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G |
Aanat |
aralkylamine N-acetyltransferase |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of AANAT mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA] |
CTD |
PMID:19149911 |
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NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ABCA1 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein] |
CTD |
PMID:28223141 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
decreases expression multiple interactions |
ISO EXP |
Methamphetamine results in decreased expression of ABCC6 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of ABCD3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcd4 |
ATP binding cassette subfamily D member 4 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of ABCD4 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ABCG1 mRNA |
CTD |
PMID:35863504 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA Methamphetamine results in decreased expression of ABCG2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of ABL1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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G |
Ablim1 |
actin-binding LIM protein 1 |
increases expression |
ISO EXP |
Methamphetamine results in increased expression of ABLIM1 mRNA |
CTD |
PMID:26307267 PMID:32035215 |
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NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969
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G |
Abo2 |
histo-blood group ABO system transferase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ABO2 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 3:10,011,475...10,028,397
Ensembl chr 3:10,002,834...10,028,396
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G |
Abra |
actin-binding Rho activating protein |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA Methamphetamine results in increased expression of ABRA mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
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G |
Acacb |
acetyl-CoA carboxylase beta |
increases expression |
ISO |
Methamphetamine results in increased expression of ACACB mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acin1 |
apoptotic chromatin condensation inducer 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ACIN1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
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G |
Aco1 |
aconitase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of ACO1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Aco2 |
aconitase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ACO2 protein |
CTD |
PMID:19826936 |
|
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA Methamphetamine results in decreased expression of ACOT1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox3 |
acyl-CoA oxidase 3, pristanoyl |
increases expression |
EXP |
Methamphetamine results in increased expression of ACOX3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
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G |
Acrbp |
acrosin binding protein |
increases expression |
ISO |
Methamphetamine results in increased expression of ACRBP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:157,851,149...157,864,211
Ensembl chr 4:157,841,841...157,864,213
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of ACSL5 mRNA Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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G |
Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
affects response to substance |
ISO |
ACSL6 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression |
EXP |
Methamphetamine results in increased expression of ACTA2 protein |
CTD |
PMID:35863504 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actb |
actin, beta |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ACTB protein |
CTD |
PMID:19826936 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Actc1 |
actin, alpha, cardiac muscle 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ACTC1 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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G |
Actg1 |
actin, gamma 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ACTG1 protein |
CTD |
PMID:19826936 |
|
NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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G |
Acvrl1 |
activin A receptor like type 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of ACVRL1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADAM15 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
multiple interactions increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA Methamphetamine results in increased expression of ADAMTS9 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adamtsl5 |
ADAMTS-like 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADAMTSL5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:9,362,623...9,371,248
Ensembl chr 7:9,363,237...9,370,285
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G |
Adck2 |
aarF domain containing kinase 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ADCK2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
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G |
Adck5 |
aarF domain containing kinase 5 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ADCK5 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436
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G |
Adcy3 |
adenylate cyclase 3 |
multiple interactions decreases expression |
ISO |
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA] |
CTD |
PMID:11756511 |
|
NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
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G |
Adcy4 |
adenylate cyclase 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADCY4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
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G |
Adcy6 |
adenylate cyclase 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADCY6 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
|
NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
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G |
Add2 |
adducin 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ADD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
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G |
Adgrf5 |
adhesion G protein-coupled receptor F5 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADGRF5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADH1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADIPOQ mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adora1 |
adenosine A1 receptor |
multiple interactions |
ISO EXP |
[8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine]; [Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] which results in increased susceptibility to Methamphetamine |
CTD |
PMID:7996441 PMID:11043458 |
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NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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G |
Adora2a |
adenosine A2a receptor |
increases response to substance |
ISO |
ADORA2A gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:20799992 |
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NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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G |
Adora3 |
adenosine A3 receptor |
decreases expression affects response to substance |
EXP ISO |
Methamphetamine results in decreased expression of ADORA3 mRNA ADORA3 affects the susceptibility to Methamphetamine |
CTD |
PMID:19564919 PMID:21867746 |
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NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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G |
Adpgk |
ADP-dependent glucokinase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ADPGK mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:59,699,400...59,727,352
Ensembl chr 8:59,699,388...59,727,351
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G |
Adra1b |
adrenoceptor alpha 1B |
affects response to substance |
ISO |
ADRA1B protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12871582 |
|
NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
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G |
Agbl5 |
AGBL carboxypeptidase 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of AGBL5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
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G |
Agmat |
agmatinase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of AGMAT mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
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G |
Agrn |
agrin |
increases expression |
ISO |
Methamphetamine results in increased expression of AGRN mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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G |
Agt |
angiotensinogen |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of AGT protein candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein] |
CTD |
PMID:33421459 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression |
EXP |
Methamphetamine results in increased expression of AGTR1A protein |
CTD |
PMID:33421459 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Ahnak |
AHNAK nucleoprotein |
increases expression |
ISO |
Methamphetamine results in increased expression of AHNAK mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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G |
Ahsa2 |
activator of HSP90 ATPase homolog 2 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] |
CTD |
PMID:19564919 |
|
NCBI chr14:97,476,304...97,485,725
Ensembl chr14:97,476,817...97,485,657
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G |
Aif1 |
allograft inflammatory factor 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of AIF1 protein 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein] |
CTD |
PMID:26283213 PMID:29467000 PMID:32278788 PMID:32916201 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Ajap1 |
adherens junctions associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of AJAP1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:163,907,847...164,020,317
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G |
Ak1 |
adenylate kinase 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of AK1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
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G |
Ak5 |
adenylate kinase 5 |
affects response to substance |
ISO |
AK5 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
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G |
Akap13 |
A-kinase anchoring protein 13 |
increases expression |
ISO |
Methamphetamine results in increased expression of AKAP13 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
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G |
Akap8l |
A-kinase anchoring protein 8 like |
increases expression |
ISO |
Methamphetamine results in increased expression of AKAP8L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
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G |
Akr7a2 |
aldo-keto reductase family 7, member A2 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of AKR7A5 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases response to substance decreases phosphorylation multiple interactions affects phosphorylation increases phosphorylation increases cleavage |
ISO EXP |
AKT1 gene SNP results in increased susceptibility to Methamphetamine Methamphetamine results in decreased phosphorylation of AKT1 protein rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein] Methamphetamine affects the phosphorylation of AKT1 protein [Rosiglitazone co-treated with Methamphetamine] results in increased phosphorylation of AKT1 protein; VEGFA protein affects the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein] DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein; VEGFA protein affects the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein] Methamphetamine results in increased cleavage of AKT1 protein |
CTD |
PMID:15982448 PMID:26887589 PMID:29981415 PMID:30742852 PMID:31270305 PMID:32035215 PMID:34214594 PMID:35863504 PMID:35975811 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ALDH2 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldoc |
aldolase, fructose-bisphosphate C |
multiple interactions affects localization increases expression |
EXP |
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of ALDOC mRNA] Methamphetamine results in increased expression of ALDOC protein |
CTD |
PMID:18299792 PMID:19826936 |
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NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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G |
Alg1 |
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA Methamphetamine results in decreased expression of ALG1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:10,346,538...10,356,768
Ensembl chr10:10,346,536...10,356,750
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G |
Als2cl |
ALS2 C-terminal like |
increases expression |
ISO |
Methamphetamine results in increased expression of ALS2CL mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
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G |
Amdhd2 |
amidohydrolase domain containing 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of AMDHD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
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G |
Ampd1 |
adenosine monophosphate deaminase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of AMPD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
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G |
Ampd3 |
adenosine monophosphate deaminase 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of AMPD3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
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G |
Angel1 |
angel homolog 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ANGEL1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:106,349,125...106,386,202
Ensembl chr 6:106,349,126...106,386,209
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G |
Angpt2 |
angiopoietin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANGPT2 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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G |
Angptl2 |
angiopoietin-like 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANGPTL2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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G |
Ankrd1 |
ankyrin repeat domain 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANKRD1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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|
G |
Ankrd11 |
ankyrin repeat domain containing 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANKRD11 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
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G |
Ankrd16 |
ankyrin repeat domain 16 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ANKRD16 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:66,735,325...66,748,533
Ensembl chr17:66,737,261...66,748,533
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G |
Ankrd44 |
ankyrin repeat domain 44 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of ANKRD44 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 9:56,126,746...56,427,661
Ensembl chr 9:56,126,747...56,427,508
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G |
Ankrd9 |
ankyrin repeat domain 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANKRD9 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923
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|
G |
Anks1b |
ankyrin repeat and sterile alpha motif domain containing 1B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANKS1B mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693
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|
G |
Ano3 |
anoctamin 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ANO3 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
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|
G |
Ano6 |
anoctamin 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANO6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
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|
G |
Anxa3 |
annexin A3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ANXA3 protein |
CTD |
PMID:19826936 |
|
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
|
|
G |
Aoah |
acyloxyacyl hydrolase |
affects response to substance |
ISO |
AOAH gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148
|
|
G |
Ap1b1 |
adaptor related protein complex 1 subunit beta 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of AP1B1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
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|
G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of APEX2 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
|
|
G |
Aplnr |
apelin receptor |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of APLNR mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
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|
G |
Apoa2 |
apolipoprotein A2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of APOA2 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
|
|
G |
Apod |
apolipoprotein D |
decreases expression |
EXP |
Methamphetamine results in decreased expression of APOD mRNA |
CTD |
PMID:28619521 |
|
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
|
|
G |
Apold1 |
apolipoprotein L domain containing 1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA Methamphetamine results in increased expression of APOLD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
|
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G |
App |
amyloid beta precursor protein |
multiple interactions increases secretion increases expression |
EXP ISO |
Methamphetamine results in increased expression of and results in increased cleavage of APP protein Methamphetamine results in increased secretion of APP protein Rosiglitazone inhibits the reaction [Methamphetamine results in increased expression of APP protein] |
CTD |
PMID:30367931 PMID:31270305 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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|
G |
Appl2 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of APPL2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
|
|
G |
Ar |
androgen receptor |
increases expression |
EXP |
Methamphetamine results in increased expression of AR mRNA |
CTD |
PMID:15644446 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
|
|
G |
Arap3 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARAP3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555
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|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
multiple interactions increases expression |
EXP |
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA] |
CTD |
PMID:11085305 PMID:19564919 PMID:20298714 |
|
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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|
G |
Areg |
amphiregulin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AREG mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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|
G |
Arg2 |
arginase 2 |
multiple interactions increases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
|
|
G |
Arhgap29 |
Rho GTPase activating protein 29 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGAP29 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
|
|
G |
Arhgap9 |
Rho GTPase activating protein 9 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of ARHGAP9 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
|
|
G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
increases expression |
EXP |
Methamphetamine results in increased expression of ARHGDIA protein |
CTD |
PMID:19826936 |
|
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
|
|
G |
Arhgef1 |
Rho guanine nucleotide exchange factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
|
|
G |
Arhgef10 |
Rho guanine nucleotide exchange factor 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF10 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
|
|
G |
Arhgef15 |
Rho guanine nucleotide exchange factor 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF15 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:53,650,521...53,663,269
Ensembl chr10:53,650,553...53,663,913
|
|
G |
Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
|
|
G |
Arhgef25 |
Rho guanine nucleotide exchange factor 25 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of ARHGEF25 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 7:63,005,938...63,013,325
Ensembl chr 7:63,005,940...63,013,719
|
|
G |
Arid1a |
AT-rich interaction domain 1A |
increases methylation increases expression |
ISO |
Methamphetamine results in increased methylation of ARID1A promoter Methamphetamine results in increased expression of ARID1A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
|
|
G |
Arih1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of ARIH1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
|
|
G |
Arl14ep |
ADP-ribosylation factor like GTPase 14 effector protein |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ARL14EP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:93,441,952...93,454,282
Ensembl chr 3:93,443,183...93,454,155
|
|
G |
Arl5b |
ADP-ribosylation factor like GTPase 5B |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA Methamphetamine results in increased expression of ARL5B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ARNT2 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
|
|
G |
Arrb2 |
arrestin, beta 2 |
increases response to substance |
ISO |
ARRB2 gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:17233643 |
|
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
|
|
G |
Arrdc2 |
arrestin domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARRDC2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
|
|
G |
Asb14 |
ankyrin repeat and SOCS box-containing 14 |
increases expression |
ISO |
Methamphetamine results in increased expression of ASB14 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135
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|
G |
Asic3 |
acid sensing ion channel subunit 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of ASIC3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643
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G |
Asl |
argininosuccinate lyase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ASL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
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G |
Aspm |
assembly factor for spindle microtubules |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ASPM mRNA |
CTD |
PMID:25290377 |
|
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
|
|
G |
Astn2 |
astrotactin 2 |
affects response to substance |
ISO |
ASTN2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273
|
|
G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA] Methamphetamine results in increased expression of ATF3 mRNA; Methamphetamine results in increased expression of ATF3 protein |
CTD |
PMID:19564919 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
EXP ISO |
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] Methamphetamine results in increased expression of ATF4 mRNA; Methamphetamine results in increased expression of ATF4 protein ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein] |
CTD |
PMID:19564919 PMID:27323860 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
increases expression multiple interactions increases cleavage affects localization |
EXP ISO |
Methamphetamine results in increased expression of ATF6 mRNA; Methamphetamine results in increased expression of ATF6 protein Melatonin inhibits the reaction [Methamphetamine results in increased expression of ATF6 protein] ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]; Methamphetamine results in decreased expression of and results in increased cleavage of ATF6 protein; Naltrexone inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein] Methamphetamine affects the localization of ATF6 protein |
CTD |
PMID:19564919 PMID:27323860 PMID:28070110 PMID:34214594 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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|
G |
Atf6b |
activating transcription factor 6 beta |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of ATF6B protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein] |
CTD |
PMID:34214594 |
|
NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
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|
G |
Atg14 |
autophagy related 14 |
increases expression |
EXP |
Methamphetamine results in increased expression of ATG14 mRNA |
CTD |
PMID:32676729 |
|
NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
|
|
G |
Atg16l1 |
autophagy related 16-like 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of ATG16L1 mRNA |
CTD |
PMID:32676729 |
|
NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
|
|
G |
Atg2a |
autophagy related 2A |
increases expression |
EXP |
Methamphetamine results in increased expression of ATG2A mRNA |
CTD |
PMID:32676729 |
|
NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
|
|
G |
Atg5 |
autophagy related 5 |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of ATG5 mRNA; Methamphetamine results in increased expression of ATG5 protein Luteolin inhibits the reaction [Methamphetamine results in increased expression of ATG5 protein] |
CTD |
PMID:32035215 PMID:32676729 PMID:33359793 PMID:34374793 |
|
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
|
|
G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ATP1A1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
|
|
G |
Atp2a1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of ATP2A1 mRNA |
CTD |
PMID:34374793 |
|
NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
|
|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
|
|
G |
Atp5f1b |
ATP synthase F1 subunit beta |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ATP5F1B protein |
CTD |
PMID:19826936 |
|
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
|
|
G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ATP5PD protein |
CTD |
PMID:17904249 |
|
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
|
|
G |
Atp6v0a1 |
ATPase H+ transporting V0 subunit a1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATP6V0A1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
|
|
G |
Atp6v0e2 |
ATPase, H+ transporting V0 subunit e2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ATP6V0E2 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
|
|
G |
Atp6v1b2 |
ATPase H+ transporting V1 subunit B2 |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of ATP6V1B2 protein |
CTD |
PMID:16181420 PMID:19826936 |
|
NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
|
|
G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ATP6V1C2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
|
|
G |
Atxn2 |
ataxin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479
|
|
G |
Atxn2l |
ataxin 2-like |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN2L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686
|
|
G |
Atxn7l1 |
ataxin 7-like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN7L1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320
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|
G |
Aurkc |
aurora kinase C |
decreases expression |
EXP |
Methamphetamine results in decreased expression of AURKC mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386
|
|
G |
Avp |
arginine vasopressin |
affects expression multiple interactions |
EXP |
Methamphetamine affects the expression of AVP mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
B3galt4 |
Beta-1,3-galactosyltransferase 4 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA Methamphetamine results in decreased expression of B3GALT4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
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G |
Bace1 |
beta-secretase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of BACE1 protein |
CTD |
PMID:30367931 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bach2 |
BTB domain and CNC homolog 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BACH2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877
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G |
Baiap3 |
BAI1-associated protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of BAIAP3 mRNA |
CTD |
PMID:25290377 |
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NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
ISO |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein Methamphetamine results in increased expression of BAK1 protein |
CTD |
PMID:23820845 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Banp |
Btg3 associated nuclear protein |
increases expression |
ISO |
Methamphetamine results in increased expression of BANP mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
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G |
Bard1 |
BRCA1 associated RING domain 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of BARD1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein] [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein] Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein] |
CTD |
PMID:19149911 PMID:23820845 PMID:26307267 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:34214594 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Baz1b |
bromodomain adjacent to zinc finger domain, 1B |
increases expression |
ISO |
Methamphetamine results in increased expression of BAZ1B mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
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G |
Baz2a |
bromodomain adjacent to zinc finger domain, 2A |
increases expression |
ISO |
Methamphetamine results in increased expression of BAZ2A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
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G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions increases expression |
ISO EXP |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein] Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BBC3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein] BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein] |
CTD |
PMID:23820845 PMID:26524635 PMID:30394308 PMID:34214594 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
affects response to substance multiple interactions decreases expression increases expression |
ISO EXP |
BCL2 protein affects the susceptibility to Methamphetamine 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; STX17 protein inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein] 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] Methamphetamine results in decreased expression of BCL2 mRNA; Methamphetamine results in decreased expression of BCL2 protein [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] Methamphetamine results in increased expression of BCL2 protein |
CTD |
PMID:11457507 PMID:12050851 PMID:15276877 PMID:19149911 PMID:23820845 PMID:26524635 PMID:26923100 PMID:29297590 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32203791 PMID:32676729 PMID:34214594 PMID:34374793 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
affects expression multiple interactions decreases expression increases expression increases methylation |
EXP ISO |
Methamphetamine affects the expression of BCL2L1 mRNA alternative form [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA Methamphetamine results in decreased expression of BCL2L1 mRNA Methamphetamine results in increased expression of BCL2L1 mRNA Methamphetamine results in increased methylation of BCL2L1 promoter EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:10336889 PMID:23820845 PMID:26307267 PMID:31422080 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions increases expression |
ISO EXP |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein Methamphetamine results in increased expression of BCL2L11 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein] |
CTD |
PMID:23820845 PMID:34214594 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl2l15 |
Bcl2-like 15 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA Methamphetamine results in increased expression of BCL2L15 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
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G |
Bcl2l2 |
Bcl2-like 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BCL2L2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
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G |
Bcl6 |
BCL6, transcription repressor |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA Methamphetamine results in increased expression of BCL6 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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G |
Bcl9l |
BCL9 like |
increases expression |
ISO |
Methamphetamine results in increased expression of BCL9L mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BDH1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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G |
Bdnf |
brain-derived neurotrophic factor |
increases response to substance affects response to substance increases expression decreases expression multiple interactions |
ISO EXP |
BDNF gene SNP results in increased susceptibility to Methamphetamine BDNF gene polymorphism affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of BDNF protein BDNF protein affects the susceptibility to Methamphetamine Methamphetamine results in decreased expression of BDNF protein Metformin inhibits the reaction [Methamphetamine results in decreased expression of BDNF protein] |
CTD |
PMID:15050682 PMID:16039058 PMID:19462300 PMID:20736000 PMID:27373168 PMID:30742852 PMID:34461196 More...
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein] DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein] Methamphetamine results in increased phosphorylation of BECN1 protein NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein] |
CTD |
PMID:26825372 PMID:31059759 PMID:32035215 PMID:32676729 PMID:33359793 PMID:34374793 PMID:37567421 More...
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bhmt2 |
betaine-homocysteine S-methyltransferase 2 |
affects expression multiple interactions |
EXP |
Methamphetamine affects the expression of BHMT2 mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
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G |
Bid |
BH3 interacting domain death agonist |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of BID mRNA; Methamphetamine results in increased expression of BID protein modified form [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form |
CTD |
PMID:23820845 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bin1 |
bridging integrator 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of BIN1 protein |
CTD |
PMID:19826936 |
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NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BIRC5 mRNA |
CTD |
PMID:25290377 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of BMAL1 mRNA; Methamphetamine results in increased expression of BMAL1 protein |
CTD |
PMID:35863504 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of BNIP3 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
increases expression |
EXP |
Methamphetamine results in increased expression of BRAF mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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G |
Brd2 |
bromodomain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRD2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
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G |
Brd9 |
bromodomain containing 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRD9 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:29,329,981...29,357,285
Ensembl chr 1:29,329,985...29,357,016
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G |
Brwd1 |
bromodomain and WD repeat domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRWD1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768
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G |
Bspry |
B-box and SPRY domain containing |
decreases expression |
EXP |
Methamphetamine results in decreased expression of BSPRY mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of BST2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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G |
Btaf1 |
B-TFIID TATA-box binding protein associated factor 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of BTAF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:234,653,219...234,743,903
Ensembl chr 1:234,653,156...234,743,903
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of BTG2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
EXP |
Methamphetamine results in decreased expression of BUB1B mRNA |
CTD |
PMID:28341135 |
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NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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G |
C10h16orf89 |
similar to human chromosome 16 open reading frame 89 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of C10H16ORF89 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of C10H16ORF89 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:10,361,909...10,371,046
Ensembl chr10:10,361,948...10,371,046
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G |
C15h8orf58 |
similar to human chromosome 8 open reading frame 58 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of C15H8ORF58 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of C15H8ORF58 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:45,228,615...45,235,274
Ensembl chr15:45,228,615...45,233,254
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G |
C19h16orf87 |
similar to human chromosome 16 open reading frame 87 |
increases expression |
EXP |
Methamphetamine results in increased expression of C19H16ORF87 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:21,626,390...21,653,869
Ensembl chr19:21,626,914...21,654,255
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G |
C1ql1 |
complement C1q like 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of C1QL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:87,902,125...87,909,556
Ensembl chr10:87,902,137...87,909,310
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G |
C1qtnf7 |
C1q and TNF related 7 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA Methamphetamine results in decreased expression of C1QTNF7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
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G |
C2cd2 |
C2 calcium-dependent domain containing 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of C2CD2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
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G |
C2h3orf33 |
similar to human chromosome 3 open reading frame 33 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of C2H3ORF33 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387
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G |
C3h11orf96 |
similar to human chromosome 11 open reading frame 96 |
increases expression |
EXP |
Methamphetamine results in increased expression of C3H11ORF96 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
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G |
C4bpb |
complement component 4 binding protein, beta |
decreases expression |
EXP |
Methamphetamine results in decreased expression of C4BPB mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
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G |
C5h1orf210 |
similar to human chromosome 1 open reading frame 210 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C5H1ORF210 mRNA Methamphetamine results in decreased expression of C5H1ORF210 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925
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G |
C8g |
complement C8 gamma chain |
decreases expression |
EXP |
Methamphetamine results in decreased expression of C8G mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495
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G |
Cab39l |
calcium binding protein 39-like |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CAB39L mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
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G |
Cabin1 |
calcineurin binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CABIN1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:12,893,314...13,015,357
Ensembl chr20:12,893,358...13,015,357
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G |
Cabyr |
calcium binding tyrosine phosphorylation regulated |
increases expression |
ISO |
Methamphetamine results in increased expression of CABYR mRNA |
CTD |
PMID:26307267 |
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NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840
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G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
decreases methylation increases expression |
ISO EXP |
Methamphetamine results in decreased methylation of CACNA1C promoter Methamphetamine results in increased expression of CACNA1C mRNA; Methamphetamine results in increased expression of CACNA1C protein |
CTD |
PMID:26307267 PMID:35863504 |
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NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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G |
Cacna2d1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
affects response to substance multiple interactions increases expression |
ISO |
CACNA2D1 protein affects the susceptibility to Methamphetamine [gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] Methamphetamine results in increased expression of CACNA2D1 mRNA; Methamphetamine results in increased expression of CACNA2D1 protein |
CTD |
PMID:20340177 PMID:21182903 |
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NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
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G |
Cacnb4 |
calcium voltage-gated channel auxiliary subunit beta 4 |
increases expression |
EXP |
Methamphetamine results in increased expression of CACNB4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
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G |
Cacybp |
calcyclin binding protein |
increases expression |
EXP |
Methamphetamine results in increased expression of CACYBP mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
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G |
Calb2 |
calbindin 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CALB2 mRNA |
CTD |
PMID:28619521 |
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NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
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G |
Calhm2 |
calcium homeostasis modulator family member 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CALHM2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218
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G |
Camta2 |
calmodulin binding transcription activator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CAMTA2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
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G |
Capzb |
capping actin protein of muscle Z-line subunit beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CAPZB protein |
CTD |
PMID:16181420 |
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NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
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G |
Car1 |
carbonic anhydrase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CAR1 protein |
CTD |
PMID:19826936 |
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NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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G |
Car11 |
carbonic anhydrase 11 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CAR11 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191
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G |
Car4 |
carbonic anhydrase 4 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA Methamphetamine results in decreased expression of CAR4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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G |
Car5b |
carbonic anhydrase 5B |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CAR5B mRNA Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr X:30,474,697...30,534,797
Ensembl chr X:30,474,784...30,533,837
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G |
Carhsp1 |
calcium regulated heat stable protein 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
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G |
Carns1 |
carnosine synthase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CARNS1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:201,459,061...201,470,019
Ensembl chr 1:201,459,076...201,469,845
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G |
Casp1 |
caspase 1 |
multiple interactions increases cleavage increases expression |
ISO |
MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein] Methamphetamine results in increased expression of CASP1 protein |
CTD |
PMID:30394308 PMID:33359793 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
increases cleavage multiple interactions increases expression decreases expression |
EXP ISO |
Methamphetamine results in increased cleavage of CASP12 protein CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein] Methamphetamine results in increased expression of CASP12 mRNA; Methamphetamine results in increased expression of CASP12 protein CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein] |
CTD |
PMID:28070110 PMID:28619521 PMID:29705343 PMID:32203791 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp2 |
caspase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CASP2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression increases cleavage affects cleavage decreases cleavage decreases expression |
ISO EXP |
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; [Methamphetamine co-treated with tin protoporphyrin IX] results in increased cleavage of CASP3 protein; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein] Methamphetamine results in increased expression of CASP3 mRNA; Methamphetamine results in increased expression of CASP3 protein modified form 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; Luteolin inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; W 7 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein] Methamphetamine affects the cleavage of CASP3 protein ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP3 protein; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein] |
CTD |
PMID:12391261 PMID:19149911 PMID:19442829 PMID:23933405 PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 PMID:26923100 PMID:27323860 PMID:28341135 PMID:29297590 PMID:29467000 PMID:30450033 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:32382956 PMID:34214594 PMID:34374793 PMID:36914120 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
multiple interactions increases expression |
EXP |
CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA] Methamphetamine results in increased expression of CASP4 mRNA; Methamphetamine results in increased expression of CASP4 protein alternative form |
CTD |
PMID:19149911 PMID:25631491 PMID:28619521 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
increases cleavage |
EXP |
Methamphetamine results in increased cleavage of CASP6 protein |
CTD |
PMID:32676729 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage |
ISO EXP |
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP9 protein; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein] |
CTD |
PMID:27323860 PMID:32676729 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
decreases expression increases activity multiple interactions decreases activity |
ISO EXP |
Methamphetamine results in decreased expression of CAT protein Methamphetamine results in increased activity of CAT protein linalool inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]; Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein] ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein] |
CTD |
PMID:12797468 PMID:19948197 PMID:23041169 PMID:24430743 PMID:29467000 PMID:37729970 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CAV1 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cbll1 |
Cbl proto-oncogene like 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CBLL1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444
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G |
Cbr1 |
carbonyl reductase 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CBR1 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Cbx1 |
chromobox 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CBX1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
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G |
Cbx8 |
chromobox 8 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CBX8 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
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G |
Cc2d1b |
coiled-coil and C2 domain containing 1B |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA Methamphetamine results in decreased expression of CC2D1B mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:123,353,289...123,367,343
Ensembl chr 5:123,353,292...123,367,318
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G |
Ccdc116 |
coiled-coil domain containing 116 |
increases expression |
EXP |
Methamphetamine results in increased expression of CCDC116 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607
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G |
Ccdc117 |
coiled-coil domain containing 117 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CCDC117 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:80,399,236...80,409,824
Ensembl chr14:80,400,294...80,409,659
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G |
Ccdc51 |
coiled-coil domain containing 51 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of CCDC51 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 8:109,722,595...109,741,478
Ensembl chr 8:109,722,557...109,741,472
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G |
Ccdc57 |
coiled-coil domain containing 57 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCDC57 mRNA |
CTD |
PMID:32035215 |
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NCBI chr10:106,092,784...106,196,405
Ensembl chr10:106,092,947...106,196,077
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G |
Cchcr1 |
coiled-coil alpha-helical rod protein 1 |
affects response to substance |
ISO |
CCHCR1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308
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G |
Cck |
cholecystokinin |
multiple interactions |
EXP ISO |
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein] CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] |
CTD |
PMID:27565679 PMID:32916201 |
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NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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G |
Cckbr |
cholecystokinin B receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of CCKBR mRNA |
CTD |
PMID:32916201 |
|
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
EXP |
Methamphetamine results in increased expression of CCL12 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
EXP |
Methamphetamine results in increased expression of CCL4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCL5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCL6 mRNA |
CTD |
PMID:36914120 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA Methamphetamine results in increased expression of CCN1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccna1 |
cyclin A1 |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccna2 |
cyclin A2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCNA2 mRNA; Methamphetamine results in decreased expression of CCNA2 protein |
CTD |
PMID:28341135 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCNB1 mRNA; Methamphetamine results in decreased expression of CCNB1 protein |
CTD |
PMID:28341135 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
decreases expression |
ISO EXP |
Methamphetamine results in decreased expression of CCNB2 mRNA Methamphetamine results in decreased expression of CCNB2 mRNA; Methamphetamine results in decreased expression of CCNB2 protein |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of CCND1 mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne1 |
cyclin E1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCNE1 protein |
CTD |
PMID:28341135 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccnl1 |
cyclin L1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CCNL1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
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G |
Ccnl2 |
cyclin L2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCNL2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:166,416,940...166,428,997
Ensembl chr 5:166,417,508...166,436,882
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases response to substance increases methylation increases expression |
ISO |
CCR2 protein results in increased susceptibility to Methamphetamine Methamphetamine results in increased methylation of CCR2 promoter Methamphetamine results in increased expression of CCR2 mRNA |
CTD |
PMID:20624155 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of CCR5 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCR7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCT2 protein |
CTD |
PMID:19826936 |
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NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CCT5 protein |
CTD |
PMID:19826936 |
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NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd151 |
CD151 molecule (Raph blood group) |
increases expression |
EXP |
Methamphetamine results in increased expression of CD151 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
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G |
Cd177 |
CD177 molecule |
increases expression |
ISO |
Methamphetamine results in increased expression of CD177 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621
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G |
Cd36 |
CD36 molecule |
increases expression |
ISO |
Methamphetamine results in increased expression of CD36 mRNA; Methamphetamine results in increased expression of CD36 protein |
CTD |
PMID:35643125 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3d |
CD3 delta subunit of T-cell receptor complex |
multiple interactions increases expression |
ISO EXP |
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein] |
CTD |
PMID:29705343 |
|
NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
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G |
Cd4 |
Cd4 molecule |
decreases expression multiple interactions |
EXP |
methamphetamine decreases expression of Cd4 protein in spleen methamphetamine cotreated with ionomycin decreases expression of Cd4 protein in spleen |
RGD |
PMID:25678251 PMID:25678251 |
RGD:407446373, RGD:407446373 |
NCBI chr 4:157,668,878...157,695,366
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
affects response to substance |
ISO |
CD55 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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G |
Cd8a |
CD8 subunit alpha |
increases expression |
EXP |
methamphetamine increases expression of CD8a protein in spleen |
RGD |
PMID:25678251 |
RGD:407446373 |
NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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G |
Cdc42ep3 |
CDC42 effector protein 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of CDC42EP3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
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G |
Cdc45 |
cell division cycle 45 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDC45 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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G |
Cdca3 |
cell division cycle associated 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDCA3 mRNA; Methamphetamine results in decreased expression of CDCA3 protein |
CTD |
PMID:28341135 |
|
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDCA7 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdca8 |
cell division cycle associated 8 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDCA8 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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G |
Cdh13 |
cadherin 13 |
affects response to substance |
ISO |
CDH13 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
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G |
Cdh5 |
cadherin 5 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CDH5 mRNA Luteolin inhibits the reaction [Methamphetamine results in increased expression of CDH5 mRNA] |
CTD |
PMID:32035215 |
|
NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdhr2 |
cadherin-related family member 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDHR2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575
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G |
Cdk1 |
cyclin-dependent kinase 1 |
increases expression decreases expression |
EXP |
Methamphetamine results in increased expression of CDK1 mRNA Methamphetamine results in decreased expression of CDK1 mRNA; Methamphetamine results in decreased expression of CDK1 protein |
CTD |
PMID:15644446 PMID:28341135 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk10 |
cyclin-dependent kinase 10 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDK10 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
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G |
Cdk5 |
cyclin-dependent kinase 5 |
multiple interactions increases expression increases expression |
EXP ISO |
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] Methamphetamine results in increased expression of CDK5 protein SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein] methamphetamine increases expression of Cdk5 protein in the ventral tegmental area and nucleus accumbens |
CTD RGD |
PMID:29705343 PMID:32278788 PMID:28782589 |
RGD:401900303 |
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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G |
Cdk6 |
cyclin-dependent kinase 6 |
increases expression |
EXP |
Methamphetamine results in increased expression of CDK6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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G |
Cdk9 |
cyclin-dependent kinase 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDK9 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein] Methamphetamine results in increased expression of CDKN1A mRNA; Methamphetamine results in increased expression of CDKN1A protein |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions increases expression |
EXP ISO |
GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein] |
CTD |
PMID:36914120 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
increases expression |
EXP |
Methamphetamine results in increased expression of CDKN2B mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdpf1 |
cysteine rich, DPF motif domain containing 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDPF1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:116,896,672...116,905,438
Ensembl chr 7:116,901,003...116,905,406
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G |
Cdr2 |
cerebellar degeneration-related protein 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CDR2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472
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G |
Cds2 |
CDP-diacylglycerol synthase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDS2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of CEBPB mRNA; Methamphetamine results in increased expression of CEBPB protein [Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein] |
CTD |
PMID:19564919 PMID:31059759 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cela1 |
chymotrypsin like elastase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CELA1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
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G |
Cenph |
centromere protein H |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CENPH mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154
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G |
Cenpq |
centromere protein Q |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CENPQ mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789
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G |
Cenpw |
centromere protein W |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CENPW mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
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G |
Cep104 |
centrosomal protein 104 |
multiple interactions affects expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA Methamphetamine affects the expression of CEP104 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:164,534,773...164,567,260
Ensembl chr 5:164,534,782...164,567,248
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G |
Cep55 |
centrosomal protein 55 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CEP55 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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G |
Cep72 |
centrosomal protein 72 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CEP72 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 1:29,225,312...29,255,294
Ensembl chr 1:29,225,361...29,255,271
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G |
Cep95 |
centrosomal protein 95 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CEP95 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:91,732,111...91,760,095
Ensembl chr10:91,732,111...91,760,092
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G |
Cert1 |
ceramide transporter 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CERT1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
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G |
Cggbp1 |
CGG triplet repeat binding protein 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CGGBP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:2,565,629...2,572,869
Ensembl chr11:2,565,484...2,573,031
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CHAC1 mRNA |
CTD |
PMID:28619521 |
|
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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G |
Chat |
choline O-acetyltransferase |
decreases activity |
ISO |
Methamphetamine results in decreased activity of CHAT protein |
CTD |
PMID:10089005 |
|
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chd4 |
chromodomain helicase DNA binding protein 4 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of CHD4 promoter Methamphetamine results in increased expression of CHD4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
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G |
Cherp |
calcium homeostasis endoplasmic reticulum protein |
increases expression |
ISO |
Methamphetamine results in increased expression of CHERP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:17,367,455...17,380,507
Ensembl chr16:17,367,455...17,380,507
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G |
Chkb |
choline kinase beta |
increases expression |
ISO |
Methamphetamine results in increased expression of CHKB mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
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G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA Methamphetamine results in increased expression of CHORDC1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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G |
Chrnb1 |
cholinergic receptor nicotinic beta 1 subunit |
increases expression |
EXP |
Methamphetamine results in increased expression of CHRNB1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
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G |
Chrne |
cholinergic receptor nicotinic epsilon subunit |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA Methamphetamine results in increased expression of CHRNE mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
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G |
Chtf18 |
chromosome transmission fidelity factor 18 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA Methamphetamine results in decreased expression of CHTF18 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
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G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CIAPIN1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503
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G |
Cic |
capicua transcriptional repressor |
increases expression |
ISO |
Methamphetamine results in increased expression of CIC mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
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G |
Cidea |
cell death-inducing DFFA-like effector a |
increases expression |
EXP |
Methamphetamine results in increased expression of CIDEA mRNA; Methamphetamine results in increased expression of CIDEA protein |
CTD |
PMID:28341135 |
|
NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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G |
Cirbp |
cold inducible RNA binding protein |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CIRBP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
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G |
Cited2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CITED2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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G |
Cited4 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA Methamphetamine results in decreased expression of CITED4 mRNA Methamphetamine results in increased expression of CITED4 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Ckb |
creatine kinase B |
increases expression |
EXP |
Methamphetamine results in increased expression of CKB protein |
CTD |
PMID:19826936 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clasrp |
CLK4-associating serine/arginine rich protein |
increases expression decreases expression |
ISO EXP |
Methamphetamine results in increased expression of SFRS16 mRNA Methamphetamine results in decreased expression of CLASRP mRNA |
CTD |
PMID:26307267 PMID:32035215 |
|
NCBI chr 1:79,232,260...79,256,462
Ensembl chr 1:79,232,261...79,256,354
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G |
Clcn6 |
chloride voltage-gated channel 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of CLCN6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
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G |
Clcnkb |
chloride voltage-gated channel Kb |
decreases expression affects methylation |
ISO |
Methamphetamine results in decreased expression of CLCNKB mRNA Methamphetamine affects the methylation of CLCNKB promoter |
CTD |
PMID:26307267 |
|
NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
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G |
Cldn5 |
claudin 5 |
decreases expression multiple interactions |
EXP ISO |
Methamphetamine results in decreased expression of CLDN5 mRNA Methamphetamine results in decreased expression of CLDN5 mRNA; Methamphetamine results in decreased expression of CLDN5 protein [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein] |
CTD |
PMID:19564919 PMID:35390362 PMID:36720452 |
|
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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G |
Clec4e |
C-type lectin domain family 4, member E |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CLEC4E mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
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G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
EXP |
Methamphetamine results in increased expression of CLIC4 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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G |
Clip1 |
CAP-GLY domain containing linker protein 1 |
increases expression |
ISO EXP |
Methamphetamine results in increased expression of CLIP1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
|
NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
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G |
Clpx |
caseinolytic mitochondrial matrix peptidase chaperone subunit X |
increases expression |
EXP |
Methamphetamine results in increased expression of CLPX mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
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G |
Cluh |
clustered mitochondria homolog |
increases expression |
ISO |
Methamphetamine results in increased expression of CLUH mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345
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G |
Clvs2 |
clavesin 2 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CLVS2 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
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G |
Cmtm3 |
CKLF-like MARVEL transmembrane domain containing 3 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of CMTM3 promoter |
CTD |
PMID:26307267 |
|
NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790
|
|
G |
Cmtm8 |
CKLF-like MARVEL transmembrane domain containing 8 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CMTM8 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083
|
|
G |
Cnot6l |
CCR4-NOT transcription complex, subunit 6-like |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CNOT6L mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA |
CTD |
PMID:19564919 |
|
NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203
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|
G |
Cnp |
2',3'-cyclic nucleotide 3' phosphodiesterase |
multiple interactions decreases expression |
ISO |
SNCA protein affects the reaction [Methamphetamine results in decreased expression of CNP protein]; TFEB protein inhibits the reaction [Methamphetamine results in decreased expression of CNP protein] |
CTD |
PMID:34562559 |
|
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
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|
G |
Cnr1 |
cannabinoid receptor 1 |
affects response to substance |
EXP |
CNR1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:17953657 |
|
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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|
G |
Cntfr |
ciliary neurotrophic factor receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of CNTFR mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392
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|
G |
Cntn2 |
contactin 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CNTN2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
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G |
Cntnap5b |
contactin associated protein family member 5B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CNTNAP5A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014
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|
G |
Col10a1 |
collagen type X alpha 1 chain |
increases expression |
EXP |
Methamphetamine results in increased expression of COL10A1 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
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G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL15A1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
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G |
Col25a1 |
collagen type XXV alpha 1 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL25A1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:218,755,152...219,154,348
Ensembl chr 2:218,755,691...219,153,501
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|
G |
Col28a1 |
collagen type XXVIII alpha 1 chain |
affects response to substance |
ISO |
COL28A1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 4:36,069,980...36,223,128
Ensembl chr 4:36,069,970...36,223,220
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|
G |
Col3a1 |
collagen type III alpha 1 chain |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of COL3A1 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col6a2 |
collagen type VI alpha 2 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL6A2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
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|
G |
Comt |
catechol-O-methyltransferase |
increases response to substance affects response to substance |
ISO |
COMT gene polymorphism results in increased susceptibility to Methamphetamine COMT gene polymorphism affects the susceptibility to Methamphetamine |
CTD |
PMID:15274053 PMID:19462300 |
|
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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|
G |
Copb2 |
COPI coat complex subunit beta 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of COPB2 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
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G |
Coq10b |
coenzyme Q10B |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA Methamphetamine results in increased expression of COQ10B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663
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|
G |
Coq8a |
coenzyme Q8A |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of COQ8A mRNA Methamphetamine results in decreased methylation of COQ8A promoter |
CTD |
PMID:26307267 |
|
NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
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G |
Corin |
corin, serine peptidase |
increases expression |
ISO |
Methamphetamine results in increased expression of CORIN mRNA |
CTD |
PMID:36914120 |
|
NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503
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|
G |
Coro6 |
coronin 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of CORO6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
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G |
Cox10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
increases expression |
ISO |
Methamphetamine results in increased expression of COX10 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667
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G |
Cp |
ceruloplasmin |
multiple interactions decreases expression |
EXP |
linalool inhibits the reaction [Methamphetamine results in decreased expression of CP protein] |
CTD |
PMID:37729970 |
|
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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|
G |
Cpeb3 |
cytoplasmic polyadenylation element binding protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of CPEB3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
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G |
Cplx1 |
complexin 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CPLX1 protein |
CTD |
PMID:19826936 |
|
NCBI chr14:1,184,677...1,216,392
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|
G |
Cplx2 |
complexin 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CPLX2 protein |
CTD |
PMID:19826936 |
|
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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G |
Cptp |
ceramide-1-phosphate transfer protein |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of CPTP promoter |
CTD |
PMID:26307267 |
|
NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
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|
G |
Cpz |
carboxypeptidase Z |
increases expression |
EXP |
Methamphetamine results in increased expression of CPZ mRNA |
CTD |
PMID:15644446 |
|
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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|
G |
Crabp1 |
cellular retinoic acid binding protein 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CRABP1 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases expression increases activity |
EXP ISO |
Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein Methamphetamine results in increased expression of CREB1 mRNA; Methamphetamine results in increased expression of CREB1 protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 protein] methamphetamine increases activity of Creb1 protein in the ventral tegmental area and nucleus accumbens |
CTD RGD |
PMID:30742852 PMID:33421459 PMID:28782589 |
RGD:401900303 |
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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|
G |
Creb3l1 |
cAMP responsive element binding protein 3-like 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CREB3L1 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
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G |
Creld2 |
cysteine-rich with EGF-like domains 2 |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of CRELD2 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
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G |
Crem |
cAMP responsive element modulator |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA Methamphetamine results in increased expression of CREM mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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|
G |
Crh |
corticotropin releasing hormone |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA Methamphetamine results in increased expression of CRH mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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|
G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
multiple interactions |
EXP |
[CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:17119930 |
|
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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|
G |
Crispld1 |
cysteine-rich secretory protein LCCL domain containing 1 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA Methamphetamine results in decreased expression of CRISPLD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
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G |
Crk |
CRK proto-oncogene, adaptor protein |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CRK protein |
CTD |
PMID:19826936 |
|
NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
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G |
Crkl |
CRK like proto-oncogene, adaptor protein |
increases expression |
EXP |
Methamphetamine results in increased expression of CRKL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
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G |
Crtc2 |
CREB regulated transcription coactivator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CRTC2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:175,709,603...175,719,768
Ensembl chr 2:175,709,644...175,719,763
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G |
Cry1 |
cryptochrome circadian regulator 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CRY1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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G |
Cry2 |
cryptochrome circadian regulator 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of CRY2 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
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G |
Cryab |
crystallin, alpha B |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of CRYAB mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA] |
CTD |
PMID:19564919 |
|
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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G |
Crym |
crystallin, mu |
increases expression |
EXP |
Methamphetamine results in increased expression of CRYM protein |
CTD |
PMID:19826936 |
|
NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
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G |
Cs |
citrate synthase |
increases expression |
EXP |
Methamphetamine results in increased expression of CS mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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|
G |
Csdc2 |
cold shock domain containing C2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSDC2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
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|
G |
Csf1 |
colony stimulating factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf1r |
colony stimulating factor 1 receptor |
increases expression |
EXP |
Methamphetamine results in increased expression of CSF1R mRNA |
CTD |
PMID:32035215 |
|
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSF2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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|
G |
Csmd1 |
CUB and Sushi multiple domains 1 |
affects response to substance |
ISO |
CSMD1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
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|
G |
Csn1s1 |
casein alpha s1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CSN1S1 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614
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|
G |
Csrp2 |
cysteine and glycine-rich protein 2 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of CSRP2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
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|
G |
Cst11 |
cystatin 11 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of CST11 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 3:136,211,414...136,214,138
Ensembl chr 3:136,211,414...136,214,138
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|
G |
Cstb |
cystatin B |
affects expression |
EXP |
Methamphetamine affects the expression of CSTB protein |
CTD |
PMID:17904249 |
|
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
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G |
Ctbp2 |
C-terminal binding protein 2 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of CTBP2 promoter Methamphetamine results in increased expression of CTBP2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:19149911 PMID:32035215 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctrl |
chymotrypsin-like |
increases expression |
EXP |
Methamphetamine results in increased expression of CTRL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
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|
G |
Ctsb |
cathepsin B |
increases activity |
EXP |
Methamphetamine results in increased activity of CTSB protein |
CTD |
PMID:34374793 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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|
G |
Ctsd |
cathepsin D |
affects localization |
EXP |
Methamphetamine affects the localization of CTSD protein |
CTD |
PMID:17105920 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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|
G |
Cubn |
cubilin |
affects response to substance |
ISO |
CUBN gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
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|
G |
Cuedc1 |
CUE domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CUEDC1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542
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|
G |
Cul2 |
cullin 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CUL2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cul9 |
cullin 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of CUL9 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:14,435,948...14,479,552
Ensembl chr 9:14,436,111...14,479,548
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G |
Cux1 |
cut-like homeobox 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CUX1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
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G |
Cwc25 |
CWC25 spliceosome-associated protein homolog |
increases expression |
EXP |
Methamphetamine results in increased expression of CWC25 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
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|
G |
Cx3cr1 |
C-X3-C motif chemokine receptor 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CX3CR1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of CXCL10 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions increases expression |
EXP |
Luteolin inhibits the reaction [Methamphetamine results in increased expression of CXCL12 mRNA] |
CTD |
PMID:32035215 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CXCL2 mRNA |
CTD |
PMID:25290377 PMID:36914120 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of CXCL1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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|
G |
Cyb5b |
cytochrome b5 type B |
increases expression |
EXP |
Methamphetamine results in increased expression of CYB5B mRNA |
CTD |
PMID:19149911 |
|
NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
|
|
G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
EXP |
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] |
CTD |
PMID:27565679 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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|
G |
Cycs |
cytochrome c, somatic |
increases expression |
EXP |
Methamphetamine results in increased expression of CYCS mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of CYP11A1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
affects metabolic processing |
ISO |
CYP1A2 protein affects the metabolism of Methamphetamine metabolite |
CTD |
PMID:16038959 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
|
|
G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
EXP |
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of CYP27A1 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
affects response to substance increases metabolic processing |
ISO |
CYP2D4 gene polymorphism affects the susceptibility to Methamphetamine; CYP2D6 protein affects the susceptibility to Methamphetamine CYP2D6 protein results in increased metabolism of Methamphetamine |
CTD |
PMID:18280655 PMID:20727252 PMID:27320963 |
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NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
affects metabolic processing |
ISO |
CYP2E1 protein affects the metabolism of Methamphetamine metabolite |
CTD |
PMID:16038959 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2j10 |
cytochrome P450, family 2, subfamily j, polypeptide 10 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CYP2J10 mRNA Methamphetamine results in decreased expression of CYP2J10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
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G |
Cyp2t1 |
cytochrome P450, family 2, subfamily t, polypeptide 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CYP2T1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
affects metabolic processing multiple interactions |
ISO |
CYP3A4 protein affects the metabolism of Methamphetamine metabolite [Methamphetamine binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:12851153 PMID:16038959 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4a8 |
cytochrome P450, family 4, subfamily a, polypeptide 8 |
increases expression |
EXP |
Methamphetamine results in increased expression of CYP4A8 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
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G |
Cyp4f4 |
cytochrome P450, family 4, subfamily f, polypeptide 4 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CYP4F4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:35688268 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cyth1 |
cytohesin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CYTH1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
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G |
Cyyr1 |
cysteine and tyrosine rich 1 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA Methamphetamine results in decreased expression of CYYR1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961
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G |
Czib |
CXXC motif containing zinc binding protein |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CZIB mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:122,648,333...122,657,767
Ensembl chr 5:122,648,411...122,656,910
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G |
Dad1 |
defender against cell death 1 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of DAD1 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347
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G |
Dbh |
dopamine beta-hydroxylase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DBH protein |
CTD |
PMID:28661099 |
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NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression affects expression decreases expression |
ISO EXP |
Methamphetamine results in increased expression of DBP mRNA Methamphetamine affects the expression of DBP mRNA Methamphetamine results in decreased expression of DBP mRNA |
CTD |
PMID:26307267 PMID:35863504 PMID:36914120 |
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NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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G |
Dcstamp |
dendrocyte expressed seven transmembrane protein |
affects response to substance |
ISO |
DCSTAMP gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
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G |
Dctn1 |
dynactin subunit 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DCTN1 mRNA; Methamphetamine results in decreased expression of DCTN1 protein |
CTD |
PMID:34374793 |
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NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815
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G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
affects expression |
EXP |
Methamphetamine affects the expression of DDAH1 protein |
CTD |
PMID:17904249 |
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NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression affects localization |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA] Methamphetamine results in increased expression of DDIT3 mRNA; Methamphetamine results in increased expression of DDIT3 protein ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein] Methamphetamine affects the localization of DDIT3 protein |
CTD |
PMID:15644446 PMID:19564919 PMID:27323860 PMID:28070110 PMID:28619521 PMID:32203791 PMID:34214594 More...
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions increases response to substance increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form] DDIT4 protein results in increased susceptibility to Methamphetamine Methamphetamine results in increased expression of DDIT4 mRNA; Methamphetamine results in increased expression of DDIT4 protein DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:19564919 PMID:26825372 PMID:31059759 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddt |
D-dopachrome tautomerase |
affects expression |
EXP |
Methamphetamine affects the expression of DDT protein |
CTD |
PMID:17904249 |
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NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
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G |
Ddx10 |
DEAD-box helicase 10 |
increases expression |
EXP |
Methamphetamine results in increased expression of DDX10 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
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G |
Ddx17 |
DEAD-box helicase 17 |
increases expression |
ISO |
Methamphetamine results in increased expression of DDX17 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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G |
Ddx21 |
DExD-box helicase 21 |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
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G |
Ddx52 |
DExD-box helicase 52 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DDX52 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
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G |
Deaf1 |
DEAF1 transcription factor |
increases expression |
ISO |
Methamphetamine results in increased expression of DEAF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
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G |
Dennd5a |
DENN domain containing 5A |
increases expression |
ISO |
Methamphetamine results in increased expression of DENND5A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316
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G |
Depdc1 |
DEP domain containing 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DEPDC1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
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G |
Depp1 |
DEPP autophagy regulator 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DEPP1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of DGAT2 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Dgkb |
diacylglycerol kinase, beta |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DGKB mRNA |
CTD |
PMID:32035215 |
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NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
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G |
Dgkg |
diacylglycerol kinase, gamma |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKG mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
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G |
Dgkh |
diacylglycerol kinase, eta |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKH mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706
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G |
Dgkz |
diacylglycerol kinase zeta |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKZ mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
increases expression |
EXP |
Methamphetamine results in increased expression of DHCR24 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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G |
Dhx16 |
DEAH-box helicase 16 |
increases expression |
ISO |
Methamphetamine results in increased expression of DHX16 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
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G |
Diaph3 |
diaphanous-related formin 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DIAPH3 mRNA |
CTD |
PMID:28341135 |
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NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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G |
Dicer1 |
dicer 1 ribonuclease III |
increases methylation |
ISO |
Methamphetamine results in increased methylation of DICER1 promoter |
CTD |
PMID:26307267 |
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NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dio2 |
iodothyronine deiodinase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of DIO2 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dipk1a |
divergent protein kinase domain 1A |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DIPK1A mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743
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G |
Dis3 |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
increases expression |
EXP |
Methamphetamine results in increased expression of DIS3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
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G |
Dis3l |
DIS3-like exosome 3'-5' exoribonuclease |
increases expression |
ISO |
Methamphetamine results in increased expression of DIS3L mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165
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G |
Dis3l2 |
DIS3-like 3'-5' exoribonuclease 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of DIS3L2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of DKK1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dlat |
dihydrolipoamide S-acetyltransferase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DLAT protein |
CTD |
PMID:19826936 |
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NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression |
EXP |
Methamphetamine results in increased expression of DLD protein |
CTD |
PMID:19826936 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of DLG4 protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of DLG4 protein] |
CTD |
PMID:33421459 PMID:34461196 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dlgap5 |
DLG associated protein 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DLGAP5 mRNA |
CTD |
PMID:25290377 |
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NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dlst |
dihydrolipoamide S-succinyltransferase |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of DLST mRNA; Methamphetamine results in decreased expression of DLST protein Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of DLST mRNA] |
CTD |
PMID:19149911 PMID:19826936 |
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NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
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G |
Dmd |
dystrophin |
increases expression |
ISO |
Methamphetamine results in increased expression of DMD mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
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G |
Dmkn |
dermokine |
increases expression decreases expression |
EXP |
Methamphetamine results in increased expression of DMKN mRNA Methamphetamine results in decreased expression of DMKN mRNA |
CTD |
PMID:19564919 PMID:32035215 |
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NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006
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G |
Dmpk |
DM1 protein kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of DMPK mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:78,730,255...78,740,585
Ensembl chr 1:78,730,275...78,740,593
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G |
Dmwd |
DM1 locus, WD repeat containing |
increases expression |
ISO |
Methamphetamine results in increased expression of DMWD mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:78,722,436...78,729,224
Ensembl chr 1:78,722,330...78,740,593
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G |
Dnaaf2 |
dynein, axonemal, assembly factor 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of DNAAF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199
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G |
Dnah1 |
dynein, axonemal, heavy chain 1 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA Methamphetamine results in decreased expression of DNAH1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350
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G |
Dnah6 |
dynein, axonemal, heavy chain 6 |
affects expression |
EXP |
Methamphetamine affects the expression of DNAH6 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
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G |
Dnai1 |
dynein, axonemal, intermediate chain 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of DNAI1 mRNA |
CTD |
PMID:34374793 |
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NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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G |
Dnaja4 |
DnaJ heat shock protein family (Hsp40) member A4 |
increases expression |
EXP |
Methamphetamine results in increased expression of DNAJA4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA Methamphetamine results in increased expression of DNAJB4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb5 |
DnaJ heat shock protein family (Hsp40) member B5 |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of DNAJB5 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA] |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 5:57,176,840...57,186,067
Ensembl chr 5:57,176,845...57,185,490
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of DNAJC3 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dnal4 |
dynein, axonemal, light chain 4 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DNAL4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283
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G |
Dnase1 |
deoxyribonuclease 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Methamphetamine results in increased expression of DNASE1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA Methamphetamine results in decreased expression of DNASE1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
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G |
Dnm1 |
dynamin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of DNM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
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G |
Dnmt1 |
DNA methyltransferase 1 |
decreases expression increases expression |
EXP |
Methamphetamine results in decreased expression of DNMT1 mRNA Methamphetamine results in increased expression of DNMT1 mRNA |
CTD |
PMID:17254711 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock6 |
dedicator of cytokinesis 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of DOCK6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:20,342,430...20,394,660
Ensembl chr 8:20,342,089...20,394,552
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G |
Dok3 |
docking protein 3 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of DOK3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
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G |
Dolk |
dolichol kinase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DOLK mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:13,557,826...13,559,864
Ensembl chr 3:13,557,817...13,559,917
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G |
Dpysl2 |
dihydropyrimidinase-like 2 |
affects expression |
EXP |
Methamphetamine affects the expression of DPYSL2 protein |
CTD |
PMID:19826936 |
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NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
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G |
Dpysl3 |
dihydropyrimidinase-like 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DPYSL3 protein |
CTD |
PMID:19826936 |
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NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
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G |
Dpysl5 |
dihydropyrimidinase-like 5 |
increases expression |
EXP |
Methamphetamine results in increased expression of DPYSL5 protein |
CTD |
PMID:19826936 |
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NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422
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G |
Drd1 |
dopamine receptor D1 |
increases expression multiple interactions increases response to substance affects activity decreases expression |
ISO EXP |
Methamphetamine results in increased expression of DRD1 protein [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; bisphenol A promotes the reaction [DRD1 protein results in increased susceptibility to Methamphetamine]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] Methamphetamine affects the activity of DRD1 protein 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein] Methamphetamine results in decreased expression of DRD1 protein |
CTD |
PMID:2891082 PMID:11126397 PMID:11701771 PMID:12617968 PMID:18363855 PMID:18489579 PMID:19444617 PMID:19733155 PMID:20340177 More...
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NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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G |
Drd2 |
dopamine receptor D2 |
increases response to substance multiple interactions affects activity decreases expression increases activity |
ISO EXP |
DRD2 gene polymorphism results in increased susceptibility to Methamphetamine 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD2 protein]; [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein] DRD2 gene results in increased susceptibility to Methamphetamine Methamphetamine results in decreased expression of DRD2 protein Methamphetamine results in increased activity of DRD2 protein [Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] |
CTD |
PMID:2891082 PMID:11126397 PMID:11729018 PMID:17327886 PMID:18363855 PMID:18489579 PMID:18555060 PMID:19046384 PMID:19940168 PMID:20340177 More...
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NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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G |
Drd3 |
dopamine receptor D3 |
decreases expression increases activity |
ISO EXP |
Methamphetamine results in decreased expression of DRD3 protein Methamphetamine results in increased activity of DRD3 protein |
CTD |
PMID:19046384 PMID:19940168 |
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NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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G |
Drd4 |
dopamine receptor D4 |
affects response to substance increases response to substance multiple interactions |
ISO |
DRD4 gene polymorphism affects the susceptibility to Methamphetamine DRD4 gene polymorphism results in increased susceptibility to Methamphetamine [NRA 0160 binds to and results in decreased activity of DRD4 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:10579464 PMID:15274053 PMID:19462300 |
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NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
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G |
Dsp |
desmoplakin |
increases expression |
ISO |
Methamphetamine results in increased expression of DSP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
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G |
Dspp |
dentin sialophosphoprotein |
increases expression |
EXP |
Methamphetamine results in increased expression of DSPP mRNA |
CTD |
PMID:15644446 |
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NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dst |
dystonin |
increases expression |
ISO |
Methamphetamine results in increased expression of DST mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dtl |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DTL mRNA |
CTD |
PMID:25290377 |
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NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
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G |
Dtx3 |
deltex E3 ubiquitin ligase 3 |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of DTX3 mRNA Methamphetamine results in increased methylation of DTX3 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] |
CTD |
PMID:11701771 PMID:19564919 PMID:26307267 |
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NCBI chr10:16,680,478...16,683,275
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G |
Dusp11 |
dual specificity phosphatase 11 |
increases expression |
EXP |
Methamphetamine results in increased expression of DUSP11 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
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G |
Dusp14 |
dual specificity phosphatase 14 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA Methamphetamine results in increased expression of DUSP14 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
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G |
Dusp5 |
dual specificity phosphatase 5 |
increases expression |
EXP |
Methamphetamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
multiple interactions increases expression |
EXP |
[SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] |
CTD |
PMID:11701771 |
|
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Dut |
deoxyuridine triphosphatase |
increases expression |
EXP |
Methamphetamine results in increased expression of DUT mRNA |
CTD |
PMID:19149911 |
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NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
Dux4 |
double homeobox 4 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DUXBL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:1,558,430...1,570,045
Ensembl chr16:1,558,766...1,568,565
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G |
Dydc2 |
DPY30 domain containing 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of DYDC2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr16:16,928,172...16,941,950
Ensembl chr16:16,928,194...16,936,164
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G |
Dysf |
dysferlin |
increases expression |
ISO |
Methamphetamine results in increased expression of DYSF mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709
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G |
Ebi3 |
Epstein-Barr virus induced 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of EBI3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
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G |
Echdc2 |
enoyl CoA hydratase domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ECHDC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859
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G |
Echdc3 |
enoyl CoA hydratase domain containing 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ECHDC3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
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G |
Ect2 |
epithelial cell transforming 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ECT2 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
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G |
Edc4 |
enhancer of mRNA decapping 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of EDC4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758
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G |
Edn3 |
endothelin 3 |
multiple interactions increases expression |
EXP ISO |
GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA] |
CTD |
PMID:36914120 |
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NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
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G |
Eef2k |
eukaryotic elongation factor-2 kinase |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of EEF2K promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
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G |
Efnb1 |
ephrin B1 |
increases expression |
EXP |
Methamphetamine results in increased expression of EFNB1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:64,257,351...64,270,158
Ensembl chr X:64,257,351...64,270,157
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G |
Egfl7 |
EGF-like-domain, multiple 7 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA Methamphetamine results in decreased expression of EGFL7 mRNA Methamphetamine results in increased expression of EGFL7 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
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G |
Egflam |
EGF-like, fibronectin type III and laminin G domains |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of EGFLAM mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of EGLN3 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
EXP ISO |
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA] Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] |
CTD |
PMID:11754491 PMID:15644446 PMID:19564919 PMID:20184921 PMID:20298714 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of EGR2 mRNA |
CTD |
PMID:15644446 PMID:19564919 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Egr4 |
early growth response 4 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of EGR4 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
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G |
Ehbp1l1 |
EH domain binding protein 1-like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of EHBP1L1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EHMT2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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G |
Eif1a |
eukaryotic translation initiation factor 1A |
increases expression |
EXP |
Methamphetamine results in increased expression of EIF1A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form] CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:27323860 PMID:28070110 PMID:29705343 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
EXP |
Methamphetamine results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:28070110 PMID:34214594 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:19054297 |
|
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of EIF4G2 mRNA |
CTD |
PMID:10336889 |
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NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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G |
Elp1 |
elongator acetyltransferase complex subunit 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of ELP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
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G |
Eml1 |
EMAP like 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of EML1 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 6:127,283,968...127,457,246
Ensembl chr 6:127,284,029...127,457,246
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G |
Eml2 |
EMAP like 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EML2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341
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G |
Emsy |
EMSY transcriptional repressor, BRCA2 interacting |
increases expression |
ISO |
Methamphetamine results in increased expression of EMSY mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:152,881,485...152,960,420
Ensembl chr 1:152,883,992...152,953,528
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G |
Eno1 |
enolase 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ENO1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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G |
Eno2 |
enolase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ENO2 protein |
CTD |
PMID:19826936 |
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NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ENPP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
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G |
Enpp6 |
ectonucleotide pyrophosphatase/phosphodiesterase 6 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ENPP6 mRNA |
CTD |
PMID:28619521 |
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NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
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G |
Ep400 |
E1A binding protein p400 |
increases expression |
ISO |
Methamphetamine results in increased expression of EP400 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of EPAS1 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Epb41l1 |
erythrocyte membrane protein band 4.1-like 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of EPB41L1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721
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G |
Epcam |
epithelial cell adhesion molecule |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of EPCAM mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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G |
Ephx1 |
epoxide hydrolase 1 |
increases expression increases methylation multiple interactions |
ISO |
Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein Methamphetamine results in increased methylation of EPHX1 promoter EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein] |
CTD |
PMID:26307267 PMID:31422080 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Epor |
erythropoietin receptor |
decreases expression |
EXP |
Methamphetamine results in decreased expression of EPOR mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions increases phosphorylation |
EXP ISO |
Methamphetamine results in increased expression of ERN1 protein modified form Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form] ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:27323860 PMID:28070110 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Errfi1 |
ERBB receptor feedback inhibitor 1 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA Methamphetamine results in increased expression of ERRFI1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
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G |
Esr1 |
estrogen receptor 1 |
increases response to substance |
ISO |
ESR1 gene polymorphism results in increased susceptibility to Methamphetamine |
CTD |
PMID:19386276 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Etl4 |
enhancer trap locus 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of ETL4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715
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G |
Evc2 |
EvC ciliary complex subunit 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of EVC2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr14:73,366,832...73,454,539
Ensembl chr14:73,367,963...73,454,516
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G |
Exoc7 |
exocyst complex component 7 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of EXOC7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:101,521,630...101,540,425
Ensembl chr10:101,520,927...101,540,561
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G |
F11r |
F11 receptor |
multiple interactions increases expression |
EXP |
Luteolin inhibits the reaction [Methamphetamine results in increased expression of F11R mRNA] |
CTD |
PMID:32035215 |
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NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions decreases expression |
EXP |
linalool inhibits the reaction [Methamphetamine results in decreased expression of F2 protein] |
CTD |
PMID:37729970 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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G |
F3 |
coagulation factor III, tissue factor |
increases methylation |
ISO |
Methamphetamine results in increased methylation of F3 promoter |
CTD |
PMID:26307267 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Faah |
fatty acid amide hydrolase |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA Methamphetamine results in decreased expression of FAAH mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G |
Fabp3 |
fatty acid binding protein 3 |
affects response to substance increases expression |
ISO |
FABP3 affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of FABP3 mRNA |
CTD |
PMID:20181611 PMID:25290377 |
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NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
EXP |
Methamphetamine affects the expression of FABP7 protein |
CTD |
PMID:17904249 |
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NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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G |
Fah |
fumarylacetoacetate hydrolase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FAH mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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G |
Fam110a |
family with sequence similarity 110, member A |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FAM110A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:140,474,484...140,485,074
Ensembl chr 3:140,474,249...140,485,093
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G |
Fam193a |
family with sequence similarity 193, member A |
increases expression |
ISO |
Methamphetamine results in increased expression of FAM193A mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:76,250,103...76,382,525
Ensembl chr14:76,256,161...76,382,514
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G |
Fam193b |
family with sequence similarity 193, member B |
increases expression |
ISO |
Methamphetamine results in increased expression of FAM193B mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:9,066,818...9,099,511
Ensembl chr17:9,066,707...9,099,508
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G |
Fank1 |
fibronectin type III and ankyrin repeat domains 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FANK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:188,577,512...188,685,501
Ensembl chr 1:188,577,575...188,685,504
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G |
Fas |
Fas cell surface death receptor |
decreases expression increases expression |
EXP |
Methamphetamine results in decreased expression of FAS mRNA Methamphetamine results in increased expression of FAS mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases expression |
EXP |
Methamphetamine results in increased expression of FASLG mRNA; Methamphetamine results in increased expression of FASLG protein |
CTD |
PMID:15644446 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fastkd3 |
FAST kinase domains 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FASTKD3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973
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G |
Fblim1 |
filamin binding LIM protein 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of FBLIM1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
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G |
Fbxl4 |
F-box and leucine-rich repeat protein 4 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FBXL4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
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G |
Fbxo28 |
F-box protein 28 |
increases expression |
EXP |
Methamphetamine results in increased expression of FBXO28 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:93,995,993...94,021,464
Ensembl chr13:93,995,996...94,021,464
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G |
Fbxo32 |
F-box protein 32 |
increases expression |
ISO |
Methamphetamine results in increased expression of FBXO32 mRNA |
CTD |
PMID:23933405 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fbxo33 |
F-box protein 33 |
increases expression |
EXP |
Methamphetamine results in increased expression of FBXO33 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669
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G |
Fcgbp |
Fc gamma binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FCGBP mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of FGF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf4 |
fibroblast growth factor 4 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA Methamphetamine results in increased expression of FGF4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of FGFR3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
affects response to substance |
ISO |
FHIT gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
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G |
Fjx1 |
four-jointed box kinase 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FJX1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
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G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
affects response to substance |
ISO |
FKBP15 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
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G |
Fkbp4 |
FKBP prolyl isomerase 4 |
increases expression |
EXP |
Methamphetamine results in increased expression of FKBP4 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
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G |
Flna |
filamin A |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNA mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
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G |
Flnb |
filamin B |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNB mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
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G |
Flnc |
filamin C |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNC mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
increases expression |
ISO EXP |
Methamphetamine results in increased expression of FLT1 mRNA |
CTD |
PMID:26307267 PMID:32035215 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Fmo2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of FMO2 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
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G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
increases metabolic processing |
ISO |
FMO3 protein results in increased metabolism of Methamphetamine |
CTD |
PMID:27320963 |
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NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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G |
Fn1 |
fibronectin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of FN1 mRNA |
CTD |
PMID:12766323 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions affects response to substance increases expression |
ISO EXP |
Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]; Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]] FOS mRNA affects the susceptibility to Methamphetamine; FOS protein affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of FOS; Methamphetamine results in increased expression of FOS protein [Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; Carbamazepine inhibits the reaction [Methamphetamine results in increased expression of FOS protein]; Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein] Methamphetamine results in increased expression of FOS mRNA; Methamphetamine results in increased expression of FOS protein |
CTD |
PMID:10559418 PMID:10731628 PMID:11754491 PMID:12050851 PMID:19564919 PMID:19689456 PMID:20731630 PMID:20950675 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
methamphetamine increases expression of Fosb protein in the ventral tegmental area and nucleus accumbens |
RGD |
PMID:28782589 |
RGD:401900303 |
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
EXP |
Methamphetamine results in increased expression of FOSL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Foxe1 |
forkhead box E1 |
increases expression |
EXP |
Methamphetamine results in increased expression of FOXE1 mRNA; Methamphetamine results in increased expression of FOXE1 protein |
CTD |
PMID:28341135 |
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NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835
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G |
Foxo3 |
forkhead box O3 |
decreases phosphorylation affects localization multiple interactions increases phosphorylation |
EXP |
Methamphetamine results in decreased phosphorylation of FOXO3 protein Methamphetamine affects the localization of FOXO3 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein] Methamphetamine results in increased phosphorylation of FOXO3 protein |
CTD |
PMID:34214594 PMID:35863504 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Fst |
follistatin |
decreases expression |
EXP |
Methamphetamine results in decreased expression of FST mRNA |
CTD |
PMID:28619521 |
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NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
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G |
Ftcd |
formimidoyltransferase cyclodeaminase |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA Methamphetamine results in increased expression of FTCD mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
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G |
Fuz |
fuzzy planar cell polarity protein |
increases expression |
ISO |
Methamphetamine results in increased expression of FUZ mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of FYN mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Gabarapl2 |
GABA type A receptor associated protein like 2 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of GABARAPL2 promoter |
CTD |
PMID:26307267 |
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NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628 Ensembl chr 8:39,910,534...39,924,628
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:21729720 |
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NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
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G |
Gabpa |
GA binding protein transcription factor subunit alpha |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of GABPA mRNA Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA] |
CTD |
PMID:19149911 |
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NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
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G |
Gabra1 |
gamma-aminobutyric acid type A receptor subunit alpha 1 |
multiple interactions |
ISO |
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:21729720 |
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NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
increases response to substance multiple interactions |
ISO |
GABRG2 gene results in increased susceptibility to Methamphetamine Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:15772696 PMID:21729720 |
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NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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G |
Gabrg3 |
gamma-aminobutyric acid type A receptor subunit gamma 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of GABRG3 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
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G |
Gabrr3 |
gamma-aminobutyric acid type A receptor subunit rho3 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of GABRR3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
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G |
Gad2 |
glutamate decarboxylase 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of GAD2 mRNA |
CTD |
PMID:15601951 |
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NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA Methamphetamine results in increased expression of GADD45B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of GADD45G mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Gal |
galanin and GMAP prepropeptide |
increases expression decreases expression |
ISO EXP |
Methamphetamine results in increased expression of GAL mRNA Methamphetamine results in decreased expression of GAL mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Galk1 |
galactokinase 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GALK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
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G |
Galntl6 |
polypeptide N-acetylgalactosaminyltransferase-like 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GALNTL6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:31,192,880...32,443,979
Ensembl chr16:31,186,462...32,441,960
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G |
Galt |
galactose-1-phosphate uridylyltransferase |
increases expression |
ISO |
Methamphetamine results in increased expression of GALT mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
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G |
Gap43 |
growth associated protein 43 |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [Methamphetamine results in decreased expression of GAP43 protein] |
CTD |
PMID:19409439 |
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NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
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G |
Garin5a |
golgi associated RAB2 interactor 5A |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GARIN5A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
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G |
Gas5 |
growth arrest specific 5 |
increases expression |
EXP |
Methamphetamine results in increased expression of GAS5 mRNA |
CTD |
PMID:28619521 |
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NCBI chr13:73,303,611...73,306,932
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G |
Gas8 |
growth arrest specific 8 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA Methamphetamine results in decreased expression of GAS8 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
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G |
Gata4 |
GATA binding protein 4 |
increases expression multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of GATA4 mRNA; Methamphetamine results in increased expression of GATA4 protein GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of TGFB2 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein] |
CTD |
PMID:36914120 |
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NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gatad2b |
GATA zinc finger domain containing 2B |
increases expression |
EXP |
Methamphetamine results in increased expression of GATAD2B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
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G |
Gbf1 |
golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GBF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042
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G |
Gbgt1 |
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) |
increases expression |
EXP |
Methamphetamine results in increased expression of GBGT1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 3:11,826,131...11,829,745
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G |
Gch1 |
GTP cyclohydrolase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of GCH1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
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G |
Gcsh |
glycine cleavage system protein H |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GCSH mRNA |
CTD |
PMID:19149911 |
|
NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792
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G |
Gda |
guanine deaminase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GDA protein |
CTD |
PMID:19826936 |
|
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of GDF15 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA] |
CTD |
PMID:19564919 PMID:25290377 PMID:36914120 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gdi1 |
GDP dissociation inhibitor 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GDI1 protein |
CTD |
PMID:19826936 |
|
NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272
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G |
Gdnf |
glial cell derived neurotrophic factor |
decreases response to substance |
ISO |
GDNF protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:17356005 |
|
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA Methamphetamine results in increased expression of GEM mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions affects expression increases expression |
ISO EXP |
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; Raclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein] Methamphetamine affects the expression of GFAP protein Methamphetamine results in increased expression of GFAP mRNA; Methamphetamine results in increased expression of GFAP protein |
CTD |
PMID:9427479 PMID:9634552 PMID:9739098 PMID:10773198 PMID:12766323 PMID:15337264 PMID:15644446 PMID:16088948 PMID:17262233 PMID:19834288 PMID:21867746 PMID:24072398 PMID:26283213 PMID:28919515 PMID:29467000 PMID:32278788 More...
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Gfra2 |
GDNF family receptor alpha 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of GFRA2 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
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G |
Gfra4 |
GDNF family receptor alpha 4 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of GFRA4 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
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G |
Gigyf1 |
GRB10 interacting GYF protein 1 |
increases methylation increases expression |
ISO |
Methamphetamine results in increased methylation of GIGYF1 promoter Methamphetamine results in increased expression of GIGYF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023
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G |
Gigyf2 |
GRB10 interacting GYF protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GIGYF2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
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G |
Gipc3 |
GIPC PDZ domain containing family, member 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GIPC3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:8,374,941...8,383,281
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G |
Gja4 |
gap junction protein, alpha 4 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GJA4 mRNA Methamphetamine results in decreased expression of GJA4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
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G |
Gja5 |
gap junction protein, alpha 5 |
increases expression |
EXP |
Methamphetamine results in increased expression of GJA5 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
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G |
Glb1 |
galactosidase, beta 1 |
multiple interactions increases expression |
EXP |
GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein] |
CTD |
PMID:36914120 |
|
NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Gli1 |
GLI family zinc finger 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GLI1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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G |
Glo1 |
glyoxalase 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of GLO1 protein |
CTD |
PMID:19826936 |
|
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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G |
Gls |
glutaminase |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
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G |
Glyctk |
glycerate kinase |
increases methylation |
ISO |
Methamphetamine results in increased methylation of GLYCTK promoter |
CTD |
PMID:26307267 |
|
NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397
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G |
Gm2a |
ganglioside GM2 activator |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GM2A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
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G |
Gmfb |
glia maturation factor, beta |
affects expression |
EXP |
Methamphetamine affects the expression of GMFB protein |
CTD |
PMID:17904249 |
|
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
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G |
Gnb1 |
G protein subunit beta 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GNB1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
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G |
Gnb2 |
G protein subunit beta 2 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GNB2 protein |
CTD |
PMID:19826936 |
|
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
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G |
Gnb3 |
G protein subunit beta 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GNB3 protein |
CTD |
PMID:19826936 |
|
NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
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G |
Golgb1 |
golgin B1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GOLGB1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
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G |
Golph3 |
golgi phosphoprotein 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of GOLPH3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049
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G |
Gon4l |
gon-4 like |
increases expression |
ISO |
Methamphetamine results in increased expression of GON4L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
Methamphetamine results in increased expression of GPNMB mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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G |
Gpr150 |
G protein-coupled receptor 150 |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GPR150 mRNA Methamphetamine results in decreased expression of GPR150 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:5,546,304...5,550,889
Ensembl chr 2:5,548,578...5,550,714
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G |
Gpr17 |
G protein-coupled receptor 17 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GPR17 mRNA |
CTD |
PMID:28619521 |
|
NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
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G |
Gpr19 |
G protein-coupled receptor 19 |
increases expression |
EXP |
Methamphetamine results in increased expression of GPR19 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036
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G |
Gpr4 |
G protein-coupled receptor 4 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR4 mRNA Methamphetamine results in increased expression of GPR4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
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G |
Gpr65 |
G-protein coupled receptor 65 |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR65 mRNA Methamphetamine results in increased expression of GPR65 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
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G |
Gpsm1 |
G-protein signaling modulator 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GPSM1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions decreases expression |
EXP |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
affects response to substance multiple interactions |
ISO |
GPX1 protein affects the susceptibility to Methamphetamine GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; Methamphetamine affects the expression of and affects the activity of GPX1 protein; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] |
CTD |
PMID:34082047 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Grb2 |
growth factor receptor bound protein 2 |
affects expression |
EXP |
Methamphetamine affects the expression of GRB2 protein |
CTD |
PMID:17904249 |
|
NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
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G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
affects expression increases expression |
EXP |
Methamphetamine affects the expression of GRIA1 mRNA Methamphetamine increases expression of Gria1 protein in hippocampus, striatum, prefrontal cortex |
CTD RGD |
PMID:18419818 PMID:37778205 |
RGD:405100237 |
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of GRIA2 mRNA; Methamphetamine results in increased expression of GRIA2 protein 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine inhibits the reaction [Methamphetamine results in increased expression of GRIA2 protein] |
CTD |
PMID:18419818 PMID:23711322 |
|
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Gria3 |
glutamate ionotropic receptor AMPA type subunit 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of GRIA3 mRNA |
CTD |
PMID:18419818 |
|
NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of GRIN1 mRNA |
CTD |
PMID:18419818 |
|
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
increases expression |
EXP |
Methamphetamine results in increased expression of GRIN2A mRNA |
CTD |
PMID:18419818 |
|
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
increases expression decreases expression |
ISO EXP |
Methamphetamine results in increased expression of GRIN2B protein Methamphetamine results in increased expression of GRIN2B mRNA Methamphetamine results in decreased expression of GRIN2B mRNA |
CTD |
PMID:17105907 PMID:18419818 PMID:32035215 PMID:32203791 |
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NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Grin2d |
glutamate ionotropic receptor NMDA type subunit 2D |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GRIN2D mRNA |
CTD |
PMID:21886566 |
|
NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
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G |
Grina |
glutamate ionotropic receptor NMDA type subunit associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRINA mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
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G |
Grip2 |
glutamate receptor interacting protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIP2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
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G |
Gripap1 |
GRIP1 associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIPAP1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr X:14,678,896...14,708,747
Ensembl chr X:14,678,898...14,708,679
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G |
Grm1 |
glutamate metabotropic receptor 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of GRM1 mRNA |
CTD |
PMID:18419818 |
|
NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
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G |
Grm2 |
glutamate metabotropic receptor 2 |
increases response to substance multiple interactions |
ISO |
GRM2 gene SNP results in increased susceptibility to Methamphetamine [Piperidines results in increased activity of GRM2 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:20211215 PMID:21366332 |
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NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
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G |
Grm3 |
glutamate metabotropic receptor 3 |
decreases expression increases expression |
EXP |
Methamphetamine results in decreased expression of GRM3 mRNA Methamphetamine results in increased expression of GRM3 mRNA |
CTD |
PMID:15644446 PMID:18419818 |
|
NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
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G |
Grm5 |
glutamate metabotropic receptor 5 |
multiple interactions increases expression |
EXP |
[6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in decreased abundance of Dopamine]; [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in increased secretion of Dopamine] Methamphetamine results in increased expression of GRM5 mRNA; Methamphetamine results in increased expression of GRM5 protein |
CTD |
PMID:12907309 PMID:18419818 PMID:23711322 |
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NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
decreases expression multiple interactions affects phosphorylation |
ISO |
Methamphetamine results in decreased expression of GSK3A protein Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3A protein] |
CTD |
PMID:16192988 PMID:31270305 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation decreases phosphorylation affects phosphorylation increases expression |
ISO EXP |
Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GSK3B protein modified form]; TWS 119 inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein] Methamphetamine results in decreased phosphorylation of GSK3B protein Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3B protein] Metformin inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein |
CTD |
PMID:29981415 PMID:30367931 PMID:30742852 PMID:31270305 PMID:32278788 PMID:35863504 More...
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity |
EXP |
Metformin inhibits the reaction [Methamphetamine results in decreased activity of GSR protein] |
CTD |
PMID:30742852 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of GSTA3 mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gstm1 |
glutathione S-transferase mu 1 |
affects response to substance decreases response to substance |
ISO |
GSTM1 gene polymorphism affects the susceptibility to Methamphetamine GSTM1 protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:15048646 PMID:19254865 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases response to substance |
ISO |
GSTP1 exon polymorphism results in increased susceptibility to Methamphetamine |
CTD |
PMID:15729709 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
affects response to substance |
ISO |
GSTT1 gene polymorphism affects the susceptibility to Methamphetamine; GSTT1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:18186040 PMID:19254865 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Gtpbp10 |
GTP binding protein 10 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of GTPBP10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:28,476,857...28,494,375
Ensembl chr 4:28,476,857...28,494,375
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G |
Gtsf2 |
gametocyte specific factor 2 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of GTSF2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of GTSF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:134,565,889...134,572,047
Ensembl chr 7:134,565,889...134,572,047
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G |
H3f3a |
H3.3 histone A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of H3F3A mRNA |
CTD |
PMID:26307267 |
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NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of HAVCR1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of HAVCR1 protein] |
CTD |
PMID:37567421 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hba-a3 |
hemoglobin alpha, adult chain 3 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HBA-A3 mRNA |
CTD |
PMID:32035215 |
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NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
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G |
Hcn4 |
hyperpolarization activated cyclic nucleotide-gated potassium channel 4 |
increases expression |
EXP |
Methamphetamine results in increased expression of HCN4 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
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G |
Hcrt |
hypocretin neuropeptide precursor |
increases methylation affects expression multiple interactions |
ISO EXP |
Methamphetamine results in increased methylation of HCRT promoter Methamphetamine affects the expression of HCRT mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of HCRT mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
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G |
Hdac10 |
histone deacetylase 10 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HDAC10 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
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G |
Hdac11 |
histone deacetylase 11 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HDAC11 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405
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G |
Hdac6 |
histone deacetylase 6 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HDAC6 mRNA |
CTD |
PMID:25452209 |
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NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
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G |
Hdac7 |
histone deacetylase 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of HDAC7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072
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G |
Hdac8 |
histone deacetylase 8 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HDAC8 mRNA |
CTD |
PMID:25452209 |
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NCBI chr X:67,385,288...67,593,014
Ensembl chr X:67,385,289...67,592,923
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G |
Hdac9 |
histone deacetylase 9 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HDAC9 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdc |
histidine decarboxylase |
multiple interactions affects response to substance |
ISO |
HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid] HDC protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12421355 |
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NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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G |
Herc2 |
HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of HERC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of HERPUD1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HERPUD1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HERPUD1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
Hes1 |
hes family bHLH transcription factor 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of HES1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hes5 |
hes family bHLH transcription factor 5 |
decreases expression multiple interactions |
EXP |
Methamphetamine results in decreased expression of HES5 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of HES5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
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G |
Hist1h4b |
histone cluster 1 H4 family member B |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of HIST1H4B mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HIST1H4B mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
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G |
Hjurp |
Holliday junction recognition protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HJURP mRNA |
CTD |
PMID:25290377 |
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NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
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G |
Hk1 |
hexokinase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of HK1 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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G |
Hmbs |
hydroxymethylbilane synthase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HMBS mRNA |
CTD |
PMID:24042092 |
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NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of HMGA1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
EXP ISO |
[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; [Methamphetamine co-treated with SCH 23390] results in increased expression of HMOX1 mRNA; [tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Methamphetamine promotes the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Methamphetamine results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Methamphetamine results in increased activity of HMOX1 protein] Methamphetamine results in increased expression of HMOX1 mRNA; Methamphetamine results in increased expression of HMOX1 protein sulforaphane promotes the reaction [Methamphetamine results in increased expression of HMOX1 protein] |
CTD |
PMID:19564919 PMID:19576919 PMID:23022510 PMID:23933405 PMID:28619521 PMID:37567421 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Homer1 |
homer scaffold protein 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of HOMER1 mRNA; Methamphetamine results in increased expression of HOMER1 mRNA alternative form; Methamphetamine results in increased expression of HOMER1 protein alternative form |
CTD |
PMID:15644446 PMID:17630046 |
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NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
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G |
Hoxc10 |
homeo box C10 |
decreases methylation decreases expression |
ISO |
Methamphetamine results in decreased methylation of HOXC10 promoter Methamphetamine results in decreased expression of HOXC10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
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G |
Hpca |
hippocalcin |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HPCA mRNA |
CTD |
PMID:15644446 |
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NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
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G |
Hpse |
heparanase |
increases methylation |
ISO |
Methamphetamine results in increased methylation of HPSE promoter |
CTD |
PMID:26307267 |
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NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
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G |
Hr |
HR, lysine demethylase and nuclear receptor corepressor |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HR mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
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G |
Hras |
HRas proto-oncogene, GTPase |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HRAS mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hrc |
histidine rich calcium binding protein |
multiple interactions decreases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HRC mRNA Methamphetamine results in decreased expression of HRC mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
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G |
Hrk |
harakiri, BCL2 interacting protein |
increases expression |
ISO |
Methamphetamine results in increased expression of HRK mRNA |
CTD |
PMID:25290377 |
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NCBI chr12:38,387,484...38,409,652
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G |
Hs3st4 |
heparan sulfate-glucosamine 3-sulfotransferase 4 |
affects response to substance |
ISO |
HS3ST4 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:178,539,078...178,944,850
Ensembl chr 1:178,539,093...178,944,107
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G |
Hscb |
HscB mitochondrial iron-sulfur cluster co-chaperone |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HSCB mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
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G |
Hsd3b7 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HSD3B7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442
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G |
Hsf2bp |
heat shock transcription factor 2 binding protein |
multiple interactions increases expression |
EXP |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HSF2BP mRNA Methamphetamine results in increased expression of HSF2BP mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
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