CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: isopropyl methylphosphonofluoridate
Accession: CHEBI:75873
browse the term
Definition: A phosphinic ester that is the isopropyl ester of methylphosphonofluoridic acid.
Synonyms: exact_synonym: propan-2-yl methylphosphonofluoridate
related_synonym: Formula=C4H10FO2P; InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3; InChIKey=DYAHQFWOVKZOOW-UHFFFAOYSA-N; SMILES=CC(C)OP(C)(F)=O
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Abcb1a
ATP binding cassette subfamily B member 1A
decreases expression
ISO
Sarin results in decreased expression of ABCB1 mRNA
CTD
PMID:19522546
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcd3
ATP binding cassette subfamily D member 3
decreases expression
ISO
Sarin results in decreased expression of ABCD3 mRNA
CTD
PMID:19522546
NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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Abcf2
ATP binding cassette subfamily F member 2
decreases expression increases expression
ISO
Sarin results in decreased expression of ABCF2 mRNA Sarin results in increased expression of ABCF2 mRNA
CTD
PMID:19522546
NCBI chr 4:10,594,802...10,607,620
Ensembl chr 4:10,594,907...10,607,606
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Acaa2
acetyl-CoA acyltransferase 2
decreases expression
ISO
Sarin results in decreased expression of ACAA2 mRNA
CTD
PMID:19522546
NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression increases expression
ISO
Sarin results in decreased expression of ACAT2 mRNA Sarin results in increased expression of ACAT2 mRNA
CTD
PMID:19522546
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Ache
acetylcholinesterase
increases metabolic processing increases activity decreases expression increases phosphorylation multiple interactions decreases activity affects expression affects binding
ISO EXP
Sarin results in increased metabolism of ACHE protein; Sarin results in increased metabolism of ACHE protein mutant form Sarin results in increased activity of ACHE protein Sarin results in decreased expression of ACHE mRNA Sarin results in increased phosphorylation of ACHE protein [1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Sarin binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein 4-(ethylcarboxyl)-2'-(hydroxyiminomethyl)-1,1'-(phenylene-1,3-diyl)-bispyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; BI 6 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; naphthylene-2,7-diyl-bis(2-hydroxyiminomethylpyridinium) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Physostigmine affects the reaction [Sarin affects the expression of ACHE mRNA]; Physostigmine affects the reaction [Sarin affects the expression of and affects the activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pyridinium Compounds inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Sarin affects the expression of and affects the activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein] Sarin analog results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein 1-((4-(aminocarbonyl)pyridinio)trimethylene)-2-((hydroxyimino)methyl)pyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; 4-amino-2-((diethylamino)methyl)phenol analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with asoxime chloride] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride affects the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; benzohydroxamic acid analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Donepezil promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; HLo 7 affects the reaction [Sarin results in decreased activity of ACHE protein]; Imipramine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Imipramine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; isonitrosoacetone inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; isonitrosoacetone inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-p-xylene-bis-((2,2'-hydroxyiminomethyl)pyridinium) dibromide inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pralidoxime Compounds inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pyridine-4-aldoxime analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; RS194B analog inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS41A inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Sarin binds to and results in decreased activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein] Sarin analog results in decreased activity of ACHE protein; Sarin metabolite results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein asoxime chloride binds to [Sarin binds to ACHE protein]
CTD
PMID:1609424 PMID:12415428 PMID:14631503 PMID:16025528 PMID:17370251 PMID:17402711 PMID:17503400 PMID:18579126 PMID:18617161 PMID:19283689 PMID:19429253 PMID:19522546 PMID:19715346 PMID:20105433 PMID:20156428 PMID:20433814 PMID:20510297 PMID:20669006 PMID:20688148 PMID:20888357 PMID:21329748 PMID:21439362 PMID:21504785 PMID:21803135 PMID:21930118 PMID:22230262 PMID:22247004 PMID:22407886 PMID:22640809 PMID:22975155 PMID:22982773 PMID:23073172 PMID:23123249 PMID:23692952 PMID:25451328 PMID:25522658 PMID:25743373 PMID:25894563 PMID:26070418 PMID:27129421 PMID:27138243 PMID:27153754 PMID:28693885 PMID:28973502 PMID:29920286 PMID:30312685 PMID:30763608 PMID:31794810 PMID:31863869 PMID:33517499 PMID:33538594 More...
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Acly
ATP citrate lyase
decreases expression
ISO
Sarin results in decreased expression of ACLY mRNA
CTD
PMID:19522546
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Add1
adducin 1
decreases expression
ISO
Sarin results in decreased expression of ADD1 mRNA
CTD
PMID:19522546
NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
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Adora1
adenosine A1 receptor
increases expression
ISO
Sarin results in increased expression of ADORA1 mRNA
CTD
PMID:19522546
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Adora2a
adenosine A2a receptor
decreases expression
ISO
Sarin results in decreased expression of ADORA2A mRNA
CTD
PMID:19522546
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Agrn
agrin
decreases expression
ISO
Sarin results in decreased expression of AGRN mRNA
CTD
PMID:19522546
NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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Ahcy
adenosylhomocysteinase
decreases expression
ISO
Sarin results in decreased expression of AHCY mRNA
CTD
PMID:19522546
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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Ak1
adenylate kinase 1
decreases expression
EXP
Sarin results in decreased expression of AK1 protein
CTD
PMID:28973502
NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
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Ak3
adenylate kinase 3
decreases expression
ISO
Sarin results in decreased expression of AK3 mRNA
CTD
PMID:19522546
NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
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Akap9
A-kinase anchoring protein 9
decreases expression increases expression
ISO
Sarin results in decreased expression of AKAP9 mRNA Sarin results in increased expression of AKAP9 mRNA
CTD
PMID:19522546
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
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Alb
albumin
affects binding increases expression
ISO EXP
Sarin binds to ALB protein Sarin results in increased expression of ALB protein
CTD
PMID:17188226 PMID:28973502
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldoa
aldolase, fructose-bisphosphate A
decreases expression
ISO
Sarin results in decreased expression of ALDOA mRNA
CTD
PMID:19522546
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Aldoc
aldolase, fructose-bisphosphate C
affects expression
EXP
Sarin affects the expression of ALDOC protein
CTD
PMID:28973502
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Amacr
alpha-methylacyl-CoA racemase
decreases expression
ISO
Sarin results in decreased expression of AMACR mRNA
CTD
PMID:19522546
NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
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Apbb3
amyloid beta precursor protein binding family B member 3
increases expression
ISO
Sarin results in increased expression of APBB3 mRNA
CTD
PMID:19522546
NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
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Aplp1
amyloid beta precursor like protein 1
increases expression
ISO
Sarin results in increased expression of APLP1 mRNA
CTD
PMID:19522546
NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
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Apoa1
apolipoprotein A1
decreases expression
EXP
Sarin results in decreased expression of APOA1 protein
CTD
PMID:26778279
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Apoc4
apolipoprotein C4
increases expression
ISO
Sarin results in increased expression of APOC4 mRNA
CTD
PMID:19522546
NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
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Apoe
apolipoprotein E
increases expression
ISO EXP
Sarin results in increased expression of APOE mRNA; Sarin results in increased expression of APOE protein
CTD
PMID:16733813 PMID:19522546
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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App
amyloid beta precursor protein
decreases expression
ISO
Sarin results in decreased expression of APP mRNA
CTD
PMID:19522546
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Arpc5l
actin related protein 2/3 complex, subunit 5-like
increases expression
EXP
Sarin results in increased expression of ARPC5L protein
CTD
PMID:28973502
NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538 Ensembl chr 9:22,759,876...22,767,538
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Arrb1
arrestin, beta 1
increases expression
EXP
Sarin results in increased expression of ARRB1 mRNA
CTD
PMID:16733813
NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
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Ascl1
achaete-scute family bHLH transcription factor 1
decreases expression increases expression
ISO
Sarin results in decreased expression of ASCL1 mRNA Sarin results in increased expression of ASCL1 mRNA
CTD
PMID:19522546
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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Asic1
acid sensing ion channel subunit 1
increases expression
EXP
Sarin results in increased expression of ASIC1 mRNA
CTD
PMID:16733813
NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
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Asl
argininosuccinate lyase
decreases expression
ISO
Sarin results in decreased expression of ASL mRNA
CTD
PMID:19522546
NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
decreases expression
EXP
Sarin results in decreased expression of ATP1A1 mRNA
CTD
PMID:16733813
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
decreases expression
ISO
Sarin results in decreased expression of ATP1B1 mRNA
CTD
PMID:19522546
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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Atp1b2
ATPase Na+/K+ transporting subunit beta 2
increases expression
EXP
Sarin results in increased expression of ATP1B2 mRNA
CTD
PMID:16733813
NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
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Atp5pd
ATP synthase peripheral stalk subunit d
decreases expression
EXP
Sarin results in decreased expression of ATP5PD protein
CTD
PMID:28973502
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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Atp5po
ATP synthase peripheral stalk subunit OSCP
decreases expression
ISO
Sarin results in decreased expression of ATP5PO mRNA
CTD
PMID:19522546
NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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Atp6v0a2
ATPase H+ transporting V0 subunit a2
decreases expression
ISO
Sarin results in decreased expression of ATP6V0A2 mRNA
CTD
PMID:19522546
NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
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Atp6v0e1
ATPase H+ transporting V0 subunit e1
decreases expression
ISO
Sarin results in decreased expression of ATP6V0E mRNA
CTD
PMID:19522546
NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
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Atp9b
ATPase phospholipid transporting 9B (putative)
increases expression
ISO
Sarin results in increased expression of ATP9B mRNA
CTD
PMID:19522546
NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953
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B2m
beta-2 microglobulin
decreases expression
ISO
Sarin results in decreased expression of B2M mRNA
CTD
PMID:19522546
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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Bag1
BAG cochaperone 1
decreases expression increases expression
ISO
Sarin results in decreased expression of BAG1 mRNA Sarin results in increased expression of BAG1 mRNA
CTD
PMID:19522546
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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Bax
BCL2 associated X, apoptosis regulator
increases expression affects expression
ISO EXP
Sarin results in increased expression of BAX mRNA Sarin affects the expression of BAX mRNA; Sarin affects the expression of BAX protein
CTD
PMID:19522546 PMID:27639427
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bche
butyrylcholinesterase
multiple interactions decreases activity affects binding decreases expression increases phosphorylation decreases response to substance
ISO EXP
asoxime chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of BCHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog promotes the reaction [Sarin binds to BCHE protein] Sarin analog results in decreased activity of BCHE protein; Sarin metabolite results in decreased activity of BCHE protein; Sarin results in decreased activity of BCHE protein Sarin results in decreased expression of BCHE mRNA Sarin results in increased phosphorylation of BCHE protein BCHE protein results in decreased susceptibility to Sarin Physostigmine inhibits the reaction [Sarin results in decreased activity of BCHE protein]
CTD
PMID:17698511 PMID:18617161 PMID:19283689 PMID:19428953 PMID:19522546 PMID:19715346 PMID:19715348 PMID:21329748 PMID:21802514 PMID:22247004 PMID:22407886 PMID:26145887 PMID:26778279 PMID:29920286 PMID:30763608 PMID:31863869 PMID:33517499 More...
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl2
BCL2, apoptosis regulator
increases expression decreases expression
EXP
Sarin results in increased expression of BCL2 mRNA Sarin results in decreased expression of BCL2 protein
CTD
PMID:27639427
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression increases expression
ISO EXP
Sarin results in decreased expression of BCL2L1 mRNA Sarin results in increased expression of BCL2L1 mRNA
CTD
PMID:16733813 PMID:19522546
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Bcl2l11
Bcl2-like 11
increases expression
EXP
Sarin results in increased expression of BCL2L11 mRNA
CTD
PMID:16733813
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Bex3
brain expressed X-linked 3
decreases expression
ISO
Sarin results in decreased expression of BEX3 mRNA
CTD
PMID:19522546
NCBI chr X:99,273,270...99,274,799
Ensembl chr X:99,273,161...99,274,800
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Bptf
bromodomain PHD finger transcription factor
increases expression
ISO
Sarin results in increased expression of BPTF mRNA
CTD
PMID:19522546
NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
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Cacna1a
calcium voltage-gated channel subunit alpha1 A
decreases expression
EXP
Sarin results in decreased expression of CACNA1A mRNA
CTD
PMID:16733813
NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
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Cacng4
calcium voltage-gated channel auxiliary subunit gamma 4
decreases expression increases expression
ISO
Sarin results in decreased expression of CACNG4 mRNA Sarin results in increased expression of CACNG4 mRNA
CTD
PMID:19522546
NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
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Calcr
calcitonin receptor
increases expression
EXP
Sarin results in increased expression of CALCR mRNA
CTD
PMID:16733813
NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
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Calm1
calmodulin 1
increases expression decreases expression
ISO
Sarin results in increased expression of CALM1 mRNA Sarin results in decreased expression of CALM1 mRNA
CTD
PMID:19522546
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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Calm3
calmodulin 3
decreases expression
ISO
Sarin results in decreased expression of CALM3 mRNA
CTD
PMID:19522546
NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
decreases expression
EXP
Sarin results in decreased expression of CAMK2A mRNA
CTD
PMID:16733813
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Camk2d
calcium/calmodulin-dependent protein kinase II delta
increases expression
EXP
Sarin results in increased expression of CAMK2D mRNA
CTD
PMID:16733813
NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
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Capn1
calpain 1
increases expression
EXP
Sarin results in increased expression of CAPN1 protein
CTD
PMID:21439362
NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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Casp4
caspase 4
increases expression
ISO
Sarin results in increased expression of CASP4 mRNA
CTD
PMID:19522546
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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Casp6
caspase 6
increases expression
EXP
Sarin results in increased expression of CASP6 mRNA
CTD
PMID:16733813
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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Ccl2
C-C motif chemokine ligand 2
increases expression
EXP
Sarin results in increased expression of CCL2 mRNA
CTD
PMID:16733813
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccr1
C-C motif chemokine receptor 1
increases expression
ISO
Sarin results in increased expression of CCR1 mRNA
CTD
PMID:19522546
NCBI chr 8:123,556,286...123,561,841
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Cd24
CD24 molecule
decreases expression increases expression
ISO
Sarin results in decreased expression of CD24 mRNA Sarin results in increased expression of CD24 mRNA
CTD
PMID:19522546
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cd40lg
CD40 ligand
increases expression
EXP
Sarin results in increased expression of CD40L mRNA
CTD
PMID:16733813
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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Cd9
CD9 molecule
decreases expression
ISO
Sarin results in decreased expression of CD9 mRNA; Sarin results in decreased expression of CD9 protein
CTD
PMID:19522546
NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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Cdk5
cyclin-dependent kinase 5
decreases expression increases expression
ISO
Sarin results in decreased expression of CDK5 mRNA Sarin results in increased expression of CDK5 mRNA
CTD
PMID:19522546
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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Cept1
choline/ethanolamine phosphotransferase 1
increases expression
ISO
Sarin results in increased expression of CEPT1 mRNA
CTD
PMID:19522546
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
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Ces1d
carboxylesterase 1D
multiple interactions
ISO
CES1 protein affects the metabolism of and results in decreased activity of Sarin
CTD
PMID:12679808
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cflar
CASP8 and FADD-like apoptosis regulator
increases expression
ISO
Sarin results in increased expression of CFLAR mRNA
CTD
PMID:19522546
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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Chat
choline O-acetyltransferase
decreases expression
EXP
Sarin results in decreased expression of CHAT protein
CTD
PMID:22640809
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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Chrm2
cholinergic receptor, muscarinic 2
affects activity multiple interactions decreases expression
EXP
Sarin affects the activity of CHRM2 protein Sarin inhibits the reaction [AFDX 384 binds to CHRM2 protein] Sarin results in decreased expression of CHRM2 protein
CTD
PMID:21419149 PMID:29128314
NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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Chrna3
cholinergic receptor nicotinic alpha 3 subunit
decreases expression
ISO
Sarin results in decreased expression of CHRNA3 mRNA
CTD
PMID:19522546
NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
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Chrnb1
cholinergic receptor nicotinic beta 1 subunit
decreases expression
ISO
Sarin results in decreased expression of CHRNB1 mRNA
CTD
PMID:19522546
NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
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Chrnb4
cholinergic receptor nicotinic beta 4 subunit
decreases expression
ISO
Sarin results in decreased expression of CHRNB4 mRNA
CTD
PMID:19522546
NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
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Chrne
cholinergic receptor nicotinic epsilon subunit
increases expression
ISO
Sarin results in increased expression of CHRNE mRNA
CTD
PMID:19522546
NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
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Cklf
chemokine-like factor
decreases expression increases expression
ISO
Sarin results in decreased expression of CKLF mRNA Sarin results in increased expression of CKLF mRNA
CTD
PMID:19522546
NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570
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Clcn3
chloride voltage-gated channel 3
decreases expression
ISO
Sarin results in decreased expression of CLCN3 mRNA
CTD
PMID:19522546
NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
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Clcn5
chloride voltage-gated channel 5
increases expression
EXP
Sarin results in increased expression of CLCN5 mRNA
CTD
PMID:16733813
NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264
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Clcnkb
chloride voltage-gated channel Kb
increases expression
EXP
Sarin results in increased expression of CLCNKB mRNA
CTD
PMID:16733813
NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
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Clns1a
chloride nucleotide-sensitive channel 1A
decreases expression
ISO
Sarin results in decreased expression of CLNS1A mRNA
CTD
PMID:19522546
NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
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Clu
clusterin
decreases expression
ISO
Sarin results in decreased expression of CLU mRNA
CTD
PMID:19522546
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cnga1
cyclic nucleotide gated channel subunit alpha 1
increases expression
EXP
Sarin results in increased expression of CNGA1 mRNA
CTD
PMID:16733813
NCBI chr14:35,566,947...35,605,065
Ensembl chr14:35,567,125...35,605,065
G
Cnr2
cannabinoid receptor 2
increases expression
ISO
Sarin results in increased expression of CNR2 mRNA
CTD
PMID:19522546
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Col3a1
collagen type III alpha 1 chain
decreases expression
ISO
Sarin results in decreased expression of COL3A1 mRNA
CTD
PMID:19522546
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
G
Coro1a
coronin 1A
decreases expression
EXP
Sarin results in decreased expression of CORO1A protein
CTD
PMID:28973502
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
G
Cox15
cytochrome c oxidase assembly homolog COX15
decreases expression increases expression
ISO
Sarin results in decreased expression of COX15 mRNA Sarin results in increased expression of COX15 mRNA
CTD
PMID:19522546
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
G
Cox5a
cytochrome c oxidase subunit 5A
decreases expression
EXP
Sarin results in decreased expression of COX5A protein
CTD
PMID:28973502
NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
G
Cox5b
cytochrome c oxidase subunit 5B
decreases expression
EXP
Sarin results in decreased expression of COX5B protein
CTD
PMID:28973502
NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
G
Cox6a1
cytochrome c oxidase subunit 6A1
decreases expression increases expression
ISO EXP
Sarin results in decreased expression of COX6A1 mRNA Sarin results in increased expression of COX6A1 protein
CTD
PMID:19522546 PMID:28973502
NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
G
Cplx2
complexin 2
decreases expression
EXP
Sarin results in decreased expression of CPLX2 protein
CTD
PMID:28973502
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
G
Creb3
cAMP responsive element binding protein 3
decreases expression
ISO
Sarin results in decreased expression of CREB3 mRNA
CTD
PMID:19522546
NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
G
Cst3
cystatin C
decreases expression
ISO
Sarin results in decreased expression of CST3 mRNA
CTD
PMID:19522546
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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Cstb
cystatin B
decreases expression increases expression
ISO
Sarin results in decreased expression of CSTB mRNA Sarin results in increased expression of CSTB mRNA
CTD
PMID:19522546
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
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Ctsd
cathepsin D
decreases expression
ISO
Sarin results in decreased expression of CTSD mRNA
CTD
PMID:19522546
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
G
Cul4b
cullin 4B
decreases expression increases expression
ISO
Sarin results in decreased expression of CUL4B mRNA Sarin results in increased expression of CUL4B mRNA
CTD
PMID:19522546
NCBI chr X:117,287,481...117,326,688
Ensembl chr X:117,287,484...117,326,688
G
Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Sarin results in decreased expression of CXCR4 mRNA
CTD
PMID:19522546
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyc1
cytochrome c-1
increases expression
ISO
Sarin results in increased expression of CYC1 mRNA
CTD
PMID:19522546
NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
G
Dag1
dystroglycan 1
decreases expression
ISO
Sarin results in decreased expression of DAG1 mRNA
CTD
PMID:19522546
NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
G
Dbh
dopamine beta-hydroxylase
decreases expression
ISO
Sarin results in decreased expression of DBH mRNA
CTD
PMID:19522546
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
G
Dbn1
drebrin 1
decreases expression
ISO
Sarin results in decreased expression of DBN1 mRNA
CTD
PMID:19522546
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
G
Dctn2
dynactin subunit 2
increases expression
EXP
Sarin results in increased expression of DCTN2 protein
CTD
PMID:28973502
NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543
G
Ddah1
dimethylarginine dimethylaminohydrolase 1
affects expression
EXP
Sarin affects the expression of DDAH1 protein
CTD
PMID:28973502
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
G
Ddc
dopa decarboxylase
decreases expression affects binding
ISO
Sarin results in decreased expression of DDC mRNA; Sarin results in decreased expression of DDC protein Sarin binds to [DDC protein binds to Pyridoxal Phosphate]; Sarin binds to DDC protein
CTD
PMID:19522546 PMID:35151785
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
G
Dguok
deoxyguanosine kinase
decreases expression increases expression
ISO
Sarin results in decreased expression of DGUOK mRNA Sarin results in increased expression of DGUOK mRNA
CTD
PMID:19522546
NCBI chr 4:115,987,101...116,014,733
Ensembl chr 4:115,979,094...116,014,733
G
Dld
dihydrolipoamide dehydrogenase
decreases expression
EXP
Sarin results in decreased expression of DLD protein
CTD
PMID:28973502
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
G
Dlk1
delta like non-canonical Notch ligand 1
decreases expression
ISO
Sarin results in decreased expression of DLK1 mRNA
CTD
PMID:19522546
NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
G
Dlst
dihydrolipoamide S-succinyltransferase
decreases expression
EXP
Sarin results in decreased expression of DLST protein
CTD
PMID:28973502
NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
G
Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
decreases expression increases expression
ISO
Sarin results in decreased expression of DNAJA1 mRNA Sarin results in increased expression of DNAJA1 mRNA
CTD
PMID:19522546
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
G
Dnajb2
DnaJ heat shock protein family (Hsp40) member B2
decreases expression
ISO
Sarin results in decreased expression of DNAJB2 mRNA
CTD
PMID:19522546
NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
G
Drd5
dopamine receptor D5
increases expression
ISO
Sarin results in increased expression of DRD5 mRNA
CTD
PMID:19522546
NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
G
Dynll1
dynein light chain LC8-type 1
decreases expression increases expression
ISO
Sarin results in decreased expression of DYNLL1 mRNA Sarin results in increased expression of DYNLL1 mRNA
CTD
PMID:19522546
NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
G
Efna4
ephrin A4
decreases expression
ISO
Sarin results in decreased expression of EFNA4 mRNA
CTD
PMID:19522546
NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
G
Eid1
EP300 interacting inhibitor of differentiation 1
decreases expression increases expression
ISO
Sarin results in decreased expression of EID1 mRNA Sarin results in increased expression of EID1 mRNA
CTD
PMID:19522546
NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
G
Eif2b1
eukaryotic translation initiation factor 2B subunit alpha
decreases expression
ISO
Sarin results in decreased expression of EIF2B1 mRNA
CTD
PMID:19522546
NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
G
Elp1
elongator acetyltransferase complex subunit 1
decreases expression
ISO
Sarin results in decreased expression of ELP1 mRNA
CTD
PMID:19522546
NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
G
Eno1
enolase 1
decreases expression
EXP
Sarin results in decreased expression of ENO1 protein
CTD
PMID:28973502
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
G
Eno2
enolase 2
decreases expression
EXP
Sarin results in decreased expression of ENO2 protein
CTD
PMID:28973502
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
G
Entpd8
ectonucleoside triphosphate diphosphohydrolase 8
decreases expression
ISO
Sarin results in decreased expression of ENTPD8 mRNA
CTD
PMID:19522546
NCBI chr 3:7,885,277...7,895,517
Ensembl chr 3:7,889,909...7,895,296
G
Etfb
electron transfer flavoprotein subunit beta
decreases expression increases expression
ISO
Sarin results in decreased expression of ETFB mRNA Sarin results in increased expression of ETFB mRNA
CTD
PMID:19522546
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
G
Ets2
ETS proto-oncogene 2, transcription factor
increases expression
ISO
Sarin results in increased expression of ETS2 mRNA; Sarin results in increased expression of ETS2 protein
CTD
PMID:19522546
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
G
F12
coagulation factor XII
decreases expression
ISO
Sarin results in decreased expression of F12 mRNA
CTD
PMID:19522546
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
G
Fabp5
fatty acid binding protein 5
decreases expression
EXP
Sarin results in decreased expression of FABP5 protein
CTD
PMID:28973502
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
G
Fbln1
fibulin 1
decreases expression
ISO
Sarin results in decreased expression of FBLN1 mRNA
CTD
PMID:19522546
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
G
Fcer1a
Fc epsilon receptor Ia
increases expression
ISO
Sarin results in increased expression of FCER1A mRNA
CTD
PMID:19522546
NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
G
Fev
FEV transcription factor, ETS family member
decreases expression increases expression
ISO
Sarin results in decreased expression of FEV mRNA Sarin results in increased expression of FEV mRNA
CTD
PMID:19522546
NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065
G
Fth1
ferritin heavy chain 1
decreases expression
ISO
Sarin results in decreased expression of FTH1 mRNA
CTD
PMID:19522546
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Gabarap
GABA type A receptor-associated protein
decreases expression increases expression
ISO
Sarin results in decreased expression of GABARAP mRNA Sarin results in increased expression of GABARAP mRNA
CTD
PMID:19522546
NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
G
Gabrg3
gamma-aminobutyric acid type A receptor subunit gamma 3
increases expression
ISO
Sarin results in increased expression of GABRG3 mRNA
CTD
PMID:19522546
NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
G
Gabrr1
gamma-aminobutyric acid type A receptor subunit rho 1
decreases expression
ISO
Sarin results in decreased expression of GABRR1 mRNA
CTD
PMID:19522546
NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
G
Gabrr2
gamma-aminobutyric acid type A receptor subunit rho 2
increases expression
EXP
Sarin results in increased expression of GABRR2 mRNA
CTD
PMID:16733813
NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809
G
Gad1
glutamate decarboxylase 1
affects binding
ISO
Sarin binds to [GAD1 protein binds to Pyridoxal Phosphate]; Sarin binds to GAD1 protein
CTD
PMID:35151785
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Gad2
glutamate decarboxylase 2
affects binding
ISO
Sarin binds to [GAD2 protein binds to Pyridoxal Phosphate]; Sarin binds to GAD2 protein
CTD
PMID:35151785
NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
Sarin results in increased expression of GADD45A mRNA
CTD
PMID:19522546
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gap43
growth associated protein 43
decreases expression
ISO
Sarin results in decreased expression of GAP43 mRNA
CTD
PMID:19522546
NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
G
Gc
GC, vitamin D binding protein
increases expression
EXP
Sarin results in increased expression of GC protein
CTD
PMID:26778279
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
G
Gch1
GTP cyclohydrolase 1
decreases expression
ISO
Sarin results in decreased expression of GCH1 mRNA
CTD
PMID:19522546
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
G
Gfap
glial fibrillary acidic protein
multiple interactions increases expression
ISO EXP
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein Sarin results in increased expression of GFAP mRNA; Sarin results in increased expression of GFAP protein
CTD
PMID:16733813 PMID:23692952 PMID:27639427
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Glo1
glyoxalase 1
increases expression
EXP
Sarin results in increased expression of GLO1 protein
CTD
PMID:28973502
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
G
Glra1
glycine receptor, alpha 1
increases expression
ISO
Sarin results in increased expression of GLRA1 mRNA
CTD
PMID:19522546
NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
G
Gls
glutaminase
decreases expression
ISO
Sarin results in decreased expression of GLS mRNA
CTD
PMID:19522546
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
G
Glud1
glutamate dehydrogenase 1
decreases expression
ISO
Sarin results in decreased expression of GLUD1 mRNA
CTD
PMID:19522546
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Glul
glutamate-ammonia ligase
decreases expression increases expression
ISO EXP
Sarin results in decreased expression of GLUL mRNA Sarin results in increased expression of GLUL mRNA Sarin results in decreased expression of GLUL protein
CTD
PMID:19522546 PMID:28973502
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gnas
GNAS complex locus
decreases expression
ISO
Sarin results in decreased expression of GNAS mRNA
CTD
PMID:19522546
NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262 Ensembl chr 3:163,071,417...163,127,262
G
Gpi
glucose-6-phosphate isomerase
decreases expression
ISO
Sarin results in decreased expression of GPI mRNA
CTD
PMID:19522546
NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
G
Gpr27
G protein-coupled receptor 27
increases expression
ISO
Sarin results in increased expression of GPR27 mRNA
CTD
PMID:19522546
NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
EXP
Sarin results in decreased expression of GRIA2 mRNA
CTD
PMID:16733813
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
G
Grik5
glutamate ionotropic receptor kainate type subunit 5
increases expression
ISO
Sarin results in increased expression of GRIK5 mRNA
CTD
PMID:19522546
NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
increases expression
ISO
Sarin results in increased expression of GRIN2B mRNA
CTD
PMID:19522546
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Gsta4
glutathione S-transferase alpha 4
decreases expression
ISO
Sarin results in decreased expression of GSTA4 mRNA
CTD
PMID:19522546
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
G
Gstm5l
glutathione S-transferase, mu 5-like
increases expression
ISO
Sarin results in increased expression of GSTM5 mRNA
CTD
PMID:19522546
NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
G
Gstt2
glutathione S-transferase theta 2
decreases expression
ISO
Sarin results in decreased expression of GSTT2 mRNA
CTD
PMID:19522546
NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
G
Gstz1
glutathione S-transferase zeta 1
decreases expression
ISO
Sarin results in decreased expression of GSTZ1 mRNA
CTD
PMID:19522546
NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
G
Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
decreases expression
ISO
Sarin results in decreased expression of HADHA mRNA
CTD
PMID:19522546
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
G
Hba-a2
hemoglobin alpha, adult chain 2
decreases expression
EXP
Sarin results in decreased expression of HBA1 protein
CTD
PMID:28973502
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 Ensembl chr10:15,307,815...15,338,392
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Hdc
histidine decarboxylase
affects binding
ISO
Sarin binds to [HDC protein binds to Pyridoxal Phosphate]; Sarin binds to HDC protein
CTD
PMID:35151785
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hint1
histidine triad nucleotide binding protein 1
decreases expression
EXP
Sarin results in decreased expression of HINT1 protein
CTD
PMID:28973502
NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568
G
Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
Sarin results in increased expression of HIPK2 mRNA
CTD
PMID:19522546
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
decreases expression
EXP
Sarin results in decreased expression of HNRNPH1 protein
CTD
PMID:28973502
NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
G
Hp
haptoglobin
decreases expression
EXP
Sarin results in decreased expression of HP protein
CTD
PMID:26778279
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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Hpx
hemopexin
decreases expression
EXP
Sarin results in decreased expression of HPX protein
CTD
PMID:26778279
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
G
Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
increases expression
EXP
Sarin results in increased expression of HSD17B1 mRNA
CTD
PMID:16733813
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
G
Hspa4
heat shock protein family A (Hsp70) member 4
decreases expression increases expression
ISO
Sarin results in decreased expression of HSPA4 mRNA Sarin results in increased expression of HSPA4 mRNA
CTD
PMID:19522546
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
G
Hspa8
heat shock protein family A (Hsp70) member 8
decreases expression
EXP
Sarin results in decreased expression of HSPA8 protein
CTD
PMID:28973502
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hspa9
heat shock protein family A (Hsp70) member 9
affects expression
EXP
Sarin affects the expression of HSPA9 protein
CTD
PMID:28973502
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
decreases expression
EXP
Sarin results in decreased expression of HSPB1 mRNA
CTD
PMID:16733813
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspd1
heat shock protein family D (Hsp60) member 1
affects expression
EXP
Sarin affects the expression of HSPD1 protein
CTD
PMID:28973502
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
G
Ids
iduronate 2-sulfatase
decreases expression
ISO
Sarin results in decreased expression of IDS mRNA
CTD
PMID:19522546
NCBI chr X:149,025,976...149,046,641
Ensembl chr X:149,025,976...149,046,663
G
Ifrd1
interferon-related developmental regulator 1
decreases expression
ISO
Sarin results in decreased expression of IFRD1 mRNA
CTD
PMID:19522546
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Il10
interleukin 10
increases expression
EXP
Sarin results in increased expression of IL10 mRNA
CTD
PMID:16733813
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il17rc
interleukin 17 receptor C
increases expression
ISO
Sarin results in increased expression of IL17RC mRNA
CTD
PMID:19522546
NCBI chr 4:146,618,321...146,631,444
Ensembl chr 4:146,619,004...146,631,442
G
Il1b
interleukin 1 beta
increases expression multiple interactions
EXP ISO
Sarin results in increased expression of IL1B mRNA; Sarin results in increased expression of IL1B protein 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein ezogabine inhibits the reaction [Sarin results in increased expression of IL1B protein]
CTD
PMID:17301067 PMID:23692952 PMID:32209366
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il22ra1
interleukin 22 receptor subunit alpha 1
increases expression
ISO
Sarin results in increased expression of IL22RA1 mRNA
CTD
PMID:19522546
NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296
G
Il27ra
interleukin 27 receptor subunit alpha
increases expression
ISO
Sarin results in increased expression of IL27RA mRNA
CTD
PMID:19522546
NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938
G
Il6
interleukin 6
increases expression multiple interactions
EXP
Sarin results in increased expression of IL6 mRNA; Sarin results in increased expression of IL6 protein ezogabine inhibits the reaction [Sarin results in increased expression of IL6 protein]
CTD
PMID:17301067 PMID:32209366
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ilf2
interleukin enhancer binding factor 2
decreases expression increases expression
ISO
Sarin results in decreased expression of ILF2 mRNA Sarin results in increased expression of ILF2 mRNA
CTD
PMID:19522546
NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337
G
Ina
internexin neuronal intermediate filament protein, alpha
decreases expression
EXP
Sarin results in decreased expression of INA protein
CTD
PMID:28973502
NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
G
Insig1
insulin induced gene 1
increases expression decreases expression
ISO
Sarin results in increased expression of INSIG1 mRNA Sarin results in decreased expression of INSIG1 mRNA
CTD
PMID:19522546
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
G
Iqgap1
IQ motif containing GTPase activating protein 1
decreases expression
ISO
Sarin results in decreased expression of IQGAP1 mRNA
CTD
PMID:19522546
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
G
Irf2
interferon regulatory factor 2
decreases expression
ISO
Sarin results in decreased expression of IRF2 mRNA
CTD
PMID:19522546
NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
G
Itm2b
integral membrane protein 2B
decreases expression
ISO
Sarin results in decreased expression of ITM2B mRNA
CTD
PMID:19522546
NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
decreases expression
ISO
Sarin results in decreased expression of ITPR1 mRNA
CTD
PMID:19522546
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
G
Kat5
lysine acetyltransferase 5
decreases expression
ISO
Sarin results in decreased expression of KAT5 mRNA
CTD
PMID:19522546
NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
G
Kat6b
lysine acetyltransferase 6B
decreases expression increases expression
ISO
Sarin results in decreased expression of KAT6B mRNA Sarin results in increased expression of KAT6B mRNA
CTD
PMID:19522546
NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
G
Kcnd3
potassium voltage-gated channel subfamily D member 3
decreases expression
EXP
Sarin results in decreased expression of KCND3 mRNA
CTD
PMID:16733813
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
G
Kcnh2
potassium voltage-gated channel subfamily H member 2
increases expression
EXP
Sarin results in increased expression of KCNH2 mRNA
CTD
PMID:16733813
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
increases expression
EXP
Sarin results in increased expression of KCNJ1 mRNA
CTD
PMID:16733813
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
G
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
decreases expression increases expression
ISO
Sarin results in decreased expression of KCNJ8 mRNA Sarin results in increased expression of KCNJ8 mRNA
CTD
PMID:19522546
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
G
Kras
KRAS proto-oncogene, GTPase
decreases expression
EXP
Sarin results in decreased expression of KRAS mRNA
CTD
PMID:16733813
NCBI chr 4:178,185,418...178,218,484
G
Lamp2
lysosomal-associated membrane protein 2
decreases expression
ISO
Sarin results in decreased expression of LAMP2 mRNA
CTD
PMID:19522546
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamtor2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
decreases expression
ISO
Sarin results in decreased expression of LAMTOR2 mRNA
CTD
PMID:19522546
NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013
G
Lasp1
LIM and SH3 protein 1
decreases expression
EXP
Sarin results in decreased expression of LASP1 protein
CTD
PMID:28973502
NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
G
Lin7c
lin-7 homolog C, crumbs cell polarity complex component
increases expression
ISO
Sarin results in increased expression of LIN7C mRNA
CTD
PMID:19522546
NCBI chr 3:96,406,800...96,417,779
Ensembl chr 3:96,406,813...96,417,728
G
Litaf
lipopolysaccharide-induced TNF factor
decreases expression
ISO
Sarin results in decreased expression of LITAF mRNA
CTD
PMID:19522546
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
G
Lrp8
LDL receptor related protein 8
increases expression
ISO
Sarin results in increased expression of LRP8 mRNA
CTD
PMID:19522546
NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
G
Map2
microtubule-associated protein 2
decreases expression
EXP
Sarin results in decreased expression of MAP2 protein
CTD
PMID:27639427
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
G
Map2k2
mitogen activated protein kinase kinase 2
decreases expression
ISO
Sarin results in decreased expression of MAP2K2 mRNA
CTD
PMID:19522546
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Mapk14
mitogen activated protein kinase 14
increases expression
EXP
Sarin results in increased expression of MAPK14 mRNA
CTD
PMID:16733813
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapt
microtubule-associated protein tau
decreases expression
ISO
Sarin results in decreased expression of MAPT mRNA
CTD
PMID:19522546
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
G
Marcks
myristoylated alanine rich protein kinase C substrate
decreases expression
ISO
Sarin results in decreased expression of MARCKS mRNA
CTD
PMID:19522546
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
G
Mbp
myelin basic protein
increases expression
EXP
Sarin results in increased expression of MBP mRNA
CTD
PMID:16733813
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
G
Mcl1
MCL1 apoptosis regulator, BCL2 family member
decreases expression increases expression
ISO
Sarin results in decreased expression of MCL1 mRNA Sarin results in increased expression of MCL1 mRNA
CTD
PMID:19522546
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
G
Mfap4
microfibril associated protein 4
decreases expression increases expression
ISO
Sarin results in decreased expression of MFAP4 mRNA Sarin results in increased expression of MFAP4 mRNA
CTD
PMID:19522546
NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
G
Mfn1
mitofusin 1
decreases expression
ISO
Sarin results in decreased expression of MFN1 mRNA
CTD
PMID:19522546
NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
G
Mif
macrophage migration inhibitory factor
increases expression
EXP
Sarin results in increased expression of MIF protein
CTD
PMID:28973502
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 Ensembl chr 4:12,790,902...12,799,504
G
Mpdu1
mannose-P-dolichol utilization defect 1
decreases expression
ISO
Sarin results in decreased expression of MPDU1 mRNA
CTD
PMID:19522546
NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447
G
Mpzl1
myelin protein zero-like 1
decreases expression
ISO
Sarin results in decreased expression of MPZL1 mRNA
CTD
PMID:19522546
NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616
G
Mrps28
mitochondrial ribosomal protein S28
decreases expression
ISO
Sarin results in decreased expression of MRPS28 mRNA
CTD
PMID:19522546
NCBI chr 2:92,820,676...92,951,302
Ensembl chr 2:92,820,606...92,951,284
G
Mtmr2
myotubularin related protein 2
decreases expression
ISO
Sarin results in decreased expression of MTMR2 mRNA
CTD
PMID:19522546
NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
G
Mug2
murinoglobulin 2
increases expression
EXP
Sarin results in increased expression of PZP protein
CTD
PMID:26778279
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
G
Musk
muscle associated receptor tyrosine kinase
increases expression
ISO
Sarin results in increased expression of MUSK mRNA
CTD
PMID:19522546
NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932
G
Naca
nascent polypeptide associated complex subunit alpha
decreases expression
ISO
Sarin results in decreased expression of NACA mRNA
CTD
PMID:19522546
NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992
G
Napg
NSF attachment protein gamma
decreases expression
EXP
Sarin results in decreased expression of NAPG protein
CTD
PMID:28973502
NCBI chr18:56,439,620...56,459,159
Ensembl chr18:56,440,505...56,459,153
G
Ncor1
nuclear receptor co-repressor 1
decreases expression
ISO
Sarin results in decreased expression of NCOR1 mRNA
CTD
PMID:19522546
NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
G
Ndufs4
NADH:ubiquinone oxidoreductase subunit S4
decreases expression
ISO
Sarin results in decreased expression of NDUFS4 mRNA
CTD
PMID:19522546
NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
G
Nefh
neurofilament heavy chain
increases phosphorylation decreases expression
EXP
Sarin results in increased phosphorylation of NEFH protein Sarin results in decreased expression of NEFH mRNA
CTD
PMID:16733813 PMID:21439362
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
G
Nfkb1
nuclear factor kappa B subunit 1
affects localization
EXP
Sarin affects the localization of NFKB1 protein
CTD
PMID:17301067
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nfyc
nuclear transcription factor Y subunit gamma
decreases expression
EXP
Sarin results in decreased expression of NFYC mRNA
CTD
PMID:16733813
NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377
G
Ngrn
neugrin, neurite outgrowth associated
decreases expression
ISO
Sarin results in decreased expression of NGRN mRNA
CTD
PMID:19522546
NCBI chr 1:134,213,235...134,219,348
Ensembl chr 1:134,213,456...134,219,339
G
Nme1
NME/NM23 nucleoside diphosphate kinase 1
decreases expression
EXP
Sarin results in decreased expression of NME1 protein
CTD
PMID:28973502
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Sarin affects the expression of NME2 protein
CTD
PMID:28973502
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 Ensembl chr20:78,897,770...78,903,538
G
Nmu
neuromedin U
decreases expression
ISO
Sarin results in decreased expression of NMU mRNA
CTD
PMID:19522546
NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
G
Nosip
nitric oxide synthase interacting protein
increases expression
ISO
Sarin results in increased expression of NOSIP mRNA
CTD
PMID:19522546
NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650
G
Notch2
notch receptor 2
decreases expression
ISO
Sarin results in decreased expression of NOTCH2 mRNA
CTD
PMID:19522546
NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
G
Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression
ISO
Sarin results in decreased expression of NQO1 mRNA
CTD
PMID:19522546
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
decreases expression
ISO
Sarin results in decreased expression of NQO2 mRNA
CTD
PMID:19522546
NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
G
Nrcam
neuronal cell adhesion molecule
decreases expression
ISO
Sarin results in decreased expression of NRCAM mRNA
CTD
PMID:19522546
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
G
Nrp1
neuropilin 1
decreases expression increases expression
ISO
Sarin results in decreased expression of NRP1 mRNA Sarin results in increased expression of NRP1 mRNA
CTD
PMID:19522546
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
increases expression
ISO
Sarin results in increased expression of NTRK2 mRNA
CTD
PMID:19522546
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
G
Ntrk3
neurotrophic receptor tyrosine kinase 3
increases expression
ISO
Sarin results in increased expression of NTRK3 mRNA
CTD
PMID:19522546
NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
G
Olr1
oxidized low density lipoprotein receptor 1
decreases expression increases expression
ISO
Sarin results in decreased expression of OLR1 mRNA Sarin results in increased expression of OLR1 mRNA
CTD
PMID:19522546
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
G
Or10al6
olfactory receptor family 10 subfamily AL member 6
increases expression
EXP
Sarin results in increased expression of OR10AL6 mRNA
CTD
PMID:16733813
NCBI chr20:738,257...739,607
Ensembl chr20:734,965...811,125
G
Osmr
oncostatin M receptor
increases expression
ISO
Sarin results in increased expression of OSMR mRNA
CTD
PMID:19522546
NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
G
P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
Sarin results in decreased expression of P4HB mRNA
CTD
PMID:19522546
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Pank3
pantothenate kinase 3
decreases expression
ISO
Sarin results in decreased expression of PANK3 mRNA
CTD
PMID:19522546
NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
G
Park7
Parkinsonism associated deglycase
decreases expression
ISO EXP
Sarin results in decreased expression of PARK7 mRNA Sarin results in decreased expression of PARK7 protein
CTD
PMID:19522546 PMID:28973502
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
G
Parl
presenilin associated, rhomboid-like
decreases expression
ISO
Sarin results in decreased expression of PARL mRNA
CTD
PMID:19522546
NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
G
Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
decreases expression
ISO
Sarin results in decreased expression of PCMT1 mRNA
CTD
PMID:19522546
NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
G
Pdhb
pyruvate dehydrogenase E1 subunit beta
decreases expression increases expression
ISO EXP
Sarin results in decreased expression of PDHB mRNA Sarin results in increased expression of PDHB mRNA Sarin results in decreased expression of PDHB protein
CTD
PMID:19522546 PMID:28973502
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
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Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Sarin affects the expression of PDIA3 protein
CTD
PMID:28973502
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pemt
phosphatidylethanolamine N-methyltransferase
decreases expression
ISO
Sarin results in decreased expression of PEMT mRNA
CTD
PMID:19522546
NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
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Pepd
peptidase D
increases hydrolysis
ISO
PEPD protein results in increased hydrolysis of Sarin
CTD
PMID:20176006 PMID:22120822 PMID:22677456
NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231
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Pfkp
phosphofructokinase, platelet
decreases expression
ISO
Sarin results in decreased expression of PFKP mRNA
CTD
PMID:19522546
NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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Pfn2
profilin 2
decreases expression
EXP
Sarin results in decreased expression of PFN2 protein
CTD
PMID:28973502
NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
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Pla2g5
phospholipase A2, group V
decreases expression increases expression
ISO
Sarin results in decreased expression of PLA2G5 mRNA Sarin results in increased expression of PLA2G5 mRNA
CTD
PMID:19522546
NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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Pla2g6
phospholipase A2 group VI
increases expression
ISO
Sarin results in increased expression of PLA2G6 mRNA
CTD
PMID:19522546
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
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Plaa
phospholipase A2, activating protein
increases expression
ISO
Sarin results in increased expression of PLAA mRNA
CTD
PMID:19522546
NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
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Plp1
proteolipid protein 1
increases expression
EXP
Sarin results in increased expression of PLP1 mRNA
CTD
PMID:16733813
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
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Pltp
phospholipid transfer protein
decreases expression
ISO
Sarin results in decreased expression of PLTP mRNA
CTD
PMID:19522546
NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
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Pmp22
peripheral myelin protein 22
decreases expression
ISO
Sarin results in decreased expression of PMP22 mRNA
CTD
PMID:19522546
NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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Pnma1
PNMA family member 1
decreases expression increases expression
ISO
Sarin results in decreased expression of PNMA1 mRNA Sarin results in increased expression of PNMA1 mRNA
CTD
PMID:19522546
NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567
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Pnpla6
patatin-like phospholipase domain containing 6
decreases activity
ISO
Sarin results in decreased activity of PNPLA6 protein
CTD
PMID:8486913
NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
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Pomc
proopiomelanocortin
decreases expression
EXP
Sarin results in decreased expression of POMC protein
CTD
PMID:17301067
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Pon1
paraoxonase 1
multiple interactions decreases response to substance increases hydrolysis
ISO
PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein] PON1 protein mutant form results in decreased susceptibility to Sarin PON1 protein mutant form results in increased hydrolysis of Sarin; PON1 protein results in increased hydrolysis of Sarin
CTD
PMID:16331452 PMID:20176006 PMID:21329748 PMID:23159884
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Por
cytochrome p450 oxidoreductase
decreases expression increases expression
ISO
Sarin results in decreased expression of POR mRNA Sarin results in increased expression of POR mRNA
CTD
PMID:19522546
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Ppp1ca
protein phosphatase 1 catalytic subunit alpha
decreases expression
ISO
Sarin results in decreased expression of PPP1CA mRNA
CTD
PMID:19522546
NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
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Ppt1
palmitoyl-protein thioesterase 1
decreases expression
ISO
Sarin results in decreased expression of PPT1 mRNA
CTD
PMID:19522546
NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
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Prdx6
peroxiredoxin 6
decreases expression
EXP
Sarin results in decreased expression of PRDX6 protein
CTD
PMID:28973502
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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Prkcb
protein kinase C, beta
increases expression
ISO
Sarin results in increased expression of PRKCB mRNA
CTD
PMID:19522546
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prss12
serine protease 12
decreases expression
ISO
Sarin results in decreased expression of PRSS12 mRNA
CTD
PMID:19522546
NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126
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Psen1
presenilin 1
decreases expression
ISO
Sarin results in decreased expression of PSEN1 mRNA; Sarin results in decreased expression of PSEN1 protein
CTD
PMID:19522546
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Psen2
presenilin 2
decreases expression
ISO
Sarin results in decreased expression of PSEN2 mRNA
CTD
PMID:19522546
NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
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Psma1
proteasome 20S subunit alpha 1
increases expression
EXP
Sarin results in increased expression of PSMA1 protein
CTD
PMID:28973502
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
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Psma3
proteasome 20S subunit alpha 3
decreases expression increases expression
ISO
Sarin results in decreased expression of PSMA3 mRNA Sarin results in increased expression of PSMA3 mRNA
CTD
PMID:19522546
NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
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Psmd8
proteasome 26S subunit, non-ATPase 8
decreases expression
ISO
Sarin results in decreased expression of PSMD8 mRNA
CTD
PMID:19522546
NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
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Ptger3
prostaglandin E receptor 3
decreases expression
EXP
Sarin results in decreased expression of PTGER3 mRNA
CTD
PMID:16733813
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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Ptprr
protein tyrosine phosphatase, receptor type, R
decreases expression
ISO
Sarin results in decreased expression of PTPRR mRNA
CTD
PMID:19522546
NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
G
Pts
6-pyruvoyl-tetrahydropterin synthase
decreases expression
ISO
Sarin results in decreased expression of PTS mRNA
CTD
PMID:19522546
NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869
G
Pura
purine rich element binding protein A
affects expression
EXP
Sarin affects the expression of PURA protein
CTD
PMID:28973502
NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513
G
Ranbp1
RAN binding protein 1
decreases expression
ISO
Sarin results in decreased expression of RANBP1 mRNA
CTD
PMID:19522546
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
G
Rasgrp2
RAS guanyl releasing protein 2
increases expression
ISO
Sarin results in increased expression of RASGRP2 mRNA
CTD
PMID:19522546
NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993
G
Rfxank
regulatory factor X-associated ankyrin-containing protein
decreases expression
ISO
Sarin results in decreased expression of RFXANK mRNA
CTD
PMID:19522546
NCBI chr16:19,280,857...19,288,886
Ensembl chr16:19,281,475...19,460,255
G
Rgn
regucalcin
increases hydrolysis
ISO
RGN protein results in increased hydrolysis of Sarin
CTD
PMID:20176006
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Rgs4
regulator of G-protein signaling 4
decreases expression
ISO
Sarin results in decreased expression of RGS4 mRNA
CTD
PMID:19522546
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
G
Rtn3
reticulon 3
decreases expression
ISO
Sarin results in decreased expression of RTN3 mRNA
CTD
PMID:19522546
NCBI chr 1:204,612,675...204,669,212
Ensembl chr 1:204,612,675...204,669,275
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S100b
S100 calcium binding protein B
increases expression
EXP
Sarin results in increased expression of S100B mRNA
CTD
PMID:16733813
NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
G
Scarb2
scavenger receptor class B, member 2
decreases expression
ISO
Sarin results in decreased expression of SCARB2 mRNA
CTD
PMID:19522546
NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
G
Scd
stearoyl-CoA desaturase
decreases expression increases expression
ISO
Sarin results in decreased expression of SCD mRNA Sarin results in increased expression of SCD mRNA
CTD
PMID:19522546
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn10a
sodium voltage-gated channel alpha subunit 10
increases expression
ISO
Sarin results in increased expression of SCN10A mRNA
CTD
PMID:19522546
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
G
Scn2b
sodium voltage-gated channel beta subunit 2
increases expression
EXP
Sarin results in increased expression of SCN2B mRNA
CTD
PMID:16733813
NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765
G
Sdcbp
syndecan binding protein
decreases expression
ISO
Sarin results in decreased expression of SDCBP mRNA
CTD
PMID:19522546
NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
G
Septin5
septin 5
increases expression
EXP
Sarin results in increased expression of SEPTIN5 protein
CTD
PMID:28973502
NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393
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Serpini1
serpin family I member 1
decreases expression
ISO
Sarin results in decreased expression of SERPINI1 mRNA
CTD
PMID:19522546
NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
G
Sgk1
serum/glucocorticoid regulated kinase 1
decreases expression
ISO
Sarin results in decreased expression of SGK1 mRNA
CTD
PMID:19522546
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
G
Sh3gl1
SH3 domain containing GRB2 like 1, endophilin A2
decreases expression
EXP
Sarin results in decreased expression of SH3GL1 protein
CTD
PMID:28973502
NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
G
Slc18a3
solute carrier family 18 member A3
decreases expression
EXP
Sarin results in decreased expression of SLC18A3 protein
CTD
PMID:22640809
NCBI chr16:7,713,630...7,716,491
G
Slc20a1
solute carrier family 20 member 1
decreases expression
ISO
Sarin results in decreased expression of SLC20A1 mRNA
CTD
PMID:19522546
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
G
Slc6a15
solute carrier family 6 member 15
decreases expression
ISO
Sarin results in decreased expression of SLC6A15 mRNA
CTD
PMID:19522546
NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
G
Snca
synuclein alpha
decreases expression
ISO EXP
Sarin results in decreased expression of SNCA mRNA Sarin results in decreased expression of SNCA protein
CTD
PMID:19522546 PMID:28973502
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
G
Socs3
suppressor of cytokine signaling 3
increases expression
EXP
Sarin results in increased expression of SOCS3 mRNA
CTD
PMID:16733813
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
G
Socs5
suppressor of cytokine signaling 5
decreases expression increases expression
ISO
Sarin results in decreased expression of SOCS5 mRNA Sarin results in increased expression of SOCS5 mRNA
CTD
PMID:19522546
NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
G
Sod1
superoxide dismutase 1
decreases expression
EXP
Sarin results in decreased expression of SOD1 protein
CTD
PMID:28973502
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Spast
spastin
decreases expression
ISO
Sarin results in decreased expression of SPG4 mRNA
CTD
PMID:19522546
NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
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Stip1
stress-induced phosphoprotein 1
affects expression
EXP
Sarin affects the expression of STIP1 protein
CTD
PMID:28973502
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
G
Stmn1
stathmin 1
decreases expression
EXP
Sarin results in decreased expression of STMN1 protein
CTD
PMID:28973502
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
G
Stmn2
stathmin 2
decreases expression
ISO
Sarin results in decreased expression of STMN2 mRNA
CTD
PMID:19522546
NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
G
Stx4
syntaxin 4
decreases expression
ISO
Sarin results in decreased expression of STX4A mRNA
CTD
PMID:19522546
NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
G
Stx6
syntaxin 6
decreases expression
EXP
Sarin results in decreased expression of STX6 mRNA
CTD
PMID:16733813
NCBI chr13:67,332,329...67,378,580
Ensembl chr13:67,332,314...67,378,576
G
Svop
SV2 related protein
decreases expression
EXP
Sarin results in decreased expression of SVOP mRNA
CTD
PMID:16733813
NCBI chr12:42,530,991...42,589,381
Ensembl chr12:42,531,032...42,590,572
G
Synj1
synaptojanin 1
decreases expression
EXP
Sarin results in decreased expression of SYNJ1 mRNA
CTD
PMID:16733813
NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
G
Syt1
synaptotagmin 1
increases expression
ISO
Sarin results in increased expression of SYT1 mRNA
CTD
PMID:19522546
NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
G
Tagln3
transgelin 3
increases expression
EXP
Sarin results in increased expression of TAGLN3 protein
CTD
PMID:28973502
NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
G
Tbcc
tubulin folding cofactor C
decreases expression increases expression
ISO
Sarin results in decreased expression of TBCC mRNA Sarin results in increased expression of TBCC mRNA
CTD
PMID:19522546
NCBI chr 9:14,098,855...14,100,043
Ensembl chr 9:14,098,868...14,100,042
G
Tcfl5
transcription factor like 5
decreases expression
ISO
Sarin results in decreased expression of TCFL5 mRNA
CTD
PMID:19522546
NCBI chr 3:167,734,471...167,754,174
Ensembl chr 3:167,734,473...167,754,282
G
Tf
transferrin
affects binding
ISO
Sarin binds to TF protein Sarin binds to TRF protein
CTD
PMID:18930948
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
G
Tfrc
transferrin receptor
decreases expression
ISO
Sarin results in decreased expression of TFRC mRNA
CTD
PMID:19522546
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
G
Tgfa
transforming growth factor alpha
increases expression
EXP
Sarin results in increased expression of TGFA mRNA
CTD
PMID:16733813
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
G
Thra
thyroid hormone receptor alpha
decreases expression
EXP
Sarin results in decreased expression of THRA mRNA
CTD
PMID:16733813
NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
G
Tm2d1
TM2 domain containing 1
increases expression
ISO
Sarin results in increased expression of TM2D1 mRNA
CTD
PMID:19522546
NCBI chr 5:113,020,793...113,062,134
Ensembl chr 5:113,020,760...113,050,933
G
Tmed10
transmembrane p24 trafficking protein 10
decreases expression
ISO
Sarin results in decreased expression of TMED10 mRNA
CTD
PMID:19522546
NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
G
Tmsb15b2
thymosin beta 15B2
decreases expression
ISO
Sarin results in decreased expression of TMSB15A mRNA
CTD
PMID:19522546
NCBI chr X:100,298,705...100,300,820
Ensembl chr X:100,298,514...100,300,886
G
Tnf
tumor necrosis factor
increases expression
EXP
Sarin results in increased expression of TNF mRNA
CTD
PMID:17301067
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfrsf9
TNF receptor superfamily member 9
increases expression
ISO
Sarin results in increased expression of TNFRSF9 mRNA
CTD
PMID:19522546
NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
G
Top2a
DNA topoisomerase II alpha
decreases expression
ISO
Sarin results in decreased expression of TOP2A mRNA
CTD
PMID:19522546
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
G
Tpi1
triosephosphate isomerase 1
affects expression
EXP
Sarin affects the expression of TPI1 protein
CTD
PMID:28973502
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
G
Tpm1
tropomyosin 1
decreases expression
ISO
Sarin results in decreased expression of TPM1 mRNA
CTD
PMID:19522546
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
G
Traf5
TNF receptor-associated factor 5
increases expression
ISO
Sarin results in increased expression of TRAF5 mRNA
CTD
PMID:19522546
NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709
G
Trpm3
transient receptor potential cation channel, subfamily M, member 3
increases expression
ISO
Sarin results in increased expression of TRPM3 mRNA
CTD
PMID:19522546
NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
G
Tspan3
tetraspanin 3
decreases expression
ISO
Sarin results in decreased expression of TSPAN3 mRNA
CTD
PMID:19522546
NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880
G
Tspo
translocator protein
increases expression multiple interactions
EXP
Sarin results in increased expression of TSPO mRNA; Sarin results in increased expression of TSPO protein [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein; ezogabine inhibits the reaction [Sarin results in increased expression of TSPO protein]
CTD
PMID:27639427 PMID:32209366 PMID:33823148
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
G
Tubb2b
tubulin, beta 2B class IIb
decreases expression
EXP
Sarin results in decreased expression of TUBB2B protein
CTD
PMID:28973502
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
G
Tubb3
tubulin, beta 3 class III
decreases expression
EXP
Sarin results in decreased expression of TUBB3 protein
CTD
PMID:28973502
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
G
Tubg1
tubulin, gamma 1
decreases expression
ISO
Sarin results in decreased expression of TUBG1 mRNA
CTD
PMID:19522546
NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433
G
Ube2g1
ubiquitin-conjugating enzyme E2G 1
decreases expression
ISO
Sarin results in decreased expression of UBE2G1 mRNA
CTD
PMID:19522546
NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568
G
Ube2m
ubiquitin-conjugating enzyme E2M
decreases expression
ISO
Sarin results in decreased expression of UBE2M mRNA
CTD
PMID:19522546
NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026
G
Uchl1
ubiquitin C-terminal hydrolase L1
affects expression
EXP
Sarin affects the expression of UCHL1 protein
CTD
PMID:28973502
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
G
Uchl3
ubiquitin C-terminal hydrolase L3
decreases expression
ISO
Sarin results in decreased expression of UCHL3 mRNA
CTD
PMID:19522546
NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355 Ensembl chr 3:78,485,315...78,527,355
G
Usp14
ubiquitin specific peptidase 14
decreases expression
ISO
Sarin results in decreased expression of USP14 mRNA
CTD
PMID:19522546
NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
G
Vamp3
vesicle-associated membrane protein 3
decreases expression
ISO
Sarin results in decreased expression of VAMP3 mRNA
CTD
PMID:19522546
NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751
G
Vdac1
voltage-dependent anion channel 1
increases expression
ISO
Sarin results in increased expression of VDAC1 mRNA
CTD
PMID:19522546
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
G
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
decreases expression increases expression
ISO
Sarin results in decreased expression of YWHAB mRNA Sarin results in increased expression of YWHAB mRNA
CTD
PMID:19522546
NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
G
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
decreases expression
ISO
Sarin results in decreased expression of YWHAE mRNA
CTD
PMID:19522546
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
G
Zeb1
zinc finger E-box binding homeobox 1
decreases expression
ISO
Sarin results in decreased expression of ZEB1 mRNA
CTD
PMID:19522546
NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
G
Zfp532
zinc finger protein 532
decreases expression
ISO
Sarin results in decreased expression of ZNF532 mRNA
CTD
PMID:19522546
NCBI chr18:59,080,082...59,203,672
Ensembl chr18:59,092,789...59,203,666
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