CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: methomyl
Accession: CHEBI:6835
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Definition: A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.
Synonyms: exact_synonym: methyl N-(methylcarbamoyloxy)ethanimidothioate
related_synonym: 1-(Methylthio)acetaldehyde O-methylcarbamoyloxime; 1-(Methylthio)ethylideneamino methylcarbamate; Formula=C5H10N2O2S; InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8); InChIKey=UHXUZOCRWCRNSJ-UHFFFAOYSA-N; Lannate; Methomyl lannate; N-(((methylamino)carbonyl)oxy)ethanimidothioic acid methyl ester; S-Methyl N-(methylcarbamoyloxy)thioacetimidate; SMILES=CNC(=O)ON=C(C)SC
xref: Beilstein:2042050; CAS:16752-77-5; HMDB:HMDB0031804; KEGG:C11196; LINCS:LSM-24991
xref_mesh: MESH:D008724
xref: PMID:11327381; PMID:11758270; PPDB:458; Pesticides:methomyl; Reaxys:2042050; Wikipedia:Methomyl
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Ache
acetylcholinesterase
multiple interactions decreases activity
ISO EXP
methamidophos promotes the reaction [Methomyl results in decreased activity of ACHE protein]; Methomyl promotes the reaction [methamidophos results in decreased activity of ACHE protein]
CTD
PMID:8134223 PMID:19371631 PMID:19934164 PMID:21251949 PMID:23962483 PMID:25707986 PMID:33844597 More...
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
Methomyl results in increased expression of BAX mRNA
CTD
PMID:34676817
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bche
butyrylcholinesterase
multiple interactions
EXP
[Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein
CTD
PMID:22649187
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
Methomyl results in decreased expression of BCL2 mRNA
CTD
PMID:34676817
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3
caspase 3
increases expression
ISO
Methomyl results in increased expression of CASP3 mRNA
CTD
PMID:34676817
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases activity
ISO
Methomyl results in increased activity of CYP19A1 protein
CTD
PMID:11884232
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Esr1
estrogen receptor 1
multiple interactions
ISO
Methomyl inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
CTD
PMID:9126867
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fshb
follicle stimulating hormone subunit beta
increases expression
EXP
Methomyl results in increased expression of FSHB protein
CTD
PMID:11516254
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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Hsp90b1
heat shock protein 90 beta family member 1
decreases expression
ISO
Methomyl results in decreased expression of HSP90B1 protein
CTD
PMID:16271832
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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Hspa1a
heat shock protein family A (Hsp70) member 1A
decreases expression
ISO
Methomyl results in decreased expression of HSPA1A protein
CTD
PMID:16271832
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa5
heat shock protein family A (Hsp70) member 5
increases expression
ISO
Methomyl results in increased expression of HSPA5 protein
CTD
PMID:16271832
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspa8
heat shock protein family A (Hsp70) member 8
decreases expression
ISO
Methomyl results in decreased expression of HSPA8 protein
CTD
PMID:16271832
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Kyat1
kynurenine aminotransferase 1
decreases activity
ISO
Methomyl results in decreased activity of KYAT1 protein
CTD
PMID:7175100
NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
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Kynu
kynureninase
decreases activity
ISO
Methomyl results in decreased activity of KYNU protein
CTD
PMID:7175100
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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Lhb
luteinizing hormone subunit beta
increases expression
EXP
Methomyl results in increased expression of LHB protein
CTD
PMID:11516254
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Pgr
progesterone receptor
multiple interactions
ISO
Methomyl inhibits the reaction [Progesterone results in increased activity of PGR protein]
CTD
PMID:9126867
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Prl
prolactin
increases expression
EXP
Methomyl results in increased expression of PRL protein
CTD
PMID:11516254
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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S100a1
S100 calcium binding protein A1
multiple interactions
EXP
Methomyl results in increased expression of and affects the localization of S100A1 protein
CTD
PMID:30472887
NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
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Tpt1
tumor protein, translationally-controlled 1
increases expression
EXP
Methomyl results in increased expression of TPT1 protein
CTD
PMID:30472887
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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Ache
acetylcholinesterase
decreases activity
ISO EXP
thiodicarb results in decreased activity of ACHE protein
CTD
PMID:21251949
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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