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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:exopolysaccharide
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Accession:CHEBI:72813 term browser browse the term
Definition:A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.
Synonyms:related_synonym: exopolysaccharides;   extracellular polymeric substance;   extracellular polymeric substances
 xref: MetaCyc:Exopolysaccharides;   PMID:11160795;   PMID:11785425;   PMID:1444258;   PMID:15738217;   PMID:16075348;   PMID:17440912;   PMID:18097339;   PMID:19453747;   PMID:20172021;   PMID:20631870;   PMID:20718297;   PMID:2688547;   PMID:6354590;   Wikipedia:Exopolysaccharide;   Wikipedia:Extracellular_polymeric_substance



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(1->3)-beta-D-glucan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSLP thymic stromal lymphopoietin increases expression EXP (1->3)-beta-D-glucan increases expression of TSLP mRNA and protein in corneal epithelial cells RGD PMID:26874828 RGD:38549373 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
JBrowse link
alginic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAN aggrecan increases expression EXP alginic acid results in increased expression of ACAN mRNA CTD PMID:16371897 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353
JBrowse link
G ATG12 autophagy related 12 increases expression ISO Alginic Acid results in increased expression of ATG12 protein CTD PMID:35066102 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATG7 autophagy related 7 increases expression ISO Alginic Acid results in increased expression of ATG7 protein CTD PMID:35066102 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression ISO Alginic Acid results in decreased expression of BCL2 protein CTD PMID:35066102 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression ISO Alginic Acid results in decreased expression of BCL2L1 protein CTD PMID:35066102 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BECN1 beclin 1 increases expression ISO Alginic Acid results in increased expression of BECN1 protein CTD PMID:35066102 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CASP3 caspase 3 increases expression
increases cleavage
ISO Alginic Acid results in increased expression of CASP3 protein
Alginic Acid results in increased cleavage of CASP3 protein
CTD PMID:35066102 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:35066102 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases expression ISO Alginic Acid results in increased expression of CASP9 protein CTD PMID:35066102 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression ISO Alginic Acid results in decreased expression of CAT protein CTD PMID:35066102 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G COL10A1 collagen type X alpha 1 chain increases expression EXP alginic acid results in increased expression of COL10A1 mRNA CTD PMID:16371897 NCBI chr 6:116,118,909...116,217,144
Ensembl chr 6:116,118,909...116,158,747
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 increases expression ISO Alginic Acid results in increased expression of CYP17A1 protein CTD PMID:35066102 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases expression ISO Alginic Acid results in decreased expression of CYP19A1 protein CTD PMID:35066102 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G FSHR follicle stimulating hormone receptor decreases expression ISO Alginic Acid results in decreased expression of FSHR protein CTD PMID:35066102 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
G GPX5 glutathione peroxidase 5 decreases expression ISO Alginic Acid results in decreased expression of GPX5 protein CTD PMID:35066102 NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases lipidation ISO Alginic Acid results in increased lipidation of MAP1LC3B protein CTD PMID:35066102 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:35066102 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G RAB7A RAB7A, member RAS oncogene family increases expression ISO Alginic Acid results in increased expression of RAB7 protein CTD PMID:35066102 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression ISO Alginic Acid results in decreased expression of SOD1 protein CTD PMID:35066102 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression ISO Alginic Acid results in decreased expression of SOD2 protein CTD PMID:35066102 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SQSTM1 sequestosome 1 decreases expression ISO Alginic Acid results in decreased expression of SQSTM1 protein CTD PMID:35066102 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G STAR steroidogenic acute regulatory protein decreases expression ISO Alginic Acid results in decreased expression of STAR protein CTD PMID:35066102 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP alginic acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; alginic acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
chitosan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of ABCA1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in decreased expression of ABCA1 mRNA] CTD PMID:28987369 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of AKT1 protein]
Chitosan results in decreased phosphorylation of AKT1 protein
CTD PMID:28732690 PMID:36706893 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of ALAD protein] CTD PMID:22704994 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated increases expression EXP Chitosan results in increased expression of ALPL mRNA; Chitosan results in increased expression of ALPL protein CTD PMID:25246786 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G AOX1 aldehyde oxidase 1 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of AOX1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in decreased expression of AOX1 mRNA] CTD PMID:28987369 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064
JBrowse link
G ARB2A ARB2 cotranscriptional regulator A multiple interactions
increases expression
EXP ARB2A protein affects the reaction [Chitosan results in decreased expression of CPE protein]; ARB2A protein affects the reaction [Chitosan results in decreased expression of MMP9 protein]; ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK1 protein]; ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK3 protein]
Chitosan results in increased expression of ARB2A mRNA
CTD PMID:36706893 NCBI chr 5:93,617,725...94,111,699
Ensembl chr 5:93,617,725...94,111,699
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of BAX protein]
CTD PMID:18567086 PMID:30928397 PMID:38211767 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein
[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of BCL2 protein]; [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]
CTD PMID:18567086 PMID:28732690 PMID:30928397 PMID:38211767 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression EXP Chitosan results in increased expression of BGLAP mRNA CTD PMID:25246786 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G CASP2 caspase 2 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]] CTD PMID:38369055 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP3 caspase 3 multiple interactions EXP
ISO
Chitosan metabolite inhibits the reaction [Copper results in increased activity of CASP3 protein]
Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Chitosan inhibits the reaction [carbendazim results in increased expression of CASP3 protein]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]]
CTD PMID:25542178 PMID:30928397 PMID:35705592 PMID:38369055 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA]] CTD PMID:38369055 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP9 caspase 9 multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in increased expression of CASP9 protein] CTD PMID:30928397 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions ISO [Chitosan analog co-treated with Quercetin] inhibits the reaction [ochratoxin A results in decreased activity of CAT protein]; [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Chitosan analog inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Chitosan analog inhibits the reaction [ochratoxin A results in decreased activity of CAT protein]; Chitosan inhibits the reaction [carbendazim results in decreased expression of CAT protein]; Chitosan inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:12679053 PMID:22704994 PMID:27923682 PMID:30928397 PMID:35705592 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CLEC7A C-type lectin domain containing 7A multiple interactions
decreases expression
EXP Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA]
Chitosan results in decreased expression of CLEC7A mRNA
CTD PMID:21329777 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
JBrowse link
G COL15A1 collagen type XV alpha 1 chain decreases expression EXP Chitosan results in decreased expression of COL15A1 mRNA CTD PMID:36706893 NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787
JBrowse link
G CPE carboxypeptidase E multiple interactions
decreases expression
EXP ARB2A protein affects the reaction [Chitosan results in decreased expression of CPE protein]
Chitosan results in decreased expression of CPE mRNA; Chitosan results in decreased expression of CPE protein
CTD PMID:36706893 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of CTNNB1 protein] CTD PMID:28732690 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of CYP11A1 mRNA] CTD PMID:38211767 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases activity EXP Chitosan analog results in increased activity of CYP3A4 protein CTD PMID:20831879 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]; Fish Oils promotes the reaction [Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]] CTD PMID:28987369 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 increases expression EXP Chitosan results in increased expression of DKK1 mRNA CTD PMID:36706893 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G FABP4 fatty acid binding protein 4 multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA] CTD PMID:28987369 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G FASN fatty acid synthase multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA] CTD PMID:28987369 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FOXO3 forkhead box O3 decreases phosphorylation EXP Chitosan results in decreased phosphorylation of FOXO3 protein CTD PMID:36706893 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G GCG glucagon increases expression
increases secretion
multiple interactions
EXP Chitosan results in increased expression of GCG mRNA
Chitosan results in increased secretion of GCG protein
SB 203580 inhibits the reaction [Chitosan results in increased expression of GCG mRNA]; SB 203580 inhibits the reaction [Chitosan results in increased secretion of GCG protein]
CTD PMID:23611362 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased secretion of GOT1 protein] CTD PMID:35705592 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased secretion of GPT protein] CTD PMID:35705592 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Chitosan analog co-treated with Quercetin] inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]; [Chitosan analog co-treated with Quercetin] results in increased expression of GPX1 mRNA; Chitosan analog inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA]
Chitosan analog results in increased expression of GPX1 mRNA
CTD PMID:27923682 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GSDMD gasdermin D multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]] CTD PMID:38369055 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein] CTD PMID:28732690 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of GSR mRNA] CTD PMID:30928397 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA] CTD PMID:28987369 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP
ISO
[Chitosan metabolite results in decreased susceptibility to Copper] which results in increased expression of HMOX1 mRNA; [Chitosan metabolite results in decreased susceptibility to Copper] which results in increased expression of HMOX1 protein
Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of HMOX1 mRNA]; Chitosan inhibits the reaction [carbendazim results in decreased expression of HMOX1 mRNA]
CTD PMID:25542178 PMID:30928397 PMID:35705592 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IL10 interleukin 10 multiple interactions
increases secretion
EXP Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Chitosan results in increased secretion of IL10 protein
CTD PMID:21329777 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA]] CTD PMID:38369055 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 increases secretion
multiple interactions
EXP Chitosan results in increased secretion of IL6 protein
Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:21329777 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
multiple interactions
EXP Chitosan results in decreased phosphorylation of MAPK1 protein
ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK1 protein]
CTD PMID:36706893 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of MAPK3 protein]
Chitosan results in decreased phosphorylation of MAPK3 protein
ARB2A protein affects the reaction [Chitosan results in decreased phosphorylation of MAPK3 protein]
CTD PMID:28732690 PMID:36706893 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO Chitosan inhibits the reaction [Aminolevulinic Acid analog results in increased activity of MMP2 protein] CTD PMID:18806744 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
multiple interactions
EXP Chitosan results in decreased expression of MMP9 mRNA; Chitosan results in decreased expression of MMP9 protein
ARB2A protein affects the reaction [Chitosan results in decreased expression of MMP9 protein]
CTD PMID:36706893 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
EXP
ISO
[Chitosan metabolite results in decreased susceptibility to Copper] which results in increased phosphorylation of NFE2L2 protein
Chitosan analog affects the localization of NFE2L2 protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 mRNA]; Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]; Chitosan inhibits the reaction [carbendazim results in decreased expression of NFE2L2 mRNA]; pyrazolanthrone inhibits the reaction [Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]]; SB 203580 inhibits the reaction [Chitosan analog inhibits the reaction [Doxorubicin affects the localization of NFE2L2 protein]]
CTD PMID:25542178 PMID:30928397 PMID:35705592 PMID:38211767 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA]] CTD PMID:38369055 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Chitosan inhibits the reaction [carbendazim results in increased expression of NOS2 protein] CTD PMID:35705592 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of NQO1 mRNA] CTD PMID:30928397 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in increased expression of NR1H3 protein] CTD PMID:28987369 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases phosphorylation EXP Chitosan results in decreased phosphorylation of PIK3CA protein CTD PMID:36706893 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 decreases phosphorylation EXP Chitosan results in decreased phosphorylation of PIK3R1 protein CTD PMID:36706893 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO [Chitosan co-treated with Fish Oils] inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:28987369 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression EXP Chitosan results in increased expression of PPARGC1A mRNA CTD PMID:36706893 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of RELA protein]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of RELA mRNA]] CTD PMID:28732690 PMID:38369055 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression EXP Chitosan results in increased expression of RUNX2 mRNA; Chitosan results in increased expression of RUNX2 protein CTD PMID:25246786 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SOD1 superoxide dismutase 1 increases expression
multiple interactions
ISO Chitosan analog results in increased expression of SOD1 mRNA
[Chitosan analog co-treated with Quercetin] results in increased expression of SOD1 mRNA; Chitosan analog inhibits the reaction [Doxorubicin results in decreased expression of SOD1 mRNA]
CTD PMID:27923682 PMID:30928397 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SPARCL1 SPARC like 1 decreases expression EXP Chitosan results in decreased expression of SPARCL1 mRNA CTD PMID:36706893 NCBI chr 4:87,473,335...87,529,376
Ensembl chr 4:87,473,335...87,531,061
JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression EXP Chitosan results in increased expression of SPP1 mRNA CTD PMID:25246786 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; Chitosan inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:28987369 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of STAR mRNA] CTD PMID:38211767 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] CTD PMID:22704994 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G TLR2 toll like receptor 2 multiple interactions
decreases expression
EXP Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR2 mRNA]
Chitosan results in decreased expression of TLR2 mRNA
CTD PMID:21329777 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260
JBrowse link
G TLR4 toll like receptor 4 decreases expression
multiple interactions
EXP Chitosan results in decreased expression of TLR4 mRNA
Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]
CTD PMID:21329777 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases secretion
EXP Chitosan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Chitosan results in increased secretion of TNF protein
CTD PMID:21329777 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TPH1 tryptophan hydroxylase 1 multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TPH1 protein] CTD PMID:22704994 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,555...18,046,269
JBrowse link
dextran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 multiple interactions ISO [Dextrans co-treated with ferrite analog] results in increased expression of IL10 mRNA CTD PMID:26576301 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 multiple interactions ISO [Dextrans co-treated with ferrite analog] results in decreased expression of IRAK1 mRNA CTD PMID:26576301 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G MPO myeloperoxidase multiple interactions ISO [Probenecid binds to Dextrans] inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] CTD PMID:30102254 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G SLC31A2 solute carrier family 31 member 2 decreases uptake ISO SLC31A2 protein results in decreased uptake of Dextrans CTD PMID:20930109 NCBI chr 9:113,151,007...113,164,140
Ensembl chr 9:113,150,976...113,164,140
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions ISO [Dextrans co-treated with ferrite analog] results in decreased expression of TNFRSF1B mRNA CTD PMID:26576301 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
hyaluronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] CTD PMID:19047049 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 increases export
multiple interactions
EXP ABCC5 protein results in increased export of Hyaluronic Acid
[Curcumin analog binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [Curcumin binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [xanthohumol binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; Curcumin analog inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; Curcumin inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; xanthohumol inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]
CTD PMID:23978416 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939
JBrowse link
G ABRA actin binding Rho activating protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ABRA protein] CTD PMID:23178681 NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244
JBrowse link
G ACAN aggrecan multiple interactions ISO [Hyaluronic Acid co-treated with resveratrol] results in increased expression of ACAN mRNA CTD PMID:23595953 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACAT2 protein]
Hyaluronic Acid analog results in decreased expression of ACAT2 protein
CTD PMID:23178681 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
JBrowse link
G ACO2 aconitase 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ACO2 protein CTD PMID:23178681 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:31285260 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ACTB actin beta multiple interactions
affects expression
ISO Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide results in decreased expression of ACTB protein]
Hyaluronic Acid analog affects the expression of ACTB protein
CTD PMID:23178681 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTC1 protein] CTD PMID:23178681 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589
JBrowse link
G ACTG2 actin gamma 2, smooth muscle multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTG2 protein]
Hyaluronic Acid analog results in decreased expression of ACTG2 protein
CTD PMID:23178681 NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865
JBrowse link
G ACTR3 actin related protein 3 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ACTR3 protein] CTD PMID:23178681 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:23178681 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALB albumin increases abundance EXP ALB protein results in increased abundance of Hyaluronic Acid CTD PMID:16642209 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ANXA1 annexin A1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of ANXA1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA1 protein]
CTD PMID:23178681 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629
JBrowse link
G ANXA2 annexin A2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA2 protein] CTD PMID:23178681 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G ANXA3 annexin A3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ANXA3 protein CTD PMID:23178681 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
JBrowse link
G ANXA4 annexin A4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA4 protein] CTD PMID:23178681 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
JBrowse link
G ANXA5 annexin A5 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA5 protein]
Hyaluronic Acid analog results in decreased expression of ANXA5 protein
CTD PMID:23178681 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of ARHGAP29 protein
[Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of ARHGAP29 protein
CTD PMID:23178681 NCBI chr 1:94,168,905...94,314,592
Ensembl chr 1:94,148,988...94,275,068
JBrowse link
G ATG5 autophagy related 5 increases cleavage
multiple interactions
ISO Hyaluronic Acid results in increased cleavage of ATG5 protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased cleavage of ATG5 protein]
CTD PMID:27082295 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of ATIC protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATIC protein]
CTD PMID:23178681 NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773
JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP5F1A protein]
Hyaluronic Acid analog results in decreased expression of ATP5F1A protein
CTD PMID:23178681 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta decreases expression ISO Hyaluronic Acid analog results in decreased expression of ATP5F1B protein CTD PMID:23178681 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO Hyaluronic Acid results in increased expression of BNIP3 protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased expression of BNIP3 protein]
CTD PMID:27082295 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAR3 protein]
Hyaluronic Acid analog results in decreased expression of CAR3 protein
CTD PMID:23178681 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
JBrowse link
G CALR calreticulin decreases expression ISO Hyaluronic Acid analog results in decreased expression of CALR protein CTD PMID:23178681 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CALU calumenin decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of CALU protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CALU protein]
CTD PMID:23178681 NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400
JBrowse link
G CAMK1 calcium/calmodulin dependent protein kinase I multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAMK1 protein]
Hyaluronic Acid analog results in decreased expression of CAMK1 protein
CTD PMID:23178681 NCBI chr 3:9,757,347...9,769,947
Ensembl chr 3:9,757,347...9,769,992
JBrowse link
G CASP1 caspase 1 increases cleavage ISO Hyaluronic Acid results in increased cleavage of CASP1 protein CTD PMID:33383130 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP10 caspase 10 multiple interactions EXP [Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP10 protein CTD PMID:20237495 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428
JBrowse link
G CASP3 caspase 3 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA] CTD PMID:17879260 PMID:19047049 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 multiple interactions EXP [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA] CTD PMID:17879260 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 multiple interactions EXP [Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP8 protein CTD PMID:20237495 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CAT catalase multiple interactions ISO CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid] CTD PMID:23692848 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases secretion ISO Hyaluronic Acid analog results in increased secretion of CCL5 protein CTD PMID:9278343 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT2 protein]
Hyaluronic Acid analog results in decreased expression of CCT2 protein
CTD PMID:23178681 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT4 protein] CTD PMID:23178681 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCT5 protein]
Hyaluronic Acid analog results in decreased expression of CCT5 protein
CTD PMID:23178681 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CD44 CD44 molecule (IN blood group) multiple interactions
increases expression
affects binding
EXP
ISO
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU protein; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR protein; [Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein; Hyaluronic Acid analog binds to and results in increased activity of CD44 protein; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]
Hyaluronic Acid analog affects the localization of [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog promotes the reaction [MAP3K1 protein binds to CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]
Hyaluronic Acid metabolite results in increased expression of CD44 mRNA; Hyaluronic Acid metabolite results in increased expression of CD44 protein
CTD PMID:9929743 PMID:12402308 PMID:19047049 PMID:20159036 PMID:23692848 More... NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CFL1 cofilin 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CFL1 protein]
Hyaluronic Acid analog results in decreased expression of CFL1 protein
CTD PMID:23178681 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator multiple interactions EXP [Diclofenac co-treated with Hyaluronic Acid] results in decreased expression of CFLAR protein CTD PMID:20237495 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CFTR CF transmembrane conductance regulator increases export
multiple interactions
EXP CFTR protein results in increased export of Hyaluronic Acid
Curcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]; xanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]
CTD PMID:23978416 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CNN3 calponin 3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of CNN3 protein CTD PMID:23178681 NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223
JBrowse link
G COL2A1 collagen type II alpha 1 chain multiple interactions ISO [Hyaluronic Acid co-treated with resveratrol] results in increased expression of COL2A1 mRNA CTD PMID:23595953 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
JBrowse link
G COPS4 COP9 signalosome subunit 4 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of COPS4 protein] CTD PMID:23178681 NCBI chr 4:83,035,183...83,075,818
Ensembl chr 4:83,034,447...83,075,818
JBrowse link
G COQ7 coenzyme Q7, hydroxylase multiple interactions
increases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] affects the expression of COQ7 protein
Hyaluronic Acid analog results in increased expression of COQ7 protein
CTD PMID:23178681 NCBI chr16:19,067,614...19,083,097
Ensembl chr16:19,067,614...19,080,095
JBrowse link
G CPOX coproporphyrinogen oxidase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of CPOX protein] CTD PMID:23178681 NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648
JBrowse link
G CTH cystathionine gamma-lyase multiple interactions ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of CTH protein CTD PMID:23178681 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of CXCL8 protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein CTD PMID:25053413 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP Hyaluronic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CYP1A1 mRNA] CTD PMID:30856093 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DLD dihydrolipoamide dehydrogenase decreases expression ISO Hyaluronic Acid analog results in decreased expression of DLD protein CTD PMID:23178681 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of DNAJA1 protein CTD PMID:23178681 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
JBrowse link
G DSTN destrin, actin depolymerizing factor multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of DSTN protein]
Hyaluronic Acid analog results in decreased expression of DSTN protein
CTD PMID:23178681 NCBI chr20:17,570,075...17,609,919
Ensembl chr20:17,570,075...17,609,919
JBrowse link
G ECI2 enoyl-CoA delta isomerase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of ECI2 protein] CTD PMID:23178681 NCBI chr 6:4,115,706...4,135,575
Ensembl chr 6:4,115,693...4,135,597
JBrowse link
G EEF1G eukaryotic translation elongation factor 1 gamma multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF1G protein] CTD PMID:23178681 NCBI chr11:62,559,596...62,573,891
Ensembl chr11:62,559,596...62,574,086
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of EEF2 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF2 protein]
CTD PMID:23178681 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EIF4E eukaryotic translation initiation factor 4E increases phosphorylation EXP Hyaluronic Acid results in increased phosphorylation of EIF4E protein CTD PMID:16864594 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
JBrowse link
G ENO1 enolase 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ENO1 protein CTD PMID:23178681 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] CTD PMID:19047049 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
JBrowse link
G ERP29 endoplasmic reticulum protein 29 decreases expression ISO Hyaluronic Acid analog results in decreased expression of ERP29 protein CTD PMID:23178681 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449
JBrowse link
G ESD esterase D multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESD protein] CTD PMID:23178681 NCBI chr13:46,771,256...46,797,700
Ensembl chr13:46,771,256...46,797,420
JBrowse link
G EZR ezrin multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EZR protein] CTD PMID:23178681 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G FGF23 fibroblast growth factor 23 increases activity ISO Hyaluronic Acid analog results in increased activity of FGF23 protein CTD PMID:16081635 NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
JBrowse link
G FGF7 fibroblast growth factor 7 increases chemical synthesis ISO FGF7 protein results in increased chemical synthesis of Hyaluronic Acid CTD PMID:14506240 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775
JBrowse link
G FGG fibrinogen gamma chain increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of FGG protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of FGG protein]
CTD PMID:23178681 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G FKBP4 FKBP prolyl isomerase 4 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of FKBP4 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of FKBP4 protein]
CTD PMID:23178681 NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
JBrowse link
G FSCN1 fascin actin-bundling protein 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of FSCN1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of FSCN1 protein]
CTD PMID:23178681 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions
increases chemical synthesis
EXP [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
JBrowse link
G FUBP1 far upstream element binding protein 1 multiple interactions
affects expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of FUBP1 protein
Hyaluronic Acid analog affects the expression of FUBP1 protein
CTD PMID:23178681 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110
JBrowse link
G GAB1 GRB2 associated binding protein 1 increases phosphorylation EXP Hyaluronic Acid results in increased phosphorylation of GAB1 protein CTD PMID:16864594 NCBI chr 4:143,336,876...143,474,565
Ensembl chr 4:143,336,876...143,474,565
JBrowse link
G GDI1 GDP dissociation inhibitor 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDI1 protein] CTD PMID:23178681 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467
JBrowse link
G GLRX3 glutaredoxin 3 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of GLRX3 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GLRX3 protein]
CTD PMID:23178681 NCBI chr10:130,136,391...130,180,377
Ensembl chr10:130,136,391...130,184,521
JBrowse link
G GNB1 G protein subunit beta 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GNB1 protein] CTD PMID:23178681 NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
JBrowse link
G GNB2 G protein subunit beta 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GNB2 protein] CTD PMID:23178681 NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of GOT1 protein CTD PMID:23178681 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GSDMD gasdermin D increases cleavage
increases expression
ISO Hyaluronic Acid results in increased cleavage of GSDMD protein
Hyaluronic Acid results in increased expression of GSDMD mRNA
CTD PMID:33383130 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
JBrowse link
G GSN gelsolin multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of GSN protein
Hyaluronic Acid analog results in decreased expression of GSN protein
CTD PMID:23178681 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G GUCY2F guanylate cyclase 2F, retinal multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of GUCY2F protein] CTD PMID:23178681 NCBI chr  X:109,372,906...109,482,086
Ensembl chr  X:109,372,906...109,482,086
JBrowse link
G HAS1 hyaluronan synthase 1 increases expression EXP Hyaluronic Acid metabolite results in increased expression of HAS1 mRNA; Hyaluronic Acid metabolite results in increased expression of HAS1 protein CTD PMID:31226360 NCBI chr19:51,713,112...51,723,991
Ensembl chr19:51,713,112...51,723,991
JBrowse link
G HAS2 hyaluronan synthase 2 increases chemical synthesis
affects abundance
multiple interactions
EXP
ISO
HAS2 protein results in increased chemical synthesis of Hyaluronic Acid
HAS2 protein affects the abundance of Hyaluronic Acid
[IL1B protein results in increased expression of HAS2 protein] which results in increased chemical synthesis of Hyaluronic Acid
CTD PMID:11318944 PMID:31285260 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440
JBrowse link
G HAS3 hyaluronan synthase 3 multiple interactions
increases expression
ISO
EXP
[HAS3 protein affects the susceptibility to Carbon Tetrachloride] which affects the abundance of Hyaluronic Acid; HAS3 protein affects the reaction [Carbon Tetrachloride results in increased abundance of Hyaluronic Acid]
Hyaluronic Acid metabolite results in increased expression of HAS3 mRNA; Hyaluronic Acid metabolite results in increased expression of HAS3 protein
CTD PMID:27042213 PMID:31226360 NCBI chr16:69,083,484...69,118,719
Ensembl chr16:69,105,653...69,118,719
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO Hyaluronic Acid results in increased expression of HIF1A protein
roxadustat promotes the reaction [Hyaluronic Acid results in increased expression of HIF1A protein]
CTD PMID:27082295 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMBS hydroxymethylbilane synthase multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMBS protein]
Hyaluronic Acid analog results in decreased expression of HMBS protein
CTD PMID:23178681 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
JBrowse link
G HMMR hyaluronan mediated motility receptor multiple interactions EXP Hyaluronic Acid binds to and results in increased activity of HMMR protein CTD PMID:16864594 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of HNRNPA2B1 protein CTD PMID:23178681 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529
JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HNRNPH1 protein]
Hyaluronic Acid analog results in decreased expression of HNRNPH1 protein
CTD PMID:23178681 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K decreases expression ISO Hyaluronic Acid analog results in decreased expression of HNRNPK protein CTD PMID:23178681 NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSP90AA1 protein] CTD PMID:23178681 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of HSP90B1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSP90B1 protein]
CTD PMID:23178681 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 affects expression
multiple interactions
ISO Hyaluronic Acid analog affects the expression of HSPA5 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA5 protein]
CTD PMID:23178681 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA8 protein]
Hyaluronic Acid analog results in decreased expression of HSPA8 protein
CTD PMID:23178681 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of HSPB1 protein CTD PMID:23178681 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of HSPD1 protein CTD PMID:23178681 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of IDH1 protein CTD PMID:23178681 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of IDH2 protein CTD PMID:23178681 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDO1 protein]
Hyaluronic Acid analog results in decreased expression of IDO1 protein
CTD PMID:23178681 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IFNG interferon gamma multiple interactions ISO Hyaluronic Acid inhibits the reaction [Acetaminophen results in increased expression of IFNG protein] CTD PMID:18237725 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL12B interleukin 12B increases secretion ISO Hyaluronic Acid analog results in increased secretion of IL12B protein CTD PMID:9278343 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL1B interleukin 1 beta increases abundance
increases expression
multiple interactions
EXP
ISO
IL1B protein results in increased abundance of Hyaluronic Acid
Hyaluronic Acid results in increased expression of IL1B mRNA
[Hyaluronic Acid co-treated with resveratrol] results in decreased expression of IL1B mRNA
Hyaluronic Acid metabolite results in increased expression of IL1B mRNA; Hyaluronic Acid metabolite results in increased expression of IL1B protein
[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of IL1B protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein; [IL1B protein results in increased expression of HAS2 protein] which results in increased chemical synthesis of Hyaluronic Acid; [Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]; Sulindac inhibits the reaction [IL1B protein results in increased abundance of Hyaluronic Acid]
CTD PMID:11318944 PMID:23595953 PMID:23692848 PMID:25053413 PMID:33383130 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions EXP [acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of IL6 protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL6 protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL6 protein CTD PMID:25053413 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 increases expression EXP Hyaluronic Acid results in increased expression of IRAK3 protein CTD PMID:15728517 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 multiple interactions EXP TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Hyaluronic Acid] CTD PMID:25561734 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP Hyaluronic Acid analog results in increased phosphorylation of JUN protein CTD PMID:12402308 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KRT10 keratin 10 multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of KRT10 protein]
Hyaluronic Acid analog results in increased expression of KRT10 protein
CTD PMID:23178681 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614
JBrowse link
G LAP3 leucine aminopeptidase 3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of LAP3 protein CTD PMID:23178681 NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972
JBrowse link
G LDHB lactate dehydrogenase B multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LDHB protein] CTD PMID:23178681 NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857
JBrowse link
G LGALS1 galectin 1 increases expression
multiple interactions
ISO Hyaluronic Acid analog results in increased expression of LGALS1 protein
Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide results in decreased expression of LGALS1 protein]
CTD PMID:23178681 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G LMNA lamin A/C multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LMNA protein]
Hyaluronic Acid analog results in increased expression of LMNA protein
CTD PMID:23178681 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,572...156,140,081
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of LRPAP1 protein]
Hyaluronic Acid analog results in decreased expression of LRPAP1 protein
CTD PMID:23178681 NCBI chr 4:3,503,612...3,532,422
Ensembl chr 4:3,503,612...3,532,446
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases cleavage
ISO roxadustat promotes the reaction [Hyaluronic Acid results in increased cleavage of MAP1LC3B protein] CTD PMID:27082295 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 increases phosphorylation EXP Hyaluronic Acid analog results in increased phosphorylation of MAP2K1 protein CTD PMID:12402308 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 increases phosphorylation EXP Hyaluronic Acid analog results in increased phosphorylation of MAP2K2 protein CTD PMID:12402308 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 multiple interactions ISO Hyaluronic Acid analog affects the localization of [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog promotes the reaction [MAP3K1 protein binds to CD44 protein]; Hyaluronic Acid analog results in increased phosphorylation of and results in increased activity of MAP3K1 protein CTD PMID:20159036 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152
JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 multiple interactions ISO MAP3K3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr17:63,622,417...63,696,305
Ensembl chr17:63,622,415...63,696,305
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
EXP
ISO
Hyaluronic Acid analog results in increased phosphorylation of MAPK1 protein
MAPK1 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; U 0126 inhibits the reaction [Hyaluronic Acid analog results in increased phosphorylation of MAPK1 protein]
CTD PMID:12402308 PMID:20159036 PMID:20633555 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
EXP
ISO
Hyaluronic Acid analog results in increased phosphorylation of MAPK3 protein
MAPK3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; U 0126 inhibits the reaction [Hyaluronic Acid analog results in increased phosphorylation of MAPK3 protein]
CTD PMID:12402308 PMID:20159036 PMID:20633555 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 multiple interactions ISO MAPK7 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr17:19,377,750...19,383,544
Ensembl chr17:19,377,721...19,383,544
JBrowse link
G MFN1 mitofusin 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of MFN1 protein CTD PMID:23178681 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions ISO [Hyaluronic Acid co-treated with Resveratrol] results in decreased expression of MMP1 mRNA CTD PMID:23595953 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions
increases expression
ISO [Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP13 mRNA
Hyaluronic Acid metabolite results in increased expression of MMP13 mRNA; Hyaluronic Acid metabolite results in increased expression of MMP13 protein
CTD PMID:23595953 PMID:23692848 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP2 matrix metallopeptidase 2 affects activity ISO Hyaluronic Acid affects the activity of MMP2 protein CTD PMID:15597151 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions ISO [Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP3 mRNA CTD PMID:23595953 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP9 matrix metallopeptidase 9 affects activity ISO Hyaluronic Acid affects the activity of MMP9 protein CTD PMID:15597151 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase multiple interactions ISO [Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein] CTD PMID:14697411 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MRPS7 mitochondrial ribosomal protein S7 decreases expression ISO Hyaluronic Acid analog results in decreased expression of MRPS7 protein CTD PMID:23178681 NCBI chr17:75,261,879...75,266,376
Ensembl chr17:75,261,674...75,266,376
JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MUS81 protein]
Hyaluronic Acid analog results in decreased expression of MUS81 protein
CTD PMID:23178681 NCBI chr11:65,859,674...65,867,653
Ensembl chr11:65,857,126...65,867,653
JBrowse link
G MYL12A myosin light chain 12A multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MYL12A protein]
Hyaluronic Acid analog results in decreased expression of MYL12A protein
CTD PMID:23178681 NCBI chr18:3,247,482...3,256,237
Ensembl chr18:3,247,481...3,256,236
JBrowse link
G MYL12B myosin light chain 12B decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of MYL12B protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of MYL12B protein]
CTD PMID:23178681 NCBI chr18:3,262,133...3,278,461
Ensembl chr18:3,261,479...3,278,461
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP
Hyaluronic Acid metabolite results in increased activity of [NFKB1 protein binds to RELA protein]
[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein]
CTD PMID:17879260 PMID:23692848 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases phosphorylation
EXP
ISO
[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein]
Hyaluronic Acid results in decreased phosphorylation of NFKBIA protein
CTD PMID:17879260 PMID:33383130 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 increases expression ISO Hyaluronic Acid results in increased expression of NLRP3 mRNA; Hyaluronic Acid results in increased expression of NLRP3 protein CTD PMID:33383130 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression
multiple interactions
ISO Hyaluronic Acid analog results in decreased expression of NME1 protein
Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NME1 protein]
CTD PMID:23178681 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NME2 protein]
Hyaluronic Acid analog results in decreased expression of NME2 protein
CTD PMID:23178681 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
JBrowse link
G NOS2 nitric oxide synthase 2 affects expression
increases expression
ISO Hyaluronic Acid affects the expression of NOS2 mRNA
Hyaluronic Acid metabolite results in increased expression of NOS2 mRNA; Hyaluronic Acid metabolite results in increased expression of NOS2 protein
CTD PMID:15597151 PMID:23692848 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 decreases expression EXP Hyaluronic Acid results in decreased expression of NR1D1 mRNA CTD PMID:17075855 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
JBrowse link
G NRXN1 neurexin 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRXN1 protein] CTD PMID:23178681 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
JBrowse link
G OPTN optineurin multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of OPTN protein] CTD PMID:23178681 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308
JBrowse link
G PDE4D phosphodiesterase 4D decreases expression ISO Hyaluronic Acid analog results in decreased expression of PDE4D protein CTD PMID:23178681 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PDIA3 protein CTD PMID:23178681 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PDIA6 protein] CTD PMID:23178681 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977
JBrowse link
G PGAM1 phosphoglycerate mutase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGAM1 protein] CTD PMID:23178681 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444
JBrowse link
G PGK1 phosphoglycerate kinase 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PGK1 protein CTD PMID:23178681 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295
JBrowse link
G PGLS 6-phosphogluconolactonase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGLS protein] CTD PMID:23178681 NCBI chr19:17,511,649...17,521,288
Ensembl chr19:17,511,636...17,521,288
JBrowse link
G PHB1 prohibitin 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHB1 protein] CTD PMID:23178681 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
JBrowse link
G PHGDH phosphoglycerate dehydrogenase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHGDH protein] CTD PMID:23178681 NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha increases phosphorylation EXP Hyaluronic Acid results in increased phosphorylation of PIK3CA protein CTD PMID:16864594 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PITPNA phosphatidylinositol transfer protein alpha multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PITPNA protein] CTD PMID:23178681 NCBI chr17:1,517,718...1,562,792
Ensembl chr17:1,517,718...1,562,792
JBrowse link
G PLAU plasminogen activator, urokinase multiple interactions EXP [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU protein CTD PMID:12402308 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLAUR plasminogen activator, urokinase receptor multiple interactions EXP [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR mRNA; [Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR protein CTD PMID:12402308 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547
JBrowse link
G PLS3 plastin 3 multiple interactions
increases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of PLS3 protein
Hyaluronic Acid analog results in increased expression of PLS3 protein
CTD PMID:23178681 NCBI chr  X:115,561,174...115,650,861
Ensembl chr  X:115,561,174...115,650,861
JBrowse link
G PPIA peptidylprolyl isomerase A multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of PPIA protein
Hyaluronic Acid analog results in decreased expression of PPIA protein
CTD PMID:23178681 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha multiple interactions ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in increased expression of PPP1CA protein CTD PMID:23178681 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
JBrowse link
G PRDX1 peroxiredoxin 1 affects expression ISO Hyaluronic Acid analog affects the expression of PRDX1 protein CTD PMID:23178681 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRDX2 peroxiredoxin 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PRDX2 protein CTD PMID:23178681 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G PRDX6 peroxiredoxin 6 multiple interactions
affects expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PRDX6 protein]
Hyaluronic Acid analog affects the expression of PRDX6 protein
CTD PMID:23178681 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G PRPH peripherin decreases expression ISO Hyaluronic Acid analog results in decreased expression of PRPH protein CTD PMID:23178681 NCBI chr12:49,295,147...49,298,686
Ensembl chr12:49,295,147...49,298,686
JBrowse link
G PSMB1 proteasome 20S subunit beta 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMB1 protein] CTD PMID:23178681 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307
JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PSMC2 protein] CTD PMID:23178681 NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMC4 protein]
Hyaluronic Acid analog results in decreased expression of PSMC4 protein
CTD PMID:23178681 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 decreases expression ISO Hyaluronic Acid analog results in decreased expression of PSMC5 protein CTD PMID:23178681 NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026
JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of PTK2 protein] CTD PMID:23178681 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G RACK1 receptor for activated C kinase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RACK1 protein] CTD PMID:23178681 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096
JBrowse link
G RAN RAN, member RAS oncogene family multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RAN protein]
Hyaluronic Acid analog results in decreased expression of RAN protein
CTD PMID:23178681 NCBI chr12:130,872,066...130,877,678
Ensembl chr12:130,872,037...130,877,678
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
EXP
ISO
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein; [[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]
Hyaluronic Acid results in increased phosphorylation of RELA protein
Hyaluronic Acid metabolite results in increased phosphorylation of RELA protein
Hyaluronic Acid metabolite results in increased activity of [NFKB1 protein binds to RELA protein]
CTD PMID:17879260 PMID:19047049 PMID:23692848 PMID:31226360 PMID:33383130 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RENBP renin binding protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RENBP protein] CTD PMID:23178681 NCBI chr  X:153,935,269...153,944,643
Ensembl chr  X:153,935,269...153,944,687
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 increases phosphorylation EXP Hyaluronic Acid results in increased phosphorylation of ROCK1 protein CTD PMID:16864594 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813
JBrowse link
G RPS12 ribosomal protein S12 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RPS12 protein]
Hyaluronic Acid analog results in decreased expression of RPS12 protein
CTD PMID:23178681 NCBI chr 6:132,814,569...132,817,564
Ensembl chr 6:132,814,569...132,817,564
JBrowse link
G SCRN1 secernin 1 multiple interactions
decreases expression
ISO [Hyaluronic Acid analog co-treated with Hydrogen Peroxide] results in decreased expression of SCRN1 protein
Hyaluronic Acid analog results in decreased expression of SCRN1 protein
CTD PMID:23178681 NCBI chr 7:29,920,103...29,990,289
Ensembl chr 7:29,920,104...29,990,289
JBrowse link
G SEPTIN11 septin 11 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SEPTIN11 protein]
Hyaluronic Acid analog results in decreased expression of SEPTIN11 protein
CTD PMID:23178681 NCBI chr 4:76,949,752...77,040,154
Ensembl chr 4:76,949,751...77,040,384
JBrowse link
G SEPTIN2 septin 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of SEPTIN2 protein CTD PMID:23178681 NCBI chr 2:241,315,355...241,354,027
Ensembl chr 2:241,315,100...241,354,027
JBrowse link
G SERPINH1 serpin family H member 1 multiple interactions
affects expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SERPINH1 protein]
Hyaluronic Acid analog affects the expression of SERPINH1 protein
CTD PMID:23178681 NCBI chr11:75,562,253...75,572,783
Ensembl chr11:75,562,056...75,572,783
JBrowse link
G SLC25A11 solute carrier family 25 member 11 decreases expression ISO Hyaluronic Acid analog results in decreased expression of SLC25A11 protein CTD PMID:23178681 NCBI chr17:4,937,130...4,940,046
Ensembl chr17:4,937,130...4,940,053
JBrowse link
G SLMAP sarcolemma associated protein decreases expression ISO Hyaluronic Acid analog results in decreased expression of SLMAP protein CTD PMID:23178681 NCBI chr 3:57,756,309...57,930,013
Ensembl chr 3:57,755,450...57,930,003
JBrowse link
G SMAD2 SMAD family member 2 multiple interactions EXP [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]; [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SNAI2 snail family transcriptional repressor 2 increases expression ISO Hyaluronic Acid analog results in increased expression of SNAI2 mRNA; Hyaluronic Acid analog results in increased expression of SNAI2 protein CTD PMID:20159036 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SNCB synuclein beta decreases expression ISO Hyaluronic Acid analog results in decreased expression of SNCB protein CTD PMID:23178681 NCBI chr 5:176,620,082...176,630,534
Ensembl chr 5:176,620,082...176,630,556
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of SOD1 protein CTD PMID:23178681 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD3 superoxide dismutase 3 affects binding
multiple interactions
ISO SOD3 protein binds to Hyaluronic Acid
SOD3 protein inhibits the reaction [[Copper co-treated with Hydrogen Peroxide] results in increased degradation of Hyaluronic Acid]
CTD PMID:18165226 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SORD sorbitol dehydrogenase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of SORD protein] CTD PMID:23178681 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185
JBrowse link
G SOX9 SRY-box transcription factor 9 multiple interactions ISO [Hyaluronic Acid co-treated with resveratrol] results in increased expression of SOX9 mRNA CTD PMID:23595953 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of SRC protein] CTD PMID:23178681 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STAM2 signal transducing adaptor molecule 2 decreases expression ISO Hyaluronic Acid analog results in decreased expression of STAM2 protein CTD PMID:23178681 NCBI chr 2:152,116,801...152,175,763
Ensembl chr 2:152,116,801...152,175,763
JBrowse link
G STIP1 stress induced phosphoprotein 1 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of STIP1 protein]
Hyaluronic Acid analog results in decreased expression of STIP1 protein
CTD PMID:23178681 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543
JBrowse link
G TCP1 t-complex 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TCP1 protein] CTD PMID:23178681 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP [CD44 protein affects the abundance of Hyaluronic Acid] affects the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:31285260 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 multiple interactions
increases abundance
ISO MAP3K3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK1 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK3 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid]; MAPK7 protein promotes the reaction [TGFB2 protein results in increased abundance of Hyaluronic Acid] CTD PMID:20633555 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TLR2 toll like receptor 2 increases expression
multiple interactions
ISO Hyaluronic Acid metabolite results in increased expression of TLR2 mRNA; Hyaluronic Acid metabolite results in increased expression of TLR2 protein
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR2 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR2 protein]
CTD PMID:23692848 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260
JBrowse link
G TLR4 toll like receptor 4 multiple interactions
increases expression
increases abundance
ISO
EXP
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 protein]
Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA; Hyaluronic Acid metabolite results in increased expression of TLR4 protein
TLR4 protein results in increased abundance of Hyaluronic Acid
[Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]
CTD PMID:23692848 PMID:25053413 PMID:31226360 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases abundance
increases expression
ISO
EXP
[Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of TNF protein; [Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of TNF protein]; [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of TNF protein
TNF mRNA results in increased abundance of Hyaluronic Acid
Hyaluronic Acid metabolite results in increased expression of TNF mRNA; Hyaluronic Acid metabolite results in increased expression of TNF protein
CTD PMID:14697411 PMID:23692848 PMID:25053413 PMID:25106431 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 affects binding
multiple interactions
EXP TNFAIP6 protein modified form binds to Hyaluronic Acid
TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Hyaluronic Acid]
CTD PMID:12401803 PMID:25561734 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TPM2 tropomyosin 2 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TPM2 protein] CTD PMID:23178681 NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056
JBrowse link
G TPM3 tropomyosin 3 multiple interactions
decreases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TPM3 protein]
Hyaluronic Acid analog results in decreased expression of TPM3 protein
CTD PMID:23178681 NCBI chr 1:154,155,308...154,192,100
Ensembl chr 1:154,155,308...154,194,648
JBrowse link
G TPT1 tumor protein, translationally-controlled 1 decreases expression ISO Hyaluronic Acid analog results in decreased expression of TPT1 protein CTD PMID:23178681 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284
JBrowse link
G TUBB tubulin beta class I multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of TUBB5 protein] CTD PMID:23178681 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538
JBrowse link
G VCP valosin containing protein multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of VCP protein] CTD PMID:23178681 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions EXP Hyaluronic Acid promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein] CTD PMID:20067761 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIM vimentin increases expression
multiple interactions
affects expression
ISO Hyaluronic Acid analog results in increased expression of VIM protein
Hyaluronic Acid analog affects the reaction [Hydrogen Peroxide affects the expression of VIM protein]
Hyaluronic Acid analog affects the expression of VIM protein
CTD PMID:20159036 PMID:23178681 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes multiple interactions
increases expression
ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of VPS33A protein]
Hyaluronic Acid analog results in increased expression of VPS33A protein
CTD PMID:23178681 NCBI chr12:122,229,564...122,266,494
Ensembl chr12:122,229,564...122,266,502
JBrowse link
G WDR1 WD repeat domain 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of WDR1 protein] CTD PMID:23178681 NCBI chr 4:10,074,339...10,116,799
Ensembl chr 4:10,068,089...10,116,972
JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 multiple interactions ISO Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of YARS1 protein] CTD PMID:23178681 NCBI chr 1:32,775,239...32,817,358
Ensembl chr 1:32,775,237...32,818,031
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26489
    chemical entity 26469
      molecular entity 26451
        polyatomic entity 26276
          macromolecule 9606
            biomacromolecule 9130
              exopolysaccharide 263
                (1->3)-beta-D-glucan + 1
                alginic acid 24
                amorphous cellulose 0
                chitosan 63
                crystalline cellulose 0
                dextran 5
                galactosaminogalactan 0
                galactoxylomannan 0
                hyaluronic acid 204
                indican 0
                mucilage 0
                pullulan 0
                schizophyllan 0
                succinoglucan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26489
    subatomic particle 26465
      composite particle 26457
        hadron 26457
          baryon 26465
            nucleon 26457
              atomic nucleus 26465
                atom 26457
                  main group element atom 26200
                    p-block element atom 26192
                      carbon group element atom 25635
                        carbon atom 25598
                          organic molecular entity 25598
                            biomacromolecule 9130
                              exopolysaccharide 263
                                (1->3)-beta-D-glucan + 1
                                alginic acid 24
                                amorphous cellulose 0
                                chitosan 63
                                crystalline cellulose 0
                                dextran 5
                                galactosaminogalactan 0
                                galactoxylomannan 0
                                hyaluronic acid 204
                                indican 0
                                mucilage 0
                                pullulan 0
                                schizophyllan 0
                                succinoglucan 0
paths to the root