Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:iodocyanopindolol
go back to main search page
Accession:CHEBI:73370 term browser browse the term
Definition:An indole that is 1H-indole substituted at positions 2, 3 and 7 by cyano, iodo and 3-(tert-butylamino)-2-hydroxypropoxy groups respectively.
Synonyms:exact_synonym: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-3-iodo-1-indole-2-carbonitrile
 related_synonym: 4-(2-Hydroxy-3-(tert-butylamino)propoxy)-3-iodo-1H-indole-2-carbonitrile;   Formula=C16H20IN3O2;   InChI=1S/C16H20IN3O2/c1-16(2,3)19-8-10(21)9-22-13-6-4-5-11-14(13)15(17)12(7-18)20-11/h4-6,10,19-21H,8-9H2,1-3H3;   InChIKey=JBLUMBNIBNHRSO-UHFFFAOYSA-N;   SMILES=CC(C)(C)NCC(O)COc1cccc2[nH]c(C#N)c(I)c12
 xref: CAS:80180-26-3
 xref_mesh: MESH:D020120
 xref: PMID:20601048;   PMID:21734891;   PMID:23597562;   Reaxys:8716017;   Wikipedia:Iodocyanopindolol


show annotations for term's descendants           Sort by:
iodocyanopindolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions
affects binding		 ISO
EXP		 Albuterol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; CGP 20712A inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Epinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; ICI 89406 inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Norepinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; soterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Terbutaline inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]
Albuterol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Epinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; ICI 118551 inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; ICI 89406 inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Norepinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; soterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Terbutaline inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]		 CTD PMID:8096834 PMID:9260993 PMID:10344530 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
affects binding		 ISO
EXP		 ICI 118551 inhibits the reaction [Iodocyanopindolol binds to ADRB2 protein] CTD PMID:9260993 PMID:10344530 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding
multiple interactions		 EXP Iodocyanopindolol binds to HTR1B protein
sarpogrelate inhibits the reaction [Iodocyanopindolol binds to HTR1B protein]; sarpogrelate metabolite inhibits the reaction [Iodocyanopindolol binds to HTR1B protein]		 CTD PMID:8937629 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      group 19831
        pseudohalo group 4581
          cyano group 4581
            nitrile 4581
              iodocyanopindolol 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18300
                                    organic heterobicyclic compound 17242
                                      benzopyrrole 9742
                                        indoles 9430
                                          iodocyanopindolol 3
paths to the root