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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nomilin
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Accession:CHEBI:7609 term browser browse the term
Definition:A limonoid with formula C28H34O9. It is commonly found in edible citrus fruits including lemons, limes, oranges, and grapefruits. The compound exhibits a variety of biological and pharmacological activities including anticancer, antiinflammatory, antiobesity, and antiviral.
Synonyms:exact_synonym: (5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate
 related_synonym: (1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-11-(acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione;   1-(acetyloxy)-1,2-dihydro-obacunoic acid epsilon-lactone;   Formula=C28H34O9;   InChI=1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16-,17+,19+,21+,22-,25+,26-,27+,28-/m1/s1;   InChIKey=KPDOJFFZKAUIOE-WNGDLQANSA-N;   SMILES=[H][C@]12CC[C@@]3(C)[C@@H](OC(=O)[C@H]4O[C@@]34[C@]1(C)C(=O)C[C@]1([H])[C@]2(C)[C@H](CC(=O)OC1(C)C)OC(C)=O)C1=COC=C1
 xref: AGR:IND607340705;   CAS:1063-77-0;   KEGG:C08773;   KNApSAcK:C00003722
 xref_mesh: MESH:C059405
 xref: PDBeChem:G3L;   PMID:10995325;   PMID:14648393;   PMID:16719503;   PMID:21665879;   PMID:21693102;   PMID:21839074;   PMID:23374727;   PMID:25212475;   PMID:26544116;   PMID:26547535;   PMID:2710645;   PMID:27135815;   PMID:28551013;   PMID:28594916;   PMID:31093421;   PMID:31389456;   PMID:32564468;   PMID:32633501;   PMID:33991286;   PMID:35686814;   PMID:36139710;   PMID:36615463;   PMID:37076464;   PMID:37291126;   PMID:37401768;   PMID:38027676;   PMID:38088731



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nomilin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2 multiple interactions ISO nomilin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog] CTD PMID:2043152 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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  CHEBI ontology 19915
    role 19885
      chemical role 19492
        antioxidant 16172
          nomilin 1
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  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19542
                              organochalcogen compound 19302
                                organooxygen compound 19218
                                  carbon oxoacid 18664
                                    carboxylic acid 18661
                                      monocarboxylic acid 18025
                                        acetic acid 11092
                                          acetate ester 4055
                                            nomilin 1
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