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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:asperentin
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Accession:CHEBI:68792 term browser browse the term
Definition:A member of the class of isocoumarins that is 6,8-dihydroxy-3,4-dihydro-1H-isochromen-1-one substituted by a [6-methyltetrahydro-2H-pyran-2-yl]methyl group at position 3. It has been isolated from the fungus Chaetomium globosum and Aspergillus flavus.
Synonyms:exact_synonym: 6,8-dihydroxy-3-{[(2R,6S)-6-methyltetrahydro-2H-pyran-2-yl]methyl}-3,4-dihydro-1H-isochromen-1-one
 related_synonym: 3,4-dihydro-6,8-dihydroxy-3-(tetrahydro-6-methyl-H-pyran-2-yl)methylisocoumarin;   Formula=C16H20O5;   InChI=1S/C16H20O5/c1-9-3-2-4-12(20-9)8-13-6-10-5-11(17)7-14(18)15(10)16(19)21-13/h5,7,9,12-13,17-18H,2-4,6,8H2,1H3/t9-,12+,13?/m0/s1;   InChIKey=WOMKDMUZNBFXKG-XAWKZAOJSA-N;   SMILES=[H][C@@]1(CCC[C@H](C)O1)CC1Cc2cc(O)cc(O)c2C(=O)O1;   cladosporin
 xref: CAS:35818-31-6;   Chemspider:34206
 xref_mesh: MESH:C000488
 xref: PMID:17125234;   PMID:22663064;   PMID:22704625;   PMID:23413753;   PMID:4629903;   PMID:5169000;   Reaxys:5086911


show annotations for term's descendants           Sort by:
asperentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO cladosporin results in increased expression of ABCF1 mRNA CTD PMID:19818335 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433 		JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO cladosporin results in increased expression of AIMP1 mRNA CTD PMID:19818335 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728 		JBrowse link
G Blvrb biliverdin reductase B increases expression ISO cladosporin results in increased expression of BLVRB mRNA CTD PMID:21356202 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression ISO cladosporin results in increased expression of CCL12 mRNA CTD PMID:21356202 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO cladosporin results in increased expression of CCL19 mRNA CTD PMID:19818335 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
decreases expression		 ISO cladosporin results in increased expression of CCL20 mRNA
cladosporin results in decreased expression of CCL20 mRNA		 CTD PMID:19818335 PMID:21356202 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 increases expression ISO cladosporin results in increased expression of CCL25 mRNA CTD PMID:19818335 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO cladosporin results in decreased expression of CCL3 mRNA CTD PMID:19818335 PMID:21356202 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO cladosporin results in decreased expression of CCL4 mRNA CTD PMID:19818335 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO cladosporin results in decreased expression of CCL7 mRNA CTD PMID:19818335 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO cladosporin results in increased expression of CCR1 mRNA CTD PMID:19818335 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO cladosporin results in increased expression of CCR10 mRNA CTD PMID:19818335 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO cladosporin results in increased expression of CCR2 mRNA CTD PMID:19818335 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO cladosporin results in increased expression of CCR3 mRNA CTD PMID:19818335 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO cladosporin results in increased expression of CCR4 mRNA CTD PMID:19818335 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 increases expression ISO cladosporin results in increased expression of CCR6 mRNA CTD PMID:19818335 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO cladosporin results in increased expression of CCR7 mRNA CTD PMID:19818335 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO cladosporin results in increased expression of CCR9 mRNA CTD PMID:19818335 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969 		JBrowse link
G Cd40lg CD40 ligand increases expression ISO cladosporin results in increased expression of CD40LG mRNA CTD PMID:19818335 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO cladosporin results in increased expression of CX3CL1 mRNA CTD PMID:19818335 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression		 ISO cladosporin results in decreased expression of CXCL10 mRNA
cladosporin results in increased expression of CXCL10 protein		 CTD PMID:19818335 PMID:21356202 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression ISO cladosporin results in decreased expression of CXCL11 mRNA CTD PMID:19818335 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO cladosporin results in increased expression of CXCL12 mRNA CTD PMID:19818335 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO cladosporin results in increased expression of CXCL13 mRNA CTD PMID:19818335 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO cladosporin results in increased expression of CXCL2 mRNA; cladosporin results in increased expression of CXCL2 protein CTD PMID:19818335 PMID:21356202 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases expression		 ISO cladosporin results in decreased expression of CXCL1 mRNA
cladosporin results in increased expression of CXCL1 mRNA		 CTD PMID:19818335 PMID:21356202 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression ISO cladosporin results in decreased expression of CXCL5 mRNA CTD PMID:19818335 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression
increases expression		 ISO cladosporin results in decreased expression of CXCR2 mRNA
cladosporin results in increased expression of CXCR2 mRNA		 CTD PMID:19818335 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO cladosporin results in increased expression of CXCR3 mRNA CTD PMID:19818335 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO cladosporin results in increased expression of CXCR5 mRNA CTD PMID:19818335 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO cladosporin results in decreased expression of IFI27L1 mRNA CTD PMID:21356202 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifng interferon gamma increases expression ISO cladosporin results in increased expression of IFNG mRNA CTD PMID:19818335 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 increases expression ISO cladosporin results in increased expression of IL10 mRNA CTD PMID:19818335 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO cladosporin results in increased expression of IL10RA mRNA CTD PMID:19818335 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO cladosporin results in increased expression of IL10RB mRNA CTD PMID:19818335 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074 		JBrowse link
G Il15 interleukin 15 increases expression ISO cladosporin results in increased expression of IL15 mRNA CTD PMID:19818335 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il16 interleukin 16 increases expression ISO cladosporin results in increased expression of IL16 mRNA CTD PMID:19818335 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il18 interleukin 18 increases expression ISO cladosporin results in increased expression of IL18 mRNA CTD PMID:19818335 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression		 ISO cladosporin results in increased expression of IL1B mRNA
cladosporin results in decreased expression of IL1B mRNA		 CTD PMID:19818335 PMID:21356202 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO cladosporin results in increased expression of IL1R1 mRNA CTD PMID:19818335 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta increases expression ISO cladosporin results in increased expression of IL2RB mRNA CTD PMID:19818335 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il4 interleukin 4 increases expression ISO cladosporin results in increased expression of IL4 mRNA CTD PMID:19818335 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha increases expression ISO cladosporin results in increased expression of IL5RA mRNA CTD PMID:19818335 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 increases expression ISO cladosporin results in increased expression of IL6 mRNA CTD PMID:21356202 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor increases expression ISO cladosporin results in increased expression of IL6RA mRNA CTD PMID:19818335 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO cladosporin results in decreased expression of IL6ST mRNA CTD PMID:19818335 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO cladosporin results in increased expression of ITGAM mRNA CTD PMID:19818335 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Lta lymphotoxin alpha increases expression ISO cladosporin results in increased expression of LTA mRNA CTD PMID:19818335 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltb lymphotoxin beta increases expression ISO cladosporin results in increased expression of LTB mRNA CTD PMID:19818335 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO cladosporin results in increased expression of MIF mRNA CTD PMID:19818335 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO cladosporin results in increased expression of SPP1 mRNA CTD PMID:19818335 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression		 ISO cladosporin results in decreased expression of TNF mRNA
cladosporin results in increased expression of TNF mRNA		 CTD PMID:19818335 PMID:21356202 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO cladosporin results in increased expression of TNFRSF1A mRNA CTD PMID:19818335 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        antimicrobial agent 18269
          antifungal agent 17182
            asperentin 53
              5'-hydroxy-asperentin-8-O-methylether 0
              5'-hydroxyasperentin 0
              asperentin-8-methyl ether 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            heteroorganic entity 19532
                              organochalcogen compound 19293
                                organooxygen compound 19209
                                  ester 17488
                                    carboxylic ester 16778
                                      lactone 13319
                                        delta-lactone 4214
                                          isocoumarins 1446
                                            asperentin 53
                                              5'-hydroxy-asperentin-8-O-methylether 0
                                              5'-hydroxyasperentin 0
                                              asperentin-8-methyl ether 0
paths to the root