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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:exopolysaccharide
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Accession:CHEBI:72813 term browser browse the term
Definition:A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.
Synonyms:related_synonym: exopolysaccharides;   extracellular polymeric substance;   extracellular polymeric substances
 xref: MetaCyc:Exopolysaccharides;   PMID:11160795;   PMID:11785425;   PMID:1444258;   PMID:15738217;   PMID:16075348;   PMID:17440912;   PMID:18097339;   PMID:19453747;   PMID:20172021;   PMID:20631870;   PMID:20718297;   PMID:2688547;   PMID:6354590;   Wikipedia:Exopolysaccharide;   Wikipedia:Extracellular_polymeric_substance



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(1->3)-beta-D-glucan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tslp thymic stromal lymphopoietin increases expression ISO (1->3)-beta-D-glucan increases expression of TSLP mRNA and protein in corneal epithelial cells RGD PMID:26874828 RGD:38549373 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
JBrowse link
alginic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan increases expression ISO alginic acid results in increased expression of ACAN mRNA CTD PMID:16371897 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
JBrowse link
G Atg12 autophagy related 12 increases expression EXP Alginic Acid results in increased expression of ATG12 protein CTD PMID:35066102 NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
JBrowse link
G Atg7 autophagy related 7 increases expression EXP Alginic Acid results in increased expression of ATG7 protein CTD PMID:35066102 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression EXP Alginic Acid results in decreased expression of BCL2 protein CTD PMID:35066102 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression EXP Alginic Acid results in decreased expression of BCL2L1 protein CTD PMID:35066102 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Becn1 beclin 1, autophagy related increases expression EXP Alginic Acid results in increased expression of BECN1 protein CTD PMID:35066102 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
EXP Alginic Acid results in increased expression of CASP3 protein
Alginic Acid results in increased cleavage of CASP3 protein
CTD PMID:35066102 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:35066102 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 increases expression EXP Alginic Acid results in increased expression of CASP9 protein CTD PMID:35066102 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase decreases expression EXP Alginic Acid results in decreased expression of CAT protein CTD PMID:35066102 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Col10a1 collagen, type X, alpha 1 increases expression ISO alginic acid results in increased expression of COL10A1 mRNA CTD PMID:16371897 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression EXP Alginic Acid results in increased expression of CYP17A1 protein CTD PMID:35066102 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression EXP Alginic Acid results in decreased expression of CYP19A1 protein CTD PMID:35066102 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Alginic Acid results in decreased expression of FSHR protein CTD PMID:35066102 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
JBrowse link
G Gpx5 glutathione peroxidase 5 decreases expression EXP Alginic Acid results in decreased expression of GPX5 protein CTD PMID:35066102 NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation EXP Alginic Acid results in increased lipidation of MAP1LC3B protein CTD PMID:35066102 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:35066102 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Rab7 RAB7, member RAS oncogene family increases expression EXP Alginic Acid results in increased expression of RAB7 protein CTD PMID:35066102 NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression EXP Alginic Acid results in decreased expression of SOD1 protein CTD PMID:35066102 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression EXP Alginic Acid results in decreased expression of SOD2 protein CTD PMID:35066102 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sqstm1 sequestosome 1 decreases expression EXP Alginic Acid results in decreased expression of SQSTM1 protein CTD PMID:35066102 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Alginic Acid results in decreased expression of STAR protein CTD PMID:35066102 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; alginic acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
chitosan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of ABCA1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in decreased expression of ABCA1 mRNA] CTD PMID:28987369 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases phosphorylation
ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of AKT1 protein]
Chitosan results in decreased phosphorylation of AKT1 protein
CTD PMID:28732690 PMID:36706893 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of ALAD protein] CTD PMID:22704994 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney increases expression ISO Chitosan results in increased expression of ALPL mRNA; Chitosan results in increased expression of ALPL protein CTD PMID:25246786 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of AOX1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in decreased expression of AOX1 mRNA] CTD PMID:28987369 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
JBrowse link
G Arb2a ARB2 cotranscriptional regulator A multiple interactions
increases expression
ISO ARB2A protein affects the reaction [Chitosan results in decreased expression of CPE protein]; ARB2A protein affects the reaction [Chitosan results in decreased expression of MMP9 protein]; ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK1 protein]; ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK3 protein]
Chitosan results in increased expression of ARB2A mRNA
CTD PMID:36706893 NCBI chr13:77,856,799...78,314,359
Ensembl chr13:77,850,152...78,314,354
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP
ISO
[Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of BAX protein]
CTD PMID:18567086 PMID:30928397 PMID:38211767 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions EXP
ISO
[Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein
[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of BCL2 protein]; [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]
CTD PMID:18567086 PMID:28732690 PMID:30928397 PMID:38211767 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bglap bone gamma carboxyglutamate protein increases expression ISO Chitosan results in increased expression of BGLAP mRNA CTD PMID:25246786 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Casp2 caspase 2 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]] CTD PMID:38369055 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Chitosan metabolite inhibits the reaction [Copper results in increased activity of CASP3 protein]
Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Chitosan inhibits the reaction [carbendazim results in increased expression of CASP3 protein]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]]
CTD PMID:25542178 PMID:30928397 PMID:35705592 PMID:38369055 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA]] CTD PMID:38369055 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of CASP9 protein] CTD PMID:30928397 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO [Chitosan analog co-treated with Quercetin] inhibits the reaction [ochratoxin A results in decreased activity of CAT protein]; [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Chitosan analog inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Chitosan analog inhibits the reaction [ochratoxin A results in decreased activity of CAT protein]; Chitosan inhibits the reaction [carbendazim results in decreased expression of CAT protein]; Chitosan inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:12679053 PMID:22704994 PMID:27923682 PMID:30928397 PMID:35705592 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Clec7a C-type lectin domain family 7, member a multiple interactions
decreases expression
ISO Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA]
Chitosan results in decreased expression of CLEC7A mRNA
CTD PMID:21329777 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
JBrowse link
G Col15a1 collagen, type XV, alpha 1 decreases expression ISO Chitosan results in decreased expression of COL15A1 mRNA CTD PMID:36706893 NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167
JBrowse link
G Cpe carboxypeptidase E multiple interactions
decreases expression
ISO ARB2A protein affects the reaction [Chitosan results in decreased expression of CPE protein]
Chitosan results in decreased expression of CPE mRNA; Chitosan results in decreased expression of CPE protein
CTD PMID:36706893 NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of CTNNB1 protein] CTD PMID:28732690 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of CYP11A1 mRNA] CTD PMID:38211767 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions ISO Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]; Fish Oils promotes the reaction [Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]] CTD PMID:28987369 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Chitosan results in increased expression of DKK1 mRNA CTD PMID:36706893 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA] CTD PMID:28987369 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA] CTD PMID:28987369 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO Chitosan results in decreased phosphorylation of FOXO3 protein CTD PMID:36706893 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Gcg glucagon increases expression
increases secretion
multiple interactions
ISO Chitosan results in increased expression of GCG mRNA
Chitosan results in increased secretion of GCG protein
SB 203580 inhibits the reaction [Chitosan results in increased expression of GCG mRNA]; SB 203580 inhibits the reaction [Chitosan results in increased secretion of GCG protein]
CTD PMID:23611362 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased secretion of GOT1 protein] CTD PMID:35705592 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased secretion of GPT protein] CTD PMID:35705592 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Chitosan analog co-treated with Quercetin] inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]; [Chitosan analog co-treated with Quercetin] results in increased expression of GPX1 mRNA; Chitosan analog inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]
Chitosan analog results in increased expression of GPX1 mRNA
CTD PMID:27923682 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]] CTD PMID:38369055 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein] CTD PMID:28732690 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gsr glutathione reductase multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of GSR mRNA] CTD PMID:30928397 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA] CTD PMID:28987369 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Chitosan metabolite results in decreased susceptibility to Copper] which results in increased expression of HMOX1 mRNA; [Chitosan metabolite results in decreased susceptibility to Copper] which results in increased expression of HMOX1 protein
Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of HMOX1 mRNA]; Chitosan inhibits the reaction [carbendazim results in decreased expression of HMOX1 mRNA]
CTD PMID:25542178 PMID:30928397 PMID:35705592 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il10 interleukin 10 multiple interactions
increases secretion
ISO Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Chitosan results in increased secretion of IL10 protein
CTD PMID:21329777 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA]] CTD PMID:38369055 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
ISO Chitosan results in increased secretion of IL6 protein
Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:21329777 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK1 protein] CTD PMID:36706893 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of MAPK3 protein]
ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK3 protein]
CTD PMID:28732690 PMID:36706893 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Chitosan inhibits the reaction [Aminolevulinic Acid analog results in increased activity of MMP2 protein] CTD PMID:18806744 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO ARB2A protein affects the reaction [Chitosan results in decreased expression of MMP9 protein]
Chitosan results in decreased expression of MMP9 mRNA; Chitosan results in decreased expression of MMP9 protein
CTD PMID:36706893 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
affects localization
ISO [Chitosan metabolite results in decreased susceptibility to Copper] which results in increased phosphorylation of NFE2L2 protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 mRNA]; Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]; Chitosan inhibits the reaction [carbendazim results in decreased expression of NFE2L2 mRNA]; pyrazolanthrone inhibits the reaction [Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]]; SB 203580 inhibits the reaction [Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]]
Chitosan analog affects the localization of NFE2L2 protein
CTD PMID:25542178 PMID:30928397 PMID:35705592 PMID:38211767 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA]] CTD PMID:38369055 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased expression of NOS2 protein] CTD PMID:35705592 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of NQO1 mRNA] CTD PMID:30928397 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in increased expression of NR1H3 protein] CTD PMID:28987369 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases phosphorylation ISO Chitosan results in decreased phosphorylation of PIK3CA protein CTD PMID:36706893 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases phosphorylation ISO Chitosan results in decreased phosphorylation of PIK3R1 protein CTD PMID:36706893 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:28987369 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Chitosan results in increased expression of PPARGC1A mRNA CTD PMID:36706893 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of RELA protein]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of RELA mRNA]] CTD PMID:28732690 PMID:38369055 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Runx2 runt related transcription factor 2 increases expression ISO Chitosan results in increased expression of RUNX2 mRNA; Chitosan results in increased expression of RUNX2 protein CTD PMID:25246786 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
increases expression
ISO [Chitosan analog co-treated with Quercetin] results in increased expression of SOD1 mRNA; Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of SOD1 mRNA]
Chitosan analog results in increased expression of SOD1 mRNA
CTD PMID:27923682 PMID:30928397 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sparcl1 SPARC-like 1 decreases expression ISO Chitosan results in decreased expression of SPARCL1 mRNA CTD PMID:36706893 NCBI chr 5:104,226,974...104,261,954
Ensembl chr 5:104,226,977...104,261,599
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Chitosan results in increased expression of SPP1 mRNA CTD PMID:25246786 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:28987369 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of STAR mRNA] CTD PMID:38211767 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] CTD PMID:22704994 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
decreases expression
ISO Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR2 mRNA]
Chitosan results in decreased expression of TLR2 mRNA
CTD PMID:21329777 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions
ISO Chitosan results in decreased expression of TLR4 mRNA
Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]
CTD PMID:21329777 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Chitosan results in increased secretion of TNF protein
CTD PMID:21329777 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TPH1 protein] CTD PMID:22704994 NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961
JBrowse link
dextran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 multiple interactions EXP [Dextrans co-treated with ferrite analog] results in increased expression of IL10 mRNA CTD PMID:26576301 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions EXP [Dextrans co-treated with ferrite analog] results in decreased expression of IRAK1 mRNA CTD PMID:26576301 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Probenecid binds to Dextrans] inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] CTD PMID:30102254 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Slc31a2 solute carrier family 31, member 2 decreases uptake EXP SLC31A2 protein results in decreased uptake of Dextrans CTD PMID:20930109 NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b multiple interactions EXP [Dextrans co-treated with ferrite analog] results in decreased expression of TNFRSF1B mRNA CTD PMID:26576301 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
hyaluronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] CTD PMID:19047049 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 increases export
multiple interactions
ISO ABCC5 protein results in increased export of Hyaluronic Acid
[Curcumin analog binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [Curcumin binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [xanthohumol binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; Curcumin analog inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; Curcumin inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; xanthohumol inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]
CTD PMID:23978416 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abra actin-binding Rho activating protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ABRA protein] CTD PMID:23178681 NCBI chr15:41,728,689...41,733,116
Ensembl chr15:41,727,472...41,733,116
JBrowse link
G Acan aggrecan multiple interactions EXP [Hyaluronic Acid co-treated with resveratrol] results in increased expression of ACAN mRNA CTD PMID:23595953 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACAT2 protein]
Hyaluronic Acid analog results in decreased expression of ACAT2 protein
CTD PMID:23178681 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Aco2 aconitase 2, mitochondrial decreases expression ISO Hyaluronic Acid analog results in decreased expression of ACO2 protein CTD PMID:23178681 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:31285260 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actb actin, beta multiple interactions
affects expression
ISO Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide results in decreased expression of ACTB protein]
Hyaluronic Acid analog affects the expression of ACTB protein
CTD PMID:23178681 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTC1 protein] CTD PMID:23178681 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029
JBrowse link
G Actg2 actin, gamma 2, smooth muscle, enteric multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTG2 protein]
Hyaluronic Acid analog results in decreased expression of ACTG2 protein
CTD PMID:23178681 NCBI chr 6:83,489,891...83,513,233
Ensembl chr 6:83,489,887...83,513,247
JBrowse link
G Actr3 ARP3 actin-related protein 3 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTR3 protein] CTD PMID:23178681 NCBI chr 1:125,320,642...125,363,464
Ensembl chr 1:125,320,642...125,363,464
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:23178681 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alb albumin increases abundance ISO ALB protein results in increased abundance of Hyaluronic Acid CTD PMID:16642209 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Anxa1 annexin A1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of ANXA1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA1 protein]
CTD PMID:23178681 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa2 annexin A2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA2 protein] CTD PMID:23178681 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ANXA3 protein CTD PMID:23178681 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
JBrowse link
G Anxa4 annexin A4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA4 protein] CTD PMID:23178681 NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
JBrowse link
G Anxa5 annexin A5 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA5 protein]
Hyaluronic Acid analog results in decreased expression of ANXA5 protein
CTD PMID:23178681 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of ARHGAP29 protein
[Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of ARHGAP29 protein
CTD PMID:23178681 NCBI chr 3:121,746,752...121,810,326
Ensembl chr 3:121,746,190...121,810,402
JBrowse link
G Atg5 autophagy related 5 increases cleavage
multiple interactions
ISO Hyaluronic Acid results in increased cleavage of ATG5 protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased cleavage of ATG5 protein]
CTD PMID:27082295 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of ATIC protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATIC protein]
CTD PMID:23178681 NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP5F1A protein]
Hyaluronic Acid analog results in decreased expression of ATP5F1A protein
CTD PMID:23178681 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Hyaluronic Acid analog results in decreased expression of ATP5F1B protein CTD PMID:23178681 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 increases expression
multiple interactions
ISO Hyaluronic Acid results in increased expression of BNIP3 protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased expression of BNIP3 protein]
CTD PMID:27082295 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Calr calreticulin decreases expression ISO Hyaluronic Acid analog results in decreased expression of CALR protein CTD PMID:23178681 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Calu calumenin decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of CALU protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CALU protein]
CTD PMID:23178681 NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAMK1 protein]
Hyaluronic Acid analog results in decreased expression of CAMK1 protein
CTD PMID:23178681 NCBI chr 6:113,311,085...113,320,883
Ensembl chr 6:113,311,085...113,320,945
JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAR3 protein]
Hyaluronic Acid analog results in decreased expression of CAR3 protein
CTD PMID:23178681 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Casp1 caspase 1 increases cleavage ISO Hyaluronic Acid results in increased cleavage of CASP1 protein CTD PMID:33383130 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA] CTD PMID:17879260 PMID:19047049 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA] CTD PMID:17879260 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP8 protein CTD PMID:20237495 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid] CTD PMID:23692848 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion EXP Hyaluronic Acid analog results in increased secretion of CCL5 protein CTD PMID:9278343 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT2 protein]
Hyaluronic Acid analog results in decreased expression of CCT2 protein
CTD PMID:23178681 NCBI chr10:116,886,902...116,899,757
Ensembl chr10:116,886,906...116,899,719
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT4 protein] CTD PMID:23178681 NCBI chr11:22,940,593...22,953,336
Ensembl chr11:22,940,519...22,953,780
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT5 protein]
Hyaluronic Acid analog results in decreased expression of CCT5 protein
CTD PMID:23178681 NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950
JBrowse link
G Cd44 CD44 antigen multiple interactions
increases expression
affects binding
ISO
EXP
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU protein; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR protein; [Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein; Hyaluronic Acid analog binds to and results in increased activity of CD44 protein; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]
Hyaluronic Acid analog affects the localization of [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog promotes the reaction [MAP3K1 protein binds to CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]
Hyaluronic Acid metabolite results in increased expression of CD44 mRNA; Hyaluronic Acid metabolite results in increased expression of CD44 protein
CTD PMID:9929743 PMID:12402308 PMID:19047049 PMID:20159036 PMID:23692848 More... NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cfl1 cofilin 1, non-muscle multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CFL1 protein]
Hyaluronic Acid analog results in decreased expression of CFL1 protein
CTD PMID:23178681 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO [Diclofenac co-treated with Hyaluronic Acid] results in decreased expression of CFLAR protein CTD PMID:20237495 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases export
multiple interactions
ISO CFTR protein results in increased export of Hyaluronic Acid
Curcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]; xanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]
CTD PMID:23978416 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Cnn3 calponin 3, acidic decreases expression ISO Hyaluronic Acid analog results in decreased expression of CNN3 protein CTD PMID:23178681 NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856
JBrowse link
G Col2a1 collagen, type II, alpha 1 multiple interactions EXP [Hyaluronic Acid co-treated with resveratrol] results in increased expression of COL2A1 mRNA CTD PMID:23595953 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576
JBrowse link
G Cops4 COP9 signalosome subunit 4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of COPS4 protein] CTD PMID:23178681 NCBI chr 5:100,666,223...100,695,668
Ensembl chr 5:100,666,175...100,695,669
JBrowse link
G Coq7 demethyl-Q 7 multiple interactions
increases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] affects the expression of COQ7 protein
Hyaluronic Acid analog results in increased expression of COQ7 protein
CTD PMID:23178681 NCBI chr 7:118,108,881...118,132,529
Ensembl chr 7:118,108,882...118,132,579
JBrowse link
G Cpox coproporphyrinogen oxidase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CPOX protein] CTD PMID:23178681 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Cth cystathionine gamma lyase multiple interactions ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of CTH protein CTD PMID:23178681 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of CXCL8 protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein CTD PMID:25053413 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Hyaluronic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CYP1A1 mRNA] CTD PMID:30856093 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Hyaluronic Acid analog results in decreased expression of DLD protein CTD PMID:23178681 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of DNAJA1 protein CTD PMID:23178681 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Dstn destrin multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of DSTN protein]
Hyaluronic Acid analog results in decreased expression of DSTN protein
CTD PMID:23178681 NCBI chr 2:143,757,251...143,785,244
Ensembl chr 2:143,757,240...143,785,244
JBrowse link
G Eci2 enoyl-Coenzyme A delta isomerase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of ECI2 protein] CTD PMID:23178681 NCBI chr13:35,161,731...35,211,098
Ensembl chr13:35,161,731...35,211,079
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF1G protein] CTD PMID:23178681 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of EEF2 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF2 protein]
CTD PMID:23178681 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases phosphorylation ISO Hyaluronic Acid results in increased phosphorylation of EIF4E protein CTD PMID:16864594 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457
JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression ISO Hyaluronic Acid analog results in decreased expression of ENO1 protein CTD PMID:23178681 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ERP29 protein CTD PMID:23178681 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569
JBrowse link
G Esd esterase D/formylglutathione hydrolase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESD protein] CTD PMID:23178681 NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205
JBrowse link
G Ezr ezrin multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EZR protein] CTD PMID:23178681 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fgf23 fibroblast growth factor 23 increases activity EXP Hyaluronic Acid analog results in increased activity of FGF23 protein CTD PMID:16081635 NCBI chr 6:127,049,865...127,059,257
Ensembl chr 6:127,049,865...127,058,371
JBrowse link
G Fgf7 fibroblast growth factor 7 increases chemical synthesis ISO FGF7 protein results in increased chemical synthesis of Hyaluronic Acid CTD PMID:14506240 NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105
JBrowse link
G Fgg fibrinogen gamma chain increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of FGG protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of FGG protein]
CTD PMID:23178681 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Fkbp4 FK506 binding protein 4 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of FKBP4 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of FKBP4 protein]
CTD PMID:23178681 NCBI chr 6:128,407,066...128,415,619
Ensembl chr 6:128,406,698...128,415,640
JBrowse link
G Fscn1 fascin actin-bundling protein 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of FSCN1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of FSCN1 protein]
CTD PMID:23178681 NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions
increases chemical synthesis
ISO [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 multiple interactions
affects expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of FUBP1 protein
Hyaluronic Acid analog affects the expression of FUBP1 protein
CTD PMID:23178681 NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463
JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 increases phosphorylation ISO Hyaluronic Acid results in increased phosphorylation of GAB1 protein CTD PMID:16864594 NCBI chr 8:81,491,060...81,607,151
Ensembl chr 8:81,491,063...81,607,148
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDI1 protein] CTD PMID:23178681 NCBI chr  X:73,348,618...73,355,473
Ensembl chr  X:73,348,604...73,355,468
JBrowse link
G Glrx3 glutaredoxin 3 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of GLRX3 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GLRX3 protein]
CTD PMID:23178681 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323
JBrowse link
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GNB1 protein] CTD PMID:23178681 NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726
JBrowse link
G Gnb2 guanine nucleotide binding protein (G protein), beta 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GNB2 protein] CTD PMID:23178681 NCBI chr 5:137,526,389...137,533,085
Ensembl chr 5:137,526,389...137,531,772
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble decreases expression ISO Hyaluronic Acid analog results in decreased expression of GOT1 protein CTD PMID:23178681 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gsdmd gasdermin D increases expression
increases cleavage
ISO Hyaluronic Acid results in increased expression of GSDMD mRNA
Hyaluronic Acid results in increased cleavage of GSDMD protein
CTD PMID:33383130 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Gsn gelsolin multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of GSN protein
Hyaluronic Acid analog results in decreased expression of GSN protein
CTD PMID:23178681 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904
JBrowse link
G Gucy2f guanylate cyclase 2f multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GUCY2F protein] CTD PMID:23178681 NCBI chr  X:140,862,282...140,980,399
Ensembl chr  X:140,864,156...140,979,927
JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO Hyaluronic Acid metabolite results in increased expression of HAS1 mRNA; Hyaluronic Acid metabolite results in increased expression of HAS1 protein CTD PMID:31226360 NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467
JBrowse link
G Has2 hyaluronan synthase 2 increases chemical synthesis
affects abundance
multiple interactions
ISO
EXP
HAS2 protein results in increased chemical synthesis of Hyaluronic Acid
HAS2 protein affects the abundance of Hyaluronic Acid
[IL1B protein results in increased expression of HAS2 protein] which results in increased chemical synthesis of Hyaluronic Acid
CTD PMID:11318944 PMID:31285260 NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935
JBrowse link
G Has3 hyaluronan synthase 3 multiple interactions
increases expression
EXP
ISO
[HAS3 protein affects the susceptibility to Carbon Tetrachloride] which affects the abundance of Hyaluronic Acid; HAS3 protein affects the reaction [Carbon Tetrachloride results in increased abundance of Hyaluronic Acid]
Hyaluronic Acid metabolite results in increased expression of HAS3 mRNA; Hyaluronic Acid metabolite results in increased expression of HAS3 protein
CTD PMID:27042213 PMID:31226360 NCBI chr 8:107,596,874...107,609,534
Ensembl chr 8:107,596,874...107,611,198
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression
multiple interactions
ISO Hyaluronic Acid results in increased expression of HIF1A protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased expression of HIF1A protein]
CTD PMID:27082295 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMBS protein]
Hyaluronic Acid analog results in decreased expression of HMBS protein
CTD PMID:23178681 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Hmmr hyaluronan mediated motility receptor (RHAMM) multiple interactions ISO Hyaluronic Acid binds to and results in increased activity of HMMR protein CTD PMID:16864594 NCBI chr11:40,592,215...40,624,290
Ensembl chr11:40,592,222...40,624,249
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of HNRNPA2B1 protein CTD PMID:23178681 NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HNRNPH1 protein]
Hyaluronic Acid analog results in decreased expression of HNRNPH1 protein
CTD PMID:23178681 NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO Hyaluronic Acid analog results in decreased expression of HNRNPK protein CTD PMID:23178681 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSP90AA1 protein] CTD PMID:23178681 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of HSP90B1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSP90B1 protein]
CTD PMID:23178681 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
JBrowse link
G Hspa5 heat shock protein 5 affects expression
multiple interactions
ISO Hyaluronic Acid analog affects the expression of HSPA5 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA5 protein]
CTD PMID:23178681 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA8 protein]
Hyaluronic Acid analog results in decreased expression of HSPA8 protein
CTD PMID:23178681 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspb1 heat shock protein 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of HSPB1 protein CTD PMID:23178681 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression ISO Hyaluronic Acid analog results in decreased expression of HSPD1 protein CTD PMID:23178681 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble decreases expression ISO Hyaluronic Acid analog results in decreased expression of IDH1 protein CTD PMID:23178681 NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial decreases expression ISO Hyaluronic Acid analog results in decreased expression of IDH2 protein CTD PMID:23178681 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDO1 protein]
Hyaluronic Acid analog results in decreased expression of IDO1 protein
CTD PMID:23178681 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025
JBrowse link
G Ifng interferon gamma multiple interactions ISO Hyaluronic Acid inhibits the reaction [Acetaminophen results in increased expression of IFNG protein] CTD PMID:18237725 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il12b interleukin 12b increases secretion EXP Hyaluronic Acid analog results in increased secretion of IL12B protein CTD PMID:9278343 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il1b interleukin 1 beta increases abundance
increases expression
multiple interactions
ISO
EXP
IL1B protein results in increased abundance of Hyaluronic Acid
Hyaluronic Acid results in increased expression of IL1B mRNA
[Hyaluronic Acid co-treated with resveratrol] results in decreased expression of IL1B mRNA
Hyaluronic Acid metabolite results in increased expression of IL1B mRNA; Hyaluronic Acid metabolite results in increased expression of IL1B protein
[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of IL1B protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein; [IL1B protein results in increased expression of HAS2 protein] which results in increased chemical synthesis of Hyaluronic Acid; [Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]; Sulindac inhibits the reaction [IL1B protein results in increased abundance of Hyaluronic Acid]
CTD PMID:11318944 PMID:23595953 PMID:23692848 PMID:25053413 PMID:33383130 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of IL6 protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL6 protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL6 protein CTD PMID:25053413 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression ISO Hyaluronic Acid results in increased expression of IRAK3 protein CTD PMID:15728517 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Hyaluronic Acid] CTD PMID:25561734 NCBI chr14:30,651,137...30,665,246
Ensembl chr14:30,651,137...30,665,246
JBrowse link
G Jun jun proto-oncogene increases phosphorylation ISO Hyaluronic Acid analog results in increased phosphorylation of JUN protein CTD PMID:12402308 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Krt10 keratin 10 multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of KRT10 protein]
Hyaluronic Acid analog results in increased expression of KRT10 protein
CTD PMID:23178681 NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190
JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of LAP3 protein CTD PMID:23178681 NCBI chr 5:45,650,716...45,670,033
Ensembl chr 5:45,650,716...45,670,033
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LDHB protein] CTD PMID:23178681 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of LGALS1 protein
Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide results in decreased expression of LGALS1 protein]
CTD PMID:23178681 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
JBrowse link
G Lmna lamin A multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LMNA protein]
Hyaluronic Acid analog results in increased expression of LMNA protein
CTD PMID:23178681 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263
JBrowse link
G Lrpap1 low density lipoprotein receptor-related protein associated protein 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LRPAP1 protein]
Hyaluronic Acid analog results in decreased expression of LRPAP1 protein
CTD PMID:23178681 NCBI chr 5:35,248,834...35,263,043
Ensembl chr 5:35,248,845...35,263,110
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases cleavage
ISO roxadustat promotes the reaction [Hyaluronic Acid results in increased cleavage of MAP1LC3B protein] CTD PMID:27082295 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 increases phosphorylation ISO Hyaluronic Acid analog results in increased phosphorylation of MAP2K1 protein CTD PMID:12402308 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 increases phosphorylation ISO Hyaluronic Acid analog results in increased phosphorylation of MAP2K2 protein CTD PMID:12402308 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions EXP Hyaluronic Acid analog affects the localization of [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog promotes the reaction [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog results in increased phosphorylation of and results in increased activity of MAP3K1 protein CTD PMID:20159036 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Map3k3 mitogen-activated protein kinase kinase kinase 3 multiple interactions EXP MAP3K3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr11:105,975,358...106,047,482
Ensembl chr11:105,975,439...106,046,272
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Hyaluronic Acid analog results in increased phosphorylation of MAPK1 protein
MAPK1 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; U 0126 inhibits the reaction [Hyaluronic Acid analog results in increased phosphorylation of MAPK1 protein]
CTD PMID:12402308 PMID:20159036 PMID:20633555 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Hyaluronic Acid analog results in increased phosphorylation of MAPK3 protein
MAPK3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; U 0126 inhibits the reaction [Hyaluronic Acid analog results in increased phosphorylation of MAPK3 protein]
CTD PMID:12402308 PMID:20159036 PMID:20633555 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions EXP MAPK7 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232
JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of MFN1 protein CTD PMID:23178681 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
increases expression
EXP [Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP13 mRNA
Hyaluronic Acid metabolite results in increased expression of MMP13 mRNA; Hyaluronic Acid metabolite results in increased expression of MMP13 protein
CTD PMID:23595953 PMID:23692848 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions EXP [Hyaluronic Acid co-treated with Resveratrol] results in decreased expression of MMP1 mRNA CTD PMID:23595953 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 affects activity EXP Hyaluronic Acid affects the activity of MMP2 protein CTD PMID:15597151 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP [Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP3 mRNA CTD PMID:23595953 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects activity EXP Hyaluronic Acid affects the activity of MMP9 protein CTD PMID:15597151 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein] CTD PMID:14697411 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mrps7 mitchondrial ribosomal protein S7 decreases expression ISO Hyaluronic Acid analog results in decreased expression of MRPS7 protein CTD PMID:23178681 NCBI chr11:115,494,966...115,498,862
Ensembl chr11:115,494,751...115,498,862
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MUS81 protein]
Hyaluronic Acid analog results in decreased expression of MUS81 protein
CTD PMID:23178681 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430
JBrowse link
G Myl12a myosin, light chain 12A, regulatory, non-sarcomeric multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MYL12A protein]
Hyaluronic Acid analog results in decreased expression of MYL12A protein
CTD PMID:23178681 NCBI chr17:71,300,788...71,309,528
Ensembl chr17:71,300,651...71,309,873
JBrowse link
G Myl12b myosin, light chain 12B, regulatory decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of MYL12B protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MYL12B protein]
CTD PMID:23178681 NCBI chr17:71,280,958...71,297,511
Ensembl chr17:71,280,128...71,297,885
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP
ISO
Hyaluronic Acid metabolite results in increased activity of [NFKB1 protein binds to RELA protein]
[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein]
CTD PMID:17879260 PMID:23692848 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
decreases phosphorylation
ISO [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein]
Hyaluronic Acid results in decreased phosphorylation of NFKBIA protein
CTD PMID:17879260 PMID:33383130 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Hyaluronic Acid results in increased expression of NLRP3 mRNA; Hyaluronic Acid results in increased expression of NLRP3 protein CTD PMID:33383130 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of NME1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NME1 protein]
CTD PMID:23178681 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NME2 protein]
Hyaluronic Acid analog results in decreased expression of NME2 protein
CTD PMID:23178681 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
JBrowse link
G Nos2 nitric oxide synthase 2, inducible affects expression
increases expression
EXP Hyaluronic Acid affects the expression of NOS2 mRNA
Hyaluronic Acid metabolite results in increased expression of NOS2 mRNA; Hyaluronic Acid metabolite results in increased expression of NOS2 protein
CTD PMID:15597151 PMID:23692848 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO Hyaluronic Acid results in decreased expression of NR1D1 mRNA CTD PMID:17075855 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nrxn1 neurexin I multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRXN1 protein] CTD PMID:23178681 NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499
JBrowse link
G Optn optineurin multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of OPTN protein] CTD PMID:23178681 NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific decreases expression ISO Hyaluronic Acid analog results in decreased expression of PDE4D protein CTD PMID:23178681 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PDIA3 protein CTD PMID:23178681 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PDIA6 protein] CTD PMID:23178681 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGAM1 protein] CTD PMID:23178681 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PGK1 protein CTD PMID:23178681 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305
JBrowse link
G Pgls 6-phosphogluconolactonase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGLS protein] CTD PMID:23178681 NCBI chr 8:72,044,828...72,048,911
Ensembl chr 8:72,044,820...72,053,736
JBrowse link
G Phb1 prohibitin 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHB1 protein] CTD PMID:23178681 NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHGDH protein] CTD PMID:23178681 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha increases phosphorylation ISO Hyaluronic Acid results in increased phosphorylation of PIK3CA protein CTD PMID:16864594 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PITPNA protein] CTD PMID:23178681 NCBI chr11:75,478,889...75,519,630
Ensembl chr11:75,478,923...75,519,630
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU protein CTD PMID:12402308 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR protein CTD PMID:12402308 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Pls3 plastin 3 (T-isoform) multiple interactions
increases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of PLS3 protein
Hyaluronic Acid analog results in increased expression of PLS3 protein
CTD PMID:23178681 NCBI chr  X:74,829,259...74,918,788
Ensembl chr  X:74,829,260...74,918,788
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of PPIA protein
Hyaluronic Acid analog results in decreased expression of PPIA protein
CTD PMID:23178681 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of PPP1CA protein CTD PMID:23178681 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419
JBrowse link
G Prdx1 peroxiredoxin 1 affects expression ISO Hyaluronic Acid analog affects the expression of PRDX1 protein CTD PMID:23178681 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PRDX2 protein CTD PMID:23178681 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
affects expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PRDX6 protein]
Hyaluronic Acid analog affects the expression of PRDX6 protein
CTD PMID:23178681 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789
JBrowse link
G Prph peripherin decreases expression ISO Hyaluronic Acid analog results in decreased expression of PRPH protein CTD PMID:23178681 NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859
JBrowse link
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMB1 protein] CTD PMID:23178681 NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013
JBrowse link
G Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PSMC2 protein] CTD PMID:23178681 NCBI chr 5:21,990,273...22,008,785
Ensembl chr 5:21,990,281...22,008,785
JBrowse link
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMC4 protein]
Hyaluronic Acid analog results in decreased expression of PSMC4 protein
CTD PMID:23178681 NCBI chr 7:27,741,127...27,749,517
Ensembl chr 7:27,741,132...27,749,526
JBrowse link
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PSMC5 protein CTD PMID:23178681 NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of PTK2 protein] CTD PMID:23178681 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RACK1 protein] CTD PMID:23178681 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261
JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RAN protein]
Hyaluronic Acid analog results in decreased expression of RAN protein
CTD PMID:23178681 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases phosphorylation
ISO
EXP
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]
Hyaluronic Acid results in increased phosphorylation of RELA protein
Hyaluronic Acid metabolite results in increased phosphorylation of RELA protein
Hyaluronic Acid metabolite results in increased activity of [NFKB1 protein binds to RELA protein]
CTD PMID:17879260 PMID:19047049 PMID:23692848 PMID:31226360 PMID:33383130 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Renbp renin binding protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RENBP protein] CTD PMID:23178681 NCBI chr  X:72,965,727...72,974,408
Ensembl chr  X:72,965,727...72,974,456
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 increases phosphorylation ISO Hyaluronic Acid results in increased phosphorylation of ROCK1 protein CTD PMID:16864594 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G Rps12 ribosomal protein S12 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RPS12 protein]
Hyaluronic Acid analog results in decreased expression of RPS12 protein
CTD PMID:23178681 NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173
JBrowse link
G Scrn1 secernin 1 multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of SCRN1 protein
Hyaluronic Acid analog results in decreased expression of SCRN1 protein
CTD PMID:23178681 NCBI chr 6:54,451,813...54,543,332
Ensembl chr 6:54,478,158...54,543,474
JBrowse link
G Septin11 septin 11 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SEPTIN11 protein]
Hyaluronic Acid analog results in decreased expression of SEPTIN11 protein
CTD PMID:23178681 NCBI chr 5:93,227,445...93,329,237
Ensembl chr 5:93,241,296...93,324,306
JBrowse link
G Septin2 septin 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of SEPTIN2 protein CTD PMID:23178681 NCBI chr 1:93,406,238...93,437,455
Ensembl chr 1:93,406,686...93,437,982
JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 multiple interactions
affects expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SERPINH1 protein]
Hyaluronic Acid analog affects the expression of SERPINH1 protein
CTD PMID:23178681 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446
JBrowse link
G Slc25a11 solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 decreases expression ISO Hyaluronic Acid analog results in decreased expression of SLC25A11 protein CTD PMID:23178681 NCBI chr11:70,534,845...70,538,356
Ensembl chr11:70,535,022...70,538,305
JBrowse link
G Slmap sarcolemma associated protein decreases expression ISO Hyaluronic Acid analog results in decreased expression of SLMAP protein CTD PMID:23178681 NCBI chr14:26,134,323...26,256,103
Ensembl chr14:26,134,323...26,256,086
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Snai2 snail family zinc finger 2 increases expression EXP Hyaluronic Acid analog results in increased expression of SNAI2 mRNA; Hyaluronic Acid analog results in increased expression of SNAI2 protein CTD PMID:20159036 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Sncb synuclein, beta decreases expression ISO Hyaluronic Acid analog results in decreased expression of SNCB protein CTD PMID:23178681 NCBI chr13:54,906,673...54,914,435
Ensembl chr13:54,906,673...54,914,408
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression ISO Hyaluronic Acid analog results in decreased expression of SOD1 protein CTD PMID:23178681 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod3 superoxide dismutase 3, extracellular affects binding
multiple interactions
EXP SOD3 protein binds to Hyaluronic Acid
SOD3 protein inhibits the reaction [[Copper co-treated with Hydrogen Peroxide] results in increased degradation of Hyaluronic Acid]
CTD PMID:18165226 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SORD protein] CTD PMID:23178681 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 multiple interactions EXP [Hyaluronic Acid co-treated with resveratrol] results in increased expression of SOX9 mRNA CTD PMID:23595953 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of SRC protein] CTD PMID:23178681 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Stam2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of STAM2 protein CTD PMID:23178681 NCBI chr 2:52,582,213...52,632,212
Ensembl chr 2:52,581,676...52,632,293
JBrowse link
G Stip1 stress-induced phosphoprotein 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of STIP1 protein]
Hyaluronic Acid analog results in decreased expression of STIP1 protein
CTD PMID:23178681 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
JBrowse link
G Tcp1 t-complex protein 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TCP1 protein] CTD PMID:23178681 NCBI chr17:13,135,216...13,143,954
Ensembl chr17:13,134,588...13,143,954
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:31285260 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions
increases abundance
EXP MAP3K3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK1 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK7 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tlr2 toll-like receptor 2 increases expression
multiple interactions
EXP Hyaluronic Acid metabolite results in increased expression of TLR2 mRNA; Hyaluronic Acid metabolite results in increased expression of TLR2 protein
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR2 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR2 protein]
CTD PMID:23692848 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
increases abundance
EXP
ISO
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 protein]
Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA; Hyaluronic Acid metabolite results in increased expression of TLR4 protein
TLR4 protein results in increased abundance of Hyaluronic Acid
[Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]
CTD PMID:23692848 PMID:25053413 PMID:31226360 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
increases expression
ISO
EXP
[Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of TNF protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of TNF protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of TNF protein
TNF mRNA results in increased abundance of Hyaluronic Acid
Hyaluronic Acid metabolite results in increased expression of TNF mRNA; Hyaluronic Acid metabolite results in increased expression of TNF protein
CTD PMID:14697411 PMID:23692848 PMID:25053413 PMID:25106431 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 affects binding
multiple interactions
ISO TNFAIP6 protein modified form binds to Hyaluronic Acid
TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Hyaluronic Acid]
CTD PMID:12401803 PMID:25561734 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
G Tpm2 tropomyosin 2, beta multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TPM2 protein] CTD PMID:23178681 NCBI chr 4:43,513,726...43,523,583
Ensembl chr 4:43,514,711...43,523,765
JBrowse link
G Tpm3 tropomyosin 3, gamma multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TPM3 protein]
Hyaluronic Acid analog results in decreased expression of TPM3 protein
CTD PMID:23178681 NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of TPT1 protein CTD PMID:23178681 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965
JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TUBB5 protein] CTD PMID:23178681 NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198
JBrowse link
G Vcp valosin containing protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of VCP protein] CTD PMID:23178681 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Hyaluronic Acid promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein] CTD PMID:20067761 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vim vimentin increases expression
multiple interactions
affects expression
EXP
ISO
Hyaluronic Acid analog results in increased expression of VIM protein
Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide affects the expression of VIM protein]
Hyaluronic Acid analog affects the expression of VIM protein
CTD PMID:20159036 PMID:23178681 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Vps33a VPS33A CORVET/HOPS core subunit multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of VPS33A protein]
Hyaluronic Acid analog results in increased expression of VPS33A protein
CTD PMID:23178681 NCBI chr 5:123,666,820...123,711,104
Ensembl chr 5:123,666,722...123,711,101
JBrowse link
G Wdr1 WD repeat domain 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of WDR1 protein] CTD PMID:23178681 NCBI chr 5:38,684,149...38,720,265
Ensembl chr 5:38,684,156...38,720,564
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of YARS1 protein] CTD PMID:23178681 NCBI chr 4:129,083,595...129,113,033
Ensembl chr 4:129,083,553...129,113,400
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22252
    chemical entity 22251
      molecular entity 22244
        polyatomic entity 22094
          macromolecule 9335
            biomacromolecule 8851
              exopolysaccharide 261
                (1->3)-beta-D-glucan + 1
                alginic acid 24
                amorphous cellulose 0
                chitosan 62
                crystalline cellulose 0
                dextran 5
                galactosaminogalactan 0
                galactoxylomannan 0
                hyaluronic acid 203
                indican 0
                mucilage 0
                pullulan 0
                schizophyllan 0
                succinoglucan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22252
    subatomic particle 22245
      composite particle 22245
        hadron 22245
          baryon 22245
            nucleon 22245
              atomic nucleus 22245
                atom 22245
                  main group element atom 22121
                    p-block element atom 22121
                      carbon group element atom 21917
                        carbon atom 21857
                          organic molecular entity 21857
                            biomacromolecule 8851
                              exopolysaccharide 261
                                (1->3)-beta-D-glucan + 1
                                alginic acid 24
                                amorphous cellulose 0
                                chitosan 62
                                crystalline cellulose 0
                                dextran 5
                                galactosaminogalactan 0
                                galactoxylomannan 0
                                hyaluronic acid 203
                                indican 0
                                mucilage 0
                                pullulan 0
                                schizophyllan 0
                                succinoglucan 0
paths to the root