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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fluticasone furoate
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Accession:CHEBI:74899 term browser browse the term
Definition:A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease.
Synonyms:exact_synonym: 6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate
 related_synonym: Formula=C27H29F3O6S;   GSK 685698;   InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1;   InChIKey=XTULMSXFIHGYFS-VLSRWLAYSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   Veramyst;   fluticasonum furoas;   furoate de fluticasone;   furoato de fluticasona
 xref: CAS:397864-44-7;   Drug_Central:4554;   KEGG:D06315;   PDBeChem:GW6;   PMID:21828231;   PMID:22170807;   PMID:22342538;   PMID:22387656;   PMID:22391079;   PMID:22614920;   PMID:22738148;   PMID:23018908;   PMID:23116485;   PMID:23184737;   PMID:23200625;   PMID:23332861;   PMID:23352226;   PMID:23406601;   PMID:23440247;   PMID:23548539;   PMID:23578031;   PMID:23676578;   PMID:23719680;   PMID:23735179;   PMID:23806459;   PMID:23821392;   PMID:23846316;   Patent:US2009118495;   Patent:WO2010016931;   Patent:WO2011151624;   Patent:WO2011151625;   Patent:WO2012160338;   Reaxys:15686794;   Wikipedia:Fluticasone_furoate


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Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        anti-asthmatic agent 9312
          anti-asthmatic drug 8689
            fluticasone furoate 0
              Breo Ellipta 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18000
                                        furoic acid 18
                                          2-furoic acid 18
                                            2-furoate ester 17
                                              fluticasone furoate 0
                                                Breo Ellipta 0
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