CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: myristicin
Accession: CHEBI:68234
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Definition: An organic molecular entity that has formula C11H12O3.
Synonyms: related_synonym: 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-; 6-Allyl-4-methoxy-1,3-benzodioxole; Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-; Formula=C11H12O3; InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3; InChIKey=BNWJOHGLIBDBOB-UHFFFAOYSA-N; SMILES=C12=C(OCO1)C=C(C=C2OC)CC=C
alt_id: CHEBI:7057
xref: CAS:607-91-0; HMDB:HMDB0035873; KEGG:C10480; KNApSAcK:C00002762
xref_mesh: MESH:C005246
xref: PMID:20879744; PMID:21049975
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Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
decreases expression
ISO
myristicin results in decreased expression of ABL1 mRNA
CTD
PMID:24792648
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
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Ankrd17
ankyrin repeat domain 17
decreases expression
ISO
myristicin results in decreased expression of ANKRD17 mRNA
CTD
PMID:24792648
NCBI chr14:17,723,239...17,861,841
Ensembl chr14:18,008,859...18,145,980
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Atm
ATM serine/threonine kinase
decreases expression
ISO
myristicin results in decreased expression of ATM mRNA
CTD
PMID:24792648
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
myristicin results in increased expression of BAX mRNA
CTD
PMID:29174417 PMID:38779996
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
myristicin results in decreased expression of BCL2 mRNA
CTD
PMID:29174417 PMID:38779996
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bid
BH3 interacting domain death agonist
increases expression
ISO
myristicin results in increased expression of BID mRNA
CTD
PMID:38779996
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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Brca1
BRCA1, DNA repair associated
decreases expression
ISO
myristicin results in decreased expression of BRCA1 mRNA
CTD
PMID:24792648
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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Btg2
BTG anti-proliferation factor 2
decreases expression
ISO
myristicin results in decreased expression of BTG2 mRNA
CTD
PMID:24792648
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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Casp3
caspase 3
increases activity
ISO
myristicin results in increased activity of CASP3 protein
CTD
PMID:24792648
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp8
caspase 8
increases expression
ISO
myristicin results in increased expression of CASP8 mRNA
CTD
PMID:38779996
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
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Casp9
caspase 9
increases activity increases cleavage
ISO
myristicin results in increased activity of CASP9 protein myristicin results in increased cleavage of CASP9 protein
CTD
PMID:29174417 PMID:38779996
Ensembl chr 5:159,391,188...159,409,648
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Cat
catalase
decreases activity
ISO
myristicin results in decreased activity of CAT protein
CTD
PMID:38779996
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
myristicin results in decreased expression of CDK1 mRNA
CTD
PMID:38779996
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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Cdk7
cyclin-dependent kinase 7
increases expression
ISO
myristicin results in increased expression of CDK7 mRNA
CTD
PMID:24792648
NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485
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Chek2
checkpoint kinase 2
decreases expression
ISO
myristicin results in decreased expression of CHEK2 mRNA
CTD
PMID:24792648
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
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Cycs
cytochrome c, somatic
increases expression
ISO
myristicin results in increased expression of CYCS protein
CTD
PMID:38779996
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression multiple interactions
ISO
myristicin results in increased expression of CYP1A1 mRNA myristicin results in increased expression of and results in increased activity of CYP1A1 protein
CTD
PMID:9168900
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
affects oxidation multiple interactions decreases activity
ISO
CYP1A2 protein affects the oxidation of myristicin Glutathione inhibits the reaction [myristicin results in decreased activity of CYP1A2 protein]
CTD
PMID:12523956 PMID:26091900
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
affects oxidation
ISO
CYP3A4 protein affects the oxidation of myristicin
CTD
PMID:12523956
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Dmc1
DNA meiotic recombinase 1
decreases expression
ISO
myristicin results in decreased expression of DMC1 mRNA
CTD
PMID:24792648
NCBI chr 7:113,005,278...113,047,854
Ensembl chr 7:113,005,281...113,047,854
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Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
decreases expression
ISO
myristicin results in decreased expression of ERCC1 mRNA
CTD
PMID:24792648
NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120
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Ercc2
ERCC excision repair 2, TFIIH core complex helicase subunit
decreases expression
ISO
myristicin results in decreased expression of ERCC2 mRNA
CTD
PMID:24792648
NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
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Fen1
flap structure-specific endonuclease 1
decreases expression
ISO
myristicin results in decreased expression of FEN1 mRNA
CTD
PMID:24792648
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
decreases expression
ISO
myristicin results in decreased expression of GADD45A mRNA
CTD
PMID:24792648
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
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Gadd45g
growth arrest and DNA-damage-inducible, gamma
decreases expression
ISO
myristicin results in decreased expression of GADD45G mRNA
CTD
PMID:24792648
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,528,610...13,530,369
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Hus1
HUS1 checkpoint clamp component
decreases expression
ISO
myristicin results in decreased expression of HUS1 mRNA
CTD
PMID:24792648
NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134
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Ighmbp2
immunoglobulin mu DNA binding protein 2
decreases expression
ISO
myristicin results in decreased expression of IGHMBP2 mRNA
CTD
PMID:24792648
NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:209,934,969...209,958,766
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Map3k20
mitogen-activated protein kinase kinase kinase 20
decreases expression
ISO
myristicin results in decreased expression of MAP3K20 mRNA
CTD
PMID:24792648
NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538
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Mapk12
mitogen-activated protein kinase 12
decreases expression
ISO
myristicin results in decreased expression of MAPK12 mRNA
CTD
PMID:24792648
NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:122,085,913...122,096,307
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Mlh3
mutL homolog 3
decreases expression
ISO
myristicin results in decreased expression of MLH3 mRNA
CTD
PMID:24792648
NCBI chr 6:104,881,483...104,917,686
Ensembl chr 6:110,612,535...110,648,999
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Mre11
MRE11 homolog, double strand break repair nuclease
decreases expression
ISO
myristicin results in decreased expression of MRE11 mRNA
CTD
PMID:24792648
NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904
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Msh3
mutS homolog 3
decreases expression
ISO
myristicin results in decreased expression of MSH3 mRNA
CTD
PMID:24792648
NCBI chr 2:25,179,400...25,320,857
Ensembl chr 2:25,179,400...25,321,102
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Mutyh
mutY DNA glycosylase
decreases expression
ISO
myristicin results in decreased expression of MUTYH mRNA
CTD
PMID:24792648
NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:135,517,695...135,522,776
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N4bp2
NEDD4 binding protein 2
decreases expression
ISO
myristicin results in decreased expression of N4BP2 mRNA
CTD
PMID:24792648
NCBI chr14:42,342,690...42,479,861
Ensembl chr14:42,763,601...42,825,039
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Nbn
nibrin
decreases expression
ISO
myristicin results in decreased expression of NBN mRNA
CTD
PMID:24792648
NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162
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Ogg1
8-oxoguanine DNA glycosylase
decreases expression
ISO
myristicin results in decreased expression of OGG1 mRNA
CTD
PMID:24792648
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:148,030,349...148,037,604
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P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
myristicin results in decreased expression of P4HB protein
CTD
PMID:38779996
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:106,335,300...106,346,911
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage decreases expression
ISO
myristicin results in increased cleavage of PARP1 protein myristicin results in decreased expression of PARP1 mRNA
CTD
PMID:24792648 PMID:38779996
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pms2
PMS1 homolog 2, mismatch repair system component
decreases expression
ISO
myristicin results in decreased expression of PMS2 mRNA
CTD
PMID:24792648
NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248
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Pnkp
polynucleotide kinase 3'-phosphatase
decreases expression
ISO
myristicin results in decreased expression of PNKP mRNA
CTD
PMID:24792648
NCBI chr 1:104,476,801...104,483,409
Ensembl chr 1:104,478,088...104,483,408
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
decreases expression
ISO
myristicin results in decreased expression of PPP1R15A mRNA
CTD
PMID:24792648
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:105,136,525...105,139,774
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Prkdc
protein kinase, DNA-activated, catalytic subunit
decreases expression
ISO
myristicin results in decreased expression of PRKDC mRNA
CTD
PMID:24792648
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:98,544,954...98,762,108
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Rad50
RAD50 double strand break repair protein
decreases expression
ISO
myristicin results in decreased expression of RAD50 mRNA
CTD
PMID:24792648
NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100
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Rad51
RAD51 recombinase
decreases expression
ISO
myristicin results in decreased expression of RAD51 mRNA
CTD
PMID:24792648
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
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Rad51b
RAD51 paralog B
decreases expression
ISO
myristicin results in decreased expression of RAD51B mRNA
CTD
PMID:24792648
NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:103,829,554...104,374,509
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Rad9a
RAD9 checkpoint clamp component A
decreases expression
ISO
myristicin results in decreased expression of RAD9A mRNA
CTD
PMID:24792648
NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161
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Rev1
REV1, DNA directed polymerase
decreases expression
ISO
myristicin results in decreased expression of REV1 mRNA
CTD
PMID:24792648
NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:47,773,907...47,847,332
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Sesn1
sestrin 1
decreases expression
ISO
myristicin results in decreased expression of SESN1 mRNA
CTD
PMID:24792648
NCBI chr20:45,294,876...45,387,698
Ensembl chr20:46,876,895...46,970,010
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Smc1a
structural maintenance of chromosomes 1A
decreases expression
ISO
myristicin results in decreased expression of SMC1A mRNA
CTD
PMID:24792648
NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462
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Tp53
tumor protein p53
increases expression
ISO
myristicin results in increased expression of TP53 mRNA
CTD
PMID:38779996
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tp73
tumor protein p73
decreases expression
ISO
myristicin results in decreased expression of TP73 mRNA
CTD
PMID:24792648
NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552
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Trex1
three prime repair exonuclease 1
decreases expression
ISO
myristicin results in decreased expression of TREX1 mRNA
CTD
PMID:24792648
NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:118,585,081...118,586,083
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Xrcc2
X-ray repair cross complementing 2
decreases expression
ISO
myristicin results in decreased expression of XRCC2 mRNA
CTD
PMID:24792648
NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:10,157,800...10,176,407
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Xrcc3
X-ray repair cross complementing 3
decreases expression increases expression
ISO
myristicin results in decreased expression of XRCC3 mRNA myristicin results in increased expression of XRCC3 mRNA
CTD
PMID:24792648
NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822
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