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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thallium(I) acetate
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Accession:CHEBI:75192 term browser browse the term
Definition:An acetate salt comprising equal numbers of acetate and thallium ions.
Synonyms:exact_synonym: thallium(1+) acetate
 related_synonym: Acetic acid, thallium(1+) salt;   Acetic acid, thallium(I) salt;   Formula=C2H3O2Tl;   InChI=1S/C2H4O2.Tl/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1;   InChIKey=HQOJMTATBXYHNR-UHFFFAOYSA-M;   SMILES=[Tl+].CC([O-])=O;   Thallium acetate;   Thallium monoacetate;   Thallous acetate
 xref: CAS:563-68-8
 xref_mesh: MESH:C026995
 xref: PMID:10699502;   PMID:107679;   PMID:15965099;   PMID:22362959;   PMID:22500883;   PMID:2616067;   PMID:6151386;   PMID:707129;   PMID:899735;   PMID:912438;   Reaxys:3693914


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thallium(I) acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh5 alkB homolog 5, RNA demethylase multiple interactions
decreases expression		 ISO 3-deazaadenosine inhibits the reaction [thallium acetate results in decreased expression of ALKBH5 protein]; ALKBH5 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein] CTD PMID:36745568 NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331 		JBrowse link
G Atp13a3 ATPase 13A3 increases expression
increases stability
multiple interactions		 ISO thallium acetate results in increased expression of ATP13A3 protein
thallium acetate results in increased stability of ATP13A3 mRNA
3-deazaadenosine inhibits the reaction [thallium acetate results in increased expression of and results in increased methylation of ATP13A3 mRNA]; 3-deazaadenosine inhibits the reaction [thallium acetate results in increased expression of ATP13A3 protein]; ALKBH5 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein]; METTL14 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein]; METTL3 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein]; thallium acetate results in increased expression of and results in increased methylation of ATP13A3 mRNA		 CTD PMID:36745568 NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO thallium acetate results in increased expression of H2AX protein CTD PMID:36745568 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit multiple interactions
increases expression		 ISO 3-deazaadenosine inhibits the reaction [thallium acetate results in increased expression of METTL14 protein]; METTL14 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein] CTD PMID:36745568 NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit multiple interactions
increases expression		 ISO 3-deazaadenosine inhibits the reaction [thallium acetate results in increased expression of METTL3 protein]; METTL3 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein] CTD PMID:36745568 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP thallium acetate results in decreased activity of SOD1 protein CTD PMID:15833379 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        poison 18604
          neurotoxin 18211
            thallium(I) acetate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      p-block molecular entity 19811
                        boron group molecular entity 1119
                          thallium molecular entity 7
                            elemental thallium 7
                              monoatomic thallium 7
                                thallium(1+) 7
                                  thallium(I) acetate 6
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