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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:metaproterenol
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Accession:CHEBI:6792 term browser browse the term
Definition:A phenylethanolamine that has formula C11H17NO3.
Synonyms:related_synonym: Formula=C11H17NO3;   InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3;   InChIKey=LMOINURANNBYCM-UHFFFAOYSA-N;   Metaproterenol polistirex;   Orciprenaline;   SMILES=CC(C)NCC(O)c1cc(O)cc(O)c1
 xref: CAS:586-06-1;   HMDB:HMDB0014954;   KEGG:C07144;   KEGG:D08300
 xref_mesh: MESH:D009921



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metaproterenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 decreases expression
multiple interactions
increases phosphorylation
affects expression
increases activity
ISO Metaproterenol results in decreased expression of ADRB2 protein
[Metaproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; Metaproterenol binds to and results in increased activity of ADRB2 protein
Metaproterenol results in increased phosphorylation of ADRB2 protein
Metaproterenol affects the expression of ADRB2 mRNA
Metaproterenol results in increased activity of ADRB2 protein
CTD PMID:16980553 PMID:24705868 PMID:34601065 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Metaproterenol results in increased expression of BAX protein CTD PMID:15052282 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Metaproterenol results in increased expression of BCAT1 mRNA CTD PMID:23558518 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Metaproterenol results in decreased expression of BCL2 protein CTD PMID:15052282 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Metaproterenol results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr10:16,891,317...16,903,561
Ensembl chr10:16,386,841...16,399,157
JBrowse link
G Clu clusterin increases expression ISO Metaproterenol results in increased expression of CLU protein CTD PMID:15052282 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression EXP Metaproterenol results in increased expression of FABP3 protein CTD PMID:22878004 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Metaproterenol results in increased expression of FHL1 mRNA CTD PMID:23558518 NCBI chr  X:139,592,794...139,652,290
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Metaproterenol results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Metaproterenol results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Metaproterenol results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Metaproterenol results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:85,284,335...85,503,044
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Metaproterenol results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Metaproterenol results in increased expression of RND1 mRNA CTD PMID:23558518 NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:129,821,311...129,828,399
JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP Metaproterenol results in increased expression of SERPINE1 mRNA CTD PMID:23558518 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Metaproterenol results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP Metaproterenol results in increased expression of SPP1 mRNA CTD PMID:23558518 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Metaproterenol results in increased expression of TGFB2 mRNA CTD PMID:23558518 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Metaproterenol results in increased expression of TIMP1 mRNA CTD PMID:23558518 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Metaproterenol results in increased expression of TNNI3 protein CTD PMID:22878004 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression EXP Metaproterenol results in increased expression of TNNT2 protein CTD PMID:22878004 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:47,267,204...47,285,388
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19879
    role 19850
      application 19693
        NMR chemical shift reference compound 18074
          ammonia 17871
            organic amino compound 17871
              amino alcohol 1079
                ethanolamines 826
                  phenylethanolamines 608
                    metaproterenol 21
                      orciprenaline sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    main group molecular entity 19816
                      s-block molecular entity 19651
                        hydrogen molecular entity 19633
                          hydrides 19147
                            inorganic hydride 18160
                              pnictogen hydride 18150
                                nitrogen hydride 18063
                                  azane 17872
                                    ammonia 17871
                                      organic amino compound 17871
                                        amino alcohol 1079
                                          ethanolamines 826
                                            phenylethanolamines 608
                                              metaproterenol 21
                                                orciprenaline sulfate 0
paths to the root