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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nevadensin
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Accession:CHEBI:7545 term browser browse the term
Definition:A trimethoxyflavone that is flavone substituted by methoxy groups at positions 6, 8 and 4' and hydroxy groups at positions 5 and 7 respectively.
Synonyms:exact_synonym: 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
 related_synonym: 5,7-hydroxy-4',6,8-trimethoxyflavone;   Formula=C18H16O7;   InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3;   InChIKey=KRFBMPVGAYGGJE-UHFFFAOYSA-N;   Pedunculin;   SMILES=COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(O)c(OC)c2o1
 xref: CAS:10176-66-6;   KEGG:C10111;   KNApSAcK:C00001075;   LIPID_MAPS_instance:LMPK12111442
 xref_mesh: MESH:C023982
 xref: PMID:21775221;   PMID:23747095;   PMID:23894034;   PMID:25218219;   Reaxys:1355696
 cyclic_relationship: is_conjugate_acid_of CHEBI:192756


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nevadensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO nevadensin results in increased activity of CASP3 protein CTD PMID:34635930 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO nevadensin results in increased activity of CASP9 protein CTD PMID:34635930 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [nevadensin results in increased abundance of Hydrogen Peroxide] CTD PMID:34635930 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Top1 DNA topoisomerase I decreases activity ISO nevadensin results in decreased activity of TOP1 protein CTD PMID:34635930 NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO nevadensin results in decreased activity of TOP2A protein CTD PMID:34635930 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        biochemical role 19552
          metabolite 19539
            flavone 97
              nevadensin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            organic molecule 19692
                              organic cyclic compound 19482
                                organic heterocyclic compound 18872
                                  oxacycle 17903
                                    benzopyran 11976
                                      1-benzopyran 11730
                                        flavonoid 7230
                                          anthoxanthin 4586
                                            flavones 4586
                                              methoxyflavone 495
                                                trimethoxyflavone 32
                                                  nevadensin 5
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