nefazodone - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	nefazodone	go back to main search page
Accession:	CHEBI:7494	browse the term
Definition:	A N-alkylpiperazine that has formula C25H32ClN5O2.
Synonyms:	exact_synonym:	2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
	related_synonym:	1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one; Formula=C25H32ClN5O2; InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3; InChIKey=VRBKIVRKKCLPHA-UHFFFAOYSA-N; SMILES=CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1; nefazodona; nefazodonum
	xref:	Beilstein:4728403; CAS:83366-66-9; DrugBank:DB01149; Drug_Central:1890; KEGG:C07256; KEGG:D08257; LINCS:LSM-4031
	xref_mesh:	MESH:C051752
	xref:	Patent:US4338317; Wikipedia:Nefazodone

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Genes (1757)

nefazodone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APOBEC1 complementation factor

increases expression

nefazodone results in increased expression of A1CF mRNA

NCBI chr 1:229,736,037...229,823,499
Ensembl chr 1:229,736,106...229,824,354

G

arylacetamide deacetylase

decreases expression

nefazodone results in decreased expression of AADAC mRNA

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

aminoadipate aminotransferase

decreases expression

nefazodone results in decreased expression of AADAT mRNA

NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332

G

angio-associated, migratory cell protein

increases expression

nefazodone results in increased expression of AAMP mRNA

NCBI chr 9:75,863,382...75,869,188
Ensembl chr 9:75,863,389...75,868,547

G

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

increases expression

nefazodone results in increased expression of AASDHPPT mRNA

NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966

G

4-aminobutyrate aminotransferase

decreases expression

nefazodone results in decreased expression of ABAT mRNA

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily A member 3

decreases expression

nefazodone results in decreased expression of ABCA3 mRNA

NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745

G

ATP binding cassette subfamily B member 11

multiple interactions
decreases activity
decreases expression

nefazodone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
nefazodone results in decreased activity of ABCB11 protein
nefazodone results in decreased expression of ABCB11 mRNA

PMID:16410371 PMID:20829430 PMID:22646477 PMID:23956101 PMID:24014644 More...

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily B member 4

increases expression
decreases activity
multiple interactions

nefazodone results in increased expression of ABCB4 mRNA
nefazodone results in decreased activity of ABCB4 protein
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCB4 mRNA

PMID:24136188 PMID:28437613 PMID:33819548

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily B member 6

increases expression

nefazodone results in increased expression of ABCB6 mRNA

NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924

G

ATP binding cassette subfamily C member 3

increases expression
multiple interactions
decreases expression

nefazodone results in increased expression of ABCC3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ABCC3 mRNA
nefazodone results in decreased expression of ABCC3 mRNA

PMID:24136188 PMID:32152650

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ABCC4 mRNA
nefazodone results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily C member 6

decreases expression

nefazodone results in decreased expression of ABCC6 mRNA

NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464

G

ATP binding cassette subfamily E member 1

increases expression

nefazodone results in increased expression of ABCE1 mRNA

NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489

G

ATP binding cassette subfamily F member 3

increases expression

nefazodone results in increased expression of ABCF3 mRNA

NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211

G

ATP binding cassette subfamily G member 2

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ATP-binding cassette, subfamily G (WHITE), member 3-like 2

decreases expression

nefazodone results in decreased expression of ABCG3L2 mRNA

NCBI chr14:4,493,259...4,538,264
Ensembl chr14:4,493,262...4,533,306

G

ATP binding cassette subfamily G member 5

increases expression
multiple interactions

nefazodone results in increased expression of ABCG5 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG5 mRNA

PMID:24136188 PMID:33819548

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

ATP binding cassette subfamily G member 8

increases expression
multiple interactions

nefazodone results in increased expression of ABCG8 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG8 mRNA

PMID:24136188 PMID:33819548

NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912

G

abhydrolase domain containing 1

decreases expression

nefazodone results in decreased expression of ABHD1 mRNA

NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514

G

abhydrolase domain containing 2, acylglycerol lipase

decreases expression

nefazodone results in decreased expression of ABHD2 mRNA

NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

nefazodone results in increased expression of ABHD4 mRNA

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

actin binding LIM protein family, member 3

increases expression

nefazodone results in increased expression of ABLIM3 mRNA

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

ankyrin repeat and BTB domain containing 1

increases expression

nefazodone results in increased expression of ABTB1 mRNA

NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:121,299,304...121,305,620

G

acetyl-CoA acyltransferase 1A

increases expression

nefazodone results in increased expression of ACAA1 mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-CoA acyltransferase 2

increases expression

nefazodone results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acetyl-CoA carboxylase alpha

decreases expression

nefazodone results in decreased expression of ACACA mRNA

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA dehydrogenase family, member 11

increases expression

nefazodone results in increased expression of ACAD11 mRNA

NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560

G

ATP citrate lyase

decreases expression

nefazodone results in decreased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

aconitase 1

increases expression

nefazodone results in increased expression of ACO1 mRNA

NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391

G

aconitase 2

increases expression

nefazodone results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 12

increases expression

nefazodone results in increased expression of ACOT12 mRNA

NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536

G

acyl-CoA thioesterase 13

decreases expression

nefazodone results in decreased expression of ACOT13 mRNA

NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851

G

acyl-CoA thioesterase 2

increases expression

nefazodone results in increased expression of ACOT2 mRNA

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA thioesterase 7

increases expression

nefazodone results in increased expression of ACOT7 mRNA

NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309

G

acyl-CoA thioesterase 8

increases expression

nefazodone results in increased expression of ACOT8 mRNA

NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851

G

acyl-CoA oxidase 1

increases expression

nefazodone results in increased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA oxidase 3, pristanoyl

decreases expression

nefazodone results in decreased expression of ACOX3 mRNA

NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205

G

acid phosphatase 1

increases expression

nefazodone results in increased expression of ACP1 mRNA

NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021

G

acid phosphatase 2, lysosomal

decreases expression

nefazodone results in decreased expression of ACP2 mRNA

NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680

G

acyl-CoA synthetase family member 2

decreases expression

nefazodone results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

decreases expression
multiple interactions

nefazodone results in decreased expression of ACSL1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ACSL1 mRNA

PMID:24136188 PMID:33819548

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 4

increases expression

nefazodone results in increased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase long-chain family member 5

decreases expression

nefazodone results in decreased expression of ACSL5 mRNA

NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607

G

acyl-CoA synthetase medium-chain family member 2

increases expression

nefazodone results in increased expression of ACSM2A mRNA

NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116

G

acyl-CoA synthetase short-chain family member 2

decreases expression

nefazodone results in decreased expression of ACSS2 mRNA

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

actin related protein 3

increases expression

nefazodone results in increased expression of ACTR3 mRNA

NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

decreases expression

nefazodone results in decreased expression of ADAMTS7 mRNA

NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328

G

ArfGAP with dual PH domains 2

decreases expression

nefazodone results in decreased expression of ADAP2 mRNA

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

aarF domain containing kinase 5

increases expression

nefazodone results in increased expression of ADCK5 mRNA

NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436

G

adducin 1

increases expression

nefazodone results in increased expression of ADD1 mRNA

NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182

G

adhesion G protein-coupled receptor G1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ADGRG1 mRNA

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor L2

decreases expression

nefazodone results in decreased expression of ADGRL2 mRNA

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH1C mRNA

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

alcohol dehydrogenase 4 (class II), pi polypeptide

increases expression
multiple interactions

nefazodone results in increased expression of ADH4 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH4 mRNA

PMID:24136188 PMID:33819548

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

alcohol dehydrogenase 6 (class V)

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH6 mRNA

NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534

G

alcohol dehydrogenase, iron containing, 1

decreases expression

nefazodone results in decreased expression of ADHFE1 mRNA

NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517

G

ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent

increases expression

nefazodone results in increased expression of ADPRM mRNA

NCBI chr10:51,732,073...51,744,635
Ensembl chr10:51,731,993...51,744,635

G

ADP-ribosylserine hydrolase

increases expression

nefazodone results in increased expression of ADPRS mRNA

NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296

G

adrenoceptor alpha 1B

decreases expression

nefazodone results in decreased expression of ADRA1B mRNA

NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

nefazodone results in increased expression of ADRM1 mRNA

NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195

G

adenylosuccinate lyase

increases expression

nefazodone results in increased expression of ADSL mRNA

NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760

G

AFG3 like matrix AAA peptidase subunit 2

increases expression

nefazodone results in increased expression of AFG3L2 mRNA

NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110

G

afamin

decreases expression

nefazodone results in decreased expression of AFM mRNA

NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870

G

alanine-glyoxylate aminotransferase 2

decreases expression

nefazodone results in decreased expression of AGXT2 mRNA

NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926

G

adenosylhomocysteinase-like 1

increases expression

nefazodone results in increased expression of AHCYL1 mRNA

NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815

G

activator of Hsp90 ATPase activity 1

increases expression

nefazodone results in increased expression of AHSA1 mRNA

NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345

G

androgen-induced 1

increases expression

nefazodone results in increased expression of AIG1 mRNA

NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

nefazodone results in increased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

nefazodone results in increased expression of AIMP2 mRNA

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

aryl-hydrocarbon receptor-interacting protein

increases expression

nefazodone results in increased expression of AIP mRNA

NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122

G

adenylate kinase 3

increases expression

nefazodone results in increased expression of AK3 mRNA

NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625

G

adenylate kinase 4

decreases expression

nefazodone results in decreased expression of AK4 mRNA

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

A-kinase anchoring protein 8 like

decreases expression

nefazodone results in decreased expression of AKAP8L mRNA

NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275

G

aldo-keto reductase family 1 member A1

increases expression

nefazodone results in increased expression of AKR1A1 mRNA

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1, member C1

decreases expression

nefazodone results in decreased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member D1

increases expression
multiple interactions

nefazodone results in increased expression of AKR1D1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of AKR1D1 mRNA

PMID:24136188 PMID:33819548

NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372

G

aldo-keto reductase family 7, member A2

increases expression

nefazodone results in increased expression of AKR7A2 mRNA

NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909

G

aldo-keto reductase family 7 member A3

increases expression
decreases expression
multiple interactions

nefazodone results in increased expression of AKR7A3 mRNA
nefazodone results in decreased expression of AKR7A3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A3 mRNA

PMID:24136188 PMID:32152650

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

AKT1 substrate 1

increases expression

nefazodone results in increased expression of AKT1S1 mRNA

NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677

G

5'-aminolevulinate synthase 1

increases expression

nefazodone results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

albumin

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

increases expression

nefazodone results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member B1

decreases expression

nefazodone results in decreased expression of ALDH1B1 mRNA

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

aldehyde dehydrogenase 1 family, member L1

increases expression

nefazodone results in increased expression of ALDH1L1 mRNA

NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465

G

aldehyde dehydrogenase 3 family, member A2

increases expression

nefazodone results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldolase, fructose-bisphosphate A

increases expression

nefazodone results in increased expression of ALDOA mRNA

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

ALG12, alpha-1,6-mannosyltransferase

increases expression

nefazodone results in increased expression of ALG12 mRNA

NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458

G

ALG3, alpha-1,3- mannosyltransferase

increases expression

nefazodone results in increased expression of ALG3 mRNA

NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912

G

alkB homolog 7

increases expression

nefazodone results in increased expression of ALKBH7 mRNA

NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044

G

alkaline phosphatase, placental

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALPP mRNA

NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606

G

adenosylmethionine decarboxylase 1

increases expression

nefazodone results in increased expression of AMD1 mRNA

NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476

G

AMMECR1 like

decreases expression

nefazodone results in decreased expression of AMMECR1L mRNA

NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,386,903...23,410,920

G

adenosine monophosphate deaminase 3

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of AMPD3 mRNA

NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887

G

aminomethyltransferase

increases expression

nefazodone results in increased expression of AMT mRNA

NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126

G

amylase 2a3

decreases expression

nefazodone results in decreased expression of AMY1A mRNA

NCBI chr 2:201,317,916...201,326,487
Ensembl chr 2:201,317,920...201,326,532

G

angiogenin

decreases expression

nefazodone results in decreased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

angiopoietin-like 3

decreases expression

nefazodone results in decreased expression of ANGPTL3 mRNA

NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957

G

angiopoietin-like 4

decreases expression

nefazodone results in decreased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

nefazodone results in decreased expression of ANKH mRNA

NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187

G

ankyrin repeat domain 13C

decreases expression

nefazodone results in decreased expression of ANKRD13C mRNA

NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433
Ensembl chr 4:247,022,286...247,070,433

G

ankyrin repeat and sterile alpha motif domain containing 4B

decreases expression

nefazodone results in decreased expression of ANKS4B mRNA

NCBI chr 1:174,534,195...174,557,798
Ensembl chr 1:174,547,473...174,557,797

G

anoctamin 10

increases expression

nefazodone results in increased expression of ANO10 mRNA

NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670

G

acidic nuclear phosphoprotein 32 family member A

decreases expression

nefazodone results in decreased expression of ANP32A mRNA

NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443

G

acidic nuclear phosphoprotein 32 family member B

increases expression

nefazodone results in increased expression of ANP32B mRNA

NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717

G

acidic nuclear phosphoprotein 32 family member E

increases expression

nefazodone results in increased expression of ANP32E mRNA

NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054

G

alanyl aminopeptidase, membrane

decreases expression

nefazodone results in decreased expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

ANTXR cell adhesion molecule 2

decreases expression

nefazodone results in decreased expression of ANTXR2 mRNA

NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094

G

annexin A3

decreases expression

nefazodone results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A5

decreases expression

nefazodone results in decreased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

annexin A7

increases expression

nefazodone results in increased expression of ANXA7 mRNA

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

G

aldehyde oxidase 1

increases expression
decreases expression
multiple interactions

nefazodone results in increased expression of AOX1 mRNA
nefazodone results in decreased expression of AOX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AOX1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

adaptor related protein complex 1 subunit mu 1

increases expression

nefazodone results in increased expression of AP1M1 mRNA

NCBI chr16:17,586,886...17,602,410
Ensembl chr16:17,584,730...17,602,403

G

adaptor related protein complex 2 subunit mu 1

increases expression

nefazodone results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

nefazodone results in increased expression of APEX1 mRNA

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

apoptosis inhibitor 5

increases expression

nefazodone results in increased expression of API5 mRNA

NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264

G

amyloid beta precursor like protein 2

decreases expression

nefazodone results in decreased expression of APLP2 mRNA

NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855

G

adipocyte plasma membrane associated protein

decreases expression

nefazodone results in decreased expression of APMAP mRNA

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein A1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein A4

decreases expression

nefazodone results in decreased expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein A5

decreases expression

nefazodone results in decreased expression of APOA5 mRNA

NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816

G

apolipoprotein L2

decreases expression

nefazodone results in decreased expression of APOL3 mRNA

NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558

G

Apol9a-Apol7a readthrough

decreases expression

nefazodone results in decreased expression of APOL7B mRNA

NCBI chr 7:109,118,559...109,149,798
Ensembl chr 7:109,131,064...109,147,649

G

apolipoprotein M

decreases expression

nefazodone results in decreased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

aquaporin 8

increases expression

nefazodone results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

archain 1

increases expression

nefazodone results in increased expression of ARCN1 mRNA

NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247

G

ARF GTPase 1

increases expression

nefazodone results in increased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

ARF GTPase 6

increases expression

nefazodone results in increased expression of ARF6 mRNA

NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114

G

ARF interacting protein 2

decreases expression

nefazodone results in decreased expression of ARFIP2 mRNA

NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336

G

arginase 1

increases expression

nefazodone results in increased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho guanine nucleotide exchange factor 19

decreases expression

nefazodone results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203

G

AT-rich interaction domain 1A

decreases expression

nefazodone results in decreased expression of ARID1A mRNA

NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564

G

ARF like GTPase 4A

increases expression

nefazodone results in increased expression of ARL4A mRNA

NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066

G

ARF like GTPase 5A

increases expression

nefazodone results in increased expression of ARL5A mRNA

NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211

G

ARL6 interacting reticulophagy regulator 1

decreases expression

nefazodone results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994

G

ARF like GTPase 6 interacting protein 4

increases expression

nefazodone results in increased expression of ARL6IP4 mRNA

NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799

G

actin related protein 2/3 complex, subunit 5-like

increases expression

nefazodone results in increased expression of ARPC5L mRNA

NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538
Ensembl chr 9:22,759,876...22,767,538

G

actin-related protein 2/3 complex inhibitor

increases expression

nefazodone results in increased expression of ARPIN mRNA

NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124

G

cAMP-regulated phosphoprotein 19

increases expression

nefazodone results in increased expression of ARPP19 mRNA

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arylsulfatase A

decreases expression

nefazodone results in decreased expression of ARSA mRNA

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

decreases expression

nefazodone results in decreased expression of ASAP2 mRNA

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975

G

anti-silencing function 1A histone chaperone

increases expression

nefazodone results in increased expression of ASF1A mRNA

NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808

G

ASH1 like histone lysine methyltransferase

decreases expression

nefazodone results in decreased expression of ASH1L mRNA

NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

nefazodone results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

asparagine synthetase domain containing 1

increases expression

nefazodone results in increased expression of ASNSD1 mRNA

NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073

G

asparaginase

decreases expression

nefazodone results in decreased expression of ASPG mRNA

NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268

G

activating transcription factor 1

increases expression

nefazodone results in increased expression of ATF1 mRNA

NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670

G

activating transcription factor 4

multiple interactions
increases expression

2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of ATF4 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF4 mRNA
nefazodone results in increased expression of ATF4 mRNA; nefazodone results in increased expression of ATF4 protein

PMID:27613715 PMID:32152650

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 5

increases expression

nefazodone results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

activating transcription factor 6

increases expression
multiple interactions

nefazodone results in increased expression of ATF6 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 7

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATG7 mRNA
nefazodone results in increased expression of ATG7 mRNA

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

G

autophagy related 9A

decreases expression

nefazodone results in decreased expression of ATG9A mRNA

NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

increases expression

nefazodone results in increased expression of ATIC mRNA

NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889

G

atlastin GTPase 2

increases expression

nefazodone results in increased expression of ATL2 mRNA

NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421

G

atlastin GTPase 3

increases expression

nefazodone results in increased expression of ATL3 mRNA

NCBI chr 1:204,680,958...204,727,360
Ensembl chr 1:204,680,968...204,723,354

G

atonal bHLH transcription factor 8

decreases expression

nefazodone results in decreased expression of ATOH8 mRNA

NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168

G

atos homolog A

decreases expression

nefazodone results in decreased expression of ATOSA mRNA

NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549

G

ATPase phospholipid transporting 11A

decreases expression

nefazodone results in decreased expression of ATP11A mRNA

NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640

G

ATP synthase F1 subunit delta

increases expression

nefazodone results in increased expression of ATP5F1D mRNA

NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929

G

ATP synthase inhibitory factor subunit 1

increases expression

nefazodone results in increased expression of ATP5IF1 mRNA

NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668

G

ATP synthase membrane subunit c locus 1

increases expression

nefazodone results in increased expression of ATP5MC1 mRNA

NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase peripheral stalk subunit d

increases expression

nefazodone results in increased expression of ATP5PD mRNA

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATPase H+ transporting accessory protein 2

increases expression

nefazodone results in increased expression of ATP6AP2 mRNA

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

ATPase H+ transporting V0 subunit B

increases expression

nefazodone results in increased expression of ATP6V0B mRNA

NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401

G

ATPase H+ transporting V0 subunit e1

increases expression

nefazodone results in increased expression of ATP6V0E1 mRNA

NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434

G

ATPase H+ transporting V1 subunit A

increases expression

nefazodone results in increased expression of ATP6V1A mRNA

NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694

G

ATPase H+ transporting V1 subunit B2

increases expression

nefazodone results in increased expression of ATP6V1B2 mRNA

NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745

G

ATPase H+ transporting V1 subunit C1

increases expression

nefazodone results in increased expression of ATP6V1C1 mRNA

NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278

G

ATPase H+ transporting V1 subunit D

increases expression

nefazodone results in increased expression of ATP6V1D mRNA

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

ATPase H+ transporting V1 subunit E1

increases expression

nefazodone results in increased expression of ATP6V1E1 mRNA

NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584

G

ATPase H+ transporting V1 subunit F

increases expression

nefazodone results in increased expression of ATP6V1F mRNA

NCBI chr 4:58,067,666...58,070,628

G

ATPase H+ transporting V1 subunit G1

increases expression

nefazodone results in increased expression of ATP6V1G1 mRNA

NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463

G

ATPase H+ transporting V1 subunit H

increases expression

nefazodone results in increased expression of ATP6V1H mRNA

NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962

G

ATP synthase c subunit lysine N-methyltransferase

increases expression

nefazodone results in increased expression of ATPSCKMT mRNA

NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308

G

ATR serine/threonine kinase

decreases expression

nefazodone results in decreased expression of ATR mRNA

NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136

G

attractin

decreases expression

nefazodone results in decreased expression of ATRN mRNA

NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322

G

AU RNA binding methylglutaconyl-CoA hydratase

increases expression

nefazodone results in increased expression of AUH mRNA

NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

nefazodone results in increased expression of AUP1 mRNA

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

arginine vasopressin receptor 1A

decreases expression

nefazodone results in decreased expression of AVPR1A mRNA

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

G

5-azacytidine induced 2

increases expression

nefazodone results in increased expression of AZI2 mRNA

NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847

G

antizyme inhibitor 1

increases expression

nefazodone results in increased expression of AZIN1 mRNA

NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578

G

beta-2 microglobulin

decreases expression

nefazodone results in decreased expression of B2M mRNA

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

bile acid CoA:amino acid N-acyltransferase

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of BAAT mRNA

NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685

G

BAG cochaperone 3

increases expression

nefazodone results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

nefazodone results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

barrier to autointegration nuclear assembly factor 1

increases expression

nefazodone results in increased expression of BANF1 mRNA

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

Bcl-2 binding component 3

increases expression

nefazodone results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

gamma-butyrobetaine hydroxylase 1

decreases expression

nefazodone results in decreased expression of BBOX1 mRNA

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

B-cell receptor-associated protein 29

increases expression

nefazodone results in increased expression of BCAP29 mRNA

NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720

G

branched chain ketoacid dehydrogenase kinase

decreases expression

nefazodone results in decreased expression of BCKDK mRNA

NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633

G

Bcl2-like 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

BCL6, transcription repressor

increases expression

nefazodone results in increased expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

increases expression

nefazodone results in increased expression of BCS1L mRNA

NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938

G

Bet1 golgi vesicular membrane trafficking protein

increases expression

nefazodone results in increased expression of BET1 mRNA

NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617

G

biglycan

decreases expression

nefazodone results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

betaine-homocysteine S-methyltransferase

decreases expression

nefazodone results in decreased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

bridge-like lipid transfer protein family member 3B

increases expression

nefazodone results in increased expression of BLTP3B mRNA

NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720

G

biliverdin reductase B

increases expression

nefazodone results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

bone morphogenetic protein 1

decreases expression

nefazodone results in decreased expression of BMP1 mRNA

NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776

G

bone morphogenetic protein 6

increases expression

nefazodone results in increased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

G

BCL2 interacting protein 3

increases expression

nefazodone results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

BCL2 interacting protein 3 like

increases expression

nefazodone results in increased expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

bolA family member 3

increases expression

nefazodone results in increased expression of BOLA3 mRNA

NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797

G

BOP1 ribosomal biogenesis factor

increases expression

nefazodone results in increased expression of BOP1 mRNA

NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931

G

3'(2'), 5'-bisphosphate nucleotidase 1

increases expression

nefazodone results in increased expression of BPNT1 mRNA

NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503

G

3'(2'), 5'-bisphosphate nucleotidase 2

increases expression

nefazodone results in increased expression of BPNT2 mRNA

NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570

G

bromodomain containing 10

decreases expression

nefazodone results in decreased expression of BRD10 mRNA

NCBI chr 1:227,490,983...227,572,246
Ensembl chr 1:227,491,839...227,571,330

G

bromodomain containing 3

decreases expression

nefazodone results in decreased expression of BRD3 mRNA

NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577

G

biogenesis of ribosomes BRX1

increases expression

nefazodone results in increased expression of BRIX1 mRNA

NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:59,450,614...59,461,495

G

BRICK1 subunit of SCAR/WAVE actin nucleating complex

increases expression

nefazodone results in increased expression of BRK1 mRNA

NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856

G

BTB domain containing 1

decreases expression

nefazodone results in decreased expression of BTBD1 mRNA

NCBI chr 1:135,734,549...135,773,067
Ensembl chr 1:135,734,589...135,771,981

G

basic transcription factor 3

increases expression

nefazodone results in increased expression of BTF3 mRNA

NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
Ensembl chr13:29,659,231...29,666,879

G

BTG anti-proliferation factor 1

decreases expression

nefazodone results in decreased expression of BTG1 mRNA

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

G

BUB3 mitotic checkpoint protein

increases expression

nefazodone results in increased expression of BUB3 mRNA

NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036

G

bystin-like

increases expression

nefazodone results in increased expression of BYSL mRNA

NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339

G

basic leucine zipper and W2 domains 1

increases expression

nefazodone results in increased expression of BZW1 mRNA

NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430

G

similar to human chromosome 17 open reading frame 58

increases expression

nefazodone results in increased expression of C10H17ORF58 mRNA

NCBI chr10:91,972,938...91,977,606
Ensembl chr10:91,972,410...91,977,602

G

similar to human chromosome 5 open reading frame 15

increases expression

nefazodone results in increased expression of C10H5ORF15 mRNA

NCBI chr10:36,563,989...36,576,593
Ensembl chr10:36,563,958...36,576,590

G

similar to human chromosome 1 open reading frame 115

decreases expression

nefazodone results in decreased expression of C13H1ORF115 mRNA

NCBI chr13:96,422,308...96,432,044
Ensembl chr13:96,422,302...96,432,068

G

similar to human chromosome 18 open reading frame 32

increases expression

nefazodone results in increased expression of C18H18ORF32 mRNA

NCBI chr18:68,586,278...68,594,851
Ensembl chr18:68,586,211...68,596,787

G

C1GALT1-specific chaperone 1

increases expression

nefazodone results in increased expression of C1GALT1C1 mRNA

NCBI chr X:117,378,123...117,382,620
Ensembl chr X:117,375,525...117,382,787

G

complement C1q binding protein

increases expression

nefazodone results in increased expression of C1QBP mRNA

NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649

G

complement C1r

decreases expression

nefazodone results in decreased expression of C1R mRNA

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

G

complement C1s

decreases expression

nefazodone results in decreased expression of C1S mRNA

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

G

complement C2

decreases expression

nefazodone results in decreased expression of C2 mRNA

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

G

similar to human chromosome 6 open reading frame 89

increases expression

nefazodone results in increased expression of C20H6ORF89 mRNA

NCBI chr20:7,322,483...7,362,054
Ensembl chr20:7,322,442...7,357,612

G

complement C4B

decreases expression

nefazodone results in decreased expression of C4B mRNA

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

G

complement C5

decreases expression

nefazodone results in decreased expression of C5 mRNA

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

similar to human chromosome 1 open reading frame 210

decreases expression

nefazodone results in decreased expression of C5H1ORF210 mRNA

NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925

G

complement C6

decreases expression

nefazodone results in decreased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

complement C8 alpha chain

decreases expression

nefazodone results in decreased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

complement C8 beta chain

decreases expression

nefazodone results in decreased expression of C8B mRNA

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

G

similar to human chromosome 11 open reading frame 54

increases expression

nefazodone results in increased expression of C8H11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 11 open reading frame 65

increases expression

nefazodone results in increased expression of C8H11ORF65 mRNA

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

complement C9

decreases expression

nefazodone results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

similar to human chromosome 2 open reading frame 69

increases expression

nefazodone results in increased expression of C9H2ORF69 mRNA

NCBI chr 9:58,949,821...58,958,456
Ensembl chr 9:58,949,846...58,958,561

G

calcium binding protein 39

increases expression

nefazodone results in increased expression of CAB39 mRNA

NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544

G

calcium voltage-gated channel subunit alpha1 C

affects activity

nefazodone affects the activity of CACNA1C protein

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CACNA2D1 mRNA

NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969

G

CDK2-associated, cullin domain 1

increases expression

nefazodone results in increased expression of CACUL1 mRNA

NCBI chr 1:259,666,335...259,726,249
Ensembl chr 1:259,668,516...259,726,082

G

calcyclin binding protein

increases expression

nefazodone results in increased expression of CACYBP mRNA

NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177

G

caldesmon 1

decreases expression

nefazodone results in decreased expression of CALD1 mRNA

NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932

G

calmodulin 2

decreases expression

nefazodone results in decreased expression of CALM2 mRNA

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

cell cycle associated protein 1

increases expression

nefazodone results in increased expression of CAPRIN1 mRNA

NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502

G

carbonic anhydrase 3

decreases expression

nefazodone results in decreased expression of CAR3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 8

decreases expression

nefazodone results in decreased expression of CAR8 mRNA

NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374

G

calcium regulated heat stable protein 1

decreases expression

nefazodone results in decreased expression of CARHSP1 mRNA

NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019

G

caspase 3

multiple interactions
increases expression
increases activity

Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP3 protein]
nefazodone results in increased expression of CASP3 mRNA

PMID:22700542 PMID:24136188 PMID:27288927

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

increases activity
multiple interactions

nefazodone results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 9

increases activity

nefazodone results in increased activity of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

decreases expression
multiple interactions

nefazodone results in decreased expression of CAT mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolae associated protein 3

increases expression

nefazodone results in increased expression of CAVIN3 mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

carbonyl reductase 1

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CBR1 mRNA
nefazodone results in increased expression of CBR1 mRNA

PMID:24136188 PMID:32152650

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 4

increases expression

nefazodone results in increased expression of CBR4 mRNA

NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712

G

chromobox 3

increases expression

nefazodone results in increased expression of CBX3 mRNA

NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
Ensembl chr 4:80,546,010...80,559,283

G

coiled-coil domain containing 107

decreases expression

nefazodone results in decreased expression of CCDC107 mRNA

NCBI chr 5:57,749,502...57,752,920
Ensembl chr 5:57,748,999...57,752,918

G

coiled-coil domain containing 47

increases expression

nefazodone results in increased expression of CCDC47 mRNA

NCBI chr10:91,130,303...91,148,829
Ensembl chr10:91,130,303...91,148,881

G

coiled-coil domain containing 6

increases expression

nefazodone results in increased expression of CCDC6 mRNA

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

G

coiled-coil domain containing 80

decreases expression

nefazodone results in decreased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 9

decreases expression

nefazodone results in decreased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cyclin L1

decreases expression

nefazodone results in decreased expression of CCNL1 mRNA

NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368

G

cyclin L2

decreases expression

nefazodone results in decreased expression of CCNL2 mRNA

NCBI chr 5:166,416,940...166,428,997
Ensembl chr 5:166,417,508...166,436,882

G

C-C motif chemokine receptor 2

increases expression
multiple interactions

nefazodone results in increased expression of CCR2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CCR2 mRNA

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

copper chaperone for superoxide dismutase

increases expression

nefazodone results in increased expression of CCS mRNA

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

G

chaperonin containing TCP1 subunit 2

increases expression

nefazodone results in increased expression of CCT2 mRNA

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

chaperonin containing TCP1 subunit 3

increases expression

nefazodone results in increased expression of CCT3 mRNA

NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757

G

chaperonin containing TCP1 subunit 4

increases expression

nefazodone results in increased expression of CCT4 mRNA

NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267

G

chaperonin containing TCP1 subunit 5

increases expression

nefazodone results in increased expression of CCT5 mRNA

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

chaperonin containing TCP1 subunit 6A

increases expression

nefazodone results in increased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

chaperonin containing TCP1 subunit 7

increases expression

nefazodone results in increased expression of CCT7 mRNA

NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580

G

chaperonin containing TCP1 subunit 8

increases expression

nefazodone results in increased expression of CCT8 mRNA

NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079

G

CD14 molecule

increases expression

nefazodone results in increased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD164 molecule

decreases expression

nefazodone results in decreased expression of CD164 mRNA

NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634

G

CD302 molecule

decreases expression

nefazodone results in decreased expression of CD302 mRNA

NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045

G

Cd5 molecule-like

decreases expression

nefazodone results in decreased expression of CD5L mRNA

NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753

G

CD74 molecule

decreases expression

nefazodone results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

Cd81 molecule

decreases expression

nefazodone results in decreased expression of CD81 mRNA

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

G

Cd82 molecule

decreases expression

nefazodone results in decreased expression of CD82 mRNA

NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809

G

cell division cycle 40

increases expression

nefazodone results in increased expression of CDC40 mRNA

NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358

G

cell division cycle 73

increases expression

nefazodone results in increased expression of CDC73 mRNA

NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656

G

cadherin 2

decreases expression

nefazodone results in decreased expression of CDH2 mRNA

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cyclin-dependent kinase 4

increases expression

nefazodone results in increased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 7

increases expression

nefazodone results in increased expression of CDK7 mRNA

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cysteine dioxygenase type 1

decreases expression

nefazodone results in decreased expression of CDO1 mRNA

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

CEA cell adhesion molecule 1

decreases expression

nefazodone results in decreased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

chymotrypsin like elastase 1

decreases expression

nefazodone results in decreased expression of CELA1 mRNA

NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285

G

centromere protein V

increases expression

nefazodone results in increased expression of CENPV mRNA

NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761

G

centrosomal protein 170

decreases expression

nefazodone results in decreased expression of CEP170 mRNA

NCBI chr13:88,669,672...88,754,011
Ensembl chr13:88,670,358...88,732,226

G

carboxylesterase 2H

increases expression

nefazodone results in increased expression of CES2 mRNA

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

cilia and flagella associated protein 20

increases expression

nefazodone results in increased expression of CFAP20 mRNA

NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558

G

cilia and flagella associated protein 298

increases expression

nefazodone results in increased expression of CFAP298 mRNA

NCBI chr11:30,181,916...30,191,302
Ensembl chr11:30,181,905...30,191,346

G

complement factor B

decreases expression

nefazodone results in decreased expression of CFB mRNA

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

G

complement factor H

decreases expression

nefazodone results in decreased expression of CFH mRNA

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

G

complement factor H-related 1

decreases expression

nefazodone results in decreased expression of CFHR1 mRNA

NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592

G

cingulin

decreases expression

nefazodone results in decreased expression of CGN mRNA

NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645

G

cingulin-like 1

decreases expression

nefazodone results in decreased expression of CGNL1 mRNA

NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917

G

cell growth regulator with ring finger domain 1

increases expression

nefazodone results in increased expression of CGRRF1 mRNA

NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037

G

ChaC glutathione specific gamma-glutamylcyclotransferase 2

decreases expression

nefazodone results in decreased expression of CHAC2 mRNA

NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

nefazodone results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763

G

coiled-coil-helix-coiled-coil-helix domain containing 2

increases expression

nefazodone results in increased expression of CHCHD2 mRNA

NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755

G

coiled-coil-helix-coiled-coil-helix domain containing 5

increases expression

nefazodone results in increased expression of CHCHD5 mRNA

NCBI chr 3:116,361,845...116,372,238
Ensembl chr 3:116,361,885...116,367,169

G

coiled-coil-helix-coiled-coil-helix domain containing 6

increases expression

nefazodone results in increased expression of CHCHD6 mRNA

NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216

G

chitinase 3 like 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CHI3L1 mRNA

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

choline kinase alpha

decreases expression

nefazodone results in decreased expression of CHKA mRNA

NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516

G

charged multivesicular body protein 4C

increases expression

nefazodone results in increased expression of CHMP4C mRNA

NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668

G

cysteine and histidine rich domain containing 1

increases expression

nefazodone results in increased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

chondroitin polymerizing factor 2

increases expression

nefazodone results in increased expression of CHPF2 mRNA

NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916

G

choline phosphotransferase 1

increases expression

nefazodone results in increased expression of CHPT1 mRNA

NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103

G

chromatin accessibility complex subunit 1

increases expression

nefazodone results in increased expression of CHRAC1 mRNA

NCBI chr 7:105,013,047...105,016,435
Ensembl chr 7:105,013,015...105,017,136

G

component of inhibitor of nuclear factor kappa B kinase complex

increases expression

nefazodone results in increased expression of CHUK mRNA

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

churchill domain containing 1

increases expression

nefazodone results in increased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

cytosolic iron-sulfur assembly component 2A

increases expression

nefazodone results in increased expression of CIAO2A mRNA

NCBI chr 8:66,670,533...66,682,455
Ensembl chr 8:66,670,483...66,682,455

G

cytokine induced apoptosis inhibitor 1

increases expression

nefazodone results in increased expression of CIAPIN1 mRNA

NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503

G

cell death-inducing DFFA-like effector a

increases expression

nefazodone results in increased expression of CIDEA mRNA

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

cell death-inducing DFFA-like effector c

decreases expression

nefazodone results in decreased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

nefazodone results in decreased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

CDC28 protein kinase regulatory subunit 1B

increases expression

nefazodone results in increased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

CDC28 protein kinase regulatory subunit 2

decreases expression

nefazodone results in decreased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

chloride voltage-gated channel 3

increases expression

nefazodone results in increased expression of CLCN3 mRNA

NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119

G

chloride voltage-gated channel 4

decreases expression

nefazodone results in decreased expression of CLCN4 mRNA

NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238

G

claudin domain containing 1

increases expression

nefazodone results in increased expression of CLDND1 mRNA

NCBI chr11:41,883,120...41,889,471
Ensembl chr11:41,883,134...41,889,354

G

C-type lectin domain family 4, member F

decreases expression

nefazodone results in decreased expression of CLEC4F mRNA

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

CAP-GLY domain containing linker protein 1

increases expression

nefazodone results in increased expression of CLIP1 mRNA

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

increases expression

nefazodone results in increased expression of CLPP mRNA

NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693

G

clathrin, light chain B

increases expression

nefazodone results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

clathrin heavy chain

increases expression

nefazodone results in increased expression of CLTC mRNA

NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737

G

cytidine monophosphate N-acetylneuraminic acid synthetase

increases expression

nefazodone results in increased expression of CMAS mRNA

NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125

G

carboxymethylenebutenolidase homolog

increases expression

nefazodone results in increased expression of CMBL mRNA

NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

nefazodone results in decreased expression of CMTM6 mRNA

NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033

G

CKLF-like MARVEL transmembrane domain containing 8

increases expression

nefazodone results in increased expression of CMTM8 mRNA

NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083

G

CCR4-NOT transcription complex, subunit 11

increases expression

nefazodone results in increased expression of CNOT11 mRNA

NCBI chr 9:41,814,923...41,824,626
Ensembl chr 9:41,814,907...41,824,620

G

cytochrome C oxidase assembly factor 3

increases expression

nefazodone results in increased expression of COA3 mRNA

NCBI chr10:86,220,192...86,221,173
Ensembl chr10:86,220,194...86,221,178

G

cytochrome C oxidase assembly factor 5

increases expression

nefazodone results in increased expression of COA5 mRNA

NCBI chr 9:39,651,459...39,664,870

G

Coenzyme A synthase

increases expression

nefazodone results in increased expression of COASY mRNA

NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841

G

component of oligomeric golgi complex 6

increases expression

nefazodone results in increased expression of COG6 mRNA

NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:137,061,346...137,099,190

G

collagen type XIV alpha 1 chain

decreases expression

nefazodone results in decreased expression of COL14A1 mRNA

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

collagen type XVIII alpha 1 chain

decreases expression

nefazodone results in decreased expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 2 chain

decreases expression

nefazodone results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

decreases expression

nefazodone results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

collagen type VI alpha 1 chain

decreases expression

nefazodone results in decreased expression of COL6A1 mRNA

NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597

G

COMM domain containing 5

increases expression

nefazodone results in increased expression of COMMD5 mRNA

NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764

G

catechol-O-methyltransferase domain containing 1

increases expression

nefazodone results in increased expression of COMTD1 mRNA

NCBI chr15:2,459,783...2,462,895
Ensembl chr15:2,459,783...2,462,895

G

COPI coat complex subunit epsilon

increases expression

nefazodone results in increased expression of COPE mRNA

NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907

G

COP9 signalosome subunit 4

increases expression

nefazodone results in increased expression of COPS4 mRNA

NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887

G

COP9 signalosome subunit 5

increases expression

nefazodone results in increased expression of COPS5 mRNA

NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731

G

COP9 signalosome subunit 7A

increases expression

nefazodone results in increased expression of COPS7A mRNA

NCBI chr 4:157,766,626...157,792,632
Ensembl chr 4:157,766,588...157,773,948

G

coenzyme Q10A

decreases expression

nefazodone results in decreased expression of COQ10A mRNA

NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161

G

coenzyme Q6 monooxygenase

increases expression

nefazodone results in increased expression of COQ6 mRNA

NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657

G

coenzyme Q8A

decreases expression

nefazodone results in decreased expression of COQ8A mRNA

NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431

G

coronin 1C

decreases expression

nefazodone results in decreased expression of CORO1C mRNA

NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179

G

cytochrome c oxidase assembly factor COX14

increases expression

nefazodone results in increased expression of COX14 mRNA

NCBI chr 7:130,852,226...130,854,316

G

cytochrome c oxidase assembly factor COX19

increases expression

nefazodone results in increased expression of COX19 mRNA

NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014

G

ceruloplasmin

decreases expression

nefazodone results in decreased expression of CP mRNA

NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075

G

carboxypeptidase B2

decreases expression

nefazodone results in decreased expression of CPB2 mRNA

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

G

coproporphyrinogen oxidase

increases expression

nefazodone results in increased expression of CPOX mRNA

NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746

G

carboxypeptidase Q

decreases expression

nefazodone results in decreased expression of PGCP mRNA

NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546

G

carbamoyl-phosphate synthase 1

decreases expression

nefazodone results in decreased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

cleavage and polyadenylation specific factor 3

increases expression

nefazodone results in increased expression of CPSF3 mRNA

NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128

G

carnitine palmitoyltransferase 1A

increases expression

nefazodone results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

increases expression

nefazodone results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

carnitine O-acetyltransferase

increases expression

nefazodone results in increased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 3

increases expression

nefazodone results in increased expression of CREB3 mRNA

NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390

G

cAMP responsive element binding protein 3-like 3

increases expression

nefazodone results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

cellular repressor of E1A-stimulated genes 1

increases expression

nefazodone results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich with EGF-like domains 1

increases expression

nefazodone results in increased expression of CRELD1 mRNA

NCBI chr 4:146,631,883...146,641,493
Ensembl chr 4:146,631,883...146,641,499

G

cAMP responsive element modulator

decreases expression

nefazodone results in decreased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

cysteine-rich protein 2

decreases expression

nefazodone results in decreased expression of CRIP2 mRNA

NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065

G

carnitine O-octanoyltransferase

decreases expression

nefazodone results in decreased expression of CROT mRNA

NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109

G

cryptochrome circadian regulator 1

decreases expression

nefazodone results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin beta-gamma domain containing 2

decreases expression

nefazodone results in decreased expression of CRYBG2 mRNA

NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666

G

crystallin, lambda 1

increases expression

nefazodone results in increased expression of CRYL1 mRNA

NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997

G

chromosome segregation 1 like

increases expression

nefazodone results in increased expression of CSE1L mRNA

NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865

G

colony stimulating factor 1

decreases expression
increases expression
multiple interactions

nefazodone results in decreased expression of CSF1 mRNA
nefazodone results in increased expression of CSF1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CSF1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 1 receptor

decreases expression

nefazodone results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

cysteine and glycine-rich protein 1

decreases expression

nefazodone results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystathionine gamma-lyase

decreases expression

nefazodone results in decreased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

cathepsin C

decreases expression

nefazodone results in decreased expression of CTSC mRNA

NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387

G

cathepsin D

increases expression

nefazodone results in increased expression of CTSD mRNA

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin H

decreases expression

nefazodone results in decreased expression of CTSH mRNA

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cathepsin L

increases expression

nefazodone results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cortactin

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of CTTN mRNA

NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164

G

C-X-C motif chemokine ligand 12

decreases expression

nefazodone results in decreased expression of CXCL12 mRNA

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

CXXC finger protein 5

decreases expression

nefazodone results in decreased expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome b5 type A

increases expression

nefazodone results in increased expression of CYB5A mRNA

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b-245 beta chain

decreases expression

nefazodone results in decreased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

CYLD lysine 63 deubiquitinase

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CYLD mRNA
nefazodone results in increased expression of CYLD mRNA

NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
decreases activity

nefazodone results in increased expression of CYP1A1 mRNA
nefazodone results in decreased activity of CYP1A1 protein

PMID:24136188 PMID:33814510

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
multiple interactions

nefazodone results in increased expression of CYP1A2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP1A2 mRNA

PMID:24136188 PMID:33819548

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases activity

nefazodone results in decreased activity of CYP1B1 protein

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 20, subfamily a, polypeptide 1

increases expression

nefazodone results in increased expression of CYP20A1 mRNA

NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123

G

cytochrome P450, family 27, subfamily a, polypeptide 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 12

increases expression

nefazodone results in increased expression of CYP2B12 mRNA

NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases expression
multiple interactions

nefazodone results in decreased expression of CYP2B3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP2B6 mRNA
nefazodone results in decreased expression of CYP2B6 mRNA

PMID:24136188 PMID:32152650

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C18 mRNA

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily c, polypeptide 13

decreases expression

nefazodone results in decreased expression of CYP2C13 mRNA

NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191

G

cytochrome P450, family 2, subfamily c, polypeptide 22

decreases expression

nefazodone results in decreased expression of CYP2C22 mRNA

NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C19 mRNA

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

nefazodone results in increased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily j, polypeptide 3

decreases expression

nefazodone results in decreased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily t, polypeptide 1

decreases expression

nefazodone results in decreased expression of CYP2T1 mRNA

NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression

nefazodone results in increased expression of CYP3A18 mRNA

NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression
increases response to substance
multiple interactions
increases hydroxylation

nefazodone results in decreased expression of CYP3A4 mRNA
CYP3A4 protein results in increased susceptibility to nefazodone
[CYP3A4 protein results in increased hydroxylation of nefazodone] which results in increased abundance of hydroxynefazodone; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of nefazodone]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]

PMID:12584149 PMID:21540358 PMID:27485346 PMID:32152650

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions
increases expression

nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]
nefazodone results in increased expression of CYP3A9 mRNA

PMID:12584149 PMID:24136188

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

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cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

nefazodone results in increased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

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cytochrome P450, family 4, subfamily a, polypeptide 3

increases expression

nefazodone results in increased expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

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cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

nefazodone results in decreased expression of CYP4F1 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

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cytochrome P450, family 4, subfamily f, polypeptide 6

decreases expression

nefazodone results in decreased expression of CYP4F6 mRNA

NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782

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cytochrome P450 family 7 subfamily A member 1

multiple interactions
decreases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA
nefazodone results in decreased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

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cytochrome P450 family 7 subfamily B member 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

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cytochrome P450 family 8 subfamily B member 1

increases expression
multiple interactions

nefazodone results in increased expression of CYP8B1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP8B1 mRNA

PMID:24136188 PMID:33819548

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dishevelled associated activator of morphogenesis 1

decreases expression

nefazodone results in decreased expression of DAAM1 mRNA

NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114

G

dystroglycan 1

decreases expression

nefazodone results in decreased expression of DAG1 mRNA

NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325

G

D-amino-acid oxidase

increases expression

nefazodone results in increased expression of DAO mRNA

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

aspartyl-tRNA synthetase 1

increases expression

nefazodone results in increased expression of DARS1 mRNA

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

DDB1 and CUL4 associated factor 11

increases expression

nefazodone results in increased expression of DCAF11 mRNA

NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669

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DDB1 and CUL4 associated factor 13

increases expression

nefazodone results in increased expression of DCAF13 mRNA

NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142

G

dopa decarboxylase

decreases expression

nefazodone results in decreased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DDHD domain containing 1

decreases expression

nefazodone results in decreased expression of DDHD1 mRNA

NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

nefazodone results in increased expression of DDIT3 mRNA; nefazodone results in increased expression of DDIT3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DDIT3 mRNA

PMID:24136188 PMID:27613715 PMID:32152650

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DEAD-box helicase 17

decreases expression

nefazodone results in decreased expression of DDX17 mRNA

NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193

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DExD-box helicase 21

increases expression

nefazodone results in increased expression of DDX21 mRNA

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

G

DExD-box helicase 39A

increases expression

nefazodone results in increased expression of DDX39A mRNA

NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954

G

DEAD-box helicase 56

increases expression

nefazodone results in increased expression of DDX56 mRNA

NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333

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2,4-dienoyl-CoA reductase 1

increases expression

nefazodone results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

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2,4-dienoyl-CoA reductase 2

increases expression

nefazodone results in increased expression of DECR2 mRNA

NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479

G

delta(4)-desaturase, sphingolipid 1

increases expression

nefazodone results in increased expression of DEGS1 mRNA

NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664

G

DENN domain containing 4C

increases expression

nefazodone results in increased expression of DENND4C mRNA

NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118

G

desumoylating isopeptidase 1

increases expression

nefazodone results in increased expression of DESI1 mRNA

NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845

G

desumoylating isopeptidase 2

increases expression

nefazodone results in increased expression of DESI2 mRNA

NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416

G

Dexi homolog

decreases expression

nefazodone results in decreased expression of DEXI mRNA

NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738

G

diacylglycerol O-acyltransferase 1

increases expression

nefazodone results in increased expression of DGAT1 mRNA

NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299

G

diacylglycerol kinase, alpha

decreases expression

nefazodone results in decreased expression of DGKA mRNA

NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110

G

diacylglycerol kinase zeta

decreases expression

nefazodone results in decreased expression of DGKZ mRNA

NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099

G

dehydrodolichyl diphosphate synthase subunit

increases expression

nefazodone results in increased expression of DHDDS mRNA

NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454

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dehydrogenase/reductase 4

increases expression

nefazodone results in increased expression of DHRS4 mRNA

NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127

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dehydrogenase E1 and transketolase domain containing 1

decreases expression

nefazodone results in decreased expression of DHTKD1 mRNA

NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723

G

DEAH-box helicase 15

increases expression

nefazodone results in increased expression of DHX15 mRNA

NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088

G

diablo, IAP-binding mitochondrial protein

increases expression

nefazodone results in increased expression of DIABLO mRNA

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

DLC1 Rho GTPase activating protein

decreases expression

nefazodone results in decreased expression of DLC1 mRNA

NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439

G

dimethylglycine dehydrogenase

decreases expression

nefazodone results in decreased expression of DMGDH mRNA

NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528

G

dynein axonemal assembly factor 9

decreases expression

nefazodone results in decreased expression of DNAAF9 mRNA

NCBI chr 3:117,918,047...118,052,641
Ensembl chr 3:117,921,620...118,052,630

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

nefazodone results in increased expression of DNAJA1 mRNA

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

G

DnaJ heat shock protein family (Hsp40) member A2

increases expression

nefazodone results in increased expression of DNAJA2 mRNA

NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901

G

DnaJ heat shock protein family (Hsp40) member A3

increases expression

nefazodone results in increased expression of DNAJA3 mRNA

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression
multiple interactions

nefazodone results in increased expression of DNAJB1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB1 mRNA

PMID:24136188 PMID:32152650

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B11

multiple interactions

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB11 mRNA

NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407

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DnaJ heat shock protein family (Hsp40) member B12

increases expression

nefazodone results in increased expression of DNAJB12 mRNA

NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression
multiple interactions

nefazodone results in increased expression of DNAJB9 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJB9 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB9 mRNA

PMID:24136188 PMID:32152650 PMID:33819548

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

DnaJ heat shock protein family (Hsp40) member C1

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC1 mRNA
nefazodone results in increased expression of DNAJC1 mRNA

NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988

G

DnaJ heat shock protein family (Hsp40) member C10

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC10 mRNA
nefazodone results in increased expression of DNAJC10 mRNA

NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719

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DnaJ heat shock protein family (Hsp40) member C12

increases expression
multiple interactions

nefazodone results in increased expression of DNAJC12 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJC12 mRNA

PMID:24136188 PMID:33819548

NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521

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DnaJ heat shock protein family (Hsp40) member C15

increases expression

nefazodone results in increased expression of DNAJC15 mRNA

NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675

G

DnaJ heat shock protein family (Hsp40) member C18

multiple interactions

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC18 mRNA

NCBI chr18:27,269,350...27,303,453
Ensembl chr18:27,269,355...27,298,344

G

DnaJ heat shock protein family (Hsp40) member C19

decreases expression
multiple interactions

nefazodone results in decreased expression of DNAJC19 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC19 mRNA

NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264

G

DnaJ heat shock protein family (Hsp40) member C21

multiple interactions
decreases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC21 mRNA
nefazodone results in decreased expression of DNAJC21 mRNA

NCBI chr 2:59,419,507...59,446,746
Ensembl chr 2:59,419,510...59,446,752

G

DnaJ heat shock protein family (Hsp40) member C3

multiple interactions

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC3 mRNA

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

DnaJ heat shock protein family (Hsp40) member C6

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC6 mRNA
nefazodone results in increased expression of DNAJC6 mRNA

NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448

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DNL-type zinc finger

increases expression

nefazodone results in increased expression of DNLZ mRNA

NCBI chr 3:9,169,948...9,171,727
Ensembl chr 3:9,169,793...9,180,551

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

nefazodone results in increased expression of DNPH1 mRNA

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

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deoxynucleotidyltransferase, terminal, interacting protein 1

increases expression

nefazodone results in increased expression of DNTTIP1 mRNA

NCBI chr 3:153,481,718...153,505,403
Ensembl chr 3:153,481,705...153,505,759

G

dedicator of cytokinesis 9

increases expression

nefazodone results in increased expression of DOCK9 mRNA

NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153

G

deoxyhypusine hydroxylase

increases expression

nefazodone results in increased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

diphthamide biosynthesis 3

increases expression

nefazodone results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

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dolichyl-phosphate mannosyltransferase subunit 1, catalytic

increases expression

nefazodone results in increased expression of DPM1 mRNA

NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536

G

dpy-19 like C-mannosyltransferase 1

decreases expression

nefazodone results in decreased expression of DPY19L1 mRNA

NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751

G

dpy-30 histone methyltransferase complex regulatory subunit

increases expression

nefazodone results in increased expression of DPY30 mRNA

NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432

G

dihydropyrimidinase

decreases expression

nefazodone results in decreased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

down-regulator of transcription 1

increases expression

nefazodone results in increased expression of DR1 mRNA

NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638

G

desmocollin 2

increases expression

nefazodone results in increased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

destrin, actin depolymerizing factor

increases expression

nefazodone results in increased expression of DSTN mRNA

NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379

G

D-aminoacyl-tRNA deacylase 1

increases expression

nefazodone results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659

G

deoxyuridine triphosphatase

increases expression

nefazodone results in increased expression of DUT mRNA

NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771

G

dynein cytoplasmic 1 heavy chain 1

increases expression

nefazodone results in increased expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

dynein light chain LC8-type 2

increases expression

nefazodone results in increased expression of DYNLL2 mRNA

NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805

G

dynein light chain Tctex-type 3

decreases expression

nefazodone results in decreased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

EBNA1 binding protein 2

increases expression

nefazodone results in increased expression of EBNA1BP2 mRNA

NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267

G

EBP, cholestenol delta-isomerase

decreases expression

nefazodone results in decreased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

EBP like

increases expression

nefazodone results in increased expression of EBPL mRNA

NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472

G

enoyl-CoA hydratase 1

increases expression

nefazodone results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

ethylmalonyl-CoA decarboxylase 1

decreases expression

nefazodone results in decreased expression of ECHDC1 mRNA

NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319

G

enoyl-CoA delta isomerase 1

increases expression

nefazodone results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

extracellular matrix protein 1

decreases expression

nefazodone results in decreased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

Ecm29 proteasome adaptor and scaffold

increases expression

nefazodone results in increased expression of ECPAS mRNA

NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860

G

ECSIT signaling integrator

increases expression

nefazodone results in increased expression of ECSIT mRNA

NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390

G

eukaryotic translation elongation factor 1 beta 2

increases expression

nefazodone results in increased expression of EEF1B2 mRNA

NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737

G

eukaryotic translation elongation factor 1 delta

increases expression

nefazodone results in increased expression of EEF1D mRNA

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 1 epsilon 1

increases expression

nefazodone results in increased expression of EEF1E1 mRNA

NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720

G

ephrin A1

decreases expression

nefazodone results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

epidermal growth factor

decreases expression

nefazodone results in decreased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

decreases expression

nefazodone results in decreased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

EH domain binding protein 1

decreases expression

nefazodone results in decreased expression of EHBP1 mRNA

NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332

G

eukaryotic translation initiation factor 1A

increases expression

nefazodone results in increased expression of EIF1A mRNA

NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696

G

eukaryotic translation initiation factor 1A domain containing

increases expression

nefazodone results in increased expression of EIF1AD mRNA

NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658

G

eukaryotic translation initiation factor 2A

multiple interactions
increases expression

2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of EIF2A protein modified form]

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

eukaryotic translation initiation factor 2 alpha kinase 1

decreases expression

nefazodone results in decreased expression of EIF2AK1 mRNA

NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573

G

eukaryotic translation initiation factor 2B subunit epsilon

increases expression

nefazodone results in increased expression of EIF2B5 mRNA

NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419

G

eukaryotic translation initiation factor 2 subunit alpha

increases expression

nefazodone results in increased expression of EIF2S1 mRNA

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 2 subunit beta

increases expression

nefazodone results in increased expression of EIF2S2 mRNA

NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 2 subunit gamma

increases expression

nefazodone results in increased expression of EIF2S3X mRNA

NCBI chr X:58,916,513...58,939,923
Ensembl chr X:58,917,490...58,940,686

G

eukaryotic translation initiation factor 3, subunit B

increases expression

nefazodone results in increased expression of EIF3B mRNA

NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886

G

eukaryotic translation initiation factor 3, subunit C

increases expression

nefazodone results in increased expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 3 subunit E

increases expression

nefazodone results in increased expression of EIF3E mRNA

NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096

G

eukaryotic translation initiation factor 3, subunit G

increases expression

nefazodone results in increased expression of EIF3G mRNA

NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808

G

eukaryotic translation initiation factor 3, subunit I

increases expression

nefazodone results in increased expression of EIF3I mRNA

NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676

G

eukaryotic translation initiation factor 3, subunit L

increases expression

nefazodone results in increased expression of EIF3L mRNA

NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614

G

eukaryotic translation initiation factor 3, subunit M

increases expression

nefazodone results in increased expression of EIF3M mRNA

NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392

G

eukaryotic translation initiation factor 4A1

increases expression

nefazodone results in increased expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

eukaryotic translation initiation factor 4E

increases expression

nefazodone results in increased expression of EIF4E mRNA

NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

nefazodone results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4E binding protein 2

increases expression

nefazodone results in increased expression of EIF4EBP2 mRNA

NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946

G

eukaryotic translation initiation factor 4 gamma 1

increases expression

nefazodone results in increased expression of EIF4G1 mRNA

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

eukaryotic translation initiation factor 5

increases expression

nefazodone results in increased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 5A

increases expression

nefazodone results in increased expression of EIF5A mRNA

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

eukaryotic translation initiation factor 6

increases expression

nefazodone results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

elaC ribonuclease Z 2

increases expression

nefazodone results in increased expression of ELAC2 mRNA

NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614

G

ELAV like RNA binding protein 1

increases expression

nefazodone results in increased expression of ELAVL1 mRNA

NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784

G

elongin C

increases expression

nefazodone results in increased expression of ELOC mRNA

NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
Ensembl chr20:2,661,724...2,677,890

G

ELOVL fatty acid elongase 2

increases expression

nefazodone results in increased expression of ELOVL2 mRNA

NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848

G

ELOVL fatty acid elongase 5

decreases expression

nefazodone results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

elongator acetyltransferase complex subunit 2

increases expression

nefazodone results in increased expression of ELP2 mRNA

NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599

G

ER membrane protein complex subunit 1

increases expression

nefazodone results in increased expression of EMC1 mRNA

NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888

G

ER membrane protein complex subunit 10

increases expression

nefazodone results in increased expression of EMC10 mRNA

NCBI chr 1:94,980,260...94,988,847
Ensembl chr 1:94,943,587...94,988,847

G

ER membrane protein complex subunit 6

increases expression

nefazodone results in increased expression of EMC6 mRNA

NCBI chr10:57,794,072...57,795,671
Ensembl chr10:57,793,685...57,796,217

G

ER membrane protein complex subunit 7

increases expression

nefazodone results in increased expression of EMC7 mRNA

NCBI chr 3:99,263,933...99,274,365
Ensembl chr 3:99,263,980...99,274,360

G

ER membrane protein complex subunit 8

increases expression

nefazodone results in increased expression of EMC8 mRNA

NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543

G

elastin microfibril interfacer 1

decreases expression

nefazodone results in decreased expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

EMAP like 4

decreases expression

nefazodone results in decreased expression of EML4 mRNA

NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879

G

ectodermal-neural cortex 1

multiple interactions
decreases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ENC1 mRNA
nefazodone results in decreased expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

nefazodone results in decreased expression of ENPP1 mRNA

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

ectonucleoside triphosphate diphosphohydrolase 4

increases expression

nefazodone results in increased expression of ENTPD4 mRNA

NCBI chr15:44,630,878...44,658,654
Ensembl chr15:44,630,873...44,658,706

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

nefazodone results in increased expression of ENTPD5 mRNA

NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530

G

endosome associated trafficking regulator 1

increases expression

nefazodone results in increased expression of ENTR1 mRNA

NCBI chr 3:9,200,967...9,207,688
Ensembl chr 3:9,200,967...9,207,688

G

erythrocyte membrane protein band 4.1

increases expression

nefazodone results in increased expression of EPB41 mRNA

NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821

G

erythrocyte membrane protein band 4.1 like 4B

decreases expression

nefazodone results in decreased expression of EPB41L4B mRNA

NCBI chr 5:71,691,706...71,852,583
Ensembl chr 5:71,694,331...71,851,990

G

epoxide hydrolase 1

increases expression
multiple interactions
decreases expression

nefazodone results in increased expression of EPHX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA
nefazodone results in decreased expression of EPHX1 mRNA

PMID:24136188 PMID:32152650

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

nefazodone results in increased expression of EPRS1 mRNA

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

G

epiregulin

increases expression

nefazodone results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ERI1 exoribonuclease family member 3

increases expression

nefazodone results in increased expression of ERI3 mRNA

NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:131,016,126...131,143,329

G

ER lipid raft associated 1

increases expression

nefazodone results in increased expression of ERLIN1 mRNA

NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394

G

endoplasmic reticulum metallopeptidase 1

increases expression

nefazodone results in increased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

ERBB receptor feedback inhibitor 1

decreases expression

nefazodone results in decreased expression of ERRFI1 mRNA

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

G

esterase D

increases expression

nefazodone results in increased expression of ESD mRNA

NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144

G

eukaryotic translation termination factor 1

increases expression

nefazodone results in increased expression of ETF1 mRNA

NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810

G

ETHE1, persulfide dioxygenase

decreases expression

nefazodone results in decreased expression of ETHE1 mRNA

NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052

G

ethanolamine kinase 1

increases expression

nefazodone results in increased expression of ETNK1 mRNA

NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770

G

exosome component 4

increases expression

nefazodone results in increased expression of EXOSC4 mRNA

NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573

G

exosome component 5

increases expression

nefazodone results in increased expression of EXOSC5 mRNA

NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265

G

exosome component 7

increases expression

nefazodone results in increased expression of EXOSC7 mRNA

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270

G

coagulation factor X

decreases expression

nefazodone results in decreased expression of F10 mRNA

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

fatty acid amide hydrolase

decreases expression

nefazodone results in decreased expression of FAAH mRNA

NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677

G

fatty acid binding protein 5

decreases expression

nefazodone results in decreased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid binding protein 7

decreases expression

nefazodone results in decreased expression of FABP7 mRNA

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

fatty acid desaturase 1

decreases expression

nefazodone results in decreased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

decreases expression

nefazodone results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

Fas associated factor 1

increases expression

nefazodone results in increased expression of FAF1 mRNA

NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977

G

family with sequence similarity 117, member B

decreases expression

nefazodone results in decreased expression of FAM117B mRNA

NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483

G

family with sequence similarity 136, member A

increases expression

nefazodone results in increased expression of FAM136A mRNA

NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047

G

family with sequence similarity 193, member B

decreases expression

nefazodone results in decreased expression of FAM193B mRNA

NCBI chr17:9,066,818...9,099,511
Ensembl chr17:9,066,707...9,099,508

G

FAM3 metabolism regulating signaling molecule A

increases expression

nefazodone results in increased expression of FAM3A mRNA

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

G

family with sequence similarity 89, member A

decreases expression

nefazodone results in decreased expression of FAM89A mRNA

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

family with sequence similarity 91, member A1

increases expression

nefazodone results in increased expression of FAM91A1 mRNA

NCBI chr 7:89,969,558...90,007,546
Ensembl chr 7:89,969,605...90,007,556

G

phenylalanyl-tRNA synthetase subunit beta

increases expression

nefazodone results in increased expression of FARSB mRNA

NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045

G

fatty acid synthase

decreases expression

nefazodone results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fibrillarin

increases expression

nefazodone results in increased expression of FBL mRNA

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

F-box protein 21

increases expression

nefazodone results in increased expression of FBXO21 mRNA

NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133

G

F-box protein 31

increases expression

nefazodone results in increased expression of FBXO31 mRNA

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

F-box protein 4

increases expression

nefazodone results in increased expression of FBXO4 mRNA

NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792

G

F-box protein 7

increases expression

nefazodone results in increased expression of FBXO7 mRNA

NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530

G

Fcf1 rRNA-processing protein

increases expression

nefazodone results in increased expression of NOMO1 mRNA

NCBI chr 6:104,617,780...104,629,643
Ensembl chr 6:104,617,770...104,629,643

G

Fc gamma receptor 2A

decreases expression

nefazodone results in decreased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

ferredoxin 1

increases expression

nefazodone results in increased expression of FDX1 mRNA

NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414

G

ferrochelatase

increases expression

nefazodone results in increased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

fibrinogen alpha chain

decreases expression

nefazodone results in decreased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibrinogen beta chain

decreases expression

nefazodone results in decreased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

fibroblast growth factor 21

increases expression

nefazodone results in increased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor receptor 2

decreases expression

nefazodone results in decreased expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibrinogen gamma chain

decreases expression

nefazodone results in decreased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

FGGY carbohydrate kinase domain containing

decreases expression

nefazodone results in decreased expression of FGGY mRNA

NCBI chr 5:110,398,866...110,786,019
Ensembl chr 5:110,398,863...110,786,017

G

fibrinogen-like 1

decreases expression

nefazodone results in decreased expression of FGL1 mRNA

NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093

G

FKBP prolyl isomerase 11

increases expression

nefazodone results in increased expression of FKBP11 mRNA

NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303

G

FKBP prolyl isomerase 1A

increases expression

nefazodone results in increased expression of FKBP1A mRNA

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

G

FKBP prolyl isomerase 3

increases expression

nefazodone results in increased expression of FKBP3 mRNA

NCBI chr 6:83,113,885...83,125,500
Ensembl chr 6:83,113,786...83,127,011

G

FKBP prolyl isomerase 5

decreases expression
multiple interactions

nefazodone results in decreased expression of FKBP5 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

folliculin

increases expression

nefazodone results in increased expression of FLCN mRNA

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

G

flotillin 1

decreases expression

nefazodone results in decreased expression of FLOT1 mRNA

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

G

FLYWCH-type zinc finger 1

increases expression

nefazodone results in increased expression of FLYWCH1 mRNA

NCBI chr10:12,774,644...12,794,373
Ensembl chr10:12,774,653...12,794,267

G

flavin containing dimethylaniline monoxygenase 1

decreases expression
multiple interactions

nefazodone results in decreased expression of FMO1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

fibronectin 1

decreases expression

nefazodone results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

fibronectin type III domain containing 3B

increases expression

nefazodone results in increased expression of FNDC3B mRNA

NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

nefazodone results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions
increases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of FOSL1 mRNA
nefazodone results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box A2

decreases expression

nefazodone results in decreased expression of FOXA2 mRNA

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

G

forkhead box N3

decreases expression

nefazodone results in decreased expression of FOXN3 mRNA

NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401

G

forkhead box O3

increases expression

nefazodone results in increased expression of FOXO3 mRNA

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

follistatin-like 1

decreases expression

nefazodone results in decreased expression of FSTL1 mRNA

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

formimidoyltransferase cyclodeaminase

increases expression

nefazodone results in increased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

ferritin light chain 1

increases expression

nefazodone results in increased expression of FTL1 mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

Fus RNA binding protein

decreases expression

nefazodone results in decreased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FMR1 autosomal homolog 1

increases expression

nefazodone results in increased expression of FXR1 mRNA

NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590

G

frizzled class receptor 1

decreases expression

nefazodone results in decreased expression of FZD1 mRNA

NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

frizzled class receptor 8

decreases expression

nefazodone results in decreased expression of FZD8 mRNA

NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

nefazodone results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

alpha glucosidase

increases expression

nefazodone results in increased expression of GAA mRNA

NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836

G

growth arrest and DNA-damage-inducible, alpha

increases expression

nefazodone results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

galactokinase 1

increases expression

nefazodone results in increased expression of GALK1 mRNA

NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337

G

galactose mutarotase

decreases expression

nefazodone results in decreased expression of GALM mRNA

NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310

G

glycyl-tRNA synthetase 1

increases expression

nefazodone results in increased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest specific 5

increases expression

nefazodone results in increased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

growth arrest specific 6

decreases expression

nefazodone results in decreased expression of GAS6 mRNA

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

GC, vitamin D binding protein

decreases expression

nefazodone results in decreased expression of GC mRNA

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

glycine C-acetyltransferase

decreases expression

nefazodone results in decreased expression of GCAT mRNA

NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473

G

GTP cyclohydrolase 1

increases expression

nefazodone results in increased expression of GCH1 mRNA

NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698

G

glucokinase

decreases expression

nefazodone results in decreased expression of GCK mRNA

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

G

glucokinase regulator

decreases expression

nefazodone results in decreased expression of GCKR mRNA

NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654

G

glutamate-cysteine ligase, catalytic subunit

increases expression

nefazodone results in increased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

nefazodone results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

guanine deaminase

increases expression

nefazodone results in increased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

glycerophosphodiester phosphodiesterase 1

increases expression

nefazodone results in increased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

gem (nuclear organelle) associated protein 6

increases expression

nefazodone results in increased expression of GEMIN6 mRNA

NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612

G

guided entry of tail-anchored proteins factor 4

increases expression

nefazodone results in increased expression of GET4 mRNA

NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053

G

gamma-glutamyl hydrolase

increases expression

nefazodone results in increased expression of GGH mRNA

NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787

G

gamma-glutamyltransferase 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GGT1 mRNA

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

growth hormone inducible transmembrane protein

increases expression

nefazodone results in increased expression of GHITM mRNA

NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879

G

growth hormone receptor

decreases expression

nefazodone results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

gap junction protein, beta 1

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB1 mRNA

NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925

G

gap junction protein, beta 2

increases expression
multiple interactions

nefazodone results in increased expression of GJB2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB2 mRNA

PMID:24136188 PMID:33819548

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

G

glycerol kinase

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GK mRNA

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

glycine decarboxylase

decreases expression

nefazodone results in decreased expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

glutaredoxin

increases expression

nefazodone results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutaredoxin 2

increases expression

nefazodone results in increased expression of GLRX2 mRNA

NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831

G

glutaredoxin 3

increases expression

nefazodone results in increased expression of GLRX3 mRNA

NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010

G

glutaredoxin 5

increases expression

nefazodone results in increased expression of GLRX5 mRNA

NCBI chr 6:123,988,461...123,998,545
Ensembl chr 6:123,988,134...123,998,545

G

glutaminase 2

decreases expression

nefazodone results in decreased expression of GLS2 mRNA

NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426

G

glutamate dehydrogenase 1

decreases expression

nefazodone results in decreased expression of GLUD1 mRNA

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

glutamate-ammonia ligase

decreases expression

nefazodone results in decreased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

ganglioside GM2 activator

decreases expression

nefazodone results in decreased expression of GM2A mRNA

NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757

G

guanine monophosphate synthase

increases expression

nefazodone results in increased expression of GMPS mRNA

NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875

G

G protein subunit alpha i2

decreases expression

nefazodone results in decreased expression of GNAI2 mRNA

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit alpha i3

increases expression

nefazodone results in increased expression of GNAI3 mRNA

NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742

G

GNAS complex locus

decreases expression

nefazodone results in decreased expression of GNAS mRNA

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

nefazodone results in decreased expression of GNE mRNA

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

G protein nucleolar 3

increases expression

nefazodone results in increased expression of GNL3 mRNA

NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392

G

G protein nucleolar 3 like

increases expression

nefazodone results in increased expression of GNL3L mRNA

NCBI chr X:19,961,277...19,994,454
Ensembl chr X:19,958,603...19,994,508

G

glycine N-methyltransferase

decreases expression

nefazodone results in decreased expression of GNMT mRNA

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

glucosamine (N-acetyl)-6-sulfatase

decreases expression

nefazodone results in decreased expression of GNS mRNA

NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151

G

golgi phosphoprotein 3

increases expression

nefazodone results in increased expression of GOLPH3 mRNA

NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049

G

golgi transport 1A

increases expression

nefazodone results in increased expression of GOLT1A mRNA

NCBI chr13:44,760,356...44,773,123
Ensembl chr13:44,760,380...44,773,122

G

golgi associated PDZ and coiled-coil motif containing

increases expression

nefazodone results in increased expression of GOPC mRNA

NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903

G

glutamic-oxaloacetic transaminase 1

decreases expression

nefazodone results in decreased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase 4

increases expression

nefazodone results in increased expression of GPAT4 mRNA

NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901

G

glycerol-3-phosphate dehydrogenase 1

increases expression

nefazodone results in increased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

glucose-6-phosphate isomerase

increases expression

nefazodone results in increased expression of GPI mRNA

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

nefazodone results in decreased expression of GPLD1 mRNA

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

G

G protein-coupled receptor, class C, group 5, member B

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GPRC5B mRNA

NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932

G

glutathione peroxidase 1

decreases expression

nefazodone results in decreased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

decreases expression
multiple interactions

nefazodone results in decreased expression of GPX2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GPX2 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GPX2 mRNA

PMID:32152650 PMID:33819548

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

increases expression

nefazodone results in increased expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

GRAM domain containing 2B

increases expression

nefazodone results in increased expression of GRAMD2B mRNA

NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

nefazodone results in increased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

glutamate-rich WD repeat containing 1

increases expression

nefazodone results in increased expression of GRWD1 mRNA

NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201

G

glutathione-disulfide reductase

increases expression

nefazodone results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

increases expression

nefazodone results in increased expression of GSS mRNA

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 1

multiple interactions
decreases expression

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTA1 mRNA
nefazodone results in decreased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

increases expression

nefazodone results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

increases expression

nefazodone results in increased expression of GSTA3 mRNA

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 4

increases expression

nefazodone results in increased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase mu 1

increases expression
multiple interactions

nefazodone results in increased expression of GSTM1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

increases expression
multiple interactions

nefazodone results in increased expression of GSTM2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM2 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 4

increases expression
multiple interactions

nefazodone results in increased expression of GSTM4 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM4 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase pi 1

increases expression

nefazodone results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase pi 3

decreases expression

nefazodone results in decreased expression of GSTP3 mRNA

NCBI chr 1:201,355,682...201,358,216
Ensembl chr 1:201,355,682...201,358,330

G

general transcription factor IIB

increases expression

nefazodone results in increased expression of GTF2B mRNA

NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651

G

general transcription factor IIH subunit 1

increases expression

nefazodone results in increased expression of GTF2H1 mRNA

NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455

G

general transcription factor III A

increases expression

nefazodone results in increased expression of GTF3A mRNA

NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690

G

guanylate cyclase 1 soluble subunit beta 2

decreases expression

nefazodone results in decreased expression of GUCY1B2 mRNA

NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441

G

glucuronidase, beta

decreases expression

nefazodone results in decreased expression of GUSB mRNA

NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905

G

H1.0 linker histone

decreases expression

nefazodone results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.Z variant histone 2

decreases expression

nefazodone results in decreased expression of H2AZ2 mRNA

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144
Ensembl chr 4:81,293,299...81,312,144
Ensembl chr16:81,293,299...81,312,144

G

H3.3 histone B

increases expression

nefazodone results in increased expression of H3F3B mRNA

NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
Ensembl chr13:101,256,480...101,258,709

G

3-hydroxyacyl-CoA dehydratase 3

increases expression

nefazodone results in increased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

nefazodone results in increased expression of HADHA mRNA

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

nefazodone results in increased expression of HADHB mRNA

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacyl glutathione hydrolase

decreases expression

nefazodone results in decreased expression of HAGH mRNA

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

histidine ammonia lyase

decreases expression

nefazodone results in decreased expression of HAL mRNA

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hepcidin antimicrobial peptide

decreases expression

nefazodone results in decreased expression of HAMP mRNA

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hydroxyacid oxidase 1

decreases expression

nefazodone results in decreased expression of HAO1 mRNA

NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721

G

hydroxyacid oxidase 2

decreases expression

nefazodone results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

histidyl-tRNA synthetase 1

increases expression

nefazodone results in increased expression of HARS1 mRNA

NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740

G

hemoglobin alpha, adult chain 1

decreases expression

nefazodone results in decreased expression of HBA-A1 mRNA

NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin alpha, adult chain 2

decreases expression

nefazodone results in decreased expression of HBA1 mRNA

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
Ensembl chr10:15,307,815...15,338,392

G

histone deacetylase 2

decreases expression

nefazodone results in decreased expression of HDAC2 mRNA

NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609

G

histone deacetylase 6

increases expression

nefazodone results in increased expression of HDAC6 mRNA

NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441

G

heparin binding growth factor

increases expression

nefazodone results in increased expression of HDGF mRNA

NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747

G

helicase with zinc finger 2

decreases expression

nefazodone results in decreased expression of HELZ2 mRNA

NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression
multiple interactions

nefazodone results in increased expression of HERPUD1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HERPUD1 mRNA

PMID:24136188 PMID:32152650

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 6

decreases expression

nefazodone results in decreased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hexosaminidase subunit alpha

decreases expression

nefazodone results in decreased expression of HEXA mRNA

NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013

G

HEXIM P-TEFb complex subunit 1

decreases expression

nefazodone results in decreased expression of HEXIM1 mRNA

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

G

homeostatic iron regulator

increases expression

nefazodone results in increased expression of HFE mRNA

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

G

homogentisate 1, 2-dioxygenase

decreases expression

nefazodone results in decreased expression of HGD mRNA

NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323

G

hepatocyte growth factor

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HGF mRNA

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

hepatocyte growth factor-regulated tyrosine kinase substrate

increases expression

nefazodone results in increased expression of HGS mRNA

NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835

G

hematopoietically expressed homeobox

decreases expression

nefazodone results in decreased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

nefazodone results in increased expression of HIBCH mRNA

NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824

G

HIG1 hypoxia inducible domain family, member 1A

increases expression

nefazodone results in increased expression of HIGD1A mRNA

NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443

G

heat shock protein nuclear import factor hikeshi

increases expression

nefazodone results in increased expression of HIKESHI mRNA

NCBI chr 1:143,825,399...143,849,361
Ensembl chr 1:143,825,923...143,849,363

G

histidine triad nucleotide binding protein 2

increases expression

nefazodone results in increased expression of HINT2 mRNA

NCBI chr 5:57,904,613...57,906,868
Ensembl chr 5:57,904,614...57,907,097

G

histone cluster 1 H4 family member B

decreases expression

nefazodone results in decreased expression of HIST1H4B mRNA

NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370

G

holocarboxylase synthetase

increases expression

nefazodone results in increased expression of HLCS mRNA

NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222

G

hydroxymethylbilane synthase

increases expression

nefazodone results in increased expression of HMBS mRNA

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

nefazodone results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

nefazodone results in decreased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

high mobility group nucleosome binding domain 1

increases expression

nefazodone results in increased expression of HMGN1 mRNA

NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254

G

heme oxygenase 1

increases expression

nefazodone results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A2/B1

decreases expression

nefazodone results in decreased expression of HNRNPA2B1 mRNA

NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249

G

heterogeneous nuclear ribonucleoprotein A/B

increases expression

nefazodone results in increased expression of HNRNPAB mRNA

NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344

G

heterogeneous nuclear ribonucleoprotein F

increases expression

nefazodone results in increased expression of HNRNPF mRNA

NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038

G

4-hydroxy-2-oxoglutarate aldolase 1

decreases expression

nefazodone results in decreased expression of HOGA1 mRNA

NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568

G

homer scaffold protein 1

increases expression

nefazodone results in increased expression of HOMER1 mRNA

NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785

G

hypoxanthine phosphoribosyltransferase 1

increases expression

nefazodone results in increased expression of HPRT1 mRNA

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

hemopexin

multiple interactions

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HPX mRNA

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

G

hydroxysteroid (17-beta) dehydrogenase 4

increases expression

nefazodone results in increased expression of HSD17B4 mRNA

NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952

G

hydroxysteroid (17-beta) dehydrogenase 6

decreases expression

nefazodone results in decreased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

hydroxysteroid dehydrogenase like 2

increases expression

nefazodone results in increased expression of HSDL2 mRNA

NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839

G

heat shock transcription factor 2

increases expression

nefazodone results in increased expression of HSF2 mRNA

NCBI chr20:36,819,864...36,847,490
Ensembl chr20:36,819,864...36,850,174

G

heat shock protein 90 alpha family class A member 1

increases expression

nefazodone results in increased expression of HSP90AA1 mRNA

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268