CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Methazolamide
Accession: CHEBI:6822
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Definition: A thiadiazole that has formula C5H8N4O3S2.
Synonyms: related_synonym: Formula=C5H8N4O3S2; InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+; InChIKey=FLOSMHQXBMRNHR-QPJJXVBHSA-N; SMILES=CC(=O)\\N=c1\\sc(nn1C)S(N)(=O)=O
xref: CAS:554-57-4; KEGG:C07764; KEGG:D00655
xref_mesh: MESH:D008704
G
Car1
carbonic anhydrase 1
multiple interactions
ISO
Methazolamide binds to and results in decreased activity of CA1 protein
CTD
PMID:17826101
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
G
Car2
carbonic anhydrase 2
decreases activity multiple interactions
ISO
Methazolamide results in decreased activity of CA2 protein Methazolamide binds to and results in decreased activity of CA2 protein
CTD
PMID:16858005 PMID:17826101
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
G
Car3
carbonic anhydrase 3
multiple interactions
ISO
Methazolamide binds to and results in decreased activity of CA3 protein
CTD
PMID:17826101
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
G
Clu
clusterin
affects expression
ISO
Methazolamide affects the expression of CLU protein
CTD
PMID:12388792
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Gal
galanin and GMAP prepropeptide
affects expression
ISO
Methazolamide affects the expression of GAL protein
CTD
PMID:12388792
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gap43
growth associated protein 43
affects expression
ISO
Methazolamide affects the expression of GAP43 protein
CTD
PMID:12388792
NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
G
Ret
ret proto-oncogene
affects expression
ISO
Methazolamide affects the expression of RET protein
CTD
PMID:12388792
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
G
Timp1
TIMP metallopeptidase inhibitor 1
affects expression
ISO
Methazolamide affects the expression of TIMP1 protein
CTD
PMID:12388792
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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