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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ac-Asp-Glu
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Accession:CHEBI:73688 term browser browse the term
Definition:A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage.
Synonyms:exact_synonym: N-acetyl-L-alpha-aspartyl-L-glutamic acid
 related_synonym: Formula=C11H16N2O8;   InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1;   InChIKey=OPVPGKGADVGKTG-BQBZGAKWSA-N;   N-Ac-D-E;   N-Acetyl-1-aspartylglutamic acid;   N-acetyl-L-Asp-L-Glu;   N-acetylaspartylglutamic acid;   NAAG;   SMILES=CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O;   isospaglumic acid
 xref: CAS:3106-85-2;   KEGG:C12270
 xref_mesh: MESH:C027172
 xref: Wikipedia:N-Acetylaspartylglutamic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:76931



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Ac-Asp-Glu term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folh1 folate hydrolase 1 affects binding
multiple interactions
ISO isospaglumic acid binds to FOLH1 protein
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]
CTD PMID:24508213 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      chemical role 19495
        antioxidant 16147
          N-acetyl-L-aspartic acid 1
            Ac-Asp-Glu 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbon oxoacid 18694
                                    carboxylic acid 18691
                                      carboacyl group 17723
                                        univalent carboacyl group 17723
                                          carbamoyl group 17576
                                            carboxamide 17576
                                              N-acyl-amino acid 10130
                                                N-acyl-L-amino acid 2067
                                                  N-acyl-L-alpha-amino acid 45
                                                    N-acyl-L-aspartic acid 1
                                                      N-acetyl-L-aspartic acid 1
                                                        Ac-Asp-Glu 1
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