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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nizatidine
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Accession:CHEBI:7601 term browser browse the term
Definition:A member of the class of 1,3-thiazoles having a dimethylaminomethyl substituent at position 2 and an alkylthiomethyl moiety at position 4.
Synonyms:exact_synonym: N-{2-[({2-[(dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine
 related_synonym: Acinon;   Axid;   Formula=C12H21N5O2S2;   InChI=1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3;   InChIKey=SGXXNSQHWDMGGP-UHFFFAOYSA-N;   N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine;   SMILES=CNC(NCCSCc1csc(CN(C)C)n1)=C[N+]([O-])=O;   nizatidina;   nizatidinum
 xref: CAS:76963-41-2;   DrugBank:DB00585;   Drug_Central:1955;   HMDB:HMDB0014723;   KEGG:C07270;   KEGG:D00440;   LINCS:LSM-3031
 xref_mesh: MESH:D016567
 xref: PMID:12520631;   PMID:20435237;   PMID:20881754;   PMID:21858296;   PMID:22374468;   PMID:22846371;   PMID:23556039;   PMID:23611167;   PMID:23836529;   PMID:24253609;   PMID:24375669;   PMID:24601855;   Reaxys:4846056;   Wikipedia:Nizatidine


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nizatidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha increases expression ISO Nizatidine results in increased expression of CALCA protein CTD PMID:12495560 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Nizatidine results in increased expression of TAC1 protein CTD PMID:12495560 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        pharmacological role 19072
          neurotransmitter agent 16793
            cholinergic drug 5361
              nizatidine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  heteroarene 17151
                                    monocyclic heteroarene 14980
                                      azole 14503
                                        thiazoles 1800
                                          1,3-thiazoles 1231
                                            nizatidine 2
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