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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:NS-398
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Accession:CHEBI:73458 term browser browse the term
Definition:A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Synonyms:related_synonym: N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide;   NS398
 xref: CAS:123653-11-2
 xref_mesh: MESH:C080955
 xref: Patent:US2010152297;   Reaxys:6611485;   lincs.smallmolecule:LSM-6616;   pubmed:22349912;   pubmed:23132402;   pubmed:23398724;   pubmed:23456767;   pubmed:23545701;   pubmed:23597562;   wikipedia.en:NS-398
 chemrof_formula: C13H18N2O5S
 chemrof_smiles: CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1OC1CCCCC1
 chemrof_inchi: InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3
 chemrof_inchikey: KTDZCOWXCWUPEO-UHFFFAOYSA-N
 cyclic_relationship: has_functional_parent CHEBI:17064


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NS-398 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
decreases expression 		ISO Methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCA1 mRNA]; ZM 241385 inhibits the reaction [Methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCA1 mRNA]] CTD PMID:19035488 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCB1 mRNA 		CTD PMID:21745461 PMID:23466342 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCC1 mRNA CTD PMID:21745461 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [VEGFA protein results in increased expression of ACE protein] CTD PMID:11158990 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ACTA2 protein] CTD PMID:27697457 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Agt angiotensinogen multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [AGT protein results in increased abundance of Prostaglandins E] CTD PMID:19145780 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
increases activity
increases expression 		ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; caffeic acid inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of ALOX15 protein]; GATA6 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein 		CTD PMID:10904086 PMID:11406566 PMID:11861401 NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723 		JBrowse link
G Arg1 arginase 1 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of ARG1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [IL4 protein results in increased expression of ARG1 mRNA] CTD PMID:26748080 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] CTD PMID:19861503 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with rosiglitazone] results in increased expression of BAX mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with rosiglitazone] results in increased expression of BAX protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of BAX mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of BAX protein 		CTD PMID:19056168 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression 		ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with rosiglitazone] results in decreased expression of BCL2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with rosiglitazone] results in decreased expression of BCL2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of BCL2 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of BCL2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of BCL2 protein] 		CTD PMID:16230411 PMID:19056168 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Capn1 calpain 1 decreases expression EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CAPN1 protein CTD PMID:28342779 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Capn2 calpain 2 decreases expression EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CAPN2 protein CTD PMID:28342779 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Casp2 caspase 2 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]] CTD PMID:29242151 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity 		ISO
EXP 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; PTGS2 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP3 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP3 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein] 		CTD PMID:12414664 PMID:14687664 PMID:21745461 PMID:21873648 PMID:32115946 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein] CTD PMID:14687664 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases activity ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP8 protein CTD PMID:12414664 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP9 protein
PTGS2 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP9 protein] 		CTD PMID:12414664 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
decreases expression 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [CAT protein results in decreased abundance of Dinoprostone]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CAT protein 		CTD PMID:10899936 PMID:18848576 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CAV1 protein CTD PMID:18848576 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CCL2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein] CTD PMID:11230753 PMID:18096868 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCNB1 protein CTD PMID:11504793 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCND1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCND1 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of CCND1 mRNA]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of CCND1 mRNA]]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCND1 mRNA] 		CTD PMID:11504793 PMID:29242151 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CCNE2 protein] CTD PMID:24184161 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Ccnk cyclin K decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCNK mRNA CTD PMID:11494140 NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:132,854,700...132,877,602 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CDK2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]; PTGS2 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CDK2 protein] 		CTD PMID:14566837 PMID:24184161 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
increases activity 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CDKN1A protein 		CTD PMID:14566837 PMID:14567460 PMID:16376453 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1B protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in decreased expression of CDKN1B protein] 		CTD PMID:14567460 PMID:24184161 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit increases expression
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CHRNA4 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with Nicotine] inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CHRNA4 protein] 		CTD PMID:15551346 NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CHRNB4 protein CTD PMID:15551346 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248 		JBrowse link
G Col10a1 collagen type X alpha 1 chain multiple interactions ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 protein CTD PMID:27050768 NCBI chr20:39,737,536...39,744,518
Ensembl chr20:39,716,822...39,751,440 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]] CTD PMID:18096868 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide analog results in decreased expression of CYP19A1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP19A1 mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide analog results in decreased activity of CYP19A1 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CYP19A1 protein 		CTD PMID:15964185 PMID:16480277 PMID:20678559 PMID:28571770 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein] CTD PMID:20093341 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
decreases expression 		ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 protein]; Methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA]; Methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 protein]; ZM 241385 inhibits the reaction [Methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA]]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 protein 		CTD PMID:19035488 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of DDIT3 protein CTD PMID:17709599 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dnm2 dynamin 2 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of DNM2 mRNA CTD PMID:11494140 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of EGR1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of EGR1 protein] CTD PMID:11595463 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G F2 coagulation factor II, thrombin decreases activity
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of F2
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [F2 protein results in increased abundance of Thromboxane A2 metabolite]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [F2 protein results in increased abundance of Thromboxane B2] 		CTD PMID:10027849 PMID:17379757 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Faslg Fas ligand multiple interactions ISO [sodium arsenite co-treated with N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide] results in increased localization of and results in increased stability of FASLG protein CTD PMID:16487513 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fat1 FAT atypical cadherin 1 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of FAT1 mRNA CTD PMID:11494140 NCBI chr16:53,909,759...54,029,175
Ensembl chr16:53,909,556...54,028,609 		JBrowse link
G Flg filaggrin multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Particulate Matter results in decreased expression of FLG protein] CTD PMID:31884678 NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968 		JBrowse link
G Gata6 GATA binding protein 6 multiple interactions
decreases expression 		ISO GATA6 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of GATA6 protein 		CTD PMID:11861401 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of GDF15 protein CTD PMID:15180942 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of GPX1 protein CTD PMID:18848576 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein] CTD PMID:21873648 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions
decreases expression 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased activity of MAPK1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased activity of MAPK3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased expression of MMP9]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of HGF mRNA 		CTD PMID:10807402 PMID:11981761 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein] CTD PMID:16527254 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Zymosan results in increased expression of HMOX1 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Pravastatin results in increased expression of HMOX1 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [arsenic trioxide results in increased expression of HMOX1] 		CTD PMID:11454666 PMID:20368269 PMID:23649692 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Dinoprostone inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cadmium Chloride results in increased expression of ICAM1 mRNA]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cadmium Chloride results in increased expression of ICAM1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cadmium Chloride results in increased expression of ICAM1 protein] CTD PMID:16777358 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifng interferon gamma multiple interactions EXP
ISO 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Dinoprostone]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of ARG1 mRNA] 		CTD PMID:12911628 PMID:26748080 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dihematoporphyrin Ether results in decreased expression of IL10 protein] CTD PMID:16230411 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:11230753 PMID:15167967 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO
EXP 		Dexamethasone inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1B protein results in increased abundance of Dinoprost]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL1B protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Silicon Dioxide results in increased secretion of IL1B protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Zymosan analog results in increased expression of IL1B protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Acetic Acid results in increased expression of IL1B protein] 		CTD PMID:11286988 PMID:11376495 PMID:12517972 PMID:12946449 PMID:16354411 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [IL4 protein results in increased expression of ARG1 mRNA] CTD PMID:26748080 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of IL6 mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Silicon Dioxide results in increased secretion of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Zymosan analog results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] 		CTD PMID:12649040 PMID:12946449 PMID:15379866 PMID:17709599 PMID:19580863 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 multiple interactions
increases secretion 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Glucose results in increased secretion of INS protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased secretion of INS protein 		CTD PMID:17192482 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Lep leptin multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein] CTD PMID:28571770 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO
EXP 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased phosphorylation of MAPK1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased activity of MAPK1 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol promotes the reaction [MAPK1 protein binds to PTGS2 protein]] 		CTD PMID:11981761 PMID:16376453 PMID:17984113 PMID:26358519 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		ISO
EXP 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased phosphorylation of MAPK3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased activity of MAPK3 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol promotes the reaction [MAPK3 protein binds to PTGS2 protein]] 		CTD PMID:11981761 PMID:16376453 PMID:17984113 PMID:26358519 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of MKI67 mRNA CTD PMID:27318970 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of MMP9 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dronabinol results in increased expression of MMP9 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [HGF results in increased expression of MMP9]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of MMP9 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA] CTD PMID:11981761 PMID:16330497 PMID:19804834 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of MYC mRNA]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of MYC mRNA]] CTD PMID:29242151 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of NFKBIA protein CTD PMID:12517972 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] CTD PMID:26748080 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein] CTD PMID:16230411 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pawr pro-apoptotic WT1 regulator increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PAWR mRNA CTD PMID:10833474 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492 		JBrowse link
G Pcdh7 protocadherin 7 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PCDH7 mRNA CTD PMID:11494140 NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665 		JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PCLAF mRNA CTD PMID:11494140 NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PDCD4 mRNA CTD PMID:11494140 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [PDGFA results in increased abundance of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [PDGFA results in increased abundance of Epoprostenol] CTD PMID:19201774 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PDLIM5 mRNA CTD PMID:11494140 NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [docetaxel results in increased expression of POMC mRNA] CTD PMID:22902858 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases expression 		ISO
EXP 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [ciglitazone results in increased expression of PPARA mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [pirinixic acid results in increased expression of PPARA mRNA]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PPARA mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Pravastatin affects the localization of PPARA protein] 		CTD PMID:11840453 PMID:20368269 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
increases localization 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cannabidiol affects the localization of PPARG protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Celecoxib affects the localization of PPARG protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [ciglitazone results in increased expression of PPARG mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Lovastatin analog affects the localization of PPARG protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [pirinixic acid results in increased expression of PPARG mRNA]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PPARG mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased localization of PPARG protein 		CTD PMID:11840453 PMID:12517972 PMID:23220503 PMID:23943857 PMID:26863638 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PPFIA1 mRNA CTD PMID:11494140 NCBI chr 1:209,070,608...209,147,740
Ensembl chr 1:209,070,608...209,150,265 		JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions
decreases expression 		EXP
ISO 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGER2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGER2 protein] 		CTD PMID:17709599 PMID:21873648 PMID:32115946 NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP
ISO 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGER4 protein] 		CTD PMID:21873648 PMID:32115946 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity
multiple interactions 		ISO
EXP 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS1 protein
[SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Cadmium Chloride results in increased expression of PTGS1 mRNA] 		CTD PMID:9258749 PMID:15155531 PMID:15843042 PMID:21873648 PMID:25645360 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
decreases expression
increases activity
increases expression
increases response to substance 		ISO
EXP 		N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with [Vanadates results in increased abundance of Vanadium]] results in increased expression of PTGS2 protein; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides results in increased phosphorylation of TP53 protein]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [CGB3 protein results in increased chemical synthesis of Dinoprost]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Resveratrol results in increased activity of TP53 protein]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprostone; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Ceramides; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to o,p'-DDT; Dexamethasone inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]]; Dexamethasone inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of and results in increased activity of PTGS2 protein]; Dinoprostone inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 mRNA] which results in increased chemical synthesis of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cadmium Chloride results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Celecoxib results in increased activity of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cumene hydroperoxide results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of and results in increased activity of PTGS2 protein; PTGS2 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CDK2 protein]; PTGS2 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP9 protein]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol results in increased expression of PTGS2 mRNA]]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGS2; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGS2 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGS2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of PTGS2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PTGS2 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of PTGS2 protein
PTGS2 protein results in increased susceptibility to N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprost; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased secretion of Dinoprost; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased secretion of Dinoprostone; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Lipopolysaccharides; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Norepinephrine; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to VX-agent; [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]; Dinoprostone results in decreased susceptibility to [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein]; Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [PTGS2 protein results in increased abundance of Dinoprost]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol promotes the reaction [MAPK1 protein binds to PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol promotes the reaction [MAPK3 protein binds to PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [trans-10,cis-12-conjugated linoleic acid results in increased chemical synthesis of Dinoprost]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprost; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprostone; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased abundance of Thromboxane A2; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 protein; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dibutyl Phthalate results in increased expression of PTGS2 protein] 		CTD PMID:9258749 PMID:9705326 PMID:10485483 PMID:10594344 PMID:10791687 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein CTD PMID:27050768 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression 		ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of SOD2 protein 		CTD PMID:12031898 PMID:18848576 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of CCND1 mRNA]]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in decreased expression of MYC mRNA]]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of PTGS2 mRNA]]; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCND1 mRNA] CTD PMID:29242151 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:18809416 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cisplatin results in increased expression of TGFB1 mRNA] CTD PMID:21256724 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dronabinol results in increased expression of TIMP1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] CTD PMID:16330497 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Acetic Acid results in increased expression of TNF protein] 		CTD PMID:9576062 PMID:11230753 PMID:11376495 PMID:15379866 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of TNFRSF10A protein CTD PMID:15572759 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with Cycloheximide]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with resveratrol] CTD PMID:18222423 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression 		ISO
EXP 		[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides results in increased phosphorylation of TP53 protein]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [resveratrol results in increased activity of TP53 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of TP53 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of TP53 mRNA 		CTD PMID:16928824 PMID:17984113 PMID:18446786 PMID:23495037 PMID:29242151 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of TPX2 mRNA CTD PMID:11494140 NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 results in increased phosphorylation of TRPV1 protein] CTD PMID:18809416 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of EGR1 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of EGR1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFA protein results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [VEGFA protein results in increased expression of ACE protein] CTD PMID:11158990 PMID:11595463 PMID:18596194 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in decreased expression of CDKN1B protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CCNE2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein] CTD PMID:24184161 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
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