptar1
protein prenyltransferase alpha subunit repeat containing 1
increases expression
ISO
geldanamycin results in increased expression of PTAR1 mRNA
CTD
PMID:26705709
NCBI chr 1:230,709,731...230,753,380
Ensembl chr 1:230,709,848...230,755,620
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Ptbp3
polypyrimidine tract binding protein 3
increases expression
ISO
geldanamycin results in increased expression of PTBP3 mRNA
CTD
PMID:26705709
NCBI chr 5:79,108,376...79,194,533
Ensembl chr 5:79,108,376...79,194,508
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Ptgs1
prostaglandin-endoperoxide synthase 1
decreases expression
ISO
geldanamycin results in decreased expression of PTGS1 mRNA
CTD
PMID:26705709
NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD
PMID:11133817
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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Pthlh
parathyroid hormone-like hormone
multiple interactions
ISO
[geldanamycin co-treated with PTHLH protein modified form] results in decreased expression of PLAU mRNA; [geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA
CTD
PMID:12724357
NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454
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Ptk2
protein tyrosine kinase 2
increases degradation decreases phosphorylation
ISO
geldanamycin results in increased degradation of PTK2 protein geldanamycin results in decreased phosphorylation of PTK2 protein
CTD
PMID:9973544 PMID:12811834
NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
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Ptpn11
protein tyrosine phosphatase, non-receptor type 11
increases expression
ISO
geldanamycin results in increased expression of PTPN11 mRNA
CTD
PMID:26705709
NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577
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Ptpn12
protein tyrosine phosphatase, non-receptor type 12
increases expression
ISO
geldanamycin results in increased expression of PTPN12 mRNA
CTD
PMID:26705709
NCBI chr 4:14,913,071...14,985,084
Ensembl chr 4:14,913,218...14,985,284
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Ptpra
protein tyrosine phosphatase, receptor type, A
increases expression
ISO
geldanamycin results in increased expression of PTPRA mRNA
CTD
PMID:26705709
NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:138,098,110...138,213,126
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Ptprd
protein tyrosine phosphatase, receptor type, D
increases expression
ISO
geldanamycin results in increased expression of PTPRD mRNA
CTD
PMID:26705709
NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903
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Pygo1
pygopus family PHD finger 1
increases expression
ISO
geldanamycin results in increased expression of PYGO1 mRNA
CTD
PMID:26705709
NCBI chr 8:82,546,866...82,565,526
Ensembl chr 8:82,546,848...82,565,523
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Rab3b
RAB3B, member RAS oncogene family
increases expression
ISO
geldanamycin results in increased expression of RAB3B mRNA
CTD
PMID:26705709
NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:128,841,716...128,926,086
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Rabep1
rabaptin, RAB GTPase binding effector protein 1
increases expression
ISO
geldanamycin results in increased expression of RABEP1 mRNA
CTD
PMID:26705709
NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177
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Raf1
Raf-1 proto-oncogene, serine/threonine kinase
increases expression decreases expression multiple interactions
ISO
geldanamycin results in increased expression of RAF1 protein geldanamycin results in decreased expression of RAF1 protein geldanamycin results in decreased expression of and results in decreased phosphorylation of RAF1 protein
CTD
PMID:8816498 PMID:19167484 PMID:24450340
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813
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Rapgef2
Rap guanine nucleotide exchange factor 2
increases expression
ISO
geldanamycin results in increased expression of RAPGEF2 mRNA
CTD
PMID:26705709
NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:166,505,868...166,726,698
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Rassf8
Ras association domain family member 8
increases expression
ISO
geldanamycin results in increased expression of RASSF8 mRNA
CTD
PMID:26705709
NCBI chr 4:180,447,050...180,528,792
Ensembl chr 4:180,446,846...180,528,790
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Rbak
RB-associated KRAB zinc finger
increases expression
ISO
geldanamycin results in increased expression of RBAK mRNA
CTD
PMID:26705709
NCBI chr12:16,488,895...16,502,523
Ensembl chr12:16,488,950...16,502,733
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Rbm26
RNA binding motif protein 26
increases expression
ISO
geldanamycin results in increased expression of RBM26 mRNA
CTD
PMID:26705709
NCBI chr15:88,299,378...88,379,365
Ensembl chr15:88,301,436...88,378,686
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Rbms3
RNA binding motif, single stranded interacting protein 3
increases expression
ISO
geldanamycin results in increased expression of RBMS3 mRNA
CTD
PMID:26705709
NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:125,183,315...126,503,586
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Rcan1
regulator of calcineurin 1
increases expression
ISO
geldanamycin results in increased expression of RCAN1 mRNA
CTD
PMID:26705709
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
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Rdh10
retinol dehydrogenase 10
increases expression
ISO
geldanamycin results in increased expression of RDH10 mRNA
CTD
PMID:26705709
NCBI chr 5:7,969,931...7,998,834
Ensembl chr 5:7,971,705...7,999,019
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
geldanamycin inhibits the reaction [TNF protein affects the localization of RELA protein]; geldanamycin inhibits the reaction [TNF protein results in increased expression of RELA mRNA]
CTD
PMID:37586545
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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Resf1
retroelement silencing factor 1
increases expression
ISO
geldanamycin results in increased expression of KIAA1551 mRNA
CTD
PMID:26705709
NCBI chr 4:184,057,165...184,093,374
Ensembl chr 4:184,057,010...184,098,429
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Rfx7
regulatory factor X, 7
increases expression
ISO
geldanamycin results in increased expression of RFX7 mRNA
CTD
PMID:26705709
NCBI chr 8:82,134,747...82,219,898
Ensembl chr 8:82,134,747...82,219,898
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Rngtt
RNA guanylyltransferase and 5'-phosphatase
increases expression decreases expression
ISO
geldanamycin results in increased expression of RNGTT mRNA geldanamycin results in decreased expression of RNGTT protein
CTD
PMID:26705709 PMID:30166341
NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:52,503,313...52,709,597
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Ro60
Ro60, Y RNA binding protein
increases expression
ISO
geldanamycin results in increased expression of TROVE2 mRNA
CTD
PMID:26705709
NCBI chr13:58,049,838...58,070,828
Ensembl chr13:58,049,858...58,076,264
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Rock2
Rho-associated coiled-coil containing protein kinase 2
increases expression
ISO
geldanamycin results in increased expression of ROCK2 mRNA
CTD
PMID:26705709
NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:45,407,965...45,502,771
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Rplp0
ribosomal protein lateral stalk subunit P0
decreases expression
ISO
geldanamycin results in decreased expression of RPLP0 mRNA
CTD
PMID:30166341
NCBI chr12:46,715,121...46,718,390
Ensembl chr12:46,715,124...46,718,422
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Rttn
rotatin
increases expression
ISO
geldanamycin results in increased expression of RTTN mRNA
CTD
PMID:26705709
NCBI chr18:84,495,813...84,673,079
Ensembl chr18:84,482,601...84,700,463
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Rufy2
RUN and FYVE domain containing 2
increases expression
ISO
geldanamycin results in increased expression of RUFY2 mRNA
CTD
PMID:26705709
NCBI chr20:25,566,950...25,657,937
Ensembl chr20:25,621,646...25,656,844
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S100a4
S100 calcium-binding protein A4
decreases expression
ISO
geldanamycin results in decreased expression of S100A4 mRNA
CTD
PMID:26705709
NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837
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Samd5
sterile alpha motif domain containing 5
increases expression
ISO
geldanamycin results in increased expression of SAMD5 mRNA
CTD
PMID:26705709
NCBI chr 1:5,861,793...5,911,153
Ensembl chr 1:5,497,567...5,911,064
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Sar1b
secretion associated, Ras related GTPase 1B
increases expression
ISO
geldanamycin results in increased expression of SAR1B mRNA
CTD
PMID:26705709
NCBI chr10:36,525,365...36,555,009
Ensembl chr10:36,519,384...36,555,005
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Scrn3
secernin 3
increases expression
ISO
geldanamycin results in increased expression of SCRN3 mRNA
CTD
PMID:26705709
NCBI chr 3:78,596,330...78,621,132
Ensembl chr 3:78,596,386...78,621,132
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Scyl2
SCY1 like pseudokinase 2
increases expression
ISO
geldanamycin results in increased expression of SCYL2 mRNA
CTD
PMID:26705709
NCBI chr 7:25,951,734...26,004,663
Ensembl chr 7:25,945,258...26,004,631
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Sema3d
semaphorin 3D
increases expression
ISO
geldanamycin results in increased expression of SEMA3D mRNA
CTD
PMID:26705709
NCBI chr 4:23,271,815...23,460,971
Ensembl chr 4:23,271,825...23,460,971
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Senp1
SUMO specific peptidase 1
increases expression
ISO
geldanamycin results in increased expression of SENP1 mRNA
CTD
PMID:26705709
NCBI chr 7:131,042,237...131,105,826
Ensembl chr 7:131,044,818...131,100,851
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Serpine1
serpin family E member 1
increases expression
ISO
geldanamycin results in increased expression of SERPINE1 mRNA
CTD
PMID:26705709
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
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Sesn3
sestrin 3
increases expression
ISO
geldanamycin results in increased expression of SESN3 mRNA
CTD
PMID:26705709
NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:19,415,347...19,466,904
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Setd2
SET domain containing 2, histone lysine methyltransferase
increases expression
ISO
geldanamycin results in increased expression of SETD2 mRNA
CTD
PMID:26705709
NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863
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Setx
senataxin
increases expression
ISO
geldanamycin results in increased expression of SETX mRNA
CTD
PMID:26705709
NCBI chr 3:32,825,771...32,878,740
Ensembl chr 3:32,828,412...32,878,740
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Sfpq
splicing factor proline and glutamine rich
increases expression
ISO
geldanamycin results in increased expression of SFPQ mRNA
CTD
PMID:26705709
NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926
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Sgms2
sphingomyelin synthase 2
increases expression
ISO
geldanamycin results in increased expression of SGMS2 mRNA
CTD
PMID:26705709
NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:222,567,664...222,590,807
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Sike1
suppressor of IKBKE 1
increases expression
ISO
geldanamycin results in increased expression of SIKE1 mRNA
CTD
PMID:26705709
NCBI chr 2:193,206,490...193,214,321
Ensembl chr 2:193,206,490...193,217,004
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Skic3
SKI3 subunit of superkiller complex
increases expression
ISO
geldanamycin results in increased expression of SKIC3 mRNA
CTD
PMID:26705709
NCBI chr 2:7,363,417...7,526,351
Ensembl chr 2:7,363,535...7,483,496
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Slain2
SLAIN motif family, member 2
increases expression
ISO
geldanamycin results in increased expression of SLAIN2 mRNA
CTD
PMID:26705709
NCBI chr14:35,590,050...35,667,734
Ensembl chr14:35,590,057...35,658,684
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Slc16a1
solute carrier family 16 member 1
increases expression
ISO
geldanamycin results in increased expression of SLC16A1 mRNA
CTD
PMID:26705709
NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
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Slc16a7
solute carrier family 16 member 7
increases expression
ISO
geldanamycin results in increased expression of SLC16A7 mRNA
CTD
PMID:26705709
NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386
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Slc2a13
solute carrier family 2 member 13
increases expression
ISO
geldanamycin results in increased expression of SLC2A13 mRNA
CTD
PMID:26705709
NCBI chr 7:124,278,881...124,606,146
Ensembl chr 7:124,278,882...124,606,146
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Slc38a1
solute carrier family 38, member 1
increases expression
ISO
geldanamycin results in increased expression of SLC38A1 mRNA
CTD
PMID:26705709
NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:129,617,387...129,681,778
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Slc39a6
solute carrier family 39 member 6
increases expression
ISO
geldanamycin results in increased expression of SLC39A6 mRNA
CTD
PMID:26705709
NCBI chr18:16,139,621...16,160,163
Ensembl chr18:16,135,008...16,160,163
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Slc8a1
solute carrier family 8 member A1
increases expression
ISO
geldanamycin results in increased expression of SLC8A1 mRNA
CTD
PMID:26705709
NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964
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Slfn5
schlafen family member 5
increases expression
ISO
geldanamycin results in increased expression of SLFN5 mRNA
CTD
PMID:26705709
NCBI chr10:68,378,440...68,392,515
Ensembl chr10:68,378,449...68,392,544
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Smarca2
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
increases expression
ISO
geldanamycin results in increased expression of SMARCA2 mRNA
CTD
PMID:26705709
NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:233,617,366...233,784,869
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Smc1a
structural maintenance of chromosomes 1A
increases expression
ISO
geldanamycin results in increased expression of SMC1A mRNA
CTD
PMID:26705709
NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462
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Smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
increases expression
ISO
geldanamycin results in increased expression of SMCHD1 mRNA
CTD
PMID:26705709
NCBI chr 9:118,690,050...118,837,281
Ensembl chr 9:118,690,057...118,833,452
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Sos2
SOS Ras/Rho guanine nucleotide exchange factor 2
increases expression
ISO
geldanamycin results in increased expression of SOS2 mRNA
CTD
PMID:26705709
NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:93,778,971...93,892,811
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Sp4
Sp4 transcription factor
increases expression
ISO
geldanamycin results in increased expression of SP4 mRNA
CTD
PMID:26705709
NCBI chr 6:145,330,416...145,395,750
Ensembl chr 6:145,330,416...145,395,146
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Sptbn1
spectrin, beta, non-erythrocytic 1
increases expression
ISO
geldanamycin results in increased expression of SPTBN1 mRNA
CTD
PMID:26705709
NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
multiple interactions
ISO EXP
geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of SRC protein] geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of SRC protein]
CTD
PMID:10401681 PMID:17223712
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
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Srpra
SRP receptor subunit alpha
increases expression
ISO
geldanamycin results in increased expression of SRPRA mRNA
CTD
PMID:26705709
NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:41,818,229...41,824,280
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Srrm2
serine/arginine repetitive matrix 2
increases expression
ISO
geldanamycin results in increased expression of SRRM2 mRNA
CTD
PMID:26705709
NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337
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Srrt
serrate, RNA effector molecule
increases expression
ISO
geldanamycin results in increased expression of SRRT mRNA
CTD
PMID:26705709
NCBI chr12:25,027,883...25,042,847
Ensembl chr12:25,029,334...25,042,845
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Stk11
serine/threonine kinase 11
multiple interactions
ISO
Bortezomib inhibits the reaction [geldanamycin results in decreased expression of and results in decreased phosphorylation of STK11 protein]; geldanamycin results in decreased expression of and results in decreased phosphorylation of STK11 protein
CTD
PMID:37481222
NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965
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Strn4
striatin 4
decreases expression
ISO
geldanamycin results in decreased expression of STRN4 mRNA
CTD
PMID:30166341
NCBI chr 1:86,614,193...86,639,959
Ensembl chr 1:86,610,210...86,639,955
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Stub1
STIP1 homology and U-box containing protein 1
multiple interactions
ISO
geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin promotes the reaction [ESR1 protein binds to STUB1 protein]; STUB1 protein promotes the reaction [geldanamycin results in increased degradation of ESR1 protein]
CTD
PMID:16037132 PMID:25645596
NCBI chr10:15,355,278...15,357,559
Ensembl chr10:15,355,279...15,357,559
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Supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
increases expression
ISO
geldanamycin results in increased expression of SUPT16H mRNA
CTD
PMID:26705709
NCBI chr15:27,341,196...27,378,314
Ensembl chr15:27,341,196...27,378,314
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Tead1
TEA domain transcription factor 1
increases expression
ISO
geldanamycin results in increased expression of TEAD1 mRNA
CTD
PMID:26705709
NCBI chr 1:176,227,175...176,445,122
Ensembl chr 1:176,227,175...176,438,198
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Tet2
tet methylcytosine dioxygenase 2
increases expression
ISO
geldanamycin results in increased expression of TET2 mRNA
CTD
PMID:26705709
NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:224,662,654...224,746,186
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Tfpi
tissue factor pathway inhibitor
increases expression
ISO
geldanamycin results in increased expression of TFPI mRNA
CTD
PMID:26705709
NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742
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Tgfb2
transforming growth factor, beta 2
increases expression
ISO
geldanamycin results in increased expression of TGFB2 mRNA
CTD
PMID:26705709
NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856
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Thbs1
thrombospondin 1
increases expression
ISO
geldanamycin results in increased expression of THBS1 mRNA
CTD
PMID:26705709
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
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Tle4
TLE family member 4, transcriptional corepressor
increases expression
ISO
geldanamycin results in increased expression of TLE4 mRNA
CTD
PMID:26705709
NCBI chr 1:221,086,250...221,222,826
Ensembl chr 1:221,086,253...221,222,826
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Tlk1
tousled-like kinase 1
increases expression
ISO
geldanamycin results in increased expression of TLK1 mRNA
CTD
PMID:26705709
NCBI chr 3:75,928,303...76,035,246
Ensembl chr 3:75,928,303...76,035,059
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Tll1
tolloid-like 1
increases expression
ISO
geldanamycin results in increased expression of TLL1 mRNA
CTD
PMID:26705709
NCBI chr16:30,275,492...30,476,673
Ensembl chr16:30,275,492...30,475,886
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Tlr4
toll-like receptor 4
increases expression
ISO
geldanamycin results in increased expression of TLR4 mRNA
CTD
PMID:26705709
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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Tmem33
transmembrane protein 33
increases expression
ISO
geldanamycin results in increased expression of TMEM33 mRNA
CTD
PMID:26705709
NCBI chr14:41,242,358...41,264,586
Ensembl chr14:41,242,358...41,264,586
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Tmod3
tropomodulin 3
increases expression
ISO
geldanamycin results in increased expression of TMOD3 mRNA
CTD
PMID:26705709
NCBI chr 8:85,131,295...85,191,477
Ensembl chr 8:85,131,299...85,191,341
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Tmtc3
transmembrane O-mannosyltransferase targeting cadherins 3
increases expression
ISO
geldanamycin results in increased expression of TMTC3 mRNA
CTD
PMID:26705709
NCBI chr 7:37,151,456...37,196,550
Ensembl chr 7:37,151,456...37,196,540
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Tnf
tumor necrosis factor
multiple interactions
ISO
geldanamycin inhibits the reaction [TNF protein affects the localization of RELA protein]; geldanamycin inhibits the reaction [TNF protein results in increased expression of ABCB1 mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; geldanamycin inhibits the reaction [TNF protein results in increased expression of EGFR mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of HIF1A mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of RELA mRNA] geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]
CTD
PMID:11472980 PMID:12571865 PMID:37586545
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfsf15
TNF superfamily member 15
decreases expression
ISO
geldanamycin results in decreased expression of TNFSF15 mRNA
CTD
PMID:26705709
NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882
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Tnks2
tankyrase 2
increases expression
ISO
geldanamycin results in increased expression of TNKS2 mRNA
CTD
PMID:26705709
NCBI chr 1:243,980,432...244,033,629
Ensembl chr 1:243,980,414...244,033,634
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Tob2
transducer of ERBB2, 2
increases expression
ISO
geldanamycin results in increased expression of TOB2 mRNA
CTD
PMID:26705709
NCBI chr 7:115,242,843...115,251,563
Ensembl chr 7:115,239,895...115,258,155
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Tp53
tumor protein p53
affects localization affects expression multiple interactions
ISO
geldanamycin affects the localization of TP53 protein geldanamycin affects the expression of TP53 protein Tretinoin inhibits the reaction [geldanamycin affects the localization of TP53 protein]
CTD
PMID:17293044 PMID:24211270
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tp53bp1
tumor protein p53 binding protein 1
increases expression
ISO
geldanamycin results in increased expression of TP53BP1 mRNA
CTD
PMID:26705709
NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
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Tpm4
tropomyosin 4
increases expression
ISO
geldanamycin results in increased expression of TPM4 mRNA
CTD
PMID:26705709
NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494
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Tpp2
tripeptidyl peptidase 2
increases expression
ISO
geldanamycin results in increased expression of TPP2 mRNA
CTD
PMID:26705709
NCBI chr 9:53,538,788...53,620,253
Ensembl chr 9:53,538,313...53,620,251
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Tpr
translocated promoter region, nuclear basket protein
increases expression
ISO
geldanamycin results in increased expression of TPR mRNA
CTD
PMID:26705709
NCBI chr13:64,974,419...65,037,604
Ensembl chr13:64,974,419...65,037,602
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Trim59
tripartite motif-containing 59
increases expression
ISO
geldanamycin results in increased expression of TRIM59 mRNA
CTD
PMID:26705709
NCBI chr 2:155,579,183...155,593,450
Ensembl chr 2:155,567,115...155,598,645
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Trpc6
transient receptor potential cation channel, subfamily C, member 6
increases expression
ISO
geldanamycin results in increased expression of TRPC6 mRNA
CTD
PMID:26705709
NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
geldanamycin affects the reaction [Capsaicin results in increased activity of TRPV1]
CTD
PMID:11930156
NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021
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Ttc3
tetratricopeptide repeat domain 3
increases expression
ISO
geldanamycin results in increased expression of TTC3 mRNA
CTD
PMID:26705709
NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418
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Tuba1a
tubulin, alpha 1A
decreases expression
ISO
geldanamycin results in decreased expression of TUBA1A mRNA
CTD
PMID:27015953
NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035
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Ube2h
ubiquitin-conjugating enzyme E2H
increases expression
ISO
geldanamycin results in increased expression of UBE2H mRNA
CTD
PMID:26705709
NCBI chr 4:59,802,102...59,897,583
Ensembl chr 4:59,802,102...59,897,583
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Ubn2
ubinuclein 2
increases expression
ISO
geldanamycin results in increased expression of UBN2 mRNA
CTD
PMID:26705709
NCBI chr 4:68,130,497...68,218,471
Ensembl chr 4:68,133,261...68,197,402
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Ugcg
UDP-glucose ceramide glucosyltransferase
increases expression
ISO
geldanamycin results in increased expression of UGCG mRNA
CTD
PMID:26705709
NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417
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Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
increases expression
ISO
geldanamycin results in increased expression of UGGT1 mRNA
CTD
PMID:26705709
NCBI chr 9:45,851,127...45,964,454
Ensembl chr 9:45,854,985...45,964,455
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Uhmk1
U2AF homology motif kinase 1
increases expression
ISO
geldanamycin results in increased expression of UHMK1 mRNA
CTD
PMID:26705709
NCBI chr13:84,929,418...84,949,194
Ensembl chr13:84,922,829...84,949,061
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Usp10
ubiquitin specific peptidase 10
increases expression
ISO
geldanamycin results in increased expression of USP10 mRNA
CTD
PMID:26705709
NCBI chr19:64,881,255...64,923,522
Ensembl chr19:64,881,315...64,923,519
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Usp12
ubiquitin specific peptidase 12
increases expression
ISO
geldanamycin results in increased expression of USP12 mRNA
CTD
PMID:26705709
NCBI chr12:13,423,625...13,477,547
Ensembl chr12:13,422,427...13,477,547
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Usp25
ubiquitin specific peptidase 25
increases expression
ISO
geldanamycin results in increased expression of USP25 mRNA
CTD
PMID:26705709
NCBI chr11:29,088,283...29,198,323
Ensembl chr11:29,087,736...29,198,323
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Usp36
ubiquitin specific peptidase 36
increases expression
ISO
geldanamycin results in increased expression of USP36 mRNA
CTD
PMID:26705709
NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450
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Vapb
VAMP associated protein B and C
increases expression
ISO
geldanamycin results in increased expression of VAPB mRNA
CTD
PMID:26705709
NCBI chr 3:182,954,247...182,997,018
Ensembl chr 3:182,954,240...183,028,619
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Vdac3
voltage-dependent anion channel 3
decreases expression
ISO
geldanamycin results in decreased expression of VDAC3 mRNA
CTD
PMID:30166341
NCBI chr16:76,137,489...76,153,933
Ensembl chr16:76,137,504...76,155,304
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Vldlr
very low density lipoprotein receptor
multiple interactions
EXP
geldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein]
CTD
PMID:15808840
NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:234,240,121...234,272,154
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Vmp1
vacuole membrane protein 1
increases expression
ISO
geldanamycin results in increased expression of VMP1 mRNA
CTD
PMID:26705709
NCBI chr10:71,903,223...72,002,337
Ensembl chr10:71,903,227...72,002,319
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Vps50
VPS50 subunit of EARP/GARPII complex
increases expression
ISO
geldanamycin results in increased expression of VPS50 mRNA
CTD
PMID:26705709
NCBI chr 4:32,439,101...32,540,299
Ensembl chr 4:32,439,138...32,540,538
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Zbed6
zinc finger, BED-type containing 6
increases expression
ISO
geldanamycin results in increased expression of ZBED6 mRNA
CTD
PMID:26705709
NCBI chr13:47,659,269...47,665,540
Ensembl chr13:47,658,667...47,668,221
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Zc3h11a
zinc finger CCCH-type containing 11A
increases expression
ISO
geldanamycin results in increased expression of ZC3H11A mRNA
CTD
PMID:26705709
NCBI chr13:47,625,444...47,665,971
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Zfhx4
zinc finger homeobox 4
increases expression
ISO
geldanamycin results in increased expression of ZFHX4 mRNA
CTD
PMID:26705709
NCBI chr 2:98,131,996...98,321,070
Ensembl chr 2:98,131,996...98,315,469
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Zfp207
zinc finger protein 207
decreases expression
ISO
geldanamycin results in decreased expression of ZNF207 mRNA
CTD
PMID:30166341
NCBI chr10:65,883,630...65,895,895
Ensembl chr10:65,883,599...65,895,895
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Zfp326
zinc finger protein 326
increases expression
ISO
geldanamycin results in increased expression of ZNF326 mRNA
CTD
PMID:26705709
NCBI chr14:4,246,081...4,286,805
Ensembl chr14:4,245,878...4,331,064
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Zfp518a
zinc finger protein 518A
increases expression
ISO
geldanamycin results in increased expression of ZNF518A mRNA
CTD
PMID:26705709
NCBI chr 1:249,668,815...249,694,401
Ensembl chr 1:249,657,809...249,695,569
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Zfp638
zinc finger protein 638
increases expression
ISO
geldanamycin results in increased expression of ZNF638 mRNA
CTD
PMID:26705709
NCBI chr 4:117,913,528...118,032,644
Ensembl chr 4:117,913,545...118,032,643
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Zfp655
zinc finger protein 655
increases expression
ISO
geldanamycin results in increased expression of ZNF655 mRNA
CTD
PMID:26705709
NCBI chr12:14,466,006...14,489,049
Ensembl chr12:14,471,415...14,488,678
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Zfp704
zinc finger protein 704
increases expression
ISO
geldanamycin results in increased expression of ZNF704 mRNA
CTD
PMID:26705709
NCBI chr 2:94,079,209...94,267,071
Ensembl chr 2:94,079,119...94,256,672
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Zfp711
zinc finger protein 711
increases expression
ISO
geldanamycin results in increased expression of ZNF711 mRNA
CTD
PMID:26705709
NCBI chr X:81,838,483...81,871,767
Ensembl chr X:81,838,620...81,871,784
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Zfp770
zinc finger protein 770
increases expression
ISO
geldanamycin results in increased expression of ZNF770 mRNA
CTD
PMID:26705709
NCBI chr 3:121,417,723...121,425,956
Ensembl chr 3:121,417,250...121,422,153
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Zfr
zinc finger RNA binding protein
increases expression
ISO
geldanamycin results in increased expression of ZFR mRNA
CTD
PMID:26705709
NCBI chr 2:62,864,333...62,927,377
Ensembl chr 2:62,864,338...62,929,133
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Zfx
zinc finger protein X-linked
increases expression
ISO
geldanamycin results in increased expression of ZFX mRNA
CTD
PMID:26705709
NCBI chr X:62,798,483...62,847,068
Ensembl chr X:62,798,483...62,875,309
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Zmynd11
zinc finger, MYND-type containing 11
increases expression
ISO
geldanamycin results in increased expression of ZMYND11 mRNA
CTD
PMID:26705709
NCBI chr17:65,226,907...65,323,278
Ensembl chr17:65,234,045...65,323,276
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Znf660
zinc finger protein 660
increases expression
ISO
geldanamycin results in increased expression of ZNF660 mRNA
CTD
PMID:26705709
NCBI chr 8:131,401,672...131,415,046
Ensembl chr 8:131,401,361...131,416,316
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Zxdc
ZXD family zinc finger C
increases expression
ISO
geldanamycin results in increased expression of ZXDC mRNA
CTD
PMID:26705709
NCBI chr 4:124,439,560...124,471,694
Ensembl chr 4:124,439,573...124,471,683
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]
CTD
PMID:36198566
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]
CTD
PMID:36198566
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Casp3
caspase 3
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 mRNA]
CTD
PMID:36198566
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Cat
catalase
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
CTD
PMID:36198566
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
G
Fasn
fatty acid synthase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of FASN protein]
CTD
PMID:29653099
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of G6PD protein]
CTD
PMID:29653099
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of GPT protein]
CTD
PMID:29653099
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
G
Gsr
glutathione-disulfide reductase
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
CTD
PMID:36198566
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
G
Havcr1
hepatitis A virus cellular receptor 1
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of HAVCR1 protein]
CTD
PMID:36198566
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
G
Il1b
interleukin 1 beta
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
CTD
PMID:36198566
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]
CTD
PMID:36198566
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Lcn2
lipocalin 2
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of LCN2 protein]
CTD
PMID:36198566
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
G
Nos2
nitric oxide synthase 2
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
CTD
PMID:36198566
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
CTD
PMID:36198566
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]
CTD
PMID:29653099
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
G
Srebf2
sterol regulatory element binding transcription factor 2
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA]
CTD
PMID:29653099
NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943
G
Tnf
tumor necrosis factor
multiple interactions
EXP
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
CTD
PMID:36198566
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
leupeptin inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]
CTD
PMID:21818627
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
G
Aqp8
aquaporin 8
multiple interactions
EXP
leupeptin inhibits the reaction [Ethinyl Estradiol results in decreased expression of AQP8 protein]
CTD
PMID:17110522
NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
leupeptin inhibits the reaction [Tretinoin results in increased cleavage of BAX protein]
CTD
PMID:16242776
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Casp6
caspase 6
multiple interactions
ISO
leupeptin inhibits the reaction [Estradiol results in increased degradation of and results in decreased activity of CASP6 protein]
CTD
PMID:15086513
NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726
G
Cdc25c
cell division cycle 25C
multiple interactions increases expression
ISO
leupeptin inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] leupeptin results in increased expression of CDC25C protein
CTD
PMID:29074359
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
G
Cdh1
cadherin 1
multiple interactions
EXP
leupeptin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased degradation of CDH1 protein]
CTD
PMID:19464575
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
G
Cip2a
cellular inhibitor of PP2A
multiple interactions
ISO
leupeptin inhibits the reaction [temsirolimus results in decreased expression of CIP2A protein]
CTD
PMID:24493623
NCBI chr11:65,255,123...65,285,914
Ensembl chr11:65,255,123...65,285,914
G
Ctnnb1
catenin beta 1
multiple interactions
EXP
leupeptin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased degradation of CTNNB1 protein]
CTD
PMID:19464575
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
G
Ctsb
cathepsin B
multiple interactions
ISO
leupeptin inhibits the reaction [CTSB protein results in increased degradation of NEFL protein]
CTD
PMID:11071371
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]
CTD
PMID:9143349
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
G
Ddx3x
DEAD-box helicase 3, X-linked
multiple interactions
ISO
leupeptin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of DDX3X protein]
CTD
PMID:30821613
NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983
G
Egf
epidermal growth factor
decreases degradation
ISO
leupeptin results in decreased degradation of EGF protein
CTD
PMID:23125191
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
G
Eif4a1
eukaryotic translation initiation factor 4A1
multiple interactions
ISO
leupeptin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of EIF4A1 protein]
CTD
PMID:30821613
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
G
Eif4h
eukaryotic translation initiation factor 4H
multiple interactions
ISO
leupeptin inhibits the reaction [[quizartinib co-treated with spautin-1] results in increased degradation of EIF4H protein]
CTD
PMID:30821613
NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346
G
Gja1
gap junction protein, alpha 1
multiple interactions
ISO
leupeptin inhibits the reaction [arsenic trioxide results in decreased expression of GJA1 mRNA]
CTD
PMID:17559834
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
Fomepizole inhibits the reaction [leupeptin promotes the reaction [Acetaminophen results in increased activity of GPT protein]]; leupeptin promotes the reaction [Acetaminophen results in increased activity of GPT protein]
CTD
PMID:33458793
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
leupeptin inhibits the reaction [Particulate Matter results in increased secretion of IL1A protein]
CTD
PMID:21818627
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
G
Il6
interleukin 6
multiple interactions
ISO
leupeptin inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]
CTD
PMID:21818627
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Klk8
kallikrein related-peptidase 8
decreases activity
ISO
leupeptin results in decreased activity of KLK8 protein
CTD
PMID:16800733
NCBI chr 1:103,388,352...103,395,195
Ensembl chr 1:103,388,352...103,395,195
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
leupeptin promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]
CTD
PMID:33458793
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
G
Mt1a
metallothionein 1A
multiple interactions
ISO
leupeptin inhibits the reaction [MT1A protein results in decreased expression of XAF1 protein]; leupeptin inhibits the reaction [XAF1 protein results in decreased expression of MT1A protein]
CTD
PMID:28507149
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
G
Mt2
metallothionein 2
multiple interactions
ISO
leupeptin inhibits the reaction [MT2A protein results in decreased expression of XAF1 protein]; leupeptin inhibits the reaction [XAF1 protein results in decreased expression of MT2A protein]
CTD
PMID:28507149
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
G
Nefl
neurofilament light chain
multiple interactions
ISO
leupeptin inhibits the reaction [CTSB protein results in increased degradation of NEFL protein]
CTD
PMID:11071371
NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515
G
Plin1
perilipin 1
multiple interactions decreases degradation
ISO
leupeptin inhibits the reaction [Nelfinavir results in increased degradation of PLIN1 protein] leupeptin results in decreased degradation of PLIN1 protein
CTD
PMID:17488708
NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206
G
Tgfbr1
transforming growth factor, beta receptor 1
increases expression
EXP
leupeptin results in increased expression of TGFBR1 protein
CTD
PMID:27826032
NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260
G
Xaf1
XIAP associated factor 1
multiple interactions
ISO
leupeptin inhibits the reaction [MT1A protein results in decreased expression of XAF1 protein]; leupeptin inhibits the reaction [MT2A protein results in decreased expression of XAF1 protein]; leupeptin inhibits the reaction [XAF1 protein results in decreased expression of MT1A protein]; leupeptin inhibits the reaction [XAF1 protein results in decreased expression of MT2A protein]
CTD
PMID:28507149
NCBI chr10:57,415,935...57,428,348
Ensembl chr10:57,415,658...57,428,349
G
Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
calpain inhibitor III inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]
CTD
PMID:16891617
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
multiple interactions
EXP
calpain inhibitor III inhibits the reaction [Isoflurane results in increased cleavage of and affects the localization of AIFM1 protein]
CTD
PMID:29289695
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
G
Capn1
calpain 1
multiple interactions decreases activity
ISO EXP
calpain inhibitor III inhibits the reaction [CAPN1 protein results in increased susceptibility to Cisplatin] calpain inhibitor III results in decreased activity of CAPN1 protein calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Manganese results in increased activity of CAPN1 protein]
CTD
PMID:13678654 PMID:20878076 PMID:21985864 PMID:29289695
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
G
Capn2
calpain 2
multiple interactions
EXP
calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein]
CTD
PMID:29289695
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
calpain inhibitor III inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD
PMID:16891617
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]
CTD
PMID:19336499
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Il1a
interleukin 1 alpha
affects localization
ISO
calpain inhibitor III affects the localization of IL1A protein
CTD
PMID:24024155
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
G
Nefl
neurofilament light chain
multiple interactions
EXP
calpain inhibitor III inhibits the reaction [Zymosan results in increased degradation of NEFL protein]
CTD
PMID:15275793
NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
calpain inhibitor III inhibits the reaction [Thioacetamide results in increased expression of NOS2 mRNA]
CTD
PMID:15316131
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
G
Sptan1
spectrin, alpha, non-erythrocytic 1
multiple interactions
ISO EXP
calpain inhibitor III inhibits the reaction [lactacystin results in increased cleavage of SPTAN1 protein] calpain inhibitor III inhibits the reaction [Manganese results in increased cleavage of SPTAN1 protein]
CTD
PMID:21683092 PMID:21985864
NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889
G
Tnf
tumor necrosis factor
multiple interactions
ISO
calpain inhibitor III inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA]
CTD
PMID:15316131
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
A2m
alpha-2-macroglobulin
affects expression
ISO
Vitamin K 3 affects the expression of A2M mRNA
CTD
PMID:20044591
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
G
Abcb11
ATP binding cassette subfamily B member 11
decreases expression
ISO
Vitamin K 3 results in decreased expression of ABCB11 mRNA
CTD
PMID:34767876
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
G
Abcb7
ATP binding cassette subfamily B member 7
affects expression
ISO
Vitamin K 3 affects the expression of ABCB7 mRNA
CTD
PMID:20044591
NCBI chr X:73,361,296...73,502,464
Ensembl chr X:73,361,310...73,502,547
G
Abcc3
ATP binding cassette subfamily C member 3
affects expression
ISO
Vitamin K 3 affects the expression of ABCC3 mRNA
CTD
PMID:20044591
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
G
Abcd4
ATP binding cassette subfamily D member 4
decreases expression
ISO
Vitamin K 3 results in decreased expression of ABCD4 mRNA
CTD
PMID:25270620
NCBI chr 6:109,977,541...109,992,050
Ensembl chr 6:109,977,550...109,991,983
G
Abcg2
ATP binding cassette subfamily G member 2
affects expression
ISO
Vitamin K 3 affects the expression of ABCG2 mRNA
CTD
PMID:20044591
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
G
Abhd14b
abhydrolase domain containing 14b
affects expression
ISO
Vitamin K 3 affects the expression of ABHD14B mRNA
CTD
PMID:20044591
NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
G
Abhd4
abhydrolase domain containing 4, N-acyl phospholipase B
increases expression
ISO
Vitamin K 3 results in increased expression of ABHD4 mRNA
CTD
PMID:25270620
NCBI chr15:31,674,090...31,686,051
Ensembl chr15:31,674,143...31,687,007
G
Abhd5
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of ABHD5 mRNA
CTD
PMID:20044591
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
G
Abr
ABR activator of RhoGEF and GTPase
affects expression
ISO
Vitamin K 3 affects the expression of ABR mRNA
CTD
PMID:20044591
NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467
G
Acat2
acetyl-CoA acetyltransferase 2
affects expression
ISO
Vitamin K 3 affects the expression of ACAT2 mRNA
CTD
PMID:20044591
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
G
Aco1
aconitase 1
affects activity
ISO
Vitamin K 3 affects the activity of ACO1 protein
CTD
PMID:10037708
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
G
Aco2
aconitase 2
affects expression
ISO
Vitamin K 3 affects the expression of ACO2 mRNA
CTD
PMID:20044591
NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
G
Acot13
acyl-CoA thioesterase 13
affects expression
ISO
Vitamin K 3 affects the expression of ACOT13 mRNA
CTD
PMID:20044591
NCBI chr17:40,668,404...40,680,876
Ensembl chr17:40,668,316...40,680,876
G
Acsl1
acyl-CoA synthetase long-chain family member 1
affects expression
ISO
Vitamin K 3 affects the expression of ACSL1 mRNA
CTD
PMID:20044591
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
G
Acss1
acyl-CoA synthetase short-chain family member 1
affects expression
ISO
Vitamin K 3 affects the expression of ACSS1 mRNA
CTD
PMID:20044591
NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748
G
Actr3b
actin related protein 3B
affects expression
ISO
Vitamin K 3 affects the expression of ACTR3B mRNA
CTD
PMID:20044591
NCBI chr 4:9,995,553...10,089,422
Ensembl chr 4:9,996,155...10,089,553
G
Adam19
ADAM metallopeptidase domain 19
decreases expression
ISO
Vitamin K 3 results in decreased expression of ADAM19 mRNA
CTD
PMID:25270620
NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455
G
Adam9
ADAM metallopeptidase domain 9
affects expression
ISO
Vitamin K 3 affects the expression of ADAM9 mRNA
CTD
PMID:23410634
NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646
G
Adcy3
adenylate cyclase 3
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of ADCY3 mRNA Vitamin K 3 results in decreased expression of ADCY3 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173
G
Add3
adducin 3
affects expression
ISO
Vitamin K 3 affects the expression of ADD3 mRNA
CTD
PMID:20044591
NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504
G
Adgra3
adhesion G protein-coupled receptor A3
affects expression
ISO
Vitamin K 3 affects the expression of ADGRA3 mRNA
CTD
PMID:20044591
NCBI chr14:65,085,418...65,188,949
Ensembl chr14:65,087,380...65,188,959
G
Adgrv1
adhesion G protein-coupled receptor V1
affects expression
ISO
Vitamin K 3 affects the expression of ADGRV1 mRNA
CTD
PMID:20044591
NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372
G
Adk
adenosine kinase
affects expression
ISO
Vitamin K 3 affects the expression of ADK mRNA
CTD
PMID:20044591
NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745
G
Ago1
argonaute RISC component 1
affects expression
ISO
Vitamin K 3 affects the expression of AGO1 mRNA
CTD
PMID:20044591
NCBI chr 5:144,006,618...144,064,740
Ensembl chr 5:144,006,618...144,041,624
G
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
affects expression
ISO
Vitamin K 3 affects the expression of AGPAT3 mRNA
CTD
PMID:20044591
NCBI chr20:10,330,650...10,415,026
Ensembl chr20:10,394,465...10,410,632
G
Agr2
anterior gradient 2, protein disulphide isomerase family member
affects expression
ISO
Vitamin K 3 affects the expression of AGR2 mRNA
CTD
PMID:20044591
NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677
G
Ahr
aryl hydrocarbon receptor
affects expression
ISO
Vitamin K 3 affects the expression of AHR mRNA
CTD
PMID:20044591
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
G
Aire
autoimmune regulator
decreases expression
ISO
Vitamin K 3 results in decreased expression of AIRE mRNA
CTD
PMID:25270620
NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,635,775...10,650,709
G
Akap12
A-kinase anchoring protein 12
affects expression
ISO
Vitamin K 3 affects the expression of AKAP12 mRNA
CTD
PMID:23410634
NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557
G
Akap9
A-kinase anchoring protein 9
affects expression
ISO
Vitamin K 3 affects the expression of AKAP9 mRNA
CTD
PMID:20044591
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
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Akip1
A-kinase interacting protein 1
affects expression
ISO
Vitamin K 3 affects the expression of AKIP1 mRNA
CTD
PMID:20044591
NCBI chr 1:173,169,520...173,178,445
Ensembl chr 1:173,169,458...173,178,445
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Vitamin K 3 results in increased expression of AKR1B10 mRNA
CTD
PMID:23410634 PMID:34767876
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
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Akr1c1
aldo-keto reductase family 1, member C1
affects expression
ISO
Vitamin K 3 affects the expression of AKR1C1 mRNA
CTD
PMID:20044591
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Vitamin K 3 results in increased expression of AKR1C2 mRNA
CTD
PMID:12414654 PMID:23410634
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
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Akr7a2
aldo-keto reductase family 7, member A2
multiple interactions increases metabolic processing decreases response to substance
ISO
AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione]; AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species] AKR7A5 protein results in increased metabolism of Vitamin K 3 AKR7A2 protein results in decreased susceptibility to Vitamin K 3
CTD
PMID:22001351 PMID:24590062
NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
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Alb
albumin
affects expression
ISO
Vitamin K 3 affects the expression of ALB mRNA
CTD
PMID:20044591
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Aldh18a1
aldehyde dehydrogenase 18 family, member A1
affects expression
ISO
Vitamin K 3 affects the expression of ALDH18A1 mRNA
CTD
PMID:20044591
NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
ISO
Vitamin K 3 affects the expression of ALDH1A1 mRNA
CTD
PMID:23410634
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
affects expression
ISO
Vitamin K 3 affects the expression of ALDH1A3 mRNA
CTD
PMID:20829426
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
ISO
Vitamin K 3 affects the expression of ALDH2 mRNA
CTD
PMID:20044591
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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Aldh3b1
aldehyde dehydrogenase 3 family, member B1
decreases response to substance
ISO
ALDH3B1 protein results in decreased susceptibility to Vitamin K 3
CTD
PMID:20699116
NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
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Aldh6a1
aldehyde dehydrogenase 6 family, member A1
affects expression
ISO
Vitamin K 3 affects the expression of ALDH6A1 mRNA
CTD
PMID:20044591
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743
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Alpl
alkaline phosphatase, biomineralization associated
decreases secretion
ISO
Vitamin K 3 results in decreased secretion of ALPL protein
CTD
PMID:30453296
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
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Alyref
Aly/REF export factor
affects expression
ISO
Vitamin K 3 affects the expression of ALYREF mRNA
CTD
PMID:20044591
NCBI chr10:106,369,750...106,373,395
Ensembl chr10:106,369,750...106,373,395
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Amotl2
angiomotin like 2
affects expression
ISO
Vitamin K 3 affects the expression of AMOTL2 mRNA
CTD
PMID:20044591
NCBI chr 8:112,182,060...112,198,032
Ensembl chr 8:112,181,863...112,198,030
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Anapc1
anaphase promoting complex subunit 1
affects expression
ISO
Vitamin K 3 affects the expression of ANAPC1 mRNA
CTD
PMID:20044591
NCBI chr 3:136,303,350...136,383,464
Ensembl chr 3:136,303,413...136,383,464
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Ang
angiogenin
affects expression
ISO
Vitamin K 3 affects the expression of ANG mRNA
CTD
PMID:20044591
NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106
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Ank3
ankyrin 3
affects expression
ISO
Vitamin K 3 affects the expression of ANK3 mRNA
CTD
PMID:20044591
NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
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Ankra2
ankyrin repeat family A member 2
affects expression
ISO
Vitamin K 3 affects the expression of ANKRA2 mRNA
CTD
PMID:23410634
NCBI chr 2:31,347,158...31,358,002
Ensembl chr 2:31,347,090...31,364,394
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Ankrd11
ankyrin repeat domain containing 11
affects expression
ISO
Vitamin K 3 affects the expression of ANKRD11 mRNA
CTD
PMID:20044591
NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491
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Ankrd37
ankyrin repeat domain 37
decreases expression
ISO
Vitamin K 3 results in decreased expression of ANKRD37 mRNA
CTD
PMID:25270620
NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545
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Anks1a
ankyrin repeat and sterile alpha motif domain containing 1A
affects expression
ISO
Vitamin K 3 affects the expression of ANKS1 mRNA
CTD
PMID:20044591
NCBI chr20:5,965,421...6,118,875
Ensembl chr20:5,965,028...6,118,875
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Anks6
ankyrin repeat and sterile alpha motif domain containing 6
affects expression
ISO
Vitamin K 3 affects the expression of ANKS6 mRNA
CTD
PMID:20044591
NCBI chr 5:66,104,770...66,146,186
Ensembl chr 5:66,104,773...66,146,186
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Anp32b
acidic nuclear phosphoprotein 32 family member B
affects expression
ISO
Vitamin K 3 affects the expression of ANP32B mRNA
CTD
PMID:20044591
NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437
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Antkmt
adenine nucleotide translocase lysine methyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of ANTKMT mRNA
CTD
PMID:20044591
NCBI chr10:15,316,797...15,320,950
Ensembl chr10:15,316,772...15,318,656
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Anxa13
annexin A13
affects expression
ISO
Vitamin K 3 affects the expression of ANXA13 mRNA
CTD
PMID:20044591
NCBI chr 7:91,773,844...91,826,386
Ensembl chr 7:91,770,861...91,826,386
G
Aox1
aldehyde oxidase 1
multiple interactions decreases activity
ISO
Vitamin K 3 inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide] Vitamin K 3 results in decreased activity of AOX1 protein
CTD
PMID:20040581
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
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Apbb2
amyloid beta precursor protein binding family B member 2
affects expression
ISO
Vitamin K 3 affects the expression of APBB2 mRNA
CTD
PMID:20044591
NCBI chr14:41,849,638...42,232,930
Ensembl chr14:41,911,785...42,232,280
G
Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
increases response to substance
ISO
APEX1 gene mutant form results in increased susceptibility to Vitamin K 3
CTD
PMID:11454706
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329
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Aplp2
amyloid beta precursor like protein 2
affects expression
ISO
Vitamin K 3 affects the expression of APLP2 mRNA
CTD
PMID:20044591
NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031
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Apoa1
apolipoprotein A1
affects expression
ISO
Vitamin K 3 affects the expression of APOA1 mRNA
CTD
PMID:20829426
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729
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Apoa5
apolipoprotein A5
affects expression
ISO
Vitamin K 3 affects the expression of APOA5 mRNA
CTD
PMID:23410634
NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507
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Apoc3
apolipoprotein C3
affects expression
ISO
Vitamin K 3 affects the expression of APOC3 mRNA
CTD
PMID:20044591
NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679
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Apoe
apolipoprotein E
affects response to substance
ISO
APOE protein affects the susceptibility to Vitamin K 3
CTD
PMID:28728140
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
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Apoh
apolipoprotein H
affects expression
ISO
Vitamin K 3 affects the expression of APOH mRNA
CTD
PMID:20044591
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
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Aqp11
aquaporin 11
affects expression
ISO
Vitamin K 3 affects the expression of AQP11 mRNA
CTD
PMID:20044591
NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:161,457,754...161,467,945
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Areg
amphiregulin
increases expression
ISO
Vitamin K 3 results in increased expression of AREG mRNA
CTD
PMID:12414654
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
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Arg2
arginase 2
affects expression
ISO
Vitamin K 3 affects the expression of ARG2 mRNA
CTD
PMID:23410634
NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375
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Arhgef7
Rho guanine nucleotide exchange factor 7
affects expression
ISO
Vitamin K 3 affects the expression of ARHGEF7 mRNA
CTD
PMID:20044591
NCBI chr16:84,373,123...84,484,759
Ensembl chr16:84,373,123...84,484,597
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Arid3a
AT-rich interaction domain 3A
affects expression
ISO
Vitamin K 3 affects the expression of ARID3A mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 7:10,403,161...10,431,551
Ensembl chr 7:10,405,631...10,427,926
G
Arid5a
AT-rich interaction domain 5A
affects expression
ISO
Vitamin K 3 affects the expression of ARID5A mRNA
CTD
PMID:20044591
NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:46,030,548...46,045,363
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Armcx1
armadillo repeat containing, X-linked 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of ARMCX1 mRNA
CTD
PMID:25270620
NCBI chr X:102,192,225...102,196,130
Ensembl chr X:102,192,015...102,199,115
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Arrdc2
arrestin domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of ARRDC2 mRNA
CTD
PMID:20044591
NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158
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Asf1a
anti-silencing function 1A histone chaperone
increases expression
ISO
Vitamin K 3 results in increased expression of ASF1A mRNA
CTD
PMID:23410634
NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639
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Asic1
acid sensing ion channel subunit 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of ASIC1 mRNA
CTD
PMID:25270620
NCBI chr 7:132,677,158...132,707,379
Ensembl chr 7:132,698,723...132,707,832
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Atf3
activating transcription factor 3
affects expression increases expression
ISO
Vitamin K 3 affects the expression of ATF3 mRNA Vitamin K 3 results in increased expression of ATF3 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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Atf6
activating transcription factor 6
multiple interactions increases expression
ISO
Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein]
CTD
PMID:19819344
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Atg5
autophagy related 5
affects response to substance
EXP ISO
ATG5 mRNA affects the susceptibility to Vitamin K 3 ATG5 protein affects the susceptibility to Vitamin K 3
CTD
PMID:18073215 PMID:18319638 PMID:20578144
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
G
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
affects expression
ISO
Vitamin K 3 affects the expression of ATIC mRNA
CTD
PMID:20044591
NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756
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Atox1
antioxidant 1 copper chaperone
affects expression
ISO
Vitamin K 3 affects the expression of ATOX1 mRNA
CTD
PMID:20044591
NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585
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Atp5if1
ATP synthase inhibitory factor subunit 1
affects expression
ISO
Vitamin K 3 affects the expression of ATP5IF1 mRNA
CTD
PMID:20044591
NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
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Atp5po
ATP synthase peripheral stalk subunit OSCP
affects expression
ISO
Vitamin K 3 affects the expression of ATP5PO mRNA
CTD
PMID:20044591
NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520
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Atp7b
ATPase copper transporting beta
affects expression
ISO
Vitamin K 3 affects the expression of ATP7B mRNA
CTD
PMID:20044591
NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
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Atrn
attractin
affects expression
ISO
Vitamin K 3 affects the expression of ATRN mRNA
CTD
PMID:20044591
NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360
G
Atrx
ATRX, chromatin remodeler
affects expression
ISO
Vitamin K 3 affects the expression of ATRX mRNA
CTD
PMID:20829426
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880
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Atxn2l
ataxin 2-like
affects expression
ISO
Vitamin K 3 affects the expression of ATXN2L mRNA
CTD
PMID:20044591
NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579
G
Auh
AU RNA binding methylglutaconyl-CoA hydratase
affects expression
ISO
Vitamin K 3 affects the expression of AUH mRNA
CTD
PMID:20044591
NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587
G
Aurkb
aurora kinase B
decreases expression
ISO
Vitamin K 3 results in decreased expression of AURKB mRNA
CTD
PMID:12414654
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
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Auts2
activator of transcription and developmental regulator AUTS2
affects expression
ISO
Vitamin K 3 affects the expression of AUTS2 mRNA
CTD
PMID:20044591
NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386
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B3galt6
Beta-1,3-galactosyltransferase 6
affects expression
ISO
Vitamin K 3 affects the expression of B3GALT6 mRNA
CTD
PMID:20044591
NCBI chr 5:171,866,428...171,868,564
Ensembl chr 5:171,864,094...171,874,789
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Bahd1
bromo adjacent homology domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of BAHD1 mRNA
CTD
PMID:20044591
NCBI chr 3:126,341,853...126,368,281
Ensembl chr 3:126,345,371...126,368,278
G
Bak1
BCL2-antagonist/killer 1
affects expression
ISO
Vitamin K 3 affects the expression of BAK1 mRNA
CTD
PMID:20044591
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
G
Bambi
BMP and activin membrane-bound inhibitor
affects expression
ISO
Vitamin K 3 affects the expression of BAMBI mRNA
CTD
PMID:23410634
NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247
G
Batf
basic leucine zipper ATF-like transcription factor
increases expression
ISO
Vitamin K 3 results in increased expression of BATF mRNA
CTD
PMID:25270620
NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052
G
Bax
BCL2 associated X, apoptosis regulator
affects localization increases expression multiple interactions
EXP ISO
Vitamin K 3 affects the localization of BAX protein Vitamin K 3 results in increased expression of BAX protein EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of BAX protein]
CTD
PMID:15961378 PMID:25005833
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bbc3
Bcl-2 binding component 3
affects expression
ISO
Vitamin K 3 affects the expression of BBC3 mRNA
CTD
PMID:20044591
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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Bbs2
Bardet-Biedl syndrome 2
affects expression
ISO
Vitamin K 3 affects the expression of BBS2 mRNA
CTD
PMID:20044591
NCBI chr19:10,915,566...10,950,911
Ensembl chr19:10,915,476...10,950,921
G
Bcar3
BCAR3 adaptor protein, NSP family member
affects expression
ISO
Vitamin K 3 affects the expression of BCAR3 mRNA
CTD
PMID:20044591
NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:213,209,893...213,323,302
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Bcas1
brain enriched myelin associated protein 1
affects expression
ISO
Vitamin K 3 affects the expression of BCAS1 mRNA
CTD
PMID:20044591
NCBI chr 3:179,554,754...179,637,800
Ensembl chr 3:179,551,704...179,637,743
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
ISO EXP
[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein] Vitamin K 3 results in decreased expression of BCL2 mRNA; Vitamin K 3 results in decreased expression of BCL2 protein Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein]
CTD
PMID:19082730 PMID:19265712 PMID:25005833
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bcl6
BCL6, transcription repressor
affects expression
ISO
Vitamin K 3 affects the expression of BCL6 mRNA
CTD
PMID:20044591
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
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Bcl9l
BCL9 like
decreases expression
ISO
Vitamin K 3 results in decreased expression of BCL9L protein
CTD
PMID:31238027
NCBI chr 8:53,708,770...53,738,880
Ensembl chr 8:53,708,770...53,737,395
G
Bdh2
3-hydroxybutyrate dehydrogenase 2
affects expression
ISO
Vitamin K 3 affects the expression of BDH2 mRNA
CTD
PMID:20044591
NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006
G
Becn1
beclin 1
affects expression
ISO
Vitamin K 3 affects the expression of BECN1 mRNA
CTD
PMID:20044591
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
G
Bet1l
Bet1 golgi vesicular membrane trafficking protein-like
affects expression
ISO
Vitamin K 3 affects the expression of BET1L mRNA
CTD
PMID:20044591
NCBI chr 1:205,361,041...205,365,036
Ensembl chr 1:205,361,041...205,364,706
G
Bglap
bone gamma-carboxyglutamate protein
decreases expression increases secretion increases expression multiple interactions
ISO
Vitamin K 3 results in decreased expression of BGLAP mRNA Vitamin K 3 results in increased secretion of BGLAP protein Vitamin K 3 results in increased expression of BGLAP protein modified form Vitamin K 3 inhibits the reaction [Estrogens deficiency results in decreased secretion of BGLAP protein]
CTD
PMID:19675304 PMID:30453296
NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
G
Bik
BCL2-interacting killer
increases expression
ISO
Vitamin K 3 results in increased expression of BIK mRNA
CTD
PMID:23410634
NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317
G
Birc5
baculoviral IAP repeat-containing 5
affects expression
ISO
Vitamin K 3 affects the expression of BIRC5 mRNA
CTD
PMID:20044591
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
G
Blvrb
biliverdin reductase B
increases expression
ISO
Vitamin K 3 results in increased expression of BLVRB mRNA
CTD
PMID:25270620
NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
G
Bms1
BMS1 ribosome biogenesis factor
affects expression
ISO
Vitamin K 3 affects the expression of BMS1 mRNA
CTD
PMID:20044591
NCBI chr 4:153,230,471...153,267,437
Ensembl chr 4:153,230,471...153,267,429
G
Bnip3
BCL2 interacting protein 3
decreases expression
ISO
Vitamin K 3 results in decreased expression of BNIP3 mRNA
CTD
PMID:25270620
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
G
Brd8
bromodomain containing 8
affects expression
ISO
Vitamin K 3 affects the expression of BRD8 mRNA
CTD
PMID:20044591
NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006
G
Brms1
BRMS1, transcriptional repressor and anoikis regulator
affects expression
ISO
Vitamin K 3 affects the expression of BRMS1 mRNA
CTD
PMID:20044591
NCBI chr 1:211,775,142...211,784,411
Ensembl chr 1:211,775,095...211,784,410
G
Btg2
BTG anti-proliferation factor 2
increases expression
ISO
Vitamin K 3 results in increased expression of BTG2 mRNA
CTD
PMID:12414654 PMID:21382384
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
affects expression
ISO
Vitamin K 3 affects the expression of BUB1 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
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Bud13
BUD13 homolog
affects expression
ISO
Vitamin K 3 affects the expression of BUD13 mRNA
CTD
PMID:20044591
NCBI chr 8:55,471,818...55,487,652
Ensembl chr 8:55,471,810...55,487,649
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C10h17orf100
similar to human chromosome 17 open reading frame 100
affects expression
ISO
Vitamin K 3 affects the expression of C17ORF100 mRNA
CTD
PMID:23410634
NCBI chr10:57,339,186...57,342,233
Ensembl chr10:57,337,035...57,341,474
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C11h3orf52
similar to human chromosome 3 open reading frame 52
affects expression
ISO
Vitamin K 3 affects the expression of C3ORF52 mRNA
CTD
PMID:20044591
NCBI chr11:68,629,570...68,654,874
Ensembl chr11:68,629,570...68,654,868
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C17h6orf62
similar to human chromosome 6 open reading frame 62
affects expression
ISO
Vitamin K 3 affects the expression of C6ORF62 mRNA
CTD
PMID:23410634
NCBI chr17:40,684,236...40,695,874
Ensembl chr17:40,684,236...40,704,043
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C1galt1c1
C1GALT1-specific chaperone 1
affects expression
ISO
Vitamin K 3 affects the expression of C1GALT1C1 mRNA
CTD
PMID:20044591
NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422
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C1qbp
complement C1q binding protein
affects expression
ISO
Vitamin K 3 affects the expression of C1QBP mRNA
CTD
PMID:20044591
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
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C2cd5
C2 calcium-dependent domain containing 5
affects expression
ISO
Vitamin K 3 affects the expression of C2CD5 mRNA
CTD
PMID:20044591
NCBI chr 4:177,700,515...177,790,576
Ensembl chr 4:177,700,516...177,786,717
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C7h8orf76
similar to human chromosome 8 open reading frame 76
affects expression
ISO
Vitamin K 3 affects the expression of C8ORF76 mRNA
CTD
PMID:23410634
NCBI chr 7:91,448,422...91,459,284
Ensembl chr 7:91,443,270...91,462,404
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C8h15orf39
similar to human chromosome 15 open reading frame 39
affects expression
ISO
Vitamin K 3 affects the expression of C15ORF39 mRNA
CTD
PMID:20044591
NCBI chr 8:66,542,269...66,551,835
Ensembl chr 8:66,542,269...66,554,782
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Ca12
carbonic anhydrase 12
affects expression
ISO
Vitamin K 3 affects the expression of CA12 mRNA
CTD
PMID:20044591
NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465
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Cables1
Cdk5 and Abl enzyme substrate 1
affects expression
ISO
Vitamin K 3 affects the expression of CABLES1 mRNA
CTD
PMID:20044591
NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956
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Cacna1g
calcium voltage-gated channel subunit alpha1 G
affects expression
ISO
Vitamin K 3 affects the expression of CACNA1G mRNA
CTD
PMID:20044591
NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634
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Calb1
calbindin 1
increases expression
ISO
Vitamin K 3 results in increased expression of CALB1 mRNA
CTD
PMID:30453296
NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160
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Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
affects expression
ISO
Vitamin K 3 affects the expression of CAMK2N1 mRNA
CTD
PMID:20044591
NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058
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Canx
calnexin
affects expression
ISO
Vitamin K 3 affects the expression of CANX mRNA
CTD
PMID:20044591
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857
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Capn2
calpain 2
affects expression
ISO
Vitamin K 3 affects the expression of CAPN2 mRNA
CTD
PMID:23410634
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
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Casp2
caspase 2
increases expression
ISO
Vitamin K 3 results in increased expression of CASP2 protein modified form
CTD
PMID:20829426
NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022
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Casp3
caspase 3
multiple interactions increases activity increases cleavage increases expression
ISO EXP
[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Vitamin K 3 analog inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP3 protein] Vitamin K 3 results in increased activity of CASP3 protein Vitamin K 3 results in increased cleavage of CASP3 protein Buthionine Sulfoximine promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP3 protein]; U 0126 promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein] Vitamin K 3 results in increased expression of CASP3 protein modified form
CTD
PMID:12965111 PMID:16310883 PMID:19082730 PMID:20829426 PMID:23300732 PMID:29141199 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp4
caspase 4
multiple interactions
ISO
[Metyrapone co-treated with Vitamin K 3] affects the localization of CASP4 protein; [S 3483 co-treated with Vitamin K 3] affects the localization of CASP4 protein
CTD
PMID:19819344
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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Casp6
caspase 6
multiple interactions increases cleavage
EXP
pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased activity of CASP6 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP6 protein]
CTD
PMID:16310883
NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726
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Casp9
caspase 9
multiple interactions increases cleavage
ISO EXP
[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP9 protein] pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]
CTD
PMID:16310883 PMID:19082730 PMID:25005833 PMID:29141199
Ensembl chr 5:159,391,188...159,409,648
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Cat
catalase
affects expression decreases activity decreases response to substance multiple interactions
ISO EXP
Vitamin K 3 affects the expression of CAT mRNA Vitamin K 3 results in decreased activity of CAT protein CAT protein results in decreased susceptibility to Vitamin K 3 [CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3; [CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]
CTD
PMID:12633745 PMID:14698046 PMID:15331536 PMID:20044591 PMID:21689642 PMID:22486562 PMID:28595002 PMID:30536483 More...
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Cavin2
caveolae associated protein 2
affects expression
ISO
Vitamin K 3 affects the expression of CAVIN2 mRNA
CTD
PMID:23410634
NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024
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Cbfb
core-binding factor subunit beta
affects expression
ISO
Vitamin K 3 affects the expression of CBFB mRNA
CTD
PMID:20044591
NCBI chr19:49,955,133...50,002,661
Ensembl chr19:49,959,096...50,002,657
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Cbr1
carbonyl reductase 1
multiple interactions increases metabolic processing
ISO
[S-Nitrosoglutathione binds to CBR1 protein] inhibits the reaction [CBR1 protein results in increased metabolism of Vitamin K 3]; Vitamin K 3 inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
CTD
PMID:11306090 PMID:19061875 PMID:23295225
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
G
Cbr3
carbonyl reductase 3
affects metabolic processing increases expression
ISO
CBR3 protein affects the metabolism of Vitamin K 3 Vitamin K 3 results in increased expression of CBR3 mRNA
CTD
PMID:20007405 PMID:21382384 PMID:25270620
NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558
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Ccar2
cell cycle and apoptosis regulator 2
affects expression
ISO
Vitamin K 3 affects the expression of CCAR2 mRNA
CTD
PMID:20044591
NCBI chr15:51,622,519...51,637,911
Ensembl chr15:51,622,464...51,637,774
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Ccdc12
coiled-coil domain containing 12
affects expression
ISO
Vitamin K 3 affects the expression of CCDC12 mRNA
CTD
PMID:20044591
NCBI chr 8:119,513,007...119,564,802
Ensembl chr 8:119,514,094...119,564,802
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Ccdc125
coiled-coil domain containing 125
affects expression
ISO
Vitamin K 3 affects the expression of CCDC125 mRNA
CTD
PMID:20044591
NCBI chr 2:33,542,916...33,568,501
Ensembl chr 2:33,543,300...33,568,288
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Ccdc136
coiled-coil domain containing 136
decreases expression
ISO
Vitamin K 3 results in decreased expression of CCDC136 mRNA
CTD
PMID:25270620
NCBI chr 4:58,963,196...58,992,962
Ensembl chr 4:58,962,908...58,992,975
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Ccdc88b
coiled-coil domain containing 88B
affects expression
ISO
Vitamin K 3 affects the expression of CCDC88B mRNA
CTD
PMID:20044591
NCBI chr 1:213,466,139...213,482,099
Ensembl chr 1:213,461,963...213,522,302
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Ccdc90b
coiled-coil domain containing 90B
affects expression
ISO
Vitamin K 3 affects the expression of CCDC90B mRNA
CTD
PMID:20044591
NCBI chr 1:156,045,192...156,058,750
Ensembl chr 1:156,045,138...156,061,403
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Ccl3
C-C motif chemokine ligand 3
multiple interactions increases secretion increases expression
EXP
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL3 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL3 protein]
CTD
PMID:19265712
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
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Ccl5
C-C motif chemokine ligand 5
multiple interactions increases secretion increases expression
EXP
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL5 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL5 protein]
CTD
PMID:19265712
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
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Ccn1
cellular communication network factor 1
increases expression
ISO
Vitamin K 3 results in increased expression of CCN1 mRNA
CTD
PMID:12414654
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
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Ccn2
cellular communication network factor 2
affects expression
ISO
Vitamin K 3 affects the expression of CCN2 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
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Ccna2
cyclin A2
decreases expression affects expression
ISO
Vitamin K 3 results in decreased expression of CCNA2 mRNA Vitamin K 3 affects the expression of CCNA2 mRNA
CTD
PMID:12414654 PMID:23410634
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
G
Ccnb2
cyclin B2
affects expression
ISO
Vitamin K 3 affects the expression of CCNB2 mRNA
CTD
PMID:20044591
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
G
Ccnd1
cyclin D1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of CCND1 mRNA Vitamin K 3 results in decreased expression of CCND1 protein
CTD
PMID:20044591 PMID:31238027
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccne1
cyclin E1
affects expression
ISO
Vitamin K 3 affects the expression of CCNE1 mRNA
CTD
PMID:20044591
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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Ccng1
cyclin G1
affects expression
ISO
Vitamin K 3 affects the expression of CCNG1 mRNA
CTD
PMID:20044591
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
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Ccni
cyclin I
affects expression
ISO
Vitamin K 3 affects the expression of CCNI mRNA
CTD
PMID:20044591
NCBI chr14:15,164,047...15,186,885
Ensembl chr14:15,164,095...15,186,885
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Ccnjl
cyclin J-like
affects expression
ISO
Vitamin K 3 affects the expression of CCNJL mRNA
CTD
PMID:20044591
NCBI chr10:28,497,144...28,554,877
Ensembl chr10:28,496,990...28,554,877
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Ccnq
cyclin Q
affects expression
ISO
Vitamin K 3 affects the expression of CCNQ mRNA
CTD
PMID:20044591
NCBI chr10:64,144,560...64,145,723
Ensembl chr10:64,144,555...64,145,911
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Cct2
chaperonin containing TCP1 subunit 2
affects expression
ISO
Vitamin K 3 affects the expression of CCT2 mRNA
CTD
PMID:20044591
NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
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Cct5
chaperonin containing TCP1 subunit 5
affects expression
ISO
Vitamin K 3 affects the expression of CCT5 mRNA
CTD
PMID:20044591
NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779
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Cd1d1
CD1d1 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD1D mRNA
CTD
PMID:20829426
NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029
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Cd36
CD36 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD36 mRNA
CTD
PMID:20829426
NCBI chr 4:18,209,088...18,302,142
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Cd44
CD44 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD44 mRNA
CTD
PMID:20829426
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
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Cd48
Cd48 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD48 mRNA
CTD
PMID:20829426
NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942
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Cd74
CD74 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD74 mRNA
CTD
PMID:20829426
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
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Cd9
CD9 molecule
affects expression
ISO
Vitamin K 3 affects the expression of CD9 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444
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Cdc14b
cell division cycle 14B
affects expression
ISO
Vitamin K 3 affects the expression of CDC14B mRNA
CTD
PMID:20044591
NCBI chr17:850,272...938,972
Ensembl chr17:850,390...971,164
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Cdc42ep4
CDC42 effector protein 4
affects expression
ISO
Vitamin K 3 affects the expression of CDC42EP4 mRNA
CTD
PMID:23410634
NCBI chr10:99,271,750...99,298,551
Ensembl chr10:99,267,540...99,300,168
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Cdc45
cell division cycle 45
affects expression
ISO
Vitamin K 3 affects the expression of CDC45 mRNA
CTD
PMID:20044591
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
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Cdca5
cell division cycle associated 5
affects expression
ISO
Vitamin K 3 affects the expression of CDCA5 mRNA
CTD
PMID:20044591
NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309
G
Cdca7
cell division cycle associated 7
affects expression
ISO
Vitamin K 3 affects the expression of CDCA7 mRNA
CTD
PMID:20044591
NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947
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Cdh1
cadherin 1
increases expression
ISO
Vitamin K 3 results in increased expression of CDH1 protein
CTD
PMID:31238027
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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Cdh16
cadherin 16
affects expression
ISO
Vitamin K 3 affects the expression of CDH16 mRNA
CTD
PMID:20044591
NCBI chr19:367,202...377,710
Ensembl chr19:367,274...388,934
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Cdh2
cadherin 2
decreases expression
ISO
Vitamin K 3 results in decreased expression of CDH2 protein
CTD
PMID:31238027
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
G
Cdk4
cyclin-dependent kinase 4
decreases expression
ISO
Vitamin K 3 results in decreased expression of CDK4 mRNA
CTD
PMID:16010434
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions increases expression
ISO
[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein; EUK-134 affects the reaction [Vitamin K 3 results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein] Vitamin K 3 results in increased expression of CDKN1A mRNA; Vitamin K 3 results in increased expression of CDKN1A protein
CTD
PMID:12414654 PMID:19082730 PMID:23410634 PMID:25005833
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions
ISO
[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein]
CTD
PMID:19082730
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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Cdkn1c
cyclin-dependent kinase inhibitor 1C
affects expression
ISO
Vitamin K 3 affects the expression of CDKN1C mRNA
CTD
PMID:20044591
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
increases expression
ISO
Vitamin K 3 results in increased expression of CDKN2A mRNA
CTD
PMID:16010434
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
G
Cdt1
chromatin licensing and DNA replication factor 1
affects expression
ISO
Vitamin K 3 affects the expression of CDT1 mRNA
CTD
PMID:20044591
NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194
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Cdx1
caudal type homeo box 1
increases expression
ISO
Vitamin K 3 results in increased expression of CDX1 mRNA
CTD
PMID:25270620
NCBI chr18:56,742,970...56,761,299
Ensembl chr18:56,742,984...56,761,299
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Cebpa
CCAAT/enhancer binding protein alpha
affects expression
ISO
Vitamin K 3 affects the expression of CEBPA mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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Cenpa
centromere protein A
decreases expression
ISO
Vitamin K 3 results in decreased expression of CENPA mRNA
CTD
PMID:12414654
NCBI chr 6:31,420,062...31,431,703
G
Cenpf
centromere protein F
affects expression
ISO
Vitamin K 3 affects the expression of CENPF mRNA
CTD
PMID:20044591
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
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Cep95
centrosomal protein 95
affects expression
ISO
Vitamin K 3 affects the expression of CEP95 mRNA
CTD
PMID:20044591
NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810
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Cfap20
cilia and flagella associated protein 20
affects expression
ISO
Vitamin K 3 affects the expression of CFAP20 mRNA
CTD
PMID:20044591
NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612
G
Cgnl1
cingulin-like 1
affects expression
ISO
Vitamin K 3 affects the expression of CGNL1 mRNA
CTD
PMID:20044591
NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747
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Chek1
checkpoint kinase 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of CHEK1 mRNA
CTD
PMID:12414654
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
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Chka
choline kinase alpha
affects expression
ISO
Vitamin K 3 affects the expression of CHKA mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752
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Chpf2
chondroitin polymerizing factor 2
increases expression
ISO
Vitamin K 3 results in increased expression of CHPF2 mRNA
CTD
PMID:25270620
NCBI chr 4:11,470,917...11,479,096
Ensembl chr 4:11,472,908...11,478,370
G
Chst15
carbohydrate sulfotransferase 15
affects expression
ISO
Vitamin K 3 affects the expression of CHST15 mRNA
CTD
PMID:23410634
NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:196,460,425...196,491,444
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Chst7
carbohydrate sulfotransferase 7
affects expression
ISO
Vitamin K 3 affects the expression of CHST7 mRNA
CTD
PMID:20044591
NCBI chr X:4,949,810...4,986,372
Ensembl chr X:4,938,757...4,986,907
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Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
affects expression
ISO
Vitamin K 3 affects the expression of CITED2 mRNA
CTD
PMID:20044591
NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782
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Ckap5
cytoskeleton associated protein 5
affects expression
ISO
Vitamin K 3 affects the expression of CKAP5 mRNA
CTD
PMID:20044591
NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049
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Ckb
creatine kinase B
affects expression
ISO
Vitamin K 3 affects the expression of CKB mRNA
CTD
PMID:20044591
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
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Cks1b
CDC28 protein kinase regulatory subunit 1B
affects expression
ISO
Vitamin K 3 affects the expression of CKS1B mRNA
CTD
PMID:20044591
NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
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Cldn23
claudin 23
affects expression
ISO
Vitamin K 3 affects the expression of CLDN23 mRNA
CTD
PMID:20044591
NCBI chr16:63,117,045...63,118,769
Ensembl chr16:63,116,781...63,118,957
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Cldn3
claudin 3
affects expression
ISO
Vitamin K 3 affects the expression of CLDN3 mRNA
CTD
PMID:20044591
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
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Clip1
CAP-GLY domain containing linker protein 1
affects expression
ISO
Vitamin K 3 affects the expression of CLIP1 mRNA
CTD
PMID:20044591
NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779
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Clpb
ClpB family mitochondrial disaggregase
affects expression
ISO
Vitamin K 3 affects the expression of CLPB mRNA
CTD
PMID:20044591
NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:165,440,861...165,583,815
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Cmbl
carboxymethylenebutenolidase homolog
affects expression
ISO
Vitamin K 3 affects the expression of CMBL mRNA
CTD
PMID:20044591
NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
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Cmip
c-Maf-inducing protein
affects expression
ISO
Vitamin K 3 affects the expression of CMIP mRNA
CTD
PMID:20044591
NCBI chr19:62,213,402...62,419,443
Ensembl chr19:62,213,365...62,417,500
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Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
affects expression
ISO
Vitamin K 3 affects the expression of CMTM3 mRNA
CTD
PMID:20044591
NCBI chr19:629,000...637,152
Ensembl chr19:628,895...636,225
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Cntnap2
contactin associated protein 2
affects expression
ISO
Vitamin K 3 affects the expression of CNTNAP2 mRNA
CTD
PMID:20044591
NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258
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Coa4
cytochrome c oxidase assembly factor 4 homolog
affects expression
ISO
Vitamin K 3 affects the expression of COA4 mRNA
CTD
PMID:20044591
NCBI chr 1:164,294,312...164,297,571
Ensembl chr 1:164,294,319...164,297,578
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Coa5
cytochrome C oxidase assembly factor 5
affects expression
ISO
Vitamin K 3 affects the expression of COA5 mRNA
CTD
PMID:20044591
NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
Vitamin K 3 results in decreased expression of COL1A1 mRNA
CTD
PMID:19675304
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
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Col5a2
collagen type V alpha 2 chain
affects expression
ISO
Vitamin K 3 affects the expression of COL5A2 mRNA
CTD
PMID:20044591
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150
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Coro2a
coronin 2A
affects expression
ISO
Vitamin K 3 affects the expression of CORO2A mRNA
CTD
PMID:20044591
NCBI chr 5:65,623,820...65,677,483
Ensembl chr 5:65,623,823...65,654,602
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Creb1
cAMP responsive element binding protein 1
multiple interactions
ISO
[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of CREB1 protein
CTD
PMID:19082730
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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Crip1
cysteine rich protein 1
affects expression
ISO
Vitamin K 3 affects the expression of CRIP1 mRNA
CTD
PMID:20044591
NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:138,047,801...138,055,672
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Cryl1
crystallin, lambda 1
affects expression
ISO
Vitamin K 3 affects the expression of CRYL1 mRNA
CTD
PMID:20044591
NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563
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Ctbp2
C-terminal binding protein 2
affects expression
ISO
Vitamin K 3 affects the expression of CTBP2 mRNA
CTD
PMID:20044591
NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261
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Ctf1
cardiotrophin 1
multiple interactions increases expression
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 2-methoxyestradiol inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; diphenyleneiodonium inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein] Vitamin K 3 results in increased expression of CTF1 mRNA; Vitamin K 3 results in increased expression of CTF1 protein
CTD
PMID:16507596
NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395
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Ctnnb1
catenin beta 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of CTNNB1 protein
CTD
PMID:31238027
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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Ctnnd1
catenin delta 1
affects expression
ISO
Vitamin K 3 affects the expression of CTNND1 mRNA
CTD
PMID:20044591
NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189
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Ctps1
CTP synthase 1
affects expression
ISO
Vitamin K 3 affects the expression of CTPS1 mRNA
CTD
PMID:20044591
NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465
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Ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
affects expression
ISO
Vitamin K 3 affects the expression of CTR9 mRNA
CTD
PMID:20044591
NCBI chr 1:174,571,952...174,601,974
Ensembl chr 1:174,571,928...174,602,130
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Cul4a
cullin 4A
affects expression
ISO
Vitamin K 3 affects the expression of CUL4A mRNA
CTD
PMID:20044591
NCBI chr16:83,086,688...83,124,503
Ensembl chr16:83,086,921...83,124,457
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Cxxc5
CXXC finger protein 5
affects expression
ISO
Vitamin K 3 affects the expression of CXXC5 mRNA
CTD
PMID:20044591
NCBI chr18:27,701,650...27,732,633
Ensembl chr18:27,701,188...27,732,635
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Cyb5d2
cytochrome b5 domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of CYB5D2 mRNA
CTD
PMID:23410634
NCBI chr10:57,892,799...57,911,831
Ensembl chr10:57,895,296...57,912,030
G
Cyb5r1
cytochrome b5 reductase 1
affects expression
ISO
Vitamin K 3 affects the expression of CYB5R1 mRNA
CTD
PMID:20044591
NCBI chr13:48,401,061...48,407,466
Ensembl chr13:48,399,106...48,407,465
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Cyba
cytochrome b-245 alpha chain
increases expression
ISO
Vitamin K 3 results in increased expression of CYBA protein
CTD
PMID:16507596
NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases activity increases expression
ISO EXP
Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] Vitamin K 3 results in increased activity of CYP1A1 protein Vitamin K 3 results in increased expression of CYP1A1 mRNA
CTD
PMID:15603920 PMID:18493746
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions increases expression increases activity
ISO EXP
Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] Vitamin K 3 results in increased expression of CYP1A2 mRNA Vitamin K 3 results in increased activity of CYP1A2 protein
CTD
PMID:15603920 PMID:18493746
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
ISO
Vitamin K 3 results in increased expression of CYP1B1 mRNA
CTD
PMID:12414654
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
affects expression
ISO
Vitamin K 3 affects the expression of CYP24A1 mRNA
CTD
PMID:23410634
NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression multiple interactions
ISO
Vitamin K 3 results in decreased expression of CYP2E1 mRNA [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein; Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]
CTD
PMID:22486562 PMID:25270620
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
ISO
Vitamin K 3 affects the expression of CYP2J9 mRNA
CTD
PMID:20829426
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
G
Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
affects expression
ISO
Vitamin K 3 affects the expression of CYP2R1 mRNA
CTD
PMID:20044591
NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423
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Dbi
diazepam binding inhibitor
affects expression
ISO
Vitamin K 3 affects the expression of DBI mRNA
CTD
PMID:20044591
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
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Dcp1b
decapping mRNA 1B
affects expression
ISO
Vitamin K 3 affects the expression of DCP1B mRNA
CTD
PMID:20044591
NCBI chr 4:154,030,181...154,068,038
Ensembl chr 4:154,030,690...154,068,035
G
Dcxr
dicarbonyl and L-xylulose reductase
multiple interactions increases metabolic processing decreases activity
ISO
[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide; [DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides; [Vitamin K 3 co-treated with NADP] binds to DCXR protein; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; Diacetyl inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides]; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin] Vitamin K 3 results in decreased activity of DCXR protein
CTD
PMID:25526675 PMID:28595002
NCBI chr10:106,504,730...106,506,619
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Ddc
dopa decarboxylase
affects expression
ISO
Vitamin K 3 affects the expression of DDC mRNA
CTD
PMID:20044591
NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
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Ddit3
DNA-damage inducible transcript 3
increases expression multiple interactions
ISO
Vitamin K 3 results in increased expression of DDIT3 mRNA; Vitamin K 3 results in increased expression of DDIT3 protein Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]
CTD
PMID:12414654 PMID:19819344
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Ddit4
DNA-damage-inducible transcript 4
affects expression
ISO
Vitamin K 3 affects the expression of DDIT4 mRNA
CTD
PMID:23410634
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
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Ddit4l
DNA-damage-inducible transcript 4-like
increases expression
ISO
Vitamin K 3 results in increased expression of DDIT4L mRNA
CTD
PMID:25270620
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
G
Ddx1
DEAD-box helicase 1
affects expression
ISO
Vitamin K 3 affects the expression of DDX1 mRNA
CTD
PMID:20044591
NCBI chr 6:41,725,365...41,756,236
Ensembl chr 6:41,725,367...41,758,302
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Ddx23
DEAD-box helicase 23
affects expression
ISO
Vitamin K 3 affects the expression of DDX23 mRNA
CTD
PMID:20044591
NCBI chr 7:131,676,636...131,693,917
Ensembl chr 7:131,676,636...131,689,074
G
Ddx42
DEAD-box helicase 42
increases expression
ISO
Vitamin K 3 results in increased expression of DDX42 mRNA
CTD
PMID:12414654
NCBI chr10:91,648,719...91,680,730
Ensembl chr10:91,648,248...91,680,729
G
Ddx47
DEAD-box helicase 47
affects expression
ISO
Vitamin K 3 affects the expression of DDX47 mRNA
CTD
PMID:20044591
NCBI chr 4:169,577,013...169,589,473
Ensembl chr 4:169,577,003...169,590,474
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Defb1
defensin beta 1
affects expression
ISO
Vitamin K 3 affects the expression of DEFB1 mRNA
CTD
PMID:20044591
NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068
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Depdc7
DEP domain containing 7
affects expression
ISO
Vitamin K 3 affects the expression of DEPDC7 mRNA
CTD
PMID:20044591
NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:111,554,706...111,575,979
G
Deptor
DEP domain containing MTOR-interacting protein
affects expression
ISO
Vitamin K 3 affects the expression of DEPTOR mRNA
CTD
PMID:20044591
NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
G
Desi2
desumoylating isopeptidase 2
affects expression
ISO
Vitamin K 3 affects the expression of DESI2 mRNA
CTD
PMID:20044591
NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981
G
Dgat1
diacylglycerol O-acyltransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of DGAT1 mRNA
CTD
PMID:20044591
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
G
Dgat2
diacylglycerol O-acyltransferase 2
affects expression
ISO
Vitamin K 3 affects the expression of DGAT2 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
G
Dgkd
diacylglycerol kinase, delta
affects expression
ISO
Vitamin K 3 affects the expression of DGKD mRNA
CTD
PMID:20044591
NCBI chr 9:95,964,507...96,055,160
Ensembl chr 9:95,964,148...96,055,160
G
Dhrs11
dehydrogenase/reductase 11
increases reduction
ISO
DHRS11 protein results in increased reduction of Vitamin K 3
CTD
PMID:30926317
NCBI chr10:70,195,637...70,205,735
Ensembl chr10:70,195,637...70,205,893
G
Dhx35
DEAH-box helicase 35
affects expression
ISO
Vitamin K 3 affects the expression of DHX35 mRNA
CTD
PMID:20044591
NCBI chr 3:167,869,971...167,927,300
Ensembl chr 3:167,870,055...167,927,300
G
Dhx9
DExH-box helicase 9
affects expression
ISO
Vitamin K 3 affects the expression of DHX9 mRNA
CTD
PMID:20044591
NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546
G
Dipk1b
divergent protein kinase domain 1B
affects expression
ISO
Vitamin K 3 affects the expression of DIPK1B mRNA
CTD
PMID:20044591
NCBI chr 3:29,852,710...29,862,248
Ensembl chr 3:29,853,973...29,862,255
G
Dkc1
dyskerin pseudouridine synthase 1
affects expression
ISO
Vitamin K 3 affects the expression of DKC1 mRNA
CTD
PMID:20044591
NCBI chr X:157,751,651...157,757,796
Ensembl chr Y:380,743...385,405 Ensembl chr X:380,743...385,405
G
Dkk1
dickkopf WNT signaling pathway inhibitor 1
affects expression increases expression
ISO
Vitamin K 3 affects the expression of DKK1 mRNA Vitamin K 3 results in increased expression of DKK1 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
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Dlgap5
DLG associated protein 5
affects expression
ISO
Vitamin K 3 affects the expression of DLGAP5 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
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Dmd
dystrophin
increases response to substance
ISO
DMD gene mutant form results in increased susceptibility to Vitamin K 3
CTD
PMID:10797403
NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835
G
Dmrt1
doublesex and mab-3 related transcription factor 1
increases expression
ISO
Vitamin K 3 results in increased expression of DMRT1 mRNA
CTD
PMID:25270620
NCBI chr 1:232,569,179...232,667,646
Ensembl chr 1:232,569,072...232,668,370
G
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
affects expression
ISO
Vitamin K 3 affects the expression of DNAJB1 mRNA
CTD
PMID:20044591
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
G
Dnajc14
DnaJ heat shock protein family (Hsp40) member C14
affects expression
ISO
Vitamin K 3 affects the expression of DNAJC14 mRNA
CTD
PMID:20044591
NCBI chr 7:1,818,360...1,831,642
Ensembl chr 7:1,820,247...1,831,658
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Dnm1l
dynamin 1-like
affects expression
ISO
Vitamin K 3 affects the expression of DNM1L mRNA
CTD
PMID:20829426
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
G
Dnmt3b
DNA methyltransferase 3 beta
affects expression
ISO
Vitamin K 3 affects the expression of DNMT3B mRNA
CTD
PMID:20044591
NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313
G
Dnmt3l
DNA methyltransferase 3 like
decreases expression
ISO
Vitamin K 3 results in decreased expression of DNMT3L mRNA
CTD
PMID:25270620
NCBI chr20:10,614,591...10,628,989
Ensembl chr20:10,614,591...10,629,168
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Dph1
diphthamide biosynthesis 1
affects expression
ISO
Vitamin K 3 affects the expression of DPH1 mRNA
CTD
PMID:20044591
NCBI chr10:60,526,417...60,538,102
Ensembl chr10:60,527,680...60,535,816
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Dph3
diphthamide biosynthesis 3
affects expression
ISO
Vitamin K 3 affects the expression of DPH3 mRNA
CTD
PMID:20044591
NCBI chr16:7,294,580...7,299,996
Ensembl chr16:7,294,580...7,299,996
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Dpm3
dolichyl-phosphate mannosyltransferase subunit 3, regulatory
affects expression
ISO
Vitamin K 3 affects the expression of DPM3 mRNA
CTD
PMID:20044591
NCBI chr 2:176,974,290...176,974,805
Ensembl chr15:52,612,418...52,612,696
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
ISO
Vitamin K 3 affects the expression of DPYD mRNA
CTD
PMID:20829426
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
G
Dusp1
dual specificity phosphatase 1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of DUSP1 mRNA Vitamin K 3 results in decreased expression of DUSP1 mRNA
CTD
PMID:23410634 PMID:25270620
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
G
Dusp2
dual specificity phosphatase 2
affects expression
ISO
Vitamin K 3 affects the expression of DUSP2 mRNA
CTD
PMID:20044591
NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809
G
Dusp3
dual specificity phosphatase 3
affects expression
ISO
Vitamin K 3 affects the expression of DUSP3 mRNA
CTD
PMID:20044591
NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063
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Dusp6
dual specificity phosphatase 6
affects expression
ISO
Vitamin K 3 affects the expression of DUSP6 mRNA
CTD
PMID:20044591
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
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Dusp9
dual specificity phosphatase 9
affects expression
ISO
Vitamin K 3 affects the expression of DUSP9 mRNA
CTD
PMID:23410634
NCBI chr X:156,503,237...156,507,162
Ensembl chr X:156,503,190...156,507,161
G
Dync1h1
dynein cytoplasmic 1 heavy chain 1
affects expression
ISO
Vitamin K 3 affects the expression of DYNC1H1 mRNA
CTD
PMID:20044591
NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116
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Dync1li2
dynein, cytoplasmic 1 light intermediate chain 2
affects expression
ISO
Vitamin K 3 affects the expression of DYNC1LI2 mRNA
CTD
PMID:20044591
NCBI chr19:538,207...561,110
Ensembl chr19:538,211...561,107
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Dyrk2
dual specificity tyrosine phosphorylation regulated kinase 2
affects expression
ISO
Vitamin K 3 affects the expression of DYRK2 mRNA
CTD
PMID:20044591
NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:56,235,276...56,265,942
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E2f1
E2F transcription factor 1
affects expression
ISO
Vitamin K 3 affects the expression of E2F1 mRNA
CTD
PMID:20044591
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
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E2f3
E2F transcription factor 3
affects expression
ISO
Vitamin K 3 affects the expression of E2F3 mRNA
CTD
PMID:20044591
NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
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Ebna1bp2
EBNA1 binding protein 2
affects expression
ISO
Vitamin K 3 affects the expression of EBNA1BP2 mRNA
CTD
PMID:20044591
NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637
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Ecpas
Ecm29 proteasome adaptor and scaffold
affects expression
ISO
Vitamin K 3 affects the expression of ECPAS mRNA
CTD
PMID:20044591
NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908
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Edc3
enhancer of mRNA decapping 3
affects expression
ISO
Vitamin K 3 affects the expression of EDC3 mRNA
CTD
PMID:20044591
NCBI chr 8:67,002,032...67,047,563
Ensembl chr 8:67,002,014...67,047,559
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Edn1
endothelin 1
increases expression affects expression
ISO
Vitamin K 3 results in increased expression of EDN1 mRNA Vitamin K 3 affects the expression of EDN1 mRNA
CTD
PMID:12414654 PMID:20044591 PMID:23410634
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
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Efnb2
ephrin B2
decreases expression
ISO
Vitamin K 3 results in decreased expression of EFNB2 mRNA
CTD
PMID:25270620
NCBI chr16:87,485,215...87,529,224
Ensembl chr16:87,485,198...87,529,208
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Egfr
epidermal growth factor receptor
increases phosphorylation
EXP
Vitamin K 3 results in increased phosphorylation of EGFR protein
CTD
PMID:15843167
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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Egln3
egl-9 family hypoxia-inducible factor 3
decreases expression
ISO
Vitamin K 3 results in decreased expression of EGLN3 mRNA
CTD
PMID:25270620
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015
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Egr1
early growth response 1
increases expression affects expression
ISO
Vitamin K 3 results in increased expression of EGR1 mRNA Vitamin K 3 affects the expression of EGR1 mRNA
CTD
PMID:12414654 PMID:20044591 PMID:23410634
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
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Ehmt1
euchromatic histone lysine methyltransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of EHMT1 mRNA
CTD
PMID:20044591
NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349
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Eif3c
eukaryotic translation initiation factor 3, subunit C
affects expression
ISO
Vitamin K 3 affects the expression of EIF3C mRNA
CTD
PMID:20044591
NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067
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Eif3j
eukaryotic translation initiation factor 3, subunit J
affects expression
ISO
Vitamin K 3 affects the expression of EIF3J mRNA
CTD
PMID:20044591
NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246
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Eif4a1
eukaryotic translation initiation factor 4A1
affects expression
ISO
Vitamin K 3 affects the expression of EIF4A1 mRNA
CTD
PMID:20044591
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
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Eif4b
eukaryotic translation initiation factor 4B
affects expression
ISO
Vitamin K 3 affects the expression of EIF4B mRNA
CTD
PMID:20044591
NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064
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Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
affects expression
ISO
Vitamin K 3 affects the expression of EIF4ENIF1 mRNA
CTD
PMID:20044591
NCBI chr14:82,280,566...82,328,559
Ensembl chr14:82,280,748...82,323,242
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Eif4g2
eukaryotic translation initiation factor 4, gamma 2
affects expression
ISO
Vitamin K 3 affects the expression of EIF4G2 mRNA
CTD
PMID:20044591
NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252
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Elavl1
ELAV like RNA binding protein 1
multiple interactions increases phosphorylation
ISO
[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; [Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein; JAK3 protein promotes the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Janus Kinase Inhibitors inhibits the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]]
CTD
PMID:24106086
NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631
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Elavl2
ELAV like RNA binding protein 2
affects expression
ISO
Vitamin K 3 affects the expression of ELAVL2 mRNA
CTD
PMID:20829426
NCBI chr 5:111,076,705...111,202,341
Ensembl chr 5:111,076,705...111,224,918
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Elof1
elongation factor 1
affects expression
ISO
Vitamin K 3 affects the expression of ELOF1 mRNA
CTD
PMID:20044591
NCBI chr 8:28,921,338...28,926,612
Ensembl chr 8:28,921,339...28,926,228
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Emg1
EMG1 N1-specific pseudouridine methyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of EMG1 mRNA
CTD
PMID:20044591
NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826
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Emilin1
elastin microfibril interfacer 1
affects expression
ISO
Vitamin K 3 affects the expression of EMILIN1 mRNA
CTD
PMID:23410634
NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657
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Emp2
epithelial membrane protein 2
affects expression
ISO
Vitamin K 3 affects the expression of EMP2 mRNA
CTD
PMID:20044591
NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532
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Enc1
ectodermal-neural cortex 1
affects expression
ISO
Vitamin K 3 affects the expression of ENC1 mRNA
CTD
PMID:20044591
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
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Enosf1
enolase superfamily member 1
affects expression
ISO
Vitamin K 3 affects the expression of ENOSF1 mRNA
CTD
PMID:20044591
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Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
decreases expression
ISO
Vitamin K 3 results in decreased expression of ENPP3 mRNA
CTD
PMID:25270620
NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314
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Ep300
E1A binding protein p300
decreases expression
ISO
Vitamin K 3 results in decreased expression of EP300 protein
CTD
PMID:31238027
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
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Epas1
endothelial PAS domain protein 1
affects expression
ISO
Vitamin K 3 affects the expression of EPAS1 mRNA
CTD
PMID:20044591
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
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Ephx1
epoxide hydrolase 1
increases expression
ISO
Vitamin K 3 results in increased expression of EPHX1 mRNA
CTD
PMID:21382384
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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Epn2
epsin 2
affects expression
ISO
Vitamin K 3 affects the expression of EPN2 mRNA
CTD
PMID:20044591
NCBI chr10:46,697,238...46,759,128
Ensembl chr10:46,697,238...46,759,092
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Epn3
epsin 3
affects expression
ISO
Vitamin K 3 affects the expression of EPN3 mRNA
CTD
PMID:20044591
NCBI chr10:79,935,857...79,946,121
Ensembl chr10:79,935,857...79,944,235
G
Epo
erythropoietin
multiple interactions
ISO
[Vitamin K 3 results in increased abundance of Hydrogen Peroxide] which results in decreased expression of EPO protein
CTD
PMID:7980410
NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
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Eprs1
glutamyl-prolyl-tRNA synthetase 1
affects expression
ISO
Vitamin K 3 affects the expression of EPRS1 mRNA
CTD
PMID:20044591
NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509
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Eps8l2
EPS8 signaling adaptor L2
affects expression
ISO
Vitamin K 3 affects the expression of EPS8L2 mRNA
CTD
PMID:20044591
NCBI chr 1:205,875,825...205,901,109
Ensembl chr 1:205,875,801...205,901,101
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Erbb3
erb-b2 receptor tyrosine kinase 3
affects expression
ISO
Vitamin K 3 affects the expression of ERBB3 mRNA
CTD
PMID:20044591
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120
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Erbin
erbb2 interacting protein
affects expression
ISO
Vitamin K 3 affects the expression of ERBIN mRNA
CTD
PMID:20044591
NCBI chr 2:36,660,399...36,762,584
Ensembl chr 2:36,660,399...36,762,153
G
Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
Vitamin K 3 binds to ESR1 protein Vitamin K 3 inhibits the reaction [Estradiol binds to ESR1 protein]
CTD
PMID:15081572
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
G
Esrp1
epithelial splicing regulatory protein 1
affects expression
ISO
Vitamin K 3 affects the expression of ESRP1 mRNA
CTD
PMID:20044591
NCBI chr 5:29,224,831...29,279,381
Ensembl chr 5:29,225,360...29,279,278
G
Esrp2
epithelial splicing regulatory protein 2
affects expression
ISO
Vitamin K 3 affects the expression of ESRP2 mRNA
CTD
PMID:20044591
NCBI chr19:50,944,401...50,951,919
Ensembl chr19:50,944,401...50,951,568
G
Esyt2
extended synaptotagmin 2
affects expression
ISO
Vitamin K 3 affects the expression of ESYT2 mRNA
CTD
PMID:20044591
NCBI chr 6:143,359,870...143,455,600
Ensembl chr 6:143,362,694...143,455,593
G
Ets2
ETS proto-oncogene 2, transcription factor
affects expression
ISO
Vitamin K 3 affects the expression of ETS2 mRNA
CTD
PMID:20044591
NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842
G
Exosc10
exosome component 10
affects expression
ISO
Vitamin K 3 affects the expression of EXOSC10 mRNA
CTD
PMID:20044591
NCBI chr 5:164,278,414...164,302,067
Ensembl chr 5:164,278,440...164,302,067
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Exosc8
exosome component 8
affects expression
ISO
Vitamin K 3 affects the expression of EXOSC8 mRNA
CTD
PMID:20044591
NCBI chr 2:141,080,568...141,087,112
Ensembl chr 2:141,080,568...141,087,229
G
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
affects expression
ISO
Vitamin K 3 affects the expression of EZH2 mRNA
CTD
PMID:20044591
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
G
Ezr
ezrin
affects expression
ISO
Vitamin K 3 affects the expression of EZR mRNA
CTD
PMID:20044591
NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573
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F10
coagulation factor X
multiple interactions
EXP
Vitamin K 3 inhibits the reaction [Ethyl Biscoumacetate results in decreased expression of F10 protein]
CTD
PMID:6768192
NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280
G
F2rl1
F2R like trypsin receptor 1
affects expression
ISO
Vitamin K 3 affects the expression of F2RL1 mRNA
CTD
PMID:23410634
NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954
G
F8a1
coagulation factor VIII-associated 1
affects expression
ISO
Vitamin K 3 affects the expression of F8A1 mRNA
CTD
PMID:20044591
NCBI chr X:155,977,859...155,979,373
Ensembl chr X:155,976,941...156,108,974
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Fabp1
fatty acid binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of FABP1 mRNA
CTD
PMID:20044591
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113
G
Faf1
Fas associated factor 1
affects expression
ISO
Vitamin K 3 affects the expression of FAF1 mRNA
CTD
PMID:20044591
NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516
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Fam107b
family with sequence similarity 107, member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM107B mRNA
CTD
PMID:20044591
NCBI chr17:79,387,795...79,594,165
Ensembl chr17:79,387,795...79,594,288
G
Fam111a
FAM111 trypsin like peptidase A
affects expression
ISO
Vitamin K 3 affects the expression of FAM111A mRNA
CTD
PMID:20044591
NCBI chr 1:219,065,542...219,081,213
Ensembl chr 1:219,065,601...219,081,211
G
Fam174b
family with sequence similarity 174, member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM174B mRNA
CTD
PMID:20044591
NCBI chr 1:136,925,162...137,006,082
Ensembl chr 1:136,925,151...137,035,589
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Fam20c
FAM20C, golgi associated secretory pathway kinase
affects expression
ISO
Vitamin K 3 affects the expression of FAM20C mRNA
CTD
PMID:20044591
NCBI chr12:20,940,654...20,999,072
Ensembl chr12:20,940,654...20,998,318
G
Fam217b
family with sequence similarity 217, member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM217B mRNA
CTD
PMID:20044591
NCBI chr 3:185,883,277...185,892,976
Ensembl chr 3:185,883,367...185,892,974
G
Fam222b
family with sequence similarity 222, member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM222B mRNA
CTD
PMID:20044591
NCBI chr10:63,484,651...63,550,422
Ensembl chr10:63,484,652...63,550,288
G
Fam241b
family with sequence similarity 241 member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM241B mRNA
CTD
PMID:20044591
NCBI chr20:30,595,082...30,598,007
Ensembl chr20:30,595,084...30,597,844 Ensembl chr 6:30,595,084...30,597,844
G
Fam89b
family with sequence similarity 89, member B
affects expression
ISO
Vitamin K 3 affects the expression of FAM89B mRNA
CTD
PMID:20044591
NCBI chr 1:212,445,101...212,447,164
Ensembl chr 1:212,445,102...212,446,738
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Fanca
FA complementation group A
affects expression
ISO
Vitamin K 3 affects the expression of FANCA mRNA
CTD
PMID:20044591
NCBI chr19:68,210,562...68,271,080
Ensembl chr19:68,212,643...68,271,019
G
Fancf
FA complementation group F
affects expression
ISO
Vitamin K 3 affects the expression of FANCF mRNA
CTD
PMID:20044591
NCBI chr 1:110,585,054...110,587,870
Ensembl chr 1:110,576,389...110,587,863
G
Farp1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
affects expression
ISO
Vitamin K 3 affects the expression of FARP1 mRNA
CTD
PMID:20044591
NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147
G
Farsb
phenylalanyl-tRNA synthetase subunit beta
affects expression
ISO
Vitamin K 3 affects the expression of FARSB mRNA
CTD
PMID:20044591
NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505
G
Fas
Fas cell surface death receptor
increases expression
ISO
Vitamin K 3 results in increased expression of FAS mRNA
CTD
PMID:12414654
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
G
Faxdc2
fatty acid hydroxylase domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of FAXDC2 mRNA
CTD
PMID:20044591
NCBI chr10:42,747,323...42,772,156
Ensembl chr10:42,747,524...42,781,458
G
Fbln1
fibulin 1
affects expression
ISO
Vitamin K 3 affects the expression of FBLN1 mRNA
CTD
PMID:20044591
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
G
Fbxl15
F-box and leucine-rich repeat protein 15
affects expression
ISO
Vitamin K 3 affects the expression of FBXL15 mRNA
CTD
PMID:20044591
NCBI chr 1:255,131,154...255,133,395
Ensembl chr 1:255,131,154...255,133,427
G
Fbxl16
F-box and leucine-rich repeat protein 16
affects expression
ISO
Vitamin K 3 affects the expression of FBXL16 mRNA
CTD
PMID:20044591
NCBI chr10:15,333,996...15,346,253
Ensembl chr10:15,334,014...15,346,232
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Fbxo11
F-box protein 11
affects expression
ISO
Vitamin K 3 affects the expression of FBXO11 mRNA
CTD
PMID:20044591
NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:12,239,801...12,316,221
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Fbxo21
F-box protein 21
affects expression
ISO
Vitamin K 3 affects the expression of FBXO21 mRNA
CTD
PMID:20044591
NCBI chr12:44,231,918...44,266,035
Ensembl chr12:44,231,923...44,266,035
G
Fbxo30
F-box protein 30
increases expression
ISO
Vitamin K 3 results in increased expression of FBXO30 mRNA
CTD
PMID:23410634
NCBI chr 1:7,475,636...7,491,719
Ensembl chr 1:7,475,575...7,493,199
G
Fcgr2b
Fc gamma receptor 2B
affects expression
ISO
Vitamin K 3 affects the expression of FCGR2B mRNA
CTD
PMID:20829426
NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517
G
Fcsk
fucose kinase
affects expression
ISO
Vitamin K 3 affects the expression of FCSK mRNA
CTD
PMID:20044591
NCBI chr19:55,743,746...55,783,873
Ensembl chr19:55,739,842...55,800,496
G
Fdxr
ferredoxin reductase
affects expression increases expression
ISO
Vitamin K 3 affects the expression of FDXR mRNA Vitamin K 3 results in increased expression of FDXR mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542
G
Fen1
flap structure-specific endonuclease 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of FEN1 mRNA
CTD
PMID:12414654
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
G
Fermt1
FERM domain containing kindlin 1
affects expression
ISO
Vitamin K 3 affects the expression of FERMT1 mRNA
CTD
PMID:20044591
NCBI chr 3:140,624,434...140,666,419
Ensembl chr 3:140,624,434...140,666,419
G
Fgfr2
fibroblast growth factor receptor 2
affects expression
ISO
Vitamin K 3 affects the expression of FGFR2 mRNA
CTD
PMID:20044591
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
G
Fgg
fibrinogen gamma chain
increases expression affects expression
ISO
Vitamin K 3 results in increased expression of FGG mRNA Vitamin K 3 affects the expression of FGG mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
G
Fhit
fragile histidine triad diadenosine triphosphatase
increases response to substance
ISO
FHIT protein results in increased susceptibility to Vitamin K 3
CTD
PMID:19622739
NCBI chr15:16,365,401...17,872,901
Ensembl chr15:16,747,338...17,872,621
G
Fhl2
four and a half LIM domains 2
affects expression
ISO
Vitamin K 3 affects the expression of FHL2 mRNA
CTD
PMID:20044591
NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
G
Fibp
FGF1 intracellular binding protein
affects expression
ISO
Vitamin K 3 affects the expression of FIBP mRNA
CTD
PMID:20044591
NCBI chr 1:212,197,216...212,201,732
Ensembl chr 1:212,197,416...212,201,731
G
Fip1l1
factor interacting with PAPOLA and CPSF1
affects expression
ISO
Vitamin K 3 affects the expression of FIP1L1 mRNA
CTD
PMID:20044591
NCBI chr14:33,969,341...34,030,871
Ensembl chr14:33,971,914...34,029,753
G
Fkbp9
FKBP prolyl isomerase 9
affects expression
ISO
Vitamin K 3 affects the expression of FKBP9 mRNA
CTD
PMID:20044591
NCBI chr 4:87,436,439...87,486,909
Ensembl chr 4:87,436,478...87,508,940
G
Flcn
folliculin
affects expression
ISO
Vitamin K 3 affects the expression of FLCN mRNA
CTD
PMID:20044591
NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309
G
Flnb
filamin B
decreases expression
ISO
Vitamin K 3 results in decreased expression of FLNB mRNA
CTD
PMID:25270620
NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209
G
Flrt3
fibronectin leucine rich transmembrane protein 3
affects expression
ISO
Vitamin K 3 affects the expression of FLRT3 mRNA
CTD
PMID:20044591
NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650
G
Flvcr1
FLVCR choline and heme transporter 1
affects expression
ISO
Vitamin K 3 affects the expression of FLVCR1 mRNA
CTD
PMID:20044591
NCBI chr13:105,117,402...105,139,780
Ensembl chr13:105,117,402...105,139,759
G
Fmr1
fragile X messenger ribonucleoprotein 1
affects expression
ISO
Vitamin K 3 affects the expression of FMR1 mRNA
CTD
PMID:20829426
NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675
G
Fn3krp
fructosamine-3-kinase-related protein
affects expression
ISO
Vitamin K 3 affects the expression of FN3KRP mRNA
CTD
PMID:20044591
NCBI chr10:107,186,695...107,195,419
G
Fndc3a
fibronectin type III domain containing 3a
affects expression
ISO
Vitamin K 3 affects the expression of FNDC3A mRNA
CTD
PMID:20044591
NCBI chr15:54,099,510...54,276,963
Ensembl chr15:54,099,510...54,276,407
G
Focad
focadhesin
affects expression
ISO
Vitamin K 3 affects the expression of FOCAD mRNA
CTD
PMID:20044591
NCBI chr 5:107,610,489...107,932,485
Ensembl chr 5:107,610,416...107,933,109
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Vitamin K 3 analog results in increased expression of FOS mRNA; Vitamin K 3 results in increased expression of FOS mRNA
CTD
PMID:19273458
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
G
Foxa1
forkhead box A1
affects expression
ISO
Vitamin K 3 affects the expression of FOXA1 mRNA
CTD
PMID:20044591
NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
G
Foxa3
forkhead box A3
affects expression
ISO
Vitamin K 3 affects the expression of FOXA3 mRNA
CTD
PMID:20044591
NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:87,790,012...87,800,953
G
Foxc1
forkhead box C1
affects expression
ISO
Vitamin K 3 affects the expression of FOXC1 mRNA
CTD
PMID:20044591
NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347
G
Foxd2
forkhead box D2
affects expression
ISO
Vitamin K 3 affects the expression of FOXD2 mRNA
CTD
PMID:20044591
NCBI chr 5:133,664,760...133,667,483
Ensembl chr 5:133,664,760...133,667,483
G
Foxj3
forkhead box J3
affects expression
ISO
Vitamin K 3 affects the expression of FOXJ3 mRNA
CTD
PMID:20044591
NCBI chr 5:138,425,623...138,513,760
Ensembl chr 5:138,424,923...138,513,760
G
Foxm1
forkhead box M1
decreases expression
ISO
Vitamin K 3 results in decreased expression of FOXM1 mRNA
CTD
PMID:12414654
NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
G
Foxn3
forkhead box N3
affects expression
ISO
Vitamin K 3 affects the expression of CHES1 mRNA
CTD
PMID:20044591
NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040
G
Foxo1
forkhead box O1
affects expression
ISO
Vitamin K 3 affects the expression of FOXO1A mRNA
CTD
PMID:20044591
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
G
Foxp1
forkhead box P1
affects expression
ISO
Vitamin K 3 affects the expression of FOXP1 mRNA
CTD
PMID:20044591
NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272
G
Frmd4a
FERM domain containing 4A
affects expression
ISO
Vitamin K 3 affects the expression of FRMD4A mRNA
CTD
PMID:20044591
NCBI chr17:78,577,062...79,167,924
Ensembl chr17:78,579,277...79,167,663
G
Fshb
follicle stimulating hormone subunit beta
multiple interactions
EXP
Vitamin K 3 results in decreased expression of and results in decreased secretion of FSHB protein
CTD
PMID:30536483
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
G
Ftl1
ferritin light chain 1
affects expression increases expression multiple interactions
ISO
Vitamin K 3 affects the expression of FTL mRNA Vitamin K 3 results in increased expression of FTL mRNA Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
CTD
PMID:12414654 PMID:12644586 PMID:20044591
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
G
Ftmt
ferritin mitochondrial
multiple interactions
ISO
Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
CTD
PMID:12644586
NCBI chr18:47,957,235...47,958,484
Ensembl chr18:47,957,228...47,958,768
G
Fuom
fucose mutarotase
affects expression
ISO
Vitamin K 3 affects the expression of FUOM mRNA
CTD
PMID:20044591
NCBI chr 1:204,318,180...204,322,690
Ensembl chr 1:204,316,354...204,322,690
G
Fut1
fucosyltransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of FUT1 mRNA
CTD
PMID:20044591
NCBI chr 1:105,223,399...105,226,817
Ensembl chr 1:105,223,390...105,227,513
G
Fut8
fucosyltransferase 8
affects expression
ISO
Vitamin K 3 affects the expression of FUT8 mRNA
CTD
PMID:20044591
NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:101,683,007...101,909,775
G
Fzd4
frizzled class receptor 4
affects expression
ISO
Vitamin K 3 affects the expression of FZD4 mRNA
CTD
PMID:20044591
NCBI chr 1:152,692,507...152,701,372
Ensembl chr 1:152,692,507...152,701,372
G
Fzd7
frizzled class receptor 7
affects expression
ISO
Vitamin K 3 affects the expression of FZD7 mRNA
CTD
PMID:20044591
NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:68,411,259...68,432,585
G
G0s2
G0/G1switch 2
affects expression
ISO
Vitamin K 3 affects the expression of G0S2 mRNA
CTD
PMID:20044591
NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293
G
G2e3
G2/M-phase specific E3 ubiquitin protein ligase
decreases expression
ISO
Vitamin K 3 results in decreased expression of G2E3 mRNA
CTD
PMID:25270620
NCBI chr 6:74,498,801...74,530,703
Ensembl chr 6:74,503,109...74,528,198
G
Gaa
alpha glucosidase
affects expression
ISO
Vitamin K 3 affects the expression of GAA mRNA
CTD
PMID:20044591
NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
affects expression
ISO
Vitamin K 3 affects the expression of GADD45B mRNA
CTD
PMID:23410634
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718
G
Gal
galanin and GMAP prepropeptide
affects expression
ISO
Vitamin K 3 affects the expression of GAL mRNA
CTD
PMID:20044591
NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229
G
Gal3st1
galactose-3-O-sulfotransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of GAL3ST1 mRNA
CTD
PMID:20044591
NCBI chr14:83,094,265...83,109,992
Ensembl chr14:83,094,385...83,109,978
G
Galm
galactose mutarotase
affects expression
ISO
Vitamin K 3 affects the expression of GALM mRNA
CTD
PMID:20044591
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
G
Galnt11
polypeptide N-acetylgalactosaminyltransferase 11
affects expression
ISO
Vitamin K 3 affects the expression of GALNT11 mRNA
CTD
PMID:20044591
NCBI chr 4:10,571,464...10,604,974
Ensembl chr 4:10,571,464...10,604,974
G
Gap43
growth associated protein 43
increases expression
ISO
Vitamin K 3 analog results in increased expression of GAP43 mRNA
CTD
PMID:19273458
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
G
Gart
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
affects expression
ISO
Vitamin K 3 affects the expression of GART mRNA
CTD
PMID:20044591
NCBI chr11:44,351,841...44,377,086
Ensembl chr11:44,351,851...44,377,086
G
Gata6
GATA binding protein 6
affects expression
ISO
Vitamin K 3 affects the expression of GATA6 mRNA
CTD
PMID:20044591
NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases activity increases expression multiple interactions
ISO
Vitamin K 3 results in increased activity of GCLC protein Vitamin K 3 results in increased expression of GCLC mRNA Dactinomycin inhibits the reaction [Vitamin K 3 results in increased expression of GCLC mRNA]
CTD
PMID:11972604 PMID:23410634 PMID:25270620
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Vitamin K 3 results in increased expression of GCLM mRNA
CTD
PMID:12414654 PMID:23410634 PMID:25270620
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
G
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
increases expression
ISO
Vitamin K 3 results in increased expression of GCNT3 mRNA
CTD
PMID:23410634
NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595
G
Gdf15
growth differentiation factor 15
affects expression increases expression
ISO
Vitamin K 3 affects the expression of GDF15 mRNA Vitamin K 3 results in increased expression of GDF15 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
G
Gdi1
GDP dissociation inhibitor 1
affects expression
ISO
Vitamin K 3 affects the expression of GDI1 mRNA
CTD
PMID:20044591
NCBI chr X:157,238,900...157,245,562
Ensembl chr X:157,238,892...157,245,560
G
Gdi2
GDP dissociation inhibitor 2
affects expression
ISO
Vitamin K 3 affects the expression of GDI2 mRNA
CTD
PMID:20044591
NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147
G
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
affects expression
ISO
Vitamin K 3 affects the expression of GDPD5 mRNA
CTD
PMID:23410634
NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:163,091,833...163,173,559
G
Gemin6
gem (nuclear organelle) associated protein 6
affects expression
ISO
Vitamin K 3 affects the expression of GEMIN6 mRNA
CTD
PMID:20044591
NCBI chr 6:20,538,325...20,542,867
Ensembl chr 6:20,538,325...20,542,852
G
Ggt1
gamma-glutamyltransferase 1
decreases expression multiple interactions
EXP
Vitamin K 3 results in decreased expression of GGT1 mRNA alternative form Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Vitamin K 3 results in increased expression of and results in increased activity of GGT1 protein
CTD
PMID:12030384
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
G
Ghr
growth hormone receptor
affects expression
ISO
Vitamin K 3 affects the expression of GHR mRNA
CTD
PMID:20829426
NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
G
Gigyf2
GRB10 interacting GYF protein 2
affects expression
ISO
Vitamin K 3 affects the expression of GIGYF2 mRNA
CTD
PMID:20044591
NCBI chr 9:95,449,143...95,574,927
Ensembl chr 9:95,449,167...95,574,927
G
Gipc2
GIPC PDZ domain containing family, member 2
increases expression
ISO
Vitamin K 3 results in increased expression of GIPC2 mRNA
CTD
PMID:25270620
NCBI chr 2:243,690,742...243,770,199
Ensembl chr 2:243,690,748...243,770,199
G
Gja1
gap junction protein, alpha 1
affects expression
ISO
Vitamin K 3 affects the expression of GJA1 mRNA
CTD
PMID:20829426
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
G
Glcci1
glucocorticoid induced 1
affects expression
ISO
Vitamin K 3 affects the expression of GLCCI1 mRNA
CTD
PMID:20044591
NCBI chr 4:37,274,271...37,601,898
Ensembl chr 4:37,529,364...37,599,802 Ensembl chr 4:37,529,364...37,599,802
G
Gldc
glycine decarboxylase
affects expression
ISO
Vitamin K 3 affects the expression of GLDC mRNA
CTD
PMID:20044591
NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604
G
Glg1
golgi glycoprotein 1
affects expression
ISO
Vitamin K 3 affects the expression of GLG1 mRNA
CTD
PMID:20044591
NCBI chr19:56,034,248...56,133,538
Ensembl chr19:56,006,459...56,133,528
G
Glrx
glutaredoxin
increases expression
ISO
Vitamin K 3 results in increased expression of GLRX mRNA
CTD
PMID:12414654
NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543
G
Gls
glutaminase
affects expression
ISO
Vitamin K 3 affects the expression of GLS mRNA
CTD
PMID:20044591
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
G
Glt8d1
glycosyltransferase 8 domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of GLT8D1 mRNA
CTD
PMID:20044591
NCBI chr16:6,198,152...6,213,671
Ensembl chr16:6,204,740...6,213,668
G
Glyctk
glycerate kinase
affects expression
ISO
Vitamin K 3 affects the expression of GLYCTK mRNA
CTD
PMID:20044591
NCBI chr 8:115,676,071...115,681,403
Ensembl chr 8:115,676,072...115,681,091
G
Gnai1
G protein subunit alpha i1
affects expression
ISO
Vitamin K 3 affects the expression of GNAI1 mRNA
CTD
PMID:23410634
NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198
G
Gnaz
G protein subunit alpha z
affects expression
ISO
Vitamin K 3 affects the expression of GNAZ mRNA
CTD
PMID:20044591
NCBI chr20:13,642,853...13,693,616
Ensembl chr20:13,644,020...13,669,287
G
Gnpat
glyceronephosphate O-acyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of GNPAT mRNA
CTD
PMID:20044591
NCBI chr19:69,719,707...69,746,244
Ensembl chr19:69,719,394...69,746,244
G
Golga3
golgin A3
affects expression
ISO
Vitamin K 3 affects the expression of GOLGA3 mRNA
CTD
PMID:20044591
NCBI chr12:52,112,129...52,160,311
Ensembl chr12:52,114,590...52,160,226
G
Gon4l
gon-4 like
affects expression
ISO
Vitamin K 3 affects the expression of GON4L mRNA
CTD
PMID:20044591
NCBI chr 2:176,531,274...176,604,446
Ensembl chr 2:176,531,274...176,604,444
G
Gopc
golgi associated PDZ and coiled-coil motif containing
affects expression
ISO
Vitamin K 3 affects the expression of GOPC mRNA
CTD
PMID:20044591
NCBI chr20:32,270,314...32,319,635
Ensembl chr20:32,270,314...32,319,611
G
Gpank1
G patch domain and ankyrin repeats 1
affects expression
ISO
Vitamin K 3 affects the expression of GPANK1 mRNA
CTD
PMID:20044591
NCBI chr20:3,702,309...3,705,476
Ensembl chr20:3,702,309...3,705,306
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
Vitamin K 3 results in increased expression of GPAT3 mRNA
CTD
PMID:23410634
NCBI chr14:9,018,762...9,072,552
G
Gpbp1
GC-rich promoter binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of GPBP1 mRNA
CTD
PMID:20829426
NCBI chr 2:44,756,861...44,824,281
Ensembl chr 2:44,756,861...44,824,315
G
Gpr160
G protein-coupled receptor 160
affects expression
ISO
Vitamin K 3 affects the expression of GPR160 mRNA
CTD
PMID:20044591
NCBI chr 2:114,414,084...114,491,590
Ensembl chr 2:114,410,261...114,474,790
G
Gprc5a
G protein-coupled receptor, class C, group 5, member A
affects expression
ISO
Vitamin K 3 affects the expression of GPRC5A mRNA
CTD
PMID:20044591
NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:169,634,748...169,653,625
G
Gprc5b
G protein-coupled receptor, class C, group 5, member B
affects expression
ISO
Vitamin K 3 affects the expression of GPRC5B mRNA
CTD
PMID:20044591
NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757
G
Gprc5c
G protein-coupled receptor, class C, group 5, member C
affects expression
ISO
Vitamin K 3 affects the expression of GPRC5C mRNA
CTD
PMID:20044591
NCBI chr10:100,385,682...100,407,953
Ensembl chr10:100,383,631...100,426,962
G
Gpt2
glutamic--pyruvic transaminase 2
affects expression
ISO
Vitamin K 3 affects the expression of GPT2 mRNA
CTD
PMID:20044591
NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917
G
Gpx1
glutathione peroxidase 1
decreases response to substance
ISO
GPX1 protein results in decreased susceptibility to Vitamin K 3
CTD
PMID:1939125
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx2
glutathione peroxidase 2
increases expression
ISO
Vitamin K 3 results in increased expression of GPX2 mRNA
CTD
PMID:12414654
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
G
Grid1
glutamate ionotropic receptor delta type subunit 1
affects expression
ISO
Vitamin K 3 affects the expression of GRID1 mRNA
CTD
PMID:20044591
NCBI chr16:10,145,018...10,894,184
Ensembl chr16:10,144,964...10,891,946
G
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
increases expression
ISO
Vitamin K 3 results in increased expression of GRIN2C mRNA
CTD
PMID:12414654
NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,987,513...101,005,409
G
Grk5
G protein-coupled receptor kinase 5
affects expression
ISO
Vitamin K 3 affects the expression of GRK5 mRNA
CTD
PMID:20044591
NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928
G
Grn
granulin precursor
affects expression
ISO
Vitamin K 3 affects the expression of GRN mRNA
CTD
PMID:20044591
NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
G
Grwd1
glutamate-rich WD repeat containing 1
affects expression
ISO
Vitamin K 3 affects the expression of GRWD1 mRNA
CTD
PMID:20044591
NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825
G
Gsdme
gasdermin E
affects expression
ISO
Vitamin K 3 affects the expression of GSDME mRNA
CTD
PMID:20044591
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO
Vitamin K 3 results in increased expression of GSK3B protein
CTD
PMID:31238027
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
G
Gsn
gelsolin
affects response to substance
ISO
GSN mRNA affects the susceptibility to Vitamin K 3
CTD
PMID:14652020 PMID:15033777
NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
Vitamin K 3 results in increased expression of GSR mRNA
CTD
PMID:23410634
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
G
Gsta1
glutathione S-transferase alpha 1
affects expression
ISO
Vitamin K 3 affects the expression of GSTA1 mRNA
CTD
PMID:20044591
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
G
Gsta2
glutathione S-transferase alpha 2
affects expression
ISO
Vitamin K 3 affects the expression of GSTA2 mRNA
CTD
PMID:20044591
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
G
Gsta4
glutathione S-transferase alpha 4
affects expression
ISO
Vitamin K 3 affects the expression of GSTA4 mRNA
CTD
PMID:20044591
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
G
Gsta5
glutathione S-transferase alpha 5
affects expression
ISO
Vitamin K 3 affects the expression of GSTA5 mRNA
CTD
PMID:20044591 PMID:20829426
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
G
Gstm1
glutathione S-transferase mu 1
increases expression
ISO
Vitamin K 3 results in increased expression of GSTM1 mRNA
CTD
PMID:14610226
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
G
Gsto1
glutathione S-transferase omega 1
affects expression
ISO
Vitamin K 3 affects the expression of GSTO1 mRNA
CTD
PMID:20044591
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
G
Gtf2i
general transcription factor II I
affects expression
ISO
Vitamin K 3 affects the expression of GTF2I mRNA
CTD
PMID:20044591
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
G
Gtf3c2
general transcription factor IIIC subunit 2
affects expression
ISO
Vitamin K 3 affects the expression of GTF3C2 mRNA
CTD
PMID:20044591
NCBI chr 6:30,913,263...30,941,305
Ensembl chr 6:30,923,106...30,940,465
G
Gtpbp3
GTP binding protein 3
affects expression
ISO
Vitamin K 3 affects the expression of GTPBP3 mRNA
CTD
PMID:20044591
NCBI chr16:18,209,747...18,214,838
Ensembl chr16:18,209,682...18,214,838
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Gtpbp4
GTP binding protein 4
affects expression
ISO
Vitamin K 3 affects the expression of GTPBP4 mRNA
CTD
PMID:20044591
NCBI chr17:65,997,472...66,019,530
Ensembl chr17:66,276,566...66,289,637
G
Gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
decreases expression
EXP
Vitamin K 3 results in decreased expression of GUCY1A1 protein
CTD
PMID:17339839
NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737
G
Gucy1b1
guanylate cyclase 1 soluble subunit beta 1
decreases expression
EXP
Vitamin K 3 results in decreased expression of GUCY1B1 protein
CTD
PMID:17339839
NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987
G
Gucy2c
guanylate cyclase 2C
affects expression
ISO
Vitamin K 3 affects the expression of GUCY2C mRNA
CTD
PMID:20044591
NCBI chr 4:171,299,715...171,380,296
Ensembl chr 4:171,299,740...171,380,296
G
Gusb
glucuronidase, beta
affects expression
ISO
Vitamin K 3 affects the expression of GUSB mRNA
CTD
PMID:20044591
NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024
G
H1f4
H1.4 linker histone, cluster member
affects expression
ISO
Vitamin K 3 affects the expression of H1-4 mRNA
CTD
PMID:20044591
NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129
G
H1f5
H1.5 linker histone, cluster member
affects expression
ISO
Vitamin K 3 affects the expression of H1-5 mRNA
CTD
PMID:20044591
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
G
H2ac13
H2A clustered histone 13
affects expression
ISO
Vitamin K 3 affects the expression of H2AC8 mRNA
CTD
PMID:20044591
NCBI chr17:41,807,261...41,807,653
G
H2ac18
H2A clustered histone 18
affects expression
ISO
Vitamin K 3 affects the expression of H2AC18 mRNA
CTD
PMID:20044591
NCBI chr 2:186,497,271...186,497,865
G
H2ac20
H2A clustered histone 20
affects expression
ISO
Vitamin K 3 affects the expression of H2AC20 mRNA
CTD
PMID:20044591
NCBI chr 2:186,468,748...186,469,226
G
H2ac25
H2A clustered histone 25
affects expression
ISO
Vitamin K 3 affects the expression of H2AC25 mRNA
CTD
PMID:20044591
NCBI chr10:44,233,283...44,234,835
Ensembl chr10:44,233,181...44,241,197
G
H2aj
H2A.J histone
affects expression
ISO
Vitamin K 3 affects the expression of H2AJ mRNA
CTD
PMID:20044591
NCBI chr 4:171,406,922...171,407,406
Ensembl chr 4:171,406,177...171,408,845
G
H2ax
H2A.X variant histone
multiple interactions
ISO
[Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation of H2AX protein
CTD
PMID:19482829
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
G
H2bc27
H2B clustered histone 27
affects expression
ISO
Vitamin K 3 affects the expression of H2BC26 mRNA
CTD
PMID:20044591
NCBI chr10:44,232,318...44,233,065
Ensembl chr10:44,232,318...44,233,065
G
H2bc3
H2B clustered histone 3
affects expression
ISO
Vitamin K 3 affects the expression of H2BC3 mRNA
CTD
PMID:20044591
NCBI chr17:41,807,913...41,808,543
G
H2bc6
H2B clustered histone 6
affects expression
ISO
Vitamin K 3 affects the expression of H2BC6 mRNA
CTD
PMID:20044591
NCBI chr17:41,948,813...41,949,276
Ensembl chr17:47,392,229...47,449,312
G
H2bc9
H2B clustered histone 9
affects expression
ISO
Vitamin K 3 affects the expression of H2BC9 mRNA
CTD
PMID:20044591
NCBI chr17:47,166,372...47,174,369
G
H4c1
H4 clustered histone 1
affects expression
ISO
Vitamin K 3 affects the expression of H4C1 mRNA
CTD
PMID:20044591
NCBI chr17:47,393,764...47,394,168
Ensembl chr17:47,393,603...47,453,972 Ensembl chr17:47,393,603...47,453,972 Ensembl chr 4:47,393,603...47,453,972 Ensembl chr17:47,393,603...47,453,972 Ensembl chr17:47,393,603...47,453,972
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Hadh
hydroxyacyl-CoA dehydrogenase
affects expression
ISO
Vitamin K 3 affects the expression of HADH mRNA
CTD
PMID:20044591
NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
G
Hamp
hepcidin antimicrobial peptide
affects expression
ISO
Vitamin K 3 affects the expression of HAMP mRNA
CTD
PMID:23410634
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
G
Hars2
histidyl-tRNA synthetase 2, mitochondrial
affects expression
ISO
Vitamin K 3 affects the expression of HARS2 mRNA
CTD
PMID:20044591
NCBI chr18:28,672,810...28,682,367
Ensembl chr18:28,672,824...28,682,359
G
Havcr1
hepatitis A virus cellular receptor 1
affects expression
ISO
Vitamin K 3 affects the expression of HAVCR1 mRNA
CTD
PMID:20044591
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
G
Hba-a3
hemoglobin alpha, adult chain 3
affects expression
ISO
Vitamin K 3 affects the expression of HBA2 mRNA
CTD
PMID:20044591
NCBI chr10:15,816,099...15,816,943
Ensembl chr10:15,816,096...15,817,167
G
Hbp1
HMG-box transcription factor 1
affects expression
ISO
Vitamin K 3 affects the expression of HBP1 mRNA
CTD
PMID:20044591
NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:54,256,864...54,283,366
G
Hcar1
hydroxycarboxylic acid receptor 1
affects expression
ISO
Vitamin K 3 affects the expression of HCAR1 mRNA
CTD
PMID:20044591
NCBI chr12:38,371,593...38,374,847
Ensembl chr12:38,371,374...38,407,284
G
Hccs
holocytochrome c synthase
affects expression
ISO
Vitamin K 3 affects the expression of HCCS mRNA
CTD
PMID:20044591
NCBI chr X:28,505,370...28,514,812
Ensembl chr X:28,505,417...28,514,812
G
Hcfc1r1
host cell factor C1 regulator 1
affects expression
ISO
Vitamin K 3 affects the expression of HCFC1R1 mRNA
CTD
PMID:20044591
NCBI chr10:13,209,757...13,211,445
Ensembl chr10:13,209,558...13,211,443
G
Hdac11
histone deacetylase 11
affects expression
ISO
Vitamin K 3 affects the expression of HDAC11 mRNA
CTD
PMID:23410634
NCBI chr 4:125,203,044...125,224,584
Ensembl chr 4:125,202,299...125,224,582
G
Hdac2
histone deacetylase 2
affects expression
ISO
Vitamin K 3 affects the expression of HDAC2 mRNA
CTD
PMID:20044591
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311
G
Heatr1
HEAT repeat containing 1
affects expression
ISO
Vitamin K 3 affects the expression of HEATR1 mRNA
CTD
PMID:20044591
NCBI chr17:62,745,008...62,785,609
Ensembl chr17:62,745,008...62,785,186
G
Heca
hdc homolog, cell cycle regulator
affects expression
ISO
Vitamin K 3 affects the expression of HECA mRNA
CTD
PMID:20044591
NCBI chr 1:14,345,306...14,395,226
Ensembl chr 1:14,345,306...14,395,191
G
Heph
hephaestin
affects expression
ISO
Vitamin K 3 affects the expression of HEPH mRNA
CTD
PMID:20044591
NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453
G
Herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
affects expression
ISO
Vitamin K 3 affects the expression of HERC2 mRNA
CTD
PMID:20044591
NCBI chr 1:116,009,681...116,243,888
Ensembl chr 1:116,040,736...116,243,884
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
affects expression
ISO
Vitamin K 3 affects the expression of HERPUD1 mRNA
CTD
PMID:20044591
NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081
G
Hes1
hes family bHLH transcription factor 1
affects expression increases expression multiple interactions
ISO
Vitamin K 3 affects the expression of HES1 mRNA Vitamin K 3 results in increased expression of HES1 protein EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of HES1 protein]
CTD
PMID:20044591 PMID:25005833
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
G
Hes6
hes family bHLH transcription factor 6
affects expression
ISO
Vitamin K 3 affects the expression of HES6 mRNA
CTD
PMID:23410634
NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096
G
Hgsnat
heparan-alpha-glucosaminide N-acetyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of HGSNAT mRNA
CTD
PMID:20044591
NCBI chr16:72,807,967...72,840,180
Ensembl chr16:72,807,849...72,840,176
G
Hibadh
3-hydroxyisobutyrate dehydrogenase
affects expression
ISO
Vitamin K 3 affects the expression of HIBADH mRNA
CTD
PMID:20044591
NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases expression multiple interactions
ISO EXP
Vitamin K 3 results in increased expression of HIF1A mRNA; Vitamin K 3 results in increased expression of HIF1A protein Vitamin K 3 inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]; Vitamin K 3 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Vitamin K 3 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD
PMID:12595275 PMID:16507596
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
G
Hif3a
hypoxia inducible factor 3 subunit alpha
affects expression
ISO
Vitamin K 3 affects the expression of HIF3A mRNA
CTD
PMID:20044591
NCBI chr 1:86,846,196...86,878,527
Ensembl chr 1:86,850,554...86,877,838
G
Hipk2
homeodomain interacting protein kinase 2
affects expression
ISO
Vitamin K 3 affects the expression of HIPK2 mRNA
CTD
PMID:20044591
NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:68,369,099...68,586,108
G
Hist1h2bq
histone cluster 1 H2B family member Q
affects expression
ISO
Vitamin K 3 affects the expression of H2BC7 mRNA
CTD
PMID:20044591
NCBI chr17:41,859,955...41,869,889
Ensembl chr17:41,857,231...41,870,107 Ensembl chr17:41,857,231...41,870,107
G
Hlcs
holocarboxylase synthetase
affects expression
ISO
Vitamin K 3 affects the expression of HLCS mRNA
CTD
PMID:20044591
NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082
G
Hmbox1
homeobox containing 1
affects expression
ISO
Vitamin K 3 affects the expression of HMBOX1 mRNA
CTD
PMID:20044591
NCBI chr15:43,243,503...43,376,011
Ensembl chr15:43,222,470...43,376,011
G
Hmgb3
high mobility group box 3
affects expression
ISO
Vitamin K 3 affects the expression of HMGB3 mRNA
CTD
PMID:20044591
NCBI chr X:154,341,106...154,346,087
Ensembl chr X:154,340,935...154,346,097
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression multiple interactions decreases activity
ISO
Vitamin K 3 results in increased expression of HMGCR mRNA manganese protoporphyrin inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein]
CTD
PMID:12414654 PMID:21257924
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
affects expression
ISO
Vitamin K 3 affects the expression of HMGCS2 mRNA
CTD
PMID:20044591
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
G
Hmox1
heme oxygenase 1
increases expression
EXP ISO
Vitamin K 3 results in increased expression of HMOX1 mRNA
CTD
PMID:12414654 PMID:19386027 PMID:23410634
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hnmt
histamine N-methyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of HNMT mRNA
CTD
PMID:20044591
NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482
G
Hoxd1
homeo box D1
affects expression
ISO
Vitamin K 3 affects the expression of HOXD1 mRNA
CTD
PMID:23410634
NCBI chr 3:80,073,041...80,075,180
Ensembl chr 3:80,073,041...80,075,180
G
Hp
haptoglobin
affects expression
ISO
Vitamin K 3 affects the expression of HP mRNA
CTD
PMID:20044591
NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518
G
Hsbp1
heat shock factor binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of HSBP1 mRNA
CTD
PMID:20044591
NCBI chr19:64,309,703...64,314,035
Ensembl chr19:64,309,703...64,314,035
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
affects expression
ISO
Vitamin K 3 affects the expression of HSD11B2 mRNA
CTD
PMID:23410634
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
G
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
affects expression
ISO
Vitamin K 3 affects the expression of HSD17B11 mRNA
CTD
PMID:20044591
NCBI chr14:5,997,893...6,047,816
Ensembl chr14:5,997,906...6,047,811
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
ISO
Vitamin K 3 affects the expression of HSD17B4 mRNA
CTD
PMID:20044591
NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
affects expression multiple interactions
ISO
Vitamin K 3 affects the expression of HSD3B1 mRNA [Vitamin K 3 co-treated with NADP] binds to HSD3B1 protein
CTD
PMID:20044591 PMID:25526675
NCBI chr 2:188,858,574...188,864,694
G
Hsf1
heat shock transcription factor 1
increases activity
ISO
Vitamin K 3 results in increased activity of HSF1 protein
CTD
PMID:34170685
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
G
Hsp90b1
heat shock protein 90 beta family member 1
affects expression
ISO
Vitamin K 3 affects the expression of HSP90B1 mRNA
CTD
PMID:20829426
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
affects expression increases expression
ISO
Vitamin K 3 affects the expression of HSPA1A mRNA Vitamin K 3 results in increased expression of HSPA1A mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Vitamin K 3 results in increased expression of HSPA1B mRNA
CTD
PMID:12414654
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases expression
ISO
Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein]
CTD
PMID:19819344
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
Vitamin K 3 results in increased expression of HSPA6 mRNA
CTD
PMID:12414654
NCBI chr13:85,805,911...85,807,052
G
Hspb1
heat shock protein family B (small) member 1
affects expression
ISO
Vitamin K 3 affects the expression of HSPB1 mRNA
CTD
PMID:20044591
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
Vitamin K 3 results in increased expression of HTATIP2 mRNA
CTD
PMID:25270620
NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815
G
Iars1
isoleucyl-tRNA synthetase 1
affects expression
ISO
Vitamin K 3 affects the expression of IARS1 mRNA
CTD
PMID:20044591
NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652
G
Ica1
islet cell autoantigen 1
affects expression
ISO
Vitamin K 3 affects the expression of ICA1 mRNA
CTD
PMID:20044591
NCBI chr 4:37,622,759...37,771,055
Ensembl chr 4:37,622,759...37,770,569
G
Icoslg
inducible T-cell co-stimulator ligand
decreases expression
ISO
Vitamin K 3 results in decreased expression of ICOSL mRNA
CTD
PMID:25270620
NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,078...10,610,365
G
Id1
inhibitor of DNA binding 1
affects expression
ISO
Vitamin K 3 affects the expression of ID1 mRNA
CTD
PMID:20044591
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
G
Ier5
immediate early response 5
affects expression
ISO
Vitamin K 3 affects the expression of IER5 mRNA
CTD
PMID:20044591
NCBI chr13:69,820,450...69,822,542
Ensembl chr13:69,820,451...69,822,543
G
Ifi30
IFI30, lysosomal thiol reductase
affects expression
ISO
Vitamin K 3 affects the expression of IFI30 mRNA
CTD
PMID:20044591
NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711
G
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
affects expression
ISO
Vitamin K 3 affects the expression of IFIT3 mRNA
CTD
PMID:20829426
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
G
Ift22
intraflagellar transport 22
affects expression
ISO
Vitamin K 3 affects the expression of IFT22 mRNA
CTD
PMID:20044591
NCBI chr12:25,397,092...25,405,522
Ensembl chr12:25,387,347...25,405,510
G
Igf1r
insulin-like growth factor 1 receptor
affects expression
ISO
Vitamin K 3 affects the expression of IGF1R mRNA
CTD
PMID:20044591
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
G
Igf2r
insulin-like growth factor 2 receptor
affects expression
ISO
Vitamin K 3 affects the expression of IGF2R mRNA
CTD
PMID:20044591
NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265
G
Igfbp2
insulin-like growth factor binding protein 2
decreases expression
ISO
Vitamin K 3 results in decreased expression of IGFBP2 mRNA
CTD
PMID:25270620
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
G
Igfbp5
insulin-like growth factor binding protein 5
increases expression
ISO
Vitamin K 3 results in increased expression of IGFBP5 mRNA
CTD
PMID:12414654
NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
G
Il11
interleukin 11
affects expression
ISO
Vitamin K 3 affects the expression of IL11 mRNA
CTD
PMID:23410634
NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
G
Il1a
interleukin 1 alpha
multiple interactions increases secretion increases expression
EXP ISO
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein] [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3
CTD
PMID:19265712 PMID:19362101
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
G
Il1b
interleukin 1 beta
multiple interactions increases expression increases secretion
EXP
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1B mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1B protein]
CTD
PMID:19265712
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3
CTD
PMID:19362101
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Ilf2
interleukin enhancer binding factor 2
affects expression
ISO
Vitamin K 3 affects the expression of ILF2 mRNA
CTD
PMID:20044591
NCBI chr 2:178,256,927...178,268,773
Ensembl chr 2:178,248,585...178,268,920
G
Inhbb
inhibin subunit beta B
affects expression increases expression
ISO
Vitamin K 3 affects the expression of INHBB mRNA Vitamin K 3 results in increased expression of INHBB mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609
G
Insig2
insulin induced gene 2
affects expression
ISO
Vitamin K 3 affects the expression of INSIG2 mRNA
CTD
PMID:20044591
NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658
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Ints10
integrator complex subunit 10
affects expression
ISO
Vitamin K 3 affects the expression of INTS10 mRNA
CTD
PMID:20044591
NCBI chr16:25,682,818...25,735,840
Ensembl chr16:25,682,050...25,734,528
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Ipo7
importin 7
affects expression
ISO
Vitamin K 3 affects the expression of IPO7 mRNA
CTD
PMID:20044591
NCBI chr 1:173,497,472...173,537,707
Ensembl chr 1:173,497,503...173,536,778
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Irf2bp2
interferon regulatory factor 2 binding protein 2
affects expression
ISO
Vitamin K 3 affects the expression of IRF2BP2 mRNA
CTD
PMID:20044591
NCBI chr19:71,456,689...71,462,368
Ensembl chr19:71,456,689...71,462,368
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Irf5
interferon regulatory factor 5
affects expression
ISO
Vitamin K 3 affects the expression of IRF5 mRNA
CTD
PMID:20044591
NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:59,081,357...59,112,552
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Irx5
iroquois homeobox 5
affects expression
ISO
Vitamin K 3 affects the expression of IRX5 mRNA
CTD
PMID:20044591
NCBI chr19:30,812,033...30,816,885
Ensembl chr19:30,797,202...30,815,029
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Isg20
interferon stimulated exonuclease gene 20
affects expression
ISO
Vitamin K 3 affects the expression of ISG20 mRNA
CTD
PMID:20044591
NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
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Isg20l2
interferon stimulated exonuclease gene 20-like 2
affects expression
ISO
Vitamin K 3 affects the expression of ISG20L2 mRNA
CTD
PMID:20044591
NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095
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Itga4
integrin subunit alpha 4
affects expression
ISO
Vitamin K 3 affects the expression of ITGA4 mRNA
CTD
PMID:20829426
NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039
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Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
affects expression
ISO
Vitamin K 3 affects the expression of ITPR3 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184
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Itprid2
ITPR interacting domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of ITPRID2 mRNA
CTD
PMID:20044591
NCBI chr 3:84,943,572...84,980,993
Ensembl chr 3:84,939,808...84,980,899
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Jag1
jagged canonical Notch ligand 1
affects expression
ISO
Vitamin K 3 affects the expression of JAG1 mRNA
CTD
PMID:20044591
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872
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Jak1
Janus kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of JAK1 mRNA
CTD
PMID:20829426
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
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Jak3
Janus kinase 3
multiple interactions increases phosphorylation
ISO
[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; [Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein; JAK3 protein promotes the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]
CTD
PMID:24106086
NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
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Jaml
junction adhesion molecule like
affects expression
ISO
Vitamin K 3 affects the expression of JAML mRNA
CTD
PMID:20044591
NCBI chr 8:54,281,596...54,313,655
Ensembl chr 8:54,281,644...54,313,500
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Jarid2
jumonji and AT-rich interaction domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of JARID2 mRNA
CTD
PMID:20044591
NCBI chr17:19,983,217...20,163,598
Ensembl chr17:19,983,217...20,161,970
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Vitamin K 3 results in increased expression of JUN mRNA
CTD
PMID:12414654
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Kank1
KN motif and ankyrin repeat domains 1
affects expression
ISO
Vitamin K 3 affects the expression of KANK1 mRNA
CTD
PMID:20044591
NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839
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Kat2a
lysine acetyltransferase 2A
affects expression
ISO
Vitamin K 3 affects the expression of KAT2A mRNA
CTD
PMID:23410634
NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485
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Kazald1
Kazal-type serine peptidase inhibitor domain 1
affects expression
ISO
Vitamin K 3 affects the expression of KAZALD1 mRNA
CTD
PMID:20044591
NCBI chr 1:253,888,639...253,892,211
Ensembl chr 1:253,888,783...253,892,305
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Kbtbd11
kelch repeat and BTB domain containing 11
affects expression
ISO
Vitamin K 3 affects the expression of KBTBD11 mRNA
CTD
PMID:20044591
NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390
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Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
affects expression
ISO
Vitamin K 3 affects the expression of KCNJ14 mRNA
CTD
PMID:20044591
NCBI chr 1:105,429,607...105,437,258
Ensembl chr 1:105,429,883...105,433,892 Ensembl chr 1:105,429,883...105,433,892
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Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
affects expression
ISO
Vitamin K 3 affects the expression of KCNJ16 mRNA
CTD
PMID:20044591
NCBI chr10:96,489,329...96,520,745
Ensembl chr10:96,460,331...96,566,075
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Kcnn4
potassium calcium-activated channel subfamily N member 4
affects expression
ISO
Vitamin K 3 affects the expression of KCNN4 mRNA
CTD
PMID:20044591
NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275
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Kctd10
potassium channel tetramerization domain containing 10
affects expression
ISO
Vitamin K 3 affects the expression of KCTD10 mRNA
CTD
PMID:20044591
NCBI chr12:47,890,777...47,909,391
Ensembl chr12:47,890,819...47,909,390
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Kctd21
potassium channel tetramerization domain containing 21
affects expression
ISO
Vitamin K 3 affects the expression of KCTD21 mRNA
CTD
PMID:23410634
NCBI chr 1:161,061,318...161,081,002
Ensembl chr 1:161,054,045...161,088,271
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Kdm2b
lysine demethylase 2B
affects expression
ISO
Vitamin K 3 affects the expression of KDM2B mRNA
CTD
PMID:20044591
NCBI chr12:39,224,422...39,362,126
Ensembl chr12:39,235,301...39,362,127
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Kdm3a
lysine demethylase 3A
affects expression
ISO
Vitamin K 3 affects the expression of KDM3A mRNA
CTD
PMID:23410634
NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370
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Kdm3b
lysine demethylase 3B
affects expression
ISO
Vitamin K 3 affects the expression of KDM3B mRNA
CTD
PMID:20044591
NCBI chr18:26,655,004...26,710,814
Ensembl chr18:26,655,687...26,710,814
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Keap1
Kelch-like ECH-associated protein 1
multiple interactions decreases expression
ISO
[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3 Vitamin K 3 results in decreased expression of KEAP1 mRNA
CTD
PMID:19608619 PMID:23410634
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
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Khdrbs1
KH RNA binding domain containing, signal transduction associated 1
affects expression
ISO
Vitamin K 3 affects the expression of KHDRBS1 mRNA
CTD
PMID:20044591
NCBI chr 5:147,337,048...147,374,604
Ensembl chr 5:147,347,904...147,373,448
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Kiaa1549
KIAA1549 homolog
affects expression
ISO
Vitamin K 3 affects the expression of KIAA1549 mRNA
CTD
PMID:20044591
NCBI chr 4:67,807,635...67,935,303
Ensembl chr 4:67,811,803...67,935,360
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Kif13b
kinesin family member 13B
affects expression
ISO
Vitamin K 3 affects the expression of KIF13B mRNA
CTD
PMID:20044591
NCBI chr15:43,084,059...43,241,719
Ensembl chr15:43,080,910...43,241,719
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Kif15
kinesin family member 15
affects expression
ISO
Vitamin K 3 affects the expression of KIF15 mRNA
CTD
PMID:23410634
NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202
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Kif1b
kinesin family member 1B
affects expression
ISO
Vitamin K 3 affects the expression of KIF1B mRNA
CTD
PMID:20044591
NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:164,894,763...165,008,841
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Kif23
kinesin family member 23
affects expression
ISO
Vitamin K 3 affects the expression of KIF23 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856
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Kif2c
kinesin family member 2C
affects expression
ISO
Vitamin K 3 affects the expression of KIF2C mRNA
CTD
PMID:20044591
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
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Kiss1r
KISS1 receptor
affects expression
ISO
Vitamin K 3 affects the expression of KISS1R mRNA
CTD
PMID:23410634
NCBI chr 7:10,435,766...10,439,424
Ensembl chr 7:10,435,766...10,439,424
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Klf10
KLF transcription factor 10
affects expression
ISO
Vitamin K 3 affects the expression of KLF10 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
G
Klf11
KLF transcription factor 11
affects expression
ISO
Vitamin K 3 affects the expression of KLF11 mRNA
CTD
PMID:20044591
NCBI chr 6:47,014,312...47,026,152
Ensembl chr 6:47,014,326...47,037,044
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Klf6
KLF transcription factor 6
affects expression increases expression multiple interactions
ISO
Vitamin K 3 affects the expression of KLF6 mRNA Vitamin K 3 results in increased expression of KLF6 mRNA; Vitamin K 3 results in increased expression of KLF6 mRNA alternative form; Vitamin K 3 results in increased expression of KLF6 protein [Arachidonic Acid co-treated with Vitamin K 3] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein; Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]
CTD
PMID:20044591 PMID:22486562
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
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Kng1
kininogen 1
affects expression
ISO
Vitamin K 3 affects the expression of KNG1 mRNA
CTD
PMID:20044591
NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148
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Kpnb1
karyopherin subunit beta 1
affects expression
ISO
Vitamin K 3 affects the expression of KPNB1 mRNA
CTD
PMID:20044591
NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,642,082...82,670,856
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Kri1
KRI1 homolog
affects expression
ISO
Vitamin K 3 affects the expression of KRI1 mRNA
CTD
PMID:20044591
NCBI chr 8:28,093,175...28,107,576
Ensembl chr 8:28,093,175...28,107,557
G
Krt10
keratin 10
affects expression
ISO
Vitamin K 3 affects the expression of KRT10 mRNA
CTD
PMID:20044591
NCBI chr10:84,834,865...84,839,160
Ensembl chr10:84,834,840...84,839,160
G
Krt23
keratin 23
affects expression
ISO
Vitamin K 3 affects the expression of KRT23 mRNA
CTD
PMID:20044591
NCBI chr10:84,930,603...84,946,929
Ensembl chr10:84,930,603...84,946,929
G
Krt8
keratin 8
multiple interactions increases phosphorylation
ISO
Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]
CTD
PMID:15939799
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
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Kynu
kynureninase
affects expression
ISO
Vitamin K 3 affects the expression of KYNU mRNA
CTD
PMID:20044591
NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
G
Lama5
laminin subunit alpha 5
affects expression
ISO
Vitamin K 3 affects the expression of LAMA5 mRNA
CTD
PMID:20044591
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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Lamb2
laminin subunit beta 2
affects expression
ISO
Vitamin K 3 affects the expression of LAMB2 mRNA
CTD
PMID:20044591
NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090
G
Lamc1
laminin subunit gamma 1
affects expression
ISO
Vitamin K 3 affects the expression of LAMC1 mRNA
CTD
PMID:20044591
NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986
G
Lamtor2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
affects expression
ISO
Vitamin K 3 affects the expression of LAMTOR2 mRNA
CTD
PMID:20044591
NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:176,306,280...176,310,730
G
Large1
LARGE xylosyl- and glucuronyltransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of LARGE1 mRNA
CTD
PMID:20044591
NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,609,004...12,054,707
G
Larp1b
La ribonucleoprotein 1B
affects expression
ISO
Vitamin K 3 affects the expression of LARP1B mRNA
CTD
PMID:20044591
NCBI chr 2:125,860,935...125,897,189
Ensembl chr 2:125,863,997...125,897,189
G
Larp6
La ribonucleoprotein 6, translational regulator
affects expression
ISO
Vitamin K 3 affects the expression of LARP6 mRNA
CTD
PMID:20044591
NCBI chr 8:70,079,753...70,101,175
Ensembl chr 8:70,079,647...70,101,198
G
Las1l
LAS1-like, ribosome biogenesis factor
affects expression
ISO
Vitamin K 3 affects the expression of LAS1L mRNA
CTD
PMID:20044591
NCBI chr X:64,861,472...64,883,221
Ensembl chr X:64,861,258...64,883,308
G
Lats2
large tumor suppressor kinase 2
affects expression
ISO
Vitamin K 3 affects the expression of LATS2 mRNA
CTD
PMID:20044591
NCBI chr15:35,940,632...35,992,225
Ensembl chr15:35,940,632...35,980,842
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Lbp
lipopolysaccharide binding protein
affects expression
ISO
Vitamin K 3 affects the expression of LBP mRNA
CTD
PMID:20829426
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
G
Lbr
lamin B receptor
decreases expression
ISO
Vitamin K 3 results in decreased expression of LBR mRNA
CTD
PMID:12414654
NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709
G
Ldha
lactate dehydrogenase A
affects expression
ISO
Vitamin K 3 affects the expression of LDHA mRNA
CTD
PMID:20044591
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
G
Ldhd
lactate dehydrogenase D
affects expression
ISO
Vitamin K 3 affects the expression of LDHD mRNA
CTD
PMID:20044591
NCBI chr19:56,492,827...56,497,695
Ensembl chr19:56,482,924...56,509,197
G
Ldlr
low density lipoprotein receptor
increases expression
ISO
Vitamin K 3 results in increased expression of LDLR mRNA
CTD
PMID:12414654
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
G
Lef1
lymphoid enhancer binding factor 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of LEF1 mRNA
CTD
PMID:25270620
NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929
G
Leo1
LEO1 homolog, Paf1/RNA polymerase II complex component
affects expression
ISO
Vitamin K 3 affects the expression of LEO1 mRNA
CTD
PMID:20044591
NCBI chr 8:85,080,036...85,104,471
Ensembl chr 8:85,079,996...85,105,094
G
Lep
leptin
multiple interactions increases expression
ISO
1,2-linoleoylphosphatidylcholine inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; S-Adenosylmethionine inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; SB 203580 inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]
CTD
PMID:16996477
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
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Leprot
leptin receptor overlapping transcript
affects expression
ISO
Vitamin K 3 affects the expression of LEPROT mRNA
CTD
PMID:20044591
NCBI chr 5:121,405,170...121,417,273
Ensembl chr 5:121,404,759...121,417,275
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Lgals8
galectin 8
affects expression
ISO
Vitamin K 3 affects the expression of LGALS8 mRNA
CTD
PMID:20044591
NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482
G
Lgr5
leucine rich repeat containing G protein coupled receptor 5
affects expression
ISO
Vitamin K 3 affects the expression of LGR5 mRNA
CTD
PMID:23410634
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
G
Lgsn
lengsin, lens protein with glutamine synthetase domain
affects expression
ISO
Vitamin K 3 affects the expression of LGSN mRNA
CTD
PMID:20044591
NCBI chr 9:40,912,398...40,943,955
Ensembl chr 9:40,916,520...40,943,943
G
Lhb
luteinizing hormone subunit beta
multiple interactions
EXP
Vitamin K 3 results in decreased expression of and results in decreased secretion of LHB protein
CTD
PMID:30536483
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
G
Lhx6
LIM homeobox 6
affects expression
ISO
Vitamin K 3 affects the expression of LHX6 mRNA
CTD
PMID:20044591
NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559
G
Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
Vitamin K 3 results in increased expression of LIF mRNA
CTD
PMID:12414654 PMID:23410634
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053
G
Lmbr1
limb development membrane protein 1
affects expression
ISO
Vitamin K 3 affects the expression of LMBR1 mRNA
CTD
PMID:23410634
NCBI chr 4:6,649,824...6,820,525
Ensembl chr 4:6,649,821...6,822,238
G
Lmcd1
LIM and cysteine-rich domains 1
affects expression
ISO
Vitamin K 3 affects the expression of LMCD1 mRNA
CTD
PMID:20044591
NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875
G
Lmnb1
lamin B1
affects expression
ISO
Vitamin K 3 affects the expression of LMNB1 mRNA
CTD
PMID:20044591
NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283
G
Lonp1
lon peptidase 1, mitochondrial
affects expression
ISO
Vitamin K 3 affects the expression of LONP1 mRNA
CTD
PMID:20044591
NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,534,584...1,547,427
G
Lox
lysyl oxidase
affects expression
ISO
Vitamin K 3 affects the expression of LOX mRNA
CTD
PMID:23410634
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
G
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
affects expression
ISO
Vitamin K 3 affects the expression of LRFN3 mRNA
CTD
PMID:20044591
NCBI chr 1:94,744,315...94,751,001
Ensembl chr 1:94,744,321...94,751,178
G
Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
affects expression
ISO
Vitamin K 3 affects the expression of LRIG1 mRNA
CTD
PMID:20044591
NCBI chr 4:128,687,723...128,788,219
Ensembl chr 4:128,687,723...128,788,219
G
Lrp1
LDL receptor related protein 1
affects expression
ISO
Vitamin K 3 affects the expression of LRP1 mRNA
CTD
PMID:23410634
NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
G
Lrp6
LDL receptor related protein 6
increases expression
ISO
Vitamin K 3 results in increased expression of LRP6 mRNA
CTD
PMID:12414654
NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716
G
Lrrc8e
leucine rich repeat containing 8 VRAC subunit E
affects expression
ISO
Vitamin K 3 affects the expression of LRRC8E mRNA
CTD
PMID:20044591
NCBI chr12:7,376,103...7,387,250
Ensembl chr12:7,380,585...7,387,249
G
Lrwd1
leucine-rich repeats and WD repeat domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of LRWD1 mRNA
CTD
PMID:20044591
NCBI chr12:26,166,648...26,179,689
Ensembl chr12:26,166,648...26,185,200
G
Lsm14a
LSM14A mRNA processing body assembly factor
affects expression
ISO
Vitamin K 3 affects the expression of LSM14A mRNA
CTD
PMID:20044591
NCBI chr 1:96,101,990...96,146,578
Ensembl chr 1:96,101,992...96,146,448
G
Lta4h
leukotriene A4 hydrolase
affects expression
ISO
Vitamin K 3 affects the expression of LTA4H mRNA
CTD
PMID:20044591
NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641
G
Ltv1
LTV1 ribosome biogenesis factor
affects expression
ISO
Vitamin K 3 affects the expression of LTV1 mRNA
CTD
PMID:20044591
NCBI chr 1:9,385,834...9,398,557
Ensembl chr 1:9,385,830...9,398,677
G
Lyar
Ly1 antibody reactive
affects expression
ISO
Vitamin K 3 affects the expression of LYAR mRNA
CTD
PMID:20044591
NCBI chr14:76,789,193...76,802,973
Ensembl chr14:76,789,200...76,802,765
G
Mab21l4
mab-21 like 4
affects expression
ISO
Vitamin K 3 affects the expression of MAB21L4 mRNA
CTD
PMID:20044591
NCBI chr 9:101,138,408...101,148,516
Ensembl chr 9:101,138,408...101,147,915
G
Maf
MAF bZIP transcription factor
affects expression
ISO
Vitamin K 3 affects the expression of MAF mRNA
CTD
PMID:20044591
NCBI chr19:60,259,200...60,622,145
Ensembl chr19:60,269,541...60,621,378
G
Maff
MAF bZIP transcription factor F
affects expression
ISO
Vitamin K 3 affects the expression of MAFF mRNA
CTD
PMID:20044591
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
G
Mafg
MAF bZIP transcription factor G
increases expression affects expression
ISO
Vitamin K 3 results in increased expression of MAFG mRNA Vitamin K 3 affects the expression of MAFG mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr10:106,401,633...106,410,159
G
Maged1
MAGE family member D1
affects expression
ISO
Vitamin K 3 affects the expression of MAGED1 mRNA
CTD
PMID:20044591
NCBI chr X:63,416,464...63,423,167
Ensembl chr X:63,416,466...63,423,112
G
Maob
monoamine oxidase B
multiple interactions decreases activity
ISO
Vitamin K 3 inhibits the reaction [MAOB protein results in increased oxidation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] Vitamin K 3 results in decreased activity of MAOB protein
CTD
PMID:21554916
NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions
ISO
[Metyrapone co-treated with Vitamin K 3] results in increased expression of MAP1LC3B protein; [S 3483 co-treated with Vitamin K 3] results in increased expression of MAP1LC3B protein
CTD
PMID:19819344
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
G
Map4
microtubule-associated protein 4
affects expression
ISO
Vitamin K 3 affects the expression of MAP4 mRNA
CTD
PMID:20044591
NCBI chr 8:118,800,393...118,942,805
Ensembl chr 8:118,804,022...118,942,805
G
Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
affects expression
ISO
Vitamin K 3 affects the expression of MAP4K4 mRNA
CTD
PMID:20044591
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
G
Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation increases activity
EXP ISO
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein] schizandrin B promotes the reaction [Vitamin K 3 results in increased activity of MAPK1 protein] [1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]
CTD
PMID:11880281 PMID:16310883 PMID:16507596 PMID:16996477 PMID:21250784
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk10
mitogen activated protein kinase 10
decreases activity multiple interactions
ISO EXP
Vitamin K 3 results in decreased activity of MAPK10 protein Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK10 protein
CTD
PMID:10531305 PMID:19386027
NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100
G
Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation increases activity
EXP ISO
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein] schizandrin B promotes the reaction [Vitamin K 3 results in increased activity of MAPK3 protein] [1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]
CTD
PMID:11880281 PMID:16310883 PMID:16507596 PMID:16996477 PMID:21250784
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions increases activity affects response to substance increases phosphorylation
EXP ISO
Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein Vitamin K 3 results in increased activity of MAPK8 protein MAPK8 protein affects the susceptibility to Vitamin K 3 Vitamin K 3 results in increased phosphorylation of MAPK8 protein
CTD
PMID:12215205 PMID:16310883 PMID:19386027
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
G
Mat2a
methionine adenosyltransferase 2A
affects expression
ISO
Vitamin K 3 affects the expression of MAT2A mRNA
CTD
PMID:20044591
NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645
G
Mbd2
methyl-CpG binding domain protein 2
affects expression
ISO
Vitamin K 3 affects the expression of MBD2 mRNA
CTD
PMID:20829426
NCBI chr18:66,449,196...66,516,112
Ensembl chr18:66,449,358...66,516,111
G
Mc1r
melanocortin 1 receptor
affects expression
ISO
Vitamin K 3 affects the expression of MC1R mRNA
CTD
PMID:20044591
NCBI chr19:68,360,950...68,363,877
Ensembl chr19:68,360,950...68,363,877
G
Mccc1
methylcrotonyl-CoA carboxylase subunit 1
affects expression
ISO
Vitamin K 3 affects the expression of MCCC1 mRNA
CTD
PMID:20044591
NCBI chr 2:120,727,313...120,779,334
Ensembl chr 2:120,727,316...120,779,554
G
Mcf2l
MCF.2 cell line derived transforming sequence-like
affects expression
ISO
Vitamin K 3 affects the expression of MCF2L mRNA
CTD
PMID:20044591
NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956
G
Mcm3
minichromosome maintenance complex component 3
affects expression
ISO
Vitamin K 3 affects the expression of MCM3 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746
G
Mcm5
minichromosome maintenance complex component 5
affects expression
ISO
Vitamin K 3 affects the expression of MCM5 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
G
Mcm6
minichromosome maintenance complex component 6
affects expression
ISO
Vitamin K 3 affects the expression of MCM6 mRNA
CTD
PMID:20044591
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
G
Mcmbp
minichromosome maintenance complex binding protein
affects expression
ISO
Vitamin K 3 affects the expression of MCMBP mRNA
CTD
PMID:20044591
NCBI chr 1:192,702,383...192,747,381
Ensembl chr 1:192,702,385...192,755,975
G
Mdc1
mediator of DNA damage checkpoint 1
affects expression
ISO
Vitamin K 3 affects the expression of MDC1 mRNA
CTD
PMID:20044591
NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
G
Mdm2
MDM2 proto-oncogene
multiple interactions decreases expression
ISO
EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein]
CTD
PMID:25005833
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
G
Me1
malic enzyme 1
increases expression
ISO
Vitamin K 3 results in increased expression of ME1 mRNA
CTD
PMID:12414654
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
G
Med9
mediator complex subunit 9
affects expression
ISO
Vitamin K 3 affects the expression of MED9 mRNA
CTD
PMID:20044591
NCBI chr10:45,250,229...45,264,988
Ensembl chr10:45,250,223...45,264,987
G
Met
MET proto-oncogene, receptor tyrosine kinase
increases expression
ISO
Vitamin K 3 results in increased expression of MET mRNA
CTD
PMID:25270620
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
G
Metap1
methionyl aminopeptidase 1
affects expression
ISO
Vitamin K 3 affects the expression of METAP1 mRNA
CTD
PMID:20044591
NCBI chr 2:229,664,677...229,697,730
Ensembl chr 2:229,664,677...229,719,084
G
Mex3d
mex-3 RNA binding family member D
affects expression
ISO
Vitamin K 3 affects the expression of MEX3D mRNA
CTD
PMID:20044591
NCBI chr 7:9,976,253...9,983,383
Ensembl chr 7:9,976,253...9,983,383
G
Mff
mitochondrial fission factor
affects expression
ISO
Vitamin K 3 affects the expression of MFF mRNA
CTD
PMID:20044591
NCBI chr 9:91,455,931...91,484,171
Ensembl chr 9:91,455,871...91,484,171
G
Mfge8
milk fat globule EGF and factor V/VIII domain containing
affects expression
ISO
Vitamin K 3 affects the expression of MFGE8 mRNA
CTD
PMID:20044591
NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431
G
Mfsd1
major facilitator superfamily domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of MFSD1 mRNA
CTD
PMID:20044591
NCBI chr 2:154,156,167...154,176,209
Ensembl chr 2:154,156,166...154,177,086
G
Mfsd5
major facilitator superfamily domain containing 5
affects expression
ISO
Vitamin K 3 affects the expression of SLC61A1 mRNA
CTD
PMID:20044591
NCBI chr 7:135,287,683...135,289,964
Ensembl chr 7:135,269,076...135,290,342
G
Mia2
MIA SH3 domain ER export factor 2
increases expression
ISO
Vitamin K 3 results in increased expression of MIA2 mRNA
CTD
PMID:12414654
NCBI chr 6:82,522,398...82,620,136
Ensembl chr 6:82,522,422...82,620,178
G
Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of MICAL2 mRNA
CTD
PMID:20044591
NCBI chr 1:175,780,441...175,965,157
Ensembl chr 1:175,825,596...175,905,155
G
Mindy1
MINDY lysine 48 deubiquitinase 1
affects expression
ISO
Vitamin K 3 affects the expression of MINDY1 mRNA
CTD
PMID:20044591
NCBI chr 2:185,550,026...185,561,987
Ensembl chr 2:185,548,993...185,561,986
G
Mitd1
microtubule interacting and trafficking domain containing 1
increases expression
ISO
Vitamin K 3 results in increased expression of MITD1 mRNA
CTD
PMID:25270620
NCBI chr 9:47,609,743...47,621,033
Ensembl chr 9:47,609,744...47,621,033
G
Mixl1
Mix paired-like homeobox 1
affects expression
ISO
Vitamin K 3 affects the expression of MIXL1 mRNA
CTD
PMID:23410634
NCBI chr13:94,953,907...94,957,938
Ensembl chr13:94,953,907...94,957,938
G
Mlxip
MLX interacting protein
affects expression
ISO
Vitamin K 3 affects the expression of MLXIP mRNA
CTD
PMID:20044591
NCBI chr12:38,789,404...38,853,059
Ensembl chr12:38,789,404...38,853,059
G
Mmd
monocyte to macrophage differentiation-associated
affects expression
ISO
Vitamin K 3 affects the expression of MMD mRNA
CTD
PMID:20044591
NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609
G
Mmp2
matrix metallopeptidase 2
decreases expression
ISO
Vitamin K 3 results in decreased expression of MMP2 protein
CTD
PMID:31238027
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
G
Mmp9
matrix metallopeptidase 9
decreases expression
ISO
Vitamin K 3 results in decreased expression of MMP9 protein
CTD
PMID:31238027
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Mnt
MAX network transcriptional repressor
affects expression
ISO
Vitamin K 3 affects the expression of MNT mRNA
CTD
PMID:20044591
NCBI chr10:60,197,654...60,213,221
Ensembl chr10:60,197,948...60,213,209
G
Mogs
mannosyl-oligosaccharide glucosidase
affects expression
ISO
Vitamin K 3 affects the expression of MOGS mRNA
CTD
PMID:20044591
NCBI chr 4:117,179,335...117,182,738
Ensembl chr 4:117,179,335...117,182,744
G
Morc4
MORC family CW-type zinc finger 4
affects expression
ISO
Vitamin K 3 affects the expression of MORC4 mRNA
CTD
PMID:20044591
NCBI chr X:108,269,197...108,317,611
Ensembl chr X:108,269,383...108,317,553
G
Mosmo
modulator of smoothened
affects expression
ISO
Vitamin K 3 affects the expression of MOSMO mRNA
CTD
PMID:20044591
NCBI chr 1:184,648,985...184,719,820
Ensembl chr 1:184,648,985...184,719,820
G
Mpc2
mitochondrial pyruvate carrier 2
affects expression
ISO
Vitamin K 3 affects the expression of MPC2 mRNA
CTD
PMID:20044591
NCBI chr13:80,261,143...80,280,668
Ensembl chr13:80,259,727...80,280,668
G
Mpnd
MPN domain containing
affects expression
ISO
Vitamin K 3 affects the expression of MPND mRNA
CTD
PMID:20044591
NCBI chr 9:926,714...933,620
Ensembl chr 9:925,799...933,616
G
Mrnip
MRN complex interacting protein
affects expression
ISO
Vitamin K 3 affects the expression of MRNIP mRNA
CTD
PMID:20044591
NCBI chr10:35,002,440...35,026,555
G
Mrpl33
mitochondrial ribosomal protein L33
affects expression
ISO
Vitamin K 3 affects the expression of MRPL33 mRNA
CTD
PMID:20044591
NCBI chr 6:30,545,794...30,553,987
Ensembl chr 6:30,545,794...30,553,987
G
Mrpl38
mitochondrial ribosomal protein L38
increases expression
ISO
Vitamin K 3 results in increased expression of MRPL38 mRNA
CTD
PMID:25270620
NCBI chr10:101,864,242...101,871,048
Ensembl chr10:101,863,318...101,871,048
G
Mrps12
mitochondrial ribosomal protein S12
affects expression
ISO
Vitamin K 3 affects the expression of MRPS12 mRNA
CTD
PMID:20044591
NCBI chr 1:93,153,424...93,156,422
Ensembl chr 1:93,153,425...93,159,629
G
Mrs2
magnesium transporter MRS2
affects expression
ISO
Vitamin K 3 affects the expression of MRS2 mRNA
CTD
PMID:20044591
NCBI chr17:40,491,963...40,515,116
Ensembl chr17:40,491,963...40,511,232
G
Msh2
mutS homolog 2
affects expression multiple interactions
ISO
Vitamin K 3 affects the expression of MSH2 mRNA MSH2 protein inhibits the reaction [POLK protein results in decreased susceptibility to Vitamin K 3]
CTD
PMID:20044591 PMID:31294882
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
G
Msh6
mutS homolog 6
affects expression
ISO
Vitamin K 3 affects the expression of MSH6 mRNA
CTD
PMID:20044591
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
G
Msmb
microseminoprotein, beta
affects expression
ISO
Vitamin K 3 affects the expression of MSMB mRNA
CTD
PMID:20044591
NCBI chr16:7,372,803...7,393,406
Ensembl chr16:7,372,819...7,393,405
G
Msrb2
methionine sulfoxide reductase B2
affects expression
ISO
Vitamin K 3 affects the expression of MSRB2 mRNA
CTD
PMID:20044591
NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391
G
Mt1-ps3
metallothionein 1, pseudogene 3
affects expression
ISO
Vitamin K 3 affects the expression of MT1E mRNA
CTD
PMID:20044591
NCBI chr17:79,695,812...79,696,200
Ensembl chr17:79,695,809...79,696,200
G
Mt1a
metallothionein 1A
increases expression
ISO
Vitamin K 3 results in increased expression of MT1 mRNA
CTD
PMID:25270620
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
G
Mt2
metallothionein 2
increases expression
ISO
Vitamin K 3 results in increased expression of MT2A mRNA
CTD
PMID:12414654
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
G
Mta2
metastasis associated 1 family, member 2
affects expression
ISO
Vitamin K 3 affects the expression of MTA2 mRNA
CTD
PMID:20044591
NCBI chr 1:215,267,286...215,276,008
Ensembl chr 1:215,267,046...215,276,062
G
Mtarc1
mitochondrial amidoxime reducing component 1
affects expression
ISO
Vitamin K 3 affects the expression of MTARC1 mRNA
CTD
PMID:23410634
NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252
G
Mthfd1
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
affects expression
ISO
Vitamin K 3 affects the expression of MTHFD1 mRNA
CTD
PMID:20044591
NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:100,713,681...100,781,957
G
Mxd1
max dimerization protein 1
affects expression
ISO
Vitamin K 3 affects the expression of MXD1 mRNA
CTD
PMID:20044591
NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129
G
Myadm
myeloid-associated differentiation marker
affects expression
ISO
Vitamin K 3 affects the expression of MYADM mRNA
CTD
PMID:20044591
NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
G
Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression affects expression
ISO
Vitamin K 3 results in decreased expression of MYC Vitamin K 3 affects the expression of MYC mRNA
CTD
PMID:10231603 PMID:20044591
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
G
Myl6
myosin light chain 6
affects expression
ISO
Vitamin K 3 affects the expression of MYL6 mRNA
CTD
PMID:20044591
NCBI chr 7:1,495,301...1,498,512
Ensembl chr 7:1,495,747...1,498,344
G
Mylk
myosin light chain kinase
affects expression
ISO
Vitamin K 3 affects the expression of MYLK mRNA
CTD
PMID:23410634
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
G
Myo10
myosin X
affects expression
ISO
Vitamin K 3 affects the expression of MYO10 mRNA
CTD
PMID:20044591
NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:77,831,532...78,036,137
G
Myo19
myosin XIX
affects expression
ISO
Vitamin K 3 affects the expression of MYO19 mRNA
CTD
PMID:20044591
NCBI chr10:70,250,500...70,279,867
Ensembl chr10:70,250,022...70,279,858
G
Myrf
myelin regulatory factor
affects expression
ISO
Vitamin K 3 affects the expression of MYRF mRNA
CTD
PMID:20044591
NCBI chr 1:216,279,057...216,311,155
Ensembl chr 1:216,279,057...216,311,178
G
N4bp3
Nedd4 binding protein 3
affects expression
ISO
Vitamin K 3 affects the expression of N4BP3 mRNA
CTD
PMID:20044591
NCBI chr10:36,400,053...36,407,609
Ensembl chr10:36,400,057...36,407,637
G
Nab1
Ngfi-A binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of NAB1 mRNA
CTD
PMID:20044591
NCBI chr 9:56,545,547...56,585,045
Ensembl chr 9:56,545,729...56,614,210
G
Nabp1
nucleic acid binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of NABP1 mRNA
CTD
PMID:20044591
NCBI chr 9:57,570,326...57,625,926
Ensembl chr 9:57,618,505...57,626,052
G
Nacc2
NACC family member 2
affects expression
ISO
Vitamin K 3 affects the expression of NACC2 mRNA
CTD
PMID:20044591
NCBI chr 3:29,278,077...29,345,098
Ensembl chr 3:29,281,190...29,344,840
G
Naglu
N-acetyl-alpha-glucosaminidase
affects expression
ISO
Vitamin K 3 affects the expression of NAGLU mRNA
CTD
PMID:20044591
NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,501,836...86,509,315
G
Ncapg
non-SMC condensin I complex, subunit G
affects expression
ISO
Vitamin K 3 affects the expression of NCAPG mRNA
CTD
PMID:20044591
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
G
Ncaph
non-SMC condensin I complex, subunit H
affects expression
ISO
Vitamin K 3 affects the expression of NCAPH mRNA
CTD
PMID:20044591
NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502
G
Ncf1
neutrophil cytosolic factor 1
increases expression
ISO
Vitamin K 3 results in increased expression of NCF1 mRNA; Vitamin K 3 results in increased expression of NCF1 protein
CTD
PMID:16507596 PMID:25270620
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
G
Ncf2
neutrophil cytosolic factor 2
increases expression
ISO
Vitamin K 3 results in increased expression of NCF2 protein
CTD
PMID:16507596
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
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Ncor2
nuclear receptor co-repressor 2
affects expression
ISO
Vitamin K 3 affects the expression of NCOR2 mRNA
CTD
PMID:20044591
NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612
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Ncs1
neuronal calcium sensor 1
affects expression
ISO
Vitamin K 3 affects the expression of FREQ mRNA
CTD
PMID:20044591
NCBI chr 3:34,920,949...34,966,554
Ensembl chr 3:34,920,971...34,968,711
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Ncstn
nicastrin
affects expression
ISO
Vitamin K 3 affects the expression of NCSTN mRNA
CTD
PMID:20044591
NCBI chr13:87,062,827...87,078,839
Ensembl chr13:87,062,831...87,078,839
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Ndc1
NDC1 transmembrane nucleoporin
affects expression
ISO
Vitamin K 3 affects the expression of NDC1 mRNA
CTD
PMID:20044591
NCBI chr 5:127,384,172...127,431,093
Ensembl chr 5:127,384,665...127,431,090
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Ndc80
NDC80 kinetochore complex component
affects expression
ISO
Vitamin K 3 affects the expression of NDC80 mRNA
CTD
PMID:23410634
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
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Nde1
nudE neurodevelopment protein 1
affects expression
ISO
Vitamin K 3 affects the expression of NDE1 mRNA
CTD
PMID:20044591
NCBI chr10:1,347,010...1,391,167
Ensembl chr10:1,347,018...1,383,447
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Ndrg1
N-myc downstream regulated 1
affects expression
ISO
Vitamin K 3 affects the expression of NDRG1 mRNA
CTD
PMID:20044591
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913
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Ndufb1
NADH:ubiquinone oxidoreductase subunit B1
affects expression
ISO
Vitamin K 3 affects the expression of NDUFB1 mRNA
CTD
PMID:20044591
NCBI chr 6:126,880,537...126,888,935
Ensembl chr 6:126,880,537...126,888,864
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Ndufs2
NADH:ubiquinone oxidoreductase core subunit S2
affects expression
ISO
Vitamin K 3 affects the expression of NDUFS2 mRNA
CTD
PMID:20044591
NCBI chr13:86,186,867...86,203,914
Ensembl chr13:86,186,870...86,203,608
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Necap1
NECAP endocytosis associated 1
affects expression
ISO
Vitamin K 3 affects the expression of NECAP1 mRNA
CTD
PMID:23410634
NCBI chr 4:157,775,890...157,790,992
Ensembl chr 4:157,775,896...157,790,984
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Neo1
neogenin 1
affects expression
ISO
Vitamin K 3 affects the expression of NEO1 mRNA
CTD
PMID:20044591
NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:68,169,716...68,322,152
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Net1
neuroepithelial cell transforming 1
affects expression
ISO
Vitamin K 3 affects the expression of NET1 mRNA
CTD
PMID:20044591
NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270
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Nf2
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
affects expression
ISO
Vitamin K 3 affects the expression of NF2 mRNA
CTD
PMID:20044591
NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions increases expression affects response to substance affects expression
ISO
[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3 Vitamin K 3 results in increased expression of NFE2L2 mRNA [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Vitamin K 3 Vitamin K 3 affects the expression of NFE2L2 mRNA NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Vitamin K 3]
CTD
PMID:19303893 PMID:19608619 PMID:20044591 PMID:20932822 PMID:23410634 PMID:26862668 More...
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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Nfe2l3
NFE2 like bZIP transcription factor 3
affects expression
ISO
Vitamin K 3 affects the expression of NFE2L3 mRNA
CTD
PMID:20044591
NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532
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Nfkb1
nuclear factor kappa B subunit 1
affects expression multiple interactions
ISO
Vitamin K 3 affects the expression of NFKB1 mRNA Vitamin K 3 inhibits the reaction [Nicotine results in increased activity of NFKB1 protein]
CTD
PMID:16598845 PMID:20044591
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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Nfkbia
NFKB inhibitor alpha
affects expression
ISO
Vitamin K 3 affects the expression of NFKBIA mRNA
CTD
PMID:23410634
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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Nfkbie
NFKB inhibitor epsilon
affects expression
ISO
Vitamin K 3 affects the expression of NFKBIE mRNA
CTD
PMID:20044591
NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872
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Nfs1
NFS1 cysteine desulfurase
affects expression
ISO
Vitamin K 3 affects the expression of NFS1 mRNA
CTD
PMID:20044591
NCBI chr 3:165,097,390...165,119,730
Ensembl chr 3:165,097,391...165,119,737
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Nif3l1
NGG1 interacting factor 3 like 1
affects expression
ISO
Vitamin K 3 affects the expression of NIF3L1 mRNA
CTD
PMID:20044591
NCBI chr 9:67,474,286...67,494,350
Ensembl chr 9:67,474,351...67,494,350
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Nkd1
NKD inhibitor of WNT signaling pathway 1
affects expression
ISO
Vitamin K 3 affects the expression of NKD1 mRNA
CTD
PMID:23410634
NCBI chr19:34,649,803...34,722,846
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Nmb
neuromedin B
affects expression
ISO
Vitamin K 3 affects the expression of NMB mRNA
CTD
PMID:20044591
NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
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Nmd3
NMD3 ribosome export adaptor
affects expression
ISO
Vitamin K 3 affects the expression of NMD3 mRNA
CTD
PMID:23410634
NCBI chr 2:156,285,773...156,348,394
Ensembl chr 2:156,322,963...156,350,903
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Noa1
nitric oxide associated 1
affects expression
ISO
Vitamin K 3 affects the expression of NOA1 mRNA
CTD
PMID:20044591
NCBI chr14:31,189,570...31,205,600
Ensembl chr14:31,188,978...31,205,599
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Nol7
nucleolar protein 7
affects expression
ISO
Vitamin K 3 affects the expression of NOL7 mRNA
CTD
PMID:20044591
NCBI chr17:21,509,605...21,512,879
Ensembl chr17:21,509,605...21,513,196
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Nolc1
nucleolar and coiled-body phosphoprotein 1
affects expression
ISO
Vitamin K 3 affects the expression of NOLC1 mRNA
CTD
PMID:20044591
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
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Nop16
NOP16 nucleolar protein
affects expression
ISO
Vitamin K 3 affects the expression of NOP16 mRNA
CTD
PMID:20044591
NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038
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Nop56
NOP56 ribonucleoprotein
affects expression
ISO
Vitamin K 3 affects the expression of NOP56 mRNA
CTD
PMID:20044591
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
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Nop58
NOP58 ribonucleoprotein
affects expression
ISO
Vitamin K 3 affects the expression of NOP58 mRNA
CTD
PMID:20044591
NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909
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Nos2
nitric oxide synthase 2
affects expression
ISO
Vitamin K 3 affects the expression of NOS2A mRNA
CTD
PMID:20044591
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Nos3
nitric oxide synthase 3
decreases activity
EXP
Vitamin K 3 results in decreased activity of NOS3 protein
CTD
PMID:11551532
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
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Nostrin
nitric oxide synthase trafficking
affects expression
ISO
Vitamin K 3 affects the expression of NOSTRIN mRNA
CTD
PMID:20044591
NCBI chr 3:74,312,594...74,378,852
Ensembl chr 3:74,312,647...74,396,455
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Nox1
NADPH oxidase 1
increases expression
ISO
Vitamin K 3 results in increased expression of NOX1 mRNA; Vitamin K 3 results in increased expression of NOX1 protein
CTD
PMID:16507596
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
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Nox4
NADPH oxidase 4
increases expression
ISO
Vitamin K 3 results in increased expression of NOX4 mRNA; Vitamin K 3 results in increased expression of NOX4 protein
CTD
PMID:16507596
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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Npepps
aminopeptidase puromycin sensitive
affects expression
ISO
Vitamin K 3 affects the expression of NPEPPS mRNA
CTD
PMID:20044591
NCBI chr10:82,687,869...82,770,363
Ensembl chr10:82,687,871...82,770,363
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Nprl3
NPR3-like, GATOR1 complex subunit
affects expression
ISO
Vitamin K 3 affects the expression of NPRL3 mRNA
CTD
PMID:20044591
NCBI chr10:15,859,739...15,900,261
Ensembl chr10:15,859,789...15,902,332
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions increases response to substance
ISO EXP
Vitamin K 3 results in increased expression of NQO1 mRNA NQO1 gene mutant form promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide] Dicumarol inhibits the reaction [NQO1 protein inhibits the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]]; NAD promotes the reaction [NQO1 protein results in increased reduction of Vitamin K 3]; NADP promotes the reaction [NQO1 protein results in increased reduction of Vitamin K 3]; NQO1 protein inhibits the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide] NQO1 gene mutant form results in increased susceptibility to Vitamin K 3
CTD
PMID:12414654 PMID:21859103 PMID:22846377 PMID:25270620 PMID:27558805
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
increases activity increases reduction decreases response to substance affects response to substance multiple interactions
ISO
NQO2 protein results in increased activity of Vitamin K 3 NQO2 protein results in increased reduction of Vitamin K 3 NQO2 gene mutant form results in decreased susceptibility to Vitamin K 3 NQO2 affects the susceptibility to Vitamin K 3 [NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3; [NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3; Amodiaquine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Clozapine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Mefenamic Acid inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]
CTD
PMID:12351651 PMID:17762829 PMID:20399199 PMID:21859103 PMID:29281794
NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662
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Nr0b2
nuclear receptor subfamily 0, group B, member 2
affects expression
ISO
Vitamin K 3 affects the expression of NR0B2 mRNA
CTD
PMID:23410634
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
affects expression
ISO
Vitamin K 3 affects the expression of NR1H4 mRNA
CTD
PMID:23410634
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
affects expression
ISO
Vitamin K 3 affects the expression of NR2F2 mRNA
CTD
PMID:20044591
NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:133,420,227...133,431,975
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
ISO
Vitamin K 3 affects the expression of NR3C1 mRNA
CTD
PMID:23410634
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
affects expression increases expression
ISO
Vitamin K 3 affects the expression of NR4A1 mRNA Vitamin K 3 results in increased expression of NR4A1 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
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Nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
affects expression
ISO
Vitamin K 3 affects the expression of NSMCE4A mRNA
CTD
PMID:20044591
NCBI chr 1:194,532,364...194,539,456
Ensembl chr 1:194,525,648...194,539,456
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Nsun2
NOP2/Sun RNA methyltransferase 2
affects expression
ISO
Vitamin K 3 affects the expression of NSUN2 mRNA
CTD
PMID:20044591
NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:35,490,583...35,514,306
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Ntf3
neurotrophin 3
affects expression
ISO
Vitamin K 3 affects the expression of NTF3 mRNA
CTD
PMID:20044591
NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349
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Ntrk1
neurotrophic receptor tyrosine kinase 1
increases phosphorylation
ISO
Vitamin K 3 analog results in increased phosphorylation of NTRK1 protein
CTD
PMID:19273458
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
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Nudcd2
NudC domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of NUDCD2 mRNA
CTD
PMID:20044591
NCBI chr10:25,665,493...25,671,010
Ensembl chr10:25,665,509...25,682,902
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Nudt22
nudix hydrolase 22
affects expression
ISO
Vitamin K 3 affects the expression of NUDT22 mRNA
CTD
PMID:20044591
NCBI chr 1:213,612,008...213,615,626
Ensembl chr 1:213,612,009...213,615,713
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Nudt6
nudix hydrolase 6
affects expression
ISO
Vitamin K 3 affects the expression of NUDT6 mRNA
CTD
PMID:23410634
NCBI chr 2:122,218,031...122,234,488
Ensembl chr 2:122,217,861...122,234,344
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Numb
NUMB, endocytic adaptor protein
decreases expression
ISO
Vitamin K 3 results in decreased expression of NUMB protein
CTD
PMID:25005833
NCBI chr 6:109,162,499...109,284,527
Ensembl chr 6:109,162,499...109,284,463
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Nup107
nucleoporin 107
affects expression
ISO
Vitamin K 3 affects the expression of NUP107 mRNA
CTD
PMID:20044591
NCBI chr 7:55,239,610...55,285,050
Ensembl chr 7:55,239,613...55,285,234
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Nup160
nucleoporin 160
affects expression
ISO
Vitamin K 3 affects the expression of NUP160 mRNA
CTD
PMID:20044591
NCBI chr 3:97,120,723...97,183,227
Ensembl chr 3:97,121,628...97,180,720
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Oat
ornithine aminotransferase
affects expression
ISO
Vitamin K 3 affects the expression of OAT mRNA
CTD
PMID:20044591
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
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Oaz1
ornithine decarboxylase antizyme 1
affects expression
ISO
Vitamin K 3 affects the expression of OAZ1 mRNA
CTD
PMID:20044591
NCBI chr 7:9,534,530...9,536,990
Ensembl chr 7:9,533,811...9,536,990
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Ocel1
occludin/ELL domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of OCEL1 mRNA
CTD
PMID:20044591
NCBI chr16:18,076,428...18,079,068
Ensembl chr16:18,077,266...18,079,374
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Odc1
ornithine decarboxylase 1
affects expression
ISO
Vitamin K 3 affects the expression of ODC1 mRNA
CTD
PMID:20044591
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
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Ogdhl
oxoglutarate dehydrogenase L
affects expression
ISO
Vitamin K 3 affects the expression of OGDHL mRNA
CTD
PMID:20044591
NCBI chr16:7,584,666...7,610,705
Ensembl chr16:7,584,657...7,610,698
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Ogfod3
2-oxoglutarate and iron-dependent oxygenase domain containing 3
affects expression
ISO
Vitamin K 3 affects the expression of OGFOD3 mRNA
CTD
PMID:20044591
NCBI chr10:106,950,640...106,978,422
Ensembl chr10:106,950,641...106,978,992
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Ogg1
8-oxoguanine DNA glycosylase
increases response to substance increases expression
ISO
OGG1 protein SNP results in increased susceptibility to Vitamin K 3 Vitamin K 3 results in increased expression of OGG1 mRNA
CTD
PMID:17651912 PMID:23410634
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
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Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase
affects expression
ISO
Vitamin K 3 affects the expression of OGT mRNA
CTD
PMID:20044591
NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123
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Ormdl2
ORMDL sphingolipid biosynthesis regulator 2
affects expression
ISO
Vitamin K 3 affects the expression of ORMDL2 mRNA
CTD
PMID:20044591
NCBI chr 7:1,832,368...1,835,501
Ensembl chr 7:1,832,368...1,836,223
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Oser1
oxidative stress responsive serine-rich 1
affects expression
ISO
Vitamin K 3 affects the expression of OSER1 mRNA
CTD
PMID:20044591
NCBI chr 3:172,486,417...172,504,607
Ensembl chr 3:172,486,440...172,504,597
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Osgin1
oxidative stress induced growth inhibitor 1
increases expression affects expression
ISO
Vitamin K 3 results in increased expression of OSGIN1 mRNA Vitamin K 3 affects the expression of OSGIN1 mRNA
CTD
PMID:12414654 PMID:23410634
NCBI chr19:64,380,336...64,409,165
Ensembl chr19:64,401,173...64,409,162
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Ovol1
ovo like transcriptional repressor 1
affects expression
ISO
Vitamin K 3 affects the expression of OVOL1 mRNA
CTD
PMID:20044591
NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:212,284,605...212,296,106
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Pabpc1
poly(A) binding protein, cytoplasmic 1
affects expression
ISO
Vitamin K 3 affects the expression of PABPC1 mRNA
CTD
PMID:20044591
NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050
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Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
ISO
Vitamin K 3 affects the expression of PAICS mRNA
CTD
PMID:20044591
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
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Palld
palladin, cytoskeletal associated protein
affects expression
ISO
Vitamin K 3 affects the expression of PALLD mRNA
CTD
PMID:23410634
NCBI chr16:33,238,943...33,632,236
Ensembl chr16:33,238,956...33,632,232
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Pam
peptidylglycine alpha-amidating monooxygenase
affects expression
ISO
Vitamin K 3 affects the expression of PAM mRNA
CTD
PMID:20044591
NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:105,445,929...105,719,285
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Panx1
Pannexin 1
increases expression
ISO
Vitamin K 3 results in increased expression of PANX1 mRNA
CTD
PMID:25270620
NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:20,132,165...20,171,200
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Parg
poly (ADP-ribose) glycohydrolase
multiple interactions affects response to substance
ISO
benzamide inhibits the reaction [PARG affects the susceptibility to Vitamin K 3]
CTD
PMID:15591342
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions affects response to substance
ISO
[sodium arsenite co-treated with Vitamin K 3] results in increased cleavage of PARP1 protein PARP1 protein affects the susceptibility to Vitamin K 3
CTD
PMID:19082730 PMID:21124846
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pawr
pro-apoptotic WT1 regulator
affects expression
ISO
Vitamin K 3 affects the expression of PAWR mRNA
CTD
PMID:23410634
NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492
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Paxip1
PAX interacting protein 1
affects expression
ISO
Vitamin K 3 affects the expression of PAXIP1 mRNA
CTD
PMID:20044591
NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488
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Pcbp1
poly(rC) binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of PCBP1 mRNA
CTD
PMID:20044591
NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111
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Pcca
propionyl-CoA carboxylase subunit alpha
affects expression
ISO
Vitamin K 3 affects the expression of PCCA mRNA
CTD
PMID:20044591
NCBI chr15:106,034,586...106,374,908
Ensembl chr15:106,034,610...106,374,908
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Pck1
phosphoenolpyruvate carboxykinase 1
affects expression
ISO
Vitamin K 3 affects the expression of PCK1 mRNA
CTD
PMID:20044591
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
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Pclaf
PCNA clamp associated factor
affects expression
ISO
Vitamin K 3 affects the expression of PCLAF mRNA
CTD
PMID:20044591
NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106
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Pcna
proliferating cell nuclear antigen
increases expression affects expression decreases expression multiple interactions
ISO
Vitamin K 3 results in increased expression of PCNA protein Vitamin K 3 affects the expression of PCNA mRNA Vitamin K 3 results in decreased expression of PCNA protein Alpha-Amanitin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]; Cycloheximide inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]; Dactinomycin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]
CTD
PMID:20044591 PMID:20829426 PMID:21533478
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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Pcyox1l
prenylcysteine oxidase 1 like
affects expression
ISO
Vitamin K 3 affects the expression of PCYOX1L mRNA
CTD
PMID:20044591
NCBI chr18:57,420,971...57,431,632
Ensembl chr18:57,420,977...57,431,632
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Pdcd4
programmed cell death 4
affects expression
ISO
Vitamin K 3 affects the expression of PDCD4 mRNA
CTD
PMID:20044591
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
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Pdia5
protein disulfide isomerase family A, member 5
affects expression
ISO
Vitamin K 3 affects the expression of PDIA5 mRNA
CTD
PMID:20044591
NCBI chr11:78,777,436...78,892,370
Ensembl chr11:78,777,419...78,864,329
G
Pdpn
podoplanin
increases expression
ISO
Vitamin K 3 results in increased expression of PDPN mRNA
CTD
PMID:19675304
NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637
G
Pdrg1
p53 and DNA damage regulated 1
affects expression
ISO
Vitamin K 3 affects the expression of PDRG1 mRNA
CTD
PMID:20044591
NCBI chr 3:161,937,812...161,943,981
Ensembl chr 3:161,937,815...161,948,995
G
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of PDXDC1 mRNA
CTD
PMID:20044591
NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,532,485...2,620,669
G
Pdzk1
PDZ domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of PDZK1 mRNA
CTD
PMID:20044591
NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806
G
Pepd
peptidase D
affects expression
ISO
Vitamin K 3 affects the expression of PEPD mRNA
CTD
PMID:20044591
NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190
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Per2
period circadian regulator 2
affects expression
ISO
Vitamin K 3 affects the expression of PER2 mRNA
CTD
PMID:20044591
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
G
Perp
p53 apoptosis effector related to PMP22
increases expression
ISO
Vitamin K 3 results in increased expression of PERP mRNA
CTD
PMID:21382384
NCBI chr 1:15,361,784...15,374,230
Ensembl chr 1:15,361,778...15,374,687
G
Pfkp
phosphofructokinase, platelet
decreases expression
ISO
Vitamin K 3 results in decreased expression of PFKP mRNA
CTD
PMID:25270620
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
G
Pgap6
post-GPI attachment to proteins 6
affects expression
ISO
Vitamin K 3 affects the expression of PGAP6 mRNA
CTD
PMID:20044591
NCBI chr10:15,643,081...15,652,912
Ensembl chr10:15,643,106...15,652,912
G
Pgd
phosphogluconate dehydrogenase
increases expression
ISO
Vitamin K 3 results in increased expression of PGD mRNA
CTD
PMID:25270620
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
G
Pggt1b
protein geranylgeranyltransferase type I subunit beta
increases expression
ISO
Vitamin K 3 results in increased expression of PGGT1B mRNA
CTD
PMID:12414654
NCBI chr18:41,138,536...41,182,145
Ensembl chr18:41,139,965...41,182,139
G
Pgk1
phosphoglycerate kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of PGK1 mRNA
CTD
PMID:20044591
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
G
Pgrmc1
progesterone receptor membrane component 1
increases expression
ISO
Vitamin K 3 results in increased expression of PGRMC1 mRNA
CTD
PMID:25270620
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
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Phb1
prohibitin 1
affects expression
ISO
Vitamin K 3 affects the expression of PHB1 mRNA
CTD
PMID:20044591
NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233
G
Phf10
PHD finger protein 10
affects expression
ISO
Vitamin K 3 affects the expression of PHF10 mRNA
CTD
PMID:20044591
NCBI chr 1:64,625,373...64,642,110
Ensembl chr 1:64,624,465...64,642,049
G
Phf21a
PHD finger protein 21A
decreases expression
ISO
Vitamin K 3 results in decreased expression of PHF21A mRNA
CTD
PMID:25270620
NCBI chr 3:98,600,933...98,791,132
Ensembl chr 3:98,613,844...98,787,350
G
Phlda1
pleckstrin homology-like domain, family A, member 1
affects expression
ISO
Vitamin K 3 affects the expression of PHLDA1 mRNA
CTD
PMID:20044591
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
G
Phlda2
pleckstrin homology-like domain, family A, member 2
affects expression
ISO
Vitamin K 3 affects the expression of PHLDA2 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920
G
Pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
affects expression
ISO
Vitamin K 3 affects the expression of PIK3C2B mRNA
CTD
PMID:20044591
NCBI chr13:47,046,866...47,107,733
Ensembl chr13:47,047,127...47,107,725
G
Pimreg
PICALM interacting mitotic regulator
affects expression
ISO
Vitamin K 3 affects the expression of PIMREG mRNA
CTD
PMID:20044591
NCBI chr10:57,168,136...57,173,713
Ensembl chr10:57,167,797...57,173,063
G
Pitx2
paired-like homeodomain 2
affects expression
ISO
Vitamin K 3 affects the expression of PITX2 mRNA
CTD
PMID:20044591
NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591
G
Pla2g12b
phospholipase A2, group XIIB
affects expression
ISO
Vitamin K 3 affects the expression of PLA2G12B mRNA
CTD
PMID:20044591
NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,913,259...27,932,148
G
Pla2g7
phospholipase A2 group VII
increases expression
ISO
Vitamin K 3 results in increased expression of PLA2G7 mRNA
CTD
PMID:25270620
NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747
G
Pla2r1
phospholipase A2 receptor 1
increases expression
ISO
Vitamin K 3 results in increased expression of PLA2R1 mRNA
CTD
PMID:12414654
NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:65,292,629...65,422,335
G
Plagl2
PLAG1 like zinc finger 2
affects expression
ISO
Vitamin K 3 affects the expression of PLAGL2 mRNA
CTD
PMID:20044591
NCBI chr 3:162,155,554...162,168,748
Ensembl chr 3:162,155,554...162,168,748
G
Plbd1
phospholipase B domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of PLBD1 mRNA
CTD
PMID:20044591
NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488
G
Plce1
phospholipase C, epsilon 1
affects expression
ISO
Vitamin K 3 affects the expression of PLCE1 mRNA
CTD
PMID:20044591
NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828
G
Pld3
phospholipase D family, member 3
affects expression
ISO
Vitamin K 3 affects the expression of PLD3 mRNA
CTD
PMID:20044591
NCBI chr 1:91,949,465...91,971,834
Ensembl chr 1:91,949,467...91,961,207
G
Plekha1
pleckstrin homology domain containing A1
affects expression
ISO
Vitamin K 3 affects the expression of PLEKHA1 mRNA
CTD
PMID:20044591
NCBI chr 1:194,858,239...194,909,418
Ensembl chr 1:194,851,547...194,909,413
G
Plekha6
pleckstrin homology domain containing A6
affects expression
ISO
Vitamin K 3 affects the expression of PLEKHA6 mRNA
CTD
PMID:20044591
NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003
G
Plekho1
pleckstrin homology domain containing O1
affects expression
ISO
Vitamin K 3 affects the expression of PLEKHO1 mRNA
CTD
PMID:23410634
NCBI chr 2:186,233,435...186,242,114
Ensembl chr 2:186,233,452...186,241,354
G
Plekho2
pleckstrin homology domain containing O2
affects expression
ISO
Vitamin K 3 affects the expression of PLEKHO2 mRNA
CTD
PMID:20044591
NCBI chr 8:74,973,578...75,000,532
Ensembl chr 8:74,974,740...75,000,430
G
Plk1
polo-like kinase 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of PLK1 mRNA
CTD
PMID:12414654
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
G
Plk3
polo-like kinase 3
affects expression
ISO
Vitamin K 3 affects the expression of PLK3 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900
G
Plpp1
phospholipid phosphatase 1
affects expression
ISO
Vitamin K 3 affects the expression of PLPP1 mRNA
CTD
PMID:20044591
NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
affects expression
ISO
Vitamin K 3 affects the expression of PMAIP1 mRNA
CTD
PMID:23410634
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
G
Pmepa1
prostate transmembrane protein, androgen induced 1
affects expression
ISO
Vitamin K 3 affects the expression of PMEPA1 mRNA
CTD
PMID:20044591
NCBI chr 3:182,430,193...182,478,649
Ensembl chr 3:182,430,193...182,478,649
G
Pmpcb
peptidase, mitochondrial processing subunit beta
affects expression
ISO
Vitamin K 3 affects the expression of PMPCB mRNA
CTD
PMID:20044591
NCBI chr 4:14,189,807...14,202,584
Ensembl chr 4:14,165,844...14,202,615
G
Pnn
pinin, desmosome associated protein
affects expression
ISO
Vitamin K 3 affects the expression of PNN mRNA
CTD
PMID:20044591
NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933
G
Pnp
purine nucleoside phosphorylase
affects expression
ISO
Vitamin K 3 affects the expression of PNP mRNA
CTD
PMID:20044591
NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162
G
Pnpt1
polyribonucleotide nucleotidyltransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of PNPT1 mRNA
CTD
PMID:20044591
NCBI chr14:107,078,486...107,109,628
Ensembl chr14:107,078,469...107,109,628
G
Podxl
podocalyxin-like
affects expression
ISO
Vitamin K 3 affects the expression of PODXL mRNA
CTD
PMID:20044591
NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
G
Pold4
DNA polymerase delta 4, accessory subunit
affects expression
ISO
Vitamin K 3 affects the expression of POLD4 mRNA
CTD
PMID:23410634
NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860
G
Pole2
DNA polymerase epsilon 2, accessory subunit
decreases expression
ISO
Vitamin K 3 results in decreased expression of POLE2 mRNA
CTD
PMID:12414654
NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361
G
Polk
DNA polymerase kappa
multiple interactions
ISO
MSH2 protein inhibits the reaction [POLK protein results in decreased susceptibility to Vitamin K 3]
CTD
PMID:31294882
NCBI chr 2:29,556,831...29,616,960
Ensembl chr 2:29,557,336...29,616,960
G
Polr1c
RNA polymerase I and III subunit C
affects expression
ISO
Vitamin K 3 affects the expression of POLR1C mRNA
CTD
PMID:20044591
NCBI chr 9:22,233,318...22,237,430
Ensembl chr 9:22,233,305...22,237,428
G
Polr3e
RNA polymerase III subunit E
affects expression
ISO
Vitamin K 3 affects the expression of POLR3E mRNA
CTD
PMID:20044591
NCBI chr 1:184,897,383...184,925,547
Ensembl chr 1:184,897,426...184,926,534
G
Pon3
paraoxonase 3
affects expression
ISO
Vitamin K 3 affects the expression of PON3 mRNA
CTD
PMID:20044591
NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244
G
Pop7
POP7 homolog, ribonuclease P/MRP subunit
affects expression
ISO
Vitamin K 3 affects the expression of POP7 mRNA
CTD
PMID:20044591
NCBI chr12:24,826,161...24,827,202
Ensembl chr12:24,809,994...24,827,522
G
Por
cytochrome p450 oxidoreductase
increases expression multiple interactions
ISO EXP
Vitamin K 3 results in increased expression of POR mRNA NADP promotes the reaction [POR protein results in increased reduction of Vitamin K 3]; POR protein promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]
CTD
PMID:27558805
NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
G
Ppargc1b
PPARG coactivator 1 beta
affects expression
ISO
Vitamin K 3 affects the expression of PPARGC1B mRNA
CTD
PMID:20044591
NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466
G
Ppcs
phosphopantothenoylcysteine synthetase
affects expression
ISO
Vitamin K 3 affects the expression of PPCS mRNA
CTD
PMID:20044591
NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
ISO
Vitamin K 3 affects the expression of PPDPF mRNA
CTD
PMID:20044591
NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599
G
Ppic
peptidylprolyl isomerase C
affects expression
ISO
Vitamin K 3 affects the expression of PPIC mRNA
CTD
PMID:20044591
NCBI chr18:49,040,690...49,053,296
Ensembl chr18:49,040,692...49,053,466
G
Ppif
peptidylprolyl isomerase F
affects expression
ISO
Vitamin K 3 affects the expression of PPIF mRNA
CTD
PMID:20044591
NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954
G
Ppil1
peptidylprolyl isomerase like 1
affects expression
ISO
Vitamin K 3 affects the expression of PPIL1 mRNA
CTD
PMID:20044591
NCBI chr20:7,303,919...7,323,962
Ensembl chr20:7,303,922...7,318,781
G
Ppm1d
protein phosphatase, Mg2+/Mn2+ dependent, 1D
increases expression
ISO
Vitamin K 3 results in increased expression of PPM1D mRNA
CTD
PMID:12414654
NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256
G
Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
affects expression
ISO
Vitamin K 3 affects the expression of PPP1R15A mRNA
CTD
PMID:20044591
NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774
G
Ppp1r16a
protein phosphatase 1, regulatory subunit 16A
affects expression
ISO
Vitamin K 3 affects the expression of PPP1R16A mRNA
CTD
PMID:20044591
NCBI chr 7:110,272,307...110,295,452
Ensembl chr 7:110,272,282...110,295,450
G
Ppp1r26
protein phosphatase 1, regulatory subunit 26
affects expression
ISO
Vitamin K 3 affects the expression of PPP1R26 mRNA
CTD
PMID:20044591
NCBI chr 3:32,179,686...32,188,069
Ensembl chr 3:32,177,235...32,188,264
G
Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
affects expression
ISO
Vitamin K 3 affects the expression of PPP1R3C mRNA
CTD
PMID:23410634
NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835
G
Ppp1r9a
protein phosphatase 1, regulatory subunit 9A
affects expression
ISO
Vitamin K 3 affects the expression of PPP1R9A mRNA
CTD
PMID:20044591
NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927
G
Ppp2cb
protein phosphatase 2 catalytic subunit beta
increases expression
ISO
Vitamin K 3 results in increased expression of PPP2CB mRNA
CTD
PMID:12414654
NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634
G
Ppp3cc
protein phosphatase 3 catalytic subunit gamma
affects expression
ISO
Vitamin K 3 affects the expression of PPP3CC mRNA
CTD
PMID:23410634
NCBI chr15:51,699,586...51,771,763
Ensembl chr15:51,700,255...51,771,538
G
Pprc1
PPARG related coactivator 1
affects expression
ISO
Vitamin K 3 affects the expression of PPRC1 mRNA
CTD
PMID:20044591
NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:254,851,164...254,867,570
G
Prdx1
peroxiredoxin 1
increases expression
ISO
Vitamin K 3 results in increased expression of PRDX1 mRNA
CTD
PMID:9506838
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
G
Prep
prolyl endopeptidase
affects expression
ISO
Vitamin K 3 affects the expression of PREP mRNA
CTD
PMID:20044591
NCBI chr20:50,138,588...50,235,549
Ensembl chr20:50,131,819...50,252,697
G
Prkab2
protein kinase AMP-activated non-catalytic subunit beta 2
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of PRKAB2 mRNA Vitamin K 3 results in decreased expression of PRKAB2 mRNA
CTD
PMID:20044591 PMID:25270620
NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608
G
Prkg1
protein kinase cGMP-dependent 1
increases oxidation multiple interactions
EXP
Vitamin K 3 results in increased oxidation of PRKG1 protein Resveratrol promotes the reaction [Vitamin K 3 results in increased oxidation of PRKG1 protein]
CTD
PMID:31116951
NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005
G
Prmt8
protein arginine methyltransferase 8
decreases expression
ISO
Vitamin K 3 results in decreased expression of PRMT8 mRNA
CTD
PMID:25270620
NCBI chr 4:162,221,986...162,304,036
Ensembl chr 4:162,221,986...162,307,310
G
Prss22
serine protease 22
affects expression
ISO
Vitamin K 3 affects the expression of PRSS22 mRNA
CTD
PMID:20044591
NCBI chr10:13,533,725...13,538,435
Ensembl chr10:13,533,725...13,538,435
G
Psat1
phosphoserine aminotransferase 1
affects expression
ISO
Vitamin K 3 affects the expression of PSAT1 mRNA
CTD
PMID:20044591
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
G
Psma6
proteasome 20S subunit alpha 6
affects expression
ISO
Vitamin K 3 affects the expression of PSMA6 mRNA
CTD
PMID:20044591
NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717
G
Psmb3
proteasome 20S subunit beta 3
affects expression
ISO
Vitamin K 3 affects the expression of PSMB3 mRNA
CTD
PMID:20044591
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
G
Psmd12
proteasome 26S subunit, non-ATPase 12
increases expression
ISO
Vitamin K 3 results in increased expression of PSMD12 mRNA
CTD
PMID:12414654
NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964
G
Psmg1
proteasome assembly chaperone 1
affects expression
ISO
Vitamin K 3 affects the expression of PSMG1 mRNA
CTD
PMID:20044591
NCBI chr11:48,745,581...48,755,040
Ensembl chr11:48,745,581...48,755,040
G
Psph
phosphoserine phosphatase
affects expression
ISO
Vitamin K 3 affects the expression of PSPH mRNA
CTD
PMID:20044591
NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180
G
Ptcd3
Pentatricopeptide repeat domain 3
affects expression
ISO
Vitamin K 3 affects the expression of PTCD3 mRNA
CTD
PMID:20044591
NCBI chr 4:105,480,699...105,508,007
Ensembl chr 4:105,480,709...105,513,276
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
Vitamin K 3 results in increased expression of PTGR1 mRNA
CTD
PMID:23410634 PMID:25270620
NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
G
Ptpn11
protein tyrosine phosphatase, non-receptor type 11
affects expression
ISO
Vitamin K 3 affects the expression of PTPN11 mRNA
CTD
PMID:20044591
NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577
G
Ptpra
protein tyrosine phosphatase, receptor type, A
affects expression
ISO
Vitamin K 3 affects the expression of PTPRA mRNA
CTD
PMID:20044591
NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:138,098,110...138,213,126
G
Ptprm
protein tyrosine phosphatase, receptor type, M
affects expression
ISO
Vitamin K 3 affects the expression of PTPRM mRNA
CTD
PMID:20044591
NCBI chr 9:114,086,380...114,791,000
Ensembl chr 9:114,086,380...114,790,477
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Ptrh1
peptidyl-tRNA hydrolase 1 homolog
affects expression
ISO
Vitamin K 3 affects the expression of PTRH1 mRNA
CTD
PMID:20044591
NCBI chr 3:36,462,575...36,475,605
Ensembl chr 3:36,462,575...36,476,139
G
Pudp
pseudouridine 5'-phosphatase
affects expression
ISO
Vitamin K 3 affects the expression of PUDP mRNA
CTD
PMID:20044591
NCBI chr18:46,064,867...46,067,247
Ensembl chr18:46,063,292...46,067,443
G
Puf60
poly-U binding splicing factor 60
affects expression
ISO
Vitamin K 3 affects the expression of PUF60 mRNA
CTD
PMID:20044591
NCBI chr 7:109,663,490...109,674,443
Ensembl chr 7:109,663,490...109,674,724
G
Pum3
pumilio RNA-binding family member 3
affects expression
ISO
Vitamin K 3 affects the expression of PUM3 mRNA
CTD
PMID:20044591
NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:234,487,954...234,527,612
G
Pura
purine rich element binding protein A
decreases expression
ISO
Vitamin K 3 results in decreased expression of PURA mRNA
CTD
PMID:25270620
NCBI chr18:28,159,103...28,179,539
Ensembl chr18:28,125,126...28,211,111
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Pus7
pseudouridine synthase 7
affects expression
ISO
Vitamin K 3 affects the expression of PUS7 mRNA
CTD
PMID:20044591
NCBI chr 4:12,252,553...12,293,547
Ensembl chr 4:12,252,545...12,293,539
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Pxmp4
peroxisomal membrane protein 4
affects expression
ISO
Vitamin K 3 affects the expression of PXMP4 mRNA
CTD
PMID:20044591
NCBI chr 3:163,553,582...163,570,829
Ensembl chr 3:163,553,599...163,570,829
G
Pxylp1
2-phosphoxylose phosphatase 1
affects expression
ISO
Vitamin K 3 affects the expression of PXYLP1 mRNA
CTD
PMID:20044591
NCBI chr 8:106,299,303...106,364,603
Ensembl chr 8:106,299,304...106,364,603
G
R3hdm2
R3H domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of R3HDM2 mRNA
CTD
PMID:20044591
NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862
G
Rab11fip1
RAB11 family interacting protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RAB11FIP1 mRNA
CTD
PMID:20044591
NCBI chr16:71,589,753...71,620,341
Ensembl chr16:71,589,753...71,620,341
G
Rab11fip4
RAB11 family interacting protein 4
affects expression
ISO
Vitamin K 3 affects the expression of RAB11FIP4 mRNA
CTD
PMID:20044591
NCBI chr10:65,048,070...65,156,086
Ensembl chr10:65,048,140...65,152,722
G
Rab3gap1
RAB3 GTPase activating protein catalytic subunit 1
affects expression
ISO
Vitamin K 3 affects the expression of RAB3GAP1 mRNA
CTD
PMID:20044591
NCBI chr13:41,908,179...41,981,611
Ensembl chr13:41,908,051...41,981,611
G
Rab5c
RAB5C, member RAS oncogene family
affects expression
ISO
Vitamin K 3 affects the expression of RAB5C mRNA
CTD
PMID:20044591
NCBI chr10:86,142,872...86,166,449
Ensembl chr10:86,142,873...86,166,449
G
Rack1
receptor for activated C kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of RACK1 mRNA
CTD
PMID:20044591
NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948
G
Rad23b
RAD23 homolog B, nucleotide excision repair protein
affects expression
ISO
Vitamin K 3 affects the expression of RAD23B mRNA
CTD
PMID:20044591
NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426
G
Rad51
RAD51 recombinase
affects expression
ISO
Vitamin K 3 affects the expression of RAD51 mRNA
CTD
PMID:20044591
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
G
Rai1
retinoic acid induced 1
affects expression
ISO
Vitamin K 3 affects the expression of RAI1 mRNA
CTD
PMID:20044591
NCBI chr10:45,412,748...45,507,747
Ensembl chr10:45,447,427...45,507,747
G
Ralgdsl1
ral guanine nucleotide dissociation stimulator like 1
affects expression
ISO
Vitamin K 3 affects the expression of RGL1 mRNA
CTD
PMID:20044591
NCBI chr13:67,184,402...67,454,019
Ensembl chr13:67,184,402...67,454,019
G
Ramp1
receptor activity modifying protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RAMP1 mRNA
CTD
PMID:20044591
NCBI chr 9:99,213,031...99,263,696
G
Ranbp1
RAN binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RANBP1 mRNA
CTD
PMID:20044591
NCBI chr11:96,246,912...96,255,145
Ensembl chr11:96,246,740...96,255,145
G
Ranbp9
RAN binding protein 9
affects expression
ISO
Vitamin K 3 affects the expression of RANBP9 mRNA
CTD
PMID:23410634
NCBI chr17:21,426,717...21,508,964
Ensembl chr17:21,426,777...21,508,964
G
Rap1gap
Rap1 GTPase-activating protein
increases expression
ISO
Vitamin K 3 results in increased expression of RAP1GAP mRNA
CTD
PMID:23410634
NCBI chr 5:155,157,511...155,222,622
Ensembl chr 5:155,157,558...155,222,622
G
Rasd1
ras related dexamethasone induced 1
affects expression
ISO
Vitamin K 3 affects the expression of RASD1 mRNA
CTD
PMID:20044591
NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710
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Rasl11a
RAS-like family 11 member A
affects expression
ISO
Vitamin K 3 affects the expression of RASL11A mRNA
CTD
PMID:20044591
NCBI chr12:13,372,023...13,374,784
Ensembl chr12:13,372,023...13,376,451
G
Rassf1
Ras association domain family member 1
affects expression
ISO
Vitamin K 3 affects the expression of RASSF1 mRNA
CTD
PMID:20044591
NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805
G
Rb1
RB transcriptional corepressor 1
increases expression
ISO
Vitamin K 3 results in increased expression of RB1 mRNA
CTD
PMID:16010434
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
G
Rbbp4
RB binding protein 4, chromatin remodeling factor
affects expression
ISO
Vitamin K 3 affects the expression of RBBP4 mRNA
CTD
PMID:20829426
NCBI chr 5:146,940,207...146,959,501
Ensembl chr 5:146,922,611...146,959,501
G
Rbbp6
RB binding protein 6, ubiquitin ligase
affects expression
ISO
Vitamin K 3 affects the expression of RBBP6 mRNA
CTD
PMID:20044591
NCBI chr 1:186,934,563...186,966,852
Ensembl chr 1:186,934,938...186,966,852
G
Rbm17
RNA binding motif protein 17
affects expression
ISO
Vitamin K 3 affects the expression of RBM17 mRNA
CTD
PMID:20044591
NCBI chr17:71,846,941...71,863,834
Ensembl chr17:71,846,916...71,864,431
G
Rbms1
RNA binding motif, single stranded interacting protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RBMS1 mRNA
CTD
PMID:20044591
NCBI chr 3:65,604,475...65,829,072
Ensembl chr 3:65,606,358...65,829,013
G
Rbmx
RNA binding motif protein, X-linked
affects expression
ISO
Vitamin K 3 affects the expression of RBMX mRNA
CTD
PMID:20044591
NCBI chr X:140,342,544...140,352,121
Ensembl chr X:140,345,571...140,352,035
G
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
decreases expression
ISO
Vitamin K 3 results in decreased expression of RBPJ mRNA
CTD
PMID:25270620
NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307
G
Rcan1
regulator of calcineurin 1
increases phosphorylation
ISO
Vitamin K 3 results in increased phosphorylation of RCAN1 protein
CTD
PMID:12927602
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
G
Rcn1
reticulocalbin 1
affects expression
ISO
Vitamin K 3 affects the expression of RCN1 mRNA
CTD
PMID:20044591
NCBI chr 3:112,295,838...112,310,082
Ensembl chr 3:112,295,838...112,310,082
G
Rcor3
REST corepressor 3
affects expression
ISO
Vitamin K 3 affects the expression of RCOR3 mRNA
CTD
PMID:23410634
NCBI chr13:106,156,166...106,196,542
Ensembl chr13:106,157,232...106,196,575
G
Reep1
receptor accessory protein 1
affects expression
ISO
Vitamin K 3 affects the expression of REEP1 mRNA
CTD
PMID:20044591
NCBI chr 4:105,303,974...105,420,611
Ensembl chr 4:105,303,969...105,420,602
G
Reep4
receptor accessory protein 4
affects expression
ISO
Vitamin K 3 affects the expression of REEP4 mRNA
CTD
PMID:23410634
NCBI chr15:52,030,022...52,033,229
Ensembl chr15:52,029,646...52,033,231
G
Reep6
receptor accessory protein 6
affects expression
ISO
Vitamin K 3 affects the expression of REEP6 mRNA
CTD
PMID:20044591
NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
Vitamin K 3 inhibits the reaction [TNF protein affects the localization of RELA protein]
CTD
PMID:20030669
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Relb
RELB proto-oncogene, NF-kB subunit
affects expression
ISO
Vitamin K 3 affects the expression of RELB mRNA
CTD
PMID:20044591
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
G
Retreg1
reticulophagy regulator 1
affects expression
ISO
Vitamin K 3 affects the expression of RETREG1 mRNA
CTD
PMID:20044591
NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356
G
Retreg2
reticulophagy regulator family member 2
affects expression
ISO
Vitamin K 3 affects the expression of RETREG2 mRNA
CTD
PMID:20044591
NCBI chr 9:84,088,935...84,095,072
Ensembl chr 9:84,088,964...84,094,837
G
Rex1bd
required for excision 1-B domain containing
affects expression
ISO
Vitamin K 3 affects the expression of REX1BD mRNA
CTD
PMID:20044591
NCBI chr16:18,956,023...18,958,494
Ensembl chr16:18,955,969...18,958,494
G
Rexo2
RNA exonuclease 2
affects expression
ISO
Vitamin K 3 affects the expression of REXO2 mRNA
CTD
PMID:20044591
NCBI chr 8:57,708,420...57,720,142
Ensembl chr 8:57,707,558...57,720,142
G
Rfc4
replication factor C subunit 4
affects expression
ISO
Vitamin K 3 affects the expression of RFC4 mRNA
CTD
PMID:20044591
NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730
G
Rgcc
regulator of cell cycle
affects expression
ISO
Vitamin K 3 affects the expression of RGCC mRNA
CTD
PMID:20044591
NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
G
Rgs16
regulator of G-protein signaling 16
affects expression
ISO
Vitamin K 3 affects the expression of RGS16 mRNA
CTD
PMID:20044591
NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313
G
Rgs3
regulator of G-protein signaling 3
affects expression
ISO
Vitamin K 3 affects the expression of RGS3 mRNA
CTD
PMID:23410634
NCBI chr 5:81,037,588...81,177,446
Ensembl chr 5:81,056,068...81,177,445
G
Rhbdd3
rhomboid domain containing 3
affects expression
ISO
Vitamin K 3 affects the expression of RHBDD3 mRNA
CTD
PMID:20044591
NCBI chr14:84,208,155...84,214,334
Ensembl chr14:84,209,432...84,214,332
G
Rhbg
Rh family B glycoprotein
affects expression
ISO
Vitamin K 3 affects the expression of RHBG mRNA
CTD
PMID:20044591
NCBI chr 2:176,002,886...176,015,201
Ensembl chr 2:176,002,887...176,015,609
G
Rhoa
ras homolog family member A
multiple interactions decreases prenylation
ISO
tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 results in decreased prenylation of RHOA protein]; Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]
CTD
PMID:21257924
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
G
Rhoc
ras homolog family member C
affects expression
ISO
Vitamin K 3 affects the expression of RHOC mRNA
CTD
PMID:20044591
NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745
G
Ribc2
RIB43A domain with coiled-coils 2
affects expression
ISO
Vitamin K 3 affects the expression of RIBC2 mRNA
CTD
PMID:20044591
NCBI chr 7:118,122,722...118,137,772
Ensembl chr 7:118,122,408...118,137,767
G
Rictor
RPTOR independent companion of MTOR, complex 2
affects expression
ISO
Vitamin K 3 affects the expression of RICTOR mRNA
CTD
PMID:23410634
NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:57,539,311...57,631,288
G
Rita1
RBPJ interacting and tubulin associated 1
affects expression
ISO
Vitamin K 3 affects the expression of RITA1 mRNA
CTD
PMID:20044591
NCBI chr12:41,610,713...41,614,545
Ensembl chr12:41,610,877...41,614,541
G
Rmi2
RecQ mediated genome instability 2
affects expression
ISO
Vitamin K 3 affects the expression of RMI2 mRNA
CTD
PMID:20044591
NCBI chr10:5,336,269...5,344,202
Ensembl chr10:5,338,060...5,344,235
G
Rnf114
ring finger protein 114
affects expression
ISO
Vitamin K 3 affects the expression of RNF114 mRNA
CTD
PMID:20044591
NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960
G
Rnf122
ring finger protein 122
affects expression
ISO
Vitamin K 3 affects the expression of RNF122 mRNA
CTD
PMID:20044591
NCBI chr16:67,712,936...67,730,479
Ensembl chr16:67,712,936...67,730,479
G
Rnf128
ring finger protein 128
affects expression
ISO
Vitamin K 3 affects the expression of RNF128 mRNA
CTD
PMID:20044591
NCBI chr X:107,968,973...108,087,037
Ensembl chr X:107,972,348...108,087,288
G
Rnf130
ring finger protein 130
affects expression
ISO
Vitamin K 3 affects the expression of RNF130 mRNA
CTD
PMID:20044591
NCBI chr10:34,843,920...34,957,130
Ensembl chr10:34,843,915...34,960,408
G
Rnf43
ring finger protein 43
affects expression
ISO
Vitamin K 3 affects the expression of RNF43 mRNA
CTD
PMID:20044591
NCBI chr10:72,958,744...73,034,540
Ensembl chr10:72,961,641...73,034,551
G
Rnf44
ring finger protein 44
affects expression
ISO
Vitamin K 3 affects the expression of RNF44 mRNA
CTD
PMID:20044591
NCBI chr17:9,925,100...9,939,496
Ensembl chr17:9,930,375...9,939,478
G
Rom1
retinal outer segment membrane protein 1
affects expression
ISO
Vitamin K 3 affects the expression of ROM1 mRNA
CTD
PMID:20044591
NCBI chr 1:215,253,155...215,255,163
Ensembl chr 1:215,253,159...215,255,163
G
Rpa1
replication protein A1
affects expression
ISO
Vitamin K 3 affects the expression of RPA1 mRNA
CTD
PMID:20044591
NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279
G
Rpgr
retinitis pigmentosa GTPase regulator
affects expression
ISO
Vitamin K 3 affects the expression of RPGR mRNA
CTD
PMID:23410634
NCBI chr X:15,238,961...15,299,004
Ensembl chr X:15,239,159...15,298,999
G
Rpl27a
ribosomal protein L27A
affects expression
ISO
Vitamin K 3 affects the expression of RPL27A mRNA
CTD
PMID:23410634
NCBI chr 1:172,971,957...172,977,591
G
Rpp25l
ribonuclease P/MRP subunit p25 like
affects expression
ISO
Vitamin K 3 affects the expression of RPP25L mRNA
CTD
PMID:20044591
NCBI chr 5:61,674,299...61,675,844
Ensembl chr 5:61,672,199...61,675,168
G
Rps6ka3
ribosomal protein S6 kinase A3
affects expression
ISO
Vitamin K 3 affects the expression of RPS6KA3 mRNA
CTD
PMID:20044591
NCBI chr X:39,325,926...39,432,017
Ensembl chr X:39,325,926...39,433,678
G
Rptor
regulatory associated protein of MTOR, complex 1
affects expression
ISO
Vitamin K 3 affects the expression of RPTOR mRNA
CTD
PMID:20044591
NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413
G
Rras2
RAS related 2
increases expression
ISO
Vitamin K 3 results in increased expression of RRAS2 mRNA
CTD
PMID:23410634
NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
G
Rrbp1
ribosome binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RRBP1 mRNA
CTD
PMID:20044591
NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255
G
Rrm1
ribonucleotide reductase catalytic subunit M1
affects expression
ISO
Vitamin K 3 affects the expression of RRM1 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944
G
Rsad1
radical S-adenosyl methionine domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of RSAD1 mRNA
CTD
PMID:20044591
NCBI chr10:79,980,817...79,996,493
Ensembl chr10:79,982,203...79,996,447
G
Rsrp1
arginine and serine rich protein 1
affects expression
ISO
Vitamin K 3 affects the expression of RSRP1 mRNA
CTD
PMID:20044591
NCBI chr 5:152,431,448...152,435,202
Ensembl chr 5:152,431,478...152,435,126
G
RT1-A2
RT1 class Ia, locus A2
affects expression
ISO
Vitamin K 3 affects the expression of HLA-E mRNA
CTD
PMID:20044591
NCBI chr20:4,872,720...4,876,425
G
RT1-Ba
RT1 class II, locus Ba
affects expression
ISO
Vitamin K 3 affects the expression of HLA-DQA1 mRNA
CTD
PMID:20829426
NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653
G
RT1-Bb
RT1 class II, locus Bb
affects expression
ISO
Vitamin K 3 affects the expression of HLA-DQB1 mRNA
CTD
PMID:20829426
NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118
G
Rtl6
retrotransposon Gag like 6
affects expression
ISO
Vitamin K 3 affects the expression of RTL6 mRNA
CTD
PMID:20044591
NCBI chr 7:117,564,780...117,569,865
Ensembl chr 7:117,563,239...117,570,129
G
Rusf1
RUS family member 1
affects expression
ISO
Vitamin K 3 affects the expression of RUSF1 mRNA
CTD
PMID:20044591
NCBI chr 1:192,282,708...192,312,119
Ensembl chr 1:192,282,711...192,311,137
G
Rxra
retinoid X receptor alpha
affects expression
ISO
Vitamin K 3 affects the expression of RXRA mRNA
CTD
PMID:20044591
NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417
G
Ryr1
ryanodine receptor 1
affects expression
ISO
Vitamin K 3 affects the expression of RYR1 mRNA
CTD
PMID:20044591
NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305
G
S100a6
S100 calcium binding protein A6
affects expression
ISO
Vitamin K 3 affects the expression of S100A6 mRNA
CTD
PMID:20044591
NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762
G
Sapcd2
suppressor APC domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of SAPCD2 mRNA
CTD
PMID:23410634
NCBI chr 3:28,583,615...28,590,694
Ensembl chr 3:28,585,416...28,591,389
G
Sash1
SAM and SH3 domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of SASH1 mRNA
CTD
PMID:20044591
NCBI chr 1:4,940,207...5,238,777
Ensembl chr 1:4,940,207...5,238,530
G
Sc5d
sterol-C5-desaturase
affects expression
ISO
Vitamin K 3 affects the expression of SC5D mRNA
CTD
PMID:20044591
NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277
G
Scand1
SCAN domain-containing 1
affects expression
ISO
Vitamin K 3 affects the expression of SCAND1 mRNA
CTD
PMID:20044591
NCBI chr 3:165,278,723...165,279,587
Ensembl chr 3:165,278,723...165,279,587
G
Scap
SREBF chaperone
affects expression
ISO
Vitamin K 3 affects the expression of SCAP mRNA
CTD
PMID:20044591
NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075
G
Scrn2
secernin 2
affects expression
ISO
Vitamin K 3 affects the expression of SCRN2 mRNA
CTD
PMID:20044591
NCBI chr10:82,513,043...82,517,115
Ensembl chr10:82,507,955...82,517,114
G
Sec14l4
SEC14-like lipid binding 4
increases expression
ISO
Vitamin K 3 results in increased expression of SEC14L4 mRNA
CTD
PMID:25270620
NCBI chr14:83,136,335...83,152,382
Ensembl chr14:83,136,339...83,153,215
G
Sec24b
SEC24 homolog B, COPII coat complex component
affects expression
ISO
Vitamin K 3 affects the expression of SEC24B mRNA
CTD
PMID:23410634
NCBI chr 2:221,236,897...221,306,986
Ensembl chr 2:221,236,898...221,306,919
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Sec61g
Sec61 translocon subunit gamma
affects expression
ISO
Vitamin K 3 affects the expression of SEC61G mRNA
CTD
PMID:20044591
NCBI chr14:95,113,083...95,119,458
Ensembl chr 9:48,798,504...48,798,710 Ensembl chr14:48,798,504...48,798,710
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Sec63
SEC63 homolog, protein translocation regulator
affects expression
ISO
Vitamin K 3 affects the expression of SEC63 mRNA
CTD
PMID:20044591
NCBI chr20:47,827,291...47,896,248
Ensembl chr20:47,827,291...47,896,248
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Seh1l
SEH1-like nucleoporin
affects expression
ISO
Vitamin K 3 affects the expression of SEH1L mRNA
CTD
PMID:20044591
NCBI chr18:63,612,228...63,639,852
Ensembl chr18:63,616,768...63,639,840
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Selenop
selenoprotein P
affects expression
ISO
Vitamin K 3 affects the expression of SELENOP mRNA
CTD
PMID:20044591
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
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Selenos
selenoprotein S
affects expression
ISO
Vitamin K 3 affects the expression of SELENOS mRNA
CTD
PMID:20044591
NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:129,070,230...129,077,991
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Selenow
selenoprotein W
affects expression
ISO
Vitamin K 3 affects the expression of SELENOW mRNA
CTD
PMID:20044591
NCBI chr 1:85,727,631...85,732,703
Ensembl chr 1:85,727,632...85,732,703
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Sema4g
semaphorin 4G
affects expression
ISO
Vitamin K 3 affects the expression of SEMA4G mRNA
CTD
PMID:20044591
NCBI chr 1:253,799,552...253,814,504
Ensembl chr 1:253,800,099...253,814,503
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Sema6a
semaphorin 6A
affects expression
ISO
Vitamin K 3 affects the expression of SEMA6A mRNA
CTD
PMID:20044591
NCBI chr18:42,237,227...42,358,540
Ensembl chr18:42,237,228...42,358,540
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Sephs2
selenophosphate synthetase 2
affects expression
ISO
Vitamin K 3 affects the expression of SEPHS2 mRNA
CTD
PMID:20044591
NCBI chr 1:191,323,637...191,325,955
Ensembl chr 1:191,323,641...191,325,955
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Serbp1
Serpine1 mRNA binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of SERBP1 mRNA
CTD
PMID:20044591
NCBI chr 4:97,731,200...97,748,438
Ensembl chr 4:97,731,277...97,751,518
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Serpinb1a
serpin family B member 1A
affects expression
ISO
Vitamin K 3 affects the expression of SERPINB1 mRNA
CTD
PMID:20044591
NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,799,415...31,808,166
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Serpinb5
serpin family B member 5
increases expression
ISO
Vitamin K 3 results in increased expression of SERPINB5 mRNA
CTD
PMID:12414654
NCBI chr13:23,500,203...23,520,401
Ensembl chr13:23,500,198...23,520,400
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Setd6
SET domain containing 6, protein lysine methyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of SETD6 mRNA
CTD
PMID:20044591
NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515
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Sgk2
serum/glucocorticoid regulated kinase 2
affects expression
ISO
Vitamin K 3 affects the expression of SGK2 mRNA
CTD
PMID:23410634
NCBI chr 3:172,063,625...172,089,000
Ensembl chr 3:172,063,776...172,089,011
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Sh2d5
SH2 domain containing 5
affects expression
ISO
Vitamin K 3 affects the expression of SH2D5 mRNA
CTD
PMID:23410634
NCBI chr 5:155,753,087...155,763,936
Ensembl chr 5:155,750,803...155,763,936
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Sh3bgrl3
SH3 domain binding glutamate-rich protein like 3
affects expression
ISO
Vitamin K 3 affects the expression of SH3BGRL3 mRNA
CTD
PMID:20044591
NCBI chr 5:151,637,897...151,639,270
Ensembl chr 5:151,637,674...151,639,395
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Sh3pxd2a
SH3 and PX domains 2A
affects expression
ISO
Vitamin K 3 affects the expression of SH3PXD2A mRNA
CTD
PMID:20044591
NCBI chr 1:256,094,991...256,301,120
Ensembl chr 1:256,094,991...256,300,967
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Sh3rf1
SH3 domain containing ring finger 1
increases expression
ISO
Vitamin K 3 results in increased expression of SH3RF1 mRNA
CTD
PMID:25270620
NCBI chr16:33,746,396...33,912,127
Ensembl chr16:33,746,396...33,912,153
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Sh3yl1
SH3 and SYLF domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of SH3YL1 mRNA
CTD
PMID:20044591
NCBI chr 6:53,250,036...53,293,406
Ensembl chr 6:53,249,610...53,293,404
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Shank2
SH3 and multiple ankyrin repeat domains 2
affects expression
ISO
Vitamin K 3 affects the expression of SHANK2 mRNA
CTD
PMID:20044591
NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:208,598,772...209,018,736
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Siah1
siah E3 ubiquitin protein ligase 1
affects expression
ISO
Vitamin K 3 affects the expression of SIAH1 mRNA
CTD
PMID:23410634
NCBI chr19:36,552,165...36,575,773
Ensembl chr19:36,540,947...36,581,541
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Sidt2
SID1 transmembrane family, member 2
affects expression
ISO
Vitamin K 3 affects the expression of SIDT2 mRNA
CTD
PMID:20044591
NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:55,129,091...55,145,408
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Sik1
salt-inducible kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of SIK1 mRNA
CTD
PMID:20044591
NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698
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Sinhcaf
SIN3-HDAC complex associated factor
affects expression
ISO
Vitamin K 3 affects the expression of SINHCAF mRNA
CTD
PMID:20044591
NCBI chr 4:183,619,647...183,644,628
Ensembl chr 4:183,619,658...183,641,626
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Sirpa
signal-regulatory protein alpha
affects expression
ISO
Vitamin K 3 affects the expression of SIRPA mRNA
CTD
PMID:20044591
NCBI chr 3:137,272,932...137,311,279
Ensembl chr 3:137,273,042...137,311,279
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Sirt1
sirtuin 1
multiple interactions
ISO
[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite results in decreased degradation of SIRT1 mRNA]
CTD
PMID:24106086
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
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Ska3
spindle and kinetochore associated complex subunit 3
affects expression
ISO
Vitamin K 3 affects the expression of SKA3 mRNA
CTD
PMID:23410634
NCBI chr15:36,067,372...36,086,563
Ensembl chr15:36,067,373...36,086,563
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Skil
SKI-like proto-oncogene
decreases expression
ISO
Vitamin K 3 results in decreased expression of SKIL mRNA
CTD
PMID:25270620
NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:114,175,534...114,201,974
G
Slamf1
signaling lymphocytic activation molecule family member 1
increases expression
ISO
Vitamin K 3 results in increased expression of SLAMF1 mRNA
CTD
PMID:12414654
NCBI chr13:86,802,708...86,837,890
Ensembl chr13:86,802,708...86,837,890
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Slbp
stem-loop histone mRNA binding protein
affects expression
ISO
Vitamin K 3 affects the expression of SLBP mRNA
CTD
PMID:20044591
NCBI chr14:81,295,479...81,306,446
Ensembl chr14:81,296,223...81,306,447
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Slc10a3
solute carrier family 10, member 3
affects expression
ISO
Vitamin K 3 affects the expression of SLC10A3 mRNA
CTD
PMID:20044591
NCBI chr X:157,306,043...157,309,849
Ensembl chr X:157,303,915...157,309,793
G
Slc12a7
solute carrier family 12 member 7
affects expression
ISO
Vitamin K 3 affects the expression of SLC12A7 mRNA
CTD
PMID:20044591
NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957
G
Slc12a9
solute carrier family 12, member 9
affects expression
ISO
Vitamin K 3 affects the expression of SLC12A9 mRNA
CTD
PMID:20044591
NCBI chr12:25,005,741...25,022,628
Ensembl chr12:25,005,738...25,022,607
G
Slc15a4
solute carrier family 15 member 4
affects expression
ISO
Vitamin K 3 affects the expression of SLC15A4 mRNA
CTD
PMID:20044591
NCBI chr12:34,684,583...34,718,429
Ensembl chr12:34,698,955...34,719,819
G
Slc16a3
solute carrier family 16 member 3
affects expression
ISO
Vitamin K 3 affects the expression of SLC16A3 mRNA
CTD
PMID:20044591
NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903
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Slc17a2
solute carrier family 17, member 2
affects expression
ISO
Vitamin K 3 affects the expression of SLC17A2 mRNA
CTD
PMID:23410634
NCBI chr17:41,748,195...41,767,601
Ensembl chr17:41,748,195...41,764,180
G
Slc19a3
solute carrier family 19 member 3
affects expression
ISO
Vitamin K 3 affects the expression of SLC19A3 mRNA
CTD
PMID:20044591
NCBI chr 9:91,723,799...91,747,499
Ensembl chr 9:91,724,718...91,754,991
G
Slc1a1
solute carrier family 1 member 1
affects expression
ISO
Vitamin K 3 affects the expression of SLC1A1 mRNA
CTD
PMID:20044591
NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469
G
Slc20a1
solute carrier family 20 member 1
affects expression
ISO
Vitamin K 3 affects the expression of SLC20A1 mRNA
CTD
PMID:20044591
NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249
G
Slc20a2
solute carrier family 20 member 2
affects expression
ISO
Vitamin K 3 affects the expression of SLC20A2 mRNA
CTD
PMID:20044591
NCBI chr16:76,163,315...76,253,881
Ensembl chr16:76,162,922...76,253,881
G
Slc22a23
solute carrier family 22, member 23
affects expression
ISO
Vitamin K 3 affects the expression of SLC22A23 mRNA
CTD
PMID:20044591
NCBI chr17:30,749,445...30,915,139
Ensembl chr17:30,749,445...30,915,139
G
Slc22a3
solute carrier family 22 member 3
affects expression
ISO
Vitamin K 3 affects the expression of SLC22A3 mRNA
CTD
PMID:23410634
NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353
G
Slc25a3
solute carrier family 25 member 3
affects expression
ISO
Vitamin K 3 affects the expression of SLC25A3 mRNA
CTD
PMID:20044591
NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
G
Slc25a36
solute carrier family 25 member 36
affects expression
ISO
Vitamin K 3 affects the expression of SLC25A36 mRNA
CTD
PMID:20044591
NCBI chr 8:106,539,355...106,573,240
G
Slc25a5
solute carrier family 25 member 5
affects expression
ISO
Vitamin K 3 affects the expression of SLC25A5 mRNA
CTD
PMID:20044591
NCBI chr X:120,897,616...120,900,683
Ensembl chr X:120,897,563...120,900,688
G
Slc26a2
solute carrier family 26 member 2
affects expression
ISO
Vitamin K 3 affects the expression of SLC26A2 mRNA
CTD
PMID:20044591
NCBI chr18:56,918,662...56,937,032
Ensembl chr18:56,923,337...56,937,012
G
Slc27a2
solute carrier family 27 member 2
affects expression
ISO
Vitamin K 3 affects the expression of SLC27A2 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
G
Slc2a1
solute carrier family 2 member 1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of SLC2A1 mRNA Vitamin K 3 results in decreased expression of SLC2A1 mRNA
CTD
PMID:20044591 PMID:25270620
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
G
Slc2a3
solute carrier family 2 member 3
decreases expression
ISO
Vitamin K 3 results in decreased expression of SLC2A3 mRNA
CTD
PMID:25270620
NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186
G
Slc2a4rg
SLC2A4 regulator
affects expression
ISO
Vitamin K 3 affects the expression of SLC2A4RG mRNA
CTD
PMID:20044591
NCBI chr 3:188,871,509...188,874,652
G
Slc38a10
solute carrier family 38, member 10
affects expression
ISO
Vitamin K 3 affects the expression of SLC38A10 mRNA
CTD
PMID:20044591
NCBI chr10:105,885,250...105,935,043
Ensembl chr10:105,885,250...105,935,043
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Slc39a13
solute carrier family 39 member 13
affects expression
ISO
Vitamin K 3 affects the expression of SLC39A13 mRNA
CTD
PMID:20044591
NCBI chr 3:97,495,229...97,504,279
Ensembl chr 3:97,495,229...97,505,052
G
Slc39a14
solute carrier family 39 member 14
affects expression
ISO
Vitamin K 3 affects the expression of SLC39A14 mRNA
CTD
PMID:20044591
NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229
G
Slc44a4
solute carrier family 44, member 4
affects expression
ISO
Vitamin K 3 affects the expression of SLC44A4 mRNA
CTD
PMID:23410634
NCBI chr20:3,907,737...3,923,911
Ensembl chr20:3,907,737...3,923,854
G
Slc6a14
solute carrier family 6 member 14
affects expression
ISO
Vitamin K 3 affects the expression of SLC6A14 mRNA
CTD
PMID:23410634
NCBI chr X:117,109,063...117,169,522
Ensembl chr X:117,108,947...117,169,828
G
Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Vitamin K 3 results in increased expression of SLC7A11 mRNA
CTD
PMID:12414654 PMID:23410634
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
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Slmap
sarcolemma associated protein
affects expression
ISO
Vitamin K 3 affects the expression of SLMAP mRNA
CTD
PMID:20829426
NCBI chr16:1,673,964...1,791,902
Ensembl chr16:1,673,964...1,791,902
G
Slx9
SLX9 ribosome biogenesis factor
affects expression
ISO
Vitamin K 3 affects the expression of SLX9 mRNA
CTD
PMID:20044591
NCBI chr20:11,114,214...11,147,112
Ensembl chr20:11,114,214...11,147,085
G
Smad3
SMAD family member 3
affects expression
ISO
Vitamin K 3 affects the expression of SMAD3 mRNA
CTD
PMID:20044591
NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
G
Smarcc2
SWI/SNF related BAF chromatin remodeling complex subunit C2
affects expression
ISO
Vitamin K 3 affects the expression of SMARCC2 mRNA
CTD
PMID:20044591
NCBI chr 7:1,466,223...1,494,627
Ensembl chr 7:1,466,454...1,494,626
G
Smc1a
structural maintenance of chromosomes 1A
affects expression
ISO
Vitamin K 3 affects the expression of SMC1A mRNA
CTD
PMID:20044591 PMID:20829426
NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462
G
Smc4
structural maintenance of chromosomes 4
affects expression
ISO
Vitamin K 3 affects the expression of SMC4 mRNA
CTD
PMID:23410634
NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:155,550,262...155,581,937
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Smim19
small integral membrane protein 19
affects expression
ISO
Vitamin K 3 affects the expression of SMIM19 mRNA
CTD
PMID:23410634
NCBI chr16:76,245,838...76,266,786
Ensembl chr16:76,253,443...76,267,911
G
Smim29
small integral membrane protein 29
affects expression
ISO
Vitamin K 3 affects the expression of SMIM29 mRNA
CTD
PMID:20044591
NCBI chr20:5,620,686...5,622,730
Ensembl chr20:5,620,686...5,623,037
G
Smo
smoothened, frizzled class receptor
affects expression
ISO
Vitamin K 3 affects the expression of SMO mRNA
CTD
PMID:20044591
NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281
G
Smoc2
SPARC related modular calcium binding 2
affects expression
ISO
Vitamin K 3 affects the expression of SMOC2 mRNA
CTD
PMID:20044591
NCBI chr 1:63,935,627...64,064,952
Ensembl chr 1:63,935,647...64,064,955
G
Smox
spermine oxidase
affects expression
ISO
Vitamin K 3 affects the expression of SMOX mRNA
CTD
PMID:20044591
NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170 Ensembl chr X:139,184,798...139,220,170
G
Smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
affects expression
ISO
Vitamin K 3 affects the expression of SMPDL3A mRNA
CTD
PMID:20044591
NCBI chr20:37,679,004...37,701,979
Ensembl chr20:37,678,964...37,704,260
G
Smyd2
SET and MYND domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of SMYD2 mRNA
CTD
PMID:20044591
NCBI chr13:103,956,470...103,997,774
Ensembl chr13:103,956,473...103,997,774
G
Snai1
snail family transcriptional repressor 1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of SNAI1 mRNA Vitamin K 3 results in decreased expression of SNAI1 protein
CTD
PMID:20044591 PMID:31238027
NCBI chr 3:176,667,476...176,671,965
G
Snrnp200
small nuclear ribonucleoprotein U5 subunit 200
affects expression
ISO
Vitamin K 3 affects the expression of SNRNP200 mRNA
CTD
PMID:20044591
NCBI chr 3:134,882,173...134,911,512
Ensembl chr 3:134,882,173...134,911,500
G
Snrnp70
small nuclear ribonucleoprotein U1 subunit 70
affects expression
ISO
Vitamin K 3 affects the expression of SNRNP70 mRNA
CTD
PMID:20044591
NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851
G
Snrpd1
small nuclear ribonucleoprotein D1 polypeptide
affects expression
ISO
Vitamin K 3 affects the expression of SNRPD1 mRNA
CTD
PMID:20044591
NCBI chr18:1,969,351...1,980,207
Ensembl chr18:1,969,674...1,980,207
G
Snta1
syntrophin, alpha 1
affects expression
ISO
Vitamin K 3 affects the expression of SNTA1 mRNA
CTD
PMID:20044591
NCBI chr 3:163,336,509...163,366,954
Ensembl chr 3:163,336,516...163,366,927
G
Sntb1
syntrophin, beta 1
affects expression
ISO
Vitamin K 3 affects the expression of SNTB1 mRNA
CTD
PMID:20044591
NCBI chr 7:88,950,642...89,219,017
Ensembl chr 7:88,950,642...89,219,017
G
Snx14
sorting nexin 14
affects expression
ISO
Vitamin K 3 affects the expression of SNX14 mRNA
CTD
PMID:20044591
NCBI chr 8:98,053,769...98,278,287
Ensembl chr 8:98,186,714...98,270,451
G
Snx15
sorting nexin 15
decreases expression
ISO
Vitamin K 3 results in decreased expression of SNX15 mRNA
CTD
PMID:25270620
NCBI chr 1:212,846,308...212,855,450
Ensembl chr 1:212,846,312...212,855,450
G
Snx21
sorting nexin family member 21
affects expression
ISO
Vitamin K 3 affects the expression of SNX21 mRNA
CTD
PMID:20044591
NCBI chr 3:173,941,634...173,951,571
G
Snx9
sorting nexin 9
affects expression
ISO
Vitamin K 3 affects the expression of SNX9 mRNA
CTD
PMID:20044591
NCBI chr 1:48,827,061...48,915,215
Ensembl chr 1:48,830,053...48,915,214
G
Soat2
sterol O-acyltransferase 2
affects expression
ISO
Vitamin K 3 affects the expression of SOAT2 mRNA
CTD
PMID:20044591
NCBI chr 7:135,160,424...135,173,521
Ensembl chr 7:135,160,402...135,173,513
G
Sod1
superoxide dismutase 1
multiple interactions affects response to substance
ISO
[CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3 SOD1 protein affects the susceptibility to Vitamin K 3
CTD
PMID:10698074 PMID:12633745
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sod2
superoxide dismutase 2
decreases response to substance increases response to substance multiple interactions increases activity
ISO EXP
SOD2 protein results in decreased susceptibility to Vitamin K 3 SOD2 protein results in increased susceptibility to Vitamin K 3 [CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3 Vitamin K 3 results in increased activity of SOD2 protein Acetaminophen inhibits the reaction [Vitamin K 3 results in increased activity of SOD2 protein]
CTD
PMID:12633745 PMID:14660625 PMID:15986238 PMID:19265712
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
G
Sorl1
sortilin related receptor 1
affects expression
ISO
Vitamin K 3 affects the expression of SORL1 mRNA
CTD
PMID:20044591
NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:51,238,722...51,401,446
G
Sp5
Sp5 transcription factor
affects expression
ISO
Vitamin K 3 affects the expression of SP5 mRNA
CTD
PMID:20044591
NCBI chr 3:75,682,677...75,685,479
Ensembl chr 3:75,682,677...75,685,479
G
Spag5
sperm associated antigen 5
affects expression
ISO
Vitamin K 3 affects the expression of SPAG5 mRNA
CTD
PMID:20044591 PMID:23410634
NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
G
Spata20
spermatogenesis associated 20
affects expression
ISO
Vitamin K 3 affects the expression of SPATA20 mRNA
CTD
PMID:20044591
NCBI chr10:79,924,407...79,932,351
Ensembl chr10:79,924,330...79,931,250
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Spdl1
spindle apparatus coiled-coil protein 1
affects expression
ISO
Vitamin K 3 affects the expression of SPDL1 mRNA
CTD
PMID:23410634
NCBI chr10:19,773,456...19,798,341
Ensembl chr10:19,773,457...19,798,297
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Sphk1
sphingosine kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of SPHK1 mRNA
CTD
PMID:20044591
NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
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Spink1
serine peptidase inhibitor, Kazal type 1
affects expression
ISO
Vitamin K 3 affects the expression of SPINK1 mRNA
CTD
PMID:20044591
NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545
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Spry2
sprouty RTK signaling antagonist 2
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of SPRY2 mRNA Vitamin K 3 results in decreased expression of SPRY2 mRNA
CTD
PMID:20044591 PMID:25270620
NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074
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Spry4
sprouty RTK signaling antagonist 4
affects expression
ISO
Vitamin K 3 affects the expression of SPRY4 mRNA
CTD
PMID:23410634
NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,687,039...30,704,173
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Spsb2
splA/ryanodine receptor domain and SOCS box containing 2
affects expression
ISO
Vitamin K 3 affects the expression of SPSB2 mRNA
CTD
PMID:20044591
NCBI chr 4:159,298,362...159,301,568
Ensembl chr 4:159,299,159...159,309,021
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Sqor
sulfide quinone oxidoreductase
affects expression
ISO
Vitamin K 3 affects the expression of SQOR mRNA
CTD
PMID:23410634
NCBI chr 3:130,294,783...130,341,655
Ensembl chr 3:130,292,814...130,340,799
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Sqstm1
sequestosome 1
increases expression
ISO
Vitamin K 3 results in increased expression of SQSTM1 mRNA
CTD
PMID:23410634 PMID:25270620
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Srgap2
SLIT-ROBO Rho GTPase activating protein 2
affects expression
ISO
Vitamin K 3 affects the expression of SRGAP2 mRNA
CTD
PMID:20044591
NCBI chr13:45,298,192...45,519,330
Ensembl chr13:45,298,192...45,519,330
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Sri
sorcin
affects expression
ISO
Vitamin K 3 affects the expression of SRI mRNA
CTD
PMID:20044591
NCBI chr 4:26,928,338...26,952,980
Ensembl chr 4:26,923,662...26,961,361
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Srpk1
SRSF protein kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of SRPK1 mRNA
CTD
PMID:20044591
NCBI chr20:6,647,539...6,684,129
Ensembl chr20:6,649,450...6,683,835
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Srrm2
serine/arginine repetitive matrix 2
affects expression
ISO
Vitamin K 3 affects the expression of SRRM2 mRNA
CTD
PMID:20044591
NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337
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Srsf11
serine and arginine rich splicing factor 11
affects expression
ISO
Vitamin K 3 affects the expression of SRSF11 mRNA
CTD
PMID:20044591
NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499
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Srxn1
sulfiredoxin 1
increases expression
ISO
Vitamin K 3 results in increased expression of SRXN1 mRNA
CTD
PMID:23410634 PMID:25270620
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
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Sst
somatostatin
decreases expression
ISO
Vitamin K 3 results in decreased expression of SST mRNA
CTD
PMID:12414654
NCBI chr11:90,461,546...90,462,823
Ensembl chr11:90,461,546...90,462,823
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St14
ST14 transmembrane serine protease matriptase
affects expression
ISO
Vitamin K 3 affects the expression of ST14 mRNA
CTD
PMID:20044591
NCBI chr 8:37,798,994...37,839,881
Ensembl chr 8:37,798,995...37,855,652
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
ISO
Vitamin K 3 affects the expression of ST3GAL6 mRNA
CTD
PMID:20044591
NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720
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Stag3
STAG3 cohesin complex component
increases expression
ISO
Vitamin K 3 results in increased expression of STAG3 mRNA
CTD
PMID:25270620
NCBI chr12:22,398,291...22,428,548
Ensembl chr12:22,398,295...22,428,557
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Stk36
serine/threonine kinase 36
increases expression
ISO
Vitamin K 3 results in increased expression of STK36 mRNA
CTD
PMID:25270620
NCBI chr 9:83,625,905...83,652,785
Ensembl chr 9:83,626,030...83,653,525
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Strap
serine/threonine kinase receptor associated protein
affects expression
ISO
Vitamin K 3 affects the expression of STRAP mRNA
CTD
PMID:20044591
NCBI chr 4:172,377,325...172,391,573
Ensembl chr 4:172,377,305...172,392,436
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Suox
sulfite oxidase
affects expression
ISO
Vitamin K 3 affects the expression of SUOX mRNA
CTD
PMID:23410634
NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235
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Susd1
sushi domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of SUSD1 mRNA
CTD
PMID:20044591
NCBI chr 5:78,952,781...79,076,121
Ensembl chr 5:78,952,781...79,070,781
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Susd6
sushi domain containing 6
affects expression
ISO
Vitamin K 3 affects the expression of SUSD6 mRNA
CTD
PMID:20044591
NCBI chr 6:106,130,183...106,262,900
Ensembl chr 6:106,169,118...106,262,900
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Syne3
spectrin repeat containing, nuclear envelope family member 3
affects expression
ISO
Vitamin K 3 affects the expression of SYNE3 mRNA
CTD
PMID:20044591
NCBI chr 6:129,637,644...129,729,542
Ensembl chr 6:129,641,123...129,729,509
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Tacc1
transforming, acidic coiled-coil containing protein 1
affects expression
ISO
Vitamin K 3 affects the expression of TACC1 mRNA
CTD
PMID:20044591
NCBI chr16:73,515,016...73,598,395
Ensembl chr16:73,514,889...73,598,394
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Tacc2
transforming, acidic coiled-coil containing protein 2
affects expression
ISO
Vitamin K 3 affects the expression of TACC2 mRNA
CTD
PMID:20044591
NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152
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Taf15
TATA-box binding protein associated factor 15
affects expression
ISO
Vitamin K 3 affects the expression of TAF15 mRNA
CTD
PMID:20044591
NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,770,430...68,802,458
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Tbc1d9b
TBC1 domain family member 9B
affects expression
ISO
Vitamin K 3 affects the expression of TBC1D9B mRNA
CTD
PMID:20044591
NCBI chr10:34,961,012...34,998,227
Ensembl chr10:34,960,996...34,998,213
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Tbl1xr1
TBL1X/Y related 1
affects expression
ISO
Vitamin K 3 affects the expression of TBL1XR1 mRNA
CTD
PMID:23410634
NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:106,730,665...106,857,989
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Tbx2
T-box transcription factor 2
affects expression
ISO
Vitamin K 3 affects the expression of TBX2 mRNA
CTD
PMID:20044591
NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275
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Tcf7l2
transcription factor 7 like 2
decreases expression
ISO
Vitamin K 3 results in decreased expression of TCF7L2 protein
CTD
PMID:31238027
NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225
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Tcof1
treacle ribosome biogenesis factor 1
affects expression
ISO
Vitamin K 3 affects the expression of TCOF1 mRNA
CTD
PMID:20044591
NCBI chr18:56,537,437...56,570,727
Ensembl chr18:56,537,437...56,570,727
G
Tead4
TEA domain transcription factor 4
affects expression
ISO
Vitamin K 3 affects the expression of TEAD4 mRNA
CTD
PMID:23410634
NCBI chr 4:163,180,192...163,258,342
Ensembl chr 4:163,180,192...163,258,479
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Tecpr2
tectonin beta-propeller repeat containing 2
affects expression
ISO
Vitamin K 3 affects the expression of TECPR2 mRNA
CTD
PMID:20044591
NCBI chr 6:135,720,765...135,823,187
Ensembl chr 6:135,720,656...135,823,187
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Tenm3
teneurin transmembrane protein 3
affects expression
ISO
Vitamin K 3 affects the expression of TENM3 mRNA
CTD
PMID:20044591
NCBI chr16:47,984,732...50,711,352
Ensembl chr16:49,829,750...50,711,352
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Tent2
terminal nucleotidyltransferase 2
affects expression
ISO
Vitamin K 3 affects the expression of TENT2 mRNA
CTD
PMID:23410634
NCBI chr 2:26,115,150...26,167,465
Ensembl chr 2:26,115,240...26,167,113
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Tepsin
TEPSIN, adaptor related protein complex 4 accessory protein
affects expression
ISO
Vitamin K 3 affects the expression of TEPSIN mRNA
CTD
PMID:20044591
NCBI chr10:105,872,363...105,879,731
Ensembl chr10:105,872,366...105,880,209
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Tesk1
testis associated actin remodelling kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of TESK1 mRNA
CTD
PMID:20044591
NCBI chr 5:62,487,763...62,493,492
Ensembl chr 5:62,487,763...62,493,492
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Tfap2c
transcription factor AP-2 gamma
increases expression
ISO
Vitamin K 3 results in increased expression of TFAP2C mRNA
CTD
PMID:25270620
NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:181,733,419...181,741,404
G
Tfe3
transcription factor binding to IGHM enhancer 3
affects expression
ISO
Vitamin K 3 affects the expression of TFE3 mRNA
CTD
PMID:20044591
NCBI chr X:17,401,466...17,414,829
Ensembl chr X:17,401,466...17,414,685
G
Tff1
trefoil factor 1
affects expression
ISO
Vitamin K 3 affects the expression of TFF1 mRNA
CTD
PMID:20044591
NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956
G
Tff3
trefoil factor 3
affects expression
ISO
Vitamin K 3 affects the expression of TFF3 mRNA
CTD
PMID:20044591
NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,194,626...9,199,333
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Tfrc
transferrin receptor
affects expression
ISO
Vitamin K 3 affects the expression of TFRC mRNA
CTD
PMID:20044591
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
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Tgfb1i1
transforming growth factor beta 1 induced transcript 1
affects expression
ISO
Vitamin K 3 affects the expression of TGFB1I1 mRNA
CTD
PMID:23410634
NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903
G
Tgfbr2
transforming growth factor, beta receptor 2
affects expression
ISO
Vitamin K 3 affects the expression of TGFBR2 mRNA
CTD
PMID:20044591
NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469
G
Thap1
THAP domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of THAP1 mRNA
CTD
PMID:23410634
NCBI chr16:72,608,096...72,612,690
Ensembl chr16:72,607,305...72,612,690
G
Thap4
THAP domain containing 4
affects expression
ISO
Vitamin K 3 affects the expression of THAP4 mRNA
CTD
PMID:20044591
NCBI chr 9:101,689,935...101,729,656
Ensembl chr 9:101,689,936...101,729,441
G
Thra
thyroid hormone receptor alpha
affects expression
ISO
Vitamin K 3 affects the expression of THRA mRNA
CTD
PMID:20044591
NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
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Ticam1
TIR domain containing adaptor molecule 1
affects expression
ISO
Vitamin K 3 affects the expression of TICAM1 mRNA
CTD
PMID:20044591
NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892
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Timeless
timeless circadian regulator
affects expression
ISO
Vitamin K 3 affects the expression of TIMELESS mRNA
CTD
PMID:20044591
NCBI chr 7:1,239,388...1,263,344
Ensembl chr 7:1,239,450...1,263,337
G
Timm22
translocase of inner mitochondrial membrane 22
affects expression
ISO
Vitamin K 3 affects the expression of TIMM22 mRNA
CTD
PMID:20044591
NCBI chr10:61,751,686...61,759,444
Ensembl chr10:61,751,666...61,760,850
G
Timm23
translocase of inner mitochondrial membrane 23
affects expression
ISO
Vitamin K 3 affects the expression of TIMM23 mRNA
CTD
PMID:20044591
NCBI chr16:7,416,590...7,442,681
Ensembl chr16:7,416,597...7,442,658 Ensembl chr 3:7,416,597...7,442,658 Ensembl chr 6:7,416,597...7,442,658
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Timm9
translocase of inner mitochondrial membrane 9
affects expression
ISO
Vitamin K 3 affects the expression of TIMM9 mRNA
CTD
PMID:20044591
NCBI chr 6:95,346,065...95,358,895
Ensembl chr 6:95,346,065...95,358,895
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Timp2
TIMP metallopeptidase inhibitor 2
affects expression
ISO
Vitamin K 3 affects the expression of TIMP2 mRNA
CTD
PMID:20044591
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
affects expression
ISO
Vitamin K 3 affects the expression of TIPARP mRNA
CTD
PMID:20044591 PMID:20829426
NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:152,063,751...152,090,406
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Tjp1
tight junction protein 1
increases expression
ISO
Vitamin K 3 results in increased expression of TJP1 protein
CTD
PMID:31238027
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
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Tjp2
tight junction protein 2
affects expression
ISO
Vitamin K 3 affects the expression of TJP2 mRNA
CTD
PMID:20044591
NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:231,136,243...231,264,750
G
Tk1
thymidine kinase 1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of TK1 mRNA Vitamin K 3 results in decreased expression of TK1 mRNA
CTD
PMID:12414654 PMID:20044591
NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228
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Tlk1
tousled-like kinase 1
affects expression
ISO
Vitamin K 3 affects the expression of TLK1 mRNA
CTD
PMID:20829426
NCBI chr 3:75,928,303...76,035,246
Ensembl chr 3:75,928,303...76,035,059
G
Tm2d3
TM2 domain containing 3
affects expression
ISO
Vitamin K 3 affects the expression of TM2D3 mRNA
CTD
PMID:20044591
NCBI chr 1:128,677,680...128,687,580
Ensembl chr 1:128,677,629...128,687,580
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Tm7sf2
transmembrane 7 superfamily member 2
affects expression
ISO
Vitamin K 3 affects the expression of TM7SF2 mRNA
CTD
PMID:20044591
NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557
G
Tmed10
transmembrane p24 trafficking protein 10
affects expression
ISO
Vitamin K 3 affects the expression of TMED10 mRNA
CTD
PMID:20044591
NCBI chr 6:110,722,887...110,757,743
Ensembl chr 6:110,722,889...110,757,777
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Tmem125
transmembrane protein 125
affects expression
ISO
Vitamin K 3 affects the expression of TMEM125 mRNA
CTD
PMID:20044591
NCBI chr 5:137,348,545...137,349,949
Ensembl chr 5:137,345,202...137,351,952
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Tmem177
transmembrane protein 177
affects expression
ISO
Vitamin K 3 affects the expression of TMEM177 mRNA
CTD
PMID:20044591
NCBI chr13:33,576,704...33,580,129
Ensembl chr13:33,574,281...33,582,159
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Tmem18
transmembrane protein 18
affects expression
ISO
Vitamin K 3 affects the expression of TMEM18 mRNA
CTD
PMID:20044591
NCBI chr 6:52,934,419...52,941,868
Ensembl chr 6:52,934,419...52,941,866
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Tmem237
transmembrane protein 237
affects expression
ISO
Vitamin K 3 affects the expression of TMEM237 mRNA
CTD
PMID:20044591
NCBI chr 9:68,027,481...68,066,731
Ensembl chr 9:68,030,664...68,063,525
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Tmem245
transmembrane protein 245
affects expression
ISO
Vitamin K 3 affects the expression of TMEM245 mRNA
CTD
PMID:20044591
NCBI chr 5:76,366,157...76,443,108
Ensembl chr 5:76,366,157...76,442,888
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Tmem37
transmembrane protein 37
affects expression
ISO
Vitamin K 3 affects the expression of TMEM37 mRNA
CTD
PMID:20044591
NCBI chr13:33,737,096...33,743,602
Ensembl chr13:33,736,308...33,743,747
G
Tmem42
transmembrane protein 42
affects expression
ISO
Vitamin K 3 affects the expression of TMEM42 mRNA
CTD
PMID:20044591
NCBI chr 8:131,551,616...131,554,749
Ensembl chr 8:131,552,257...131,555,765
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Tmem45b
transmembrane protein 45b
affects expression
ISO
Vitamin K 3 affects the expression of TMEM45B mRNA
CTD
PMID:20044591
NCBI chr 8:38,123,423...38,168,599
Ensembl chr 8:38,123,423...38,168,599
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Tmem79
transmembrane protein 79
affects expression
ISO
Vitamin K 3 affects the expression of TMEM79 mRNA
CTD
PMID:20044591
NCBI chr 2:176,096,092...176,100,996
Ensembl chr 2:176,096,092...176,100,870
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Tmpo
thymopoietin
decreases expression
ISO
Vitamin K 3 results in decreased expression of TMPO mRNA
CTD
PMID:12414654
NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937
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Tmprss13
transmembrane serine protease 13
affects expression
ISO
Vitamin K 3 affects the expression of TMPRSS13 mRNA
CTD
PMID:20044591
NCBI chr 8:54,522,069...54,550,673
Ensembl chr 8:54,522,443...54,550,670
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Tmtc4
transmembrane O-mannosyltransferase targeting cadherins 4
affects expression
ISO
Vitamin K 3 affects the expression of TMTC4 mRNA
CTD
PMID:20044591
NCBI chr15:106,406,795...106,463,226
Ensembl chr15:106,407,597...106,463,210
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Tnf
tumor necrosis factor
multiple interactions increases secretion increases expression
EXP ISO
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of TNF mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of TNF protein] Vitamin K 3 inhibits the reaction [Lipopolysaccharides affects the localization of TNF protein]; Vitamin K 3 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] [Asbestos, Amosite co-treated with TNF protein] results in increased susceptibility to Vitamin K 3; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3; Vitamin K 3 inhibits the reaction [TNF protein affects the localization of RELA protein]; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]
CTD
PMID:8817062 PMID:19265712 PMID:19362101 PMID:20030669
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfrsf11b
TNF receptor superfamily member 11B
increases expression
ISO
Vitamin K 3 results in increased expression of TNFRSF11B mRNA
CTD
PMID:19675304
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
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Tnfrsf12a
TNF receptor superfamily member 12A
affects expression
ISO
Vitamin K 3 affects the expression of TNFRSF12A mRNA
CTD
PMID:20044591
NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704
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Tnfrsf19
TNF receptor superfamily member 19
affects expression
ISO
Vitamin K 3 affects the expression of TNFRSF19 mRNA
CTD
PMID:20829426
NCBI chr15:39,268,305...39,334,566
Ensembl chr15:39,268,305...39,356,438
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Tnfsf11
TNF superfamily member 11
decreases expression
ISO
Vitamin K 3 results in decreased expression of TNFSF11 mRNA
CTD
PMID:19675304
NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
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Tnxb
tenascin XB
affects expression
ISO
Vitamin K 3 affects the expression of TNXB mRNA
CTD
PMID:20044591
Ensembl chr20:4,031,082...4,090,128
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Tom1
target of myb1 membrane trafficking protein
increases expression
ISO
Vitamin K 3 results in increased expression of TOM1 mRNA
CTD
PMID:12414654
NCBI chr19:13,411,227...13,446,129
Ensembl chr19:13,411,157...13,446,110
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Tomm22
translocase of outer mitochondrial membrane 22
affects expression
ISO
Vitamin K 3 affects the expression of TOMM22 mRNA
CTD
PMID:20044591
NCBI chr 7:113,103,863...113,109,056
Ensembl chr 7:113,103,860...113,109,053
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Top1
DNA topoisomerase I
affects expression
ISO
Vitamin K 3 affects the expression of TOP1 mRNA
CTD
PMID:20044591
NCBI chr 3:169,713,195...169,796,330
Ensembl chr 3:169,713,130...169,796,327
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Top2a
DNA topoisomerase II alpha
affects expression
ISO
Vitamin K 3 affects the expression of TOP2A mRNA
CTD
PMID:20044591
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
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Top2b
DNA topoisomerase II beta
affects expression
ISO
Vitamin K 3 affects the expression of TOP2B mRNA
CTD
PMID:20044591
NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464
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Tp53
tumor protein p53
multiple interactions affects activity increases expression
ISO
[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein; EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of TP53 protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein] Vitamin K 3 affects the activity of TP53 protein
CTD
PMID:19082730 PMID:21533478 PMID:25005833 PMID:35435491
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tpx2
TPX2, microtubule nucleation factor
affects expression
ISO
Vitamin K 3 affects the expression of TPX2 mRNA
CTD
PMID:20044591
NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
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Tradd
TNFRSF1A-associated via death domain
affects expression
ISO
Vitamin K 3 affects the expression of TRADD mRNA
CTD
PMID:20044591
NCBI chr19:50,046,057...50,048,158
Ensembl chr19:50,046,061...50,052,550
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Traf3ip2
Traf3 interacting protein 2
affects expression
ISO
Vitamin K 3 affects the expression of TRAF3IP2 mRNA
CTD
PMID:20044591
NCBI chr20:44,565,992...44,609,240
Ensembl chr20:44,517,242...44,609,618
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Trem2
triggering receptor expressed on myeloid cells 2
affects expression
ISO
Vitamin K 3 affects the expression of TREM2 mRNA
CTD
PMID:20829426
NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779
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Trib3
tribbles pseudokinase 3
increases expression
ISO
Vitamin K 3 results in increased expression of TRIB3 mRNA
CTD
PMID:25270620
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802
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Trim14
tripartite motif-containing 14
affects expression
ISO
Vitamin K 3 affects the expression of TRIM14 mRNA
CTD
PMID:20044591
NCBI chr 5:65,596,149...65,620,434
Ensembl chr 5:65,596,149...65,620,434
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Trim2
tripartite motif-containing 2
affects expression
ISO
Vitamin K 3 affects the expression of TRIM2 mRNA
CTD
PMID:20044591
NCBI chr 2:171,798,654...171,950,193
Ensembl chr 2:171,798,660...171,913,468
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Trim26
tripartite motif-containing 26
affects expression
ISO
Vitamin K 3 affects the expression of TRIM26 mRNA
CTD
PMID:20044591
NCBI chr20:1,711,564...1,736,389
Ensembl chr20:1,715,005...1,736,623
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Trmt61a
tRNA methyltransferase 61A
affects expression
ISO
Vitamin K 3 affects the expression of TRMT61A mRNA
CTD
PMID:20044591
NCBI chr 6:136,558,417...136,564,411
Ensembl chr 6:136,558,391...136,564,410
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Trpa1
transient receptor potential cation channel, subfamily A, member 1
increases activity
ISO
Vitamin K 3 results in increased activity of TRPA1 protein
CTD
PMID:21591660
NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325
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Trrap
transformation/transcription domain-associated protein
affects expression
ISO
Vitamin K 3 affects the expression of TRRAP mRNA
CTD
PMID:20044591
NCBI chr12:14,851,758...14,941,444
Ensembl chr12:14,851,758...14,941,407
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Tsc22d2
TSC22 domain family, member 2
affects expression
ISO
Vitamin K 3 affects the expression of TSC22D2 mRNA
CTD
PMID:23410634
NCBI chr 2:144,796,760...144,847,930
Ensembl chr 2:144,796,841...144,843,559
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Tspan3
tetraspanin 3
affects expression
ISO
Vitamin K 3 affects the expression of TSPAN3 mRNA
CTD
PMID:20044591
NCBI chr 8:65,442,100...65,465,961
Ensembl chr 8:65,442,101...65,465,844
G
Tspan5
tetraspanin 5
affects expression
ISO
Vitamin K 3 affects the expression of TSPAN5 mRNA
CTD
PMID:20044591
NCBI chr 2:229,967,521...230,139,012
Ensembl chr 2:229,967,235...230,142,685
G
Tspan6
tetraspanin 6
affects expression
ISO
Vitamin K 3 affects the expression of TSPAN6 mRNA
CTD
PMID:20044591
NCBI chr X:101,385,686...101,395,371
Ensembl chr X:101,385,694...101,392,627
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Tspyl2
TSPY-like 2
affects expression
ISO
Vitamin K 3 affects the expression of TSPYL2 mRNA
CTD
PMID:20044591
NCBI chr X:24,918,851...24,924,462
Ensembl chr X:24,918,851...24,924,462
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Tst
thiosulfate sulfurtransferase
affects expression
ISO
Vitamin K 3 affects the expression of TST mRNA
CTD
PMID:20044591
NCBI chr 7:111,828,557...111,836,980
Ensembl chr 7:111,828,558...111,837,116
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Ttc3
tetratricopeptide repeat domain 3
affects expression
ISO
Vitamin K 3 affects the expression of TTC3 mRNA
CTD
PMID:20829426
NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418
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Tuba1a
tubulin, alpha 1A
decreases expression
ISO
Vitamin K 3 results in decreased expression of TUBA1A mRNA
CTD
PMID:12414654
NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035
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Tulp3
TUB like protein 3
affects expression
ISO
Vitamin K 3 affects the expression of TULP3 mRNA
CTD
PMID:20044591
NCBI chr 4:163,276,583...163,318,297
Ensembl chr 4:163,276,583...163,318,390
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Tulp4
TUB like protein 4
affects expression
ISO
Vitamin K 3 affects the expression of TULP4 mRNA
CTD
PMID:20044591
NCBI chr 1:49,082,492...49,218,262
Ensembl chr 1:49,087,886...49,218,250
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Twf2
twinfilin actin-binding protein 2
decreases expression
ISO
Vitamin K 3 results in decreased expression of TWF2 mRNA
CTD
PMID:25270620
NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:115,723,970...115,737,025
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Txnip
thioredoxin interacting protein
affects expression
ISO
Vitamin K 3 affects the expression of TXNIP mRNA
CTD
PMID:20044591
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
Vitamin K 3 results in increased expression of TXNRD1 mRNA
CTD
PMID:12414654
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
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Tyk2
tyrosine kinase 2
affects expression
ISO
Vitamin K 3 affects the expression of TYK2 mRNA
CTD
PMID:20044591
NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278
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Tyms
thymidylate synthetase
affects expression
ISO
Vitamin K 3 affects the expression of TYMS mRNA
CTD
PMID:20044591
NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097
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Ubb
ubiquitin B
affects expression
ISO
Vitamin K 3 affects the expression of UBB mRNA
CTD
PMID:20044591
NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335
G
Ubc
ubiquitin C
affects expression
ISO
Vitamin K 3 affects the expression of UBC mRNA
CTD
PMID:20044591
NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275
G
Ube2c
ubiquitin-conjugating enzyme E2C
decreases expression
ISO
Vitamin K 3 results in decreased expression of UBE2C mRNA
CTD
PMID:12414654
NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678
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Ubr4
ubiquitin protein ligase E3 component n-recognin 4
affects expression
ISO
Vitamin K 3 affects the expression of UBR4 mRNA
CTD
PMID:20044591
NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:156,919,085...157,027,127
G
Ucp2
uncoupling protein 2
affects expression
ISO
Vitamin K 3 affects the expression of UCP2 mRNA
CTD
PMID:20044591
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
G
Ugcg
UDP-glucose ceramide glucosyltransferase
affects expression
ISO
Vitamin K 3 affects the expression of UGCG mRNA
CTD
PMID:20829426
NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417
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Ugt1a6a
UDP glucuronosyltransferase family 1 member A6a
multiple interactions increases expression increases activity
EXP
Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter] Vitamin K 3 results in increased expression of UGT1A6 mRNA
CTD
PMID:15336321 PMID:22846377
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
G
Ugt1a7c
UDP glucuronosyltransferase 1 family, polypeptide A7C
increases expression
EXP
Vitamin K 3 results in increased expression of UGT1A7C mRNA
CTD
PMID:22846377
NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
affects expression
ISO
Vitamin K 3 affects the expression of UHRF1 mRNA
CTD
PMID:20044591
NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792
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Ung
uracil-DNA glycosylase
decreases expression
ISO
Vitamin K 3 results in decreased expression of UNG mRNA
CTD
PMID:12414654
NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257
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Upf3a
UPF3A, regulator of nonsense mediated mRNA decay
affects expression
ISO
Vitamin K 3 affects the expression of UPF3A mRNA
CTD
PMID:20044591
NCBI chr16:82,459,651...82,470,686
Ensembl chr16:82,459,906...82,470,686
G
Upp1
uridine phosphorylase 1
affects expression decreases expression
ISO
Vitamin K 3 affects the expression of UPP1 mRNA Vitamin K 3 results in decreased expression of UPP1 mRNA
CTD
PMID:20044591 PMID:25270620
NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034
G
Ush1c
USH1 protein network component harmonin
affects expression
ISO
Vitamin K 3 affects the expression of USH1C mRNA
CTD
PMID:20044591
NCBI chr 1:105,831,719...105,880,082
Ensembl chr 1:105,831,723...105,880,082
G
Ushbp1
USH1 protein network component harmonin binding protein 1
increases expression
ISO
Vitamin K 3 results in increased expression of USHBP1 mRNA
CTD
PMID:25270620
NCBI chr16:18,091,311...18,101,927
Ensembl chr16:18,091,316...18,101,867
G
Usp10
ubiquitin specific peptidase 10
affects expression
ISO
Vitamin K 3 affects the expression of USP10 mRNA
CTD
PMID:20044591
NCBI chr19:64,881,255...64,923,522
Ensembl chr19:64,881,315...64,923,519
G
Usp7
ubiquitin specific peptidase 7
affects expression
ISO
Vitamin K 3 affects the expression of USP7 mRNA
CTD
PMID:20044591
NCBI chr10:7,335,508...7,432,018
Ensembl chr10:7,367,604...7,432,013
G
Usp9x
ubiquitin specific peptidase 9, X-linked
affects expression
ISO
Vitamin K 3 affects the expression of USP9X mRNA
CTD
PMID:20044591
NCBI chr X:12,261,633...12,399,780
Ensembl chr X:12,261,633...12,369,491
G
Vars2
valyl-tRNA synthetase 2, mitochondrial
affects expression
ISO
Vitamin K 3 affects the expression of VARS2 mRNA
CTD
PMID:20044591
NCBI chr20:3,081,869...3,092,907
Ensembl chr20:3,081,893...3,092,901
G
Vasn
vasorin
affects expression
ISO
Vitamin K 3 affects the expression of VASN mRNA
CTD
PMID:20044591
NCBI chr10:11,424,174...11,434,681
Ensembl chr10:11,417,327...11,450,704
G
Vdac1
voltage-dependent anion channel 1
affects expression
ISO
Vitamin K 3 affects the expression of VDAC1 mRNA
CTD
PMID:20044591
NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
G
Vezf1
vascular endothelial zinc finger 1
affects expression
ISO
Vitamin K 3 affects the expression of VEZF1 mRNA
CTD
PMID:20044591
NCBI chr10:73,341,666...73,373,320
Ensembl chr10:73,356,985...73,373,320
G
Vgll4
vestigial-like family member 4
affects expression
ISO
Vitamin K 3 affects the expression of VGLL4 mRNA
CTD
PMID:20044591
NCBI chr 4:149,598,151...149,711,186
Ensembl chr 4:149,598,891...149,660,594
G
Vhl
von Hippel-Lindau tumor suppressor
multiple interactions
ISO
[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite results in decreased degradation of VHL mRNA]
CTD
PMID:24106086
NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:148,328,079...148,334,991
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Vim
vimentin
decreases expression
ISO
Vitamin K 3 results in decreased expression of VIM protein
CTD
PMID:31238027
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
G
Vkorc1l1
vitamin K epoxide reductase complex, subunit 1-like 1
affects expression
ISO
Vitamin K 3 affects the expression of VKORC1L1 mRNA
CTD
PMID:20044591
NCBI chr12:32,354,078...32,404,327
G
Vps28
VPS28 subunit of ESCRT-I
affects expression
ISO
Vitamin K 3 affects the expression of VPS28 mRNA
CTD
PMID:20044591
NCBI chr 7:110,222,638...110,226,486
Ensembl chr 7:110,222,638...110,225,569
G
Vps39
VPS39 subunit of HOPS complex
decreases expression
ISO
Vitamin K 3 results in decreased expression of VPS39 mRNA
CTD
PMID:25270620
NCBI chr 3:127,721,076...127,758,658
Ensembl chr 3:127,721,076...127,758,768
G
Vsnl1
visinin-like 1
affects expression
ISO
Vitamin K 3 affects the expression of VSNL1 mRNA
CTD
PMID:23410634
NCBI chr 6:39,757,721...39,878,556
Ensembl chr 6:39,757,722...39,878,556
G
Vtn
vitronectin
affects expression
ISO
Vitamin K 3 affects the expression of VTN mRNA
CTD
PMID:20044591
NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860
G
Vwa1
von Willebrand factor A domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of VWA1 mRNA
CTD
PMID:20044591
NCBI chr 5:171,659,694...171,664,880
Ensembl chr 5:171,659,698...171,664,880
G
Wbp1
WW domain binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of WBP1 mRNA
CTD
PMID:20044591
NCBI chr 4:117,182,880...117,185,279
Ensembl chr 4:117,182,880...117,185,326
G
Wdr3
WD repeat domain 3
affects expression
ISO
Vitamin K 3 affects the expression of WDR3 mRNA
CTD
PMID:20044591
NCBI chr 2:190,194,474...190,217,087
Ensembl chr 2:190,194,474...190,217,087
G
Wdr59
WD repeat domain 59
affects expression
ISO
Vitamin K 3 affects the expression of WDR59 mRNA
CTD
PMID:20044591
NCBI chr19:56,321,529...56,393,195
Ensembl chr19:56,325,438...56,393,132
G
Wdr81
WD repeat domain 81
affects expression
ISO
Vitamin K 3 affects the expression of WDR81 mRNA
CTD
PMID:20044591
NCBI chr10:60,780,268...60,793,671
Ensembl chr10:60,780,268...60,793,592
G
Wipi1
WD repeat domain, phosphoinositide interacting 1
affects expression
ISO
Vitamin K 3 affects the expression of WIPI1 mRNA
CTD
PMID:20044591
NCBI chr10:95,042,451...95,079,679
Ensembl chr10:95,042,441...95,079,293
G
Wwc1
WW and C2 domain containing 1
affects expression
ISO
Vitamin K 3 affects the expression of KIBRA mRNA
CTD
PMID:20044591
NCBI chr10:20,804,173...20,958,437
Ensembl chr10:20,799,237...20,958,437
G
Wwox
WW domain-containing oxidoreductase
affects expression
ISO
Vitamin K 3 affects the expression of WWOX mRNA
CTD
PMID:20044591
NCBI chr19:59,338,402...60,269,323
Ensembl chr19:59,341,233...60,269,441
G
Wwtr1
WW domain containing transcription regulator 1
increases expression
ISO
Vitamin K 3 results in increased expression of WWTR1 mRNA
CTD
PMID:25270620
NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950
G
Xbp1
X-box binding protein 1
affects expression
ISO
Vitamin K 3 affects the expression of XBP1 mRNA
CTD
PMID:20044591
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
G
Xist
X inactive specific transcript
affects expression
ISO
Vitamin K 3 affects the expression of XIST mRNA
CTD
PMID:20829426
NCBI chr X:72,540,753...72,558,266
G
Xpo1
exportin 1
affects expression
ISO
Vitamin K 3 affects the expression of XPO1 mRNA
CTD
PMID:20044591
NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714
G
Xpo5
exportin 5
affects expression
ISO
Vitamin K 3 affects the expression of XPO5 mRNA
CTD
PMID:20044591
NCBI chr 9:22,237,760...22,275,745
Ensembl chr 9:22,237,760...22,275,745
G
Yeats4
YEATS domain containing 4
affects expression
ISO
Vitamin K 3 affects the expression of YEATS4 mRNA
CTD
PMID:20044591
NCBI chr 7:54,744,220...54,751,361
Ensembl chr 7:54,744,221...54,751,361
G
Ykt6
YKT6 v-SNARE homolog
affects expression
ISO
Vitamin K 3 affects the expression of YKT6 mRNA
CTD
PMID:20044591
NCBI chr14:85,041,393...85,057,347
Ensembl chr14:85,046,164...85,057,346
G
Yrdc
yrdC N(6)-threonylcarbamoyltransferase domain containing
affects expression
ISO
Vitamin K 3 affects the expression of YRDC mRNA
CTD
PMID:20044591
NCBI chr 5:142,394,833...142,399,798
Ensembl chr 5:142,394,938...142,399,795
G
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
affects expression
ISO
Vitamin K 3 affects the expression of YWHAB mRNA
CTD
PMID:20044591
NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854
G
Zc3h12a
zinc finger CCCH type containing 12A
affects expression
ISO
Vitamin K 3 affects the expression of ZC3H12A mRNA
CTD
PMID:20044591
NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985
G
Zcchc14
zinc finger CCHC-type containing 14
affects expression
ISO
Vitamin K 3 affects the expression of ZCCHC14 mRNA
CTD
PMID:20044591
NCBI chr19:66,582,800...66,627,136
Ensembl chr19:66,582,800...66,627,136
G
Zeb1
zinc finger E-box binding homeobox 1
decreases expression
ISO
Vitamin K 3 results in decreased expression of ZEB1 protein
CTD
PMID:31238027
NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745
G
Zfand2a
zinc finger AN1-type containing 2A
affects expression
ISO
Vitamin K 3 affects the expression of ZFAND2A mRNA
CTD
PMID:20044591
NCBI chr12:20,275,435...20,286,513
Ensembl chr12:20,275,450...20,286,513
G
Zfhx3
zinc finger homeobox 3
affects expression
ISO
Vitamin K 3 affects the expression of ZFHX3 mRNA
CTD
PMID:20044591
NCBI chr19:52,789,146...53,795,664
Ensembl chr19:53,551,488...53,795,664
G
Zfp133
zinc finger protein 133
affects expression
ISO
Vitamin K 3 affects the expression of ZNF133 mRNA
CTD
PMID:20044591
NCBI chr 3:152,282,744...152,300,892
Ensembl chr 3:152,282,735...152,300,889
G
Zfp217
zinc finger protein 217
affects expression
ISO
Vitamin K 3 affects the expression of ZNF217 mRNA
CTD
PMID:23410634
NCBI chr 3:179,309,178...179,349,853
Ensembl chr 3:179,310,973...179,321,892
G
Zfp36l1
zinc finger protein 36, C3H type-like 1
affects expression
ISO
Vitamin K 3 affects the expression of ZFP36L1 mRNA
CTD
PMID:20044591
NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979
G
Zfp36l2
zinc finger protein 36, C3H type-like 2
affects expression
ISO
Vitamin K 3 affects the expression of ZFP36L2 mRNA
CTD
PMID:20044591
NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653
G
Zfp395
zinc finger protein 395
affects expression
ISO
Vitamin K 3 affects the expression of ZNF395 mRNA
CTD
PMID:20044591
NCBI chr15:43,757,350...43,797,513
Ensembl chr15:43,757,473...43,797,512
G
Zfp462
zinc finger protein 462
affects expression
ISO
Vitamin K 3 affects the expression of ZNF462 mRNA
CTD
PMID:20044591
NCBI chr 5:74,465,383...74,606,020
Ensembl chr 5:74,468,643...74,606,020
G
Zfp524
zinc finger protein 524
affects expression
ISO
Vitamin K 3 affects the expression of ZNF524 mRNA
CTD
PMID:20044591
NCBI chr 1:77,853,648...77,856,886
Ensembl chr 1:77,853,386...77,854,696
G
Zfp593
zinc finger protein 593
affects expression
ISO
Vitamin K 3 affects the expression of ZNF593 mRNA
CTD
PMID:20044591
NCBI chr 5:151,746,396...151,748,724
Ensembl chr 5:151,746,396...151,748,891
G
Zfp62
zinc finger protein 62
affects expression
ISO
Vitamin K 3 affects the expression of ZFP62 mRNA
CTD
PMID:20044591
NCBI chr10:34,019,367...34,040,564
Ensembl chr10:33,971,943...34,054,637
G
Zfp706
zinc finger protein 706
affects expression
ISO
Vitamin K 3 affects the expression of ZNF706 mRNA
CTD
PMID:20044591
NCBI chr 7:70,050,960...70,059,588
Ensembl chr 7:70,052,534...70,059,159
G
Zfp707
zinc finger protein 707
affects expression
ISO
Vitamin K 3 affects the expression of ZNF707 mRNA
CTD
PMID:20044591
NCBI chr 7:109,560,298...109,567,256
Ensembl chr 7:109,547,812...109,567,265
G
Zfp830
zinc finger protein 830
affects expression
ISO
Vitamin K 3 affects the expression of ZNF830 mRNA
CTD
PMID:20044591
NCBI chr10:68,198,903...68,200,367
Ensembl chr10:68,198,876...68,217,373
G
Zftraf1
zinc finger TRAF type containing 1
affects expression
ISO
Vitamin K 3 affects the expression of ZFTRAF1 mRNA
CTD
PMID:20044591
NCBI chr 7:110,244,634...110,258,071
Ensembl chr 7:110,244,634...110,261,078
G
Zfyve21
zinc finger FYVE-type containing 21
affects expression
ISO
Vitamin K 3 affects the expression of ZFYVE21 mRNA
CTD
PMID:20044591
NCBI chr 6:136,695,132...136,715,601
Ensembl chr 6:136,694,908...136,715,601
G
Zmiz1
zinc finger, MIZ-type containing 1
affects expression
ISO
Vitamin K 3 affects the expression of ZMIZ1 mRNA
CTD
PMID:20044591
NCBI chr16:1,033,983...1,239,425
Ensembl chr16:1,034,020...1,239,406
G
Znrd2
zinc ribbon domain containing 2
affects expression
ISO
Vitamin K 3 affects the expression of ZNRD2 mRNA
CTD
PMID:20044591
NCBI chr 1:212,447,010...212,448,793
Ensembl chr 1:212,447,010...212,448,793
G
Znrf1
zinc and ring finger 1
affects expression
ISO
Vitamin K 3 affects the expression of ZNRF1 mRNA
CTD
PMID:20044591
NCBI chr19:56,403,816...56,490,901
Ensembl chr19:56,405,728...56,490,881
G
Zswim3
zinc finger, SWIM-type containing 3
affects expression
ISO
Vitamin K 3 affects the expression of ZSWIM3 mRNA
CTD
PMID:20044591
NCBI chr 3:173,962,078...173,977,360
Ensembl chr 3:173,941,801...173,977,692
G
Zwint
ZW10 interacting kinetochore protein
affects expression
ISO
Vitamin K 3 affects the expression of ZWINT mRNA
CTD
PMID:20044591
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
G
Zyx
zyxin
affects expression
ISO
Vitamin K 3 affects the expression of ZYX mRNA
CTD
PMID:23410634
NCBI chr 4:72,203,991...72,213,181
Ensembl chr 4:72,204,007...72,213,181
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all