EC 5.3.* (intramolecular oxidoreductase) inhibitor - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	*EC 5.3. (intramolecular oxidoreductase) inhibitor**	go back to main search page
Accession:	CHEBI:76694	browse the term
Definition:	An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3..).
Synonyms:	related_synonym:	intramolecular oxidoreductase (EC 5.3.*) inhibitors; intramolecular oxidoreductase inhibitor; intramolecular oxidoreductase inhibitors

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Rat (1371) Mouse (1411) Human (1449) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (2) Green Monkey (0) Naked Mole-rat (0) All
Genes (1371)

amorolfine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

C-C motif chemokine ligand 5

multiple interactions

amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-X-C motif chemokine ligand 10

multiple interactions

amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

interleukin 4

multiple interactions

4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

potassium voltage-gated channel subfamily H member 2

decreases activity

amorolfine results in decreased activity of KCNH2 protein

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

NFKB inhibitor alpha

multiple interactions

amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

signal transducer and activator of transcription 1

multiple interactions

amorolfine inhibits the reaction [Biological Products results in increased phosphorylation of and results in increased activity of STAT1 protein]

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

thymic stromal lymphopoietin

multiple interactions

4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]

NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548

copper(II) chloride

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

decreases expression

cupric chloride results in decreased expression of AASDHPPT mRNA

NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966

G

ATP binding cassette subfamily A member 6

decreases expression

cupric chloride results in decreased expression of ABCA6 mRNA

NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530

G

ATP binding cassette subfamily C member 2

increases expression

cupric chloride results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

cupric chloride results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily F member 3

increases expression

cupric chloride results in increased expression of ABCF3 mRNA

NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

cupric chloride results in increased expression of ABHD4 mRNA

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

actin binding LIM protein family, member 3

increases expression

cupric chloride results in increased expression of ABLIM3 mRNA

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

ABR activator of RhoGEF and GTPase

increases expression

cupric chloride results in increased expression of ABR mRNA

NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505

G

acetyl-CoA carboxylase alpha

decreases expression

cupric chloride results in decreased expression of ACACA mRNA

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA acetyltransferase 2

decreases expression

cupric chloride results in decreased expression of ACAT2 mRNA

PMID:34921933 PMID:38568856

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

acetylcholinesterase

multiple interactions
decreases activity

cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein]
cupric chloride results in decreased activity of ACHE protein
Carnosine inhibits the reaction [cupric chloride results in decreased activity of ACHE protein]

PMID:24799335 PMID:32745495

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

aconitase 1

decreases expression

cupric chloride results in decreased expression of ACO1 protein

NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391

G

acyl-CoA synthetase family member 2

decreases expression

cupric chloride results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

decreases expression

cupric chloride results in decreased expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase short-chain family member 2

decreases expression

cupric chloride results in decreased expression of ACSS2 mRNA

PMID:34921933 PMID:38568856

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

actin, beta

increases expression

cupric chloride results in increased expression of ACTB protein

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actinin, alpha 1

increases expression

cupric chloride results in increased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

adenosine deaminase

decreases expression

cupric chloride results in decreased expression of ADA mRNA

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase with thrombospondin type 1 motif, 6

increases expression

cupric chloride results in increased expression of ADAMTS6 mRNA

NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298

G

adducin 3

decreases expression

cupric chloride results in decreased expression of ADD3 mRNA

NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124

G

adhesion G protein-coupled receptor G3

decreases expression

cupric chloride results in decreased expression of ADGRG3 mRNA

NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

cupric chloride results in increased expression of ADRM1 mRNA

NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195

G

adenylosuccinate synthase 1

decreases expression

cupric chloride results in decreased expression of ADSS1 mRNA

NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998

G

1-acylglycerol-3-phosphate O-acyltransferase 4

decreases expression

cupric chloride results in decreased expression of AGPAT4 mRNA

NCBI chr 1:48,525,131...48,633,798
Ensembl chr 1:48,527,323...48,633,345

G

AHNAK nucleoprotein 2

decreases expression

cupric chloride results in decreased expression of AHNAK2 mRNA

NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463

G

alpha-2-HS-glycoprotein

decreases expression

cupric chloride results in decreased expression of AHSG mRNA

NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999

G

AIF family member 2

increases expression

cupric chloride results in increased expression of AIFM2 mRNA

NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236

G

A-kinase anchoring protein 12

increases expression

cupric chloride results in increased expression of AKAP12 mRNA

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

aldo-keto reductase family 1 member A1

increases expression

cupric chloride results in increased expression of AKR1A1 protein

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1 member B1

increases expression

cupric chloride results in increased expression of AKR1B1 mRNA

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1 member B10

increases expression

cupric chloride results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

increases expression

cupric chloride results in increased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

cupric chloride results in increased expression of AKR1C2 mRNA

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

aldo-keto reductase family 1, member C3

increases expression

cupric chloride results in increased expression of AKR1C3 mRNA

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 1

increases expression

cupric chloride results in increased expression of AKT1 mRNA

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 3

increases expression

cupric chloride results in increased expression of AKT3 mRNA

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

G

5'-aminolevulinate synthase 1

increases expression

cupric chloride results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

albumin

multiple interactions

ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member L1

increases expression

cupric chloride results in increased expression of ALDH1L1 mRNA

NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465

G

aldehyde dehydrogenase 3 family, member B1

decreases expression

cupric chloride results in decreased expression of ALDH3B1 mRNA

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

aldolase, fructose-bisphosphate A

increases expression

cupric chloride results in increased expression of ALDOA mRNA

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

aldolase, fructose-bisphosphate C

decreases expression
increases expression

cupric chloride results in decreased expression of ALDOC protein
cupric chloride results in increased expression of ALDOA protein
cupric chloride results in decreased expression of ALDOC mRNA

PMID:29617964 PMID:38568856

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase

decreases activity

cupric chloride results in decreased activity of ALKBH2 protein

NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914

G

alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase

decreases activity

cupric chloride results in decreased activity of ALKBH3 protein

NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000

G

arachidonate 15-lipoxygenase, type B

decreases expression

cupric chloride results in decreased expression of ALOX15B mRNA

NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812

G

Aly/REF export factor

increases expression

cupric chloride results in increased expression of ALYREF mRNA

NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069

G

adhesion molecule with Ig like domain 2

increases expression

cupric chloride results in increased expression of AMIGO2 mRNA

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

angiomotin-like 1

increases expression

cupric chloride results in increased expression of AMOTL1 mRNA

NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573

G

angiomotin like 2

increases expression

cupric chloride results in increased expression of AMOTL2 mRNA

NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910

G

adenosine monophosphate deaminase 3

increases expression

cupric chloride results in increased expression of AMPD3 mRNA

NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887

G

angiopoietin 1

decreases expression

cupric chloride results in decreased expression of ANGPT1 mRNA

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

angiopoietin-like 4

increases expression

cupric chloride results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain 1

increases expression

cupric chloride results in increased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1

decreases expression

cupric chloride results in decreased expression of ANKZF1 mRNA

NCBI chr 9:76,688,194...76,695,162
Ensembl chr 9:76,688,194...76,696,469

G

alanyl aminopeptidase, membrane

decreases expression

cupric chloride results in decreased expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

ANTXR cell adhesion molecule 2

increases expression

cupric chloride results in increased expression of ANTXR2 mRNA

NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094

G

annexin A10

increases expression

cupric chloride results in increased expression of ANXA10 mRNA

NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648

G

annexin A5

increases expression

cupric chloride results in increased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

aldehyde oxidase 1

increases expression

cupric chloride results in increased expression of AOX1 mRNA

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

adaptor related protein complex 1 subunit mu 2

decreases expression

cupric chloride results in decreased expression of AP1M2 mRNA

NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482

G

amyloid beta precursor protein binding family B member 3

decreases expression

cupric chloride results in decreased expression of APBB3 mRNA

NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094

G

apolipoprotein M

increases expression

cupric chloride results in increased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

amyloid beta precursor protein

increases expression
multiple interactions

cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]

PMID:22542740 PMID:32512069

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 3 (Gill blood group)

decreases expression

cupric chloride results in decreased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 9

increases expression

cupric chloride results in increased expression of AQP9 mRNA

NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395

G

androgen receptor

multiple interactions

[Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

amphiregulin

increases expression

cupric chloride results in increased expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

Rho GTPase activating protein 27

increases expression

cupric chloride results in increased expression of ARHGAP27 mRNA

NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185

G

Rho GDP dissociation inhibitor alpha

increases expression

cupric chloride results in increased expression of ARHGDIA mRNA

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

Rho guanine nucleotide exchange factor 1

increases expression

cupric chloride results in increased expression of ARHGEF1 mRNA

NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953

G

Rho guanine nucleotide exchange factor 16

decreases expression

cupric chloride results in decreased expression of ARHGEF16 mRNA

NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212

G

AT-rich interaction domain 5B

decreases expression

cupric chloride results in decreased expression of ARID5B mRNA

NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433

G

ARF like GTPase 4D

decreases expression

cupric chloride results in decreased expression of ARL4D mRNA

NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836

G

armadillo repeat containing 5

increases expression

cupric chloride results in increased expression of ARMC5 mRNA

NCBI chr 1:182,820,141...182,826,913
Ensembl chr 1:182,820,141...182,826,907

G

arrestin domain containing 2

decreases expression

cupric chloride results in decreased expression of ARRDC2 mRNA

NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

increases expression

cupric chloride results in increased expression of ASAP2 mRNA

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975

G

aspartate-beta-hydroxylase

increases expression

cupric chloride results in increased expression of ASPH mRNA

NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876

G

argininosuccinate synthase 1

decreases expression

cupric chloride results in decreased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATPase family, AAA domain containing 3A

increases expression

cupric chloride results in increased expression of ATAD3A mRNA

NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482

G

activating transcription factor 2

multiple interactions

[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein]

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 4

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA]

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

ATM serine/threonine kinase

multiple interactions

cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

atonal bHLH transcription factor 8

decreases expression

cupric chloride results in decreased expression of ATOH8 mRNA

NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168

G

atos homolog A

decreases expression

cupric chloride results in decreased expression of FAM214A mRNA

NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549

G

antioxidant 1 copper chaperone

multiple interactions

[cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]

NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950

G

ATPase Na+/K+ transporting subunit beta 1

increases expression

cupric chloride results in increased expression of ATP1B1 mRNA

NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459

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ATPase copper transporting alpha

increases transport
increases expression
multiple interactions
decreases glutathionylation
affects localization

ATP7A protein results in increased transport of cupric chloride
cupric chloride results in increased expression of ATP7A protein
cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
cupric chloride results in decreased glutathionylation of ATP7A protein
cupric chloride affects the localization of ATP7A protein
Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]

PMID:11092760 PMID:16317117 PMID:17009961 PMID:20566629 PMID:21242307 More...

NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354

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ATPase copper transporting beta

decreases response to substance
affects localization
multiple interactions

ATP7B protein results in decreased susceptibility to cupric chloride
cupric chloride affects the localization of ATP7B protein
ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]

PMID:10728692 PMID:16799059 PMID:21242307 PMID:24343273 PMID:32278528

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

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ATPase phospholipid transporting 8B3

decreases expression

cupric chloride results in decreased expression of ATP8B3 mRNA

NCBI chr 7:9,175,544...9,195,449
Ensembl chr 7:9,175,391...9,195,442

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apoptosis and caspase activation inhibitor

increases expression

cupric chloride results in increased expression of AVEN mRNA

NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634

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axin 1

increases expression

cupric chloride results in increased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

increases expression

cupric chloride results in increased expression of B3GNT2 mRNA

NCBI chr14:96,808,473...96,833,674
Ensembl chr14:96,806,664...96,835,273

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beta-1,4-N-acetyl-galactosaminyl transferase 1

increases expression

cupric chloride results in increased expression of B4GALNT1 mRNA

NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190

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beta-1,4-galactosyltransferase 5

decreases expression

cupric chloride results in decreased expression of B4GALT5 mRNA

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

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beta-secretase 1

increases expression

cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein

NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876

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BAG cochaperone 1

decreases expression

cupric chloride results in decreased expression of BAG1 mRNA

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

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BAG cochaperone 3

increases expression

cupric chloride results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

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BMP and activin membrane-bound inhibitor

increases expression

cupric chloride results in increased expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

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BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

cupric chloride results in increased expression of BAX protein
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]

PMID:21035945 PMID:22239859 PMID:23313662 PMID:24170445 PMID:29803612

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

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BCL2, apoptosis regulator

multiple interactions
decreases expression

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
[Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
cupric chloride results in decreased expression of BCL2 protein

PMID:20920558 PMID:21911303 PMID:23313662 PMID:24170445

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

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Bcl2-like 1

decreases expression

cupric chloride results in decreased expression of BCL2L1 protein

PMID:23313662 PMID:24170445

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

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bradykinin receptor B2

decreases expression

cupric chloride results in decreased expression of BDKRB2 mRNA

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

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BICD cargo adaptor 2

increases expression

cupric chloride results in increased expression of BICD2 mRNA

NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889

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BH3 interacting domain death agonist

increases expression

cupric chloride results in increased expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

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biliverdin reductase B

increases expression

cupric chloride results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

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basic helix-loop-helix ARNT like 2

increases expression

cupric chloride results in increased expression of ARNTL2 mRNA

NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949

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bone morphogenetic protein 6

increases expression

cupric chloride results in increased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

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BCL2 interacting protein 3 like

decreases expression

cupric chloride results in decreased expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

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BTB domain containing 2

decreases expression

cupric chloride results in decreased expression of BTBD2 mRNA

NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344

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BTG anti-proliferation factor 1

decreases expression

cupric chloride results in decreased expression of BTG1 mRNA

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

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BTG anti-proliferation factor 2

decreases expression

cupric chloride results in decreased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

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BTG anti-proliferation factor 3

increases expression

cupric chloride results in increased expression of BTG3 mRNA

NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170

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similar to human chromosome 11 open reading frame 24

increases expression

cupric chloride results in increased expression of C11ORF24 mRNA

NCBI chr 1:200,945,188...200,953,953
Ensembl chr 1:200,945,180...200,962,585

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similar to human chromosome 11 open reading frame 86

decreases expression

cupric chloride results in decreased expression of C11ORF86 mRNA

NCBI chr 1:201,784,009...201,785,916
Ensembl chr 1:201,784,009...201,785,916

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C1q and TNF related 1

decreases expression

cupric chloride results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

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C1q and TNF related 4

increases expression

cupric chloride results in increased expression of C1QTNF4 mRNA

NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139

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complement C1r

decreases expression

cupric chloride results in decreased expression of C1R mRNA

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

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complement C1s

decreases expression

cupric chloride results in decreased expression of C1S mRNA

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

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complement C3

decreases expression

cupric chloride results in decreased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

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similar to human chromosome 20 open reading frame 96

decreases expression

cupric chloride results in decreased expression of C20ORF96 mRNA

NCBI chr 3:140,876,987...140,907,711
Ensembl chr 3:140,872,460...140,907,719

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similar to human chromosome 11 open reading frame 54

decreases expression

cupric chloride results in decreased expression of C11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

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calcium voltage-gated channel auxiliary subunit alpha2delta 3

decreases expression

cupric chloride results in decreased expression of CACNA2D3 mRNA

NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351

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cell adhesion molecule 3

decreases expression

cupric chloride results in decreased expression of CADM3 mRNA

NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749

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calbindin 1

multiple interactions

CALB1 protein inhibits the reaction [cupric chloride results in decreased activity of CTSB protein]; CALB1 protein inhibits the reaction [cupric chloride results in decreased cleavage of CTSD protein]; CALB1 protein inhibits the reaction [cupric chloride results in decreased expression of CTNS mRNA]; CALB1 protein inhibits the reaction [cupric chloride results in decreased expression of TFEB mRNA]; CALB1 protein inhibits the reaction [cupric chloride results in decreased phosphorylation of MTOR protein]; CALB1 protein inhibits the reaction [cupric chloride results in decreased phosphorylation of RPS6KB1 protein]; CALB1 protein inhibits the reaction [cupric chloride results in increased cleavage of SPTAN1 protein]; CALB1 protein inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; CALB1 protein inhibits the reaction [cupric chloride results in increased lipidation of MAP1LC3B protein]

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

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calcium binding and coiled coil domain 1

decreases expression

cupric chloride results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422

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calcium/calmodulin-dependent protein kinase II beta

decreases expression

cupric chloride results in decreased expression of CAMK2B mRNA

NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994

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calcium/calmodulin-dependent protein kinase II inhibitor 1

decreases expression

cupric chloride results in decreased expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

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carbonic anhydrase 2

decreases expression

cupric chloride results in decreased expression of CA2 mRNA

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

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carbonic anhydrase 9

decreases expression

cupric chloride results in decreased expression of CA9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

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caspase 3

multiple interactions
increases expression
increases activity
decreases activity

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
cupric chloride results in increased expression of CASP3 protein
cupric chloride results in increased activity of CASP3 protein
cupric chloride results in decreased activity of CASP3 protein

PMID:11239917 PMID:18056745 PMID:20920558 PMID:21035945 PMID:22954531 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

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caspase 7

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]

PMID:20920558 PMID:21035945

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

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caspase 8

increases expression

cupric chloride results in increased expression of CASP8 protein

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

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caspase 9

multiple interactions
increases expression

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
cupric chloride results in increased expression of CASP9 protein

PMID:20920558 PMID:23313662 PMID:24170445

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

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catalase

multiple interactions
decreases activity

Carnosine inhibits the reaction [cupric chloride results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]

PMID:29803612 PMID:32745495

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

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caveolae associated protein 1

increases expression

cupric chloride results in increased expression of CAVIN1 mRNA

NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120

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caveolae associated protein 2

decreases expression

cupric chloride results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

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Cbl proto-oncogene C

decreases expression

cupric chloride results in decreased expression of CBLC mRNA

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

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chromobox 6

increases expression

cupric chloride results in increased expression of CBX6 mRNA

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

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coiled-coil domain containing 33

decreases expression

cupric chloride results in decreased expression of CCDC33 mRNA

NCBI chr 8:58,434,798...58,534,338
Ensembl chr 8:58,435,661...58,534,370

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coiled-coil domain containing 69

decreases expression

cupric chloride results in decreased expression of CCDC69 mRNA

NCBI chr10:39,173,282...39,200,358
Ensembl chr10:39,173,282...39,199,878

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C-C motif chemokine ligand 20

increases expression

cupric chloride results in increased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

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cellular communication network factor 1

increases expression

cupric chloride results in increased expression of CCN1 mRNA

PMID:17211630 PMID:38568856

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

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cellular communication network factor 2

increases expression

cupric chloride results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

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cellular communication network factor 5

decreases expression

cupric chloride results in decreased expression of CCN5 mRNA

NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636

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cyclin D1

increases expression

cupric chloride results in increased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

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cyclin D2

decreases expression

cupric chloride results in decreased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

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cyclin E1

increases expression

cupric chloride results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

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copper chaperone for superoxide dismutase

multiple interactions

cupric chloride results in increased degradation of and results in decreased expression of CCS protein

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

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CD14 molecule

decreases expression

cupric chloride results in decreased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

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CD24 molecule

decreases expression

cupric chloride results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

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CD55 molecule (Cromer blood group)

increases expression

cupric chloride results in increased expression of CD55 mRNA

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

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Cd63 molecule

decreases expression

cupric chloride results in decreased expression of CD63 mRNA

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

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Cd70 molecule

decreases expression

cupric chloride results in decreased expression of CD70 mRNA

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

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CD83 molecule

increases expression

cupric chloride results in increased expression of CD83 mRNA

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

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CD9 molecule

decreases expression

cupric chloride results in decreased expression of CD9 mRNA

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

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codanin 1

increases expression

cupric chloride results in increased expression of CDAN1 mRNA

NCBI chr 3:107,675,147...107,689,811
Ensembl chr 3:107,673,645...107,689,773

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cell division cycle 34, ubiqiutin conjugating enzyme

affects expression

cupric chloride affects the expression of CDC34 mRNA

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

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CDC42 binding protein kinase alpha

increases expression

cupric chloride results in increased expression of CDC42BPA mRNA

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

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cell division cycle associated 4

increases expression

cupric chloride results in increased expression of CDCA4 mRNA

NCBI chr 6:131,892,305...131,901,571
Ensembl chr 6:131,892,087...131,901,564

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cadherin 1

decreases expression

cupric chloride results in decreased expression of CDH1 mRNA

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

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cadherin 3

decreases expression

cupric chloride results in decreased expression of CDH3 mRNA

NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084

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cyclin-dependent kinase 18

decreases expression

cupric chloride results in decreased expression of CDK18 mRNA

NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525

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CDK5 regulatory subunit associated protein 2

increases expression

cupric chloride results in increased expression of CDK5RAP2 mRNA

NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782

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CDK5 regulatory subunit associated protein 3

decreases expression

cupric chloride results in decreased expression of CDK5RAP3 mRNA

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

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cyclin-dependent kinase 6

increases expression

cupric chloride results in increased expression of CDK6 mRNA

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

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cyclin-dependent kinase 8

increases expression

cupric chloride results in increased expression of CDK8 mRNA

NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177

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cyclin-dependent kinase inhibitor 1A

affects expression
increases expression

cupric chloride affects the expression of CDKN1A mRNA
cupric chloride results in increased expression of CDKN1A mRNA

PMID:17211630 PMID:38568856

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

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cyclin-dependent kinase inhibitor 1B

affects expression

cupric chloride affects the expression of CDKN1B protein

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

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cyclin-dependent kinase inhibitor 1C

decreases expression

cupric chloride results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

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CCAAT/enhancer binding protein beta

increases expression

cupric chloride results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

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CCAAT/enhancer binding protein delta

decreases expression

cupric chloride results in decreased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

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carboxylesterase 1D

increases expression

cupric chloride results in increased expression of CES1 mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

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complement factor H

decreases expression

cupric chloride results in decreased expression of CFH mRNA

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

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chromatin assembly factor 1 subunit A

increases expression

cupric chloride results in increased expression of CHAF1A mRNA

NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654

G

chromodomain helicase DNA binding protein 3

decreases expression

cupric chloride results in decreased expression of CHD3 mRNA

NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047

G

cysteine and histidine rich domain containing 1

increases expression

cupric chloride results in increased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

chondroitin polymerizing factor 2

increases expression

cupric chloride results in increased expression of CHPF2 mRNA

NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916

G

cholinergic receptor nicotinic alpha 9 subunit

increases expression

cupric chloride results in increased expression of CHRNA9 mRNA

NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192

G

carbohydrate sulfotransferase 2

increases expression

cupric chloride results in increased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

class II, major histocompatibility complex, transactivator

decreases expression

cupric chloride results in decreased expression of CIITA mRNA

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

G

cytoskeleton-associated protein 4

increases expression

cupric chloride results in increased expression of CKAP4 mRNA

NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914

G

creatine kinase B

decreases expression

cupric chloride results in decreased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

creatine kinase, mitochondrial 2

decreases expression

cupric chloride results in decreased expression of CKMT2 protein

NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430

G

CDC28 protein kinase regulatory subunit 2

increases expression

cupric chloride results in increased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

chloride channel accessory 2

decreases expression

cupric chloride results in decreased expression of CLCA2 mRNA

NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199

G

cardiotrophin-like cytokine factor 1

increases expression

cupric chloride results in increased expression of CLCF1 mRNA

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

chloride voltage-gated channel 6

increases expression
decreases expression

cupric chloride results in increased expression of CLCN6 mRNA
cupric chloride results in decreased expression of CLCN6 mRNA

PMID:17211630 PMID:34921933

NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059

G

chloride voltage-gated channel 7

affects expression

cupric chloride affects the expression of CLCN7 mRNA

NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130

G

claudin 1

increases expression

cupric chloride results in increased expression of CLDN1 mRNA

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 7

decreases expression

cupric chloride results in decreased expression of CLDN7 mRNA

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

claudin domain containing 1

increases expression

cupric chloride results in increased expression of CLDND1 mRNA

NCBI chr11:41,883,120...41,889,471
Ensembl chr11:41,883,134...41,889,354

G

chloride intracellular channel 3

decreases expression

cupric chloride results in decreased expression of CLIC3 mRNA

NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018

G

CDC-like kinase 4

decreases expression

cupric chloride results in decreased expression of CLK4 mRNA

NCBI chr10:35,523,382...35,541,387
Ensembl chr10:35,524,755...35,541,352

G

CLPTM1-like

increases expression

cupric chloride results in increased expression of CLPTM1L mRNA

NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530

G

claspin

increases expression

cupric chloride results in increased expression of CLSPN mRNA

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

calsyntenin 3

decreases expression

cupric chloride results in decreased expression of CLSTN3 mRNA

NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769

G

clusterin

multiple interactions
increases expression

cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
cupric chloride results in increased expression of CLU mRNA

PMID:17211630 PMID:21242307

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

cytochrome c oxidase assembly factor 6

increases expression

cupric chloride results in increased expression of COA6 mRNA

NCBI chr19:54,395,746...54,398,348
Ensembl chr19:54,395,742...54,399,407

G

collagen type VIII alpha 1 chain

increases expression

cupric chloride results in increased expression of COL8A1 mRNA

NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424

G

copper metabolism domain containing 1

decreases response to substance
multiple interactions
decreases expression

COMMD1 protein results in decreased susceptibility to cupric chloride
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein

PMID:17211630 PMID:24691167 PMID:25007851

NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501

G

COMM domain containing 10

decreases expression

cupric chloride results in decreased expression of COMMD10 mRNA

NCBI chr18:39,741,219...39,874,801
Ensembl chr18:39,741,298...39,874,903

G

COMM domain containing 2

decreases expression

cupric chloride results in decreased expression of COMMD2 mRNA

NCBI chr 2:141,848,661...141,852,907
Ensembl chr 2:141,848,680...141,852,888

G

COMM domain containing 3

decreases expression

cupric chloride results in decreased expression of COMMD3 mRNA

NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177

G

COMM domain containing 4

decreases expression

cupric chloride results in decreased expression of COMMD4 mRNA

NCBI chr 8:57,566,236...57,569,701
Ensembl chr 8:57,566,236...57,569,760

G

COMM domain containing 5

decreases expression

cupric chloride results in decreased expression of COMMD5 mRNA

NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764

G

COMM domain containing 6

decreases expression

cupric chloride results in decreased expression of COMMD6 mRNA

NCBI chr15:78,467,333...78,474,382
Ensembl chr15:78,467,804...78,474,382

G

COMM domain containing 7

decreases expression

cupric chloride results in decreased expression of COMMD7 mRNA

NCBI chr 3:142,099,566...142,114,348
Ensembl chr 3:142,099,251...142,114,317

G

COMM domain containing 8

decreases expression

cupric chloride results in decreased expression of COMMD8 mRNA

NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617

G

COP9 signalosome subunit 8

increases expression

cupric chloride results in increased expression of COPS8 mRNA

NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258

G

cytochrome c oxidase assembly factor COX16

affects expression

cupric chloride affects the expression of COX16 mRNA

NCBI chr 6:101,162,231...101,181,277
Ensembl chr 6:101,019,680...101,181,246

G

cytochrome c oxidase subunit 5B

decreases expression

cupric chloride results in decreased expression of COX5B protein

NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052

G

cytochrome c oxidase subunit 6A1

increases expression

cupric chloride results in increased expression of COX6A1 protein

NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041

G

ceruloplasmin

increases expression

cupric chloride results in increased expression of CP mRNA

NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075

G

complexin 2

decreases expression

cupric chloride results in decreased expression of CPLX2 protein

NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855

G

copine 1

decreases expression

cupric chloride results in decreased expression of CPNE1 mRNA

NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636

G

carbamoyl-phosphate synthase 1

decreases expression

cupric chloride results in decreased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

carboxypeptidase, vitellogenic-like

decreases expression

cupric chloride results in decreased expression of CPVL mRNA

NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655

G

carnitine O-acetyltransferase

decreases expression

cupric chloride results in decreased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

CREB regulated transcription coactivator 1

decreases expression

cupric chloride results in decreased expression of CRTC1 mRNA

NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381

G

crystallin, alpha B

increases expression

cupric chloride results in increased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

colony stimulating factor 1

decreases expression

cupric chloride results in decreased expression of CSF1 mRNA

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 3

increases expression

cupric chloride results in increased expression of CSF3 mRNA

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

C-terminal Src kinase

increases expression

cupric chloride results in increased expression of CSK mRNA

NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292

G

casein kinase 1, gamma 1

decreases expression

cupric chloride results in decreased expression of CSNK1G1 mRNA

NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826

G

casein kinase 1, gamma 2

increases expression

cupric chloride results in increased expression of CSNK1G2 mRNA

NCBI chr 7:9,076,739...9,095,082
Ensembl chr 7:9,076,740...9,095,052

G

cysteine and serine rich nuclear protein 1

increases expression

cupric chloride results in increased expression of CSRNP1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cystatin B

affects binding

CSTB protein binds to cupric chloride

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

cystinosin, lysosomal cystine transporter

multiple interactions
decreases expression

CALB1 protein inhibits the reaction [cupric chloride results in decreased expression of CTNS mRNA]

NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120

G

cathepsin B

multiple interactions
increases expression
decreases activity
decreases expression

CALB1 protein inhibits the reaction [cupric chloride results in decreased activity of CTSB protein]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein]
cupric chloride results in increased expression of CTSB mRNA
cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein

PMID:32512069 PMID:37981210 PMID:38568856

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin D

decreases expression
decreases cleavage
multiple interactions

cupric chloride results in decreased expression of CTSD mRNA
cupric chloride results in decreased cleavage of CTSD protein
CALB1 protein inhibits the reaction [cupric chloride results in decreased cleavage of CTSD protein]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA]

PMID:32512069 PMID:37981210 PMID:38568856

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin H

decreases expression

cupric chloride results in decreased expression of CTSH mRNA

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cathepsin L

increases expression

cupric chloride results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cullin 4B

decreases expression

cupric chloride results in decreased expression of CUL4B mRNA

NCBI chr X:117,287,481...117,326,688
Ensembl chr X:117,287,484...117,326,688

G

CXADR, Ig-like cell adhesion molecule

decreases expression

cupric chloride results in decreased expression of CXADR mRNA

NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046

G

cytochrome b5 type A

decreases expression

cupric chloride results in decreased expression of CYB5A mRNA

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b-245 chaperone 1

increases expression

cupric chloride results in increased expression of CYBC1 mRNA

NCBI chr10:106,498,730...106,505,549
Ensembl chr10:106,498,725...106,505,596

G

cytochrome b reductase 1

decreases expression

cupric chloride results in decreased expression of CYBRD1 mRNA

NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108

G

cytochrome c, somatic

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 2

decreases expression

cupric chloride results in decreased expression of CYFIP2 mRNA

PMID:17211630 PMID:38568856

NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases stability
multiple interactions

cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein
[1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

cupric chloride results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

[CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 4, subfamily b, polypeptide 1

decreases expression

cupric chloride results in decreased expression of CYP4B1 mRNA

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 4, subfamily x, polypeptide 1

decreases expression

cupric chloride results in decreased expression of CYP4X1 mRNA

NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779

G

cytochrome P450, family 51

decreases expression

cupric chloride results in decreased expression of CYP51A1 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

differentiation antagonizing non-protein coding RNA

decreases expression

cupric chloride results in decreased expression of DANCR mRNA

NCBI chr14:34,126,956...34,127,936

G

death-associated protein kinase 2

decreases expression

cupric chloride results in decreased expression of DAPK2 mRNA

NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567

G

death-associated protein kinase 3

increases expression

cupric chloride results in increased expression of DAPK3 mRNA

NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558

G

DDB1 and CUL4 associated factor 6

decreases expression

cupric chloride results in decreased expression of DCAF6 mRNA

NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512

G

decorin

decreases expression

cupric chloride results in decreased expression of DCN mRNA

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
cupric chloride results in increased expression of DDIT3 mRNA

PMID:17211630 PMID:20920558

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

decreases expression

cupric chloride results in decreased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

discoidin domain receptor tyrosine kinase 1

decreases expression

cupric chloride results in decreased expression of DDR1 mRNA

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

G

DEAD-box helicase 54

increases expression

cupric chloride results in increased expression of DDX54 mRNA

NCBI chr12:35,934,713...35,949,956
Ensembl chr12:35,934,716...35,972,523

G

DEPP autophagy regulator 1

increases expression

cupric chloride results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

derlin 3

decreases expression

cupric chloride results in decreased expression of DERL3 mRNA

NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027

G

diacylglycerol kinase zeta

increases expression

cupric chloride results in increased expression of DGKZ mRNA

NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099

G

24-dehydrocholesterol reductase

decreases expression

cupric chloride results in decreased expression of DHCR24 mRNA

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

7-dehydrocholesterol reductase

decreases expression

cupric chloride results in decreased expression of DHCR7 mRNA

PMID:34921933 PMID:38568856

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dehydrogenase/reductase 3

decreases expression

cupric chloride results in decreased expression of DHRS3 mRNA

NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417

G

DEAH-box helicase 16

increases expression

cupric chloride results in increased expression of DHX16 mRNA

NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948

G

dickkopf WNT signaling pathway inhibitor 1

increases expression
decreases expression

cupric chloride results in increased expression of DKK1 mRNA
cupric chloride results in decreased expression of DKK1 mRNA

PMID:17211630 PMID:38568856

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

discs large MAGUK scaffold protein 5

decreases expression

cupric chloride results in decreased expression of DLG5 mRNA

NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837

G

delta like non-canonical Notch ligand 2

decreases expression

cupric chloride results in decreased expression of DLK2 mRNA

NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594

G

dystrophin

increases expression

cupric chloride results in increased expression of DMD mRNA

NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207

G

dermokine

decreases expression

cupric chloride results in decreased expression of DMKN mRNA

NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

cupric chloride results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

cupric chloride results in increased expression of DNAJB9 mRNA

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

delta/notch-like EGF repeat containing

increases expression

cupric chloride results in increased expression of DNER mRNA

NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637

G

dynamin 2

increases expression

cupric chloride results in increased expression of DNM2 mRNA

NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157

G

deoxyhypusine hydroxylase

increases expression

cupric chloride results in increased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

dihydropyrimidinase-like 2

increases expression

cupric chloride results in increased expression of DPYSL2 protein

NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829

G

dihydropyrimidinase-like 3

increases expression

cupric chloride results in increased expression of DPYSL3 mRNA

NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157

G

dihydropyrimidinase-like 5

increases expression

cupric chloride results in increased expression of DPYSL5 protein

NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422

G

Dr1 associated protein 1

increases expression

cupric chloride results in increased expression of DRAP1 mRNA

NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425

G

desmoglein 3

decreases expression

cupric chloride results in decreased expression of DSG3 mRNA

NCBI chr18:11,799,355...11,830,988
Ensembl chr18:11,798,900...11,830,818

G

desmoplakin

decreases expression

cupric chloride results in decreased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

denticleless E3 ubiquitin protein ligase homolog

increases expression

cupric chloride results in increased expression of DTL mRNA

NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890

G

dihydrouridine synthase 1-like

increases expression

cupric chloride results in increased expression of DUS1L mRNA

NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781

G

dual specificity phosphatase 1

increases expression

cupric chloride results in increased expression of DUSP1 mRNA

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 4

increases expression

cupric chloride results in increased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

dual specificity phosphatase 5

increases expression

cupric chloride results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 6

increases expression

cupric chloride results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dynein light chain LC8-type 2

increases expression

cupric chloride results in increased expression of DYNLL2 mRNA

NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805

G

E2F transcription factor 1

increases expression

cupric chloride results in increased expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

EBF transcription factor 1

decreases expression

cupric chloride results in decreased expression of EBF1 mRNA

NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665

G

EBP, cholestenol delta-isomerase

decreases expression

cupric chloride results in decreased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

enoyl-CoA hydratase 1

decreases expression

cupric chloride results in decreased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

extracellular matrix protein 1

increases expression

cupric chloride results in increased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

endothelin 2

decreases expression

cupric chloride results in decreased expression of EDN2 mRNA

NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814

G

EGF containing fibulin extracellular matrix protein 1

decreases expression

cupric chloride results in decreased expression of EFEMP1 mRNA

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

G

ephrin A1

decreases expression

cupric chloride results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

ephrin B2

increases expression

cupric chloride results in increased expression of EFNB2 mRNA

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

early growth response 1

affects expression
increases expression

cupric chloride affects the expression of EGR1 mRNA
cupric chloride results in increased expression of EGR1 mRNA

PMID:17211630 PMID:38568856

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EH domain binding protein 1-like 1

increases expression

cupric chloride results in increased expression of EHBP1L1 mRNA

NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270

G

EH-domain containing 1

increases expression

cupric chloride results in increased expression of EHD1 mRNA

NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212

G

ets homologous factor

decreases expression

cupric chloride results in decreased expression of EHF mRNA

NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997

G

elaC ribonuclease Z 2

affects expression

cupric chloride affects the expression of ELAC2 mRNA

NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614

G

E74 like ETS transcription factor 3

decreases expression

cupric chloride results in decreased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

ETS transcription factor ELK3

increases expression

cupric chloride results in increased expression of ELK3 mRNA

NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084

G

elongation factor for RNA polymerase II 2

increases expression

cupric chloride results in increased expression of ELL2 mRNA

NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781

G

ELOVL fatty acid elongase 1

increases expression

cupric chloride results in increased expression of ELOVL1 mRNA

NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958

G

ELOVL fatty acid elongase 6

decreases expression

cupric chloride results in decreased expression of ELOVL6 mRNA

PMID:34921933 PMID:38568856

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

EMAP like 4

decreases expression

cupric chloride results in decreased expression of EML4 mRNA

NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879

G

enamelin

affects expression

cupric chloride affects the expression of ENAM mRNA

NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425

G

ectodermal-neural cortex 1

increases expression

cupric chloride results in increased expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

endonuclease G

increases expression

cupric chloride results in increased expression of ENDOG protein

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

erythrocyte membrane protein band 4.1 like 4A

decreases expression

cupric chloride results in decreased expression of EPB41L4A mRNA

NCBI chr18:25,405,461...25,615,392
Ensembl chr18:25,406,057...25,615,149

G

epithelial cell adhesion molecule

decreases expression

cupric chloride results in decreased expression of EPCAM mRNA

NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127

G

epithelial mitogen

increases expression

cupric chloride results in increased expression of EPGN mRNA

NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806

G

Eph receptor B2

increases expression

cupric chloride results in increased expression of EPHB2 mRNA

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

G

Eph receptor B3

decreases expression

cupric chloride results in decreased expression of EPHB3 mRNA

NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370

G

epoxide hydrolase 1

increases expression

cupric chloride results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

Epsin 1

increases expression

cupric chloride results in increased expression of EPN1 mRNA

NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874

G

EGFR pathway substrate 8, signaling adaptor

increases expression

cupric chloride results in increased expression of EPS8 mRNA

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

EPS8-like 2

decreases expression

cupric chloride results in decreased expression of EPS8L2 mRNA

NCBI chr 1:196,446,260...196,471,544
Ensembl chr 1:196,446,287...196,471,541

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

cupric chloride results in increased expression of ERCC1 mRNA

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 6, chromatin remodeling factor

increases expression

cupric chloride results in increased expression of ERCC6 mRNA

NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587

G

epiregulin

increases expression

cupric chloride results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ergosterol biosynthesis 28 homolog

decreases expression

cupric chloride results in decreased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

estrogen receptor 1

multiple interactions
increases activity
affects response to substance
decreases expression

cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein]
cupric chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to cupric chloride
cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein

PMID:12746304 PMID:17716812

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

epithelial splicing regulatory protein 1

decreases expression

cupric chloride results in decreased expression of ESRP1 mRNA

NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062

G

ethanolamine kinase 2

decreases expression

cupric chloride results in decreased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

ETS variant transcription factor 4

increases expression

cupric chloride results in increased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

F11 receptor

decreases expression

cupric chloride results in decreased expression of F11R mRNA

NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402

G

coagulation factor II, thrombin

increases expression

cupric chloride results in increased expression of F2 mRNA

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

coagulation factor II (thrombin) receptor

decreases expression

cupric chloride results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor III, tissue factor

increases expression

cupric chloride results in increased expression of F3 mRNA

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid desaturase 2

decreases expression

cupric chloride results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

fatty acid desaturase 3

increases expression

cupric chloride results in increased expression of FADS3 mRNA

NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769

G

family with sequence similarity 110, member C

increases expression

cupric chloride results in increased expression of FAM110C mRNA

NCBI chr 6:47,638,466...47,644,723
Ensembl chr 6:47,638,276...47,644,634

G

family with sequence similarity 118, member B

increases expression

cupric chloride results in increased expression of FAM118B mRNA

NCBI chr 8:33,566,681...33,617,310
Ensembl chr 8:33,566,669...33,617,270

G

FAM20C, golgi associated secretory pathway kinase

decreases expression

cupric chloride results in decreased expression of FAM20C mRNA

NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543

G

family with sequence similarity 210, member B

decreases expression

cupric chloride results in decreased expression of FAM210B mRNA

NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397

G

family with sequence similarity 219, member A

increases expression

cupric chloride results in increased expression of FAM219A mRNA

NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924

G

family with sequence similarity 83, member G

increases expression

cupric chloride results in increased expression of FAM83G mRNA

NCBI chr10:46,363,029...46,388,030
Ensembl chr10:46,363,051...46,388,019

G

family with sequence similarity 89, member A

increases expression

cupric chloride results in increased expression of FAM89A mRNA

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

family with sequence similarity 89, member B

increases expression

cupric chloride results in increased expression of FAM89B mRNA

NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367

G

fatty acid synthase

decreases expression

cupric chloride results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 2

decreases expression

cupric chloride results in decreased expression of FAT2 mRNA

NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216

G

fibulin 1

decreases expression

cupric chloride results in decreased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

F-box protein 2

decreases expression

cupric chloride results in decreased expression of FBXO2 mRNA

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

F-box protein 32

decreases expression

cupric chloride results in decreased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 5

increases expression

cupric chloride results in increased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

Fc mu receptor

increases expression

cupric chloride results in increased expression of FCMR mRNA

NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

cupric chloride results in decreased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

cupric chloride results in decreased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

FERM domain containing kindlin 1

increases expression

cupric chloride results in increased expression of FERMT1 mRNA

NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555

G

fetuin B

increases expression

cupric chloride results in increased expression of FETUB mRNA

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

fibroblast growth factor 1

multiple interactions

[amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein]

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor 2

increases expression

cupric chloride results in increased expression of FGF2 mRNA

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor binding protein 1

decreases expression

cupric chloride results in decreased expression of FGFBP1 mRNA

NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496

G

Fibroblast growth factor receptor 1

affects expression

cupric chloride affects the expression of FGFR1 mRNA

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibrinogen-like 1

decreases expression

cupric chloride results in decreased expression of FGL1 mRNA

NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093

G

four and a half LIM domains 3

increases expression

cupric chloride results in increased expression of FHL3 mRNA

NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317

G

fin bud initiation factor homolog

decreases expression

cupric chloride results in decreased expression of FIBIN mRNA

NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676

G

FKBP prolyl isomerase 4

increases expression

cupric chloride results in increased expression of FKBP4 mRNA

NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833

G

FKBP prolyl isomerase 5

decreases expression

cupric chloride results in decreased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

Fli-1 proto-oncogene, ETS transcription factor

increases expression

cupric chloride results in increased expression of FLI1 mRNA

NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433

G

flotillin 1

decreases expression

cupric chloride results in decreased expression of FLOT1 mRNA

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

G

formin 2

increases expression

cupric chloride results in increased expression of FMN2 mRNA

NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411

G

flavin containing dimethylaniline monoxygenase 5

decreases expression

cupric chloride results in decreased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

fibronectin 1

increases expression

cupric chloride results in increased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

cupric chloride results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

increases expression

cupric chloride results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

FOS like 2, AP-1 transcription factor subunit

decreases expression

cupric chloride results in decreased expression of FOSL2 mRNA

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

G

forkhead box C2

increases expression

cupric chloride results in increased expression of FOXC2 mRNA

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

G

forkhead box O1

decreases expression

cupric chloride results in decreased expression of FOXO1 mRNA

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

forkhead box P4

increases expression

cupric chloride results in increased expression of FOXP4 mRNA

NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879

G

follistatin like 3

increases expression

cupric chloride results in increased expression of FSTL3 mRNA

NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639

G

ferritin heavy chain 1

increases expression

cupric chloride results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression

cupric chloride results in increased expression of FTL mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

far upstream element binding protein 1

increases expression

cupric chloride results in increased expression of FUBP1 protein

NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602

G

alpha-L-fucosidase 1

decreases expression

cupric chloride results in decreased expression of FUCA1 mRNA

NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972

G

furin (paired basic amino acid cleaving enzyme)

increases expression

cupric chloride results in increased expression of FURIN mRNA

NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314

G

Fus RNA binding protein

increases expression

cupric chloride results in increased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FMR1 autosomal homolog 2

increases expression

cupric chloride results in increased expression of FXR2 mRNA

NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964

G

FXYD domain-containing ion transport regulator 2

affects expression

cupric chloride affects the expression of FXYD2 mRNA

NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203

G

FYN binding protein 1

decreases expression

cupric chloride results in decreased expression of FYB1 mRNA

NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629

G

glucose-6-phosphate dehydrogenase

decreases activity
multiple interactions

cupric chloride results in decreased activity of G6PD protein
Carnosine inhibits the reaction [cupric chloride results in decreased activity of G6PD protein]

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

GABA type A receptor-associated protein

decreases expression

cupric chloride results in decreased expression of GABARAP mRNA

NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765

G

gamma-aminobutyric acid type A receptor subunit epsilon

increases expression

cupric chloride results in increased expression of GABRE mRNA

NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693

G

growth arrest and DNA-damage-inducible, alpha

increases expression

cupric chloride results in increased expression of GADD45A mRNA

PMID:17211630 PMID:38568856

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 15

decreases expression

cupric chloride results in decreased expression of GALNT15 mRNA

NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014

G

growth arrest-specific 2 like 1

increases expression

cupric chloride results in increased expression of GAS2L1 mRNA

NCBI chr14:79,955,350...79,961,830
Ensembl chr14:79,950,555...79,961,438

G

GATA zinc finger domain containing 2A

increases expression

cupric chloride results in increased expression of GATAD2A mRNA

NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587

G

guanylate binding protein 2

decreases expression

cupric chloride results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

glutamate-cysteine ligase, catalytic subunit

increases expression

cupric chloride results in increased expression of GCLC mRNA

PMID:17211630 PMID:38568856

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

cupric chloride results in increased expression of GCLM mRNA

PMID:17211630 PMID:24343273 PMID:38568856

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glucosaminyl (N-acetyl) transferase 1

increases expression

cupric chloride results in increased expression of GCNT1 mRNA

NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776

G

guanine deaminase

increases expression

cupric chloride results in increased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

GDP dissociation inhibitor 1

increases expression

cupric chloride results in increased expression of GDI1 protein

NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272

G

glutamine fructose-6-phosphate transaminase 1

increases expression

cupric chloride results in increased expression of GFPT1 mRNA

NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471

G

glutamine-fructose-6-phosphate transaminase 2

increases expression

cupric chloride results in increased expression of GFPT2 mRNA

NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329

G

gamma-glutamyltransferase 5

decreases expression

cupric chloride results in decreased expression of GGT5 mRNA

NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450

G

glycerol kinase

increases expression

cupric chloride results in increased expression of GK mRNA

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

galactosidase, alpha

increases expression

cupric chloride results in increased expression of GLA mRNA

NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664

G

glutaredoxin

increases expression

cupric chloride results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutaredoxin 2

increases expression

cupric chloride results in increased expression of GLRX2 mRNA

NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831

G

glutamate dehydrogenase 1

decreases expression

cupric chloride results in decreased expression of GLUD1 mRNA

PMID:17211630 PMID:38568856

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

ganglioside GM2 activator

decreases expression

cupric chloride results in decreased expression of GM2A mRNA

NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757

G

geminin, DNA replication inhibitor

increases expression

cupric chloride results in increased expression of GMNN mRNA

NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054

G

guanosine monophosphate reductase

decreases expression

cupric chloride results in decreased expression of GMPR mRNA

NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621

G

G protein subunit gamma 11

increases expression

cupric chloride results in increased expression of GNG11 mRNA

NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442

G

glycerol-3-phosphate acyltransferase 3

increases expression

cupric chloride results in increased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

glypican 1

increases expression

cupric chloride results in increased expression of GPC1 mRNA

NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047

G

glypican 6

decreases expression

cupric chloride results in decreased expression of GPC6 mRNA

NCBI chr15:94,030,218...95,027,883
Ensembl chr15:94,029,884...95,024,006

G

G protein-coupled receptor 4

increases expression

cupric chloride results in increased expression of GPR4 mRNA

NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599

G

G protein-coupled receptor, class C, group 5, member C

decreases expression

cupric chloride results in decreased expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

G protein-regulated inducer of neurite outgrowth 1

increases expression

cupric chloride results in increased expression of GPRIN1 mRNA

NCBI chr17:9,863,881...9,876,832
Ensembl chr17:9,863,571...9,876,915

G

GRAM domain containing 2A

decreases expression

cupric chloride results in decreased expression of GRAMD2A mRNA

NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842

G

growth regulating estrogen receptor binding 1

decreases expression

cupric chloride results in decreased expression of GREB1 mRNA

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

decreases expression

cupric chloride results in decreased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

gelsolin

increases expression

cupric chloride results in increased expression of GSN mRNA

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

glutathione-disulfide reductase

multiple interactions
decreases activity

Carnosine inhibits the reaction [cupric chloride results in decreased activity of GSR protein]

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

GTP binding protein 2

affects expression

cupric chloride affects the expression of GTPBP2 mRNA

NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241

G

GTP binding protein 6 (putative)

increases expression

cupric chloride results in increased expression of GTPBP6 mRNA

NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873

G

H1.0 linker histone

decreases expression

cupric chloride results in decreased expression of H1-0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

hyaluronan binding protein 4

increases expression

cupric chloride results in increased expression of HABP4 mRNA

NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565

G

hepcidin antimicrobial peptide

increases expression

cupric chloride results in increased expression of HAMP mRNA

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

heparin-binding EGF-like growth factor

increases expression

cupric chloride results in increased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

host cell factor C1 regulator 1

decreases expression

cupric chloride results in decreased expression of HCFC1R1 mRNA

NCBI chr10:12,705,139...12,706,852
Ensembl chr10:12,705,077...12,706,850

G

histone deacetylase 5

decreases expression

cupric chloride results in decreased expression of HDAC5 mRNA

NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235

G

HDGF like 2

increases expression

cupric chloride results in increased expression of HDGFL2 mRNA

NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186

G

hexosaminidase subunit alpha

decreases expression
multiple interactions

cupric chloride results in decreased expression of HEXA mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]

NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013

G

hepatocyte growth factor-regulated tyrosine kinase substrate

increases expression

cupric chloride results in increased expression of HGS mRNA

NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835

G

hypoxia inducible factor 1 subunit alpha

multiple interactions
increases stability
affects localization
decreases hydroxylation

Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein
cupric chloride affects the localization of HIF1A protein

PMID:15741220 PMID:19074761

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

huntingtin interacting protein 1 related

increases expression

cupric chloride results in increased expression of HIP1R mRNA

NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734

G

histone cluster 1 H2A family like 1

decreases expression

cupric chloride results in decreased expression of H2AC6 mRNA

NCBI chr17:42,707,954...42,708,420

G

histone cluster 1, H2bc

decreases expression

cupric chloride results in decreased expression of H2BC21 mRNA

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

G

Holliday junction recognition protein

increases expression

cupric chloride results in increased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

hexokinase 1

decreases activity

cupric chloride results in decreased activity of HK1 protein

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

G

hexokinase domain containing 1

increases expression

cupric chloride results in increased expression of HKDC1 mRNA

NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867

G

high mobility group AT-hook 2

increases expression

cupric chloride results in increased expression of HMGA2 mRNA

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

cupric chloride results in decreased expression of HMGCR mRNA

PMID:34921933 PMID:38568856

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

cupric chloride results in decreased expression of HMGCS1 mRNA

PMID:34921933 PMID:38568856

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

heme oxygenase 1

increases expression

cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein

PMID:17211630 PMID:21242307 PMID:24343273 PMID:38568856

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A0

increases expression

cupric chloride results in increased expression of HNRNPA0 mRNA

NCBI chr17:6,507,728...6,510,385
Ensembl chr17:6,507,275...6,509,375

G

homer scaffold protein 3

increases expression

cupric chloride results in increased expression of HOMER3 mRNA

NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680

G

hook microtubule-tethering protein 2

decreases expression

cupric chloride results in decreased expression of HOOK2 mRNA

NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181

G

homeo box A4

decreases expression

cupric chloride results in decreased expression of HOXA4 mRNA

NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:81,289,682...81,291,685

G

homeo box A5

decreases expression

cupric chloride results in decreased expression of HOXA5 mRNA

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

G

HR, lysine demethylase and nuclear receptor corepressor

decreases expression

cupric chloride results in decreased expression of HR mRNA

NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313

G

heparan sulfate-glucosamine 3-sulfotransferase 3A1

increases expression

cupric chloride results in increased expression of HS3ST3A1 mRNA

NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676

G

heparan sulfate-glucosamine 3-sulfotransferase 3B1

increases expression

cupric chloride results in increased expression of HS3ST3B1 mRNA

NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

cupric chloride results in increased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid (17-beta) dehydrogenase 1

increases expression

cupric chloride results in increased expression of HSD17B1 mRNA

NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927

G

hydroxysteroid (17-beta) dehydrogenase 2

increases expression

cupric chloride results in increased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxysteroid (17-beta) dehydrogenase 7

decreases expression

cupric chloride results in decreased expression of HSD17B7 mRNA

NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017

G

heat shock protein 90 alpha family class A member 1

increases expression

cupric chloride results in increased expression of HSP90AA1 mRNA

PMID:17211630 PMID:38568856

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 beta family member 1

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA]

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1A

affects expression

cupric chloride affects the expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

cupric chloride results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 5

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA]

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

cupric chloride results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family A (Hsp70) member 9

decreases expression

cupric chloride results in decreased expression of HSPA9 protein

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family B (small) member 1

increases expression

cupric chloride results in increased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

HIV-1 Tat interactive protein 2

increases expression

cupric chloride results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

inhibitor of DNA binding 1

decreases expression

cupric chloride results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 2

affects expression
decreases expression

cupric chloride affects the expression of ID2 mRNA
cupric chloride results in decreased expression of ID2 mRNA

PMID:17211630 PMID:38568856

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

inhibitor of DNA binding 3

decreases expression

cupric chloride results in decreased expression of ID3 mRNA

NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349

G

isocitrate dehydrogenase (NADP(+)) 1

decreases expression

cupric chloride results in decreased expression of IDH1 mRNA

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

decreases expression

cupric chloride results in decreased expression of IDH3A protein

NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

cupric chloride results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 2

increases expression

cupric chloride results in increased expression of IER2 mRNA

PMID:17211630 PMID:38568856

NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211

G

immediate early response 3

increases expression

cupric chloride results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

immediate early response 5

increases expression

cupric chloride results in increased expression of IER5 mRNA

PMID:17211630 PMID:38568856

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

interferon-induced protein 44-like

decreases expression

cupric chloride results in decreased expression of IFI44L mRNA

NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359

G

interferon induced transmembrane protein 1

decreases expression

cupric chloride results in decreased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon induced transmembrane protein 2

decreases expression

cupric chloride results in decreased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

decreases expression

cupric chloride results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

interferon gamma

multiple interactions

cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon gamma receptor 1

decreases expression

cupric chloride results in decreased expression of IFNGR1 mRNA

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

interferon-related developmental regulator 1

increases expression

cupric chloride results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

insulin-like growth factor 1

increases expression

cupric chloride results in increased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 6

decreases expression

cupric chloride results in decreased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

immunoglobulin mu DNA binding protein 2

increases expression

cupric chloride results in increased expression of IGHMBP2 mRNA

NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

increases expression

cupric chloride results in increased expression of IKBKG mRNA

PMID:17211630 PMID:38568856

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

G

interleukin 13 receptor subunit alpha 2

increases expression

cupric chloride results in increased expression of IL13RA2 mRNA

NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381

G

interleukin 1 alpha

increases secretion
increases expression

cupric chloride results in increased secretion of IL1A protein
cupric chloride results in increased expression of IL1A mRNA

PMID:22954531 PMID:38568856

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression

cupric chloride results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 1

increases expression

cupric chloride results in increased expression of IL1RL1 mRNA

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 20 receptor subunit beta

decreases expression

cupric chloride results in decreased expression of IL20RB mRNA

NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942

G

interleukin 24

increases expression

cupric chloride results in increased expression of IL24 mRNA

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

interleukin 27 receptor subunit alpha

increases expression

cupric chloride results in increased expression of IL27RA mRNA

NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938

G

interleukin 6

multiple interactions

cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inner membrane mitochondrial protein

decreases expression

cupric chloride results in decreased expression of IMMT protein

NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109

G

inosine monophosphate dehydrogenase 2

decreases expression

cupric chloride results in decreased expression of IMPDH2 mRNA

NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359

G

inhibitor of growth family, member 4

decreases expression

cupric chloride results in decreased expression of ING4 mRNA

NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265

G

inhibin subunit beta A

increases expression

cupric chloride results in increased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inositol polyphosphate-5-phosphatase D

decreases expression

cupric chloride results in decreased expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

INSC, spindle orientation adaptor protein

increases expression

cupric chloride results in increased expression of INSC mRNA

NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433

G

insulin induced gene 1

decreases expression

cupric chloride results in decreased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

inositol hexakisphosphate kinase 3

decreases expression

cupric chloride results in decreased expression of IP6K3 mRNA

NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428

G

interleukin-1 receptor-associated kinase 1

increases expression

cupric chloride results in increased expression of IRAK1 mRNA

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

G

interleukin-1 receptor-associated kinase 2

increases expression

cupric chloride results in increased expression of IRAK2 mRNA

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

G

interferon regulatory factor 2 binding protein 1

increases expression

cupric chloride results in increased expression of IRF2BP1 mRNA

NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530

G

interferon regulatory factor 6

decreases expression

cupric chloride results in decreased expression of IRF6 mRNA

NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386

G

insulin receptor substrate 2

increases expression

cupric chloride results in increased expression of IRS2 mRNA

PMID:17211630 PMID:38568856

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

iroquois homeobox 3

decreases expression

cupric chloride results in decreased expression of IRX3 mRNA

NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317

G

iroquois homeobox 4

increases expression

cupric chloride results in increased expression of IRX4 mRNA

NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549

G

isochorismatase domain containing 2b

decreases expression

cupric chloride results in decreased expression of ISOC2 mRNA

NCBI chr 1:68,972,960...68,993,760
Ensembl chr 1:68,972,960...68,993,757

G

integrin subunit alpha 2

increases expression

cupric chloride results in increased expression of ITGA2 mRNA

NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 3

increases expression

cupric chloride results in increased expression of ITGA3 mRNA

NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118

G

integrin subunit alpha 5

increases expression

cupric chloride results in increased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit beta 4

decreases expression

cupric chloride results in decreased expression of ITGB4 mRNA

NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012

G

junctional cadherin complex regulator

increases expression

cupric chloride results in increased expression of JHY mRNA

NCBI chr 8:41,276,501...41,333,383
Ensembl chr 8:41,276,491...41,333,514

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

cupric chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
[Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein

PMID:17211630 PMID:21911303 PMID:30768131 PMID:38568856

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

cupric chloride results in increased expression of JUNB mRNA

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

junction plakoglobin

decreases expression

cupric chloride results in decreased expression of JUP mRNA

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

potassium voltage-gated channel interacting protein 1

increases expression

cupric chloride results in increased expression of KCNIP1 mRNA

NCBI chr10:18,219,519...18,588,833
Ensembl chr10:18,219,519...18,589,045

G

potassium voltage-gated channel interacting protein 3

decreases expression

cupric chloride results in decreased expression of KCNIP3 mRNA

NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556

G

potassium inwardly-rectifying channel, subfamily J, member 15

increases expression

cupric chloride results in increased expression of KCNJ15 mRNA

NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952

G

lysine demethylase 2A

increases expression

cupric chloride results in increased expression of KDM2A mRNA

NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787

G

lysine demethylase 3A

increases expression

cupric chloride results in increased expression of KDM3A mRNA

NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073

G

lysine demethylase 5C

increases expression

cupric chloride results in increased expression of KDM5C mRNA

NCBI chr X:21,345,459...21,387,045
Ensembl chr X:21,345,481...21,381,870

G

kinesin family member 18B

increases expression

cupric chloride results in increased expression of KIF18B mRNA

NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850

G

kinesin family member 1C

increases expression

cupric chloride results in increased expression of KIF1C mRNA

NCBI chr10:55,414,412...55,444,587
Ensembl chr10:55,415,900...55,443,545

G

kinesin family member 5A

decreases activity
multiple interactions

cupric chloride results in decreased activity of KIF5A protein
Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]

NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858

G

kinesin light chain 2

increases expression

cupric chloride results in increased expression of KLC2 mRNA

NCBI chr 1:202,414,555...202,424,787
Ensembl chr 1:202,414,557...202,424,672

G

KLF transcription factor 16

increases expression

cupric chloride results in increased expression of KLF16 mRNA

NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317

G

KLF transcription factor 4

increases expression

cupric chloride results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 6

affects expression
increases expression

cupric chloride affects the expression of KLF6 mRNA
cupric chloride results in increased expression of KLF6 mRNA

PMID:17211630 PMID:38568856

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

kelch-like family member 21

increases expression

cupric chloride results in increased expression of KLHL21 mRNA

NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545

G

kininogen 1

increases expression

cupric chloride results in increased expression of KNG1 mRNA

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

G

kininogen 2

increases expression

cupric chloride results in increased expression of KNG2 mRNA

NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971

G

karyopherin subunit alpha 4

increases expression

cupric chloride results in increased expression of KPNA4 mRNA

NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081

G

keratin 14

increases expression
decreases expression

cupric chloride results in increased expression of KRT14 mRNA
cupric chloride results in decreased expression of KRT14 mRNA

NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799

G

keratin 15

decreases expression

cupric chloride results in decreased expression of KRT15 mRNA

NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799

G

keratin 16

increases expression

cupric chloride results in increased expression of KRT16 mRNA

NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799

G

keratin 17

increases expression

cupric chloride results in increased expression of KRT17 mRNA

NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392

G

keratin 5

increases expression

cupric chloride results in increased expression of KRT5 mRNA

NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850

G

keratin 8

decreases expression

cupric chloride results in decreased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

kynureninase

increases expression

cupric chloride results in increased expression of KYNU mRNA

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

laminin subunit alpha 3

increases expression

cupric chloride results in increased expression of LAMA3 mRNA

NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353

G

laminin subunit alpha 5

decreases expression

cupric chloride results in decreased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 3

increases expression

cupric chloride results in increased expression of LAMB3 mRNA

NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405

G

laminin subunit gamma 2

increases expression

cupric chloride results in increased expression of LAMC2 mRNA

NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200

G

lysosomal-associated membrane protein 1

decreases expression
increases expression
multiple interactions

cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein
cupric chloride results in increased expression of LAMP1 mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]

PMID:32512069 PMID:38568856

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

lysosomal-associated membrane protein 2

decreases expression
multiple interactions

cupric chloride results in decreased expression of LAMP2 mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA]

NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522

G

lysosomal protein transmembrane 5

decreases expression

cupric chloride results in decreased expression of LAPTM5 mRNA

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

G

lecithin cholesterol acyltransferase

increases expression

cupric chloride results in increased expression of LCAT mRNA

NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231

G

lipocalin 2

decreases expression

cupric chloride results in decreased expression of LCN2 mRNA

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

lymphoid enhancer binding factor 1

increases expression

cupric chloride results in increased expression of LEF1 mRNA

NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794

G

LETM1 domain containing 1

decreases expression

cupric chloride results in decreased expression of LETMD1 mRNA

NCBI chr 7:131,584,241...131,597,797
Ensembl chr 7:131,584,259...131,597,796

G

galectin 3 binding protein

decreases expression

cupric chloride results in decreased expression of LGALS3BP mRNA

NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256

G

LIF, interleukin 6 family cytokine

increases expression

cupric chloride results in increased expression of LIF mRNA

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

LIM domain kinase 1

increases expression

cupric chloride results in increased expression of LIMK1 mRNA

NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606

G

lipase A, lysosomal acid type

decreases expression

cupric chloride results in decreased expression of LIPA mRNA

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lamin A/C

increases expression

cupric chloride results in increased expression of LMNA mRNA

NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423

G

lysyl oxidase

increases activity
decreases expression
multiple interactions

cupric chloride results in increased activity of LOX protein
cupric chloride results in decreased expression of LOX mRNA
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]

PMID:22367676 PMID:25044713 PMID:38568856

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

lysyl oxidase-like 2

decreases expression

cupric chloride results in decreased expression of LOXL2 mRNA

NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067

G

lipin 1

decreases expression

cupric chloride results in decreased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

lipin 3

decreases expression

cupric chloride results in decreased expression of LPIN3 mRNA

NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327

G

LRAT domain containing 2

decreases expression

cupric chloride results in decreased expression of LRATD2 mRNA

NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189

G

leucine rich repeat and fibronectin type III domain containing 4

increases expression

cupric chloride results in increased expression of LRFN4 mRNA

NCBI chr 1:201,888,569...201,891,861
Ensembl chr 1:201,888,569...201,891,861

G

LDL receptor related protein 1

decreases expression

cupric chloride results in decreased expression of LRP1 mRNA

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

LDL receptor related protein 10

increases expression

cupric chloride results in increased expression of LRP10 mRNA

NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505

G

LDL receptor related protein 8

increases expression

cupric chloride results in increased expression of LRP8 mRNA

NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352

G

leucine rich repeat containing 59

increases expression

cupric chloride results in increased expression of LRRC59 mRNA

NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533

G

leucine-rich repeats and WD repeat domain containing 1

increases expression

cupric chloride results in increased expression of LRWD1 mRNA

NCBI chr12:20,530,035...20,543,078
Ensembl chr12:20,530,012...20,549,536

G

lanosterol synthase

decreases expression

cupric chloride results in decreased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

leukotriene A4 hydrolase

decreases expression

cupric chloride results in decreased expression of LTA4H mRNA

NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600

G

lactotransferrin

decreases expression

cupric chloride results in decreased expression of LTF mRNA

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

G

latexin

decreases expression

cupric chloride results in decreased expression of LXN mRNA

NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460

G

lymphocyte antigen 6 family member E

increases expression

cupric chloride results in increased expression of LY6E mRNA

NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689

G

lymphocyte antigen 6 family member K

increases expression

cupric chloride results in increased expression of LY6K mRNA

NCBI chr 7:106,683,749...106,712,802
Ensembl chr 7:106,683,753...106,686,372

G

Ly1 antibody reactive

increases expression

cupric chloride results in increased expression of LYAR mRNA

NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612

G

Ly6/Plaur domain containing 3

decreases expression

cupric chloride results in decreased expression of LYPD3 mRNA

NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901

G

macrophage immunometabolism regulator

increases expression

cupric chloride results in increased expression of MACIR mRNA

NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733

G

MAD2L1 binding protein

increases expression

cupric chloride results in increased expression of MAD2L1BP mRNA

NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447

G

MAF bZIP transcription factor F

increases expression

cupric chloride results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

MAF bZIP transcription factor G

increases expression

cupric chloride results in increased expression of MAFG mRNA

PMID:17211630 PMID:38568856

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

mal, T-cell differentiation protein 2

decreases expression

cupric chloride results in decreased expression of MAL2 mRNA

NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429

G

monoamine oxidase A

decreases expression

cupric chloride results in decreased expression of MAOA mRNA

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

microtubule-associated protein 1B

increases expression

cupric chloride results in increased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

microtubule-associated protein 1 light chain 3 beta

increases expression
increases lipidation
multiple interactions

cupric chloride results in increased expression of MAP1LC3B mRNA
cupric chloride results in increased lipidation of MAP1LC3B protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [cupric chloride results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; CALB1 protein inhibits the reaction [cupric chloride results in increased lipidation of MAP1LC3B protein]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]

PMID:17211630 PMID:32512069 PMID:37981210

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

microtubule-associated protein 2

increases expression

cupric chloride results in increased expression of MAP2 mRNA

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase 1

increases expression

cupric chloride results in increased expression of MAP2K1 mRNA

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 7

increases expression

cupric chloride results in increased expression of MAP2K7 mRNA

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

G

mitogen-activated protein kinase kinase kinase 11

increases expression

cupric chloride results in increased expression of MAP3K11 mRNA

NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652

G

mitogen-activated protein kinase kinase kinase 20

increases expression

cupric chloride results in increased expression of MAP3K20 mRNA

NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626

G

mitogen-activated protein kinase kinase kinase 5

decreases expression

cupric chloride results in decreased expression of MAP3K5 mRNA

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen-activated protein kinase kinase kinase kinase 4

increases expression

cupric chloride results in increased expression of MAP4K4 mRNA

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

G

MAP7 domain containing 1

increases expression

cupric chloride results in increased expression of MAP7D1 mRNA

NCBI chr 5:138,527,944...138,552,537
Ensembl chr 5:138,527,401...138,552,499

G

mitogen activated protein kinase 1

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions

[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]

PMID:11239917 PMID:20920558 PMID:30768131

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

myristoylated alanine rich protein kinase C substrate

decreases expression

cupric chloride results in decreased expression of MARCKS mRNA

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

G

methionyl-tRNA synthetase 2, mitochondrial

increases expression

cupric chloride results in increased expression of MARS2 mRNA

NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820

G

MCC regulator of WNT signaling pathway

decreases expression

cupric chloride results in decreased expression of MCC mRNA

NCBI chr18:36,794,206...37,266,237
Ensembl chr18:36,798,372...37,266,819

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

cupric chloride results in increased expression of MCL1 mRNA

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

minichromosome maintenance complex component 2

multiple interactions

cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA]

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

G

minichromosome maintenance complex component 5

multiple interactions

cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA]

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

minichromosome maintenance 8 homologous recombination repair factor

increases expression

cupric chloride results in increased expression of MCM8 mRNA

NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008

G

MyoD family inhibitor

increases expression

cupric chloride results in increased expression of MDFI mRNA

NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217

G

malate dehydrogenase 2

increases expression

cupric chloride results in increased expression of MDH2 protein

NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271

G

mediator complex subunit 15

increases expression

cupric chloride results in increased expression of MED15 mRNA

NCBI chr11:83,280,722...83,356,006
Ensembl chr11:83,280,762...83,355,362

G

multiple EGF-like-domains 6

decreases expression

cupric chloride results in decreased expression of MEGF6 mRNA

NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139

G

multiple EGF-like-domains 9

increases expression

cupric chloride results in increased expression of MEGF9 mRNA

NCBI chr 5:83,993,565...84,105,622
Ensembl chr 5:83,993,565...84,105,622

G

MET proto-oncogene, receptor tyrosine kinase

increases expression

cupric chloride results in increased expression of MET mRNA

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

methyltransferase 9, His-X-His N1(pi)-histidine

increases expression

cupric chloride results in increased expression of METTL9 mRNA

NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061

G

milk fat globule EGF and factor V/VIII domain containing

decreases expression

cupric chloride results in decreased expression of MFGE8 mRNA

NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073

G

multifunctional ROCO family signaling regulator 1

increases expression

cupric chloride results in increased expression of MFHAS1 mRNA

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

G

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

increases expression

cupric chloride results in increased expression of MGAT1 mRNA

NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503

G

monoglyceride lipase

increases expression

cupric chloride results in increased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

[Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

MID1 interacting protein 1

increases expression

cupric chloride results in increased expression of MID1IP1 mRNA

NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774

G

midnolin

increases expression

cupric chloride results in increased expression of MIDN mRNA

NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752

G

MINDY lysine 48 deubiquitinase 1

decreases expression

cupric chloride results in decreased expression of MINDY1 mRNA

NCBI chr 2:182,859,977...182,873,000
Ensembl chr 2:182,860,472...182,873,015

G

MLLT11, transcription factor 7 cofactor

increases expression

cupric chloride results in increased expression of MLLT11 mRNA

NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199

G

melanophilin

increases expression

cupric chloride results in increased expression of MLPH mRNA

NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983

G

membrane metallo-endopeptidase

decreases expression

cupric chloride results in decreased expression of MME mRNA

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 14

increases expression

cupric chloride results in increased expression of MMP14 mRNA

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 2

increases secretion

cupric chloride results in increased secretion of MMP2 protein

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 28

decreases expression

cupric chloride results in decreased expression of MMP28 mRNA

NCBI chr10:68,241,138...68,264,866
Ensembl chr10:68,241,138...68,264,866

G

motile sperm domain containing 3

decreases expression

cupric chloride results in decreased expression of MOSPD3 mRNA

NCBI chr12:19,095,203...19,100,303
Ensembl chr12:19,095,242...19,099,477

G

mannose phosphate isomerase

decreases expression

cupric chloride results in decreased expression of MPI mRNA

NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150

G

myosin phosphatase Rho interacting protein

increases expression

cupric chloride results in increased expression of MPRIP mRNA

NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118

G

mitochondrial ribosomal protein L4

increases expression

cupric chloride results in increased expression of MRPL4 mRNA

NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608

G

mesothelin

decreases expression

cupric chloride results in decreased expression of MSLN mRNA

NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643

G

methionine sulfoxide reductase B1

increases expression

cupric chloride results in increased expression of MSRB1 mRNA

NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609

G

macrophage stimulating 1 receptor

increases expression

cupric chloride results in increased expression of MST1R mRNA

NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455

G

metallothionein 1

increases expression

cupric chloride results in increased expression of MT1A mRNA

PMID:17211630 PMID:23174565

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

increases expression

cupric chloride results in increased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

multiple interactions
increases expression
affects expression

cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]
cupric chloride results in increased expression of MT2A mRNA
cupric chloride affects the expression of MT2A mRNA

PMID:17211630 PMID:17409708 PMID:19789329 PMID:20945374 PMID:23174565 More...

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metastasis associated 1

increases expression

cupric chloride results in increased expression of MTA1 mRNA

NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

increases expression

cupric chloride results in increased expression of MTHFD2L mRNA

NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112

G

mechanistic target of rapamycin kinase

increases phosphorylation
decreases phosphorylation
multiple interactions

cupric chloride results in increased phosphorylation of MTOR protein
cupric chloride results in decreased phosphorylation of MTOR protein
CALB1 protein inhibits the reaction [cupric chloride results in decreased phosphorylation of MTOR protein]

PMID:32512069 PMID:37981210

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

mucin 1, cell surface associated

decreases expression

cupric chloride results in decreased expression of MUC1 mRNA

NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733

G

mevalonate diphosphate decarboxylase

decreases expression

cupric chloride results in decreased expression of MVD mRNA

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

major vault protein

decreases expression

cupric chloride results in decreased expression of MVP mRNA

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

G

max dimerization protein 1

increases expression

cupric chloride results in increased expression of MXD1 mRNA

NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751

G

Max dimerization protein 4

decreases expression

cupric chloride results in decreased expression of MXD4 mRNA

NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221

G

MYB binding protein 1a

increases expression

cupric chloride results in increased expression of MYBBP1A mRNA

NCBI chr10:57,056,897...57,067,258
Ensembl chr10:57,056,874...57,067,255

G

myosin binding protein C1

decreases expression

cupric chloride results in decreased expression of MYBPC1 mRNA

NCBI chr 7:22,930,350...23,015,981
Ensembl chr 7:22,930,350...23,015,957

G

nucleus accumbens associated 1

increases expression

cupric chloride results in increased expression of NACC1 mRNA

NCBI chr19:23,468,688...23,486,528
Ensembl chr19:23,468,419...23,486,528

G

nicotinamide phosphoribosyltransferase

increases expression

cupric chloride results in increased expression of NAMPT mRNA

NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100

G

nuclear prelamin A recognition factor

decreases expression

cupric chloride results in decreased expression of NARF mRNA

NCBI chr10:106,519,508...106,537,494
Ensembl chr10:106,519,444...106,537,486

G

neuron navigator 3

increases expression

cupric chloride results in increased expression of NAV3 mRNA

NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698

G

NBL1, DAN family BMP antagonist

increases expression

cupric chloride results in increased expression of NBL1 mRNA

NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719

G

neutrophil cytosolic factor 2

increases expression

cupric chloride results in increased expression of NCF2 mRNA

PMID:17211630 PMID:38568856

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

G

nuclear receptor coactivator 7

decreases expression

cupric chloride results in decreased expression of NCOA7 mRNA

NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871

G

neuronal calcium sensor 1

increases expression

cupric chloride results in increased expression of NCS1 mRNA

NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829

G

NADH:ubiquinone oxidoreductase core subunit S1

decreases expression

cupric chloride results in decreased expression of NDUFS1 protein

NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893

G

NADH:ubiquinone oxidoreductase subunit S4

decreases expression

cupric chloride results in decreased expression of NDUFS4 protein

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

G

NADH:ubiquinone oxidoreductase core subunit V1

decreases expression

cupric chloride results in decreased expression of NDUFV1 protein

NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466

G

NADH:ubiquinone oxidoreductase subunit V3

decreases expression

cupric chloride results in decreased expression of NDUFV3 protein

NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

G

nectin cell adhesion molecule 4

decreases expression

cupric chloride results in decreased expression of NECTIN4 mRNA

NCBI chr13:83,802,589...83,821,711
Ensembl chr13:83,803,184...83,821,709

G

neural precursor cell expressed, developmentally down-regulated 9

increases expression

cupric chloride results in increased expression of NEDD9 mRNA

NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019

G

neurofilament light chain

decreases expression

cupric chloride results in decreased expression of NEFL protein

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

G

neuraminidase 1

decreases expression

cupric chloride results in decreased expression of NEU1 mRNA

NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745

G

neuralized E3 ubiquitin protein ligase 1B

decreases expression

cupric chloride results in decreased expression of NEURL1B mRNA

NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119

G

nuclear factor, interleukin 3 regulated

decreases expression

cupric chloride results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

nuclear factor I X

decreases expression

cupric chloride results in decreased expression of NFIX mRNA

NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265

G

nuclear factor kappa B subunit 2

increases expression

cupric chloride results in increased expression of NFKB2 mRNA

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

NFKB inhibitor alpha

decreases expression

cupric chloride results in decreased expression of NFKBIA protein

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

niban apoptosis regulator 2

increases expression

cupric chloride results in increased expression of NIBAN2 mRNA

NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293

G

nipsnap homolog 1

decreases expression

cupric chloride results in decreased expression of NIPSNAP1 mRNA

NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098

G

NME/NM23 nucleoside diphosphate kinase 1

increases expression

cupric chloride results in increased expression of NME1 protein

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

nitric oxide synthase 2

multiple interactions
increases expression

cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
cupric chloride results in increased expression of NOS2 protein

PMID:8975779 PMID:23313662 PMID:24170445 PMID:24530511

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

neuronal PAS domain protein 2

increases expression

cupric chloride results in increased expression of NPAS2 mRNA

NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320

G

natriuretic peptide receptor 3

decreases expression

cupric chloride results in decreased expression of NPR3 mRNA

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

G

NAD(P)H quinone dehydrogenase 1

increases expression

cupric chloride results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

neuronal cell adhesion molecule

increases expression

cupric chloride results in increased expression of NRCAM mRNA

NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992

G

nuclear receptor interacting protein 1

decreases expression

cupric chloride results in decreased expression of NRIP1 mRNA

NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761

G

neuropilin 2

decreases expression

cupric chloride results in decreased expression of NRP2 mRNA

NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958

G

5' nucleotidase, ecto

increases expression

cupric chloride results in increased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881

G

nucleobindin 2

increases expression

cupric chloride results in increased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

nudix hydrolase 5

increases expression

cupric chloride results in increased expression of NUDT5 mRNA

NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001

G

NUMB-like, endocytic adaptor protein

increases expression

cupric chloride results in increased expression of NUMBL mRNA

NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776

G

nucleoporin 107

increases expression

cupric chloride results in increased expression of NUP107 mRNA

NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370

G

nucleoporin 210

decreases expression

cupric chloride results in decreased expression of NUP210 mRNA

NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874

G

ornithine decarboxylase 1

increases expression

cupric chloride results in increased expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

opioid growth factor receptor

increases expression

cupric chloride results in increased expression of OGFR mRNA

NCBI chr 3:167,703,173...167,709,459
Ensembl chr 3:167,702,695...167,709,473

G

ORAI calcium release-activated calcium modulator 3

decreases expression

cupric chloride results in decreased expression of ORAI3 mRNA

NCBI chr 1:182,381,196...182,386,055
Ensembl chr 1:182,344,293...182,386,052

G

origin recognition complex, subunit 6

increases expression

cupric chloride results in increased expression of ORC6 mRNA

NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662

G

oxysterol binding protein 2

increases expression

cupric chloride results in increased expression of OSBP2 mRNA

NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786

G

oxysterol binding protein-like 6

increases expression

cupric chloride results in increased expression of OSBPL6 mRNA

NCBI chr 3:61,343,776...61,541,170
Ensembl chr 3:61,343,809...61,537,102

G

oxidative stress induced growth inhibitor 1

increases expression

cupric chloride results in increased expression of OSGIN1 mRNA

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

oxidative stress induced growth inhibitor family member 2

increases expression

cupric chloride results in increased expression of OSGIN2 mRNA

NCBI chr 5:29,500,406...29,519,340
Ensembl chr 5:29,500,408...29,520,831

G

purinergic receptor P2X 2

multiple interactions

cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]

NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891

G

prolyl 3-hydroxylase 2

decreases expression

cupric chloride results in decreased expression of P3H2 mRNA

NCBI chr11:74,634,267...74,775,422
Ensembl chr11:74,634,267...74,775,421

G

prolyl 3-hydroxylase family member 4

affects expression

cupric chloride affects the expression of P3H4 mRNA

NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093

G

proton activated chloride channel 1

increases expression

cupric chloride results in increased expression of PACC1 mRNA

NCBI chr13:102,904,668...102,929,770
Ensembl chr13:102,894,612...102,929,770

G

p21 (RAC1) activated kinase 3

decreases expression

cupric chloride results in decreased expression of PAK3 mRNA

NCBI chr X:107,116,308...107,374,342
Ensembl chr X:107,260,898...107,368,314

G

p21 (RAC1) activated kinase 6

decreases expression

cupric chloride results in decreased expression of PAK6 mRNA

NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975

G

palladin, cytoskeletal associated protein

increases expression

cupric chloride results in increased expression of PALLD mRNA

NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337

G

Pannexin 1

increases expression

cupric chloride results in increased expression of PANX1 mRNA

NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774

G

papilin, proteoglycan-like sulfated glycoprotein

decreases expression

cupric chloride results in decreased expression of PAPLN mRNA

NCBI chr 6:103,398,166...103,432,199
Ensembl chr 6:103,398,838...103,432,206

G

progestin and adipoQ receptor family member 4

increases expression

cupric chloride results in increased expression of PAQR4 mRNA

NCBI chr10:12,758,970...12,762,649
Ensembl chr10:12,758,972...12,762,584

G

progestin and adipoQ receptor family member 5

increases expression

cupric chloride results in increased expression of PAQR5 mRNA

NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688

G

progestin and adipoQ receptor family member 8

decreases expression

cupric chloride results in decreased expression of PAQR8 mRNA

NCBI chr 9:23,312,521...23,362,175
Ensembl chr 9:23,312,585...23,362,340

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases expression

[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein
cupric chloride results in increased expression of PARP1 protein

PMID:19789329 PMID:21035945 PMID:23313662

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

PBX homeobox interacting protein 1

decreases expression

cupric chloride results in decreased expression of PBXIP1 mRNA

NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919

G

pyruvate carboxylase

decreases expression

cupric chloride results in decreased expression of PC mRNA

NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380

G

protocadherin 7

increases expression

cupric chloride results in increased expression of PCDH7 mRNA

NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051

G

protocadherin 9

decreases expression

cupric chloride results in decreased expression of PCDH9 mRNA

NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538

G

pericentriolar material 1

decreases expression

cupric chloride results in decreased expression of PCM1 mRNA

NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091

G

phosphate cytidylyltransferase 2, ethanolamine

decreases expression

cupric chloride results in decreased expression of PCYT2 mRNA

NCBI chr10:105,888,769...105,896,182
Ensembl chr10:105,888,775...105,896,172

G

programmed cell death 4

decreases expression

cupric chloride results in decreased expression of PDCD4 mRNA

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

phosphodiesterase 7B

decreases expression

cupric chloride results in decreased expression of PDE7B mRNA

NCBI chr 1:15,174,001...15,493,267
Ensembl chr 1:15,182,704...15,492,900

G

protein disulfide isomerase family A, member 3

decreases expression

cupric chloride results in decreased expression of PDIA3 protein

NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236

G

pyruvate dehydrogenase kinase 2

decreases expression

cupric chloride results in decreased expression of PDK2 mRNA

NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085

G

pyruvate dehydrogenase kinase 4

decreases expression

cupric chloride results in decreased expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

PDZ and LIM domain 7

increases expression

cupric chloride results in increased expression of PDLIM7 mRNA

NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811

G

PDZ domain containing 1

decreases expression

cupric chloride results in decreased expression of PDZK1 mRNA

NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514

G

PDZK1 interacting protein 1

decreases expression

cupric chloride results in decreased expression of PDZK1IP1 mRNA

NCBI chr 5:128,618,050...128,623,131
Ensembl chr 5:128,618,237...128,623,131

G

paternally expressed 10

decreases expression

cupric chloride results in decreased expression of PEG10 mRNA

PMID:17211630 PMID:38568856

NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621

G

proline, glutamate and leucine rich protein 1

increases expression

cupric chloride results in increased expression of PELP1 mRNA