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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-(chloromethyl)pyridine
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Accession:CHEBI:76601 term browser browse the term
Definition:An organochlorine compound that is pyridine substituted at position 2 by a chloromethyl group.
Synonyms:related_synonym: 2-Chloromethylpyridine;   2-Picolyl chloride;   Formula=C6H6ClN;   InChI=1S/C6H6ClN/c7-5-6-3-1-2-4-8-6/h1-4H,5H2;   InChIKey=NJWIMFZLESWFIM-UHFFFAOYSA-N;   SMILES=ClCc1ccccn1
 xref: CAS:4377-33-7
 xref_mesh: MESH:C091423
 xref: PMID:7529357;   Reaxys:107713
 cyclic_relationship: is_conjugate_base_of CHEBI:76602


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2-(chloromethyl)pyridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm1 acyl-CoA synthetase medium-chain family member 1 increases expression ISO 2-chloromethylpyridine results in increased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 2-chloromethylpyridine results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 2-chloromethylpyridine results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO 2-chloromethylpyridine results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 2-chloromethylpyridine results in increased expression of GCLC mRNA CTD PMID:26198647 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 2-chloromethylpyridine results in increased expression of GCLM mRNA CTD PMID:26198647 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO 2-chloromethylpyridine results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO 2-chloromethylpyridine results in increased expression of GSR mRNA CTD PMID:26198647 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO 2-chloromethylpyridine results in increased activity of NFE2L2 protein CTD PMID:30114225 PMID:30203046 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 2-chloromethylpyridine results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Rras2 RAS related 2 increases expression ISO 2-chloromethylpyridine results in increased expression of RRAS2 mRNA CTD PMID:26198647 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 2-chloromethylpyridine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 2-chloromethylpyridine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2-chloromethylpyridine results in increased expression of SRXN1 mRNA CTD PMID:26198647 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        polyatomic entity 19824
          heteroatomic molecular entity 19781
            halide 18659
              organohalogen compound 18523
                organochlorine compound 18295
                  2-(chloromethyl)pyridine 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  organic heteromonocyclic compound 17791
                                    pyridines 11517
                                      2-(chloromethyl)pyridine 14
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