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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antimony trichloride
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Accession:CHEBI:74856 term browser browse the term
Definition:An inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing horn stubs from calves and goats.
Synonyms:exact_synonym: trichlorostibane
 related_synonym: Antimontrichlorid;   Formula=Cl3Sb;   InChI=1S/3ClH.Sb/h3*1H;/q;;;+3/p-3;   InChIKey=FAPDDOBMIUGHIN-UHFFFAOYSA-K;   SMILES=Cl[Sb](Cl)Cl;   SbCl3;   Trichlorostibine;   antimony butter;   antimony chloride;   antimony(III) chloride;   antimony(III) trichloride;   butter of antimony;   caustic antimony;   chlorure antimonieux;   trichloridoantimony;   trichlorure d'antimoine
 xref: CAS:10025-91-9;   KEGG:C15235
 xref_mesh: MESH:C054672
 xref: PMID:1021254;   PMID:1021287;   PMID:1451533;   PMID:15423457;   PMID:17618378;   PMID:17719894;   PMID:18964394;   PMID:19370932;   PMID:2893463;   PMID:29107181;   PMID:4338731;   PMID:5924140;   PMID:663961;   PMID:9657841;   PMID:9772090;   PMID:9903480;   Reaxys:3600276;   Wikipedia:Antimony_trichloride


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antimony trichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 multiple interactions
increases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ATF6 mRNA
antimony trichloride results in increased expression of ATF6 mRNA		 CTD PMID:34091186 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in decreased expression of ATP2A2 mRNA; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of ATP2A2 protein]
antimony trichloride results in decreased expression of ATP2A2 mRNA; antimony trichloride results in decreased expression of ATP2A2 protein		 CTD PMID:34091186 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of CAMK2G mRNA CTD PMID:34091186 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050 		JBrowse link
G Casp12 caspase 12 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of CASP12 mRNA
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of CASP12 mRNA		 CTD PMID:34091186 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression
multiple interactions		 ISO antimony trichloride results in increased cleavage of CASP3 protein
antimony trichloride results in increased expression of CASP3 mRNA
arsenic trichloride promotes the reaction [antimony trichloride results in increased cleavage of CASP3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of CASP3 mRNA]		 CTD PMID:30055241 PMID:34091186 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein CTD PMID:20509621 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of DDIT3 mRNA; antimony trichloride results in increased expression of DDIT3 protein
antimony trichloride promotes the reaction [arsenic trichloride results in increased expression of DDIT3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 protein]		 CTD PMID:34091186 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 multiple interactions
increases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ERN2 mRNA
antimony trichloride results in increased expression of ERN2 mRNA		 CTD PMID:34091186 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of HSPA5 mRNA; antimony trichloride results in increased expression of HSPA5 protein
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of HSPA5 protein; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of HSPA5 mRNA]		 CTD PMID:34091186 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of ITPR2 mRNA
antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of ITPR2 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of ITPR2 mRNA]		 CTD PMID:34091186 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO antimony trichloride results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]		 CTD PMID:30055241 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO antimony trichloride results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]		 CTD PMID:30055241 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of MAPK8 protein
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of MAPK8 protein]		 CTD PMID:34091186 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Ryr2 ryanodine receptor 2 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of RYR2 mRNA; antimony trichloride results in increased expression of RYR2 protein
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of RYR2 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in decreased expression of RYR2 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of RYR2 protein]		 CTD PMID:34091186 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions		 ISO antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]		 CTD PMID:30055241 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of TRP53 mRNA; antimony trichloride results in increased expression of TRP53 protein
antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of TRP53 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of TRP53 protein]		 CTD PMID:34091186 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
increases expression		 ISO [arsenic trichloride co-treated with antimony trichloride] results in increased expression of XBP1 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of XBP1 protein]; arsenic trichloride inhibits the reaction [antimony trichloride results in increased expression of XBP1 protein]
antimony trichloride results in increased expression of XBP1 mRNA; antimony trichloride results in increased expression of XBP1 protein		 CTD PMID:34091186 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
affects binding		 ISO antimony trichloride inhibits the reaction [XPA protein binds to Zinc]
antimony trichloride binds to XPA protein		 CTD PMID:20509621 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      chemical role 19473
        acceptor 17931
          Lewis acid 7650
            antimony trichloride 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      halogen 18673
                        chlorine atom 18457
                          chlorine molecular entity 18457
                            elemental chlorine 8778
                              monoatomic chlorine 8763
                                chloride 8763
                                  chloride salt 8763
                                    inorganic chloride 8526
                                      antimony trichloride 18
paths to the root